Yasui Akira 安井明

… Alternative Names

安井明ヤスイアキラ

YASUI Akira 安井明

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Researcher Number	60191110
Other IDs
Affiliation (Current)	2023: 東北大学, 加齢医学研究所, 加齢研フェロー
Affiliation (based on the past Project Information) *help	2019 – 2021: 東北大学, 加齢医学研究所, 加齢研フェロー 2017: 東北大学, 加齢医学研究所, 教授 2016 – 2017: 東北大学, 加齢医学研究所, 加齢研フェロー 1993 – 2015: 東北大学, 加齢医学研究所, 教授 1996: 大阪大学, 加齢医学研究所, 教授 … More 1996: 東北大学, 加齡医学研究所, 教授 1993: 東北大学, 加齢医学研究所・神経機能情報研究分野, 助手 1993: Inst.Develop.Aging Cancer, Dept.Neurochem.Mol.Biol.Professor, 神経機能情報研究分野, 教授 1992: 東北大学, 抗酸研, 助手 1992: 東北大学抗酸菌病研究所, 薬理学研究部門, 助手 1988 – 1992: 東北大学, 抗酸菌病研究所, 助手 1989 – 1990: 東北大学, 抗酸菌病研究所・薬理学部門, 助手 Less
Review Section/Research Field	Principal Investigator Biological Sciences / 環境影響評価(含放射線生物学) / Risk sciences of radiation/Chemicals / Risk sciences of radiation and chemicals / 分子遺伝学・分子生理学 Except Principal Investigator Cell biology / Biological Sciences / Experimental pathology / Molecular biology / Basic Section 49030:Experimental pathology-related … More / 応用薬理学・医療系薬学 / 広領域 / 植物生理 / 放射線5生物学 / Tumor biology / Risk sciences of radiation/Chemicals / General medical chemistry Less
Keywords	Principal Investigator DNA修復 / DNA repair / 活性酸素 / 単鎖切断 / DNA損傷 / 癌治療 / DNA damage / 老化 / 二重鎖切断 / 発癌 … More / 細胞老化 / XRCC1 / PARP / DNA切断 / APエンドヌクレアーゼ / DNA単鎖切断 / 塩基損傷 / ポリADPリボシル化 / 塩基除去修復 / photo repair / circadian rhythm / ノックアウトマウス / 相同組換え / クロマチンリモデリング / ARID1A / 癌化 / プロテオミクス / 可視化解析 / 除去修復 / 細胞死 / ミトコンドリア / 紫外線 / NHEJ / シスプラチン / BAF complex / SWI/SNF / 細胞癌化 / ARID1B / BAF複合体 / ヌクレオゾームリモデリング / Aging / cancer / DNA strand breaks / proteomics / visual analysis / reactive oxygen species / リアルタイム解析 / 放射線 / レーザー / 生体分子 / 癌 / 可視化 / glycosylase / oxidative DNA damage / base excision repair / チミングリコール / UVDE / 発がん / グリコシラーゼ / 活性酸素DNA修復 / excision repair / DNA break / 紫外線損傷 / repair deficient mouse / gene targeting / 青色光受容体 / ジーンターゲーティング / サーカディアンリズム / 光回復酵素 / 光回復 / 日周リズム / 修復欠損マウス / ジーンターゲッティング / DNA binding protein / DNA damages / protein structure / 結晶化 / 遺伝子 / 遺伝情報 / 分子生物学 / 修復酵素 / DNA結合蛋白質 / 蛋白質の構造 / エンド/エキソヌクレアーゼ / ポリADPリボースポリメラーゼ / ポリADPリボシレーション / Homologous recombination / MMS / Poly(ADP-ribosyl)ation / PARP1 / single-strand break / 非相同末端結合 / 蛋白可視化 / DNA二重鎖切断 / 転写 / transcription and repair / Ubiquitination / Polycomb / ENL / transcription / chromatin remodeling / ポリADPリボース / in situ解析 / PALF / ゲノム不安定性 / 乳がん / トウスジュニックマウス / 遺伝子破壊 / 遺伝子組換え / ミトユンドリアDNA / 活性酵素 / 分子生物前 / cDNAクローン / ライブラリー / 蛋白質 / フアンコーニ=アネーミア / DNAクロスリンク … More Except Principal Investigator DNA修復 / DNA repair / 色素性乾皮症 / ノックアウトマウス / 発がん / xeroderma pigmentosum / 紫外線 / コケイン症候群 / 転写 / 突然変異 / Cockayne syndrome / knockout mice / gene targeting / 遺伝子ターゲティング / 生物時計 / 糖尿病 / 体内時計 / 分化転換 / 脱分化 / 膵β細胞 / 細胞分裂 / 染色体分配 / 除去修復 / 光回復酵素 / DNA損傷 / 膵癌 / 膵癌前駆病変 / DNA複製 / cAMP / 光受容分子 / 細胞死 / 概日リズム / 時計遺伝子 / 膵島 / 染色体 / 細胞・組織 / 癌 / 微小管 / キネトコア / 細胞周期 / 光回復 / 皮膚癌 / ミスマッチ修復 / 遺伝子クローニング / 遺伝病 / 相同的組換え / 組換え修復 / 遺伝子ターゲッティング / 光形態形成 / 光合成 / 視覚 / 遺伝子操作 / 癌の単一細胞起源 / 放射線の作用 / DNA修復遺伝子 / クリプトクロム / 浸潤性膵管癌前癌病変 / KPNA2 / 亜鉛結合不全CRY1 / 前癌病変 / 膵島内膵管異型細胞 / リプログラミング / 小胞体ストレス (ERストレス) / TFF2 (Trefoil factor 2) / RGSタンパク質 / 脱分化 (dedifferentiation) / 膵β細胞-膵管細胞分化転換 / 亜鉛 / 亜鉛結合不全型CRY1 / 膵δ細胞 / 上皮間葉転換 / 複製 / ＤＮＡ修復 / ゲノム再編 / 国際発信 / 領域運営 / クロマチンリモデリング / ヒストン修飾 / ゲノム / 摂食同調振動体 / 視交叉上核 / 組織リモデリング / HES1 / クリプトクロム(CRY) / 膵管上皮細胞 / 膵β細胞新生 / tubular complex / 膵上皮内腫瘍性病変（PanIN） / 繊維化 / 膵管細胞 / 膵上皮内腫瘍性病変 (PanIN) / CRY1亜鉛結合モチーフ配列 / 亜鉛結合変異mCRY1(C414A-CRY1) / 膵β細胞-膵管細胞分化転換 / KPNA2（インポーティンα1） / 膵上皮内腫瘍性病変(PanIN) / 膵島構造リモデリング / 細胞老化関連分泌形質(SASP) / Angiogenesis / Membrane Transporter / Metastasis / Cancer Chemotherapy / 膜輸送体 / 癌化学治療法 / 血管新生 / 膜輸送 / 転移 / 癌化学療法 / loss of heterozygosity / alpha-particles / angiosarcoma / liver / human / Thorotrast / internal exposure / radiation carcinogenesis / ヘテロ接合性の消失(LOH) / 細胆管癌 / 肝細胞癌 / 肝内胆管癌 / ヘテロ接合性消失 / α線被ばく / 血管肉腫 / 肝 / ヒト / トロトラスト / 内部被ばく / 放射線発癌 / transcription / nuclear matrix / postreplication repair / DNA damage / リン酸化 / NTH1 / XPA / 転写伸長 / チミングリコール / DNA修復ネットワーク / 核マトリクス / 複製後修復 / DNA損傷トレランス / 損傷乗り越え修復 / 機能的プロテオーム / ユビキチンリガーゼ / 損傷トレランス / レーザー / ユビキチンリカーゼ / 損傷乗り越え複製 / ユビキチン化 / 熱力学 / ゲノム全体の修復 / 転写と共役した修復 / skin cancer / ultraviolet light / microinjection / trascription / 免疫グロブリン / アルキル化剤 / 基本転写 / マイクロインジェクション / Ion channls / Signal transduction systems / Cryptochromes / Algae / Flavins / Photoreceptor systems / Blue light / プロトプラスト / レチノクロム / アデニル酸シクラーゼ / 粘菌 / 青色光反応 / プテリン / ラン藻 / UV-A光 / イオンチャネル / 信号伝達系 / クリプトクローム / 藻類 / フラビン / 光受容分子系 / 青色光 / Genetic disease / Carcinogenesis / Mutagenesis / Homologous recombination / Recombination repair / Nucleotide excision repair / 相同的組換之 / 組換之修復 / photoreactivation / ultraviolet / Yeast homolog / two hybrid system / エンドヌクレアーゼ / RPA / Znフィンガー / DNA結合能 / 2ハイブリドシステム / 酵母ホモログ / αハイブリドシステム / mismatch repair / X-ray crystallography / photolyases / gene cloning / DNA結合 / モデルマウス / 活性酸素 / p53蛋白質 / X線構造解析 / restriction length polymorphism / threshold-like response / X chromosome inactivation / germ cell mutation / UV skin cancer / excision repair / photolyase / DNA strand break / 胸腺腫 / 閾値様反応 / ユビキチン活性化酵素 / 紫外線損傷 / 除去修復遺伝子 / DNA二本鎖切断修復 / クローナリティ / しきい線量 / 制限酵素断片長多型 / しきい値様反応 / X染色体不活性化 / 生殖細胞突然変異 / 紫外線皮膚癌 / DNA鎖切断 / フィトクロム / 視物質 / 抗がん剤耐性 / がん治療 / インスリン / MODY / SASP / インスリン分泌 / サーカディアンリズム / ヘッジホッグ / 膵α細胞 / 給餌同調振動体（FEO) / 視交叉上核（SCN) / ヘッジホッグシグナル伝達経路 / 細胞老化 / mCRY1亜鉛結合部位 (Cys414残基) / 染色体不安定性 / 紡錘体 / 細砲分裂 / 紡錘体チェックポイント / 交差耐性 / 化学療法 / 二次癌 / 放射線治療 / 放射線耐性 / モデル動物 / 固体寿命 / 遺伝性素因 / 高齢者の疫学ゲノム / 老化制御 / 寿命変異体 / 寿命遺伝子 / 健康寿命 / APエンドヌクレアーゼ / 塩基除去修復 / マクレオチド除去修復 / p53 / プロテアソーム / HNPCC / 酸化的DNA損傷 / 減数分裂 / 遺伝子発現制御 / 遺伝情報維持 / 骨格筋分化 / タンパク質ホスファタ-ゼ / 分子生物学 / メッセンジャ-RNA / 細胞分化 / 蛋白質ホスファタ-ゼ / 染色体異常 / 発癌機構 / 突然変異誘発 / キメラ蛋白質 / 光制御 / 光受容 / 染色体損傷 / 発癌の機構 / 突然変異誘発機構 Less

A new approach to the pathogenesis of pancreatic cancer and the disorders of circadian rhythm based on the analysis of CRY1-binding proteins
- Principal Investigator
  
  Okano Satoshi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Yamagata University
Elucidation the roles of senescence-like phenotype in pancreatic beta-cells in diabetic mutant cryptochrome1 transgenic mice
- Principal Investigator
  
  Okano Satoshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Yamagata University
Functions of BAF complex in DNA repair and cancer therapyPrincipal Investigator
- Principal Investigator
  
  YASUI Akira
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Tohoku University
Maintenance of chromosomal stability by efficient chromosome alignment
- Principal Investigator
  
  Tanaka Kozo
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cell biology
- Research Institution
  Tohoku University
Cellular response to DNA single-strand break and its repairPrincipal Investigator
- Principal Investigator
  
  YASUI Akira
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Tohoku University
Regulatory system of chromosomal stability by molecules including a novel molecule, CAMP
- Principal Investigator
  
  TANAKA Kozo
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cell biology
- Research Institution
  Tohoku University
Elucidation of molecular mechanisms of unusual circadian locomotor behavior and non-obese early onset diabetes mellitus in mutant (Cys414-Ala) cryptochrome1 transgenic mice
- Principal Investigator
  
  OKANO Satoshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Yamagata University
Basic research to overcome resistance to anti-mitotic drugs
- Principal Investigator
  
  TANAKA Kozo
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor biology
- Research Institution
  Tohoku University
Visualization and proteomics of chromatin remodeling in DNA damage responsePrincipal Investigator
- Principal Investigator
  
  YASUI Akira
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
Replication, repair and transcription; coupling mechanisms and chromatin dynamics for genome integrity
- Principal Investigator
  
  Hanaoka Fumio
- Project Period (FY)
  2010 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Gakushuin University
Molecular network supporting chromosomal stability
- Principal Investigator
  
  TANAKA Kozo
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  Tohoku University
紡錘体チェックポイントによる染色体分配制御ネットワークの解明
- Principal Investigator
  
  TANAKA Kouzo
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
Novel DNA damage responses and repair regulated by poly-ADP ribosylation and chromatin remodelingPrincipal Investigator
- Principal Investigator
  
  YASUI Akira
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Tohoku University
ゲノム単鎖切断に関わるゲノム不安定性と細胞死Principal Investigator
- Principal Investigator
  
  安井明
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
長期放射線被ばくの細胞影響および耐性機構解明へ向けた基礎的研究
- Principal Investigator
  
  FUKUMOTO Manabu
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Tohoku University
Live cell analysis of cellular responses to various types of DNA damage induced by reactive oxygenPrincipal Investigator
- Principal Investigator
  
  YASUI Akira
- Project Period (FY)
  2004 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Tohoku University
健康寿命の遺伝素因の解明と延長のための戦略的研究
- Principal Investigator
  
  白澤卓二
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Tokyo Metropolitan Institute of Gerontology
Molecular genetic mechanism of alpha-parficle induced human cancers : Analysis of liver carcinogenesis in Thorotrast patients.
- Principal Investigator
  
  FUKUMOTO Manabu
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  広領域
- Research Institution
  Tohoku University
Expression of targets for chemotherapy in primacy and metastatic cancer
- Principal Investigator
  
  TAKEBAYASHI Yuji
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  FUKUSHIMA MEDICAL UNIVERSITY
  Tohoku University
Repair of oxidative DNA damage in Mammalian cellsPrincipal Investigator
- Principal Investigator
  
  YASUI Akira
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  Tohoku University
塩基損傷・単鎖切断の修復ネットワークと細胞死Principal Investigator
- Principal Investigator
  
  安井明
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
ヒト細胞での遺伝子破壊系の開発とゲノム機能解析への応用Principal Investigator
- Principal Investigator
  
  安井明
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
DNA damage-induced cell death and DNA repair network
- Principal Investigator
  
  TANAKA Kiyoji
- Project Period (FY)
  2000 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Study of DNA repair deficient micePrincipal Investigator
- Principal Investigator
  
  YASUI Akira
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  Tohoku University
Study of cellular responses to single-strand breakPrincipal Investigator
- Principal Investigator
  
  YASUI Akira
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  Tohoku University
Transcription-coupled repair and its deficiency
- Principal Investigator
  
  TANAKA Kiyoji
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  Molecular biology
- Research Institution
  Osaka University
DNA除去修復機構とその修復欠損の分子病態
- Principal Investigator
  
  田中亀代次
- Project Period (FY)
  1996 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Osaka University
Molecular Mechanisms of Genomic Instability and DNA Repair
- Principal Investigator
  
  HANAOKA Fumio
- Project Period (FY)
  1996 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Osaka University
Structural and Functional Analyses of Blue Light Photoreceptor Systems
- Principal Investigator
  
  WATANABE Masakatsu
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  植物生理
- Research Institution
  Okazaki National Research Institutes
DNA修復欠損の分子病態
- Principal Investigator
  
  花岡文雄
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  Molecular biology
- Research Institution
  Osaka University
Molecular Dissection of Human DNA Excision Repair Genes
- Principal Investigator
  
  TANAKA Kiyoji
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Osaka University
Structure and function of DNA repair enzymesPrincipal Investigator
- Principal Investigator
  
  YASUI Akira
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
Molecular Mechanism for Maintainance of Genetic Information
- Principal Investigator
  
  TANAKA Kiyoji
- Project Period (FY)
  1993 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
遺伝情報維持の分子機構
- Principal Investigator
  
  田中亀代次
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Institution
  Osaka University
融合蛋白質バンクの作成とそれを用いた蛋白質間相互作用の研究Principal Investigator
- Principal Investigator
  
  安井明
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  分子遺伝学・分子生理学
- Research Institution
  Tohoku University
Studies on expression of radiation damage and modifying repair mechanisms
- Principal Investigator
  
  SATO Kouki
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  放射線5生物学
- Research Institution
  National Institute of Radiological Sciences
細胞増殖の調節、癌細胞の形質保持における蛋白質ホスファタ-ゼの機能に関する研究
- Principal Investigator
  
  田村眞理
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Tohoku University
細胞増殖の調節、癌細胞の形質保持における蛋白質ホスファタ-ゼの機能に関する研究
- Principal Investigator
  
  田村真理
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Hirosaki University
DNAクロスリンクの修復とフアンコーニ・アネーミアの解析Principal Investigator
- Principal Investigator
  
  安井明
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Tohoku University
光受容関連分子の遺伝子操作による研究
- Principal Investigator
  
  徳永史生
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
発がんにおけるDNA損傷の発現および細胞起源
- Principal Investigator
  
  田ノ岡宏
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
発がんにおけるDNA損傷の発現および細胞起源
- Principal Investigator
  
  田ノ岡宏
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
光受容関連分子の遺伝子操作による研究
- Principal Investigator
  
  徳永史生
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University

[Journal Article] Karyopherin Alpha 2-Expressing Pancreatic Duct Glands and Intra-Islet Ducts in Aged Diabetic C414A-Mutant-CRY1 Transgenic Mice2019
- Author(s)
  Okano S, Yasui A, Kanno SI, Satoh K, Igarashi M, Nakajima O
- Journal Title
  
  Journal of Diabetes Research
  
  Volume: Volume 2019 Pages: 7234549-7234549
- DOI
  10.1155/2019/7234549
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07498
[Journal Article] Nucleosome remodelling, DNA repair and transcriptional regulation build negative feedback loops in cancer and cellular ageing2017
- Author(s)
  Watanabe Reiko、Kanno Shin-ichiro、Mohammadi Roushandeh Amaneh、Ui Ayako、Yasui Akira
- Journal Title
  
  Philos Trans R Soc Lond B Biol Sci
  
  Volume: 372 Issue: 1731 Pages: 0473-0473
- DOI
  10.1098/rstb.2016.0473
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19615, KAKENHI-PROJECT-15H01737
[Journal Article] Nucleosome remodeling, DNA repair and transcriptional regulation build negative feedback loops in cancer and cellular aging.2017
- Author(s)
  Watanabe R, Kanno S, Mohammadi Roushandeh A, Ui A, and Yasui A
- Journal Title
  
  Philos Trans Biology
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H01737
[Journal Article] ALC1/CHD1L, a chromatin-remodeling enzyme, is required for efficient base excision repair.2017
- Author(s)
  Tsuda M, Cho K, Ooka M, Shimizu N, Watanabe R, Yasui A, Nakazawa Y, Ogi T, Harada H, Agama K, Nakamura J, Asada R, Fujiike H, Sakuma T, Yamamoto T, Murai J, Hiraoka M, Koike K, Pommier Y, Takeda S, Hirota K.
- Journal Title
  
  PLos One
  
  Volume: 12 Issue: 11 Pages: e0188320-e0188320
- DOI
  10.1371/journal.pone.0188320
- NAID
  120006800808
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05333, KAKENHI-PUBLICLY-16H01314, KAKENHI-PROJECT-16H06306, KAKENHI-PROJECT-15H01737, KAKENHI-PROJECT-17H00783, KAKENHI-PROJECT-16H02957, KAKENHI-PROJECT-16J02252, KAKENHI-PROJECT-16K12598, KAKENHI-PROJECT-16K18478, KAKENHI-PROJECT-17H01877
[Journal Article] Ubiquitylation of Ku80 by RNF126 Promotes Completion of Nonhomologous End Joining-Mediated DNA Repair.2017
- Author(s)
  Ishida N, Nakagawa T, Iemura SI, Yasui A, Shima H, Katoh Y, Nagasawa Y, Natsume T, Igarashi K, Nakayama K.
- Journal Title
  
  Mol Cell Biol
  
  Volume: 37 Issue: 4
- DOI
  10.1128/mcb.00347-16
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H01737, KAKENHI-PROJECT-26293059, KAKENHI-PROJECT-16K14664, KAKENHI-PROJECT-15K18365, KAKENHI-PROJECT-17K10432
[Journal Article] DNA polymerase beta participates in mitochondrial DNA repair.2017
- Author(s)
  Sykora P, Kanno S, Akbari M, Kulikowicz T, Baptiste BA, Leandro G, Lu H, Tian J, May A, Becker KA, Croteau DL, Wilson DM III, Sobol RW, Yasui A and Bohr VA.
- Journal Title
  
  Mol Cell Biol.
  
  Volume: on line Issue: 16
- DOI
  10.1128/mcb.00237-17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H01737
[Journal Article] Collaboration of MLLT1/ENL, Polycomb and ATM for transcription and genome integrity2016
- Author(s)
  Ui A and Yasui A
- Journal Title
  
  Nucleus
  
  Volume: 7 Issue: 2 Pages: 138-145
- DOI
  10.1080/19491034.2016.1177681
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H01737, KAKENHI-PROJECT-26740016
[Journal Article] Unique food-entrained circadian rhythm in Cysteine414-Alanine mutant mCRY1 transgenic mice2016
- Author(s)
  Okano S, Yasui A, Hayasaka K, Nakajima O
- Journal Title
  
  Sleep and Biological Rhythms
  
  Volume: 印刷中 Issue: 3 Pages: 261-269
- DOI
  10.1007/s41105-016-0050-1
- NAID
  40020888020
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K08417
[Journal Article] Transcriptional elongation factor ENL phosphorylated by ATM recruits Polycomb and switches off transcription for DSB repair2015
- Author(s)
  Ui A, Nagaura Y, Yasui A
- Journal Title
  
  Mol Cell
  
  Volume: 58
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-22131005
[Journal Article] Transcriptional elongation factor ENL phosphorylated by ATM recruits polycomb and switches off transcription for DSB repair2015
- Author(s)
  Ui A, Nagaura Y, Yasui A
- Journal Title
  
  Molecular Cell
  
  Volume: ５８ Issue: 3 Pages: 468-482
- DOI
  10.1016/j.molcel.2015.03.023
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26740016, KAKENHI-PROJECT-15H01737
[Journal Article] Novel Methods for sire-specific induction of oxidative DNA damage reveals differences in recruitment of repair proteins to heterochromatin and euchromatin2014
- Author(s)
  Lan L, Nakajima S, Wei L, Sun L, Hsieh CL, Sobol RW, Bruchez M, van Houten B, Yasui A, and Levine AS
- Journal Title
  
  Nucleic Acids Res
  
  Volume: 196 Issue: 2 Pages: 443-453
- DOI
  10.1534/genetics.113.159541
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24310037
[Journal Article] SWI/SNF factors required for cellular resistance to DNA damage include ARID1A and ARID1B and show interdependent protein stability2014
- Author(s)
  Watanabe R, Ui A, Kanno S-I, Ogiwara H, Nagase T, Kohno T, and Yasui A.
- Journal Title
  
  Cancer Res.
  
  Volume: 74 Issue: 9 Pages: 2465-2475
- DOI
  10.1158/0008-5472.can-13-3608
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22131005, KAKENHI-PLANNED-22131006, KAKENHI-PROJECT-26340020, KAKENHI-PROJECT-26830122
[Journal Article] The BRCA1/BARD1-interacting protein OLA1 functions in centrosome regulation.2014
- Author(s)
  Matsuzawa A, Kanno S, Nakayama M, Mochiduki H, Wei L, Shimaoka T, Furukawa Y, Kato K, Shibata S, Yasui A, Ishioka C, Chiba N.
- Journal Title
  
  Mol Cell
  
  Volume: 53 Issue: 1 Pages: 101-114
- DOI
  10.1016/j.molcel.2013.10.028
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22131005, KAKENHI-PROJECT-23510059, KAKENHI-PROJECT-24300327, KAKENHI-PROJECT-24310037
[Journal Article] Novel method for site-specific induction of oxidative DNA damage reveals differences in recruitment of repair proteins to heterochromatin and euchromatin2014
- Author(s)
  Lan L, Nakajima S, Wei L, Sun L, Hsieh CL, Sobol RW, Bruchez M, Van Houten B, Yasui A, Levine AS.
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: 42 Issue: 4 Pages: 2330-45
- DOI
  10.1093/nar/gkt1233
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24310037
[Journal Article] Possible involvement of LKB1-AMPK signaling in non-homologous end joining.2014
- Author(s)
  Ui A, Ogiwara H, Nakajima S, Kanno S-I, Watanabe R, Harata M, Okayama H, Harris CC, Yokota J, Yasui A and Kohno T
- Journal Title
  
  Oncogene
  
  Volume: 33 Issue: 13 Pages: 1640-1648
- DOI
  10.1038/onc.2013.125
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-22131005, KAKENHI-PLANNED-22131006, KAKENHI-PROJECT-23510059, KAKENHI-PROJECT-23658281, KAKENHI-PROJECT-23701110, KAKENHI-PROJECT-24380183, KAKENHI-PROJECT-24710057, KAKENHI-PLANNED-25116009, KAKENHI-PUBLICLY-25118503, KAKENHI-PUBLICLY-25125703, KAKENHI-PROJECT-25660286, KAKENHI-PROJECT-26830122
[Journal Article] The nucleoporin Nup188 is required for chromosome alignment in mitosis2013
- Author(s)
  伊藤剛、杉野史朗、池田真教、水口万裕美、菅野新一郎、M.A.Amin、家村顕自、安井明、広田亨、田中耕三
- Journal Title
  
  Cancer Science
  
  Volume: (in press) Issue: 7 Pages: 871-879
- DOI
  10.1111/cas.12159
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12F02100, KAKENHI-PROJECT-23510059, KAKENHI-PROJECT-23651243, KAKENHI-PROJECT-23870001, KAKENHI-PUBLICLY-24114502, KAKENHI-PUBLICLY-24114517, KAKENHI-PROJECT-24370076, KAKENHI-PROJECT-24370078
[Journal Article] Damage response of XRCC1 at sites of DNA single strand breaks is regulated by phosphorylation and ubiquitination after degradation of poly (ADP) ribose.2013
- Author(s)
  Leizhen Wei,Satoshi Nakajima, Ching-Lung Hsieh, Shinichiro Kanno, Mitsuko Masutani, Arthur S. Levine1, Akira Yasui, Li Lan
- Journal Title
  
  J Cell Sci.
  
  Volume: 126(Pt 19) Issue: 19 Pages: 4414-23
- DOI
  10.1242/jcs.128272
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510059, KAKENHI-PROJECT-24310037
[Journal Article] Curcumin suppresses multiple DNA damage response pathways and has potency as a sensitizer to PARP inhibitor.2013
- Author(s)
  Ogiwara H, Ui A, Shiotani B, Zou L, Yasui A, Kohno T
- Journal Title
  
  Carcinogenesis
  
  Volume: 34 Issue: 11 Pages: 2486-2497
- DOI
  10.1093/carcin/bgt240
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22131006, KAKENHI-PROJECT-23701110, KAKENHI-PROJECT-24310037, KAKENHI-PROJECT-24710057, KAKENHI-PROJECT-25701005
[Journal Article] Polycomb group protein PHF1 regulates p53-dependent cell growth arrest and apoptosis.2013
- Author(s)
  Yang Y, Wang C, Zhang P, Gao K, Wang D, Yu H, Zhang T, Jiang S, Hexige S, Hong Z, Yasui A, Liu JO, Huang H, Yu L
- Journal Title
  
  J Biol Chem
  
  Volume: 288 Issue: 1 Pages: 529-539
- DOI
  10.1074/jbc.m111.338996
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24310037
[Journal Article] Alternative excision repair pathways.2013
- Author(s)
  Yasui A
- Journal Title
  
  Cold Spring Harb Perspect Biol.
  
  Volume: 8 Issue: 4 Pages: e60208-e60208
- DOI
  10.1371/journal.pone.0060208
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24310037
[Journal Article] Alternative excision repair pathways.2013
- Author(s)
  Yasui A.
- Journal Title
  
  Cold Spring Harb Perspect Biol.
  
  Volume: 5 Pages: 121-128
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22131005
[Journal Article] Alternative excision repair pathways2013
- Author(s)
  Yasui A.
- Journal Title
  
  Cold Spring Harb. Perspect. Biol.
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24310037
[Journal Article] CAMP(C13orf8, ZNF828)is a novel regulator of kinetochore-microtubule attachment2011
- Author(s)
  toh, G, Kanno, S, Uchida, K, S, K, Chiba, S, Sugino, S, Watanabe, K, Mizuno, K, Yasui, A, Hirota, T, and Tanaka, K
- Journal Title
  
  EMBO J
  
  Volume: 30 Pages: 130-144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570193
[Journal Article] The hMsh2-hMsh6 complex acts in concert with monoubiquitinated PCNA and Poll η in response to oxidative DNA damage in human cells2011
- Author(s)
  Zlatanou A, Despras E, Braz-Petta T, Boubakour-Azzouz I, Pouvelle C, Stewart GS, Nakajima S, Yasui A, Ishchenko AA, Kannouche PL
- Journal Title
  
  Mol Cell
  
  Volume: 43(4) Pages: 649-62
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20241011
[Journal Article] CAMP (C13orf8, ZNF828)is a novel regulator of kinetochore-microtubule attachment2011
- Author(s)
  Itoh G, Kanno SI, Uchida KS, Chiba S, Sugino S, Watanabe K, Mizuno K, Yasui A, Hirota T, and Tanaka K
- Journal Title
  
  EMBO J
  
  Volume: 30 Pages: 130-144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20241011
[Journal Article] Histone acetylation by p300 at double-strand break sites facilitates SWI/SNF chromatin remodeling and the recruitment of non-homologous end joining factors2011
- Author(s)
  Ogiwara H, Ui A, Otsuka A, Satoh H, Ymi I, Nakajima S, Yasui A, , Yokota J, and Kohno T
- Journal Title
  
  Oncogene
  
  Volume: 18 Pages: 2135-2146
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20241011
[Journal Article] PALF acts as both a single-stranded DNA end nuclease and a single-stranded DNA 3'-exonuclease and can participate in DNA end joining in a biochemical system2011
- Author(s)
  Li S, Kanno SI, Watanabe R, Ogiwara H, Kohno T, Watanabe G, Yasui A, and Lieber MR.
- Journal Title
  
  J Biol Chem
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20241011
[Journal Article] Mutant Cockayne syndrome group B protein inhibits repair of DNA topoisomerase I-DNA covalent complex2011
- Author(s)
  Horibata K, Saijo M, Bay MN, Lan L, Kuraoka I, Brook PJ, Honma M, Nohmi T, Yasui A., and Tanaka K
- Journal Title
  
  Genes Cells
  
  Volume: 16 Pages: 101-114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20241011
[Journal Article] DNA polymerase beta-dependent long patch base excision repair in living cells2010
- Author(s)
  Asagoshi K, Liu Y, Masaoka A, Lan L, Prasad R, Horton JK, Brown AR, Wang XH, Bdour HM, Sobol RW, Taylor JS, Yasui A, and Wilson SH
- Journal Title
  
  DNA Repair
  
  Volume: 9 Pages: 109-119
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20241011
[Journal Article] The ACF1 complex is required for DNA double-strand break repair in human cells2010
- Author(s)
  Lan L, Ui A, Nakajima S, Hatakeyama K, Hoshi M, Watanabe R, Janicki S, Ogiwara H, Kohno T, Kanno SI, and Yasui A
- Journal Title
  
  Mol Cell
  
  Volume: 40 Pages: 976-987
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20241011
[Journal Article] Solution structure of a zinc-finger domain that binds to poly-ADP-ribose2010
- Author(s)
  Isogai S, Kanno SI, Ariyoshi M, Tochio H, Ito Y, Yasui A, and Shirakawa M
- Journal Title
  
  Genes Cells
  
  Volume: 15 Pages: 101-110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20241011
[Journal Article] DNA polymerase zeta cooperates with polymerases kappa and iota in translesion DNA synthesis across pyrimidine photodimers in cells from XPV patients2009
- Author(s)
  Ziv O, Geacintov N, Nakajima S, Yasui A, and Livneh Z
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 106 Pages: 11552-11557
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20241011
[Journal Article] DNA polymerase zeta cooperates with polymerases kappa and iota in translesion DNA synthesis across pyrimidine photodimers in cells from XPV patients.2009
- Author(s)
  Ziv O, Geacintov, N.Nakajima, S, Yasui, A.Livneh, Z.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 106
  
  Pages: 11552-11557
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20241011
[Journal Article] Deficiency of the oxidative damage-specific DNA glycosylase NEIL1 leads to reduced germinal center B cell expansion2009
- Author(s)
  Mori H, Ouchida R, Hijikata A, Kitamura H, Ohara O, Li Y, Gao X, Yasui A, Lloyd RS, and Wang JY
- Journal Title
  
  DNA Repair (Amst)
  
  Volume: 8 Pages: 1328-1332
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20241011
[Journal Article] Human DNA polymerase iota protects cells against oxidative stress2008
- Author(s)
  Petta TB, Nakajima S, Zlatanou A, Despras E, Sarasin A, Yasui A, and Kannouche P
- Journal Title
  
  EMBO J
  
  Volume: 27 Pages: 2883-2895
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20241011
[Journal Article] Rapid recruitment of BRCA1 to DNA double-strand breaks is dependent on its association with Ku802008
- Author(s)
  Wei L, Lan L, Hong Z, Yasui A, Ishioka C, and Chiba N
- Journal Title
  
  Mol Cell Biol
  
  Volume: 28 Pages: 7380-7393
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20241011
[Journal Article] A polycomb group protein, PHF1, is involved in the response to DNA double-strand breaks in human cell2008
- Author(s)
  Hong Z, Jiang J, Lan L, Nakajima S, Kanno S, Koseki H, and Yasui A
- Journal Title
  
  Nucleic Acids Res
  
  Volume: 36 Pages: 2937-2947
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20241011
[Journal Article] Recruitment of mismatch repair proteins to the site of DNA damage in human cells2008
- Author(s)
  Hong Z, Jiang J, Hashiguchi K, Hoshi M, Lan L, and Yasui A
- Journal Title
  
  J. Cell Sci
  
  Volume: 121 Pages: 3146-3154
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20241011
[Journal Article] Regulation of proliferating cell nuclear antigen ubiquitination in mammalian cells2008
- Author(s)
  Niimi A, Brown S, Sabbioneda S, Kannouche P, Scott, A, Yasui A, Green CM, and Lehmann AR
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 105 Pages: 16125-16130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20241011
[Journal Article] HMGB1 is a co-factor in mammalian base excision repair2007
- Author(s)
  Prasad, R., Kanno, S., Yasui, A.
- Journal Title
  
  Mol Cell 27
  
  Pages: 829-841
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18012003
[Journal Article] A novel human AP endonuclease with conserved zinc-finger-like motifs involved in DNA strand break responses2007
- Author(s)
  Kanno, S. Yasui, A., 他
- Journal Title
  
  EMBO J. 26
  
  Pages: 2094-2103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16201010
[Journal Article] A novel human AP endonuclease with conserved zinc-finger-like motifs involved in DNA strand break responses2007
- Author(s)
  Kanno, S. Yasui, A., 他
- Journal Title
  
  EMBO J. 26
  
  Pages: 2094-2103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18012003
[Journal Article] The Werner syndrome protein interacts functionally with translesion DNA synthesis.2007
- Author(s)
  Kamath-Loeb, A. S., Yasui, A., 他
- Journal Title
  
  Proc. Natl. Acad. Sci. USA 104
  
  Pages: 10394-10399
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16201010
[Journal Article] HMGB1 is a co-factor in mammalian base excision repair2007
- Author(s)
  Prasad, R., Kanno, S, , Yasui, A.
- Journal Title
  
  Mol Cell 27
  
  Pages: 829-841
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16201010
[Journal Article] Recruitment of DNA repair synthesis machinery to sites of DNA damage/repair in living cells.2007
- Author(s)
  Hashiguchi, K., Matsumoto, Y., and Yasui, A.
- Journal Title
  
  Nucleic Acids Res. 35
  
  Pages: 2913-2923
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18012003
[Journal Article] MSH2-MSH6 stimulates DNA polymerase eta, suggesting a role for A-T mutation in immunoglobulin genes2005
- Author(s)
  Wilson TM, Vaisman A, Maritomo SA, Sullivan P, Lan L, Hanaoka F, Yasui A, Woodgate R, _Gearhart PJ.
- Journal Title
  
  J.Exp.Med. 201
  
  Pages: 637-645
- Data Source
  KAKENHI-PROJECT-16201010
[Journal Article] Translocation of XRCC1 and DNA ligase IIIa from centrosomes to chromosomes in response to DNA damage in mitotic human cells.2005
- Author(s)
  Okano S, Lan L, Tomkinson AE, Yasui A
- Journal Title
  
  Nucleic Acids Res. 33
  
  Pages: 422-429
- Data Source
  KAKENHI-PROJECT-16201010
[Journal Article] DNA repair initiated by glycosylases in the nucleus and mitochondria of mammalian cells ; how our cells respond to a flood of oxidative DNA damage2005
- Author(s)
  Takao M, Yasui A.
- Journal Title
  
  J Darmat Sci.Suppl. 1
- NAID
  10020568049
- Data Source
  KAKENHI-PROJECT-16201010
[Journal Article] Powerful skin cancer protection by a CPD-photolyase transgene2005
- Author(s)
  Jans J, Schul W, Sert Y-G, Rijksen Y, Rebel H, Eker APM, Nakajima S, van Steeg H, de Gruiji FR, Yasui A, Hoejimakers JHJ, van der Horst GTJ
- Journal Title
  
  Curr. Biology 15
  
  Pages: 1-20
- Data Source
  KAKENHI-PROJECT-16201010
[Journal Article] Accumulation of Werner protein at DNA double-strand breaks in human cells2005
- Author(s)
  Lan L., Nakajima S, Komatsu K, Nussenzweig A, Shimamoto A, Oshima J, Yasui A.
- Journal Title
  
  J. Cell Sci. 118
  
  Pages: 4153-4162
- Data Source
  KAKENHI-PROJECT-16201010
[Journal Article] DNA Polymerase lambda protect mouse fibroblasts against oxidative DNA damage and is recruited to sites of DNA damage repair2005
- Author(s)
  Braithwaite EK, Kedar PS, Lan L, Polosina YY, Asagoshi K, Poltorasky V, Horton JK, Miller H, Teebor GW, Yasui A, Wilson SH.
- Journal Title
  
  J.Biol.Chem. 280
  
  Pages: 31641-31647
- Data Source
  KAKENHI-PROJECT-16201010
[Journal Article] UV Light-induced DNA Damage and Tolerance for the Survival of Nucleotide Excision Repair-deficient Human Cells2004
- Author(s)
  Satoshi Nakajima., Li Lan, Shin-ichiro Kannno, Masashi Takano, Kazuo Yamamoto, Andre P.M.Eker., Akira Yasui
- Journal Title
  
  The Journal of Biological Chemistry 279
  
  Pages: 46674-46677
- Data Source
  KAKENHI-PROJECT-12143101
[Journal Article] In situ analysis of repair processes for oxidative DNA damage in mammalian cells.2004
- Author(s)
  Lan., L., Nakajima., S., Oohata, Y., Takao., M., Okano, S., Masutani., M., Wilson., S.H., Yasui, A.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 101
  
  Pages: 13738-13743
- Data Source
  KAKENHI-PROJECT-12143101
[Journal Article] Spatial and temporal assembly of the proteins involved in repair of single-strand breaks in Human cells.2003
- Author(s)
  Okano S, Lan L, Caldecot K, Mori T, Yasui A.
- Journal Title
  
  Mol.Cell.Biol. 23
  
  Pages: 3974-3981
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13480162
[Journal Article] Identification of 5-formyluracil DNA glycosylase activity of human hNTH1 protein.2002
- Author(s)
  Miiyabe I., Zhang QM., Kino K., Sugiyama H., Takao M., Yasui A., Yonei S.
- Journal Title
  
  Nucleic Acids Res. 30
  
  Pages: 3454-3463
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13480162
[Journal Article] A back-up glycosylase in Nth1-knockout mice is a functional Nei (endonuclease VIII) homologue.2002
- Author(s)
  Takao M, Kanno S, Kobayashi K, Zhang Q-M, Yonei S, van der Horst G, Yasui A.
- Journal Title
  
  J.Biol.Chem. 277
  
  Pages: 42205-42213
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13480162
[Journal Article] Photorepair of RNA polymerase arrest and apoptosis after ultraviolet irradiation in normal and XPB deficient rodent cells.2002
- Author(s)
  Chigancas V, Batista LF, Brumatti G, Amarante-Mendes GP, Yasui A, Menck CF
- Journal Title
  
  Cell Death Differ 9
  
  Pages: 1099-1107
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13480162
[Journal Article] A Novel nuclear and mitochondrial glycosylases revealed by disruption of the mouse Nth1 gene encoding an endonuclease III : homologue for repair of thymine glycol.2002
- Author(s)
  Takao M, Kanno S, Shiromoto T, Hasegawa R, Ide H, Iikeda S, Sarker AH, Seki S, Xing JZ, Le XC, Weinfeld M, Kobayashi K, Miyazaki J, Muijtjens M, Hoeijmakers JHJ, van der Horst G, Yasui.
- Journal Title
  
  EMBO J. 21
  
  Pages: 3486-3493
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13480162
[Patent] UVDE発現による相同組換え頻度向上2009
- Inventor(s)
  安井明
- Industrial Property Rights Holder
  安井明
- Filing Date
  2009-05-22
- Data Source
  KAKENHI-PROJECT-20241011
[Presentation] 時計蛋白質CRY1のC414A変異体過剰発現マウスにおける膵島内膵管生成の分子機序の解析2021
- Author(s)
  岡野聡, 安井明, 菅野新一郎, 佐藤賢一, 五十嵐雅彦, 中島修
- Organizer
  第51回日本膵臓学会大会
- Data Source
  KAKENHI-PROJECT-19K07498
[Presentation] Characteristic distribution of GRP78 in islets and intra-islet ductal cells of diabetic C414A-CRY1 transgenic mice2021
- Author(s)
  岡野聡, 安井明, 菅野新一郎, 佐藤賢一, 五十嵐雅彦, 中島修
- Organizer
  第81回米国糖尿病学会 (81th ADA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07498
[Presentation] Atypical trefoil factor family 2 expressing β-cells of diabetic mutant CRY1 transgenic mice with intraislet ducts2020
- Author(s)
  岡野聡, 安井明, 菅野新一郎, 佐藤賢一, 五十嵐雅彦, 中島修
- Organizer
  第80回米国糖尿病学会（80th Scientific Sessions American Diabetes Association )
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07498
[Presentation] 膵β細胞における亜鉛の動態変化が引き起こすストレスに対する転写因子MTF1とRGS タンパク質の応答2020
- Author(s)
  岡野聡, 安井明, 菅野新一郎, 佐藤賢一, 五十嵐雅彦, 中島修
- Organizer
  43回日本分子生物学会・MBSJ2020
- Data Source
  KAKENHI-PROJECT-19K07498
[Presentation] Altered expression of karyopherin α2 and circadian clock genes in MIN6 cells mimicking hyperglycemia2019
- Author(s)
  岡野聡, 安井明, 菅野新一郎, 佐藤賢一, 五十嵐雅彦, 中島修
- Organizer
  International Diabetes Federation (IDF) Congress 2019 in Busan
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07498
[Presentation] Characteristic features in the intraislet ductal cells of diabetic C414A-CRY1 transgenic mice2019
- Author(s)
  岡野聡, 安井明, 菅野新一郎, 佐藤賢一, 五十嵐雅彦, 中島修
- Organizer
  79th Scientific Sessions American Diabetes Association (ADA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07498
[Presentation] Frequent defect in nucleosome remodeling complexes reduces DNA repair2017
- Author(s)
  Akira Yasui
- Organizer
  33rd International Symposium of Radiation Biology Center, Kyoto University
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H01737
[Presentation] Chromatin remodeling, DNA repair and transcriptional regulation in cancer and aging2017
- Author(s)
  Akira Yasui
- Organizer
  International Symposium on Aging Biology, Tohoku Forum for Creativity
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H01737
[Presentation] Pancreatic intraepithelial neoplasia-like cells in diabetic cysteine414-alanine-mCRY1 transgenic mice2017
- Author(s)
  岡野聡, 安井明, 菅野新一郎, 佐藤賢一, 早坂清, 五十嵐雅彦, 中島修
- Organizer
  Tohoku Forum on Aging Science (IDAC, Tohoku University)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08417
[Presentation] Features of pancreatic intraepithelial neoplasia and tubular complex in diabetic cysteine414-alanine-mCRY1 transgenic mice2017
- Author(s)
  岡野聡, 安井明, 菅野新一郎, 佐藤賢一, 早坂清, 五十嵐雅彦, 中島修
- Organizer
  XV European Biological Rhythms Society Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08417
[Presentation] mCRY1-C414A変異体過剰発現マウスの膵臓におけるtubular complexからの膵β細胞の新生とKPNA2の発現2017
- Author(s)
  岡野聡, 安井明, 菅野新一郎, 佐藤賢一, 早坂清, 五十嵐雅彦, 中島修
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-15K08417
[Presentation] Reduced expression of KPNA2 and dysfunction of β-cells in C414A-CRY1 transgenic mice2017
- Author(s)
  岡野聡, 安井明, 菅野新一郎, 早坂清, 五十嵐雅彦, 中島修
- Organizer
  77th Scientific Sessions American Diabetes Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08417
[Presentation] Influence of chromatin remodeling on DNA repair, cancer and aging2017
- Author(s)
  Akira Yasui
- Organizer
  染色体ワークショップ
- Place of Presentation
  かずさアカデミアホール（千葉県・木更津市）
- Year and Date
  2017-01-16
- Data Source
  KAKENHI-PROJECT-15H01737
[Presentation] DNA repair within cell in chromatin context2017
- Author(s)
  Akira Yasui
- Organizer
  6th US-Japan DNA Repair Meeting at Berkeley, CA, USA
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H01737
[Presentation] Histone modification and nucleosome remodeling regulating transcription and DNA repair2017
- Author(s)
  Akira Yasui
- Organizer
  Conference of European Association of Cancer Research, Protecting the Code, Berlin
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H01737
[Presentation] システイン414-アラニン変異型CRY1過剰発現マウス膵島の導管様細胞2016
- Author(s)
  岡野聡, 安井明, 早坂清, 五十嵐雅彦, 中島修
- Organizer
  第59回日本糖尿病学会年次学術集会
- Place of Presentation
  国立京都国際会館 (京都府京都市)
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-15K08417
[Presentation] Chromatin remodeling for DNA double-strand break repair and transcriptional repression2016
- Author(s)
  Akira Yasui
- Organizer
  Cold Spring Harbor Asia Conference
- Place of Presentation
  Suzhou, China
- Year and Date
  2016-06-13
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H01737
[Presentation] Anomalous ductal structure in the islet of diabetic cysteine414-alanine-mCRY1 transgenic mice2016
- Author(s)
  岡野聡, 安井明, 菅野新一郎, 早坂清, 五十嵐雅彦, 中島修
- Organizer
  76th Scientific Sessions American Diabetes Association (ADA)
- Place of Presentation
  Ernest N. Morial Convention Center (ルイジアナ州ニューオーリンズ)
- Year and Date
  2016-06-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08417
[Presentation] Anomalous islet structure in diabetic cysteine414-alanine-mCRY1 transgenic mice2016
- Author(s)
  岡野聡, 安井明, 菅野新一郎, 早坂清, 五十嵐雅彦, 中島修
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター (宮城県仙台市)
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-15K08417
[Presentation] C414A変異mCRY1トランスジェニックマウスの膵島の異常と導管構造2016
- Author(s)
  岡野聡, 安井明, 菅野新一郎, 早坂清, 五十嵐雅彦, 中島修
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜 (神奈川県横浜市)
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K08417
[Presentation] Food-entrainable circadian rhythm and pathophisiology in Cys414-Ala mCRY1 transgenic mice2015
- Author(s)
  岡野聡, 安井明, 早坂清, 五十嵐雅彦, 中島修
- Organizer
  第15回ヨーロッパ時間生物学会(EBRS)・第4回世界時間生物学会連合大会(WCC)
- Place of Presentation
  マンチェスター大学 (イギリス)
- Year and Date
  2015-08-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08417
[Presentation] Unusual ductal structure in the islet of diabetic cysteine414-alanine mutant mCRY1 transgenic mice2015
- Author(s)
  岡野聡, 安井明, 早坂清, 五十嵐雅彦, 中島修
- Organizer
  キーストンシンポジア (糖尿病: 新しい分子メカニズムと治療戦略)
- Place of Presentation
  ウエスティン都ホテル京都 (京都府京都市)
- Year and Date
  2015-10-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08417
[Presentation] Chromatin remodeling and DNA repair2015
- Author(s)
  Akira Yasui
- Organizer
  Nuclear organization for genome stability
- Place of Presentation
  Osaka, Institutr for Protein Research, Osaka University
- Year and Date
  2015-05-18
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H01737
[Presentation] Senescence-like phenotype in pancreatic β-cells in diabetic mutant cryptochrome1 transgenic mice2015
- Author(s)
  岡野聡, 安井明, 早坂清, 五十嵐雅彦, 中島修
- Organizer
  第75回米国糖尿病学会（ADA）
- Place of Presentation
  Boston Convention and Exhibition Center (アメリカ)
- Year and Date
  2015-06-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08417
[Presentation] Regulation of Rgs4 in the islet of mutant cryptochrome1 transgenic mice2014
- Author(s)
  岡野聡, 安井明, 早坂清, 五十嵐雅彦, 中島修
- Organizer
  Homeodynamics in Clocks, Sleep and Metabolism Tokyo Translational Therapeutics Meeting
- Place of Presentation
  東京大学伊藤謝恩ホール(東京都)
- Year and Date
  2014-09-24
- Data Source
  KAKENHI-PROJECT-24590473
[Presentation] 糖尿病を示す変異型CRY1過剰発現マウス膵島の遺伝子発現及びCRY1 結合タンパク質の解析2014
- Author(s)
  岡野聡, 安井明, 早坂清, 五十嵐雅彦, 富樫義之, 中島修
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  リーガロイヤルホテル(大阪府)
- Year and Date
  2014-05-22
- Data Source
  KAKENHI-PROJECT-24590473
[Presentation] 糖尿病を示す変異型CRY1過剰発現マウス膵島の遺伝子発現及びCRY1結合蛋白質の解析2014
- Author(s)
  岡野聡, 安井明, 早坂清, 五十嵐雅彦, 富樫義之, 中島修
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  リーガロイヤルホテル(大阪府)
- Data Source
  KAKENHI-PROJECT-24590473
[Presentation] 時計タンパク質CRY1の変異体過剰発現マウスの膵β細胞の老化様変化と脱分化2014
- Author(s)
  岡野聡, 安井明, 早坂清, 五十嵐雅彦, 中島修
- Organizer
  第37回日本分子生物学会学術大会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2014-11-26
- Data Source
  KAKENHI-PROJECT-24590473
[Presentation] 時計タンパク質CRY1 の変異体過剰発現マウスにおける膵β細胞の機能不全2014
- Author(s)
  岡野聡, 安井明, 早坂清, 五十嵐雅彦, 中島修
- Organizer
  第26回分子糖尿病学シンポジウム
- Place of Presentation
  高知市文化プラザかるぽーと(高知県)
- Year and Date
  2014-12-06
- Data Source
  KAKENHI-PROJECT-24590473
[Presentation] 規分子CAMPのキネトコア-微小管結合に関する機能2012
- Author(s)
  伊藤剛, 菅野新一郎, 内田和彦, 千葉秀平, 水野健作, 安井明, 広田亨, 田中耕三
- Organizer
  第29回染色体ワークショップ
- Place of Presentation
  仙台
- Year and Date
  2012-01-25
- Data Source
  KAKENHI-PROJECT-21570193
[Presentation] DNA single-strand breaks and activation of PARP2012
- Author(s)
  安井　明
- Organizer
  US-Japan DNA Repair Meeting
- Place of Presentation
  ワシントン (DC) 米国
- Year and Date
  2012-04-15
- Invited
- Data Source
  KAKENHI-PLANNED-22131005
[Presentation] Single-strand breaks and PARP activation2012
- Author(s)
  安井明
- Organizer
  第4回日米DNA修復会議
- Place of Presentation
  ワシントンDC, 米国(招待講演)
- Data Source
  KAKENHI-PROJECT-24310037
[Presentation] Chromatin remodeling and DNA double-strand break repair2012
- Author(s)
  安井　明
- Organizer
  The 3rd Erling Seeberg Symposium
- Place of Presentation
  トロンハイム／ノルウエイ
- Year and Date
  2012-06-19
- Invited
- Data Source
  KAKENHI-PLANNED-22131005
[Presentation] 新規分子CAMP(C13orf8, ZNF828)によるキネトコア-微小管結合の制御2011
- Author(s)
  伊藤剛, 菅野新一郎, 内田和彦, 千葉秀平, 水野健作, 安井明, 広田亨, 田中耕三
- Organizer
  第28回染色体ワークショップ
- Place of Presentation
  加賀
- Year and Date
  2011-01-11
- Data Source
  KAKENHI-PROJECT-21570193
[Presentation] クロマチンリモデリングの可視化プロテオミクス2011
- Author(s)
  Akira Yasui
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PLANNED-22131005
[Presentation] Function of CAMP(C13orf8, ZNF828)in kinetochore-microtubule attachment2011
- Author(s)
  伊藤剛, 菅野新一郎, 内田和彦, 千葉秀平, 水野健作, 安井明, 広田亨, 田中耕三
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PROJECT-21570193
[Presentation] Roles of chromatin remodeling factors in DNA double-strand break repair in human cell2010
- Author(s)
  Yasui A
- Organizer
  The 7^<th> 3R Symposium
- Place of Presentation
  Toyama Conference Center, Toyama, Japan
- Data Source
  KAKENHI-PROJECT-20241011
[Presentation] MAD2L2と結合する新規分子C13orf8によるキネトコア-微小管結合の制御2010
- Author(s)
  伊藤剛, 菅野新一郎, 安井明, 広田亨, 田中耕三
- Organizer
  第27回染色体ワークショップ
- Place of Presentation
  御殿場
- Year and Date
  2010-01-20
- Data Source
  KAKENHI-PROJECT-21570193
[Presentation] 新規MAD2L2結合分子CAMP(C13orf8, ZNF828)によるキネトコア-微小管結合の制御2010
- Author(s)
  伊藤剛, 菅野新一郎, 内田和彦, 千葉秀平, 水野健作, 安井明, 広田亨, 田中耕三
- Organizer
  第9回核ダイナミクス研究会
- Place of Presentation
  伊豆
- Year and Date
  2010-05-28
- Data Source
  KAKENHI-PROJECT-21570193
[Presentation] CAMP(C13orf8, ZNF828)is a novel regulator of kinetochore-microtubule attachment2010
- Author(s)
  伊藤剛, 菅野新一郎, 内田和彦, 千葉秀平, 水野健作, 安井明, 広田亨, 田中耕三
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-10-22
- Data Source
  KAKENHI-PROJECT-21570193
[Presentation] A novel MAD2L2-interacting protein, CAMP, is a regulator of kinetochore-microtubule attachment2010
- Author(s)
  田中耕三, 伊藤剛, 安井明, 広田亨
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21570193
[Presentation] Spatio-temporal organization of DNA single-strand break repair by PARP, PARG and XRCC1 in human cell2009
- Author(s)
  Lan L, Nakajima S, Hong S, Kanno SI, and Yasui A.
- Organizer
  DNA Repair and Mutagenesis, ASM Conference
- Place of Presentation
  Whistler, BC, Canada
- Data Source
  KAKENHI-PROJECT-20241011
[Presentation] Repair of DNA strand breaks in living human cells and implications for cancer therapy2009
- Author(s)
  Yasui A, Lan L, Nakajima S, Hatakeyama K, Zehui H, and Kanno SI
- Organizer
  40^<th> International Symposium of the Princess Takamatsu Cancer Research Fund
- Place of Presentation
  Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-20241011
[Presentation] Repair of DNA Strand Breaks in Living Human Cell and Its Implication for Cancer Therapy2009
- Author(s)
  安井明
- Organizer
  第40回高松宮妃記念国際癌研究シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20241011
[Presentation] Mismatch repair proteins at DNA single-and double-strand breaks and UV-lesions2009
- Author(s)
  Hong Z, and Yasui A.
- Organizer
  US-EU Conference on Repair of Endogeneous Genome Damage
- Place of Presentation
  Galveston, Texas, USA
- Data Source
  KAKENHI-PROJECT-20241011
[Presentation] 新規MAD2結合分子MAD2BP1によるキネトコア-微小管結合の制御2009
- Author(s)
  伊藤剛, 菅野新一郎, 安井明, 広田亨, 田中耕三
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-21570193
[Presentation] Novel AP endonuclease with 3'-5' exonuclease and single-strand break repair activities in human cell2008
- Author(s)
  Kanno SI, Sasao S, Kuzuoka H, Suzuki C, Lan L, Nakajima S, and Yasui A.
- Organizer
  6^<th> 3R Symposium
- Place of Presentation
  Awajishima Yumebutai, Japan
- Data Source
  KAKENHI-PROJECT-20241011
[Presentation] Novel AP endonucleases with exonuclease activity and DNA strand break repair in human cell2008
- Author(s)
  安井明
- Organizer
  10^<th> International Workshop on Radiation Damage to DNA
- Place of Presentation
  福島県、裏磐梯ロイヤルホテル
- Year and Date
  2008-06-10
- Data Source
  KAKENHI-PROJECT-20241011
[Presentation] Novel AP endonuclease with exonuclease activity and DNA strand break repair in human cell2008
- Author(s)
  Kanno SI, Lan L, Nakajima S, and Yasui A
- Organizer
  10^<th> International Workshop on Radiation Damage to DNA
- Place of Presentation
  Urabandai, Fukushima, Japan
- Data Source
  KAKENHI-PROJECT-20241011
[Presentation] DNA修復を組織するマッチメーカー蛋白の動態と修復プロセスの可視化解析2007
- Author(s)
  安井明
- Organizer
  第7回日本蛋白質科学会年会
- Place of Presentation
  仙台国際センター
- Year and Date
  2007-05-26
- Data Source
  KAKENHI-PROJECT-16201010
[Presentation] Cellular responses to DNA strand breaks in human cells2007
- Author(s)
  Yasui, A.
- Organizer
  Gordon Research Conference on Mammalian DNA Repair
- Place of Presentation
  Ventura, CA, USA.
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16201010
[Presentation] Cellular responses to single-strand breaks, a major cause of cancer between base damage and double-strand breaks2006
- Author(s)
  Yasui A.
- Organizer
  Gordon Research Conference on DNA damage, Mutation and Cancer
- Place of Presentation
  Ventura, CA, USA.
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16201010
[Presentation] Cellular responses to single-strand breaks, a major cause of cancer between base damage and double-strand breaks2006
- Author(s)
  Yasui, A.
- Organizer
  Gordon Research. Conference on DNA damage, Mutatiou and Cancer
- Place of Presentation
  Ventura, CA, USA.
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16201010
[Presentation] Dynamic responses to Single-strand Breaks in Human cells.2005
- Author(s)
  Yasui A.
- Organizer
  Keystone Symposia ; Genome Instability and Repair
- Place of Presentation
  Taos, New Mexico, USA.
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16201010
[Presentation] Following cellular responses induced by oxidative DNA damage in human cells.2005
- Author(s)
  Yasui, A.
- Organizer
  Gordon Research Conference on Genetic Toxicology
- Place of Presentation
  New London, NH, USA.
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16201010
[Presentation] Dynamic responses to Single-strand Breaks in Human cells2005
- Author(s)
  Yasui, A.
- Organizer
  Keystone Symposia ; Genome Instability and Repair
- Place of Presentation
  Taos, New Mexico, USA.
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16201010
[Presentation] 染色体分配における核膜複合体構成因子Nup188の機能
- Author(s)
  伊藤剛、安井明、広田亨、田中耕三
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24370078
[Presentation] Mitotic role of Nup188, a component of the nuclear pore complex
- Author(s)
  伊藤剛、池田真教、菅野新一郎、M.A.Amin、家村顕自、安井明、広田亨、田中耕三
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24370078
[Presentation] 染色体分配における核膜孔複合体構成因子Nup188の機能
- Author(s)
  伊藤剛、杉野史朗、池田真教、水口万裕美、菅野新一郎、M.A.Amin、家村顕自、安井明、広田亨、田中耕三
- Organizer
  日本生化学会東北支部第79回例会・シンポジウム
- Place of Presentation
  東北大学(仙台)
- Data Source
  KAKENHI-PROJECT-24370078
[Presentation] The nucleoporin Nup188 is required for chromosome alignment in mitosis
- Author(s)
  伊藤剛、杉野史朗、池田真教、水口万裕美、菅野新一郎、M.A.Amin、家村顕自、安井明、広田亨、田中耕三
- Organizer
  NIH-Tohoku University-JSPS Symposium
- Place of Presentation
  東北大学(仙台)
- Data Source
  KAKENHI-PROJECT-24370078
[Presentation] Repair and Chromatin Remodeling Factors Required for Cellular Resistance to Radiation Damage
- Author(s)
  Akira Yasui and Reiko Watanabe
- Organizer
  13th International Workshop on Radiation Damage to DNA
- Place of Presentation
  MIT USA
- Year and Date
  2014-06-14 – 2014-06-18
- Invited
- Data Source
  KAKENHI-PLANNED-22131005
[Presentation] 核膜孔複合体構成因子Nup188による染色体分配の制御について
- Author(s)
  伊藤剛、池田真教、菅野新一郎、M.A.Amin、家村顕自、安井明、広田亨、田中耕三
- Organizer
  第22回DNA複製・組換え・修復ワークショップ
- Place of Presentation
  秋保温泉ホテルニュー水戸屋(仙台)
- Data Source
  KAKENHI-PROJECT-24370078
[Presentation] SWI/SNF Chromatin-Remodeling Factors Required for both NHEJ and NER are Frequently Silenced in Cancer Cell
- Author(s)
  Reiko Watanabe, Shinichiro Kanno and Akira Yasui
- Organizer
  5th Japan-US/ US-Japan DNA Repair Meeting
- Place of Presentation
  徳島
- Year and Date
  2014-10-28 – 2014-10-31
- Invited
- Data Source
  KAKENHI-PLANNED-22131005

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Yasui Akira 安井 明

安井 明 ヤスイ アキラ

YASUI Akira 安井 明

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Functions of BAF complex in DNA repair and cancer therapyPrincipal Investigator

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Cellular response to DNA single-strand break and its repairPrincipal Investigator

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Visualization and proteomics of chromatin remodeling in DNA damage responsePrincipal Investigator

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Novel DNA damage responses and repair regulated by poly-ADP ribosylation and chromatin remodelingPrincipal Investigator

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ゲノム単鎖切断に関わるゲノム不安定性と細胞死Principal Investigator

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Yasui Akira 安井明

安井明ヤスイアキラ

YASUI Akira 安井明