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HANAOKA Fumio  花岡 文雄

ORCIDConnect your ORCID iD *help
… Alternative Names

花岡 文雄  ハナオカ フミオ

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Researcher Number 50012670
Other IDs
External Links
Affiliation (Current) 2025: 学習院大学, 理学部, 研究員
Affiliation (based on the past Project Information) *help 2015 – 2019: 学習院大学, 理学部, 研究員
2007 – 2015: 学習院大学, 理学部, 教授
2003 – 2007: OSAKA UNIVERSITY, GRAD. SCH. FRONT. BIOSCI., PROFESSOR, 大学院・生命機能研究科, 教授
2004 – 2006: Osaka Univ., Grad. Sch. Front. Biosci., Professor, 大学院生命機能研究科, 教授
2002 – 2003: 大阪大学, 生命機能研究科, 教授 … More
2002: 教授
2002: Osaka University, Graduate School of Frontier Biosciences, Professor, 大学院・生命機能研究所, 教授
1994 – 2001: 大阪大学, 細胞生体工学センター, 教授
1998: Osaka University, Institute for Molecular and Cellular Biology, Professor, 細菌生体工学センター, 教授
1994: 大阪大学, 細胞主体工学センター, 教授
1992 – 1994: 理化学研究所, 細胞生理, 主任研究員
1991 – 1993: RIKEN, Cell. Physiol. Lab., Chief Scientist, 細胞生理学研究室, 主任研究員
1990 – 1993: 理化学研究所, 主任研究員
1989 – 1990: 理化学研究所, 放射線生物学研究室, 主任研究員
1989: 理化学研究所, 放射線生物学部, 主任研究員
1989: 理化学研究所, 放射線生物部, 主任研究員
1987 – 1988: 東京大学, 薬学部・生理化学, 助教授
1986 – 1988: 東京大学, 薬学部, 助教授 Less
Review Section/Research Field
Principal Investigator
Biological pharmacy / Biological pharmacy / Molecular biology / Biological Sciences / Biological Sciences / Cell biology / 物質生物化学 / 代謝生物化学
Except Principal Investigator
Biological Sciences / Risk sciences of radiation and chemicals … More / Human genetics / Molecular biology / Biological pharmacy / 分子遺伝学・分子生理学 Less
Keywords
Principal Investigator
DNA修復 / 細胞周期 / 色素性乾皮症 / DNAポリメラーゼ / 紫外線 / ユビキチン / 損傷乗り越え複製 / 突然変異 / DNA複製 / DNA repair … More / REV1 / DNAポリメラーゼ・イータ / ゲノム / 発がん / 転写 / 修復 / 複製 / RB蛋白質 / 温度感受性変異株 / DNA損傷 / XPC protein / ヌクレオチド除去修復 / NER / xeroderma pigmentosum / 損傷乗り越え合成 / 癌 / ノックアウトマウス / 遺伝子 / 阻害剤 / 無細胞系 / DNAポリメラーゼalpha / サイクリン / centrin 2 / UV-DDB / nucleotide excision repair / XPCタンパク質 / translesion synthesis / 紫外線感受性 / 遺伝子ノックアウト / CPD / DNA損傷トレランス / 損傷トレランス / 色素性乾皮症バリアント / がん / コケイン症候群 / 遺伝病 / 相同的組換え / 組換え修復 / 除去修復 / スクリーニング / サポニン / 抗がん剤 / 減数分裂 / RNAポリメラーゼ / DNAポリメラーゼα / EIA遺伝子 / TGFβ / 癌抑制遺伝子 / 癌遺伝子 / cdc2キナ-ゼ / cdc2キナーゼ / マウス胚性線維芽細胞 / スクリーニング系 / 遺伝毒性 / 損傷応答 / condensin / ubiquitylation / chromatin structure / DDB因子 / CBP / ヒストンアセチル化 / コンデンシン / ユビキチン化 / クロマチン構造 / DNA polymerase τ / DNA polymerase η / thymine DNA glycosylase / HR23B protein / SUMO-I / APエンドヌクレアーゼ / 色素乾皮症 / DDB / SUMO-1 / Polι / Polη / チミンDNAグリコシラーゼ / HR23Bタンパク質 / carcinogenesis / knockout mice / DNA lesions / DNA polymerase / XP variant / XPVポリメラーゼ / 活性酸素 / polイータ / SV40T antigen / DNA helicase / saponin / anti-cancer drugs / inhibitors / cell-free system / DNA replication / SV40 T抗原 / DNAヘリカーゼ / S5a protein / 26S proteasome / HHR23B protein / Vpr protein / p53蛋白質 / XPG蛋白質 / TFIIH / ヌクレチオド除去修復 / XPE蛋白質 / RNAポリメラーゼII / S5a蛋白質 / 26Sプロテアソーム / HHR23B蛋白質 / Vpr蛋白質 / XPC蛋白質 / Genetic disease / Carcinogenesis / Mutagenesis / Homologous recombination / Recombination repair / Nucleotide excision repair / 相同的組換之 / 組換之修復 / overexpression / gene expression / primase / growth-revertants / ts mutant / DNA polumerase alpha / 遺伝子発現 / PCR-SSCP法 / 温度感受性突然変異株 / 過剰発現 / 発現制御 / プライマーゼ / 増殖復帰株 / cell-free repair system / UV light / DNA topoisomerase / nucleosome / cell-free replication system / minichromosome / SV40 virus / ス-パ-ヘリックス / SV40DNA / 無細胞修復系 / DNAトポイソメラ-ゼ / ヌクレオソ-ム / 無細胞複製系 / ミニ染色体 / SV40ウイルス / DNA複製起点 / DnaA蛋白質 / N-myc蛋白質 / ホルボールエステル / コフィリン / イノシトール輸送 / ts変異株 / 百日咳毒素 / DNA複製開始 / 情報伝達 / 増殖制御機構 / 突然変異株 / (6-4)光産物 / DNAポリメラーゼκ / TLSポリメラーゼ / ニワトリDT40 / DNAポリメラーゼ・ゼータ / X線結晶構造 / モノユビキチン化PCNA / Hsp90 / 翻訳後修飾 / シスプラチン / 紫外線損傷 / ピリミジン二量体 / WAモチーフ / 体細胞超突然変異 / シャトルベクター / モデルマウス / XPV / スフィンゴシン / DNAポリメラーゼη / X線結晶構造解析 / PCNA / DNA修復 / ゲノム再編 / 国際発信 / 領域運営 / クロマチンリモデリング / ヒストン修飾 / クロマチン / 放射線 / 複製フォーク停止 / DNAポリメラーゼ・イオタ / 分裂酵母 / タンパク質構造 / ミスマッチ修復 / ゲノム安定性 / 分離核系 / 複製-修復共役反応 / 転写-修復共役反応 / 組換え / 遺伝情報維持 / DNAトランスアクション / フォスファターゼ / TGFbeta / がん抑制遺伝子 / がん遺伝子 / cAMP / SGVIキナーゼ / RCCI遺伝子 / C^-mos産物 / C^-myc遺伝子 / PKC / CCG1遺伝子 / c-myc遺伝子 / リボゾーム修飾因子 / MAPキナーゼ / Mos蛋白質 / c-Myc蛋白質 / cdc2遺伝子 / 不死化遺伝子 / ^<cdc2>キナーゼ / RV蛋白質 / 有性生殖 / CDC28キナ-ゼ / c‐myc産物 / c‐mos遺伝子 / RNAポリメラ-ゼ / ヒストンデアセチラ-ゼ / cーmosキナ-ゼ / TGFーβ / ホスファチジルセリン / トリコスタチン / DNA複製開始点 / cーmos蛋白質 / デストリン … More
Except Principal Investigator
DNA修復 / 転写 / 色素性乾皮症 / 細胞周期 / TFIIE / DNA repair / ノックアウトマウス / TFIIH / xeroderma pigmentosum / 紫外線 / コケイン症候群 / リン酸化 / Cockayne syndrome / knockout mice / gene targeting / 遺伝子ターゲティング / GTP結合蛋白質 / DNA複製 / RNAポリメラーゼII(PolII) / 基本転写因子 / 染色体 / RBタンパク / DNAポリメラーゼ / DNA合成酵素の遺伝子 / DNA損傷 / 突然変異 / 細胞増殖 / 百日咳毒素 / トポイソメラーゼ / 癌 / ウイルス / 遺伝学 / CTD / PolII / 皮膚癌 / ミスマッチ修復 / 遺伝子クローニング / 発がん / DNA除去修復 / 情報認識機構 / 染色体凝縮 / 遺伝子ターゲッティング / 複製酵素 / 増殖制御の情報伝達 / 増殖制御と分化 / 増殖制御とがん化 / ゲノムの分配 / ゲノム複製の終結 / ゲノム複製の開始 / HBVXタンパク / 試験管内DNA複製系 / DnaA蛋白 / 染色体の複製 / 発現調節領域 / クロマチン構造変換 / 翻訳後修飾 / クロマチンリモデリング / 染色体複製阻害 / 脱ユビキチン / クロマチン / 染色体複製 / 損傷乗り越え合成 / ゲノム不安定性疾患 / cancer / DNA damage response / recombination / genome dynamics / Rad6-Rad18 / Mgs1タンパク質 / フォークの進行阻害 / MGS1遺伝子 / Rad60遺伝子 / 複製フォーク / 染色体の不安定化 / 相同的DNA組換え / 放射線 / 複製 / DNA損傷応答 / 組換え / ゲノム動態 / ゲノム安定化 / ゲノム再編成 / DNA組換え / 酵母 / DNAモータータンパク質 / transcription / nuclear matrix / postreplication repair / DNA damage / NTH1 / XPA / 転写伸長 / チミングリコール / 細胞死 / DNA修復ネットワーク / 核マトリクス / 複製後修復 / DNA損傷トレランス / 損傷乗り越え修復 / 機能的プロテオーム / ユビキチンリガーゼ / 損傷トレランス / レーザー / ユビキチンリカーゼ / 損傷乗り越え複製 / ユビキチン化 / 熱力学 / ゲノム全体の修復 / 転写と共役した修復 / skin cancer / ultraviolet light / microinjection / trascription / 免疫グロブリン / アルキル化剤 / 基本転写 / マイクロインジェクション / photoreactivation / ultraviolet / Yeast homolog / two hybrid system / エンドヌクレアーゼ / RPA / Znフィンガー / DNA結合能 / 2ハイブリドシステム / 酵母ホモログ / αハイブリドシステム / mismatch repair / X-ray crystallography / photolyases / gene cloning / DNA結合 / モデルマウス / 活性酸素 / p53蛋白質 / X線構造解析 / 光回復酵素 / Cancer Metastasis / DNA Repair / Signal Transduction / Tumor Suppressor Genes / Oncogenes / German-Japanese Collaborative Program in Cancer Research / French-Japanese Collaborative Program in Cancer Research / International Exchange Program / がん抑制遣伝子 / がん遣伝子 / 2国間共同研究 / ヒトゲノム / がん転移 / がん細胞 / シグナル伝達 / がん抑制遺伝子 / がん遺伝子 / 複製開始蛋白 / c-myc / 細胞膜受容体 / 百日咳素素(IAP) / 蛋白質のADPリボシル化 / 百日咳毒素(IAP) / c-mycタンパク質 / 複製開始点 / 転写と複製の相関 / 発現抑制領域 / エンハンサー / 枯草菌 / 大腸菌 / イニシエータ / 制御DNA配列 / 複製開始 / プラスミド / ポリオーマウイルス / DNA合成 / 情報伝達系 / 正常細胞 / 変異株 / IAP / 情報伝達 / 増殖制御 / DNA複制開始点 / cーmycタンパク質 / 転写調節因子 / 重点領域研究 / 染色体の分離分配 / 細胞複製 / 遺伝子発現 / 姉妹染色分体交換 / チミジル酸合成酵素 / DNAポリメラーゼアルファ / 脂質代謝 / 遺伝子移入 / 染色体異常 / 分化 / 増殖因子 / ヒト遺伝子 / 遺伝子クローン化 / 哺乳類細胞 / 突然変異株 / ウィルス / 細胞組織 / 遺伝子 / 細胞・組織 / ゲノム / プロモーター / キナーゼ / 転写伸長への移行 / 転写開始 / DNA傷害 / 遺伝病 / CAK複合体 / 一本鎖DNA / キナーゼ活性 / 転写制御因子 / APエンドヌクレアーゼ / 光回復 / 塩基除去修復 / マクレオチド除去修復 / p53 / プロテアソーム / HNPCC / 酸化的DNA損傷 / チェックポイント / リボゾームRNA / 核小体 / 温度感受性 / 動物細胞 / ユビキチン / M期 / G2期 / S期 / G1期 / 遺伝子発現制御 / 遺伝情報維持 / セントロメア / 複製終結 / ゲノム分配 / 開始蛋白 / 複製起点 / ゲノム複製 / T抗原 / DNAヘリカーゼ / DNAポリメラーゼα / SV40DNA / トポイソメラ-ゼ / DNAヘリカ-ゼ / プライマ-ゼ / DNAポリメラ-ゼ / SV40ミニクロモソ-ム / 細胞複製制御因子 / 細胞分裂制御 / ゲノム分配制御 / ゲノム複製制御 / DNAアフィニティカラム / ヌクレオソ-ム / 2 / CDC28 / 自律増殖配列 / cーmycタンパク / 複製変異株 / cーMyc蛋白 / 複製蛋白 / プラスミドの複製 / C-Mycタンパク質 / c-Fosタンパク質 / 細胞増殖と分化 / サイレンサー / 遺伝子発現調節 Less
  • Research Projects

    (66 results)
  • Research Products

    (300 results)
  • Co-Researchers

    (140 People)
  •  Studies on the molecular mechanisms to regulate the resumption of stalled replication by translesion synthesis at DNA damage sites

    • Principal Investigator
      YOKOI MASAYUKI
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Risk sciences of radiation and chemicals
    • Research Institution
      Kobe University
  •  Study on rapid and hypersensitive screening of chemical genotoxin using mammalian cells defective for DNA damage-response factorsPrincipal Investigator

    • Principal Investigator
      HANAOKA Fumio
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Biological pharmacy
    • Research Institution
      Gakushuin University
  •  Molecular epidemiology studies on rare genetic disorders and pediatric cancer cohorts associated with genome instability

    • Principal Investigator
      OGI Tomoo
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Human genetics
    • Research Institution
      Nagoya University
  •  Functional analyses and development of inhibitors based on higher-order structure of translesion DNA polymerase etaPrincipal Investigator

    • Principal Investigator
      HANAOKA Fumio
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Gakushuin University
  •  Replication, repair and transcription; coupling mechanisms and chromatin dynamics for genome integrityPrincipal Investigator

    • Principal Investigator
      Hanaoka Fumio
    • Project Period (FY)
      2010 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Gakushuin University
  •  Generality of translesion synthesis coupling replication and repairPrincipal Investigator

    • Principal Investigator
      HANAOKA FUMIO
    • Project Period (FY)
      2010 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Gakushuin University
  •  Analyses of functional roles of TLS polymerases using transgenic micePrincipal Investigator

    • Principal Investigator
      HANAOKA Fumio
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biological pharmacy
    • Research Institution
      Gakushuin University
  •  Coupling of replication, repair and transcription, and their common mechanism of chromatin remodelingArea Organizer

    • Area Organizer
      HANAOKA Fumio
    • Project Period (FY)
      2010 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Research Institution
      Gakushuin University
  •  Cellular responses to inhibition of DNA replication fork progression at DNA lesionsPrincipal Investigator

    • Principal Investigator
      HANAOKA Fumio
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biological pharmacy
    • Research Institution
      Gakushuin University
      Osaka University
  •  Molecular mechanisms of translesion DNA synthesis and its involvement in carcinogenesisPrincipal Investigator

    • Principal Investigator
      HANAOKA Fumio
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Gakushuin University
      Osaka University
  •  Genetic and Epigenetic Dysregulation in Cancer

    • Principal Investigator
      NODA Tetsuo
    • Project Period (FY)
      2004 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Japanese Foundation For Cancer Research
      Tohoku University
  •  Changes in Chromatin Structure and Its Regulation in DNA RepairPrincipal Investigator

    • Principal Investigator
      HANAOKA Humio
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biological pharmacy
    • Research Institution
      Osaka University
  •  Molecular Mechanisms of Genome Homeostasis

    • Principal Investigator
      SHINAGAWA Hideo
    • Project Period (FY)
      2001 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  STUDY ON NOVEL REQULATORY MECHANISMA OF DNA REPAIRPrincipal Investigator

    • Principal Investigator
      HANAOKA Fumio
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Molecular biology
    • Research Institution
      OSAKA UNIVERSITY
  •  転写因子の欠損に起因する発がんにおける基本転写因子の役割と核内シグナル伝達機構

    • Principal Investigator
      大熊 芳明
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  DNA damage-induced cell death and DNA repair network

    • Principal Investigator
      TANAKA Kiyoji
    • Project Period (FY)
      2000 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  Studies on Molecular Mechanisms of Translesion Synthesis and CarcinogenesisPrincipal Investigator

    • Principal Investigator
      HANAOKA Fumio
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  転写因子の欠損に直接起因する発がんにおける基本転写因子TFIIEとTFIIHの役割

    • Principal Investigator
      大熊 芳明
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Osaka University
  •  転写因子の欠損に直接起因する発がんにおける基本転写因子TFIIEとTFIIHの役割

    • Principal Investigator
      大熊 芳明
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Osaka University
  •  分離核系を用いた真核細胞の転写ー修復および複製修復共役反応の解析Principal Investigator

    • Principal Investigator
      花岡 文雄
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Molecular biology
    • Research Institution
      Osaka University
  •  転写のチェックポイントとして機能する基本転写因子TFIIEの情報認識機構の研究

    • Principal Investigator
      大熊 芳明
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  転写因子の欠損に直接起因する発がんにおける基本転写因子TFIIEとTFIIHの役割

    • Principal Investigator
      大熊 芳明
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  真核細胞の転写-修復共役反応および複製-修復共役反応の無細胞系における解析Principal Investigator

    • Principal Investigator
      花岡 文雄
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Cell biology
    • Research Institution
      Osaka University
  •  Transcription-coupled repair and its deficiency

    • Principal Investigator
      TANAKA Kiyoji
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      Molecular biology
    • Research Institution
      Osaka University
  •  転写のチェックポイントとして機能する基本転写因子TFIIEの情報認識機構の研究

    • Principal Investigator
      OHKUMA Yoshiaki
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  DNA除去修復機構とその修復欠損の分子病態

    • Principal Investigator
      田中 亀代次
    • Project Period (FY)
      1996 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Osaka University
  •  Molecular Mechanisms of Genomic Instability and DNA RepairPrincipal Investigator

    • Principal Investigator
      HANAOKA Fumio
    • Project Period (FY)
      1996 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Osaka University
  •  Molecular Mechanisms of DNA Damage Recoguition and RepairPrincipal Investigator

    • Principal Investigator
      HANAOKA Fumio
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biological pharmacy
    • Research Institution
      Osaka University
  •  Search for Novel Anti-cancer Drugs Targetting DNA Replication and RepairPrincipal Investigator

    • Principal Investigator
      HANAOKA Fumio
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biological pharmacy
    • Research Institution
      Osaka University
  •  細胞複製制御の分子生物学的研究

    • Principal Investigator
      岡崎 恒子
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Nagoya University
  •  DNA複製、修復系を標的とした治療法の開発Principal Investigator

    • Principal Investigator
      花岡 文雄, SUGASAWA Kaoru
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
      The Institute of Physical and Chemical Research
  •  DNA修復欠損の分子病態Principal Investigator

    • Principal Investigator
      花岡 文雄
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Molecular biology
    • Research Institution
      Osaka University
  •  Molecular Dissection of Human DNA Excision Repair Genes

    • Principal Investigator
      TANAKA Kiyoji
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Osaka University
  •  DNAトランスアクションと遺伝情報の安定性Principal Investigator

    • Principal Investigator
      花岡 文雄
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Cell biology
    • Research Institution
      Osaka University
  •  ユビキチンサイクルが支配するがん細胞の増殖と染色体不安定化

    • Principal Investigator
      瀬野 悍二
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      National Institute of Genetics
  •  細胞周期の制御機構における癌遺伝子、癌抑制遺伝子および関連遺伝子の研究Principal Investigator

    • Principal Investigator
      花岡 文雄
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The Institute of Physical and Chemical Research
  •  Molecular Mechanism for Maintainance of Genetic Information

    • Principal Investigator
      TANAKA Kiyoji
    • Project Period (FY)
      1993 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  DNA複製反応の促進及び抑制のメカニズムと癌化

    • Principal Investigator
      吉田 松年
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Nagoya University
  •  細胞周期の制御機構における癌遺伝子・癌抑制遺伝子および関連遺伝子の研究Principal Investigator

    • Principal Investigator
      花岡 文雄
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The Institute of Physical and Chemical Research
  •  細胞複製制御の遺伝子発現Principal Investigator

    • Principal Investigator
      花岡 文雄
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
      The Institute of Physical and Chemical Research
  •  遺伝情報維持の分子機構

    • Principal Investigator
      TANAKA Kiyoji
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Institution
      Osaka University
  •  細胞周期制御のネットワーク

    • Principal Investigator
      西本 毅治
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Institution
      Kyushu University
  •  Study on Structure and Function of Mammalian DNA Replication EntymePrincipal Investigator

    • Principal Investigator
      HANAOKA Fumio
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      物質生物化学
    • Research Institution
      The Institute of Phisical and Chemical Research (RIKEN)
  •  DNA複製反応の促進及び抑制のメカニズムと癌化

    • Principal Investigator
      吉田 松年
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Nagoya University
  •  細胞周期の制御機構における癌遺伝子、癌抑制遺伝子および関連遺伝子の研究Principal Investigator

    • Principal Investigator
      花岡 文雄
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The Institute of Physical and Chemical Research
  •  細胞複製制御の分子生物学的研究

    • Principal Investigator
      岡崎 恒子
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Nagoya University
  •  細胞複製制御の遺伝子発現Principal Investigator

    • Principal Investigator
      花岡 文雄
    • Project Period (FY)
      1991 – 1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The Institute of Physical and Chemical Research
  •  Cooperation and information exchange with European countries.

    • Principal Investigator
      KUROKI Toshio
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      University of Tokyo
  •  DNA複製反応の促進及び抑制のメカニズムと癌化

    • Principal Investigator
      吉田 松年
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Nagoya University
  •  細胞周期調節に働く癌遺伝子および関連遺伝子に関する研究Principal Investigator

    • Principal Investigator
      花岡 文雄
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The Institute of Physical and Chemical Research
  •  細胞複製制御の分子生物学的研究

    • Principal Investigator
      岡崎 恒子
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Institution
      Nagoya University
  •  Involvement of Chromosome in Regulation of DNA Replication and RepairPrincipal Investigator

    • Principal Investigator
      HANAOKA Fumio
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      RIKEN (The Institute of Physical and Chemical Research)
  •  細胞周期調節に働く癌遺伝子および関連遺伝子に関する研究Principal Investigator

    • Principal Investigator
      花岡 文雄
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The Institute of Physical and Chemical Research
  •  DNA合成酵素遺伝子の構造と機能

    • Principal Investigator
      松影 昭夫
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Aichi Cancer Center Research Institute
  •  染色体の複製機構

    • Principal Investigator
      吉川 寛
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  細胞周期調節に働く癌遺伝子および関連遺伝子に関する研究Principal Investigator

    • Principal Investigator
      花岡 文雄
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  DNA合成酵素遺伝子の構造と機能

    • Principal Investigator
      松影 昭夫
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Aichi Cancer Center Research Institute
  •  細胞の増殖・分化を支配する情報伝達系ーGTP結合蛋白質とくに百日咳毒素(IAP)標的蛋白質の役割を中心にー

    • Principal Investigator
      宇井 理生
    • Project Period (FY)
      1988 – 1991
    • Research Category
      Grant-in-Aid for Specially Promoted Research
    • Research Institution
      The University of Tokyo
  •  DNA合成酵素遺伝子の構造と機能

    • Principal Investigator
      松影 昭夫
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Aichi Cancer Center Research Institute
  •  正常およびがん化細胞の増殖におけるGTP結合蛋白質の役割

    • Principal Investigator
      宇井 理生
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  細胞増殖を支配する情報伝達系ーGTP結合蛋白質の関与を中心にー

    • Principal Investigator
      宇井 理生
    • Project Period (FY)
      1987 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Biological pharmacy
    • Research Institution
      The University of Tokyo
  •  突然変異株を用いた哺乳類細胞増殖制御機構の研究Principal Investigator

    • Principal Investigator
      花岡 文雄
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      代謝生物化学
    • Research Institution
      The University of Tokyo
  •  染色体の複製機構

    • Principal Investigator
      吉川 寛
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  染色体の複製機構

    • Principal Investigator
      吉川 寛
    • Project Period (FY)
      1987 – 1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  細胞複製を制御する機能分子と染色体領域

    • Principal Investigator
      吉川 寛
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      分子遺伝学・分子生理学
    • Research Institution
      Osaka University
  •  細胞を異常増殖と癌形質発現に導く分子機構の体細胞変異株を用いた研究

    • Principal Investigator
      瀬野 悍二
    • Project Period (FY)
      1984 – 1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Research Institute for Clinical Oncology, Saitama Cancer Center

All 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2002 2000 Other

All Journal Article Presentation Book Patent

  • [Book] DNA Replication, Recombination, and Repair2016

    • Author(s)
      Hanaoka F, Sugasawa K
    • Total Pages
      555
    • Publisher
      Springer Japan
    • Data Source
      KAKENHI-PROJECT-15H04646
  • [Book] DNA Replication, Recombination, and Repair: Molecular Mechanisms and Pathology2016

    • Author(s)
      Hanaoka F, Sugasawa K
    • Total Pages
      555
    • Publisher
      Springer, Japan
    • Data Source
      KAKENHI-ORGANIZER-22131001
  • [Book] DNA Replication, Recombination, and Repair-Molecular Mechanisms and Pathology2016

    • Author(s)
      Hanaoka F, Sugasawa K
    • Total Pages
      555
    • Publisher
      Springer Japan
    • Data Source
      KAKENHI-PROJECT-15K14953
  • [Book] DNA Replication, Recombination, and Repair: Molecular Mechanisms and Pathology2016

    • Author(s)
      Hanaoka F, Sugasawa K
    • Total Pages
      555
    • Publisher
      Springer, Japan
    • Data Source
      KAKENHI-PROJECT-15K14953
  • [Book] Function of translesion DNA polymerases in genome stability2015

    • Author(s)
      Masutani C, Kanao R, Hanaoka F
    • Total Pages
      260
    • Publisher
      Research Signpost
    • Data Source
      KAKENHI-PROJECT-15H04646
  • [Journal Article] Polη, a Y-family translesion synthesis polymerase, promotes cellular tolerance of Myc-induced replication stress2018

    • Author(s)
      Kurashima Kiminori、Sekimoto Takayuki、Oda Tsukasa、Kawabata Tsuyoshi、Hanaoka Fumio、Yamashita Takayuki
    • Journal Title

      Journal of Cell Science

      Volume: 131 Issue: 12

    • DOI

      10.1242/jcs.212183

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07289, KAKENHI-PROJECT-15H04646
  • [Journal Article] Novel function of HATs and HDACs in homologous recombination through acetylation of human RAD52 at double-strand break sites2018

    • Author(s)
      Yasuda Takeshi、Kagawa Wataru、Tajima Katsushi
    • Journal Title

      PLOS Genetics

      Volume: 14 Issue: 3 Pages: 1007277-1007277

    • DOI

      10.1371/journal.pgen.1007277

    • NAID

      120006459820

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10376, KAKENHI-PROJECT-15H05333, KAKENHI-PROJECT-26281026, KAKENHI-PUBLICLY-16H01316, KAKENHI-PROJECT-17H00783, KAKENHI-PROJECT-15K14953, KAKENHI-PROJECT-17K16332, KAKENHI-PROJECT-18J13707, KAKENHI-PROJECT-16K10377, KAKENHI-PROJECT-17K19615, KAKENHI-PROJECT-15H04646, KAKENHI-PROJECT-17H01877
  • [Journal Article] Hypersensitivity of mouse embryonic fibroblast cells defective for DNA polymerases η, ι and κ to various genotoxic compounds: Its potential for application in chemical genotoxic screening2018

    • Author(s)
      Akagi Jun-ichi、Yokoi Masayuki、Cho Young-Man、Toyoda Takeshi、Ohmori Haruo、Hanaoka Fumio、Ogawa Kumiko
    • Journal Title

      DNA Repair

      Volume: 61 Pages: 76-85

    • DOI

      10.1016/j.dnarep.2017.11.006

    • NAID

      120006456929

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K00551, KAKENHI-PROJECT-16K16199, KAKENHI-PROJECT-15K14953, KAKENHI-PROJECT-15H04646
  • [Journal Article] Two mammalian homologs of yeast Rad23, HR23A and HR23B, as multifunctional proteins.2017

    • Author(s)
      Yokoi M, Hanaoka F
    • Journal Title

      Gene

      Volume: 597 Pages: 1-9

    • DOI

      10.1016/j.gene.2016.10.027

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04646, KAKENHI-PROJECT-26340028, KAKENHI-PROJECT-15K14953
  • [Journal Article] The Mcm2-7-interacting domain of human mini-chromosome maintenance 10 (Mcm10) protein is important for stable chromatin association and origin firing2017

    • Author(s)
      Izumi Masako、Mizuno Takeshi、Yanagi Ken-ichiro、Sugimura Kazuto、Okumura Katsuzumi、Imamoto Naoko、Abe Tomoko、Hanaoka Fumio
    • Journal Title

      Journal of Biological Chemistry

      Volume: 292 Issue: 31 Pages: 13008-13021

    • DOI

      10.1074/jbc.m117.779371

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-INTERNATIONAL-15K21744, KAKENHI-PLANNED-15H05929, KAKENHI-PROJECT-15K14953, KAKENHI-PROJECT-15H04646
  • [Journal Article] Direct single-molecule observations of DNA unwinding by SV40 large tumor antigen under a negative DNA superhelical state.2017

    • Author(s)
      Takahashi S, Motooka S, Kawasaki S, Kurita H, Mizuno T, Matsuura SI, Hanaoka F, Mizuno A, Oshige M, Katsura S
    • Journal Title

      J Biomol Struct Dyn

      Volume: 5 Issue: 1 Pages: 1-13

    • DOI

      10.1080/07391102.2016.1269689

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04646, KAKENHI-PROJECT-15J07154, KAKENHI-PROJECT-26390096, KAKENHI-PROJECT-15K06946, KAKENHI-PROJECT-15K14953, KAKENHI-PROJECT-16K05861
  • [Journal Article] 2,2,4-Triamino-5(2H)-oxazolone is a weak substrate for nucleotide excision repair.2016

    • Author(s)
      Kino K, Sugasawa K, Miyazawa H, Hanaoka F
    • Journal Title

      J Pharm Negative Results

      Volume: 7 Issue: 1 Pages: 42-45

    • DOI

      10.4103/0976-9234.177068

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04646, KAKENHI-PROJECT-15K14953
  • [Journal Article] The protein level of Rev1, a TLS polymerase in fission yeast, is strictly regulated during the cell cycle and after DNA damage.2015

    • Author(s)
      Uchiyama M, Terunuma J, Hanaoka F
    • Journal Title

      PLoS One

      Volume: 10 Issue: 7 Pages: e0130000-e0130000

    • DOI

      10.1371/journal.pone.0130000

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K14953, KAKENHI-ORGANIZER-22131001, KAKENHI-PROJECT-15H02654, KAKENHI-PROJECT-15H04646
  • [Journal Article] Excision of translesion synthesis errors orchestrates responses to helix-distorting DNA lesions2015

    • Author(s)
      Anastasia Tsaalbi-Shtylik, Cristina Ferrás, Bea Pauw, Giel Hendriks, Piya Temviriyanukul, Leone Carlée, Fabienne Calléja, Sandrine van Hees, Jun-Ichi Akagi, Shigenori Iwai, Fumio Hanaoka, Jacob G. Jansen, and Niels de Wind
    • Journal Title

      The Journal of Cell Biology

      Volume: 209 Issue: 1 Pages: 33-46

    • DOI

      10.1083/jcb.201408017

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25650124, KAKENHI-PROJECT-15H02654, KAKENHI-PROJECT-15H04646
  • [Journal Article] Structural basis of pyrimidine-pyrimidone (6-4) photoproduct recognition by UV-DDB in the nucleosome.2015

    • Author(s)
      Osakabe, A., Tachiwana, H., Kagawa, W., Horikoshi, N., Matsumoto, S., Hasegawa, M., Matsumoto, N., Toga, T., Yamamoto, J., Hanaoka, F., Thoma, N.H., Sugasawa, K., Iwai, S., Kurumizaka, H.
    • Journal Title

      Scientific Reports

      Volume: 5 Issue: 1 Pages: 16330-16330

    • DOI

      10.1038/srep16330

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23116008, KAKENHI-PLANNED-25116002, KAKENHI-PUBLICLY-26116521, KAKENHI-PROJECT-25250023, KAKENHI-PROJECT-26840025, KAKENHI-PROJECT-15H02654, KAKENHI-PROJECT-15H04646
  • [Journal Article] Relevance of simultaneous mono-ubiquitinations of multiple units of PCNA homo-trimers in DNA damage tolerance.2015

    • Author(s)
      Kanao R, Masuda Y, Deguchi S, Yumoto-Sugimoto M, Hanaoka F, Masutani C
    • Journal Title

      PLoS One

      Volume: 10 Issue: 2 Pages: e0118775-e0118775

    • DOI

      10.1371/journal.pone.0118775

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-22131008, KAKENHI-PROJECT-24310040, KAKENHI-PROJECT-25241011, KAKENHI-PROJECT-26740017
  • [Journal Article] Functional regulation of the DNA damage-recognition factor DDB2 by ubiquitination and interaction with xeroderma pigmentosum group C protein.2015

    • Author(s)
      Syota Matsumoto, Eric S. Fischer, Takeshi Yasuda, Naoshi Dohmae, Shigenori Iwai, Toshio Mori, Ryotaro Nishi, Ken-ichi Yoshino, Wataru Sakai, Fumio Hanaoka, Nicolas H. Thoma, Kaoru Sugasawa
    • Journal Title

      Nucleic Acids Research

      Volume: 3 Issue: 3 Pages: 1700-1713

    • DOI

      10.1093/nar/gkv038

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-13J03688, KAKENHI-PLANNED-22131008, KAKENHI-PROJECT-24241019, KAKENHI-PROJECT-26281026, KAKENHI-PROJECT-26461707, KAKENHI-PROJECT-26550042, KAKENHI-PLANNED-23116008, KAKENHI-PROJECT-26870356
  • [Journal Article] USP7 is a suppressor of PCNA ubiquitination and oxidative-stress-induced mutagenesis in human cells.2015

    • Author(s)
      Kashiwaba S, Kanao R, Masuda Y, Kusumoto-Matsuo R, Hanaoka F, Masutani C
    • Journal Title

      Cell Rep

      Volume: 13 Issue: 10 Pages: 2072-2080

    • DOI

      10.1016/j.celrep.2015.11.014

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K14953, KAKENHI-PROJECT-26740017, KAKENHI-ORGANIZER-22131001, KAKENHI-PROJECT-25241011, KAKENHI-PROJECT-15H02818, KAKENHI-PROJECT-26860310, KAKENHI-PROJECT-15H02654
  • [Journal Article] Both high-fidelity replicative and low-fidelity Y-family polymerases are involved in DNA rereplication.2015

    • Author(s)
      Sekimoto T, Oda T, Kurashima K, Hanaoka F, Yamashita T
    • Journal Title

      Mol Cell Biol

      Volume: 35 Issue: 4 Pages: 699-715

    • DOI

      10.1128/mcb.01153-14

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-22131008, KAKENHI-PROJECT-24700952, KAKENHI-PUBLICLY-25131703
  • [Journal Article] USP7 is a suppressor of PCNA ubiquitination and oxidative-stress-induced mutagenesis in human cells.2015

    • Author(s)
      Kashiwaba S, Kanao R, Masuda Y, Kusumoto-Matsuo R, Hanaoka F, Masutani C
    • Journal Title

      Cell Rep

      Volume: 13 Pages: 2072-2080

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04646
  • [Journal Article] Different types of interaction between PCNA and PIP boxes contribute to distinct cellular functions of Y-family DNA polymerases.2015

    • Author(s)
      Masuda Y, Kanao R, Kaji K, Ohmori H, Hanaoka F, Masutani C
    • Journal Title

      Nucleic Acids Res

      Volume: 43 Issue: 16 Pages: 7898-7910

    • DOI

      10.1093/nar/gkv712

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K14953, KAKENHI-PROJECT-26740017, KAKENHI-ORGANIZER-22131001, KAKENHI-PROJECT-25241011, KAKENHI-PROJECT-15H02818, KAKENHI-PROJECT-15H02654, KAKENHI-PROJECT-15H04646
  • [Journal Article] UV-induced mutations in epidermal cells of mice defective in DNA polymerase η and/or ι2015

    • Author(s)
      Kanao R, Yokoi M, Ohkumo T, Sakurai Y, Dotsu K, Kura S, Nakatsu Y, Tsuzuki T, Masutani C, Hanaoka F
    • Journal Title

      DNA Repair (Amsterdam)

      Volume: S1568-7864(15) Pages: 00042-7

    • DOI

      10.1016/j.dnarep.2015.02.006

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25241011, KAKENHI-PROJECT-26340028, KAKENHI-PROJECT-26740017, KAKENHI-PROJECT-26340025, KAKENHI-PROJECT-15K14953, KAKENHI-ORGANIZER-22131001, KAKENHI-PUBLICLY-15H00897, KAKENHI-PLANNED-24108009, KAKENHI-PROJECT-15H02654, KAKENHI-PROJECT-15H04646
  • [Journal Article] SUMOylation of xeroderma pigmentosum group C protein regulates DNA damage recognition during nucleotide excision repair2015

    • Author(s)
      Akita M
    • Journal Title

      Sci. Rep.

      Volume: 5 Issue: 1 Pages: 10984-10984

    • DOI

      10.1038/srep10984

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K12203, KAKENHI-PROJECT-15K12220, KAKENHI-PROJECT-15K14953, KAKENHI-PROJECT-26550042, KAKENHI-ORGANIZER-22131001, KAKENHI-PLANNED-23116008, KAKENHI-PUBLICLY-26116517, KAKENHI-PROJECT-26870356, KAKENHI-PROJECT-26281020, KAKENHI-PROJECT-15H04646
  • [Journal Article] Remarkable induction of UV-signature mutations at the 3'-cytosine of dipyrimidine sites except at 5'-TCG-3' in the UVB-exposed skin epidermis of xeroderma pigmentosum variant model mice.2014

    • Author(s)
      Ikehata H, Chang Y, Yokoi M, Yamamoto M, Hanaoka F
    • Journal Title

      DNA Repair

      Volume: 22 Pages: 112-122

    • DOI

      10.1016/j.dnarep.2014.07.012

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-22131008, KAKENHI-PROJECT-24310036, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-26340028
  • [Journal Article] Shingosine, a modulator of human translesion DNA polymerase activity.2014

    • Author(s)
      Kamath-Loeb AS, Balakrishna S, Whittington D, Shen JC, Emond MJ, Okabe T, Masutani C, Hanaoka F, Nishimura S, Loeb LA
    • Journal Title

      J Biol Chem

      Volume: 289 Issue: 31 Pages: 21663-21672

    • DOI

      10.1074/jbc.m114.570242

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-22131008, KAKENHI-PROJECT-25241011
  • [Journal Article] Guanine-5-carboxylcytosine base pairs mimic mismatches during DNA replication.2014

    • Author(s)
      Shibutani T, Ito S, Toda M, Kanao R, Collins LB, Shibata M, Urabe M, Koseki H, Masuda Y, Swenberg JA, Masutani C, Hanaoka F, Iwai S, Kuraoka I
    • Journal Title

      Scientific Reports

      Volume: 4 Issue: 1 Pages: 5220-5220

    • DOI

      10.1038/srep05220

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-22131008, KAKENHI-PROJECT-24310040, KAKENHI-PROJECT-25241011, KAKENHI-PROJECT-25281018, KAKENHI-PROJECT-26650006, KAKENHI-PROJECT-26740017
  • [Journal Article] A cyclobutane thymine-N4-methylcytosine dimer is resistant to hydrolysis but strongly blocls DNA synthesis.2014

    • Author(s)
      Yamamoto J, Oyama T, Kunishi T, Masutani C, Hanaoka F, Iwai S
    • Journal Title

      Nucleic Acids Res

      Volume: 42 Issue: 3 Pages: 2075-2084

    • DOI

      10.1093/nar/gkt1039

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-ORGANIZER-22131001, KAKENHI-PLANNED-22131008, KAKENHI-PROJECT-25241011, KAKENHI-PROJECT-25870400, KAKENHI-PROJECT-22249005
  • [Journal Article] Mechanism of somatic hypermutation at the WA motif by human DNA polymerase eta.2013

    • Author(s)
      Zhao Y, Gregory MT, Biertümpfel C, Hua YJ, Hanaoka F, Yang W
    • Journal Title

      Proc Natl Acad Sci USA

      Volume: 110 Issue: 20 Pages: 8146-8151

    • DOI

      10.1073/pnas.1303126110

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-ORGANIZER-22131001, KAKENHI-PLANNED-22131008, KAKENHI-PROJECT-22249005
  • [Journal Article] Trapping DNA replication origins from the human genome.2013

    • Author(s)
      Eki T, Murakami Y, Hanaoka F
    • Journal Title

      Genes (Basel)

      Volume: 4 Issue: 2 Pages: 198-225

    • DOI

      10.3390/genes4020198

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-ORGANIZER-22131001, KAKENHI-PLANNED-22131008, KAKENHI-PROJECT-23590074, KAKENHI-PROJECT-22249005
  • [Journal Article] Trapping DNA replication origins from the human genome2013

    • Author(s)
      Eki, T., Murakami, Y., and Hanaoka, F
    • Journal Title

      Genes (Basel)

      Volume: 4 Pages: 198-225

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249005
  • [Journal Article] Structure-function analysis of the EF-hand protein centrin-2 for its intracellular localization and nucleotide excision repair.2013

    • Author(s)
      Nishi R, Sakai W, Tone D, Hanaoka F, Sugasawa K
    • Journal Title

      Nucleic Acids Res

      Volume: 41 Issue: 14 Pages: 6917-6929

    • DOI

      10.1093/nar/gkt434

    • NAID

      120005621886

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-ORGANIZER-22131001, KAKENHI-PLANNED-22131008, KAKENHI-PLANNED-23116008, KAKENHI-PROJECT-24241019, KAKENHI-PROJECT-22249005
  • [Journal Article] Identification of new scavengers for hydroxyl radicals and superoxide dismutase by utilizing ultraviolet A photoreaction of 8-methoxypsoralen and a variety of mutants of Escherichia coli : implications on certain diseases of DNA repair deficiency2012

    • Author(s)
      Ahmad, S., Yokoi, M., and Hanaoka, F
    • Journal Title

      J. Photochem. Photobiol. B.

      Volume: 116 Pages: 30-36

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249005
  • [Journal Article] A DNA oligomer containing 2,2,4-triamino-5(2H)-oxazolone is incised by human NEIL1 and NTH1.2012

    • Author(s)
      Kino K
    • Journal Title

      Mutat Res

      Volume: 734 Issue: 1-2 Pages: 73-77

    • DOI

      10.1016/j.mrfmmm.2012.03.007

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-22131001, KAKENHI-PLANNED-22131008, KAKENHI-PROJECT-23510069, KAKENHI-PROJECT-22249005
  • [Journal Article] Analysis of mice deficient in both REV1 catalytic activity and POLH reveals an unexpected role for POLH in the generation of C to G and G to C transversions during Ig gene hypermutation.2012

    • Author(s)
      Kano C
    • Journal Title

      Int Immunol

      Volume: 24 Issue: 3 Pages: 169-174

    • DOI

      10.1093/intimm/dxr109

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-22131001, KAKENHI-PLANNED-22131008, KAKENHI-PROJECT-22590445, KAKENHI-PROJECT-22249005
  • [Journal Article] The vital role of polζand REV1 in mutagenic, but not correct, DNA synthesis across benzo[a]pyrene-dG and the recruitment of polζby REV1 to a replication-stalled site2012

    • Author(s)
      Hashimoto, K., Cho, Y., Yang, I. Y., Akagi, J., Ohashi, E., Tateishi, S., de Wind, N., Hanaoka, F., Ohmori, H., and Moriya, M
    • Journal Title

      J. Biol. Chem.

      Volume: 96 Pages: 9613-9622

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249005
  • [Journal Article] Stalled Polη at its cognate substrate initiates an alternative translesion synthesis pathway via interaction with REV1.2012

    • Author(s)
      Ito W
    • Journal Title

      Genes Cells

      Volume: 17 Issue: 2 Pages: 98-108

    • DOI

      10.1111/j.1365-2443.2011.01576.x

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-22131001, KAKENHI-PLANNED-22131008, KAKENHI-PROJECT-22710059, KAKENHI-PROJECT-22249005
  • [Journal Article] Structural basis of human DNA polymerase eta-mediated chemoresistance to cisplatin.2012

    • Author(s)
      Zhao Y
    • Journal Title

      Proc. Natl. Acad. Sci. USA

      Volume: 109 Issue: 19 Pages: 7269-7274

    • DOI

      10.1073/pnas.1202681109

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-22131001, KAKENHI-PLANNED-22131008, KAKENHI-PROJECT-22249005
  • [Journal Article] Photosensitized [2 + 2] cycloaddition on N-acetylated cytosine affords stereoselective formation of cyclobutane pyrimidine dimer2011

    • Author(s)
      Yamamoto, J., Nishiguchi, K., Manabe, K., Masutani, C., Hanaoka, F., and Iwai, S
    • Journal Title

      Nucleic Acid Res

      Volume: 39 Issue: 3 Pages: 1165-1175

    • DOI

      10.1093/nar/gkq855

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249005
  • [Journal Article] Molecular chaperone Hsp90 regulates REV1-mediated mutagenesis.2011

    • Author(s)
      Pozo FM
    • Journal Title

      Mol Cell Biol

      Volume: 31 Issue: 16 Pages: 3396-3409

    • DOI

      10.1128/mcb.05117-11

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-22131001, KAKENHI-PLANNED-22131008, KAKENHI-PROJECT-22590264, KAKENHI-PROJECT-22790306, KAKENHI-PUBLICLY-23131503, KAKENHI-PROJECT-23501257, KAKENHI-PROJECT-22249005
  • [Journal Article] NBS1 recruits RAD18 via aRAD6-like domain and regulates Polη-dependent translesion DNA synthesis2011

    • Author(s)
      Yanagihara H, Kobayashi J, Tateishi S, Kato A, Matsuura S, Tauchi H, Yamada K, Takezawa J, Sugasawa K, Masutani C, Hanaoka F, Weemaes CM, Mori T, Zou L, Komatsu K.
    • Journal Title

      Mol Cell

      Volume: 43 Issue: 5 Pages: 788-797

    • DOI

      10.1016/j.molcel.2011.07.026

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21310035, KAKENHI-PUBLICLY-22019026, KAKENHI-ORGANIZER-22131001, KAKENHI-PLANNED-22131008, KAKENHI-PROJECT-22651018, KAKENHI-PROJECT-22710053, KAKENHI-PROJECT-23241021, KAKENHI-PROJECT-23651045, KAKENHI-PROJECT-22249005
  • [Journal Article] Genetic analysis using a mouse cell cycle mutant identifies magoh as a novel gene involved in Cdk regulation2011

    • Author(s)
      Inaki, M., Kato, D., Utsugi, T., Onoda, F., Hanaoka, F., and Murakami, Y
    • Journal Title

      Genes Cells

      Volume: 16 Issue: 2 Pages: 166-178

    • DOI

      10.1111/j.1365-2443.2010.01479.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249005
  • [Journal Article] Hst3 and Hst4 histone deacetylases regulate replicative lifespan by preventing genome instability in Saccharomyces cerevisiae2011

    • Author(s)
      Hachinohe, M., Hanaoka, F., and Masumoto, H
    • Journal Title

      Genes Cells

      Volume: 16 Issue: 4 Pages: 467-477

    • DOI

      10.1111/j.1365-2443.2011.01493.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249005
  • [Journal Article] The molecular basis of CRL4DDB2/CSA ubiquitin ligase architecture, targeting, and activation2011

    • Author(s)
      Fischer, E.S., et al
    • Journal Title

      Cell

      Volume: 147 Issue: 5 Pages: 1024-1039

    • DOI

      10.1016/j.cell.2011.10.035

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20241013, KAKENHI-PROJECT-21510055, KAKENHI-ORGANIZER-22131001, KAKENHI-PLANNED-22131008, KAKENHI-PLANNED-23116008, KAKENHI-PROJECT-23651050, KAKENHI-PROJECT-22249005
  • [Journal Article] Structure and mechanism of human DNA polymeraseη.2010

    • Author(s)
      Biertampfel, C., Zhao, Y., Kondo, Y., Ramon-Maiques, S., Gregory, M., Lee, J.Y., Masutani, C., Lehmann, A.R., Hanaoka, F., Yang, W.
    • Journal Title

      Nature 465

      Pages: 1044-1049

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Journal Article] Structure and mechanism of human DNA polymeraseη2010

    • Author(s)
      Biertümpfel, C., Zhao, Y., Kondo, Y., Ramon-Maiques, S., Gregory, M., Lee, J. Y., Masutani, C., Lehmann, A. R., Hanaoka, F., and Yang, W
    • Journal Title

      Nature

      Volume: 465 Issue: 7301 Pages: 1044-1049

    • DOI

      10.1038/nature09196

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249005
  • [Journal Article] The molecular chaperone Hsp90 regulates accumulation of DNA polymerase eta at replication stalling sites in UV-irradiated cells.2010

    • Author(s)
      Sekimoto, T., Oda, T., Pozo, F.M., Murakumo, Y., Masutani, C., Hanaoka, F., Yamaashita, T.
    • Journal Title

      Hal.Cell 37

      Pages: 79-89

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Journal Article] Polymerization by DNA polymerase eta is blocked by cisdiamminedichloroplatinum( II) 1, 3-d(GpTpG) cross-link: implications for cytotoxic effects in nucleotide excision repair-negative tumor cells.2010

    • Author(s)
      Chijiwa, S., Masutani, C., Hanaoka, F., Iwai, S., Kuraoka, I
    • Journal Title

      Carcinogenesis 31

      Pages: 388-393

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Journal Article] Structure and mutagenesis studies of the C-terminal region of licensing factor Cdt1 enable the identification of key residues for binding to replicative helicase Mcm proteins.2010

    • Author(s)
      Jee, J., Mizuno, T., Kamada, K., Tochio, H., Chiba, Y., Yanagi, K.I., Yasuda, G., Hiroaki, H., Hanaoka, F., Shirakawa, M.
    • Journal Title

      J. Biol. Chem 285

      Pages: 15931-15940

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Journal Article] Simultaneous disruption of two DNA polymerases, Polηand Polζin avian DT40 cells unmasks the role of Polηin celluler response to various DNA lesions2010

    • Author(s)
      Hirota, K., Sonoda, E., Kawamoto, T., Motegi, A., Masutani, C., Hanaoka, F., Szuts, D., Iwai, S., Sale, J. E., Lehmann, A., and Takeda, S
    • Journal Title

      PLoS Genet

      Volume: 6, pii Issue: 10 Pages: e1001151-e1001151

    • DOI

      10.1371/journal.pgen.1001151

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249005
  • [Journal Article] Stimulation of DNA glycosylase activities by XPC protein complex : roles of protein-protein interactions2010

    • Author(s)
      Shimizu, Y., Uchimura, Y., Dohmae, N., Saitoh, H., Hanaoka, F., and Sugasawa, K
    • Journal Title

      J. Nucleic Acids pii

      Volume: 2010 Issue: 1 Pages: 805698-805698

    • DOI

      10.4061/2010/805698

    • NAID

      120003202349

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249005
  • [Journal Article] The molecular chaperone Hsp90 regulates accumulation of DNA polymerase eta at replication stalling sites in UV-irradiated cells.2010

    • Author(s)
      Sekimoto, T., Oda, T., Pozo, F.M., Murakumo, Y., Masutani, C., Hanaoka, F., Yamashita, T
    • Journal Title

      Mol. Cell 37

      Pages: 79-89

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Journal Article] Structure and mechanism of human DNA polymeraseη2010

    • Author(s)
      Biertumpfel, C., Zhao, Y., Kondo, Y., Ramon-Maiques, S., Gregory, M., Lee, J.Y., Masutani, C., Lehmann, A.R., Hanaoka, F., Yang, W
    • Journal Title

      Nature 465

      Pages: 44-1049

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Journal Article] Critical amino acids in human DNA polymerases eta and kappa involved in erroneous incorporation of oxidized nucleotides.2010

    • Author(s)
      Katafuchi, A., Sassa, A., Niimi, N., Gruz, P. Fujimoto, H., Masutani, C., Hanaoka, F., Ohta, T., Nohmi, T.
    • Journal Title

      Nucleic Acids Res 38

      Pages: 859-867

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Journal Article] Characterization of a Y-family DNA polymeraseηfrom the eukaryotic thermophile Alvinella pompejana2010

    • Author(s)
      Kashiwagi, S., Kuraoka, I., Fujiwara, Y., Hitomi, K., Cheng, Q. J., Shin, D. S., Masutani, C., Tainer, J. A., Hanaoka, F., and Iwai, S
    • Journal Title

      J. Nucleic Acids pii

      Volume: 2010 Issue: 1 Pages: 701472-701472

    • DOI

      10.4061/2010/701472

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22249005
  • [Journal Article] Structure and mutagenesis studies of the C-terminal region of licensing factor Cdt1 enable to identify the key residues for binding to replicative helicase Mcm proteins2010

    • Author(s)
      Jee, J.-G., Mizuno, T., Kamada, K., Tochio, T., Chiba, Y., Yanagi, K., Yasuda, G., Hiroaki, H., Hanaoka, F. and Shirakawa, M
    • Journal Title

      Journal of Biological Chemistry

      Volume: vol.285(21) Issue: 21 Pages: 15931-40

    • DOI

      10.1074/jbc.m109.075333

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21247013, KAKENHI-PROJECT-22249005
  • [Journal Article] Structure and mechanism of human DNA polymeraseη2010

    • Author(s)
      C. Biertumpfel, Y. Zhao, Y. Kondo, S. Ramon-Maiques, M. Gregory, J.Y. Lee, C. Masutani, A.R. Lehmann, F. Hanaoka, W. Yang
    • Journal Title

      Nature 465

      Pages: 1044-1049

    • Data Source
      KAKENHI-PROJECT-16059101
  • [Journal Article] Simultaneous disruption of two DNA polymerases, Polη and Polζ, in Avian DT40 cells unmasks the role of Polη in cellular response to various DNA lesions.2010

    • Author(s)
      Hirota, K., Sonoda, E., Kawamoto, T., Motegi, A., Masutani, C., Hanaoka, F., Szuts, D., Iwai, S., Sale, J.E., Lehmann, A., Takeda, S.
    • Journal Title

      PLoS.Genet. 6

    • NAID

      120002661519

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Journal Article] The chromosomal association of condensin II is required by a noncatalytic function of PP2A.2009

    • Author(s)
      Takemoto, A., Maeshima, K., Ikehara, T., Yamaguchi, K., Murayama, A., Imamura, S., Imamoto, N., Yokoyama, S., Hirano, T., Watanabe, Y., Hanaoka, F., Yanagisawa, J., Kimura, K
    • Journal Title

      Nat. Struct. Mol. Biol 16

      Pages: 1302-1308

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Journal Article] A nobel interaction between human DNA polymerase eta and MutL alpha. Biochem. Biophys.2009

    • Author(s)
      Kanao, R., Hanaoka, F., Masutani, C.
    • Journal Title

      Biochem. Biophys. Res. Commun 389

      Pages: 40-45

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Journal Article] Cyclin A-Cdk1 regulates the origin firing program in mammalian cells.2009

    • Author(s)
      Katsuno, Y., Suzuki, A., Sugimura, K., Okumura, K., Zineldeen, D.H., Shimada, M., Niida, H., Mizuno, T., Hanaoka, F., Nakanishi, M.
    • Journal Title

      Proc. Natl. Acad. Sci. USA 106

      Pages: 3184-3189

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Journal Article] Interaction with DNA polymerase eta is required for nuclear accumulation of REV1 and suppression of spontaneous mutations in human cells.2009

    • Author(s)
      Akagi, J., Masutani, C., Kataoka, Y., Kan, T., Ohashi, E., Mori, T., Ohmori, H., Hanaoka, F.
    • Journal Title

      DNA Repair 8

      Pages: 585-599

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Journal Article] Aberrant DNA polymerase alpha is excluded from the nucleus by defective import and degradation in the nucleus.2009

    • Author(s)
      Eichinger, C.S., Mizuno, T., Mizuno, K., Miyake, Y., Yanagi, K., Imamoto, N., Hanaoka, F.
    • Journal Title

      J.Biol.Chem. 284

      Pages: 30604-30614

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Journal Article] Interaction with DNA polymerase eta is required for nuclear accumulation of REV1 and suppression of spontaneous mutations in human cells.2009

    • Author(s)
      Akagi, J., Masutani, C., Kataoka, Y., Kan, T., Ohashi, E., Mori, T., Ohmori, H., Hanaoka, F.
    • Journal Title

      DM Repair 8

      Pages: 585-599

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Journal Article] The chromosomal association of condensin II is required by a noncatalytic function of PP2A.2009

    • Author(s)
      Takemoto, A., Maeshima, K., Ikehara, T., Yamaguchi, K., Murayama, A., Imamura, S., lamamoto, N., Yokoyama, S., Hirano, T., Watanabe, Y., Hanaoka, F., Yanagisawa, J., Kimura, K.
    • Journal Title

      Nat.Struct.Aiol.Biol. 16

      Pages: 1302-1308

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Journal Article] Translesional DNA synthesis through a C8-guanyl adduct of 2-amino-1-methyl-6-phenylimidazo[4, 5-b]pyridine (PhIP) in vitro: REV1 inserts dC opposite the lesion, and DNA polymerase kappa potentially catalyzes extension reaction from the 3'-dC terminus.2009

    • Author(s)
      Fukuda, H., Takamura-Enya, T., Masuda, Y., Nohmi, T., Seki, C., Kamiya, K., Sugimura, T., Masutani, C., Hanaoka, F., Nakagama, H.
    • Journal Title

      J. Biol. Chem 284

      Pages: 25585-25592

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Journal Article] Penicilliols A and B, novel inhibitors specific to mammalian Y-family DNA polymerases.2009

    • Author(s)
      Kimura, T., Takeuchi, T., Kumamoto-Yonezawa, Y., Ohashi, E., Ohmori, H., Masutani, C., Hanaoka, F., Sugawara, F., Yoshida, H., Mizushina, Y.
    • Journal Title

      Bioorg. Med. Chem 17

      Pages: 1811-1816

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Journal Article] Cyclin A-Cdkl regulates the origin firing program in mammalian cells.2009

    • Author(s)
      Katsuno, Y., Suzuki, A., Sugimura, K., Okumura, K., Zineldeen, D.H., Shimada, M., Niida, H., Mizuno, T., Hanaoka, F., Nakanishi, M.
    • Journal Title

      Proc.Natl.Acad Sci.USA 106

      Pages: 3184-3189

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Journal Article] Two-step recognition of DNA damage for mammalian nucleotide excision repair : Directional binding of the XPC complex and DNA strand scanning.2009

    • Author(s)
      Sugasawa, K., Akagi, J., Nishi, R., Iwai, S., Hanaoka, F.
    • Journal Title

      Alai.Cell 36

      Pages: 642-653

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Journal Article] Two-step recognition of DNA damage for mammalian nucleotide excision repair: Directional binding of the XPC complex and DNA strand scanning.2009

    • Author(s)
      Sugasawa, K., Akagi, J., Nishi, R., Iwai, S., Hanaoka, F.
    • Journal Title

      Mol. Cell 36

      Pages: 642-653

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Journal Article] Central forkhead domain of human TFIIE beta plays a primary role in binding double-stranded DNA at transcription initiation.2009

    • Author(s)
      Tanaka, A., Watanabe, T., Iida, Y., Hanaoka, F., Ohkuma Y.
    • Journal Title

      Genes Cells 14

      Pages: 395-405

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Journal Article] Eukaryotic DNA polymerases alpha, beta and epsilon incorporate guanine opposite 2, 2, 4-triamino-5(2H)-oxazolone.2009

    • Author(s)
      Kino, K., Sugasawa, K., Mizuno, T., Bando, T., Sugiyama, H., Akita, M., Miyazawa, H., Hanaoka, F.
    • Journal Title

      Chembiochem 10

      Pages: 2613-2616

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Journal Article] UV-DDB-dependent regulation of nucleotide excision repair kinetics in living cells.2009

    • Author(s)
      Nishi, R., Alekseev, S., Dinant, C., Hoogstraten, D., Houtsmuller, A.B., Hoeijmakers, J.H., Vermeulen, W., Hanaoka, F., Sugasawa, K.
    • Journal Title

      DNA Repair 8

      Pages: 767-776

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Journal Article] Specificity of mutations induced by incorporation of oxidized dNTPs into DNA by human DNA polymerase eta.2008

    • Author(s)
      Hidaka, K., Yamada, M., Kamiya, H., Masutani, C., Harashima, H., Hanaoka, F., Nohmi, T.
    • Journal Title

      DNA Repair 7

      Pages: 497-506

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Journal Article] Genetic analysis reveals an intrinsic property of the germinal center B cells to generate A:T mutations.2008

    • Author(s)
      Ouchida, R., Ukai, A., Mori, H., Kawamura, K., Dolle, M.E.T., Tagawa, M., Sakamoto, A., Tokuhisa, T., Yokosuka, T., Saito, T., Yokoi, M., Hanaoka, F., Vijg, J., Wang, J.Y.
    • Journal Title

      DNA Repair 7

      Pages: 1392-1398

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Journal Article] Novel DNA microarray system for analysis of nascent mRNAs.2008

    • Author(s)
      Ohtsu, M., Kawate, M., Fukuoka, M., Gunji, W., Hanaoka, F., Utsugi, T., Onoda, F., Murakami, Y.
    • Journal Title

      DNA Res 15

      Pages: 241-251

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Journal Article] Recognition of forked and single-stranded DNA structures by human RAD18 complexed with RAD6B protein triggers its recruitment to stalled replication forks.2008

    • Author(s)
      Tsuji, Y., Watanabe, K., Araki, K., Shinohara, M., Yamagata, Y., Tsurimoto, T., Hanaoka, F., Yamamura, K., Yamaizumi, M., Tateishi, S.
    • Journal Title

      Genes Cells 13

      Pages: 343-354

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Journal Article] Schizosaccharomyces pombe Ddb1 recruits substrate-specific adaptor proteins through a novel protein motif, the DDB-box.2008

    • Author(s)
      Fukumoto, Y., Dohmae, N., Hanaoka, F.
    • Journal Title

      Mol. Cell. Biol 28

      Pages: 6746-6756

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Journal Article] DNA polymerase eta is a limiting factor for A:T mutations in Ig genes and contributes to antibody affinity maturation.2008

    • Author(s)
      Masuda, K., Ouchida, R., Yokoi, M., Hanaoka, F., Azuma, T., Wang, J.Y.
    • Journal Title

      Eur. J. Immunol 38

      Pages: 796-2805

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Journal Article] Miscoding properties of 2'-deoxyinosine, a nitric oxide-derived DNA adduct, during translesion synthesis catalyzed by human DNA polymerases.2008

    • Author(s)
      Yasui, M., Suenaga, E., Koyama, N., Masutani, C., Hanaoka, F., Gruz, P., Shibutani, S., Nohmi, T., Hayashi, M., Honma, M.
    • Journal Title

      J. Mol. Biol 377

      Pages: 1015-1023

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Journal Article] Mutagenic radioadaptation in a human lymphoblastoid cell line.2008

    • Author(s)
      Yatagai, F., Umebayashi, Y., Homma, M., Sugasawa, K., Takayama, Y., Hanaoka, F.
    • Journal Title

      Mutat. Res 638

      Pages: 48-55

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Journal Article] Schizosaccharomyees pombe Ddbl recruits substrate-specific adaptor proteins through a novel protein motif, the DDB-box.2008

    • Author(s)
      Fukumoto, Y., Dohmae, N., Hanaoka, F.
    • Journal Title

      Mol.Cell.Biol. 28

      Pages: 6746-6756

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Journal Article] Reevaluation of the role of DNA polymerase theta in somatic hypermutation of immunoglobulin genes.2008

    • Author(s)
      Martomo, S.A., Saribasak, H., Yokoi, M., Hanaoka, F., Gearhart, P.J.
    • Journal Title

      DNA Repair 7

      Pages: 1603-1608

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Journal Article] A novel class of temperature-sensitive mutants generated by RNAi-r. Biochem.2008

    • Author(s)
      Inaki, M., Utsugi, T., Onoda, F., Hanaoka, F., Murakami, Y.
    • Journal Title

      Biophys. Res. Commun 365

      Pages: 472-477

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Journal Article] Analysis of the role of Aurora B on the chromosomal targeting of condensin I.2007

    • Author(s)
      Takemoto, A., Murayama, A., Katano, M., Urano, T., Furukawa, K., Yokoyama, S., Yanagisawa, J., Hanaoka, F., Kimura, K.
    • Journal Title

      Nucleic Acids Res 35

      Pages: 2403-2412

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Journal Article] In vivo destabilization and functional defects of the xeroderma pigmentosum C protein caused by a pathogenic missense mutation.2007

    • Author(s)
      Yasuda, G., Nishi, R., Watanabe, E., Mori, T., Iwai, S., Orioli, D., Stefanini, M., Hanaoka, F., Sugasawa, K.
    • Journal Title

      Mol. Cell. Biol 27

      Pages: 6606-6614

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Journal Article] Rad54 dissociates homologous recombination intermediates by branch migration.2007

    • Author(s)
      Bugreev, D.V., Hanaoka, F., Mazin, A.V.
    • Journal Title

      Nat. Struct. Mol. Biol 14

      Pages: 746-753

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Journal Article] A genome-wide survey and systematic RNAi-based characterization of helicase-like genes in Caenorhabditis elegans.2007

    • Author(s)
      Eki, T., Ishihara, T., Katsura, I., Hanaoka, F.
    • Journal Title

      DNA Res 14

      Pages: 183-199

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Journal Article] A second PCNA loader complex, Ctf18-RFC, stimulates DNA polymeraseηactivity.2007

    • Author(s)
      Shiomi, Y., Masutani, C., Hanaoka, F., Kimura, H., Tsurimoto, T.
    • Journal Title

      J. Biol. Chem 282

      Pages: 20906-20914

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Journal Article] Dicer-related drh-3 gene functions in germ-line development by maintenance of chromosomal integrity in Caenorhabditis elegans.2007

    • Author(s)
      Nakamura, M., Ando, R., Nakazawa, T., Yudazono, T., Tsutsumi, N., Hatanaka, N., Ohgake, T., Hanaoka, F., Eki, T.
    • Journal Title

      Genes Cells 12

      Pages: 997-1010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Journal Article] Sensing of DNA damage by XPC/Rad4: 0ne protein for many lesions.2007

    • Author(s)
      Sugasawa, K.&Hanaoka, F.
    • Journal Title

      Nat. Struct. Mol. Biol. 14

      Pages: 887-888

    • Data Source
      KAKENHI-PROJECT-19209003
  • [Journal Article] Structure of the human GINS complex and its assembly and functional interface in replication initiation.2007

    • Author(s)
      K. Kamada, F. Hanaoka, et. al. (total 5, last)
    • Journal Title

      Nature Struct. Mol. Biol. 14

      Pages: 388-396

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16059101
  • [Journal Article] 2-Hydroxy-dATP enhances A:T→C:G mutations caused by 8-hydroxy-dGTP by suppressing its degradation upon replication in a HeLa extract.2007

    • Author(s)
      Satou, K., Kasai, H., Masutani, C., Hanaoka, F., Harashima, H., Kamiya, H.
    • Journal Title

      Biochemistry 46

      Pages: 6639-6646

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Journal Article] Rad54 dissociates homologous recombination intermediates by branch migration.2007

    • Author(s)
      Bugreev, D.V., Hanaoka, F., Mazin, A.V.
    • Journal Title

      Nat.Struct.Mol.Biol. 14

      Pages: 746-753

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Journal Article] Mutational analyses of a single-stranded telomeric DNA binding domain of fission yeast pot1: conflict with x-ray crystallographic structure.2007

    • Author(s)
      Torigoe, H., Dohmae, N., Hanaoka, F., Furukawa, A.
    • Journal Title

      Biosci. Biotechnol. Biochem 71

      Pages: 481-490

    • NAID

      10027511703

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Journal Article] Efficient and erroneous incorporation of oxidized DNA precursors by human DNA polymeraseη.2007

    • Author(s)
      Shimizu, M., Gruz, P., Kamiya, H., Masutani, C., Xu, Y., Usui, Y., Sugiyama, H., Harashima, H., Hanaoka, F., Nohmi, T.
    • Journal Title

      Biochemistry 46

      Pages: 5515-5522

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Journal Article] In vivo destabilization and functional defects of the xeroderma pigmentosum C protein caused by a pathogenic missense mutation.2007

    • Author(s)
      Yasuda, G., Nishi, R., Watanabe, E., Mori, T., Iwai, S., Orioli, D., Stefanini, M., Hanaoka, F., Sugasawa, K.
    • Journal Title

      Mol.Cell.Biol. 27

      Pages: 6606-6614

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Journal Article] Structure of the human GINS complex and its assembly and functional interface in replication initiation.2007

    • Author(s)
      Kamada, K., Kubota, Y., Arata, T., Shindo, Y., Hanaoka, F.
    • Journal Title

      Nature Struct.Mot.Biol. 14

      Pages: 388-396

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Journal Article] A genome-wide survey and systematic RNAi-based characterization of helicase-like genes in Caenorhabditis elegans.2007

    • Author(s)
      Eki, T., Ishihara, T., Katsura, I., Hanaoka, F.
    • Journal Title

      DNA Res. 14

      Pages: 183-199

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Journal Article] DNA polymeraseηand・function in the same genetic pathway to generate mutations at A/T during somatic hypermutation of Ig genes.2007

    • Author(s)
      Masuda, K., Ouchida, R., Hikida, M., Kurosaki, T., Yokoi, M., Masutani, C., Seki, M., Wood, R.D., Hanaoka, F., O-Wang, J.
    • Journal Title

      J. Biol. Chem 282

      Pages: 17387-17394

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Journal Article] A kinase subunit of the human mediator complex, CDK8, positively regulates transcriptional activation.2007

    • Author(s)
      Furumoto, T., Tanaka, A., Ito, M., Malik, S., Hirose, Y., Hanaoka, F., Ohkuma, Y.
    • Journal Title

      Genes Cells 12

      Pages: 119-132

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Journal Article] Structure of the human GINS complex and its assembly and functional interface in replication initiation. Nature Struct.2007

    • Author(s)
      Kamada, K., Kubota, Y., Arata, T., Shindo, Y., Hanaoka, F.
    • Journal Title

      Nature Struct. Mol. Biol 14

      Pages: 388-396

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Journal Article] A human DNA polymerase eta complex containing Rad18, Rad6 and Revl ; proteomic analysis and targeting of the complex to the chromatin-bound fraction of cells undergoing replication fork arrest.2006

    • Author(s)
      Yuasa, M.S., Masutani, C., Hirano, A., Cohn, M.A., Yamaizumi, M., Nakatani, Y., Hanaoka, F.
    • Journal Title

      Genes Cells 11

      Pages: 731-744

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Journal Article] Conserved XPB core structure and motifs for DNA unwinding :implications for pathway selection of transcription or excision repair2006

    • Author(s)
      Fan, L., Anrai, A.S., Cooper, P.K., Iwai, S., Hanaoka.F., and Tainer, J.
    • Journal Title

      Mol.Cell 22(1)

      Pages: 27-37

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209003
  • [Journal Article] Negative regulation of condensin I by CK2 phosphorylation during interphase.2006

    • Author(s)
      A.Takemoto, F.Hanaoka et al.(total 5, last)
    • Journal Title

      EMBO J. 25(22)

      Pages: 5339-5348

    • Data Source
      KAKENHI-PROJECT-16059101
  • [Journal Article] Conserved XPB core structure and motifs for DNA unwinding: implications for pathway selection of transcription or excision repair.2006

    • Author(s)
      Fan, L., Arvai, A.S., Cooper, P.K., Iwai, S., Hanaoka, F., Tainer, J.A.
    • Journal Title

      Mot.Cell 22

      Pages: 27-37

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Journal Article] Negative regulation of condensin I by CK2-mediated phosphorylation.2006

    • Author(s)
      Takemoto, A., Kimura, K., Yanagisawa, J., Yokoyama, S., Hanaoka, F.
    • Journal Title

      EMBO J. 25(22)

      Pages: 5339-5348

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209003
  • [Journal Article] Negative regulation of condensin I by CK2-mediated phosphorylation2006

    • Author(s)
      Takemoto, A., Kimura, K., Yanagisawa, J., Yokoyama, S., and Hanaoka, F.
    • Journal Title

      EMBO J. 25(22)

      Pages: 5339-5348

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209003
  • [Journal Article] Ultraviolet B radiation induces epithelial tumors in mice lacking pol η and mesenchymal tumors in mice deficient for pol2006

    • Author(s)
      Ohkumo, T., Kondo, Y., Yokoi, M., Tsukamoto, T., Yamada, A., Sugimoto, T., Kanao, R., Higashi, Y., Kondoh, H., Tatematsu, M., Masutani, C., Hanaoka, F.
    • Journal Title

      ι.Mal.Cell.Biol. 26

      Pages: 7696-7706

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Journal Article] Deficiency of the Caenorhabditis elegans DNA polymerase eta homologue increases sensitivity to UV radiation during germ-line development.2006

    • Author(s)
      Ohkumo, T., Masutani, C., Eki, T., Hanaoka, F.
    • Journal Title

      Cell Struct.Funct. 31

      Pages: 29-37

    • NAID

      130004137504

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Journal Article] Negative regulation of condensin I by CK2-mediated phosphorylation.2006

    • Author(s)
      Takemoto, A., Kimura, K., Yanagisawa, J., Yokoyama, S., Hanaoka, F.
    • Journal Title

      EMBO J. 25

      Pages: 5339-5348

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Journal Article] Conserved XPB core structure and motifs for DNI unwinding : implications for pathway selection o transcription or excision repair.2006

    • Author(s)
      Fan, L., Arvai, A. S., Cooper, P. K., lwai, S., Hanaoka, F., Tamer, J. A.
    • Journal Title

      Mol. Cell 22(1)

      Pages: 27-37

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209003
  • [Journal Article] Azathioprine and UVA light generate mutagenic oxidative DNA damage.2005

    • Author(s)
      O'Donovan, P., Perrett, C.M., Zhang, X., Montaner, B., Xu, Y.Z., Harwood, C.A., McGregor, J.M., Walker, S.L., Hanaoka, F., Karran, P.
    • Journal Title

      Science 309

      Pages: 1871-1874

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Journal Article] Nucleosomal structure of undamaged DNA regions suppresses the non-specific DNA binding of the XPC complex.2005

    • Author(s)
      Ysuda, T., Sugasawa, K., Shimizu, Y., Iwai, S., Shiomi, T., Hanaoka, F.
    • Journal Title

      DNA Repair 4(3)

      Pages: 389-395

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209003
  • [Journal Article] UV-induced ubiquitylayion of XPC protein mediated by UV-DDB-ubiquitin ligase complex2005

    • Author(s)
      Sugasawa, K., Okuda, Y., Saijo, M., Nishi, R., Matsuda, N., Chu, G., Mori, T., Iwai, S., Tanaka, K., Tanaka, K., and Hanaoka, F.
    • Journal Title

      Cell 121(3)

      Pages: 387-400

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209003
  • [Journal Article] Nucleosomal structure of undamaged DNA regions suppresses the non-specific DNA binding of the XPC complex.2005

    • Author(s)
      Yasuda, T., Sugasawa, K., Shimizu, Y., Iwai, S., Shiomi, T., Hanaoka, F.
    • Journal Title

      DNA Repair 4

      Pages: 389-395

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Journal Article] Alterations of DNA and chromatin structures at telomeres and genetic instability in mouse cells defective in DNA polymerase α.2005

    • Author(s)
      Nakamura, M., Nabetani, A., Mizuno, T., Hanaoka, F., Ishikawa, F.
    • Journal Title

      Mal.Cell.Biol. 25

      Pages: 11073-11088

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Journal Article] Centrin 2 stimulates nucleotide excision repair by interacting with xeroderma pigmentosum group C protein2005

    • Author(s)
      Nishi, R., Okuda, Y., Watanabe, E., Mori, T., Iwai, S., Masutani, C., Sugasawa, K., and Hanaoka, F.
    • Journal Title

      Mol.Cell.Biol. 25(13)

      Pages: 5664-5674

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209003
  • [Journal Article] Crystal structure of SUMO1-conjugated thymine DNA glycosylase.2005

    • Author(s)
      Baba, D., Maita, N., Jee, J.-G., Uchimura, Y., Saitoh, H., Sugasawa, K., Hanaoka, F., Tochio, H., Hiroaki, H., Shirakawa, M.
    • Journal Title

      Nature 435

      Pages: 979-982

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Journal Article] UV-induced ubiquitylation of XPC protein mediated by UV-DDB-ubiquitin ligase complex.2005

    • Author(s)
      K.Sugasawa, F.Hanaoka et al.(total 10, last)
    • Journal Title

      Cell 121(3)

      Pages: 387-400

    • Data Source
      KAKENHI-PROJECT-16059101
  • [Journal Article] Centrin 2 stimulates nucleotide excision repair by interacting with xeroderma pigmentosum group C protein.2005

    • Author(s)
      Nishi, R., Okuda, Y., Watanabe, E., Mori, T., Iwai, S., Masutani, C., Sugasawa, K., Hanaoka, F.
    • Journal Title

      Cell.Biol. 25

      Pages: 5664-5674

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Journal Article] Nucleosomal structure of undamaged DNA regions suppresses the non-specific DNA binding of the XPC complex2005

    • Author(s)
      Ysuda, T., Sugasawa, K., Shimizu, Y., Iwai, S., Shiomi, T., and Hanaoka, F.
    • Journal Title

      DNA Repair 4(3)

      Pages: 389-395

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209003
  • [Journal Article] Different mutation signatures in DNA polymerase η- and MSH6-deficient mice suggest separate roles in antibody diversification.2005

    • Author(s)
      Martomo, S.A., Yang, W.W., Wersto, R.P., Ohkumo, T., Kondo, Y., Yokoi, M., Masutani, C., Hanaoka, F., Gearhart, P.J.
    • Journal Title

      Proc.Natl.Acad Sci.USA 102

      Pages: 8656-8661

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Journal Article] Centrin 2 stimulates nucleotide excision repair by interacting with xeroderma pigmentosum group C protein.2005

    • Author(s)
      Nishi, R., Okuda, Y., Watanabe, E., Mori, T., lwai, S., Masutani, C., Sugasawa, K., Hanaoka, F.
    • Journal Title

      Mol. Cell. Biol. 25(13)

      Pages: 5664-5674

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209003
  • [Journal Article] UV-induced ubiquitylation of XPC protein mediated by UV-DDB-ubiquit in ligase complex.2005

    • Author(s)
      Sugasawa, K., Okuda, Y., Sai jo, M., Nishi, R., Matsuda, N., Chu, G., Mori, T., Iwai, S., Tanaka, K., Tanaka, K., Hanaoka, F.
    • Journal Title

      Cell 121

      Pages: 387-400

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Journal Article] UV-induced ubiquitylation of XPC protein mediated by UV-DDB-ubiquitin ligase complex.2005

    • Author(s)
      Sugasawa, K., Okuda, Y., Saijo, M., Nishi, R., Matsuda, N., Chu, G., Mori, T., lwai, S., Tanaka, K., Tanaka, K., Hanaoka, F.
    • Journal Title

      Cell 121(3)

      Pages: 387-400

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209003
  • [Journal Article] Conformational change in the catalytic site of the ribonuclease YoeB toxin by YefM antitoxin.2005

    • Author(s)
      Kamada, K., Hanaoka, F.
    • Journal Title

      Mal.Cell 19

      Pages: 497-509

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Journal Article] UV-induced ubiquitylation of XPC protein mediated by UV-DDB-ubiquitin ligase complex2005

    • Author(s)
      K. Sugasawa, Y. Okuda, M. Saijo, R. Nishi, N. Matsuda, G. Chu, T. Mori, S. Iwai, K. Tanaka, K. Tanaka, F. Hanaoka
    • Journal Title

      Cell 121

      Pages: 387-400

    • Data Source
      KAKENHI-PROJECT-16059101
  • [Journal Article] Preferential cis-syn thymine dimer bypass by DNA polymerase η occurs with biased fidelity.2004

    • Author(s)
      McCulloch, S.D., Kokoska, R.J., Masutani, C., lwai, S., Hanaoka, F., Kunkel, T.A.
    • Journal Title

      Nature 428

      Pages: 97-100

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12213070
  • [Journal Article] Localization of human Mcm10 is spatially and temporally regulated during S phase.2004

    • Author(s)
      F.Hanaoka.(他2名)
    • Journal Title

      J.Biol.Chem. 279(31)

      Pages: 32569-32577

    • Data Source
      KAKENHI-PROJECT-16059101
  • [Journal Article] DNA binding properties of human DNA polymerase implications for fidelity and polymerase switching of translesion synthesis.2004

    • Author(s)
      Kusumoto, R., Masutani, C., Shimmyo, S., lwai, S., Hanaoka, F.
    • Journal Title

      Genes Cells 9

      Pages: 1139-1150

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12213070
  • [Journal Article] Relative levels of the two mammalian Rad23 homologs determine composition and stability of th exeroderma pigmentosum group C protein complex2004

    • Author(s)
      Okuda, Y., Nishi, R., Ng, J.M.Y., Vermeulen, W., van der Horst, G.T.J., Mori, T., Hoeijmakers, J.H.J., Hanaoka, F., and Sugasawa, K.
    • Journal Title

      DNA Repair 3(10)

      Pages: 1285-1295

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209003
  • [Journal Article] Relative levels of the two mammalian Rad23 homologs determine composition and stability of the xeroderma pigmentosum group C protein complex.2004

    • Author(s)
      Okuda, Y., Nishi, R., Ng, J. M. Y., Vermeulen, W., van der Horst, G. T. J., Mori, T., Hoeijmakers, J. H. J., Hanaoka, E. Sugasawa, K.
    • Journal Title

      DNA Repair 3(10)

      Pages: 1285-1295

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209003
  • [Journal Article] DNA binding properties of human DNA polymerase η: implications for fidelity and polymerase switching of translesion synthesis.2004

    • Author(s)
      F.Hanaoka.(他4名)
    • Journal Title

      Genes Cells 9(12)

      Pages: 1139-1150

    • Data Source
      KAKENHI-PROJECT-16059101
  • [Journal Article] Translesion synthesis by human DNA polymerase η across thymine glycol lesions.2002

    • Author(s)
      Kusumoto, R., Masutani, C., lwai, S., Hanaoka, F.
    • Journal Title

      Biochemistry 41

      Pages: 6090-6099

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12213070
  • [Journal Article] Mechanisms of accurate translesion synthesis by human DNA polymerase-η.2000

    • Author(s)
      Masutani, C., Kusumoto, R., lwai, S., Hanaoka, F.
    • Journal Title

      EMBO J. 19

      Pages: 3100-3109

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12213070
  • [Journal Article] Low fidelity DNA synthesis by human DNA polymerase η.2000

    • Author(s)
      Matsuda, T., Bebenek, K., Masutani, C., Hanaoka, F., Kunkel, T.A.
    • Journal Title

      Nature 404

      Pages: 1011-1013

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12213070
  • [Journal Article] Aberrant DNA polymerase alpha is excluded from the nucleus by defective import and degradation in the nucleus.

    • Author(s)
      Eichinger, C.S., Mizuno, T., Mizuno, K., Miyake, Y., Yanagi, K., Imamoto, N., Hanaoka, F.
    • Journal Title

      J. Biol. Chem 284

      Pages: 30604-30614

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Journal Article] UV-induced ubiquitylation of XPC protein mediated by UV-DDB-ubiquitin ligase complex.

    • Author(s)
      Kaoru Sugasawa., Yuki Okuda., Masafumi Saijo., Ryotaro Nishi., Noriyuki Matsuda., Gilbert Chu., Toshio Mori., Shigenori Iwai., Keiji Tanaka., Kiyoji Tanaka, Fumio Hanaoka.
    • Journal Title

      Cell (in press.)

    • Data Source
      KAKENHI-PROJECT-12143101
  • [Journal Article] Different mutation signatures in DNA polymerase η-and MSH6-deficient mice suggest separate roles in antibody diversification.

    • Author(s)
      Martomo, S.A., Yang, W.W., Wersto, R.P., Ohkumo, T., Kondo, Y., Yokoi, M., Masutani, C., Hanaoka, F., Gearhart, P.J.
    • Journal Title

      Proc.Natl.Acad.Sci.USA (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12213070
  • [Patent] DNA損傷修復剤とスクリーニング方法2009

    • Inventor(s)
      菅澤薫、花岡文雄、清水祐一郎
    • Industrial Property Rights Holder
      科学技術振興機構、(独)理化学研究所
    • Acquisition Date
      2009-11-06
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Patent] 新規ヒトトポイソメラーゼ2α阻害蛋白質及びその利用2005

    • Inventor(s)
      中西啓、花岡文雄、大海忍
    • Industrial Property Rights Holder
      (独)理化学研究所
    • Acquisition Date
      2005-04-08
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Presentation] アクリルアミドの活性代謝物であるグリシルアミドのデオキシグアノシンN7位付加体はDNA複製阻害と点突然変異を誘発する2019

    • Author(s)
      赤木純一, 横井雅幸, Young-Man Cho, 岩井成憲, 花岡文雄, 菅澤 薫, 小川久美子
    • Organizer
      日本薬学会第140年会
    • Data Source
      KAKENHI-PROJECT-17K00551
  • [Presentation] DNAポリメラーゼ・イータと脱ユビキチン化酵素の相互作用の解析2019

    • Author(s)
      案済 萌, 西村 潤, 菅野新一郎, 安井 明, 酒井 恒, 菅澤 薫, 花岡文雄, 横井雅幸
    • Organizer
      第42回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-17K00551
  • [Presentation] C57BL/6J野生型およびPolκ欠損マウスにおけるベンゾ[a]ピレンおよびα‐ナフトフラボン併用投与の効果2019

    • Author(s)
      赤木純一, CHO Young‐Man, 豊田武士, 横井雅幸, 花岡文雄, 大森治夫, 小川久美子
    • Organizer
      第35回日本毒性病理学会学術総会
    • Data Source
      KAKENHI-PROJECT-15H04646
  • [Presentation] TLSポリメラーゼの損傷部位への導入過程を生細胞イメージングにより解析する試み2019

    • Author(s)
      福永 匠, 尾崎未羽, 佐藤正康, 酒井 恒, 菅澤 薫, 花岡文雄, 横井雅幸
    • Organizer
      第42回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-17K00551
  • [Presentation] N7-グリシドアミドdG付加体により誘発されるDNA複製阻害と変異原性の解析2019

    • Author(s)
      赤木純一, 横井雅幸, Young-Man Cho, 岩井成憲, 花岡文雄, 菅澤 薫, 小川久美子
    • Organizer
      第42回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-17K00551
  • [Presentation] Analysis of interaction between DNA polymerase η and deubiquitinating enzyme2018

    • Author(s)
      案済萌、西村潤、菅野新一郎、安井明、菅澤薫、花岡文雄、横井雅幸
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-17K00551
  • [Presentation] Effect of Polκ deficiency on benzo[a]pyrene-induced tumorigenesis2018

    • Author(s)
      Akagi, J., Cho, Y-M., Toyoda, T., Yokoi, M., Hanaoka, F., Ohmori, H., Ogawa, K.
    • Organizer
      The 5th DNA polymerase meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K00551
  • [Presentation] Benzo[a]pyrene-induced tumorigenesis in Polκ-knockout mice2018

    • Author(s)
      Akagi, J., Cho, Y-M., Toyoda, T., Yokoi, M., Hanaoka, F., Ohmori, H., Ogawa, K.
    • Organizer
      The 11th 3R+3C Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K00551
  • [Presentation] N7-glycidamide-dG adduct inhibits DNA replication in mammalian cells2018

    • Author(s)
      Akagi, J., Yokoi, M., Cho, Y-M., Yamamoto, J., Mizuta, Y., Iwai, S., Hanaoka, F., Ogawa, K.
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-17K00551
  • [Presentation] ベンゾ[a]ピレン誘発発がんに対するPolκの寄与の解析2018

    • Author(s)
      赤木純一, Young-Man Cho, 豊田武士, 水田保子, 横井雅幸, 大森治夫, 花岡文雄, 小川久美子
    • Organizer
      日本薬学会第138年会
    • Data Source
      KAKENHI-PROJECT-15H04646
  • [Presentation] Benzo[a]pyrene-induced tumorigenesis in Polκ-knockout mice2018

    • Author(s)
      Jun-ichi Akagi, Young-Man Cho, Takeshi Toyoda, Masayuki Yokoi, Fumio Hanaoka, Haruo Ohmori, Kumiko Ogawa
    • Organizer
      The 11th 3R & 3C Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04646
  • [Presentation] N7グリシドアミドdG付加体は哺乳類細胞においてDNA複製を阻害する2018

    • Author(s)
      赤木純一, 横井雅幸, Young-Man Cho, 岩井成憲, 花岡文雄, 小川久美子
    • Organizer
      第41回日本分子生物学会年会(2018年11月28日、横浜)
    • Data Source
      KAKENHI-PROJECT-15H04646
  • [Presentation] Translesion synthesis-associated chromatin remodeling factors contribute the function of human DNA polymerase η in cisplatin-treated cells2018

    • Author(s)
      Yokoi, M., Shikaya, Y., Sugasawa, K., Hanaoka, F.
    • Organizer
      The 11th 3R+3C Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K00551
  • [Presentation] Analysis of contribution of Polκ to benzo[a]pyrene-induced tumorigenesis2018

    • Author(s)
      Akagi, J., Cho, Y-M., Toyoda, T., Mizuta, Y., Yokoi, M., Hanaoka, F., Ohmori, H., Ogawa, K.
    • Organizer
      日本薬学会第138年会
    • Data Source
      KAKENHI-PROJECT-17K00551
  • [Presentation] Effect of Polκ deficiency on benzo[a]pyrene-induced tumorigenesis2018

    • Author(s)
      Jun-ichi Akagi, Young-Man Cho, Takeshi Toyoda, Masayuki Yokoi, Fumio Hanaoka, Haruo Ohmori, Kumiko Ogawa
    • Organizer
      5th DNA Polymerases meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04646
  • [Presentation] シスプラチン処理した細胞においてヒトDNAポリメラーゼηの働きに寄与するクロマチン構造変換因子2017

    • Author(s)
      横井雅幸、菅澤薫、花岡文雄
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-15H04646
  • [Presentation] 損傷乗り越え型DNAポリメラーゼ イータ・イオタ・カッパ三重欠損細胞を用いた新規遺伝毒性試験法の研究2017

    • Author(s)
      赤木純一, 横井雅幸, Young-Man Cho, 豊田武士, 大森治夫, 花岡文雄, 小川久美子
    • Organizer
      第3回次世代を担う若手のためのレギュラトリーサイエンスフォーラム
    • Data Source
      KAKENHI-PROJECT-15H04646
  • [Presentation] TLS polymerases and mutagenesis2017

    • Author(s)
      Fumio Hanaoka
    • Organizer
      ICEM-ACEM 2017 Satellite Symposium on DNA Repair
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04646
  • [Presentation] TLS polymerases and mutagenesis2017

    • Author(s)
      Hanaoka F
    • Organizer
      ICEM-ACEM 2017 Satellite Synposium on DNA Repair
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K14953
  • [Presentation] My CV: From our studies on XP-C to XP-V. 6th US-Japan DNA Repair Meeting2017

    • Author(s)
      Fumio Hanaoka
    • Organizer
      6th US-Japan DNA Repair Meeting
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04646
  • [Presentation] Contribution of Polκ to tumorigenesis in the forestomach of benzo[a]pyrene-fed mice2017

    • Author(s)
      Akagi, J., Cho, Y-M., Toyoda, T., Mizuta, Y., Yokoi, M., Hanaoka, F., Ohmori, H., Ogawa, K.
    • Organizer
      ComBio2017
    • Data Source
      KAKENHI-PROJECT-17K00551
  • [Presentation] ヒトMCM10のMCM2-7相互作用ドメインの同定2017

    • Author(s)
      泉雅子、水野武、柳憲一郎、杉村和人、奥村克純、今本尚子、阿部知子、花岡文雄
    • Organizer
      第24回DNA複製・組換え・修復ワークショップ
    • Data Source
      KAKENHI-PROJECT-15K14953
  • [Presentation] My CV: From our studies on XP-C to XP-V2017

    • Author(s)
      Hanaoka F
    • Organizer
      6th US-Japan DNA Repair Meeting
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K14953
  • [Presentation] シスプラチン誘発DNA鎖内架橋の乗り越え合成に関わるヒストン修飾酵素とクロマチン構造変換因子の探索2017

    • Author(s)
      横井雅幸、鹿谷有由希、菅澤薫、花岡文雄
    • Organizer
      第24回DNA複製・組換え・修復ワークショップ
    • Data Source
      KAKENHI-PROJECT-15K14953
  • [Presentation] ベンゾ[a]ピレン混餌投与によるマウス前胃腫瘍発生に対するPolκの寄与2017

    • Author(s)
      Jun-ichi Akagi, Young-Man Cho, Takeshi Toyoda, Yasuko Mizuta, Masayuki Yokoi, Fumio Hanaoka, Haruo Ohmori, Kumiko Ogawa
    • Organizer
      2017年度生命科学系学会合同年次大会
    • Data Source
      KAKENHI-PROJECT-15H04646
  • [Presentation] シスプラチン誘発DNA鎖内架橋の乗り越え合成に関わるヒストン修飾酵素とクロマチン構造変換因子の探索2017

    • Author(s)
      横井雅幸、鹿谷有由希、菅澤薫、花岡文雄
    • Organizer
      第24回DNA複製・組換え・修復ワークショップ
    • Data Source
      KAKENHI-PROJECT-15H04646
  • [Presentation] ヒトMCM10のMCM2-7相互作用ドメインの同定2017

    • Author(s)
      泉雅子、水野武、柳憲一郎、杉村和人、奥村克純、今本尚子、阿部知子、花岡文雄
    • Organizer
      第24回DNA複製・組換え・修復ワークショップ
    • Data Source
      KAKENHI-PROJECT-15H04646
  • [Presentation] シスプラチン処理した細胞においてヒトDNAポリメラーゼηの働きに寄与するクロマチン構造変換因子2017

    • Author(s)
      横井雅幸、菅澤薫、花岡文雄
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-15K14953
  • [Presentation] Mutant analyses of human DNA polymerase eta based on high-resolution crystal structures of the protein-DNA-dNTP complex.2016

    • Author(s)
      Hanaoka F, Yokoi M, Masutani C, Yang W
    • Organizer
      4th International Meeting on DNA Polymerases.
    • Place of Presentation
      Biarritz, France
    • Year and Date
      2016-10-04
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04646
  • [Presentation] Mutant analyses of human DNA polymerase eta based on high-resolution crystal structures of the protein-DNA-dNTP complex.2016

    • Author(s)
      Hanaoka F, Yokoi M, Masutani C, Yang W
    • Organizer
      4th International Meeting on DNA Polymerases
    • Place of Presentation
      Biarritz, France
    • Year and Date
      2016-10-04
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K14953
  • [Presentation] Pol eta, Pol iota, and Pol kappa exhibit different genetic interactions to various compounds of different genotoxic mechanisms and the triple knockout cells are useful for screening of genotoxins.2016

    • Author(s)
      Akagi J, Yokoi M, Toyoda T, Cho YM, Ohmori H, Hanaoka F, Ogawa K
    • Organizer
      Gordon Research Conference on Mutagenesis
    • Place of Presentation
      Girona, Spain
    • Year and Date
      2016-06-05
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04646
  • [Presentation] Cancer and translesion synthesis polymerases.2016

    • Author(s)
      Sakurai Y, Yokoi M, Hanaoka F
    • Organizer
      2016 Cold Spring Harbor Asia Conference-DNA Metabolism, Genomic Stability and Diseases
    • Place of Presentation
      Suzhou, China
    • Year and Date
      2016-06-13
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04646
  • [Presentation] Cancer and translesion synthesis polymerases.2016

    • Author(s)
      Sakurai Y, Yokoi M, Hanaoka F
    • Organizer
      2016 Cold Spring Harbor Asia Conference-DNA Metabolism,Genomic Stability and Diseases
    • Place of Presentation
      Suzhou, China
    • Year and Date
      2016-06-13
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K14953
  • [Presentation] 総括2015

    • Author(s)
      花岡文雄
    • Organizer
      BMB2015 ワークショップ「放射線生物影響の課題に挑む分子生物学研究の力」
    • Place of Presentation
      神戸
    • Year and Date
      2015-12-01
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K14953
  • [Presentation] 総括2015

    • Author(s)
      花岡文雄
    • Organizer
      BMB2015 ワークショップ「放射線生物影響の課題に挑む分子生物学研究の力」
    • Place of Presentation
      神戸
    • Year and Date
      2015-12-01
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-22131001
  • [Presentation] 私のDNA修復研究: XPCからXPVへ2015

    • Author(s)
      花岡文雄
    • Organizer
      新学術領域研究「ゲノム普遍的制御」(H22~H26年度)公開シンポジウム『ゲノム安定性の機構と生命の維持ー進化、癌化、老化の理解のために』
    • Place of Presentation
      京都大学
    • Year and Date
      2015-08-28
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04646
  • [Presentation] Structural and biochemical analyses for accommodation and recognition of UV-damaged bases within nucleosome.2015

    • Author(s)
      Osakabe A, Tachiwana H, Kagawa W, Horikoshi N, Matsumoto S, Yamamoto J, Hanaoka F, Sugasawa K, Iwai S, Kurumizaka H
    • Organizer
      「クロマチン動構造」国際シンポジウム
    • Place of Presentation
      淡路島、兵庫
    • Year and Date
      2015-08-23
    • Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-22131001
  • [Presentation] Regulation of the protein level of Rev1 in fission yeast.2015

    • Author(s)
      Uchiyama M, TerunumaJ, Hanaoka F
    • Organizer
      Zing Genomic Integrity Conference 2015
    • Place of Presentation
      Cairns, Australia
    • Year and Date
      2015-08-01
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04646
  • [Presentation] 私のDNA修復研究:XPCからXPVへ2015

    • Author(s)
      花岡文雄
    • Organizer
      新学術領域研究「ゲノム普遍的制御」終了シンポジウム:ゲノム安定性の機構と生命の維持 -進化、癌化、老化の理解のために
    • Place of Presentation
      京都
    • Year and Date
      2015-08-29
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-22131001
  • [Presentation] Forty years of DNA damage tolerance.2015

    • Author(s)
      Hanaoka F
    • Organizer
      15th International Congress of Radiation Research (ICRR 2015)
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2015-05-25
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K14953
  • [Presentation] Regulation of the protein level of Rev1 in fission yeast.2015

    • Author(s)
      Uchiyama M, Terunuma J, Hanaoka F
    • Organizer
      Genomic Integrity, ZING Conference 2015
    • Place of Presentation
      Cairns, Australia
    • Year and Date
      2015-08-01
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-22131001
  • [Presentation] Forty years of DNA damage tolerance.2015

    • Author(s)
      Hanaoka F
    • Organizer
      15th International Congress of Radiation Research (ICRR 2015)
    • Place of Presentation
      京都国際会館
    • Year and Date
      2015-05-25
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04646
  • [Presentation] Regulation of the protein level of Rev1 in fission yeast.2015

    • Author(s)
      Uchiyama M, Terunuma J, Hanaoka F
    • Organizer
      Genomic Integrity, ZING Conference 2015
    • Place of Presentation
      Cairns, Australia
    • Year and Date
      2015-08-01
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K14953
  • [Presentation] Structural and biochemical analyses for accommodation and recognition of UV-damaged bases within nucleosome.2015

    • Author(s)
      Osakabe A, Tachiwana H, Kagawa W, Horikoshi N, Matsumoto S, Yamamoto J, Hanaoka F, Sugasawa K, Iwai S, Kurumizaka H
    • Organizer
      「クロマチン動構造」国際シンポジウム
    • Place of Presentation
      淡路島、兵庫
    • Year and Date
      2015-08-23
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K14953
  • [Presentation] 私のDNA修復研究:XPCからXPVへ.2015

    • Author(s)
      花岡文雄
    • Organizer
      新学術領域研究「ゲノム普遍的制御」終了シンポジウム:ゲノム安定性の機構と生命の維持 -進化、癌化、老化の理解のために
    • Place of Presentation
      京都
    • Year and Date
      2015-08-29
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K14953
  • [Presentation] Forty years of DNA damage tolerance.2015

    • Author(s)
      Hanaoka F
    • Organizer
      15th International Congress of Radiation Research (ICRR 2015)
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2015-05-25
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-22131001
  • [Presentation] 損傷トレランスと突然変異生成に働く乗り越え複製ポリメラーゼ2014

    • Author(s)
      花岡文雄
    • Organizer
      日本薬学会第134年会特別講演
    • Place of Presentation
      熊本
    • Invited
    • Data Source
      KAKENHI-PROJECT-22249005
  • [Presentation] Defective translesion DNA synthesis and links to human disease2014

    • Author(s)
      Hanaoka, F
    • Organizer
      International Symposium on Xeroderma Pigmentosum and Related Diseases : Disorders of DNA Damage Response–Bench to Bedside-
    • Place of Presentation
      神戸
    • Invited
    • Data Source
      KAKENHI-PROJECT-22249005
  • [Presentation] All road leads to DNA-lesion bypass : mechanisms of translesion synthesis2014

    • Author(s)
      Yang, W., Lee, Young-Sam, Zhao, Y., Nakamura, T., Biertümpfel, C., Yamagata, Y., Hua, Y., and Hanaoka, F
    • Organizer
      International Conference, Kyoto, 2014: Replication, Repair and Recombination; coupling mechanisms and chromatin dynamics for genome integrity
    • Place of Presentation
      京都
    • Invited
    • Data Source
      KAKENHI-PROJECT-22249005
  • [Presentation] Regulation of DNA damage tolerance distinct from Polη-mediated translesion synthesis2014

    • Author(s)
      Kanao, R., Masuda, Y., Hanaoka, F., and Masutani, C
    • Organizer
      International Conference, Kyoto, 2014: Replication, Repair and Recombination; coupling mechanisms and chromatin dynamics for genome integrity
    • Place of Presentation
      京都
    • Invited
    • Data Source
      KAKENHI-PROJECT-22249005
  • [Presentation]2014

    • Author(s)
      Osakabe, A., Tachiwana, H., Horikoshi, N., Kagawa, W., Yasuda, T., Hanaoka, F., Sugasawa, K., Iwai, S., and Kurumizaka, H
    • Organizer
      International Conference, Kyoto, 2014: Replication, Repair and Recombination; coupling mechanisms and chromatin dynamics for genome integrity
    • Place of Presentation
      京都
    • Invited
    • Data Source
      KAKENHI-PROJECT-22249005
  • [Presentation] Physiological role of TLS polymerases in mouse skin upon UV irradiation2014

    • Author(s)
      Yokoi, M., Sakurai, Y., Hando, N., Morita, D., and Hanaoka, F
    • Organizer
      International Conference, Kyoto, 2014: Replication, Repair and Recombination; coupling mechanisms and chromatin dynamics for genome integrity
    • Place of Presentation
      京都
    • Invited
    • Data Source
      KAKENHI-PROJECT-22249005
  • [Presentation] Structure and function of mammalian DNA polymerase eta with special reference on translesion synthesis and somatic hypermutation.2013

    • Author(s)
      Hanaoka F
    • Organizer
      Seminar at Graduate School of Medicine, Kyoto University
    • Place of Presentation
      京都大学医学部
    • Year and Date
      2013-05-27
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-22131001
  • [Presentation] がんとは何か?ーその発生のメカニズムを探るー2013

    • Author(s)
      花岡文雄
    • Organizer
      読売サイエンスフォーラム
    • Place of Presentation
      学習院大学
    • Year and Date
      2013-07-27
    • Invited
    • Data Source
      KAKENHI-PLANNED-22131008
  • [Presentation] Structure and function of mammalian DNA polymerase eta with special reference on translesion synthesis and somatic hypermutation2013

    • Author(s)
      Hanaoka, F
    • Organizer
      京都大学大学院医学研究科・免疫ゲノム医学特別セミナー
    • Place of Presentation
      京都
    • Year and Date
      2013-05-27
    • Invited
    • Data Source
      KAKENHI-PROJECT-22249005
  • [Presentation] DNAポリメラーゼ・イータ—その構造と多彩な機能—2013

    • Author(s)
      花岡文雄
    • Organizer
      公開シンポジウム「遺伝情報場:構築を担う分子のダイナミクスと制御」
    • Place of Presentation
      東京
    • Year and Date
      2013-01-11
    • Invited
    • Data Source
      KAKENHI-PROJECT-22249005
  • [Presentation] がんとは何か?ーその発生のメカニズムを探るー2013

    • Author(s)
      花岡文雄
    • Organizer
      読売サイエンスフォーラム
    • Place of Presentation
      学習院大学
    • Year and Date
      2013-07-27
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-22131001
  • [Presentation] Role of DNA polymerase eta in somatic hypermutation2013

    • Author(s)
      Hanaoka, F
    • Organizer
      The 3^<rd> Frence-Japanese Cancer Meeting
    • Place of Presentation
      Toulouse, France
    • Invited
    • Data Source
      KAKENHI-PROJECT-22249005
  • [Presentation] Structure and function of mammalian DNA polymerase eta with special reference on translesion synthesis and somatic hypermutation.2013

    • Author(s)
      Hanaoka F
    • Organizer
      Seminar at Graduate School of Medicine, Kyoto University
    • Place of Presentation
      京都大学医学部
    • Year and Date
      2013-05-27
    • Invited
    • Data Source
      KAKENHI-PLANNED-22131008
  • [Presentation] Functional roles of mammalian DNA polymerase eta, the product of the XP-V responsible gene.2012

    • Author(s)
      Hanaoka F
    • Organizer
      The 3rd Erling Seeberg Symposium on DNA Repair
    • Place of Presentation
      Trondheim and Orland, Norway
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-22131001
  • [Presentation] Alternative translesion synthesis pathway via interaction between stalled DNA polymerase eta and REV12012

    • Author(s)
      Hanaoka F
    • Organizer
      The 8th 3R Symposium together with National Institute of Genetics “2012 International Symposium”: “Molecular Mechanisms and Pathology of the 3R”
    • Place of Presentation
      淡路市、兵庫
    • Invited
    • Data Source
      KAKENHI-PROJECT-22249005
  • [Presentation] Functional roles of mammalian DNA polymerase eta, the product of the XP-V responsible gene.2012

    • Author(s)
      Hanaoka F
    • Organizer
      The 3rd Erling Seeberg Symposium on DNA Repair
    • Place of Presentation
      Trondheim and Orland, Norway
    • Invited
    • Data Source
      KAKENHI-PLANNED-22131008
  • [Presentation] Involvement of DNA polymerase eta-REV1 interaction in a part of error-prone translesion DNA synthesis.2012

    • Author(s)
      Hanaoka F
    • Organizer
      The 4th U.S.-Japan DNA Repair Meeting
    • Place of Presentation
      Virginia, USA
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-22131001
  • [Presentation] Functional roles of mammalian DNA polymeraseη, the product of the XP-V responsible gene2012

    • Author(s)
      Hanaoka, F., Yokoi, M
    • Organizer
      3rd Erling Seeberg Symposium
    • Place of Presentation
      Trondheim and Orland, Norway
    • Invited
    • Data Source
      KAKENHI-PROJECT-22249005
  • [Presentation] Functional roles of mammalian DNA polymerase eta2012

    • Author(s)
      Hanaoka, F
    • Organizer
      Second Japanese-French Cancer Workshop
    • Place of Presentation
      鳴門
    • Invited
    • Data Source
      KAKENHI-PROJECT-22249005
  • [Presentation] Functional roles of mammalian DNA polymerase eta2012

    • Author(s)
      Hanaoka F
    • Organizer
      2nd Japanese-Frence Cancer Workshop
    • Place of Presentation
      鳴門市、徳島
    • Invited
    • Data Source
      KAKENHI-PLANNED-22131008
  • [Presentation] Functional roles of mammalian DNA polymerase eta, the product of the XP-V responsible gene.2012

    • Author(s)
      Hanaoka F
    • Organizer
      The 3rd Erling Seeberg Symposium on DNA Repair
    • Place of Presentation
      Trondheim and Orland, Norway
    • Invited
    • Data Source
      KAKENHI-PROJECT-22249005
  • [Presentation] Involvement of DNA polymerase eta-REV1 interaction in a part of error-prone translesion DNA synthesis.2012

    • Author(s)
      Hanaoka F
    • Organizer
      The 4th U.S.-Japan DNA Repair Meeting
    • Place of Presentation
      Virginia, USA
    • Invited
    • Data Source
      KAKENHI-PLANNED-22131008
  • [Presentation] Functional roles of mammalian DNA polymerase eta2012

    • Author(s)
      Hanaoka F
    • Organizer
      2nd Japanese-Frence Cancer Workshop
    • Place of Presentation
      鳴門市、徳島
    • Invited
    • Data Source
      KAKENHI-PROJECT-22249005
  • [Presentation] 突然変異、損傷乗り越え複製2012

    • Author(s)
      花岡文雄.能美先生
    • Organizer
      能美健彦先生ご退官記念祝賀会
    • Place of Presentation
      東京
    • Year and Date
      2012-07-07
    • Invited
    • Data Source
      KAKENHI-PROJECT-22249005
  • [Presentation] Alternative translesion synthesis pathway via interaction between stalled DNA polymerase eta and REV12012

    • Author(s)
      Hanaoka F
    • Organizer
      The 8th 3R Symposium together with National Institute of Genetics “2012 International Symposium”: “Molecular Mechanisms and Pathology of the 3R”
    • Place of Presentation
      淡路市、兵庫
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-22131001
  • [Presentation] Structure, mechanism and functions of mammalian DNA polymerase eta2012

    • Author(s)
      Hanaoka, F
    • Organizer
      Special Seminar at the University of Texas MD Anderson Cancer Center
    • Place of Presentation
      Austin, USA
    • Year and Date
      2012-04-10
    • Invited
    • Data Source
      KAKENHI-PROJECT-22249005
  • [Presentation] Alternative translesion synthesis pathway via interaction between stalled DNA polymeraseηand REV12012

    • Author(s)
      Hanaoka, F., Yokoi, M
    • Organizer
      8th 3R Symposium
    • Place of Presentation
      淡路島
    • Invited
    • Data Source
      KAKENHI-PROJECT-22249005
  • [Presentation] Physiological role of DNA polymeraseη-REV1 interaction in mammalian cells2012

    • Author(s)
      Yokoi, M., Hanaoka, F
    • Organizer
      Cantoblanco Workshops : Polymerases Involved in DNA Replication, Repair and Mutagenesis
    • Place of Presentation
      Madrid, Spain
    • Invited
    • Data Source
      KAKENHI-PROJECT-22249005
  • [Presentation] Functional roles of mammalian DNA polymerase eta2012

    • Author(s)
      Hanaoka F
    • Organizer
      2nd Japanese-Frence Cancer Workshop
    • Place of Presentation
      鳴門市、徳島
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-22131001
  • [Presentation] Involvement of DNA polymerase eta-REV1 interaction in a part of error-prone translesion DNA synthesis.2012

    • Author(s)
      Hanaoka F
    • Organizer
      The 4th U.S.-Japan DNA Repair Meeting
    • Place of Presentation
      Virginia, USA
    • Invited
    • Data Source
      KAKENHI-PROJECT-22249005
  • [Presentation] Alternative translesion synthesis pathway via interaction between stalled DNA polymerase eta and REV12012

    • Author(s)
      Hanaoka F
    • Organizer
      The 8th 3R Symposium together with National Institute of Genetics “2012 International Symposium”: “Molecular Mechanisms and Pathology of the 3R”
    • Place of Presentation
      淡路市、兵庫
    • Invited
    • Data Source
      KAKENHI-PLANNED-22131008
  • [Presentation] Involvement of DNA polymeraseη-REV1 interaction in a part of error-prone translesion DNA synthesis2012

    • Author(s)
      Hanaoka, F., Yokoi, M
    • Organizer
      US-Japan DNA Repair Workshop
    • Place of Presentation
      Leesburg, USA
    • Invited
    • Data Source
      KAKENHI-PROJECT-22249005
  • [Presentation] DNA修復と疾患:色素性乾皮症を中心に2011

    • Author(s)
      花岡文雄
    • Organizer
      第28回日本医学会総会
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PLANNED-22131008
  • [Presentation] DNA修復と疾患:色素性乾皮症を中心に2011

    • Author(s)
      花岡文雄
    • Organizer
      第28回日本医学会総会
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-22249005
  • [Presentation] Biochemical properties and structure of human DNA polymerase &eta, xeroderma pigmentosum variant-responsible gene product2011

    • Author(s)
      Hanaoka, F.
    • Organizer
      GDRI France Japan Conference
    • Place of Presentation
      Montpellier, France
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-22131001
  • [Presentation] Biochemical properties and structure of human DNA polymerase &eta, xeroderma pigmentosum variant-responsible gene product2011

    • Author(s)
      Hanaoka, F.
    • Organizer
      GDRI France Japan Conference
    • Place of Presentation
      Montpellier, France
    • Invited
    • Data Source
      KAKENHI-PLANNED-22131008
  • [Presentation] DNA修復研究における生化学的アプローチ2011

    • Author(s)
      花岡文雄
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都
    • Invited
    • Data Source
      KAKENHI-PROJECT-22249005
  • [Presentation] DNA修復と疾患:色素性乾皮症を中心に2011

    • Author(s)
      花岡文雄
    • Organizer
      第28回日本医学会総会
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-22249005
  • [Presentation] Biochemical properties and structure of human DNA polymerase η.2011

    • Author(s)
      Hanaoka, F.
    • Organizer
      6th UK-Japan Cell Cycle Workshop
    • Place of Presentation
      Lake Windermere, UK
    • Invited
    • Data Source
      KAKENHI-PROJECT-22249005
  • [Presentation] Biochemical properties and structure of human DNA polymerase &eta, xeroderma pigmentosum variant-responsible gene product2011

    • Author(s)
      Hanaoka, F.
    • Organizer
      GDRI France Japan Conference
    • Place of Presentation
      Montpellier, France
    • Invited
    • Data Source
      KAKENHI-PROJECT-22249005
  • [Presentation] DNA修復研究における生化学的アプローチ2011

    • Author(s)
      花岡文雄
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      国立京都国際会議場
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-22131001
  • [Presentation] Biochemical properties and structure of human DNA polymerase η.2011

    • Author(s)
      Hanaoka, F.
    • Organizer
      6th UK-Japan Cell Cycle Workshop
    • Place of Presentation
      Lake Windermere, UK
    • Invited
    • Data Source
      KAKENHI-PLANNED-22131008
  • [Presentation] DNA修復と疾患:色素性乾皮症を中心に2011

    • Author(s)
      花岡文雄
    • Organizer
      第28回日本医学会総会
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-22131001
  • [Presentation] Biochemical properties and structure of human DNA polymerase &eta, xeroderma pigmentosum variant- responsible gene product2011

    • Author(s)
      Hanaoka, F., Kondo, Y., Masutani, C., Biertümpfel, C., Zhao, Y., Yang, W
    • Organizer
      GDRI France Japan Conference
    • Place of Presentation
      Montpellier, France
    • Invited
    • Data Source
      KAKENHI-PROJECT-22249005
  • [Presentation] Biochemical properties and structure of human DNA polymerase η.2011

    • Author(s)
      Hanaoka, F.
    • Organizer
      6th UK-Japan Cell Cycle Workshop
    • Place of Presentation
      Lake Windermere, UK
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-22131001
  • [Presentation] DNA修復研究における生化学的アプローチ2011

    • Author(s)
      花岡文雄
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      国立京都国際会議場
    • Invited
    • Data Source
      KAKENHI-PROJECT-22249005
  • [Presentation] DNA修復研究における生化学的アプローチ2011

    • Author(s)
      花岡文雄
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      国立京都国際会議場
    • Invited
    • Data Source
      KAKENHI-PLANNED-22131008
  • [Presentation] Tumorigenesis induced by chronic treatment with UV-B in Pol eta- and Xpc-deficient mice2010

    • Author(s)
      Hanaoka, F
    • Organizer
      Gordon Research Conference on Mutagenesis
    • Place of Presentation
      Waterville, Maine, USA
    • Invited
    • Data Source
      KAKENHI-PROJECT-22249005
  • [Presentation] Regulation of translesion DNA synthesis with special emphasis on DNA polymerase η and PCNA ubiquitylation.2010

    • Author(s)
      Hanaoka, F., Deguchi, S., Kanao, R., Masutani, C.
    • Organizer
      EMBO Workshop, The Interface between the Ubiquitin Family and the DNA Damage Response
    • Place of Presentation
      Rovinj, Croatia
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Presentation] Tumorigenesis induced by chronic treatment with UV-B in Pol eta- and X-pc-deficient mice2010

    • Author(s)
      花岡文雄
    • Organizer
      Gordon Research Conference on Mutagenesis
    • Place of Presentation
      Waterville, Maine, USA(招待講演)
    • Year and Date
      2010-08-05
    • Data Source
      KAKENHI-ORGANIZER-22131001
  • [Presentation] Tumorigenesis induced by chronic treatment with UV-B in Pol η- and Xpc-deficient mice.2010

    • Author(s)
      Hanaoka, F.
    • Organizer
      Gordon Research Conference, Mutagenesis
    • Place of Presentation
      Waterville, USA
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Presentation] Regulation of translesion DNA synthesis with special emphasis on DNA polymerase eta and PCNA ubiquitylation2010

    • Author(s)
      Hanaoka, F., Deguchi, S., Kanao, R., and Masutani, C
    • Organizer
      The EMBO Workshop on"Interface between the Ubiquitin Family and the DNA Damage Response"
    • Place of Presentation
      Rovinj, Croatia
    • Invited
    • Data Source
      KAKENHI-PROJECT-22249005
  • [Presentation] 遺伝子の傷を治して発がんを抑える2010

    • Author(s)
      花岡文雄
    • Organizer
      大切な「いのち」を守る科学学際生命科学東京コンソーシアム市民講演会平成21年度文部科学省・戦略的大学連携支援プログラム採択
    • Place of Presentation
      東京
    • Year and Date
      2010-04-10
    • Invited
    • Data Source
      KAKENHI-PROJECT-22249005
  • [Presentation] Regulation of translesion DNA synthesis with special emphasis on DNA polymerase eta and PCNA ubiquitylation2010

    • Author(s)
      花岡文雄
    • Organizer
      EMBOワークショップ「ユビキチンファミリーとDNA損傷応答の関わり」
    • Place of Presentation
      ロビーニ、クロアチア(招待講演)
    • Year and Date
      2010-09-04
    • Data Source
      KAKENHI-PROJECT-22249005
  • [Presentation] UV-induced mutations in the epidermal genome of DNA polymerase η- and ι-deficient mice occurring in vivo.2009

    • Author(s)
      Hanaoka, F.
    • Organizer
      Second Erling Seeberg Symposium on DNA Repair, Keynote Address
    • Place of Presentation
      Alesund and Geiranger, Nnrwav
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Presentation] DNA研究の将来(財)ライフサイエンス振興財団2009

    • Author(s)
      花岡文雄
    • Organizer
      25周年記念シンポジウム-ライフサイエンスの輝かしい未来-
    • Place of Presentation
      東京
    • Year and Date
      2009-03-04
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Presentation] UV-induced mutations in the epidermal genome of DNA polymerase eta- and iota-deficient mice occurring in vivo.2009

    • Author(s)
      Fumio Hanaoka
    • Organizer
      Seeberg Symposium 2009
    • Place of Presentation
      Aalesund, Norway
    • Year and Date
      2009-06-20
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Presentation] UV-induced mutations in the epidermal genome of TLS polymerase-deficient mice.2009

    • Author(s)
      Hanaoka, F.
    • Organizer
      The 40^<th> International Symposium of the Princess Takamatsu Cancer Research Fund
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Presentation] ゲノム情報維持の分子機構に関する研究2009

    • Author(s)
      花岡文雄
    • Organizer
      日本薬学会第129年会日本薬学会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Presentation] UV-induced mutations in the epidermal genome of TLS polymerase-deficient mice2009

    • Author(s)
      Hanaoka, F
    • Organizer
      The 40th International Symposium of the Princess Takamatsu Cancer Research Fund
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Presentation] 損傷を乗り越えるポリメラーゼの機能と発癌の制御2009

    • Author(s)
      花岡文雄
    • Organizer
      東北大学・加齢医学研究所・シンポジウム平成20年度・ゲノムリサーチセンター・ワークショップ「癌と老化を乗り越えるDNA修復の科学」
    • Place of Presentation
      仙台
    • Year and Date
      2009-03-13
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Presentation] ゲノム情報維持の分子機構に関する研究2009

    • Author(s)
      花岡文雄
    • Organizer
      日本薬学会第129年会日本薬学会賞受賞講演
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Presentation] 損傷を乗り越えるポリメラーゼの機能と発癌の制御東北大学・加齢医学研究所・シンポジウム2009

    • Author(s)
      花岡文雄
    • Organizer
      平成20年度・ゲノムリサーチセンター・ワークショップ「癌と老化を乗り越えるDNA修復の科学」
    • Place of Presentation
      仙台
    • Year and Date
      2009-03-13
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Presentation] UV-induced mutations in the epidermal genome of DNA polymeraseη- andι-deficient mice occurring in vivo2009

    • Author(s)
      Hanaoka, F
    • Organizer
      Second Erling Seeberg Symposium on DNA Repair, Keynote Address
    • Place of Presentation
      Alesund and Geiranger, Norway
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Presentation] 損傷乗り越え複製とがん2008

    • Author(s)
      花岡文雄
    • Organizer
      第67回日本癌学会学術総会、モーニング・レクチャー
    • Place of Presentation
      名古屋
    • Year and Date
      2008-10-29
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Presentation] 損傷乗り越え型DNAポリメラーゼ・イータおよびイオタ欠損マウスの皮膚における紫外線誘発発がんと突然変異2008

    • Author(s)
      花岡文雄
    • Organizer
      日本放射線影響学会第51回大会
    • Place of Presentation
      北九州
    • Year and Date
      2008-11-19
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Presentation] 損傷乗り越え型DNAポリメラーゼ・イータおよびイオタ欠損マウスの皮膚における紫外線誘発発がんと突然変異2008

    • Author(s)
      花岡文雄
    • Organizer
      日本放射線影響学会第51回大会、シンポジウム「放射線発がんの基盤を形成する遺伝子・細胞・組織の応答」
    • Place of Presentation
      北九州
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Presentation] 損傷乗り越え複製研究の最前線2008

    • Author(s)
      花岡文雄
    • Organizer
      東京都臨床医学総合研究所
    • Place of Presentation
      東京
    • Year and Date
      2008-12-19
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Presentation] Schizosaccharomyces pombe Ddbl recruits substrate-specific adaptor proteins through a novel protein motif, the DDB-box.2008

    • Author(s)
      Fukumoto, Y., Dohmae, N., Hanaoka, F.
    • Organizer
      The 6th 3R Symposium (3R Symposium 2008)
    • Place of Presentation
      掛川
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Presentation] Translesion synthesis and cancer.2008

    • Author(s)
      Hanaoka, F.
    • Organizer
      Clare Hall Laboratories, Cancer Research UK
    • Place of Presentation
      South Mimms, UK
    • Year and Date
      2008-07-25
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Presentation] 損傷乗り越え複製とがん2008

    • Author(s)
      花岡文雄
    • Organizer
      第67回日本癌学会学術総会、モーニング・レクチャー
    • Place of Presentation
      名古屋
    • Year and Date
      2008-10-29
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Presentation] Translesion synthesis and cancer2008

    • Author(s)
      Hanaoka, F
    • Organizer
      Clare Hall Laboratories, Cancer Research UK
    • Place of Presentation
      South Mimms, UK
    • Year and Date
      2008-07-25
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Presentation] In vivo and in vitro studies on DNA polymerase eta2008

    • Author(s)
      Hanaoka, F
    • Organizer
      Gordon Research Conference on Mutagenesis
    • Place of Presentation
      Oxford, UK
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Presentation] Schizosaccharomyces pombe Ddb1 recruits substrate-specific adaptor proteins through a novel protein motif, the DDB-box2008

    • Author(s)
      Fukumoto, Y., Dohmae, N., Hanaoka, F.
    • Organizer
      The 6th 3R Symposium (3R Symposium 2008
    • Place of Presentation
      掛川
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Presentation] In vivo and in vitro studies on DNA polymerase eta.2008

    • Author(s)
      Hanaoka, F.
    • Organizer
      Gordon Research Conference on Mutagenesis
    • Place of Presentation
      Oxford, UK
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Presentation] 損傷乗り越え型DNAポリメラーゼ・イータおよびイオタ欠損マウスの皮膚における紫外線誘発発がんと突然変異2008

    • Author(s)
      花岡文雄
    • Organizer
      日本放射線影響学会第51回大会、シンポジウム「放射線発がんの基盤を形成する遺伝子・細胞・組織の応答」
    • Place of Presentation
      北九州
    • Year and Date
      2008-11-19
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Presentation] 損傷乗り越え複製研究の最前線2008

    • Author(s)
      花岡文雄
    • Organizer
      東京都臨床医学総合研究所
    • Place of Presentation
      東京
    • Year and Date
      2008-12-09
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Presentation] DNA repair and ubiquitin.2007

    • Author(s)
      Hanaoka, F.
    • Place of Presentation
      Ohio State University Medical Center, Columbus, Ohio, USA(招待講演)
    • Year and Date
      2007-05-18
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Presentation] 損傷乗り越え複製の分子機構-DNAポリメラーゼ・イータを中心に-2007

    • Author(s)
      花岡文雄、横井雅幸、大雲剛志、金尾梨絵、赤木純一、益谷央豪
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会大会合同大会(BMB2007)、シンポジウム「DNA修復研究の最前線」
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Presentation] Defective translesion DNA synthesis and links to human disease.2007

    • Author(s)
      Hanaoka, F.
    • Organizer
      9th Annual Midwest DNA Repair Symposium, Keynote Lecture
    • Place of Presentation
      Columbus, Ohio
    • Year and Date
      2007-05-20
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Presentation] 損傷乗り越え複製の分子機構-DNAポリメラーゼ・イータを中心に-2007

    • Author(s)
      花岡文雄, ほか
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学大会合同大会
    • Place of Presentation
      横浜
    • Year and Date
      2007-12-13
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Presentation] Translesion synthesis and cancer.2007

    • Author(s)
      Hanaoka, F.
    • Organizer
      7th Joint Conference of the American Association for Cancer Research and the Jananese Cancer Association.
    • Place of Presentation
      Waikoloa, Hawaii, USA
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Presentation] DNA損傷乗り越え複製と発がん2007

    • Author(s)
      花岡文雄
    • Organizer
      がん特定研究否同シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2007-02-23
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Presentation] 損傷轍複製とがん2007

    • Author(s)
      花岡文雄、益谷央豪、塚本徹哉、立松正衛
    • Organizer
      第66回日本癌学会学術総会、シンポジウム「ゲノム不安定性」
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Presentation] TLS polymerase deficiencies and cancer2007

    • Author(s)
      Hanaoka, F
    • Organizer
      The 3rd Japan-US DNA Repair Meeting
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Presentation] TLS polymerase deficiencies and cancer.2007

    • Author(s)
      Hanaoka, F.
    • Organizer
      The 3rd Japan-US DNA Repair Meeting
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Presentation] DNA repair and ubiquitin.2007

    • Author(s)
      Hanaoka, F.
    • Organizer
      Ohio State University Medical Center
    • Place of Presentation
      Columbus, Ohio, USA
    • Year and Date
      2007-05-18
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Presentation] Recent studies on mammalian DNA polymerase eta2007

    • Author(s)
      Hanaoka, F.
    • Organizer
      the product of XP variant responsible gene. Mayo Clinic
    • Place of Presentation
      Rochester, Minnesota, USA
    • Year and Date
      2007-05-21
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Presentation] 損傷乗り越え複製とがん2007

    • Author(s)
      花岡文雄、益谷央豪、塚本徹哉、立松正衛
    • Organizer
      第66回日本癌学会学術総会、シンポジウム「ゲノム不安定性」
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Presentation] Recent studies on mammalian DNA polymerase eta, the product of XP variant responsible gene2007

    • Author(s)
      Hanaoka, F
    • Organizer
      Mayo Clinic
    • Place of Presentation
      Rochester, Minnesota, USA
    • Year and Date
      2007-05-21
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Presentation] 損傷乗り越え複製の分子機構-DNAポリメラーゼ・イータを中心に-2007

    • Author(s)
      花岡文雄、横井雅幸、大雲剛志、金尾梨絵、赤木純一、益谷央豪
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会大会合同大会(BMB2007)、シンポジウム「DNA修復研究の最前線」
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Presentation] Defective translesion DNA synthesis and links to human disease.2007

    • Author(s)
      Hanaoka, F.
    • Organizer
      9th Annual Midwest DNA Repair Symposium, Keynote Lecture
    • Place of Presentation
      Columbus, Ohio
    • Year and Date
      2007-05-20
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Presentation] 損傷乗り越え複製の分子機構-DNAポリメラーゼ・イータを中心に-2007

    • Author(s)
      花岡文雄, ほか
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
    • Place of Presentation
      横浜
    • Year and Date
      2007-12-13
    • Data Source
      KAKENHI-PROJECT-19209003
  • [Presentation] In vivo and in vitro studies on DNA polymerase eta, the product of XP variant gene.2006

    • Author(s)
      Hanaoka, F.
    • Organizer
      The First International Symposium on the MEXT Priority Research Project.-The Chromosome Cycle-.
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Presentation] 紫外線障害修復機構-その概要とXPV遺伝子欠損ラウスを用いた皮膚発がん実験について-2006

    • Author(s)
      花岡文雄
    • Organizer
      第28回日本光医学・光生物学会
    • Place of Presentation
      徳島
    • Year and Date
      2006-07-07
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Presentation] In vivo and in vitro studies on mammalian DNA polymerase eta, the product of XP-V responsible gene.2006

    • Author(s)
      Hanaoka, F.
    • Organizer
      Erling Seeberg Symposium on DNA Repair.
    • Place of Presentation
      Bodo and Henningsver, Lofoten, Norway
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Presentation] 遺伝盾報を保持するしくみ2006

    • Author(s)
      花岡文雄
    • Organizer
      第16回遺伝医学セミナー
    • Place of Presentation
      大阪
    • Year and Date
      2006-09-02
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Presentation] 色素性乾皮症バリアント群の解析から明らかにった新規DNA損傷応答について2006

    • Author(s)
      花岡文雄
    • Organizer
      山泉克教授追悼講演会「DNA傷害と修復応答」
    • Place of Presentation
      熊本
    • Year and Date
      2006-07-21
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Presentation] DNA修復におけるユビキチン化の役割2006

    • Author(s)
      花岡文雄
    • Organizer
      千里ライフサイエンスセミナー「蛋白質の修飾と機能制御」
    • Place of Presentation
      大阪
    • Year and Date
      2006-07-05
    • Data Source
      KAKENHI-PROJECT-17013053
  • [Presentation] Defective translesion DNA synthesis and links to human disease.

    • Author(s)
      Hanaoka F
    • Organizer
      International Symposium on Xeroderma Pigmentosum and Related Diseases: Disorders of DNA Damage Response -Bench to Bedside-
    • Place of Presentation
      神戸
    • Year and Date
      2014-03-05 – 2014-03-07
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-22131001
  • [Presentation] Role of DNA polymerase eta in somatic hypermutation.

    • Author(s)
      Hanaoka F
    • Organizer
      3rd France-Japan Cancer Meeting
    • Place of Presentation
      Toulouse, France
    • Year and Date
      2013-11-20 – 2013-11-23
    • Invited
    • Data Source
      KAKENHI-PLANNED-22131008
  • [Presentation] Functional roles of TLS polymerases in mouse skin upon UV irradiation.

    • Author(s)
      Hanaoka F
    • Organizer
      Gordon Research Conference on Mammalian DNA Repair
    • Place of Presentation
      Ventura, California, USA
    • Year and Date
      2015-02-08 – 2015-02-13
    • Invited
    • Data Source
      KAKENHI-PLANNED-22131008
  • [Presentation] DNAポリメラーゼ・イータ ―その構造と多彩な機能―

    • Author(s)
      花岡文雄
    • Organizer
      新学術領域研究「遺伝情報場」公開シンポジウム
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PLANNED-22131008
  • [Presentation] 損傷トレランスと突然変異生成に働く損傷乗り越え合成ポリメラーゼ

    • Author(s)
      花岡文雄
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本
    • Year and Date
      2014-03-28 – 2014-03-30
    • Invited
    • Data Source
      KAKENHI-PLANNED-22131008
  • [Presentation] 損傷トレランスと突然変異生成に働く損傷乗り越え合成ポリメラーゼ

    • Author(s)
      花岡文雄
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本
    • Year and Date
      2014-03-28 – 2014-03-30
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-22131001
  • [Presentation] DNAポリメラーゼ・イータ ―その構造と多彩な機能―

    • Author(s)
      花岡文雄
    • Organizer
      新学術領域研究「遺伝情報場」公開シンポジウム
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-22131001
  • [Presentation] Roles of translesion synthesis polymerases eta and iota in UV-induced mutagenesis in mice

    • Author(s)
      Sakurai Y, Yokoi M, Murakumo Y, Hanaoka F
    • Organizer
      ZING Conferences DNA Polymerases: Biology, Diseases and Biomedical Applications Conference 2014
    • Place of Presentation
      Cambridge, UK
    • Year and Date
      2014-08-31 – 2014-09-04
    • Invited
    • Data Source
      KAKENHI-PLANNED-22131008
  • [Presentation] Roles of DNA polymerases eta and iota in UV-induced mutagenesis.

    • Author(s)
      Sakurai Y, Yokoi M, Hanaoka F
    • Organizer
      5th US-Japan DNA Repair Meeting
    • Place of Presentation
      鳴門、徳島
    • Year and Date
      2014-10-28 – 2014-10-31
    • Invited
    • Data Source
      KAKENHI-PLANNED-22131008
  • [Presentation] 損傷トレランス研究の40年:SOS応答から損傷乗り越えポリメラーゼへ

    • Author(s)
      花岡文雄
    • Organizer
      第36回日本光医学・光生物学会
    • Place of Presentation
      大阪
    • Year and Date
      2014-07-25 – 2014-07-26
    • Invited
    • Data Source
      KAKENHI-PLANNED-22131008
  • [Presentation] Role of DNA polymerase eta in somatic hypermutation.

    • Author(s)
      Hanaoka F
    • Organizer
      3rd France-Japan Cancer Meeting
    • Place of Presentation
      Toulouse, France
    • Year and Date
      2013-11-20 – 2013-11-23
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-22131001
  • [Presentation] Roles of mammalian DNA polymerases eta and iota in UV-induced mutagenesis.

    • Author(s)
      Hanaoka F, Sakurai Y, Yokoi M
    • Organizer
      The 9th 3R Symposium
    • Place of Presentation
      御殿場
    • Year and Date
      2014-11-17 – 2014-11-21
    • Invited
    • Data Source
      KAKENHI-PLANNED-22131008
  • [Presentation] DNAポリメラーゼ・イータ ―その構造と多彩な機能―

    • Author(s)
      花岡文雄
    • Organizer
      新学術領域研究「遺伝情報場」公開シンポジウム
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-22249005
  • [Presentation] Defective translesion DNA synthesis and links to human disease.

    • Author(s)
      Hanaoka F
    • Organizer
      International Symposium on Xeroderma Pigmentosum and Related Diseases: Disorders of DNA Damage Response -Bench to Bedside-
    • Place of Presentation
      神戸
    • Year and Date
      2014-03-05 – 2014-03-07
    • Invited
    • Data Source
      KAKENHI-PLANNED-22131008
  • 1.  TANAKA Kiyoji (80144450)
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    # of Collaborated Products: 1 results
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    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
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  • 28.  竹石 桂一 (90012608)
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  • 34.  瀬野 悍二 (30076989)
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  • 35.  金田 澄子 (60152815)
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  • 36.  杉野 明雄 (90231737)
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  • 37.  小笠原 直毅 (10110553)
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  • 38.  宇井 理生 (50001037)
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  • 39.  黒瀬 等 (10183039)
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  • 40.  堅田 利明 (10088859)
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  • 41.  HIROHASHI Setsuo (70129625)
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  • 42.  小田 鈎一郎 (40012736)
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  • 44.  HORIUCHI Takashi (60108644)
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  • 45.  ISHIKAWA Fuyuki (30184493)
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  • 46.  YAMAMOTO Masayuki (50166823)
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  • 47.  NAKAMURA Takuro (00180373)
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  • 48.  SHIMOTONO Kunitada (10000259)
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  • 49.  OGAWA Hideyuki (70028207)
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  • 50.  新井 賢一 (00012782)
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  • 53.  西本 毅治 (10037426)
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  • 54.  森川 耿右 (80012665)
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  • 55.  HOEIJMAKERS ヤン
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  • 61.  IWAI Shigenori (10168544)
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  • 64.  SEKI Masayuki (70202140)
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  • 68.  IDE Hiroshi (30223126)
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  • 69.  AKAGI Jun-ichi (60512556)
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  • 78.  OGI Tomoo (80508317)
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  • 126.  THOMALE J.
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  • 129.  BOHR Vilhelm A.
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  • 130.  HOEIJMAKERS Jan H.J.
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  • 132.  MATSUMOTO Syota
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  • 133.  SEKIMOTO Takayuki
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  • 134.  KANAO Rie
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  • 137.  青田 聖恵
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  • 138.  小林 純也
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  • 139.  今本 尚子
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    # of Collaborated Products: 1 results
  • 140.  白川 昌宏
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    # of Collaborated Products: 1 results

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