YOKOI Masayuki 横井雅幸

Researcher Number	00322701
Other IDs
Affiliation (Current)	2022: 神戸大学, バイオシグナル総合研究センター, 准教授
Affiliation (based on the past Project Information) *help	2016 – 2020: 神戸大学, バイオシグナル総合研究センター, 准教授 2009 – 2015: 学習院大学, 理学部, 助教 2012: 学習院大学, 理学部生命科学科, 助教 2009: 大阪大学, 生命機能研究科, 助教 2007: 大阪大学, 大学院・生命機能研究科, 助教 … More
Review Section/Research Field	Principal Investigator Risk sciences of radiation and chemicals / Molecular biology / Cell biology / 環境影響評価(含放射線生物学) / Risk sciences of radiation/Chemicals / Basic Section 63020:Radiation influence-related Except Principal Investigator Biological Sciences / Biological pharmacy / Molecular biology / Biological pharmacy / Basic Section 63030:Chemical substance influence on environment-related
Keywords	Principal Investigator DNA損傷 / ヌクレオチド除去修復 / 分裂酵母 / 損傷乗り越え複製 / 紫外線 / 損傷乗り越え合成 / DNAポリメラーゼ / 突然変異 / クロマチン / 色素性乾皮症 … More Except Principal Investigator TFIIE / TFIIH / 基本転写因子 / 色素性乾皮症 / 損傷乗り越え複製 / DNAポリメラーゼ / 紫外線 / DNAポリメラーゼ・イータ / REV1 / RNAポリメラーゼII(Pol II) / 転写開始・伸長段階 / Znフィンガーモチーフ / ノックアウトマウス / ユビキチン / 突然変異 / ヌクレオチド除去修復 / 転写開始 / 転写伸長への移行 / Znフィンガー領域 / DNA修復 / 色素性乾皮症バリアント / 損傷トレランス / DNA損傷トレランス / 遺伝子ノックアウト / DNA損傷 / translesion synthesis / RNAポリメターゼII / NMR / XPC / 皮膚癌 / 遺伝病 / 細胞周期 / サイクリン依存性キナーゼ / メディエーター複合体 / がん / 遺伝子 / ゲノム安定性 / ミスマッチ修復 / タンパク質構造 / 癌 / ゲノム / 分裂酵母 / DNAポリメラーゼ・イオタ / 複製フォーク停止 / 損傷乗り越え合成 / PCNA / X線結晶構造解析 / DNAポリメラーゼη / スフィンゴシン / XPV / モデルマウス / シャトルベクター / 体細胞超突然変異 / WAモチーフ / ピリミジン二量体 / 紫外線損傷 / シスプラチン / 翻訳後修飾 / Hsp90 / モノユビキチン化PCNA / CPD / X線結晶構造 / DNAポリメラーゼ・ゼータ / ニワトリDT40 / TLSポリメラーゼ / DNAポリメラーゼκ / (6-4)光産物 / 紫外線感受性 / 発がん / polイータ / DNA複製 / 活性酸素 / XPVポリメラーゼ / XP variant / DNA polymerase / DNA lesions / knockout mice / carcinogenesis / XPCタンパク質 / HR23Bタンパク質 / チミンDNAグリコシラーゼ / Polη / Polι / SUMO-1 / DDB / 色素乾皮症 / APエンドヌクレアーゼ / SUMO-I / nucleotide excision repair / XPC protein / HR23B protein / xeroderma pigmentosum / thymine DNA glycosylase / DNA polymerase η / DNA polymerase τ / RNAポリメラーゼII / 転写メディエーター複合体 / 古細菌 / CTD / リン酸化 / RNA polymeraseII / Transcription Mediator Complex / General Transcription Factor / Archae bactria / Transcription Initiation Elongation / Zn Finger Motit / グリシドアミド / アクリルアミド / 遺伝毒性 / 変異原性 / 損傷乗り越えDNA合成 / 食品汚染物質 Less

ゲノム複製の停止と再開に関連したTLS機構とクロマチン構造変換のクロストークPrincipal Investigator
- Principal Investigator
  
  横井雅幸
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 63020:Radiation influence-related
- Research Institution
  Kobe University
Molecular mechanism of acrylamide-induced mutagenesis via translesion synthesis
- Principal Investigator
  
  赤木純一
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 63030:Chemical substance influence on environment-related
- Research Institution
  National Institute of Health Sciences
Studies on the molecular mechanisms to regulate the resumption of stalled replication by translesion synthesis at DNA damage sitesPrincipal Investigator
- Principal Investigator
  
  YOKOI MASAYUKI
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Kobe University
Functional analyses of translesion synthesis DNA polymerase Poleta based on its structural featuresPrincipal Investigator
- Principal Investigator
  
  YOKOI MASAYUKI
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Kobe University
  Gakushuin University
Generality of translesion synthesis coupling replication and repair
- Principal Investigator
  
  HANAOKA FUMIO
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Gakushuin University
Analyses of functional roles of TLS polymerases using transgenic mice
- Principal Investigator
  
  HANAOKA Fumio
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Gakushuin University
Physiological role of protein-protein interaction among translesion DNA polymerases in cellular resistance to ultraviolet lightPrincipal Investigator
- Principal Investigator
  
  YOKOI Masayuki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Gakushuin University
Molecular mechanisms of translesion DNA synthesis and its involvement in carcinogenesis
- Principal Investigator
  
  HANAOKA Fumio
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Gakushuin University
  Osaka University
転写因子の欠損に起因する発がんにおける基本転写因子の役割と核内シグナル伝達機構
- Principal Investigator
  
  大熊芳明
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
転写因子の欠損に起因する発がんにおける基本転写因子の役割と核内シグナル伝達機構
- Principal Investigator
  
  大熊芳明
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
複数のサイクリン依存性キナーゼ複合体によるRNAポリメラーゼIIの転写制御の解析
- Principal Investigator
  
  大熊芳明
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
DNA修復因子と中心体構成因子の遺伝的相互作用とその細胞生物学的意義Principal Investigator
- Principal Investigator
  
  横井雅幸
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Cell biology
- Research Institution
  Osaka University
分裂酵母のDNA修復と損傷乗り越え複製制御機構の分子遺伝学的解析Principal Investigator
- Principal Investigator
  
  横井雅幸
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  Osaka University
転写因子の欠損に起因する発がんにおける基本転写因子の役割と核内シグナル伝達機構
- Principal Investigator
  
  OHKUMA Yoshiaki
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
STUDY ON NOVEL REQULATORY MECHANISMA OF DNA REPAIR
- Principal Investigator
  
  HANAOKA Fumio
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Molecular biology
- Research Institution
  OSAKA UNIVERSITY
Biochemical and Ganetical Analyses of Organized Regularly Mechanism of Gene Expression by Various Transcription Super-Complex.
- Principal Investigator
  
  OHKUMA Yoshiaki
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Osaka university
真核生物のヌクレオチド除去修復の解析とモデル動物を用いた発癌機構の研究Principal Investigator
- Principal Investigator
  
  横井雅幸
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Molecular biology
- Research Institution
  Osaka University
Studies on Molecular Mechanisms of Translesion Synthesis and Carcinogenesis
- Principal Investigator
  
  HANAOKA Fumio
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University

All 2020 2019 2018 2017 2016 2015 2014 2012 2011 2010 2007 2006 2005 Other

All Journal Article Presentation

[Journal Article] Effect of sequence context on Polζ-dependent error-prone extension past (6-4) photoproducts2020
- Author(s)
  Akagi J,Hashimoto K,Suzuki K,Yokoi M,de Wind N,Iwai S,Ohmori H,Moriya M,Hanaoka F
- Journal Title
  
  DNA Repair
  
  Volume: 87 Pages: 102771-102771
- DOI
  10.1016/j.dnarep.2019.102771
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K12348
[Journal Article] Hypersensitivity of mouse embryonic fibroblast cells defective for DNA polymerases η, ι and κ to various genotoxic compounds: Its potential for application in chemical genotoxic screening2018
- Author(s)
  Akagi Jun-ichi、Yokoi Masayuki、Cho Young-Man、Toyoda Takeshi、Ohmori Haruo、Hanaoka Fumio、Ogawa Kumiko
- Journal Title
  
  DNA Repair
  
  Volume: 61 Pages: 76-85
- DOI
  10.1016/j.dnarep.2017.11.006
- NAID
  120006456929
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K00551, KAKENHI-PROJECT-16K16199, KAKENHI-PROJECT-15K14953, KAKENHI-PROJECT-15H04646
[Journal Article] Two mammalian homologs of yeast Rad23, HR23A and HR23B, as multifunctional proteins2017
- Author(s)
  Yokoi M, Hanaoka F
- Journal Title
  
  Gene
  
  Volume: 597 Pages: 1-9
- DOI
  10.1016/j.gene.2016.10.027
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04646, KAKENHI-PROJECT-26340028, KAKENHI-PROJECT-15K14953
[Journal Article] UV-induced mutagenesis in epidermal cells of mice defective in DNA polymerase η and/or ι2015
- Author(s)
  Kanao R, Yokoi M, Ohkumo T, Sakurai Y, Dotsu K, Kura S, Nakatsu Y, Tsuzuki T, Masutani C, Hanaoka F
- Journal Title
  
  DNA Repair (Amst)
  
  Volume: S1568-7864(15) Pages: 139-146
- DOI
  10.1016/j.dnarep.2015.02.006
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25241011, KAKENHI-PROJECT-26340028, KAKENHI-PROJECT-26740017, KAKENHI-PROJECT-26340025, KAKENHI-PROJECT-15K14953, KAKENHI-ORGANIZER-22131001, KAKENHI-PUBLICLY-15H00897, KAKENHI-PLANNED-24108009, KAKENHI-PROJECT-15H02654, KAKENHI-PROJECT-15H04646
[Journal Article] Remarkable induction of UV-signature mutations at the 3’-cytosine of dipyrimidine sites except at 5’-TCG-3’ in the UVB-induced skin epidermis of xeroderma pigmentosum variant model mice.2014
- Author(s)
  Ikehata H, Chang Y, Yokoi M, Yamamoto M, Hanaoka F
- Journal Title
  
  DNA Repair
  
  Volume: 22 Pages: 112-122
- DOI
  10.1016/j.dnarep.2014.07.012
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-22131008, KAKENHI-PROJECT-24310036, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-26340028
[Journal Article] Identification of new scavengers for hydroxyl radicals and superoxide dismutase by utilizing ultraviolet A photoreaction of 8-methoxypsoralen and a variety of mutants of Escherichia coli : implications on certain diseases of DNA repair deficiency2012
- Author(s)
  Ahmad, S., Yokoi, M., and Hanaoka, F
- Journal Title
  
  J. Photochem. Photobiol. B.
  
  Volume: 116 Pages: 30-36
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249005
[Journal Article] Stalled Polη at its cognate substrate initiates an alternative translesion synthesis pathway via interaction with REV12012
- Author(s)
  Ito, W*., Yokoi, M*., Sakayoshi, N., Sakurai, Y., Akagi, J., Mitani, H., and Hanaoka, F. (*: equal contribution)
- Journal Title
  
  Genes to Cells
  
  Volume: 17 Pages: 98-108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510063
[Journal Article] Identification of new scavengers for hydroxyl radicals and superoxide dismutase by utilizing ultraviolet A photoreaction of 8-methoxypsoralen and a variety of mutants of Escherichia coli: implications on certain diseases of DNA repair deficiency.2012
- Author(s)
  Ahmad, S.I., Yokoi, M., Hanaoka, F.
- Journal Title
  
  J. Photochem. Photobiol. B
  
  Volume: 116 Pages: 30-36
- DOI
  10.1016/j.jphotobiol.2012.07.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510063
[Journal Article] Stalled Polη at its cognate substrate initiates an alternative translesion synthesis pathway via interaction with REV12012
- Author(s)
  Ito W
- Journal Title
  
  Genes Cells
  
  Volume: 17 Pages: 98-108
- DOI
  10.1111/j.1365-2443.2011.01576.x
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22131001, KAKENHI-PLANNED-22131008, KAKENHI-PROJECT-22710059, KAKENHI-PROJECT-22249005
[Journal Article] Identification of new scavengers for hydroxyl radicals and superoxide dismutase by utilizing ultraviolet A photoreaction of 8-methoxypsoralen and a variety of mutants of Escherichia coli: implications on certain diseases of DNA repair deficiency2012
- Author(s)
  Ahmad, S.I., Yokoi, M., Hanaoka, F
- Journal Title
  
  J. Photochem. Photobiol. B
  
  Volume: 116 Pages: 30-36
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510063
[Journal Article] 立体構造から見えてきた損傷乗り越え DNA 複製の分子メカニズム2011
- Author(s)
  道津貫太郎、横井雅幸、花岡文雄
- Journal Title
  
  放射線生物研究
  
  Pages: 1-14
- Data Source
  KAKENHI-PROJECT-22510063
[Journal Article] 立体構造から見えてきた損傷乗り越えDNA複製の分子メカニズム2011
- Author(s)
  道津貫太郎、横井雅幸、花岡文雄
- Journal Title
  
  放射線生物研究
  
  Volume: 46 Pages: 1-14
- Data Source
  KAKENHI-PROJECT-22510063
[Journal Article] Ultraviolet B radiation induces epithelial tumors in mice lacking pol η and mesenchymal tumors in mice deficient for pol2006
- Author(s)
  Ohkumo, T., Kondo, Y., Yokoi, M., Tsukamoto, T., Yamada, A., Sugimoto, T., Kanao, R., Higashi, Y., Kondoh, H., Tatematsu, M., Masutani, C., Hanaoka, F.
- Journal Title
  
  ι.Mal.Cell.Biol. 26
  
  Pages: 7696-7706
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013053
[Journal Article] Different mutation signatures in DNA polymerase η- and MSH6-deficient mice suggest separate roles in antibody diversification.2005
- Author(s)
  Martomo, S.A., Yang, W.W., Wersto, R.P., Ohkumo, T., Kondo, Y., Yokoi, M., Masutani, C., Hanaoka, F., Gearhart, P.J.
- Journal Title
  
  Proc.Natl.Acad Sci.USA 102
  
  Pages: 8656-8661
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013053
[Journal Article] Different mutation signatures in DNA polymerase η-and MSH6-deficient mice suggest separate roles in antibody diversification.
- Author(s)
  Martomo, S.A., Yang, W.W., Wersto, R.P., Ohkumo, T., Kondo, Y., Yokoi, M., Masutani, C., Hanaoka, F., Gearhart, P.J.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12213070
[Presentation] The N7-glycidamide adduct of 2’-deoxyguanosine on the template strand induces DNA replication inhibition and mutagenesis in human cells2020
- Author(s)
  184.Jun-ichi Akagi, Masayuki Yokoi, Young-Man Cho, Shigenori Iwai, Fumio Hanaoka, Kaoru Sugasawa, Kumiko Ogawa
- Organizer
  第47回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-20K12163
[Presentation] アクリルアミドの活性代謝物であるグリシドアミドのデオキシグアノシンN7位付加体はDNA複製阻害と点突然変異を誘発する2020
- Author(s)
  赤木純一,横井雅幸,Young-Man Cho,岩井成憲,花岡文雄,菅澤薫,小川久美子
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-19K12348
[Presentation] 鋳型鎖上の2’-デオキシグアノシンN 7位グリシドアミド付加体はヒト細胞においてDNA複製を阻害し点突然変異を誘発する2020
- Author(s)
  赤木純一, 横井雅幸, 曺永晩, 岩井成憲, 花岡文雄, 菅澤薫, 小川久美子
- Organizer
  第47回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-19K12348
[Presentation] ヌクレオチド除去修復の損傷認識を制御するクロマチン構造変換因子の探索2019
- Author(s)
  草尾佳那子, 日下部将之, 各務恵理菜, 栗原文佳, 前田拓海, 横井雅幸, 酒井恒, 菅澤薫
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K00551
[Presentation] アクリルアミドの活性代謝物であるグリシルアミドのデオキシグアノシンN7位付加体はDNA複製阻害と点突然変異を誘発する2019
- Author(s)
  赤木純一, 横井雅幸, Young-Man Cho, 岩井成憲, 花岡文雄, 菅澤薫, 小川久美子
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-17K00551
[Presentation] XPCタンパク質によるDNA損傷認識の制御とヒストン修飾の役割2019
- Author(s)
  栗原文佳, 日下部将之, 各務恵理菜, 草尾佳那子, 前田拓海, 横井雅幸, 酒井恒, 菅澤薫
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K00551
[Presentation] N7-グリシドアミドdG付加体により誘発されるDNA複製阻害と変異原性の解析2019
- Author(s)
  赤木純一,横井雅幸,Young-Man Cho,岩井成憲,花岡文雄,菅澤薫,小川久美子
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K12348
[Presentation] RNAを介したヌクレオチド除去修復制御機構の解析2019
- Author(s)
  古川真理, 日下部将之, 酒井恒, 横井雅幸, 菅澤薫
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K00551
[Presentation] DNAポリメラーゼ・イータと脱ユビキチン化酵素の相互作用の解析2019
- Author(s)
  案済萌, 西村潤, 菅野新一郎, 安井明, 酒井恒, 菅澤薫, 花岡文雄, 横井雅幸
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K00551
[Presentation] ファンコニ貧血タンパク質FANCD2と脂質代謝関連因子の機能的連関の解析2019
- Author(s)
  大槻侑恵, 後藤元成, 乾愛実, 松田俊, 松田知成, 横井雅幸, 菅澤薫, 酒井恒
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K00551
[Presentation] ヌクレオチド除去修復におけるDNA損傷認識を制御するクロマチン構造動態2019
- Author(s)
  日下部将之, 栗原文佳, 草尾佳那子, 横井雅幸, 酒井　恒, 菅澤　薫
- Organizer
  第6回アジア環境変異学会・日本環境変異学会第48回大会　合同大会
- Data Source
  KAKENHI-PROJECT-17K00551
[Presentation] Dynamics of FANCD2 in response to lipid metabolism2019
- Author(s)
  Yukie Otsuki, Motonari Goto, Megumi Inui, Masayuki Yokoi, Kaoru Sugasawa, Wataru Sakai
- Organizer
  2019 Fanconi Anemia Scientific Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K00551
[Presentation] 脂質代謝に応答したファンコニ貧血タンパク質のダイナミクス2019
- Author(s)
  酒井恒, 乾愛実, 大槻侑恵, 後藤元成, 横井雅幸, 菅澤薫
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K00551
[Presentation] TLSポリメラーゼの損傷部位への導入過程を生細胞イメージングにより解析する試み2019
- Author(s)
  福永匠, 尾崎未羽, 佐藤正康, 酒井恒, 菅澤薫, 花岡文雄, 横井雅幸
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K00551
[Presentation] N7-グリシドアミドdG付加体により誘発されるDNA複製阻害と変異原性の解析2019
- Author(s)
  赤木純一, 横井雅幸, Young-Man Cho, 岩井成憲, 花岡文雄, 菅澤薫, 小川久美子
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K00551
[Presentation] Analysis of interaction between DNA polymerase η and deubiquitinating enzyme2018
- Author(s)
  案済萌、西村潤、菅野新一郎、安井明、菅澤薫、花岡文雄、横井雅幸
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K00551
[Presentation] Effect of Polκ deficiency on benzo[a]pyrene-induced tumorigenesis2018
- Author(s)
  Akagi, J., Cho, Y-M., Toyoda, T., Yokoi, M., Hanaoka, F., Ohmori, H., Ogawa, K.
- Organizer
  The 5th DNA polymerase meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K00551
[Presentation] Benzo[a]pyrene-induced tumorigenesis in Polκ-knockout mice2018
- Author(s)
  Akagi, J., Cho, Y-M., Toyoda, T., Yokoi, M., Hanaoka, F., Ohmori, H., Ogawa, K.
- Organizer
  The 11th 3R+3C Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K00551
[Presentation] N7-glycidamide-dG adduct inhibits DNA replication in mammalian cells2018
- Author(s)
  Akagi, J., Yokoi, M., Cho, Y-M., Yamamoto, J., Mizuta, Y., Iwai, S., Hanaoka, F., Ogawa, K.
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K00551
[Presentation] DNA損傷による複製の停止を回避する機構とその制御2018
- Author(s)
  横井雅幸
- Organizer
  神戸大学第６回バイオシグナル研究会
- Data Source
  KAKENHI-PROJECT-17K00551
[Presentation] Translesion synthesis-associated chromatin remodeling factors contribute the function of human DNA polymerase η in cisplatin-treated cells2018
- Author(s)
  Yokoi, M., Shikaya, Y., Sugasawa, K., Hanaoka, F.
- Organizer
  The 11th 3R+3C Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K00551
[Presentation] Analysis of contribution of Polκ to benzo[a]pyrene-induced tumorigenesis2018
- Author(s)
  Akagi, J., Cho, Y-M., Toyoda, T., Mizuta, Y., Yokoi, M., Hanaoka, F., Ohmori, H., Ogawa, K.
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17K00551
[Presentation] Chromatin remodeling factors contribute to the function of human DNA polymerase η in the cells treated with cisplatin2017
- Author(s)
  Yokoi, M., Sugasawa, K., Hanaoka, F.
- Organizer
  第76回　日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-26340028
[Presentation] 損傷乗り越え型DNAポリメラーゼ　イータ・イオタ・カッパ三重欠損細胞を用いた新規遺伝毒性試験法の研究2017
- Author(s)
  赤木純一、横井雅幸、Young-Man Cho、豊田武士、大森治夫、花岡文雄、小川久美子
- Organizer
  第3回　次世代を担う若手のためのレギュラトリーサイエンスフォーラム
- Data Source
  KAKENHI-PROJECT-26340028
[Presentation] Contribution of Polκ to tumorigenesis in the forestomach of benzo[a]pyrene-fed mice2017
- Author(s)
  Akagi, J., Cho, Y-M., Toyoda, T., Mizuta, Y., Yokoi, M., Hanaoka, F., Ohmori, H., Ogawa, K.
- Organizer
  ComBio2017
- Data Source
  KAKENHI-PROJECT-17K00551
[Presentation] ヒトPolηの構造的特徴と損傷乗り越え活性の連関2016
- Author(s)
  横井雅幸
- Organizer
  生物ゲノム安定維持の分子機構
- Place of Presentation
  国立遺伝学研究所
- Year and Date
  2016-10-24
- Data Source
  KAKENHI-PROJECT-26340028
[Presentation] Structure and function relations of human DNA polymerase η: mutations of the finger or little finger domains alter lesion bypass efficiencies2016
- Author(s)
  Yokoi, M., Onaka, S., Mishima, K., Yang, W., Hanaoka, F.
- Organizer
  The 10th 3R Symposium
- Place of Presentation
  島根県松江市
- Year and Date
  2016-11-13
- Data Source
  KAKENHI-PROJECT-26340028
[Presentation] Functional analysis of human DNA polymerase η harboring mutations in the palm domain2016
- Author(s)
  Yokoi, M., Mishima, K., Noda, C., Nishimura, J., Yang, W., Hanaoka, F.
- Organizer
  第39回　日本分子生物学会
- Place of Presentation
  神奈川県横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26340028
[Presentation] Mutations of the finger or little-finger domains in human Polη alter lesion bypass efficiencies when copying DNA containing cyclobutane pyrimidine dimer2015
- Author(s)
  Yokoi, M., Onaka, S., Mishima, K., Hanaoka, F.
- Organizer
  第38回　日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26340028
[Presentation] High concentration of dATP attenuated the catalytic rate and efficiency of translesion2015
- Author(s)
  Yokoi, M., and Hanaoka, F.
- Organizer
  第74回　日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26340028
[Presentation] Roles of DNA polymerase η and ι in UV-induced mutagenesis of skin cells and tissues2015
- Author(s)
  149.Sakurai, Y., Yokoi, M., Tsukamoto, T., Wei, M., Wanibuchi, H., Murakumo, Y., Hanaoka, F.
- Organizer
  第104回　日本病理学会総会
- Place of Presentation
  横浜
- Year and Date
  2015-04-30
- Data Source
  KAKENHI-PROJECT-26340028
[Presentation] Unidentified function of DNA polymerase η and ι in cellular sensitivity to an oxidizing agent potassium bromate2015
- Author(s)
  Dotsu, K., Ohkumo, T., Yokoi, M., and Hanaoka, F.
- Organizer
  第38回　日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26340028
[Presentation] Hypersensitivity of Pols η, ι, and κ triple knockout cells to mutagens is a valuable indicator of genotoxicity2015
- Author(s)
  150.Akagi, J., Yokoi, M., Cho, Y-M., Toyoda, T., Hanaoka, F., Ogawa, K
- Organizer
  第74回　日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26340028
[Presentation] アミノ酸置換変異体を用いたヒトPolηの機能解析2014
- Author(s)
  横井雅幸
- Organizer
  国立遺伝学研究所研究集会
- Place of Presentation
  三島
- Year and Date
  2014-11-07
- Invited
- Data Source
  KAKENHI-PROJECT-26340028
[Presentation] Roles of mammalian DNA polymerase η and ι UV-induced mutagenesis.2014
- Author(s)
  Hanaoka, F., Sakurai, Y.,Yokoi, M.
- Organizer
  3R Symposium
- Place of Presentation
  御殿場
- Year and Date
  2014-11-18
- Data Source
  KAKENHI-PROJECT-26340028
[Presentation] Physiological role of TLS polymerases in mouse skin upon UV irradiation2014
- Author(s)
  Yokoi, M., Sakurai, Y., Hando, N., Morita, D., and Hanaoka, F
- Organizer
  International Conference, Kyoto, 2014: Replication, Repair and Recombination; coupling mechanisms and chromatin dynamics for genome integrity
- Place of Presentation
  京都
- Invited
- Data Source
  KAKENHI-PROJECT-22249005
[Presentation] Rev1-dependent activity of Polκcontributes to translesion synthesis past UV-induced DNA lesions2012
- Author(s)
  Suzuki, K., Akagi, J., Ohashi, E., Yokoi, M., Ohmori,H., and Hanaoka, F
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Year and Date
  2012-12-12
- Data Source
  KAKENHI-PROJECT-22510063
[Presentation] Functional roles of mammalian DNA polymeraseη, the product of the XP-V responsible gene2012
- Author(s)
  Hanaoka, F., Yokoi, M
- Organizer
  3rd Erling Seeberg Symposium
- Place of Presentation
  Trondheim and Orland, Norway
- Invited
- Data Source
  KAKENHI-PROJECT-22249005
[Presentation] Physiological role of DNA polymerase ι in suppression of UV-induced mutagenesis.2012
- Author(s)
  Yokoi, M., Ito, W., Otomo, M., Hanaoka, F.
- Organizer
  第8回　3R Symposium
- Place of Presentation
  兵庫県立淡路夢舞台国際会議場
- Data Source
  KAKENHI-PROJECT-22510063
[Presentation] Functional roles of mammalian DNA polymerase η, the product of the XP-V responsible gene2012
- Author(s)
  Hanaoka, F., Yokoi, M
- Organizer
  3rdErling Seeberg Symposium
- Place of Presentation
  Trondheim and Orland, Norway
- Year and Date
  2012-06-21
- Data Source
  KAKENHI-PROJECT-22510063
[Presentation] Physiological role of DNA polymerase ι in suppression of UV-induced mutagenesis2012
- Author(s)
  Yokoi, M., Ito, W., Otomo,M., and Hanaoka, F
- Organizer
  第8回 3R Symposium
- Place of Presentation
  淡路夢舞台
- Year and Date
  2012-11-27
- Data Source
  KAKENHI-PROJECT-22510063
[Presentation] ηPhysiological role of DNA polymerase η-REV1 interaction in mammalian cells2012
- Author(s)
  Yokoi, M., and Hanaoka, F
- Organizer
  Cantoblanco Workshops
- Place of Presentation
  Madrid, Spain
- Year and Date
  2012-06-06
- Data Source
  KAKENHI-PROJECT-22510063
[Presentation] Alternative translesion synthesis pathway via interaction between stalled DNA polymeraseηand REV12012
- Author(s)
  Hanaoka, F., Yokoi, M
- Organizer
  8th 3R Symposium
- Place of Presentation
  淡路島
- Invited
- Data Source
  KAKENHI-PROJECT-22249005
[Presentation] Physiological role of DNA polymeraseη-REV1 interaction in mammalian cells2012
- Author(s)
  Yokoi, M., Hanaoka, F
- Organizer
  Cantoblanco Workshops : Polymerases Involved in DNA Replication, Repair and Mutagenesis
- Place of Presentation
  Madrid, Spain
- Invited
- Data Source
  KAKENHI-PROJECT-22249005
[Presentation] Alternative translesion synthesis pathway via interaction between stalled DNA polymerase η and REV12012
- Author(s)
  Hanaoka, F., Yokoi, M
- Organizer
  第8回 3R Symposium
- Place of Presentation
  淡路夢舞台
- Year and Date
  2012-11-27
- Data Source
  KAKENHI-PROJECT-22510063
[Presentation] Involvement of DNA polymerase η-REV1 interaction in a part of error-prone translesion DNA synthesis2012
- Author(s)
  Hanaoka, F., Yokoi, M
- Organizer
  US-Japan DNA Repair Workshop
- Place of Presentation
  Leesburg, USA
- Year and Date
  2012-04-13
- Data Source
  KAKENHI-PROJECT-22510063
[Presentation] Physiological role of DNA polymerase η-REV1 interaction in mammalian cells.2012
- Author(s)
  Yokoi, M,, Hanaoka, F.
- Organizer
  Cantoblanco Workshops
- Place of Presentation
  Madrid, Spain
- Invited
- Data Source
  KAKENHI-PROJECT-22510063
[Presentation] Involvement of DNA polymeraseη-REV1 interaction in a part of error-prone translesion DNA synthesis2012
- Author(s)
  Hanaoka, F., Yokoi, M
- Organizer
  US-Japan DNA Repair Workshop
- Place of Presentation
  Leesburg, USA
- Invited
- Data Source
  KAKENHI-PROJECT-22249005
[Presentation] Establishment of mouse expressing inactive DNA polymerase η2012
- Author(s)
  Morita, D., Sakurai, Y., Sakayoshi, N., Ito, W., Yokoi, M., Hanaoka, F
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Year and Date
  2012-12-12
- Data Source
  KAKENHI-PROJECT-22510063
[Presentation] Stalled polη at its cognate substrate emerged an alternative TLS pathway via interaction with REV12011
- Author(s)
  Ito, W., Yokoi, M., Mitani, H., Ohmori,H., Hanaoka, F
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22510063
[Presentation] Unidentified function of DNA polymerase η and ι in cellular sensitivity to an oxidizing agent potassium bromate2011
- Author(s)
  Dotsu, K., Sakurai, Y., Ohkumo, T., Yokoi, M., and Hanaoka, F
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22510063
[Presentation] Roles of DNA polymerase η and ι in translesion synthesis past UVB-induced DNA lesions: division of labor at mouse skin2011
- Author(s)
  Yokoi, M., Sakurai, Y., and Hanaoka, F
- Organizer
  Responses to DNA Damage: From MolecularMechanism to Human Disease
- Place of Presentation
  The Netherlands
- Year and Date
  2011-04-05
- Data Source
  KAKENHI-PROJECT-22510063
[Presentation] An alternative TLS pathway for UV-induced DNA damages induced by Polη-REV1 interaction2011
- Author(s)
  Yokoi, M., Ito, W., and Hanaoka, F
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22510063
[Presentation] Roles of DNA polymerase η and ι in translesion synthesis past UVB-induced DNA lesions : division of labor at mouse skin2011
- Author(s)
  Yokoi, M., Sakurai, Y., Hanaoka, F.
- Organizer
  Responses to DNA Damage : From Molecular Mechanism to Human Disease
- Place of Presentation
  Egmond aan Zee, The Netherlands
- Year and Date
  2011-04-05
- Data Source
  KAKENHI-PROJECT-22510063
[Presentation] Polκ contributes to suppression of UV-induced mutagenesis2011
- Author(s)
  Suzuki, K., Akagi, J., Ohashi, E., Yokoi, M., Ohmori.H., and Hanaoka, F
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22510063
[Presentation] An alternative TLS pathway for UV-induced DNA damages induced by Polη-REV1 interaction2011
- Author(s)
  Yokoi, M., Ito, W., Hanaoka, F.
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜(招待講演)
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-22510063
[Presentation] Tissue-specific roles of DNA polymerase η and ι in UV-induced mutagenesis and DNA damage tolerance2011
- Author(s)
  Sakurai, Y., Yokoi, M., Ohkumo, T., Hanaoka, F
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22510063
[Presentation] Analysis of back-up mechanism in translesion synthesis past CPD in the absence of Polη activity2010
- Author(s)
  Ito, W., Yokoi, M., Mitani, H., Hanaoka, F
- Organizer
  BMB2010
- Place of Presentation
  神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-22510063
[Presentation] Roles of DNA polymerase η and ι in translesion synthesis past UVB-induced DNA lesions in vivoGordon Research Conference2010
- Author(s)
  Yokoi, M., Sakurai, Y., Tsukamoto, T., Tatematsu, M., Hanaoka, F
- Organizer
  Mutagenesis
- Place of Presentation
  Waterville, USA
- Year and Date
  2010-08-04
- Data Source
  KAKENHI-PROJECT-22510063
[Presentation] Roles of DNA polymeraseη and ι in UV-induced mutagenesis and DNA damage tolerance2010
- Author(s)
  Sakurai, Y., Yokoi, M., Ohkumo, T., Tsukamoto, T., Tatematsu, M., Wei, M., Wanibuchi, H., Hanaoka, F
- Organizer
  BMB2010
- Place of Presentation
  神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-22510063
[Presentation] UV照射DNAの損傷乗り越え複製におけるDNAポリメラーゼイータとイオタの生体内での役割2010
- Author(s)
  Sakurai, Y., Yokoi, M., Tsukamoto, T., Tatematsu, M., Wei, M., Wanibuchi, H., Hanaoka, F
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-22510063
[Presentation] Tissue specific function of DNA polymerases η and ι in suppression of UV-induced skin tumor and mutagenesis2010
- Author(s)
  Yokoi, M., Sakurai, Y., and Hanaoka, F
- Organizer
  The 7th3R Symposium
- Place of Presentation
  富山カンファレンスセンター(富山県)
- Year and Date
  2010-10-26
- Data Source
  KAKENHI-PROJECT-22510063
[Presentation] UVB照射DNAの損傷乗り越え複製におけるDNAポリメラーゼηとιの生体内での役割2010
- Author(s)
  櫻井靖高、横井雅幸、大雲剛志、道津貫太郎、塚本徹哉、立松正衛、花岡文雄
- Organizer
  第62回日本細胞生物学会大会
- Place of Presentation
  大阪
- Year and Date
  2010-05-19
- Data Source
  KAKENHI-PROJECT-22510063
[Presentation] Unidentified function of DNA polymeraseη and ι in cellular sensitivity to potassium bromate2010
- Author(s)
  Dotsu, K., Sakurai, Y., Ohkumo, T., Yokoi, M., Hanaoka, F
- Organizer
  BMB2010
- Place of Presentation
  神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-22510063
[Presentation] CPDの損傷乗り越え複製におけるDNAポリメラーゼηとREV1との相互作用の役割2010
- Author(s)
  伊藤若菜、横井雅幸、坂吉伸隆、星本英史、三谷啓志、花岡文雄
- Organizer
  第62回日本細胞生物学会大会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22510063
[Presentation] ノックアウトマウスを用いた紫外線損傷乗り越え複製の解析2010
- Author(s)
  横井雅幸
- Organizer
  平成22年度京都大学原子炉実験所専門研究会
- Place of Presentation
  大阪
- Year and Date
  2010-09-11
- Data Source
  KAKENHI-PROJECT-22510063
[Presentation] 損傷乗り越え複製の分子機構-DNAポリメラーゼ・イータを中心に-2007
- Author(s)
  花岡文雄、横井雅幸、大雲剛志、金尾梨絵、赤木純一、益谷央豪
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会(BMB2007)、シンポジウム「DNA修復研究の最前線」
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-17013053
[Presentation] Roles of translesion synthesis polymerases eta and iota in UV-induced mutagenesis in mice
- Author(s)
  Sakurai Y, Yokoi M, Murakumo Y, Hanaoka F
- Organizer
  ZING Conferences DNA Polymerases: Biology, Diseases and Biomedical Applications Conference 2014
- Place of Presentation
  Cambridge, UK
- Year and Date
  2014-08-31 – 2014-09-04
- Invited
- Data Source
  KAKENHI-PLANNED-22131008
[Presentation] Roles of DNA polymerases eta and iota in UV-induced mutagenesis.
- Author(s)
  Sakurai Y, Yokoi M, Hanaoka F
- Organizer
  5th US-Japan DNA Repair Meeting
- Place of Presentation
  鳴門、徳島
- Year and Date
  2014-10-28 – 2014-10-31
- Invited
- Data Source
  KAKENHI-PLANNED-22131008
[Presentation] Roles of mammalian DNA polymerases eta and iota in UV-induced mutagenesis.
- Author(s)
  Hanaoka F, Sakurai Y, Yokoi M
- Organizer
  The 9th 3R Symposium
- Place of Presentation
  御殿場
- Year and Date
  2014-11-17 – 2014-11-21
- Invited
- Data Source
  KAKENHI-PLANNED-22131008

1. OHKUMA Yoshiaki (70192515)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
2. HANAOKA Fumio (50012670)

# of Collaborated Projects: 6 results

# of Collaborated Products: 30 results
3. MASUTANI Chikahide (40241252)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
4. AKAGI Jun-ichi (60512556)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
5. IWAI Shigenori (10168544)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. EKI Toshihiko (40192512)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KANAO Rie

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 池畑広伸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 山本雅之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 中津可道

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 青田聖恵

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 續輝久

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

YOKOI Masayuki 横井 雅幸

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ゲノム複製の停止と再開に関連したTLS機構とクロマチン構造変換のクロストークPrincipal Investigator

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Studies on the molecular mechanisms to regulate the resumption of stalled replication by translesion synthesis at DNA damage sitesPrincipal Investigator

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Functional analyses of translesion synthesis DNA polymerase Poleta based on its structural featuresPrincipal Investigator

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Physiological role of protein-protein interaction among translesion DNA polymerases in cellular resistance to ultraviolet lightPrincipal Investigator

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DNA修復因子と中心体構成因子の遺伝的相互作用とその細胞生物学的意義Principal Investigator

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分裂酵母のDNA修復と損傷乗り越え複製制御機構の分子遺伝学的解析Principal Investigator

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YOKOI Masayuki 横井雅幸