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SUGINO Akio
杉野 明雄
Connect your ORCID iD
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Researcher Number
90231737
Affiliation (based on the past Project Information)
*help
2006: 大阪大学, 大学院生命機能研究科, 教授
2006: 阪大, 教授
2003 – 2005: 大阪大学, 大学院・生命機能研究科, 教授
2003 – 2004: 大阪大学, 生命機能研究科, 教授
2002: 教授
…
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1992 – 2001: 大阪大学, 微生物病研究所, 教授
1993: 大阪大学, 微生物研究所, 教授
1992 – 1993: 大阪大学, 微研, 教授
Less
Review Section/Research Field
Principal Investigator
Molecular biology
/
Biological Sciences
/
Molecular biology
Except Principal Investigator
Cell biology
/
Molecular biology
Keywords
Principal Investigator
出芽酵母 / DNAポリメラーゼ / Cdc7 / 細胞周期 / DNAヘリカーゼ / クローニング / 染色体DNA複製 / DNAポリメラーゼε / Dbf4 protein kinase / 蛋白リン酸化酵素
…
More
/ 分裂酵母 / 遺伝子発現 / Saccharomyces cerevisiae / In vitro DNA複製 / Cdc7-Dbf4複合体 / Eukaryotic chromosomal DNA replication / RF-C複合体 / Dbf4 protein kinase complex / Dbf4複合体 / 染色体複製開始 / CDC7-DBF4複合体 / チェックポイントコントロール / multicopy suppressor / ORC複合体 / 真核細胞染色体複製 / CDC / 一本鎖DNA結合蛋白 / DNAポリメラーゼα-プライマーゼ / ヒト染色体DNA複製開始 / CDC7遺伝子 / 突然変異株 / ガン化の機構 / ショウジョウバエ / 発生と分化 / PCR / 染色体DNA複製開始 / protein kinase / 出芽酵母S.cerevisiae / CDC7 / DBF4 / CDC7 homolog / Northern hybridization / Drosophila melanogaster / DNA polymerase II / 塩基配列 / DNA repair / DNA ポリメラーゼβ / DNA ポリメラーゼε / Yeast Saccharomyces cerevisiae / in vitro DNA repair / double strand break repair / DNA修復 / DNAポリメラーゼβ / YEL055C / 染色体複製 / アフリカツメガエル / 哺乳動物細胞 / チェックポイント / ほ乳動物細胞 / pre RC(複製開始前複合体) / Mcm蛋白 / Cdc / Db4f protein kinase / GINS / Polε複合体 / アフリカツメガエル卵粗抽出液 / セントロメア / 複製開始 / pre RC (複製開始名複合体) / 遺伝学 / 癌 / マウスES細胞 / ミューテーター / 真核細胞染色体DNA複製 / DNAボリメラーゼ / DNAポリメラーゼサブユニット / 細胞周期チェックポイントコントロール / Phosphatase / 細胞周期チェックポイント制御 / ORC蛋白 / 複製開始部位 / DNAポリメラーゼ補助因子 / 蛋白精製 / DNA polymerase II (epsilon) / DNA polymerase III (delta) / DNA polymerase subunits / three DNA polymerase model / Cdc 7-Dbf4 complex / phosphatase / DNA複製複合体 / 多量発現ベクター / バキューロウイルスベクター / 昆虫細胞 / Cdc7-Dbf4 protein kinase複合体 / DNAポリメラーゼ複合体 / バキュロウイルスベクター / YACベクター / RFC複合体 / DNA Replication protein complex / Expression vector / Baculovirus expression vector / Insect cells / Budding yeast / RF-C complex / DNA polymerase complex / 複製ライセンス因子 / Mcm蛋白群 / 複製開始因子 / ORC / Dbf-Cdc7複合体 / S.cerevisiae / S.pombe / Mcm2-7 proteins / Mcm10 / DNA polymeraseII (epsilon) / Dpb11 / Sld / 真核生物染色体複製機構 / Leading鎖複製装置 / Lagging鎖複製装置 / Mcm2-7蛋白複合体 / Dbf4プロテインキナーゼ / チェックポイント制御 / Bloom症候群原因遺伝子産物 / ヘリカーゼ / Mcm蛋白複合体 / 真核生物染色体DNA複製 / Leading鎖合成装置 / Lagging鎖合成装置 / PCNA / 細胞周期チェックポイント / Leading strand synthesis apparatus / Lagging strand synthesis apparatus / DNA helicase / Mcm2-7 complex / Checkpoint control / 染色体DNA複製開始機構 / Mcm2-7蛋白群 / Mcm10蛋白 / S-期チェックポイント / Rad53蛋白 / Xenopus egg in Vitro Replication system / MCM10蛋白 / Cdc7p / Dbf4p複合体 / in vitro 複製系 / Xenopus egg / Sー期チェックポイント / Chromosomal DNA replication / Mcm2-7 protein complex / Mcm10 protein / S-phase checkpoint / Rad53p / Protein kinase / Xenopus egg in vitro replication system
…
More
Except Principal Investigator
DNA複製 / 細胞周期 / サイクリン / がん遺伝子 / 複製蛋白 / 複製起点 / 染色体分配 / 細胞分裂 / ライセンス因子 / DNA修復 / ノックアウトマウス / ゲノム情報 / 癌遺伝子 / 癌抑制遺伝子 / ユビキチン / TGFβ / RV蛋白質 / ^<cdc2>キナーゼ / ゲノム複製 / 複製開始点 / ARS配列 / 複製遺伝子 / 複製酵素 / 組換え遺伝子 / 組換え蛋白 / ホリデー構造 / 核骨格 / 相同組換え / 非相同組換え / 組換えホットスポット / 減数分裂 / 遺伝子組換え / ホットスポット / RAD51 / RecA / がん抑制遺伝子 / DNAポリメラーゼalpha / cdc2キナーゼ / RB蛋白質 / TGFbeta / DNAトランスアクション / 遺伝情報維持 / 複製 / 修復 / 組換え / 転写 / 複製開始蛋白 / チェックポイント / 複製装置 / 複製開始の調節 / SeqA / DnaA / 複製開始 / 複製エラー / ミスマッチ修復 / 酵素ラジカル / フレームシフト / 繰り返し配列 / 酸素ラジカル / 突然変異 / DNA / DNA組換え / DNAポリメラーゼ / 遺伝子 / 自然突然変異 / 遺伝的不安定性 / がん / 遺伝病 / 転写調節 / シグナル分子 / 細胞内物質輸送 / アポトーシス / 転写調節因子 / レチノイン酸 / DNA損傷 / インポーティン / 細胞分化 / SOX / POU / コケイン症候群 / DNA polymerase / ターゲティング / importin / XAB / 先端生命科学 / アジア環太平洋地域 / 分子生物学ネットワーク(A-IMBN) / ゲノミックス / プロテオミックス / 国際共同研究 / プロテオーム / Frontier Life Sciences / Asia and Pacific Rim region / Asia-Pacific Molecular Biology Network / Genomics / Proteomics / International collabolation
Less
Research Projects
(
25
results)
Research Products
(
2
results)
Co-Researchers
(
68
People)
Project Start Year (Newest)
Project Start Year (Oldest)
DNAポリメラーゼεミューテーター変異マウスの構築とその発がん機構の解析
Principal Investigator
Principal Investigator
杉野 明雄
Project Period (FY)
2006
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Review Section
Biological Sciences
Research Institution
Osaka University
DNAポリメラーゼεミューテーター変異マウスの構築とその発がん機構の解析
Principal Investigator
Principal Investigator
杉野 明雄
Project Period (FY)
2005
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Review Section
Biological Sciences
Research Institution
Osaka University
真核生物染色体DNA複製フォークの分子ダイナミズム
Principal Investigator
Principal Investigator
杉野 明雄
Project Period (FY)
2003 – 2006
Research Category
Grant-in-Aid for Scientific Research (S)
Research Field
Molecular biology
Research Institution
Osaka University
個体生命を支える素機構の統合
Principal Investigator
近藤 寿人 (近藤 壽人)
Project Period (FY)
2000 – 2004
Research Category
Grant-in-Aid for COE Research
Research Institution
Osaka University
Development of frontier life science research for prevention and therapy of endemic diseases in Asia and the Pacific Rim Region
Principal Investigator
KOIKE Katsuro
Project Period (FY)
2000 – 2001
Research Category
Grant-in-Aid for Special Purposes
Research Institution
Japanese Foundation for Cancer Research
DNA Replication Apparatus and S-Phase Checkpoint Control
Principal Investigator
Principal Investigator
SUGINO Akio
Project Period (FY)
1999 – 2001
Research Category
Grant-in-Aid for Scientific Research (A)
Research Field
Molecular biology
Research Institution
Osaka University
細胞複製装置:染色体の複製・分配機構
Principal Investigator
平賀 壮太 (平賀 壯太 / 平賀 莊太)
Project Period (FY)
1996 – 2000
Research Category
Grant-in-Aid for Scientific Research on Priority Areas (A)
Research Institution
Kumamoto University
突然変異の分子病態
Principal Investigator
真木 寿治
Project Period (FY)
1996 – 1999
Research Category
Grant-in-Aid for Scientific Research on Priority Areas (A)
Research Institution
Nara Institute of Science and Technology
Molecular Mechanism of Initiation of DNA Replication
Principal Investigator
Principal Investigator
SUGINO Akio
Project Period (FY)
1996 – 1998
Research Category
Grant-in-Aid for international Scientific Research
Research Field
Molecular biology
Research Institution
Osaka University
Molecular Mechanism of Chromosomal DNA Replication Apparatus
Principal Investigator
Principal Investigator
SUGINO Akio
Project Period (FY)
1996 – 1999
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Research Institute for Microbial Diseases, Osaka University
真核生物DNA修復反応におけるDNAポリメラーゼβ及びεの役割
Principal Investigator
Principal Investigator
杉野 明雄
Project Period (FY)
1995
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Osaka University
細胞複製装置:染色体の複製・分配機構
Principal Investigator
平賀 壯太
Project Period (FY)
1995
Research Category
Grant-in-Aid for Co-operative Research (B)
Research Field
Molecular biology
Research Institution
Kumamoto University
EXPRESSION OF EUKARYOTIC DNA REPLICATION PROTEIN COMPLEXS AND THEIR SIMPLE PURIFICATION METHOD
Principal Investigator
Principal Investigator
SUGINO Akio
Project Period (FY)
1995 – 1996
Research Category
Grant-in-Aid for Scientific Research (A)
Research Field
Molecular biology
Research Institution
Osaka University
真核生物DNA修復反応におけるDNAポリメラーゼβ及びεの役割
Principal Investigator
Principal Investigator
杉野 明雄
Project Period (FY)
1994
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Osaka University
DNAトランスアクションと遺伝情報の安定性
Principal Investigator
花岡 文雄
Project Period (FY)
1994
Research Category
Grant-in-Aid for Co-operative Research (B)
Research Field
Cell biology
Research Institution
Osaka University
組換え機構の分子的基礎
Principal Investigator
堀田 康雄
Project Period (FY)
1993
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Nagoya University
細胞周期の制御機構における癌遺伝子、癌抑制遺伝子および関連遺伝子の研究
Principal Investigator
花岡 文雄
Project Period (FY)
1993
Research Category
Grant-in-Aid for Cancer Research
Research Institution
The Institute of Physical and Chemical Research
ヒト染色体DNA複製開始を制御している遺伝子の単離と解析
Principal Investigator
Principal Investigator
杉野 明雄
Project Period (FY)
1993
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Osaka University
ショウジョウバエDNAポリメラーゼεの細胞内での役割
Principal Investigator
Principal Investigator
杉野 明雄
Project Period (FY)
1993
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Osaka University
Molecular biological and genetical study on the mechanism of chromosomal DNA replicaiton in eukaryotes -Yeast as a model-
Principal Investigator
Principal Investigator
SUGINO Akio
Project Period (FY)
1993 – 1995
Research Category
Grant-in-Aid for General Scientific Research (A)
Research Field
Molecular biology
Research Institution
Osaka University
真核細胞染色体複製開始の細胞周期による制御機構の研究
Principal Investigator
Principal Investigator
杉野 明雄
Project Period (FY)
1992 – 1994
Research Category
Grant-in-Aid for international Scientific Research
Research Institution
Osaka University
細胞周期の制御機構における癌遺伝子・癌抑制遺伝子および関連遺伝子の研究
Principal Investigator
花岡 文雄
Project Period (FY)
1992
Research Category
Grant-in-Aid for Cancer Research
Research Institution
The Institute of Physical and Chemical Research
ヒト染色体DNA複製開始を制御している遺伝子の単離と解析
Principal Investigator
Principal Investigator
杉野 明雄
Project Period (FY)
1992
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Osaka University
ゲノム複製開始の制御
Principal Investigator
吉川 寛
Project Period (FY)
1992 – 1994
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Nara Institute of Science and Technology
Osaka University
ショウジョウバエDNAポリメラーゼεの細胞内での役割
Principal Investigator
Principal Investigator
杉野 明雄
Project Period (FY)
1992
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Osaka University
All
2006
2004
All
Journal Article
[Journal Article] Historical view of DNA replication studies, with special reference to Japan.
2006
Author(s)
Sugino, A.
Journal Title
IUBMB Life 58
Pages
: 323-327
Data Source
KAKENHI-PROJECT-15107003
[Journal Article] Distinct roles of DNA polymerases, delta and epsilon at the replication fork in Xenopus egg extracts.
2004
Author(s)
Fukui, T., Waga, S., Sugino, A., et al.
Journal Title
Genes Cells 9
Pages
: 179-191
Data Source
KAKENHI-PROJECT-12CE2007
# of Projects (Dsc)
# of Projects (Asc)
1.
川崎 泰生
(30243257)
# of Collaborated Projects:
6 results
# of Collaborated Products:
0 results
2.
MAKI Hisaji
(20199649)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
3.
YOSHIDA Shonen
(70090420)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
4.
花岡 文雄
(50012670)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
5.
荒木 弘之
(20151160)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
6.
松影 昭夫
(90019571)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
7.
平賀 壯太
(40027321)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
8.
ITO Yoshiaki
(80004612)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
9.
MAKI Satoko
(60212205)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
10.
TSURIMOTO Toshiki
(30163885)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
11.
野瀬 清
(70012747)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
12.
田矢 洋一
(60133641)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
13.
金田 澄子
(60152815)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
14.
井出 利憲
(60012746)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
15.
吉川 寛
(70019876)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
16.
堀内 嵩
(60108644)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
17.
清水 喜久雄
(20162696)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
18.
滝澤 温彦
(60154944)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
19.
岡部 勝
(30089875)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
20.
奥野 友紀子
(00372524)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
21.
JOHNSTON Lel
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
22.
LEEM Sun-hee
(40263313)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
23.
MASAI Hisao
(40229349)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
24.
ITOH Tateo
(40051817)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
25.
SUGIMOTO Katsunori
(90192616)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
26.
OHMORI Haruo
(10127061)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
27.
HIRAGA Shin-ichiro
(90322172)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
28.
KOIKE Katsuro
(30085625)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
29.
ASASHIMA Makoto
(00090564)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
30.
MIYAJIMA Atsushi
(50135232)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
31.
ARAI Ken-ichi
(00012782)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
32.
山口 和男
(00019879)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
33.
堀内 賢介
(70219210)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
34.
今本 文男
(00029761)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
35.
小笠原 直毅
(10110553)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
36.
堀田 康雄
(30190218)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
37.
城石 俊彦
(90171058)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
38.
小林 一三
(30126057)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
39.
大坪 栄一
(10158800)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
40.
小川 英行
(70028207)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
41.
柴田 武彦
(70087550)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
42.
関口 睦夫
(00037342)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
43.
升方 久夫
(00199689)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
44.
柳田 充弘
(80025428)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
45.
岡崎 恒子
(10022584)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
46.
続 輝久
(40155429)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
47.
葛西 宏
(40152615)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
48.
能美 健彦
(30150890)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
49.
中村 健司
(90253533)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
50.
林 健志
(00019671)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
51.
近藤 寿人
(70127083)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
52.
濱田 博司
(00208589)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
53.
田中 亀代次
(80144450)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
54.
辻本 賀英
(70132735)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
55.
米田 悦啓
(80191667)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
56.
関 丘
(40271118)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
57.
和賀 祥
(60222402)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
58.
榎本 武美
(80107383)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
59.
ISHIMI Yukio
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
60.
MORRISON Ala
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
61.
DIFFLEY John
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
62.
CAMPBELL Jud
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
63.
TYE BikーKwoo
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
64.
JOHN.F.X. Diffey
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
65.
LELAND H. Johnston
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
66.
BIK-KWOON Tye
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
67.
JUDITH L. Campbell
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
68.
TYE Bik Kwoo
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
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