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Oishi Michio  大石 道夫

ORCIDConnect your ORCID iD *help
… Alternative Names

大石 道夫  オオイシ ミチオ

OISHI Michio  大石 道夫

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Researcher Number 00126004
Affiliation (Current) 2022: 公益財団法人かずさDNA研究所, その他部局等, 理事長
Affiliation (based on the past Project Information) *help 1996: 通産省工業技術院/生計工学工業技術研究所, 所長
1993 – 1994: Institute of Molecular and Cellular Bioscience, Professor, 分子細胞生物学研究所, 教授
1993: 分子細胞生物学研究所, 教授
1992: 東京大学応用微生物学研究所, 教授
1992: 東京大学応用微生物研究所, 教授 … More
1986 – 1992: 東京大学, 応用微生物研究所, 教授
1986: 東大, 応用微生物研究所, 教授
1985: 東京大学, 応微研, 教授 Less
Review Section/Research Field
Principal Investigator
分子遺伝学・分子生理学
Except Principal Investigator
分子遺伝学・分子生理学 / 応用生物化学・栄養化学 / Cell biology
Keywords
Principal Investigator
細胞分化 / 分化誘導 / プラスミド / フレンド細胞 / 白血病細胞 / 分化 / 脱癌化 / 細胞融合 / DIF-I / DIF-II … More / DIF-III / タンパク質 / リン酸化 / 発生 / 遺伝子発現 / クローニング / リン酸化チロシンの脱リン酸化 / ハ-ビマイシンA / ゲニステイン / ST638 / 脱リン酸化 / ゲノムDNA / 生態細胞形成 / エンハンサ- / 中胚葉分化 / activin A / 背軸決定 / 細胞質性因子 / DNA / トランスポゾン / 細胞質融合 / マウス・フレンド細胞 / チロシンキナーゼ阻害剤herbmycin A,genistein,ST638 / Differntiation / cell fusion / erythroid cells / 胚性腫瘍細胞 / リン酸化タンパク質 / herbimycin A / genistein / ST 638 / 分化決定因子(commitment factor) / Differentiation / Embryonal / Phosphorylation / erythroid … More
Except Principal Investigator
細胞分化 / 癌遺伝子 / cーmyc / cーmyb / 細胞周期 / 転写制御 / 情報伝達 / 食品成分 / 小腸上皮細胞 / 多細胞体制の形成 / 組織・器官の再生 / 形態形成因子 / 分化誘導因子 / 遺伝子発現制御 / 形態形成遺伝子 / 7番染色体 / 放射線雑種細胞 / 細胞老化遺伝子 / 動原体 / 動物培養細胞 / 軟骨細胞 / 赤血球 / プログラミング / チロシンリン酸化 / 脂肪細胞 / EIA遺伝子 / 部位特異的組換え / c-myc遺伝子 / 不死化遺伝子 / トランスポゾン / 発生プログラム / 不死化細胞株 / RFLP解析 / 微小核細胞融合法 / D群不死化細胞株 / シグナル伝達系 / トポイソメラーゼ / 細胞老化 / 遺伝子マッピング / 不死化 / 不死化細胞 / 分化の決定 / マウス赤白血病細胞 / 遺伝子導入 / 染色体 / スーパーコイル / 複製開始 / ビタミン類 / 発癌プロモーション / ras / 細胞増殖 / 発癌プロモ-ション / 転写 / 形態形成制御因子 / 細胞成長因子 / 分化調節因子 / 細胞接着 / 細胞認識 / パタ-ン形成 / 分化形質発現 / 分化形質転換 / RNAポリメラ-ゼ / c‐mos遺伝子 / c‐myc産物 / CDC28キナ-ゼ / 有性生殖 / 抗原受容体遺伝子 / クラススイッチ組換え / DNA逆位 / DNAトポイソメラ-ゼ / 遺伝子の標的組込み / 家族性アミロイド-シス / TーDNA組込み / D因子 / I因子 / Nm23 / NDPキナーゼ / リン酸化チロシン蛋白質 / ガングリオシド / ltk蛋白質 / 受容体発現異常 / DNAポリメラーゼα / RNAポリメラーゼ / cdc2遺伝子 / c-Myc蛋白質 / Mos蛋白質 / MAPキナーゼ / DNAポリメラーゼalpha / リボゾーム修飾因子 / CCG1遺伝子 / PKC / 減数分裂 / C^-myc遺伝子 / C^-mos産物 / RCCI遺伝子 / SGVIキナーゼ / cAMP / 免疫グロブリン遺伝子 / T細胞抗原レセプター遺伝子 / 非相同組換え / 標的遺伝子組換え / T-DNA / 遺伝子脆弱部位 / FISH解析 / 遺伝子クローニング / 7番目染色体 / cGMP_-依存プロテインキナーゼ / ゲノムサブトラクション / LOH / がん抑制遺伝子 / 発がん / 腎がん / マイクロサテライト / 多型 / 組換えDNA実験 / 形質発現 / 遺伝子の構造 / 生体機能 / 遺伝子 / 資源植物 / 資源動物 / 有用遺伝子 / 染色体構築 / 凝縮-脱疑縮 / 機能領域 / 活性染色体 / 遺伝的組換え / 遺伝子のターゲッティング / 大腸菌 / 哺乳動物 / 遺伝子の人工的改変 / 改変遺伝子の各種細胞への導入 / キメラ個体の作成 / 多細胞体制 / 形態形成 / 修復再生 / 形態形成調節因子 / 遺伝子発現調節因子 / 染色体の構築 / 超ねじれ化 / 染色体凝縮 / 動物細胞培養 / ビタミンA / 発ガンプロモーション / 細胞不死化 / L1反復配列 / 相補性群 / 分裂停止遺伝子 / 老化遺伝子 / 正常線維芽細胞 / 微少核細胞融合法 / 染色体導入 / 染色体マッピング / アンチセンスcDNAライブラリ- / Senescence / Immortalization / Gene / Chromosome 7 / Signal transduction / Gene mapping / 三重鎖DNA / 結合タンパク質 / ポリプリン・ポリピリミジン / ビオチン / 反復配列 / クローニング / ポリプリン・ポリピリジン / triplex DNA / binding protein / polypurine. polypyrimidine / biotin / repetitive sequence / cloning / 遺伝子クローン化 / 細部老化 / 細部不死化 / cGMP-依存プロテインキナーゼ / SENESCENCE / IMMORTALIZATION / GENE / CHROMOSOME 7 / GENE MAPPING / RADIATION HYBRID Less
  • Research Projects

    (39 results)
  • Co-Researchers

    (66 People)
  •  新しいゲノム・サブトラクション法を用いたがん抑制遺伝子の探索

    • Principal Investigator
      KIYAMA Ryoiti
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  がん細胞の不死化遺伝子の同定

    • Principal Investigator
      鮎沢 大
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  CHARACTERIZATION OF SENESCENCE GENES IN HUMAN CELLS

    • Principal Investigator
      AYUSAWA Dai
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cell biology
    • Research Institution
      KIHARA INSTITUTE FOR BIOLOGICAL RESEARCH
      The University of Tokyo
  •  生理機能の発現と組換え機構

    • Principal Investigator
      池田 日出男
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  ヒト細胞における不死化遺伝子の解析

    • Principal Investigator
      鮎沢 大
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  正常造血幹細胞,造血因子と造血器腫瘍との比較と相互関係

    • Principal Investigator
      穂積 本男
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Research Institute for Clinical Oncology, Saitama Cancer Center
  •  細胞複製制御の遺伝子発現

    • Principal Investigator
      花岡 文雄
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
      The Institute of Physical and Chemical Research
  •  発生プログラムの発現とその調節

    • Principal Investigator
      江口 吾朗
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Okazaki National Research Institutes
  •  Biological significance of the human protein that specifically binds to triplex DNA

    • Principal Investigator
      KIYAMA Ryoiti
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      分子遺伝学・分子生理学
    • Research Institution
      The University of Tokyo
  •  細胞分化のプログラミングと癌遺伝子

    • Principal Investigator
      帯刀 益夫
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Tohoku University
  •  分化の調節性と形態を誘導する因子Principal Investigator

    • Principal Investigator
      大石 道夫
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  細胞複製制御の遺伝子発現

    • Principal Investigator
      花岡 文雄
    • Project Period (FY)
      1991 – 1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The Institute of Physical and Chemical Research
  •  生理機能の発現と組換え機構

    • Principal Investigator
      池田 日出男
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  Identification of a growth-suppressing gene in normal human fibroblasts and mouse brain

    • Principal Investigator
      AYUSAWA Dai
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      分子遺伝学・分子生理学
    • Research Institution
      Institute of Molecular and Cellular Biosciences
  •  食品成分による細胞分化誘導の機作

    • Principal Investigator
      杉本 悦郎
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  分化の調節性と形態を誘導する因子Principal Investigator

    • Principal Investigator
      大石 道夫
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  発生プログラムの発現とその調節

    • Principal Investigator
      江口 吾朗
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Okazaki National Research Institutes
  •  細胞分化のプログラミングと癌遺伝子

    • Principal Investigator
      帯刀 益夫
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Tohoku University
  •  マウス白血病細胞分化の分子機構Principal Investigator

    • Principal Investigator
      大石 道夫
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  食品成分による細胞分化誘導の機作

    • Principal Investigator
      杉本 悦郎
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  分化の調節性と形態を誘導する因子Principal Investigator

    • Principal Investigator
      大石 道夫
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  発生プログラムの発現とその調節

    • Principal Investigator
      江口 吾朗
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Okazaki National Research Institutes
  •  細胞分化のプログラミングと癌遺伝子

    • Principal Investigator
      帯刀 益夫
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Tohoku University
  •  発生プログラムの発現とその調節

    • Principal Investigator
      江口 吾朗
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Okazaki National Research Institutes
  •  マウス白血病細胞分化の分子機構Principal Investigator

    • Principal Investigator
      大石 道夫
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  遺伝子の再編とその制御に関する基礎及び応用的研究

    • Principal Investigator
      池田 日出男
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      分子遺伝学・分子生理学
    • Research Institution
      The University of Tokyo
  •  発生プログラムの発現とその調節

    • Principal Investigator
      江口 吾朗
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Institution
      Okazaki National Research Institutes
  •  食品成分による細胞分化誘導の機作

    • Principal Investigator
      杉本 悦郎
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  Studies on intracellular factors involved in cellular differentiation of mouse and human cells.Principal Investigator

    • Principal Investigator
      OISHI Michio
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      分子遺伝学・分子生理学
    • Research Institution
      Inst. of Applied Microbiol. University of Tokyo
  •  染色体の機能領域

    • Principal Investigator
      竹家 達夫
    • Project Period (FY)
      1987 – 1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  マウス白血病細胞分化の分子機構Principal Investigator

    • Principal Investigator
      大石 道夫
    • Project Period (FY)
      1987 – 1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  資源真核生物の有用遺伝子の解析と利用

    • Principal Investigator
      旭 正
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      応用生物化学・栄養化学
    • Research Institution
      Nagoya University
  •  染色体の機能領域

    • Principal Investigator
      竹家 達夫
    • Project Period (FY)
      1987 – 1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  染色体の機能領域

    • Principal Investigator
      竹家 達夫
    • Project Period (FY)
      1987 – 1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  マウス白血病細胞の脱癌化の分子機構Principal Investigator

    • Principal Investigator
      大石 道夫
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      The University of Tokyo
  •  Molecular mechanism of cell differentiation in mammalian cells.Principal Investigator

    • Principal Investigator
      OISHI Michio
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      分子遺伝学・分子生理学
    • Research Institution
      University of Tokyo
  •  DNAの染色体への組みこみと転移Principal Investigator

    • Principal Investigator
      大石 道夫
    • Project Period (FY)
      1985
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      The University of Tokyo
  •  マウス白血球細胞の脱癌化の分子機構Principal Investigator

    • Principal Investigator
      大石 道夫
    • Project Period (FY)
      1985
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      The University of Tokyo
  •  組換えDNAの発現と生体機能

    • Principal Investigator
      高木 康敬
    • Project Period (FY)
      1983 – 1986
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      Fujita Health University
  • 1.  岡田 益吉 (60015534)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 2.  AYUSAWA Dai (00142109)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 3.  NSHIMORI Katsuhiko (10164609)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 4.  佐藤 矩行 (30025481)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 5.  江口 吾朗 (80022581)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 6.  竹市 雅俊 (00025454)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 7.  NOMURA Shintaro (80159087)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 8.  藤沢 肇 (60079689)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 9.  帯刀 益夫 (10099971)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 10.  水野 重樹 (90112903)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 11.  WATANABE Toshio (60201208)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 12.  佐々木 隆造 (60077378)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 13.  野田 亮 (30146708)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 14.  石井 俊輔 (00124785)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 15.  竹家 達夫 (60112330)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 16.  丹羽 修身 (70144318)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 17.  広瀬 進 (90022730)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 18.  杉本 悦郎 (50026522)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 19.  鈴木 不二男 (40028717)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 20.  小清水 弘一 (90026518)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 21.  津田 正明 (80132736)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 22.  近藤 寿人 (70127083)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 23.  池田 日出男 (10012775)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 24.  島田 和典 (40037354)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 25.  小田 鈎一郎 (40012736)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 26.  KIYAMA Ryoiti (00240739)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 27.  本間 良夫 (70142114)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 28.  井川 洋二 (40085618)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 29.  花岡 文雄 (50012670)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 30.  山本 正幸 (40114706)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 31.  小池 克郎 (30085625)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 32.  石浜 明 (80019869)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 33.  駒野 照弥 (00087131)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 34.  川市 正史 (00195041)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 35.  西本 毅治 (10037426)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 36.  菊池 韶彦
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 37.  林 健志 (00019671)
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  • 38.  川上 敏明 (60143418)
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  • 39.  小笠原 直毅 (10110553)
    # of Collaborated Projects: 1 results
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  • 40.  高木 信夫 (20001852)
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  • 41.  田坂 昌生 (90179680)
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  • 42.  山名 清隆 (20037162)
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  • 43.  浅島 誠 (00090564)
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  • 44.  松原 謙一 (20037394)
    # of Collaborated Projects: 1 results
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  • 45.  山岸 秀夫 (90025429)
    # of Collaborated Projects: 1 results
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  • 46.  穂積 本男 (50113478)
    # of Collaborated Projects: 1 results
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  • 47.  白川 茂 (20026850)
    # of Collaborated Projects: 1 results
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  • 48.  平井 久丸 (90181130)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 49.  斎藤 政樹 (60012762)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 50.  小林 泰夫 (10013319)
    # of Collaborated Projects: 1 results
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  • 51.  難波 正義 (80069004)
    # of Collaborated Projects: 1 results
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  • 52.  小山 秀機 (40085626)
    # of Collaborated Projects: 1 results
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  • 53.  高木 康敬 (50037313)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 54.  榊 佳之 (10112327)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 55.  中沢 淳 (90025594)
    # of Collaborated Projects: 1 results
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  • 56.  関口 睦夫 (00037342)
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  • 57.  旭 正 (10023392)
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  • 58.  杉山 達夫 (50023453)
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  • 59.  駒野 徹 (30026413)
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  • 60.  赤澤 尭 (20023400)
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  • 61.  大坪 英一 (10158800)
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  • 62.  柴田 武彦 (70087550)
    # of Collaborated Projects: 1 results
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  • 63.  小川 英行 (70028207)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 64.  渡辺 憲二 (00079691)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 65.  井出 利憲 (60012746)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 66.  菊地 韶彦
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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