WATANABE Toshio 渡邊利雄

… Alternative Names

渡辺利雄ワタナベトシオ

渡邉利雄ワタナベトシオ

渡邊利雄ワタナベトシオ

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Researcher Number	60201208
Other IDs
Affiliation (based on the past Project Information) *help	2012 – 2022: 奈良女子大学, 自然科学系, 教授 2015 – 2016: 奈良女子大学, 大学院人間文化研究科, 教授 2006 – 2011: 奈良女子大学, 大学院・人間文化研究科, 教授 2009: Nara Women's University, 人間文化研究科, 教授 2003 – 2004: 東北大学, 加齢医学研究所, 助教授 … More 2000 – 2001: 東北大学, 加齢医学研究所, 助教授 1996 – 1998: 東北大学, 加齢医学研究所, 助教授 1990 – 1991: 東京大学, 応用微生物学研究所, 助手 1988 – 1989: 東京大学, 応用微生物研究所, 助手 Less
Review Section/Research Field	Principal Investigator Biological Sciences / Functional biochemistry / Basic Section 43030:Functional biochemistry-related / Cell biology / General medical chemistry Except Principal Investigator Immunology / Biophysics / Tumor biology / 分子遺伝学・分子生理学 / Developmental biology … More / Functional biochemistry / Tumor biology / Pathological medical chemistry / Hematology Less
Keywords	Principal Investigator SMAP1 / ARF / 細胞内小胞輸送 / Runx1 / 血管新生 / 転写因子 / SMAP2 / Arf1 / 小胞輸送 / 二重欠損マウス … More / 細胞骨格 / KOマウス / リンパ球 / Filamin / 血管 / 生殖細胞 / Tgマウス / チロシンホスファターゼ / 血球発生 / AGM領域 / 造血発生 / AML1 / c-myb / 生理機能 / 個体レベル / 骨髄移植 / 活性化型K-Ras / PP6 / 脱リン酸化酵素 / 神経細胞分化 / 胎児肝臓造血 / オートファジー / 恒常活性化型K-Ras / 脱リン酸化酵素PP6 / 運動機能障害 / 低分子量Gタンパク質 / 膜輸送と輸送タンパク質 / 神経変性疾患 / 神経異常 / Arf6 / 小胞輸送機構 / BMPシグナル亢進 / 細胞増殖遅延 / 神経特異的欠損 / transcription factor / immunohistochemistry / chimeric gene / acute myeloid leukemia / PEBP2beta / stress fiber / cytoskeleton / muscle development / 免疫組織化学 / キメラ遺伝子 / 急性骨髄性白血病 / PEBP2β / ストレス・ファイバー / 筋分化 / アルツハイマー症 / 核外排出配列NES / CALM-AF10 / CALM / 二重欠損 / ストローマ細胞 / ARFGAP / マウス / 遺伝子破壊 / 細胞外環境 / Arf GAP / TGN / 精子形態形成 / 不妊 / SMAP / Gサイクル / ARF GAP / 先体形成 / 小胞融合 / 精子形成 / GTPse / GAP / Arf / メンブレントラフィック / ARF6 GAP / 再生医学 / 転写制御 / 造血幹細胞 / GATA-3 / 胸腺細胞分化 / Th2 / Th1 / Runx3 / 細胞骨格制御タンパク質 / 癌関連遺伝子 / 血病染色体転座 / 血管内皮細胞 / AML1転写因子 / RUNX / 遺伝子破壊マウス / がん遺伝子 / 遺伝子ターゲティング … More Except Principal Investigator 癌 / mTORC1 / AML1 / runt / SHP-2 / SHPS-1 / DIF-III / DIF-II / DIF-I / ダイナミクス / 細胞内シグナル伝達 / 抗ウイルス自然免疫 / ミトコンドリア / がん / がん関連分子 / 細胞分裂 / 中心体 / BRCA1 / 造血幹細胞 / ガングリオシド / cーmyc遺伝子 / フレンド白血病細胞 / 分化誘導因子 / 白血病細胞 / 分化誘導 / X線結晶構造解析 / プロヒビチン / RNAウイルス / 自然免疫 / 高次機能 / 分子基盤解析 / Arfファミリー / マスト細胞分化 / 小胞輸送 / シグナル伝達 / PI3K / マスト細胞 / 遺伝子改変動物 / ゲノム安定性維持 / ｍTORC1 / 樹状細胞 / サイトカイン / mTOR / erythroid / Phosphorylation / Embryonal / Differentiation / 分化決定因子(commitment factor) / ST 638 / genistein / herbimycin A / 分化 / リン酸化タンパク質 / 胚性腫瘍細胞 / PEBP2beta / T lymphocytes / acute myeloid leukemia / hematopoietic stem cell / transcription factor / アポトーシス / 細胞骨格 / キメラ遺伝子 / CBFβ / PEBP2β / AMLI / Tリンパ球 / 急性骨髄性白血病 / 転写因子 / B cell antigen receptor / Tautomycin / Tyrosine protein phosphatase / threonine protein phosphatase / Serine / Protein phosphatase / Signal transduction / オカダ酸 / アルツハイマー病 / 長期増強 / CD45 / ノジュラリン / B細胞抗原受容体 / トウトマイシン / チロシンホスファターゼ / トレオニンホスファターゼ / セリン / プロテインホスファターゼ / 細胞内情報伝達 / チロシンキナーゼ阻害剤herbmycin A,genistein,ST638 / 酵素機能 / 形態調節 / 分子機構 / 家族性乳癌 / 家族性乳がん / 2重基質ボスファターゼ / 2重基質ホスファターゼ / ２重基質ホスファターゼ / ホスファターゼ / KIF3 / キネシンモーター / 分子腫瘍学 / PML / 細胞分化 / GATA / PU.1 / MOZ / 転写制御 / 白血病 / 幹細胞 / プロティンキナ-ゼC / 幹細胞性白血病 / ltk遺伝子 / チロシンキナ-ゼ / プロテインキナ-ゼC / 染色体相互転座 / 受容体遺伝子 / 細胞内分化因子 / リン酸化 / タンパク質 Less

Elucidation of physiological functions of serine threonine phosphatase PP6Principal Investigator
- Principal Investigator
  
  Watanabe Toshio
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Nara Women's University
Mechanism of mitochondrial dynamics and its physiological relevance
- Principal Investigator
  
  Koshiba Takumi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biophysics
- Research Institution
  Fukuoka University
  Kyushu University
Elucidation of regulatory mechanism to maintain genome stability by novel BRCA1-interacting molecules and development of cancer therapy
- Principal Investigator
  
  CHIBA Natsuko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor biology
- Research Institution
  Tohoku University
Examination of involvement of vesicle transport mechanism in neurodegenerative disease using tissue specific gene deletion methodPrincipal Investigator
- Principal Investigator
  
  Watanabe Toshio
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Nara Women's University
Molecular dissection of mast cell function by using newly generated mast cell lineage specific Cre expressing mice
- Principal Investigator
  
  MATSUDA Satoshi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Immunology
- Research Institution
  Kansai Medical University
Mitochondrial dynamics in mammals and its molecular mechanism
- Principal Investigator
  
  Koshiba Takumi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biophysics
- Research Institution
  Kyushu University
The role of mTORC1 in dendritic cells in adaptive immune response
- Principal Investigator
  
  OHTANI Masashi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Toho University
  Tokyo University of Science
Function of the novel tumor suppressor in cell division and carcinogenesis
- Principal Investigator
  
  Chiba Natsuko
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor biology
- Research Institution
  Tohoku University
Figure of true clathrin-dependent intracellular vesicle transportPrincipal Investigator
- Principal Investigator
  
  WATANABE Toshio
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Nara Women's University
Regulation of KIF3 motor by dephosphorylation
- Principal Investigator
  
  SHIMA Hiroshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Miyagi Cancer Center Research Institute
小胞形成制御因子SMAP1,2は細胞外環境の生理機能にどう影響するかPrincipal Investigator
- Principal Investigator
  
  渡邊利雄
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nara Women's University
Study for regulatory mechanism of normal and leukemic stem cells through transcription factors
- Principal Investigator
  
  KITABAYASHI Issay
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
新規ARF GAPによるARF Gサイクル制御と生理機能の解明Principal Investigator
- Principal Investigator
  
  渡邊利雄
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nara Women's University
転写因子AML1によるT細胞のTh1/Th2系列への振り分け制御機構の解明Principal Investigator
- Principal Investigator
  
  渡邊利雄
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
転写因子AML1とc-mybとによる造血幹細胞の発生と成立のメカニズムPrincipal Investigator
- Principal Investigator
  
  渡邉利雄 (渡邊利雄)
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
円頭精子症候群の新規原因遺伝子の解析とその修飾遺伝子群を探る試みPrincipal Investigator
- Principal Investigator
  
  渡邉利雄 (渡邊利雄)
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  Tohoku University
転写因子とチロシンホスファターゼから探る造血発生と血管新生制御の分子機構Principal Investigator
- Principal Investigator
  
  渡邊利雄
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
転写因子AML1とチロシンホスファターゼPTPβ2から探る血管新生制御の分子機構Principal Investigator
- Principal Investigator
  
  渡邊利雄
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
AML1による胎児期血管新生、造血発生制御の分子機構の解明Principal Investigator
- Principal Investigator
  
  渡邊利雄
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
c-myb,PEBP2欠損マウスのAGM領域での造血発生の変化とその機構の解析Principal Investigator
- Principal Investigator
  
  渡邊利雄
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
Functions of the runt gene family in development
- Principal Investigator
  
  SATAKE Masanobu
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  Developmental biology
- Research Institution
  Institute of Development, Aging and Cancer, Tohoku University
Functions of the PEBP2beta protooncogene product in muscle cell differentiation.Principal Investigator
- Principal Investigator
  
  WATANABE Toshio
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  Institute of Development, Aging and Cancer, Tohoku University
Physiological significance of protein phosphatases on cellular signal transduction
- Principal Investigator
  
  TAKEDA Masao
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional biochemistry
- Research Institution
  HIROSHIMA UNIVERSITY
正常造血幹細胞,造血因子と造血器腫瘍との比較と相互関係
- Principal Investigator
  
  穂積本男
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Research Institute for Clinical Oncology, Saitama Cancer Center
正常造血幹細胞,造血因子と造血器腫瘍との比較と相互関係
- Principal Investigator
  
  穂積本男
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Research Institute for Clinical Oncology, Saitama Cancer Center
マウス白血病細胞分化の分子機構
- Principal Investigator
  
  OISHI Michio
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
マウス白血病細胞分化の分子機構
- Principal Investigator
  
  大石道夫
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
Studies on intracellular factors involved in cellular differentiation of mouse and human cells.
- Principal Investigator
  
  OISHI Michio
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  分子遺伝学・分子生理学
- Research Institution
  Inst. of Applied Microbiol. University of Tokyo

[Book] ADP-ribosylation factor 1. Encyclopedia of Signaling Molecules, 2nd Edition2018
- Author(s)
  Toshio Watanabe and Mami Sumiyoshi.
- Total Pages
  6060
- Publisher
  Springer International Publishing AG 2012
- ISBN
  9781493967995
- Data Source
  KAKENHI-PROJECT-16K07296
[Book] Encyclopedia of Signaling Molecules, 2nd Edition2018
- Author(s)
  Toshio Watanabe and Mami Sumiyoshi
- Total Pages
  6060
- Publisher
  Springer International Publishing AG
- ISBN
  9783319671987
- Data Source
  KAKENHI-PROJECT-16K07296
[Book] 史上最強図解　これならわかる！分子生物学最2013
- Author(s)
  渡邊利雄
- Total Pages
  296
- Publisher
  ナツメ社
- Data Source
  KAKENHI-PROJECT-24570159
[Journal Article] PP6 deficiency in mice with KRAS mutation and Trp53 loss promotes early death by PDAC with cachexia-like features.2022
- Author(s)
  Fukui K, Nomura M, Kishimoto K, Tanuma N, Kurosawa K, Kanazawa K, Kato H, Sato T, Miura S, Miura K, Sato I, Tsuji H, Yamashita Y, Tamai K, Watanabe T, Yasuda J, Tanaka T, Satoh K, Furukawa T, Jingu K, Shima H.
- Journal Title
  
  Cancer Sci.
  
  Volume: 印刷中 Issue: 5 Pages: 1613-1624
- DOI
  10.1111/cas.15315
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09469, KAKENHI-PROJECT-20K06545, KAKENHI-PROJECT-21K19420, KAKENHI-PROJECT-21K19748, KAKENHI-PROJECT-21K07111, KAKENHI-PROJECT-20K07436, KAKENHI-PROJECT-21K15425, KAKENHI-PROJECT-21K16852
[Journal Article] Arf1 facilitates mast cell proliferation via the mTORC1 pathway2022
- Author(s)
  Kotani Yui、Sumiyoshi Mami、Sasada Megumi、Watanabe Toshio、Matsuda Satoshi
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 22297-22297
- DOI
  10.1038/s41598-022-26925-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03776, KAKENHI-PROJECT-20K06545, KAKENHI-PROJECT-20K07555, KAKENHI-PROJECT-21K15474
[Journal Article] Ppp6c deficiency accelerates K-rasG12D -induced tongue carcinogenesis.2021
- Author(s)
  Kishimoto K, Kanazawa K, Nomura M, Tanaka T, Shigemoto-Kuroda T, Fukui K, Miura K, Kurosawa K, Kawai M, Kato H, Terasaki K, Sakamoto Y, Yamashita Y, Sato I, Tanuma N, Tamai K, Kitabayashi I, Matsuura K, Watanabe T, Yasuda J, Tsuji H, Shima H.
- Journal Title
  
  Cancer Med.
  
  Volume: 10(13) Issue: 13 Pages: 4451-4464
- DOI
  10.1002/cam4.3962
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09109, KAKENHI-PROJECT-20K17365, KAKENHI-PROJECT-20K06545, KAKENHI-PROJECT-20K07436, KAKENHI-PROJECT-21K19420, KAKENHI-PROJECT-21K19748, KAKENHI-PROJECT-21K15425
[Journal Article] Ppp6c haploinsufficiency accelerates UV-induced BRAF(V600E)-initiated melanomagenesis.2021
- Author(s)
  Kanazawa K, Kishimoto K, Nomura M, Kurosawa K, Kato H, Inoue Y, Miura K, Fukui K, Yamashita Y, Sato I, Tsuji H, Watanabe T, Tanaka T, Yasuda J, Tanuma N, Shima H
- Journal Title
  
  Cancer Sci.
  
  Volume: in press Issue: 6 Pages: 2233-2244
- DOI
  10.1111/cas.14895
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09469, KAKENHI-PROJECT-19K18757, KAKENHI-PROJECT-20K17365, KAKENHI-PROJECT-20K06545, KAKENHI-PROJECT-20K07436, KAKENHI-PROJECT-21K15425
[Journal Article] Autophagy regulates levels of tumor suppressor enzyme protein phosphatase 6.2020
- Author(s)
  Nobuyuki Fujiwara, Shusaku Shibutani, Yusuke Sakai, Toshio Watanabe, Issei Kitabayashi, Hiroko Oshima, Masanobu Oshima, Hisashi Hoshida, Rinji Akada, Tatsuya Usui, Takashi Ohama*, Koichi Sato.
- Journal Title
  
  Cancer Science
  
  Volume: 111 Issue: 12 Pages: 4371-4380
- DOI
  10.1111/cas.14662
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06545, KAKENHI-PROJECT-19H03498, KAKENHI-PROJECT-20H03151, KAKENHI-PROJECT-18K06018, KAKENHI-PROJECT-18K16364
[Journal Article] Arf1 and Arf6 Synergistically Maintain Survival of T Cells during Activation2020
- Author(s)
  Sumiyoshi Mami、Kotani Yui、Ikuta Yuki、Suzue Kazutomo、Ozawa Madoka、Katakai Tomoya、Yamada Taketo、Abe Takaya、Bando Kana、Koyasu Shigeo、Kanaho Yasunori、Watanabe Toshio、Matsuda Satoshi
- Journal Title
  
  The Journal of Immunology
  
  Volume: 206 Issue: 2 Pages: 366-375
- DOI
  10.4049/jimmunol.2000971
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07555, KAKENHI-PROJECT-19K22528, KAKENHI-PLANNED-18H05417, KAKENHI-PROJECT-18H02601, KAKENHI-PROJECT-19H03519, KAKENHI-PROJECT-19K22542, KAKENHI-PROJECT-19K16701, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-20K06545
[Journal Article] Chlorpromazine eliminates acute myeloid leukemia cells by perturbing subcellular localization of FLT3-ITD and KIT-D816V.2020
- Author(s)
  Shinya Rai, Hirokazu Tanaka*, Mai Suzuki, J. Luis Espinoza, Takahiro Kumode, Akira Tanimura, Yasuyoshi Morita, Yoichi Tatsumi, Takafumi Yokota, Kenji Oritani, Toshio Watanabe, Yuzuru Kanakura, and Itaru Matsumura.
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 4147-4147
- DOI
  10.1038/s41467-020-17666-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06545, KAKENHI-PROJECT-20K08743, KAKENHI-PROJECT-18K08375
[Journal Article] Picalm reduction exacerbates tau pathology in a murine tauopathy model.2020
- Author(s)
  Kunie Ando, Robert De Decker, Cristina Vergara, Zehra Yilmaz, Salwa Mansor, Valerie Suain, Kristel Sleegers, Marie-Claude Potier, Charles Duyckaerts, Toshio Watanabe, Luc Buee, Karelle Leroy, Jean-Pierre Brion and the Brainbank Neuro-CEB Neuropathology Network.
- Journal Title
  
  Acta Neuropathologica
  
  Volume: 139 Issue: 4 Pages: 773-789
- DOI
  10.1007/s00401-020-02125-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06545
[Journal Article] BRCA1-interacting protein OLA1 requires interaction with BARD1 to regulate centrosome number.2018
- Author(s)
  Yoshino Y, Qi H, Fujita H, Shirota M, Abe S, Komiyama Y, Shindo K, Nakayama M, Matsuzawa A, Kobayashi A, Ogoh H, Watanabe T, Ishioka C and Chiba N.
- Journal Title
  
  Molecular Cancer Research
  
  Volume: 6(10) Issue: 10 Pages: 1499-1511
- DOI
  10.1158/1541-7786.mcr-18-0269
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H04690, KAKENHI-PROJECT-16K07296
[Journal Article] Increased centrosome number in BRCA-related breast cancer specimens determined by immunofluorescence analysis2018
- Author(s)
  Gou Watanabe, Natsuko Chiba, Tadashi Nomizu, Akihiko Furuta, Kaolu Sato, Minoru Miyashita, Hiroshi Tada, Akihiko Suzuki, Noriaki Ohuchi, Takanori Ishida
- Journal Title
  
  Cancer Science
  
  Volume: 印刷中
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H04690
[Journal Article] 1.Increased centrosome number in BRCA-related breast cancer specimens determined by immunofluorescence analysis.2018
- Author(s)
  Watanabe G, Chiba N, Nomizu T, Furuta A, Sato K, Miyashita M, Tada H, Suzuki A, Ohuchi N, Ishida T.
- Journal Title
  
  Cancer Science
  
  Volume: in press Issue: 6 Pages: 2027-2035
- DOI
  10.1111/cas.13595
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15006, KAKENHI-PROJECT-16H04690
[Journal Article] PI3K‐AKT pathway for oligodendrocyte differentiation: Targeted inactivation of PTPRZ activity in mice2018
- Author(s)
  Naomi Tanga, Kazuya Kuboyama, Ayako Kishimoto, Hiroshi Kiyonari, Aki Shiraishi, Ryoko Suzuki, Toshio Watanabe, Akihiro Fujikawa, and Masaharu Noda
- Journal Title
  
  Glia
  
  Volume: 67 Issue: 5 Pages: 967-984
- DOI
  10.1002/glia.23583
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07069, KAKENHI-PROJECT-17K07355, KAKENHI-PROJECT-16K07296
[Journal Article] PKM1 Confers Metabolic Advantages and Promotes Cell-Autonomous Tumor Cell Growth.2018
- Author(s)
  M Morita, T Sato, M Nomura, Y Sakamoto, Y Inoue, R Tanaka, S Ito, K Kurosawa, K Yamaguchi, Y Sugiura, H Takizaki, Y Yamashita, R Katakura, I Sato, Y Okada, H Watanabe, G Kondoh, et al.
- Journal Title
  
  Cancer Cell
  
  Volume: 12 Issue: 3 Pages: 355-367
- DOI
  10.1016/j.ccell.2018.02.004
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07296, KAKENHI-PROJECT-16K09597, KAKENHI-PROJECT-16K10486, KAKENHI-PROJECT-17K19620, KAKENHI-PROJECT-17K16876, KAKENHI-PLANNED-25111006, KAKENHI-PROJECT-16H04730, KAKENHI-PROJECT-15K09237, KAKENHI-PROJECT-15K21098, KAKENHI-PROJECT-16K19745, KAKENHI-PROJECT-17K07187, KAKENHI-PUBLICLY-17H05534, KAKENHI-PUBLICLY-17H06011, KAKENHI-PROJECT-16K10774, KAKENHI-PROJECT-17K19606, KAKENHI-PLANNED-17H06301, KAKENHI-PROJECT-16K07187, KAKENHI-PROJECT-17K07231
[Journal Article] Loss of protein phosphatase 6 in mouse keratinocytes enhances K-ras G12D -driven tumor promotion2018
- Author(s)
  Kurosawa Koreyuki、Inoue Yui、Kakugawa Yoichiro、Yamashita Yoji、Kanazawa Kosuke、Kishimoto Kazuhiro、Nomura Miyuki、Momoi Yuki、Sato Ikuro、Chiba Natsuko、Suzuki Mai、Ogoh Honami、Yamada Hidekazu、Miura Koh、Watanabe Toshio、Tanuma Nobuhiro、Tachi Masahiro、Shima Hiroshi
- Journal Title
  
  Cancer Science
  
  Volume: 109 Issue: 7 Pages: 2178-2187
- DOI
  10.1111/cas.13638
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07187, KAKENHI-PROJECT-17K10660, KAKENHI-PROJECT-18K16043, KAKENHI-PROJECT-16H04690, KAKENHI-PROJECT-16K07296, KAKENHI-PROJECT-16K10486, KAKENHI-PROJECT-16K10774, KAKENHI-PROJECT-17K16358, KAKENHI-PROJECT-17K16876, KAKENHI-PROJECT-18K09243, KAKENHI-PROJECT-16K07187, KAKENHI-PROJECT-17K19620
[Journal Article] Herpes Simplex Virus 1 VP22 Inhibits AIM2-Dependent Inflammasome Activation to Enable Efficient Viral Replication.2018
- Author(s)
  Maruzuru Y, Ichinohe T, Sato R, Miyake K, Okano T, Suzuki T, Koshiba T, Koyanagi N, Tsuda S, Watanabe M, Arii J, Kato A, Kawaguchi Y.
- Journal Title
  
  Cell Host Microbe.
  
  Volume: 23 Issue: 2 Pages: 254-265
- DOI
  10.1016/j.chom.2017.12.014
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08851, KAKENHI-PROJECT-16K15280, KAKENHI-PROJECT-26293102, KAKENHI-PROJECT-26713017, KAKENHI-ORGANIZER-16H06429, KAKENHI-PLANNED-16H06433, KAKENHI-PROJECT-16H06388, KAKENHI-PROJECT-15H04730, KAKENHI-PROJECT-16H05193, KAKENHI-PROJECT-15J09601, KAKENHI-PROJECT-26460548, KAKENHI-PROJECT-15K15138, KAKENHI-PROJECT-17K19549, KAKENHI-PUBLICLY-18H04863, KAKENHI-PUBLICLY-18H04968, KAKENHI-PROJECT-17H03667, KAKENHI-PROJECT-17K19561, KAKENHI-PROJECT-17H05069, KAKENHI-PROJECT-16H06276
[Journal Article] Mllt10 knockout mouse model reveals critical role of Af10-dependent H3K79 methylation in midfacial development2017
- Author(s)
  2.Honami Ogoh, Kazutsune Yamagata, Tomomi Nakao, Lisa L. Sandell, Ayaka Yamamoto, Aiko Yamashita, Naomi Tanga, Mai Suzuki, Takaya Abe, Issay Kitabayashi, Toshio Watanabe, Daisuke Sakai
- Journal Title
  
  Scientfic Reports
  
  Volume: 7 Issue: 1 Pages: 11922-11922
- DOI
  10.1038/s41598-017-11745-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07084, KAKENHI-PROJECT-16K07296, KAKENHI-PROJECT-16J02655, KAKENHI-PUBLICLY-17H05965
[Journal Article] ADP-ribosylation factor 1.2017
- Author(s)
  Toshio Watanabe and Mami Sumiyoshi.
- Journal Title
  
  Encyclopedia of Signaling Molecules, 2nd Edition
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K07296
[Journal Article] Abrogation of protein phosphatase 6 promotes skin carcinogenesis induced by DMBA2015
- Author(s)
  Hayashi K, Momoi Y , Tanuma N, Kishimoto A, Ogoh H, Kato H, Suzuki M, Sakamoto Y, Inoue Y, Nomura M, Kiyonari H, Sakayori M, Fukamachi K, Kakugawa Y, Yamashita Y, Ito S, Sato I, Suzuki A, Nishio M, Suganuma M, Watanabe T, and Shima H
- Journal Title
  
  Oncogene
  
  Volume: 印刷中 Issue: 35 Pages: 4647-55
- DOI
  10.1038/onc.2014.398
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24570159, KAKENHI-PROJECT-24591928, KAKENHI-PROJECT-25861168, KAKENHI-PROJECT-15K10081, KAKENHI-PROJECT-26430130, KAKENHI-PROJECT-15K19081, KAKENHI-PROJECT-15K20237, KAKENHI-PROJECT-25430163
[Journal Article] The ADP-ribosylation factor 1 gene is indispensable for mouse embryonic development after implantation2014
- Author(s)
  Natsuki Hayakawa**, Honami Ogoh**, Mami Sumiyoshi**, Kananko Miyamoto, Yasuhisa Matsui, Saori Nishikawa, Yuko Maede, Hiroshi Kiyonari, Mai Suzuki, and Toshio Watanabe
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 453 Pages: 748-753
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24570159
[Journal Article] Clathrin assembly protein CALM Plays a Critical Role in KIT Signaling by Regulating Its Cellular Transport from Early to Late Endosomes in Hematopoietic Cells.2014
- Author(s)
  Shinya Rai, Hirokazu Tanaka*, Mai Suzuki , Honami Ogoh, Yasuhiro Taniguchi, Yasuyoshi Morita, Takahiro Shimada, Akira Tanimura, Keiko Matsui, Takafumi Yokota, Kenji Oritani, Kenji Tanabe, Toshio Watanabe, Yuzuru Kanakura, and Itaru Matsumura
- Journal Title
  
  PLoS ONE
  
  Volume: 該当しない Issue: 10 Pages: 0109441-0109441
- DOI
  10.1371/journal.pone.0109441
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24570159, KAKENHI-PUBLICLY-25130712, KAKENHI-PROJECT-25461439, KAKENHI-PROJECT-26461412
[Journal Article] Decreased CALM expression reduces Aβ42 production ratio through clathrin-mediated endocytosis of Y-secretase.2014
- Author(s)
  金津邦彦
- Journal Title
  
  Nature Communications
  
  Volume: 5 Issue: 1 Pages: 3386-3386
- DOI
  10.1038/ncomms4386
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J10187, KAKENHI-PUBLICLY-24111511, KAKENHI-PROJECT-24570159
[Journal Article] Nuclear export signal within CALM is necessary for CALM-AF10-induced leukemia.2014
- Author(s)
  鈴木麻衣
- Journal Title
  
  Cancer Science
  
  Volume: 105 Issue: 3 Pages: 315-323
- DOI
  10.1111/cas.12347
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J10187, KAKENHI-ORGANIZER-22130001, KAKENHI-PROJECT-24570159
[Journal Article] The Arf GAP SMAP2 is necessary for organized vesicle budding from the trans-Golgi network and subsequent acrosome formation in spermiogenesis.2013
- Author(s)
  Funaki T, Kon S, Tanabe K, Natsume W, Sato S, Shimizu T, Yoshida N, Wong WF, Ogura A, Ogawa T, Inoue K, Ogonuki N, Miki H, Mochida K, Endoh K, Yomogida K, Fukumoto M, Horai R, Iwakura Y, Ito C, Toshimori K, Watanabe T, Satake M.
- Journal Title
  
  Mol. Biol. Cell
  
  Volume: 24 Issue: 17 Pages: 2633-44
- DOI
  10.1091/mbc.e13-05-0234
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23113721, KAKENHI-PROJECT-23501256, KAKENHI-PROJECT-23770148, KAKENHI-PUBLICLY-24112706, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-24570159, KAKENHI-PROJECT-24592441, KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-25293041, KAKENHI-PROJECT-25670087
[Journal Article] SMAP1 deficiency perturbs receptor trafficking and predisposes mice to myelodysplasia.2013
- Author(s)
  S Kon, N Minegishi, K Tanabe, T Watanabe, T Funaki, W F Wong, D Sakamoto, Y Higuchi, H Kiyonari, K Asano, Y Iwakura, M Fukumoto,　M Osato, M Sanada, S Ogawa, T Nakamura and M Satake
- Journal Title
  
  Journal of Clinical Investigation
  
  Volume: 123 Pages: 1123-1137
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24570159
[Journal Article] The clathrin assembly protein PICALMis required for erythroid maturationand transferrin internalization in mice2012
- Author(s)
  Suzuki M, Tanaka H, Tanimura A, Tanabe K, Oe N, Rai S, Kon S, Fukumoto M,Takei K, Abe T, Matsumura I, Kanakura Y, Watanabe T.
- Journal Title
  
  PLoS One.
  
  Volume: 7(2)
- Data Source
  KAKENHI-PROJECT-22590298
[Journal Article] The clathrin assembly protein PICALM is required for erythroid maturation and transferrin internalization in mice.2012
- Author(s)
  鈴木麻衣
- Journal Title
  
  PLoS ONE
  
  Volume: 7 Issue: 2 Pages: 31854-31854
- DOI
  10.1371/journal.pone.0031854
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J10187, KAKENHI-PUBLICLY-23113721, KAKENHI-PROJECT-23370089, KAKENHI-PROJECT-23659213, KAKENHI-PROJECT-23770148, KAKENHI-PROJECT-24570159, KAKENHI-PROJECT-24659174, KAKENHI-PUBLICLY-23130513
[Journal Article] IDH1/2 gene status defines the prognosis and molecular profiles in patients with grade III gliomas.2012
- Author(s)
  Shibahara I, Sonoda Y, Kanamori M, Saito R, Yamashita Y, Kumabe T, Watanabe M, Suzuki H, Kato S, Ishioka C, Tominaga T.
- Journal Title
  
  Int J Clin Oncol
  
  Volume: 17(6) Pages: 551-61
- NAID
  10031155913
- Data Source
  KAKENHI-PROJECT-22590298
[Journal Article] Transgene insertion in intronic sequences of Mdga2 gene shows methylation in an imprinted manner in an Acrodysplasia (Adp) mouse line.2012
- Author(s)
  Mai Suzuki, Davor Solter, and Toshio Watanabe.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 418 Pages: 439-444
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24570159
[Journal Article] Biological Implications filamin A-bound PEBP2β/CBFβ retention in the cytoplasm.2005
- Author(s)
  Watanabe, T.et al.
- Journal Title
  
  (Review)
- Data Source
  KAKENHI-PROJECT-15659064
[Journal Article] Biological implications filamin A-bound PEBP2β/CBFβ retention in the cytoplasm.2005
- Author(s)
  Watanabe, T. et al.
- Journal Title
  
  (Review)
- Data Source
  KAKENHI-PROJECT-15039201
[Presentation] Arfによるミトコンドリアの機能制御とT細胞の生存維持2022
- Author(s)
  住吉麻実、松尾禎之、小谷唯、笹田萌未、渡邊利雄、松田達志
- Organizer
  KTCC
- Data Source
  KAKENHI-PROJECT-20K06545
[Presentation] 神経系における脱リン酸化酵素PP6の機能解析2022
- Author(s)
  松岡未樹, 酒井大輔, 島礼, 渡邊利雄
- Organizer
  【2021年度先端モデル動物支援P】成果発表会
- Data Source
  KAKENHI-PROJECT-20K06545
[Presentation] Functional analysis of protein phosphatase PP6 in the nervous system.2022
- Author(s)
  Miki Matsuoka，Daisuke Sakai，Hiroshi Shima，Toshio Watanabe.
- Organizer
  The Protein Phosphatases Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06545
[Presentation] 恒常活性化型Rasを導入したMEF細胞における脱リン酸化酵素PP6の欠損効果の解析発がん性K-Rasが自然免疫応答に及ぼす影響2022
- Author(s)
  柴田万絢 , 村井与心 , 田沼延公 , 島礼 , 渡邊利雄
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K06545
[Presentation] Mul1欠損メスマウスが示す不妊の原因解析2022
- Author(s)
  中井杏, 吉岡ゆきの, 安田恵子, 小柴琢己, 渡邊利雄
- Organizer
  【2021年度先端モデル動物支援P】成果発表会
- Data Source
  KAKENHI-PROJECT-20K06545
[Presentation] ミトコンドリア局在ユビキチンリガーゼが初期胚発生に与える影響2022
- Author(s)
  福嶋優希, 中井杏, 小柴琢己, 渡邊利雄
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K06545
[Presentation] Arf1-BKOマウスではGerminal center B細胞が消失する2022
- Author(s)
  小谷唯、住吉麻実、笹田萌未、小澤まどか、片貝智哉、渡邊利雄、松田達志
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K06545
[Presentation] 恒常活性化型Rasを導入したMEF細胞における脱リン酸化酵素PP6の欠損効果の解析2022
- Author(s)
  伊藤舞 , 島礼 , 田沼延公 , 渡邊利雄
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K06545
[Presentation] RNAウイルス感染応答における脱リン酸化酵素PP6の機能解析2022
- Author(s)
  村井与心 , 田沼延公 , 島礼 , 渡邊利雄
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K06545
[Presentation] Mul1欠損メスマウスが示す不妊の解析2022
- Author(s)
  中井杏 , 小柴琢己 , 渡邉利雄
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K06545
[Presentation] Mul1欠損メスマウスが示す不妊の解析2021
- Author(s)
  中井　杏、吉岡　ゆきの、小柴　琢己、渡邊利雄
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K06545
[Presentation] 神経系における脱リン酸化酵素PP6の機能解析2021
- Author(s)
  松岡　未樹、酒井　大輔、島　礼、渡邊利雄
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K06545
[Presentation] Mul1遺伝子欠損メスマウスにおける不妊の原因解析2021
- Author(s)
  吉岡　ゆきの、中井　杏、小柴　琢己、渡邊利雄
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K06545
[Presentation] 肥満細胞における低分子量Gタンパク質Arf1の機能解明2021
- Author(s)
  小谷唯、住吉麻実、笹田萌未、渡邊利雄、松田達志
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K06545
[Presentation] p53標的遺伝子p53PAD5は腸管上皮細胞にストレス抵抗性を付与する。2021
- Author(s)
  山本樹、青木清乃、山本　采佳、山野　荘太郎、大島　正伸、八尾　良司、渡邊　利雄、田中知明、大木理恵子
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K06545
[Presentation] 低分子量Gタンパク質Arf1による膜ブレブの制御2021
- Author(s)
  堤弘次, 長谷川稜, 戸田あかり, 堀羽衣音, 渡邊利雄, 太田安隆
- Organizer
  第７３回日本細胞生物学会年会
- Data Source
  KAKENHI-PROJECT-20K06545
[Presentation] 神経系における脱リン酸化酵素PP6の機能解析2021
- Author(s)
  松岡未樹、渡邊利雄
- Organizer
  第67 回日本生化学会近畿支部例会
- Data Source
  KAKENHI-PROJECT-20K06545
[Presentation] ウイルス感染に対するMul1欠損細胞の応答解析　Analysis of how Mul1-KO MEFs response to virus infection.2020
- Author(s)
  天津友貴、松尾尚輝、山本采佳、中嵜詩乃、小河穂波、一戸猛志、小柴琢己、渡邊利雄
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K06545
[Presentation] Mul1遺伝子欠損マウスは不妊性を示す　Mul1-deficient mice show infertility.2020
- Author(s)
  吉岡ゆきの、天津友貴、山本采佳、安田恵子、小柴琢己、渡邊利雄
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K06545
[Presentation] ウイルス感染に対するMul1欠損マウスの応答解析2019
- Author(s)
  天津友貴、松尾尚輝、山本采佳、中嵜詩乃、小河穂波、一戸猛志、小柴琢己、渡邊利雄
- Organizer
  H30年度文部科学省新学術領域研究・学術研究支援基盤形成「先端モデル動物支援プラットフォーム」成果発表会
- Data Source
  KAKENHI-PROJECT-16K07296
[Presentation] ウイルス感染に対するMul1欠損マウスの応答解析2018
- Author(s)
  天津友貴、松尾尚輝、山本采佳、中嵜詩乃、小河穂波、一戸猛志、小柴琢己、渡邊利雄
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K07296
[Presentation] Arf1とArf6の両方を欠損するMEF細胞株取得の試み2018
- Author(s)
  中嵜詩乃、増田成美、早川夏姫、住吉麻実、金保安則、松田達志、渡邊利雄
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K07296
[Presentation] Tie2-Creにより誘導した組織特異的なPpp6cの欠損はマウスの胚発生における異常を引き起こす2018
- Author(s)
  加藤里佳、小河穂波、岸本綾子、鈴木麻衣、田沼延広、島礼、渡邊利雄
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K07296
[Presentation] issue Specific Deletion of Protein Phosphatase 6 Catalytic Subunit (Ppp6c) Caused Embryonic lethality and postnatal death.2018
- Author(s)
  Watanabe Toshio, Kato Rika, Ogoh Honami, Kishimoto Ayako, Suzuki Mai, Tanuma Nobuhiro, and Shima Hiroshi
- Organizer
  Workshop on Frontiers in Phosphatase Research and Drug Discovery.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07296
[Presentation] Tie2-Cre Induced Tissue Specific Deletion of Ppp6c Caused Abnormal Hematopoiesis during Mouse Embryogenesis.2018
- Author(s)
  Kato Rika, Ogoh Honami, Kishimoto Ayako, Suzuki Mai, Tanuma Nobuhiro, Shima Hiroshi and Watanabe Toshio
- Organizer
  Workshop on Frontiers in Phosphatase Research and Drug Discovery.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07296
[Presentation] Tumor suppressor activity of protein phosphatase 62018
- Author(s)
  Koreyuki Kurosawa, Yoichiro Kakugawa, Nobuhiro Tanuma, Toshio Watanabe, and Hiroshi Shima
- Organizer
  Workshop on Frontiers in Phosphatase Research and Drug Discovery.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07296
[Presentation] T細胞特異的Arf欠損マウスの解析2018
- Author(s)
  住吉麻実、渡邊利雄、松田達志
- Organizer
  第28回Kyoto T cell Conference
- Data Source
  KAKENHI-PROJECT-16K07296
[Presentation] AF10 links histone chaperones Supt6h and FACT complex to MLL-fusion leukemia.2018
- Author(s)
  Kazutsune Yamagata, Mariko Saito, Mai Suzuki, Honami Ogo, Toshio Watanabe and Issay Kitabayashi.
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K07296
[Presentation] 脱リン酸化酵素PP6は、がん抑制遺伝子として働く2018
- Author(s)
  島礼、渡邊利雄、田沼延公
- Organizer
  第91回日本生化学会大会シンポジウム、「リン酸化ー脱リン酸化応答とがん」
- Invited
- Data Source
  KAKENHI-PROJECT-16K07296
[Presentation] B細胞における低分子量Gタンパク質Arf経路の機能解明2018
- Author(s)
  小谷唯、住吉麻実、江口稚佳子、金保安則、渡邊利雄、松田達志
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K07296
[Presentation] ウイルス感染に対するMul1欠損マウスの応答解析2018
- Author(s)
  天津友貴、山本采佳、中嵜詩乃、小河穂波、一戸猛志、渡邊利雄、小柴琢己
- Organizer
  先端モデル動物支援　若手技術講習会
- Data Source
  KAKENHI-PROJECT-16K07296
[Presentation] マウスSmap1, Smap2二重欠損胚は原腸形成期において異常を示す2018
- Author(s)
  大桑良菜、大塚瑞希、住吉麻実、小河穂波、木村-吉田千春、松尾勲、渡邊利雄
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K07296
[Presentation] Af10 regulates mid facial development via H3K79 methylation2018
- Author(s)
  Honami Ogoh, Kazutsune Yamagata, Tomomi Nakao, Lisa L. Sandell, Issay Kitabayashi, Toshio Watanabe and Daisuke Sakai
- Organizer
  Gordon Research Seminar &Conference "Craniofacial Morphogenesis & Tissue Regeneration" Understanding Mechanisms of Craniofacial Development, Disease and Regeneration.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07296
[Presentation] オートファジーによるtype 2A protein phosphataseの制御機構の解明2017
- Author(s)
  原信行、渋谷周作、坂井祐介、島礼、渡邊利雄、大島浩子、大島正伸、齋藤達哉、審良静男、永野浩昭、臼井達哉、大浜剛、佐藤晃一
- Organizer
  2017年度生命科学系学会合同年次大会/第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K07296
[Presentation] 小胞輸送を制御するArf GTPase 活性化因子SMAP1とSMAP2の二重欠損胚におけるエンドサイトーシス経路の異常2017
- Author(s)
  大塚瑞希、大桑良菜、住吉麻実、増田成美、小河穂波、木村-吉田千春、松尾勲、渡邊利雄
- Organizer
  2017年度生命科学系学会合同年次大会/第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K07296
[Presentation] 低分子量Gタンパク質Arf1の全身性欠損は胎生致死となり、神経幹細胞特異的欠損は誕生後の脳の矮小化と後肢の運動の異常とを呈する2017
- Author(s)
  薗部なな子、増田成美、早川夏姫、住吉麻実、生田優希、丹賀直美、小河穂波、鈴木麻衣、二口充、新谷隆史、田沼延広、島礼、渡邊利雄
- Organizer
  平成28年度「先端モデル動物支援プラットフォーム成果発表会」
- Place of Presentation
  大津
- Year and Date
  2017-02-09
- Data Source
  KAKENHI-PROJECT-16K07296
[Presentation] BRCA1の新規結合分子Ola1のノックアウトマウスの表現型の解析.2017
- Author(s)
  吉田貴大, 吉野優樹, 小河穂波, 佐々木伯大, 中村保宏, 渡邊利雄, 千葉奈津子.
- Organizer
  生命科学系学会合同年次大会　ConBio2017
- Data Source
  KAKENHI-PROJECT-16H04690
[Presentation] 細胞膜近傍でのクラスリン集合を担うCALMの欠損は何故MVB/後期エンドソームを介する分解経路の異常を引き起こす原因を探る2017
- Author(s)
  増田成美、住吉麻実、小河穂波、鈴木麻衣、渡邊利雄
- Organizer
  2017年度生命科学系学会合同年次大会/第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K07296
[Presentation] Ppp6cは、マウス皮膚のがん抑制遺伝子として働く2017
- Author(s)
  黒沢　是之、野村美有、角川陽一郎、山下洋二、三浦康、山田秀和、松浦一登、佐藤郁郎、田沼延公、渡邊利雄、島礼
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K07296
[Presentation] ヒストンシャペロンSupt6hとFACT複合体は、AF10との結合を介してMLL転座関連白血病の発症に寄与する2017
- Author(s)
  山形和恒、斎藤真理子、鈴木麻衣、小河穂波、渡邊利雄、北林一生
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K07296
[Presentation] T細胞における低分子量Gタンパク質Arfファミリーの機能解析2017
- Author(s)
  住吉麻実、江口稚佳子、小河穂波、小谷唯、伊藤量基、神田晃、金保安則、渡邊利雄、松田達志
- Organizer
  2017年度生命科学系学会合同年次大会/第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K07296
[Presentation] 制御性T細胞の分化誘導に関わるシグナル伝達経路の解明2017
- Author(s)
  小谷唯、住吉麻実、伊藤量基、神田晃、平尾敦、渡邊利雄、松田達志
- Organizer
  2017年度生命科学系学会合同年次大会/第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K07296
[Presentation] BRCA1の新規結合分子Ola1のノックアウトマウスの表現型の解析2017
- Author(s)
  吉田貴大、吉野優樹、小河穂波、佐々木伯大、渡邊利雄、千葉奈津子
- Organizer
  2017年度生命科学系学会合同年次大会/第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K07296
[Presentation] マスト細胞脱顆粒過程におけるPI3K経路の役割解明2016
- Author(s)
  松田達志、江口稚佳子、住吉麻実、生田優希、小河穂波、丹賀直美、早川夏姫、渡邊利雄
- Organizer
  第３９回日本分子生物学会年会
- Place of Presentation
  横浜（パシフィコ横浜）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K15157
[Presentation] 神経幹細胞特異的にArf1を欠損させたマウスに見られた、誕生後の異常の解析。2016
- Author(s)
  薗部なな子、早川夏姫、増田成美、小河穂波、早川夏姫、住吉麻実、生田優希、丹賀直美、鈴木麻衣、二口充、新谷隆史、渡邊利雄
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K07296
[Presentation] 小胞輸送を制御するArf GTPase 活性化因子Smap1とSmap2の二重欠損によるマウス胚の表現型の解析2016
- Author(s)
  大塚瑞希、住吉麻実、増田成美、小河穂波、木村-吉田千春、松尾勲、渡邊利雄
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-16K07296
[Presentation] 中心体制御因子Ola1ノックアウトマウスに自然発生した造血器系腫瘍の病理組織学的解析2016
- Author(s)
  飯地雄大、吉野優樹、中村保宏、小河穂波、二口充、藤田拡樹、渡邉利雄、千葉　奈津子
- Organizer
  第20回造血器腫瘍研究会
- Place of Presentation
  かずさアカデミアホール（千葉県・木更津市）
- Year and Date
  2016-01-23
- Data Source
  KAKENHI-PROJECT-24300327
[Presentation] 遺伝子改変マウスを用いたArf1の胚発生での機能と神経系での機能の解析の試み。2016
- Author(s)
  渡邊利雄、薗部なな子、生田優希、小河穂波、宮本可南子、丹賀直美、鈴木麻衣、西川紗織、新谷隆史、島礼
- Organizer
  第89回日本生化学会大会　シンポジウム
- Place of Presentation
  仙台
- Year and Date
  2016-09-26
- Invited
- Data Source
  KAKENHI-PROJECT-16K07296
[Presentation] FcεRIα-Creノックインマウスを用いたマスト細胞機能の解析2015
- Author(s)
  松田達志、江口稚佳子、金光沙也加、渡邊利雄
- Organizer
  第３８回日本分子生物学会年会・第８８回日本生化学会大会合同大会
- Place of Presentation
  神戸国際会議場（兵庫県・神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K15157
[Presentation] クラスリン集合タンパク質CALM欠損が及ぼすメラニン産生への影響。2015
- Author(s)
  大野絹代, 増田成美, 小河穂波,住吉麻実,早川夏姫, 稲垣綾華, 大塚瑞希, 中尾知美, 鈴木麻衣, 田中宏和, 森田詠子, 酒井良明, 渡邊利雄
- Organizer
  第62回日本生化学会近畿支部例会
- Place of Presentation
  草津、滋賀県
- Year and Date
  2015-05-16
- Data Source
  KAKENHI-PROJECT-24570159
[Presentation] The involvement of mTORC1 in croton oil-induced cytokine expression by mouse keratinocytes.2015
- Author(s)
  Akio Manabe, Naoko Watanabe, Masashi Ohtani
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸ポートピアホテル（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25460602
[Presentation] 融合遺伝子による白血病幹細胞の制御機構。2014
- Author(s)
  鈴木麻衣、山形和恒、齋藤眞理子、渡邊利雄、北林一生
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-27
- Invited
- Data Source
  KAKENHI-PROJECT-24570159
[Presentation] ジホモ-γ-リノレン酸産生酵母菌の経口投与による皮膚炎症応答の抑制効果2014
- Author(s)
  寺津聡一郎、大谷真志、矢澤彌、植村浩、渡辺直子
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2014-11-27
- Data Source
  KAKENHI-PROJECT-25460602
[Presentation] CALM-AF10の白血病誘導にはCALMが有する核外移行シグナルの機能が必須である。2014
- Author(s)
  鈴木麻衣, 篠実花, 相川祐規子, 渡邊利雄, 北林一生
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-18
- Invited
- Data Source
  KAKENHI-PROJECT-24570159
[Presentation] SMAP（Small Arf GAP）1,2両遺伝子欠損胚は致死でアポトーシスを起こしている。2014
- Author(s)
  住吉麻実、小河穂波、早川夏姫、鈴木麻衣、松居靖久、渡邊利雄
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-PROJECT-24570159
[Presentation] 遺伝学的アルツハイマー病予防因子PICALM/CALMが病態形成に寄与する分子機構の解明。2014
- Author(s)
  金津邦彦, 渡邊利雄, 岩坪威, 富田泰輔
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-18
- Invited
- Data Source
  KAKENHI-PROJECT-24570159
[Presentation] CALM-AF10融合遺伝子のCALMによる白血病発症と赤血球造血への役割2013
- Author(s)
  鈴木麻衣、田中宏和、松村到、金倉譲、北林一生、渡邊利雄
- Organizer
  個体レベルのがん研究ワークショップ
- Place of Presentation
  大津
- Invited
- Data Source
  KAKENHI-PROJECT-24570159
[Presentation] Embryonic Lethality Caused in Mice LPP6c gene2013
- Author(s)
  Ogoh H, Kishimoto A, Suzuki M, Hara K, Tanga N, Tanuma N, Watanabe T andShima H
- Organizer
  10th International Conference on Protein Phosphatase
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-22590298
[Presentation] mTOR complex 1 regulates B cell development.2013
- Author(s)
  Ohtani, M., Fujii, H., Sakai, K., Hoshii, T., Watanabe, T., Koyasu, S., Hirao, A., and Matsuda, S.
- Organizer
  マクロファージ分子細胞生物学国際シンポジウム合同学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25460602
[Presentation] mTOR complex 1 regulates B cell development through IgHm expression.2013
- Author(s)
  Ohtani, M., Watanabe, T., Hoshii, T., Koyasu, S., Ohara, O., Hirao, A., Kubo, M., and Matsuda, S.
- Organizer
  日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25460602
[Presentation] CALM-AF10のCALM部分はどのように白血病発症へ関与するか2013
- Author(s)
  鈴木麻衣、篠実花、相川祐規子、田中宏和、松村到、金倉譲、北林一生、渡邊利雄
- Organizer
  第17回　造血器腫瘍研究会
- Place of Presentation
  宮崎
- Data Source
  KAKENHI-PROJECT-24570159
[Presentation] CALM LINKS CYTOKINE SIGNALS TO HEMATOPOIETIC CELL GROWTH AND SURVIVAL BY REGULATING INTRACELLULAR TRAFFICKING OF RECEPTOR TYROSINE KINASES.2013
- Author(s)
  Shinya Rai, Hirokazu Tanaka, Mai Suzuki, Akira Tanimura, Keiko Matsui, Toshio Watanabe, Yuzuru Kanakura, Itaru Matsumura.
- Organizer
  18th Congress of the European Hematology Association
- Place of Presentation
  Stockholm, Sweden
- Data Source
  KAKENHI-PROJECT-24570159
[Presentation] PP6触媒サブユニット遺伝子は、胚の初期発生時期に必須である2012
- Author(s)
  渡邊利雄、田沼延公、島礼
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22590298
[Presentation] ピルビン酸キナーゼM(PKM)の発現アイソフォーム固定したマウスの作出2012
- Author(s)
  田沼延公、岸本綾子、松本祥子、野村美有樹、近藤玄、国下侑里、片倉隆一、佐藤雅美、渡邊利雄、島礼
- Organizer
  第85回日本生化学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22590298
[Presentation] SMAP（Small Arf GAP）1,2両遺伝子欠損胚は致死である。2012
- Author(s)
  原華苗、今井恵理、鈴木麻衣、昆俊介、田邊賢司、船木智、佐竹正延、松居靖久、渡邊利雄
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  博多
- Data Source
  KAKENHI-PROJECT-24570159
[Presentation] ワールブルグ効果に関するin vivo解析のためのマウスモデル開発2012
- Author(s)
  松本祥子、岸本綾子、国下侑里、近藤玄、野村美有樹、渡邊利雄、島礼、田沼延公
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22590298
[Presentation] クラスリン集合因子CALMの欠損はトランスフェリンを介した鉄の取り込みを減少させ造血障害を起こす2012
- Author(s)
  鈴木麻衣、田中宏和、谷村朗、田邊賢司、大江夏子、頼晋也、昆俊亮、福本学、竹居孝二、松村到、金倉譲、渡邊利雄
- Organizer
  【第35回日本分子生物学会年会】ワークショップ
- Place of Presentation
  博多
- Invited
- Data Source
  KAKENHI-PROJECT-24570159
[Presentation] ES細胞におけるピルビン酸キナーゼM(PKM)アイソフォームの機能解析‐ノックイン細胞を用いて2012
- Author(s)
  田沼延公、岸本綾子、国下侑里、松本祥子、近藤玄、坂本良美、野村美有樹、渡邊利雄、島礼
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22590298
[Presentation] PKMスイッチ不可能なマウスモデル2012
- Author(s)
  田沼延公、渡邊利雄、野村美有樹、佐藤郁郎、椎葉健一、山下洋二、佐藤雅美、島礼
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22590298
[Presentation] Embryonic Lethality Caused in Mice Lacking the phosphatase domain of thePP6c gene2011
- Author(s)
  Kishimoto A, Tanuma N, Suzuki M, Sasaki, N Abe T, Kiyonari H, Aizawa S-i,Watanabe T, Shima H
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22590298
[Presentation] Arf GTPase活性化因子のSMAP1,2の個体機能解析の試み2009
- Author(s)
  渡邊利雄
- Organizer
  日本プロテインホスファターゼ研究会学術集会
- Place of Presentation
  熊本大学・遺伝子実験施設
- Year and Date
  2009-11-14
- Data Source
  KAKENHI-PROJECT-20057016
[Presentation] 小胞形成開始因子のArf1 conditional ノックアウトマウスの作製。
- Author(s)
  生田優希、早川夏姫、小河穂波、鈴木麻衣、阿部高也、清成寛、相沢慎一、渡邊利雄
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24570159
[Presentation] SMAP（Small Arf GAP）1, 2両遺伝子欠損MEF細胞株の樹立
- Author(s)
  住吉麻実、原華苗、小河穂波、鈴木麻衣、昆俊介、田邊賢司、佐竹正延、田沼延公、島礼、渡邊利雄
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24570159
[Presentation] 小胞形成開始因子Arf1を欠損した胚盤胞のin vitro培養下での増殖解析。
- Author(s)
  早川夏姫、生田優希、小河穂波、住吉麻実、原華苗、鈴木麻衣、渡邊利雄
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24570159
[Presentation] 家族性乳がん原因分子Brca1の新規結合分子Ola1の欠損マウスにおける発がん
- Author(s)
  千葉奈津子, 小河穂波, 藤田拡樹, 呉曦, 二口充, 渡邊利雄
- Organizer
  第19回造血器腫瘍研究会
- Place of Presentation
  佐賀
- Year and Date
  2015-01-23 – 2015-01-24
- Data Source
  KAKENHI-PROJECT-24300327
[Presentation] GTP脱リン酸化酵素のARFとその活性化因子SMAPの欠損マウス解析。
- Author(s)
  住吉麻美、早川夏姫、小河穂波、西川紗織、鈴木麻衣、昆俊介、佐竹正延、田邊賢司、田沼延公、島礼、渡邊利雄
- Organizer
  第6回日本プロテインホスファターゼ研究会学術集会
- Place of Presentation
  津
- Data Source
  KAKENHI-PROJECT-24570159
[Presentation] Nuclear export signal (NES) within CALM is necessary for CALM-AF10-mediated leukemic transformation.
- Author(s)
  鈴木麻衣、篠実花、相川祐規子、渡邊利雄、北林一生
- Organizer
  第72回日本癌学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24570159
[Presentation] SMAP2はリサイクリングエンドソームからゴルジ体への物質輸送を制御する。
- Author(s)
  松平竜之、田邊賢司、渡邊利雄、田口友彦、新井洋由
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24570159
[]

1. OISHI Michio (00126004)

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2. Chiba Natsuko (50361192)

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3. NOMURA Shintaro (80159087)

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4. AYUSAWA Dai (00142109)

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5. SATAKE Masanobu (50178688)

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6. Koshiba Takumi (70403970)

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7. 穂積本男 (50113478)

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8. 白川茂 (20026850)

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10. 斎藤政樹 (60012762)

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11. 帯刀益夫 (10099971)

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12. 西森克彦 (10164609)

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13. KITABAYASHI Issay (20261175)

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14. YAMAGATA Kazutsune (70311412)

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15. ROKUDAI Susumu (50469970)

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16. YOSHIDA Hitoshi (10506710)

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17. SHIMA Hiroshi (10196462)

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18. YAMASITA Youzi (30420045)

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19. SUGAMURA Kazuo (20117360)

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20. KANNO Shin-ichiro (10400417)

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21. Sugimoto Asako (80281715)

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22. TAKEDA Masao (40030853)

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23. YAKURA Hidetaka (60166486)

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24. KASUGA Masato (50161047)

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25. MIYAMOTO Eishichi (50109659)

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26. TAMURA Shinri (20124604)

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27. KIKUCHI Kunimi (20006117)

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28. NIKI Masaru (60241626)

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29. OHTANI Masashi (20383713)

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30. NAGAI Shigenori (50348801)

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31. MATSUDA Satoshi (00286444)

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32. 日野田裕治 (10165128)

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33. 久野高義 (50144564)

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35. 吉野優樹 (60755700)

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36. SUMIYOSHI Mami

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37. JAYNES Jim

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38. JIM Jaynes

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39. KAWAI Masaaki

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40. MIYASHITA Minoru

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41. FUJIKAWA Akihiro

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42. 田邊賢司

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46. 佐藤郁郎

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WATANABE Toshio 渡邊 利雄

渡辺 利雄 ワタナベ トシオ

渡邉 利雄 ワタナベ トシオ

渡邊 利雄 ワタナベ トシオ

Research Projects

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Elucidation of physiological functions of serine threonine phosphatase PP6Principal Investigator

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Examination of involvement of vesicle transport mechanism in neurodegenerative disease using tissue specific gene deletion methodPrincipal Investigator

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Figure of true clathrin-dependent intracellular vesicle transportPrincipal Investigator

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小胞形成制御因子SMAP1,2は細胞外環境の生理機能にどう影響するかPrincipal Investigator

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新規ARF GAPによるARF Gサイクル制御と生理機能の解明Principal Investigator

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転写因子AML1によるT細胞のTh1/Th2系列への振り分け制御機構の解明Principal Investigator

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WATANABE Toshio 渡邊利雄

渡辺利雄ワタナベトシオ

渡邉利雄ワタナベトシオ

渡邊利雄ワタナベトシオ