Ohtsubo Eiichi 大坪栄一

… Alternative Names

Researcher Number	10158800
Affiliation (Current)	2020: 東京大学, 名誉教授, 名誉教授
Affiliation (based on the past Project Information) *help	2004 – 2005: 東京大学, 分子細胞生物学研究所, 名誉教授 1996 – 2003: 東京大学, 分子細胞生物学研究所, 教授 1993 – 1994: 東京大学, 分子細胞生物学研究所, 教授 1993: 分子細胞生物学研究所, 教授 1986 – 1992: 東京大学, 応用微生物研究所, 教授 … More
Review Section/Research Field	Principal Investigator Biological Sciences / 分子遺伝学・分子生理学 / Molecular biology / 系統・分類 Except Principal Investigator Molecular biology / 分子遺伝学・分子生理学 / 広領域
Keywords	Principal Investigator トランスポゾン / 転移 / 挿入因子 / トランスポゼ-ス / 大腸菌 / 末端逆向き配列 / ゲノム再編 / 接合 / プラスミド / 病原性大腸菌 … More Except Principal Investigator 遺伝暗号 / 反復配列 / アミノアシルtRNA合成酵素 / 減数分裂 / トランスポゾン / 分子進化 / 動く遺伝子 / 突然変異 / 分子適応 / 分泌系内膜構成遺伝子 / コドン / tRNA / アンチコドン / 転写後修飾 / ホットスポット / 非相同組換え / 組換えホットスポット / 大腸菌ゲノムの編制 / 転写・翻訳制御因子 / tRNA遺伝子 / 解糖系酵素遺伝子 / プリン生合成遺伝子 / IS因子とゲノムの再編 / tRNAアイデンティティ- / フレ-ムシフト / 減数分裂期組換え / RecA蛋白質 / シャフロン / 相同組換え / 遺伝子組換え / 遺伝的組換え / DNA複製 / プラスミド / 細菌染色体 / 塩基配列 / 高度反復配列REP / ナンセンス・サプレション / フレームシフト / 大腸菌ゲノム編制 / 転写開始因子 / 低分子RNA10Sa / ヘム合成遺伝子 / IS3挿入因子 / 突然変異体 / 促進因子 / 抑制因子 / SPOmutants / recA,recD / トランスポゼ-ス / 遺伝的組換えの分子機構 / 遺伝子タ-ゲッティング / 組換えのホットスポット / 組換え酵素 / 組換え遺伝子 / 組換え蛋白 / ホリデー構造 / 核骨格 / RAD51 / RecA / 遺伝情報の再編成 / 染色体異常 / レトロトランスポゾン / 免疫グロブリン遺伝子 / 酵母 / 染色体 / コールドスポット / 相同染色体対合 / 体細胞内組換え / DNA組換え / 組換え修復 / RuvBタンパク質 / hjc遺伝子 / SOS反応 / RAD51タンパク質 / DMC1タンパク質 / MRC11タンパク質 / 相同的DNA組換え / RuvABC / Mre11 / Rad54 / DNA複製フォーク / 接合伝達 / 不稔 / 結晶解析 / ブルーム症候群 / ウエルナ-症候群 / 二重鎖切断 / 複製開始領域 / 開始たん白 / DNA-たん白相互作用 / DNA結合たん白 / 核酸コンフォーメーション / 制御DNA領域 / 複製開始蛋白 / 転写制御 / 分子識別 / 遺伝子のターゲッティング / 大腸菌 / 哺乳動物 / 遺伝子の人工的改変 / 改変遺伝子の各種細胞への導入 / キメラ個体の作成 / トランスポゾン転移酵素 / 標的遺伝子破壊 / ホリデ-構造開裂酵素 / DNAヘリカーゼ / 抗体受容体遺伝子再構成 / プラスミドシャフロンのDNA逆位 / 組み換えホットスッポット / 抗原受容体遺伝子再構成 / 相同的組換え / ジャイレース依存の組換え / 遺伝子ターゲッティング / 部位特異的組換え / Genetic recombination / RecA protein / RecA homologues / Rad51 protein / Transposon / Shufflon / Illegitimate recombination / Recombination hot spot / 大腸菌ゲノム / 整列クロ-ン / 大腸菌デ-タベ-ス / 塩基配列決定 / 遺伝子機能解析 / 染色体地図 / 整列クローン / 遺伝情報データベース / ゲノム構造の全体像 / E. coli genome / Ordered clones / E. coli database / Nucleotide sequencing / Functional analysis of genes Less

バクテリアの挿入因子ISによるゲノム再編成Principal Investigator
- Principal Investigator
  
  大坪栄一
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
バクテリアの挿入因子によるゲノム再編の解析Principal Investigator
- Principal Investigator
  
  大坪栄一
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
バクテリアの挿入因子によるゲノム再編の解析Principal Investigator
- Principal Investigator
  
  大坪栄一
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Novel developments on genetic recombination : DNA double-strand break and DNA end-joiningPrincipal Investigator
- Principal Investigator
  
  OHTSUBO Eichi, 池田日出男
- Project Period (FY)
  1998 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
  Kitasato Institute
Mechanisms of transposition and its regulation of bacterial transposable elements (IS and Tn) and their involvement in the genomic rearrangementsPrincipal Investigator
- Principal Investigator
  
  OHTSUBO Eichi
- Project Period (FY)
  1998 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
トランスポゾンの転移組み換えの初期反応の解析Principal Investigator
- Principal Investigator
  
  大坪栄一
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
DNA組換えと組換え修復の普遍的機構
- Principal Investigator
  
  品川日出夫
- Project Period (FY)
  1996 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Osaka University
トランスポゾン転移組換えの初期反応の解析Principal Investigator
- Principal Investigator
  
  大坪栄一
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
Classification of rice strains with use of transposable elementsPrincipal Investigator
- Principal Investigator
  
  OHTSUBO Eiichi
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  系統・分類
- Research Institution
  The university of Tokyo
遺伝子組換えの制御に関する調査研究
- Principal Investigator
  
  堀田康雄
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  Molecular biology
- Research Institution
  Nara Institute of Science and Technology
イネ染色体上に存在する新しいタイプのトランスポゾンの解明Principal Investigator
- Principal Investigator
  
  大坪栄一
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  The University of Tokyo
組換え機構の分子的基礎
- Principal Investigator
  
  堀田康雄
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Nagoya University
接合伝達開始とその制御の分子機構Principal Investigator
- Principal Investigator
  
  大坪栄一
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
遺伝情報の組換え制御に関する調査研究
- Principal Investigator
  
  池田日出男
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  Molecular biology
- Research Institution
  The University of Tokyo
接合伝達開始とその制御の分子機構Principal Investigator
- Principal Investigator
  
  大坪栄一
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
ゲノム編制の全体像
- Principal Investigator
  
  溝渕潔
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
遺伝暗号解読のメカニズム
- Principal Investigator
  
  横山茂之
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
組換え機構の分子的基礎
- Principal Investigator
  
  HOTTA Yasuo
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Nagoya University
生体機能における組換えの基本機構
- Principal Investigator
  
  小川英行
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
Basic Mechanisms of Genetic Recombination
- Principal Investigator
  
  OGAWA Hideyuki
- Project Period (FY)
  1991 – 1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
ゲノム編制の全体像
- Principal Investigator
  
  溝渕潔
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
遺伝暗号解読のメカニズム
- Principal Investigator
  
  横山茂之
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
Property of transposase encoded by transposon Tn3 and its role in the transposition mechanismPrincipal Investigator
- Principal Investigator
  
  OHTSUBO Eiichi
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  分子遺伝学・分子生理学
- Research Institution
  University of Tokyo
トランスポゾンTn3のコ-ドするトランスポゼ-スの性質と転移の分子機構の解明Principal Investigator
- Principal Investigator
  
  大坪栄一
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  分子遺伝学・分子生理学
- Research Institution
  The University of Tokyo
進化学的視野をもつ分子遺伝学的研究
- Principal Investigator
  
  武藤あきら
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Nagoya University
ゲノム編制の全体像
- Principal Investigator
  
  溝渕潔
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
遺伝暗号解読のメカニズム
- Principal Investigator
  
  横山茂之
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
遺伝子の再編とその制御に関する基礎及び応用的研究
- Principal Investigator
  
  池田日出男
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  分子遺伝学・分子生理学
- Research Institution
  The University of Tokyo
性決定因子R100のtra領域の分子遺伝学的解析Principal Investigator
- Principal Investigator
  
  大坪栄一
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
進化学的視野をもつ分子遺伝学的研究
- Principal Investigator
  
  武藤〓
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Nagoya University
"Structural Analysis of the Whole Genome of Escherichia coli"
- Principal Investigator
  
  ISONO Katsumi
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  広領域
- Research Institution
  Kobe University
性決定因子R100のtra領域の分子遺伝学的解析Principal Investigator
- Principal Investigator
  
  大坪栄一
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
進化学的視野をもつ分子遺伝学的研究
- Principal Investigator
  
  武藤〓
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Nagoya University
制御DNA領域の識別
- Principal Investigator
  
  吉川寛
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Osaka University
制御DNA領域の識別
- Principal Investigator
  
  犬塚學
- Project Period (FY)
  1985 – 1987
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  福井医科大学
插入因子IS1の分子レベルに於ける構造と機能の解析Principal Investigator
- Principal Investigator
  
  大坪栄一
- Project Period (FY)
  1983 – 1985
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  分子遺伝学・分子生理学
- Research Institution
  The University of Tokyo

All 2005 2004

All Journal Article

[Journal Article] Two new SINE elements, p-SINE2 and p-SINE3, from rice.2005
- Author(s)
  Xu, J.-H., Osawa, I., Tsuchimoto, S., Ohtsubo, H., Ohtsubo, E.
- Journal Title
  
  Genes Genet.Syst.Genes Genet.Syst. 80
  
  Pages: 161-171
- NAID
  130000062154
- Data Source
  KAKENHI-PROJECT-17019012
[Journal Article] Australian wild rice species Oryza meridionalis consists of annual and perennial ecotype strains.2005
- Author(s)
  Xu, J.-H., Kurata, N., Akimoto, M., Ohtsubo, H., Ohtsubo, E.
- Journal Title
  
  Genes Genet.Syst. (印刷中)
- Data Source
  KAKENHI-PROJECT-16013211
[Journal Article] Identification and characterization of Australian wild rice strains of Oryza meridionalis and Oryza rufipogon by SINE insertion polymorphism.2005
- Author(s)
  Xu, J.-H., Kurata, N., Akimoto, M., Ohtsubo, H., Ohtsubo, E.
- Journal Title
  
  Genes Genet.Syst. 80
  
  Pages: 129-134
- NAID
  130000062166
- Data Source
  KAKENHI-PROJECT-17019012
[Journal Article] The genome sequence of Clostridium botulinum type C neurotoxin-converting phage and the molecular mechanisms of unstable lysogeny.2005
- Author(s)
  Sakaguchi, Y., Hayashi, T., Kurokawa, K., Nakayama, K., Oshima, K., Fujinaga Y., Ohnishi, M., Ohtsubo, E., Hattori, M., Ogma, K.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA. in press
- Data Source
  KAKENHI-PROJECT-17019012
[Journal Article] Intermediate molecules generated by transposase in the pathways of transposition of bacterial insertion element IS32004
- Author(s)
  Ohtsubo, E.Minematsu, H.Tsuchida, K., Ohtsubo, H., Sekine, Y.
- Journal Title
  
  Adv.Biophys. 38
  
  Pages: 125-139
- Data Source
  KAKENHI-PROJECT-16013211
[Journal Article] Rice retroposon p-SINE1 and origin of the cultivated rice.2004
- Author(s)
  Ohtsubo, H., Cheng, C., Tsuchimoto, S., Ohtsubo E.
- Journal Title
  
  Breed.Sci. 58
  
  Pages: 1-11
- NAID
  110001803259
- Data Source
  KAKENHI-PROJECT-16013211
[Journal Article] Involvement of two domains with helix-turn-helix and zinc finger motifs in the binding of IS1 transposase to terminal inverted repeats.2004
- Author(s)
  Ohta, S., Yoshimura, E., Ohtsubo, E.
- Journal Title
  
  Mol.Microbiol. 53
  
  Pages: 193-202
- Data Source
  KAKENHI-PROJECT-16013211

1. OGAWA Hideyuki (70028207)

# of Collaborated Projects: 8 results

# of Collaborated Products: 0 results
2. HOTTA Yasuo (30190218)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
3. IKEDA Hideo (10012775)

# of Collaborated Projects: 7 results

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4. SHIBATA Takehiko (70087550)

# of Collaborated Projects: 5 results

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5. 中村義一 (40114590)

# of Collaborated Projects: 5 results

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6. INOKUCHI Hachiro (20028195)

# of Collaborated Projects: 4 results

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7. SHIROISHI Tosihiko (90171058)

# of Collaborated Projects: 4 results

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8. 武藤あきら (80034635)

# of Collaborated Projects: 3 results

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9. SKIGUCHI Mutsuo (00037342)

# of Collaborated Projects: 3 results

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10. OHTSOBO Hisako (20158801)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
11. 池村淑道 (50025475)

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12. 谷藤茂行 (50000774)

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13. 西郷薫 (50136454)

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14. 水野重樹 (90112903)

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16. 伊藤維昭 (90027334)

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17. 中沢淳 (90025594)

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23. 吉川寛 (70019876)

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25. 柳田充弘 (80025428)

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26. 小川智子 (80028208)

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27. 土本卓 (60212057)

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29. 伊藤建夫 (40051817)

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30. KOGA Akiniko (80192574)

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31. IIDA Shigeru (30012777)

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32. SEKINE Yasuhiko (80222074)

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33. ISONO Katsumi (70011640)

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34. NAKATA Atsuo (80029769)

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35. ISIHAMA Akira (80019869)

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36. YURA Takashi (20027311)

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37. 外村辨一郎 (20026545)

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38. 杉野明雄 (90231737)

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39. 鈴木義昭 (50132733)

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40. 品川日出夫 (40029799)

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41. 榎本武美 (80107383)

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42. 森田隆 (70150349)

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43. 堀内嵩 (60108644)

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44. 武田俊一 (60188191)

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46. 山口和男 (00019879)

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47. 宍戸和夫 (40087549)

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54. 志村令郎 (60025426)

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Ohtsubo Eiichi 大坪 栄一

OHTSUBO Eiichi 大坪 栄一

大坪 英一

Research Projects

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バクテリアの挿入因子ISによるゲノム再編成Principal Investigator

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バクテリアの挿入因子によるゲノム再編の解析Principal Investigator

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バクテリアの挿入因子によるゲノム再編の解析Principal Investigator

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Novel developments on genetic recombination : DNA double-strand break and DNA end-joiningPrincipal Investigator

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Mechanisms of transposition and its regulation of bacterial transposable elements (IS and Tn) and their involvement in the genomic rearrangementsPrincipal Investigator

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トランスポゾンの転移組み換えの初期反応の解析Principal Investigator

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トランスポゾン転移組換えの初期反応の解析Principal Investigator

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Classification of rice strains with use of transposable elementsPrincipal Investigator

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イネ染色体上に存在する新しいタイプのトランスポゾンの解明Principal Investigator

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接合伝達開始とその制御の分子機構Principal Investigator

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Ohtsubo Eiichi 大坪栄一

OHTSUBO Eiichi 大坪栄一

大坪英一