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YOSHIDA Shonen
吉田 松年
Connect your ORCID iD
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Alternative Names
よし田 松年 ヨシダ ショウネン
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Researcher Number
70090420
Affiliation (based on the past Project Information)
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1992 – 2000: 名古屋大学, 医学部, 教授
1995: 名古屋大学, 医学部・病態制御研究施設, 教授
1987 – 1991: 名古屋大学, 医学部, 助教授
1986: 名大, 医学部, 助教授
Review Section/Research Field
Principal Investigator
Pathological medical chemistry
/
Biological Sciences
Except Principal Investigator
Structural biochemistry
/
Biological pharmacy
/
物質生物化学
/
Molecular biology
/
Pathological medical chemistry
/
General medical chemistry
Keywords
Principal Investigator
DNAポリメラーゼα / cーmycタンパク / 試験管内DNA複製系 / RBタンパク / DNAプライマーゼ / スフィンゴシン / テロメラーゼ / 細胞増殖 / 阻害剤 / DNAアフィニティカラム
…
More
/ 自律増殖配列 / HBVXタンパク / 制がん剤 / プライマーゼ / cdk / Rbタンパク / PIP / カルジオリピン / DNA polymerase alpha / DNA replication / 自律増殖配列結合タンパク / 試験管内複製系 / CDC28 / 2 / ヌクレオソ-ム / SV40ミニクロモソ-ム / DNAポリメラ-ゼ / プライマ-ゼ / DNAヘリカ-ゼ / トポイソメラ-ゼ / SV40DNA / DNAヘリカーゼ / T抗原 / 色素性乾皮症 / DNA修復 / アポトーシス / イソチアゾロン / Rb蛋白 / リン酸化 / G1期 / S期 / 複製工場 / サイクリン / 細胞周期 / 複製忠実度 / DNAポリメラーゼδ / DNAポリメラーゼε / 発がん / SNP / DNAポリメラ-ゼα / トポイソメラ-ゼI / ホスファチジルイノシト-ル / IP_2 / ホスホリパ-ゼC / 再生肝 / DNA複製 / PlP / lP_2 / P1P / 1P_2 / ホスフォリパ-ゼC / Phospholipase C / IP2 / Regenerating Liver / Nuclei / Phosphotidylinositides / 網膜芽細胞腫遺伝子Rb / バキュロウィルス / cyclin / 複製因子 / RP-A / 網膜芽細胞種遺伝子RB蛋白 / バキュロウイルス / Raji細胞 / ポリADPリボシル化酵素 / 蛋白リン酸化 / フォスファターゼIIA / Rb protein / protein-protein interaction / protein phosphoryaltion / DNAポリメラーゼ / トポイソメラーゼ / フォスファチジルイノシトール / トポイソメラーゼI / ゲルシフトアッセイ / カルシウムイオン / モノクローナル抗体 / 核マトリクス / リン脂質 / Human ARS / Human c-myc gene / Raji cell / DNA polymerase / Topoisomerase I Cardiolipin / Phosphatidylinositol
…
More
Except Principal Investigator
DNA複製 / 細胞核 / 再生肝 / アポトーシス / Cdc7 / DNAポリメラーゼ / 抗HIVヌクレオシド / 副作用評価 / CFUーE / CFUーG / 巨核球 / 骨髄抑制 / ホスホリパ-ゼC / イノシト-ルリン脂質 / ホスファチジルイノシト-ルモノリン酸 / ホスファチジルイノシト-ル / ゲノム複製 / 複製開始点 / ARS配列 / 複製遺伝子 / 複製酵素 / ホスホリパーゼA_2 / 肝癌 / 胸腺腫発生遺伝子 / Tsr-1 / 胸腺増大遺伝子 / Ten-1 / Ten-2 / 胸腺サイズ抑制遺伝子 / 胸腺腫発生感受性遺伝子Tsr-1 / 胸腺増大遺伝子Ten-1,Ten-2 / BUF / Mna系ラット / 複製蛋白 / 複製起点 / 染色体分配 / 細胞分裂 / ライセンス因子 / スフィンゴシン / DNAプライマーゼ / 変異原性ヌクレオチド / DNAポリメラーゼγ / DNAポリメラーゼα / DNAポリメラーゼδ / DNAポリメラーゼε / LacZα遺伝子 / 忠実度 / 真核生物 / セラミダーゼ / 細胞株 / アフリカツメガエル / ホスホリパーゼ D / 核膜 / ホスファチジン酸 / 真核生物染色体複製機構 / Leading鎖複製装置 / Lagging鎖複製装置 / DNAヘリカーゼ / Mcm2-7蛋白複合体 / Dbf4プロテインキナーゼ / チェックポイント制御 / Bloom症候群原因遺伝子産物 / ヘリカーゼ / Mcm蛋白複合体 / Dbf4複合体 / 真核生物染色体DNA複製 / Leading鎖合成装置 / Lagging鎖合成装置 / RF-C複合体 / PCNA / 細胞周期チェックポイント / Eukaryotic chromosomal DNA replication / Leading strand synthesis apparatus / Lagging strand synthesis apparatus / DNA helicase / Mcm2-7 complex / Dbf4 protein kinase / Checkpoint control / ミトコンドリア巨大化 / フリーラジカル / TEMPO誘導体 / 酸素ラジカル / 培養細胞 / フリーラジカルスカベンジャー / 微小管 / taxol / nocodazole / acetylated α-tubulin / coenzymeQ_<10> / ミトコンドリア形態制御遺伝子 / mmml / mdm10 / スカベンジャー / megamitochondria / free radicals / scavengers / apoptosis / TEMPO derivatives / culture cells / 4-OH-TEMPO / 転写 / 複製忠実度 / DNA合成 / 塩基置換 / フレームシフト / ゲノムインスタビリティー / RNAポリメラーゼ / Taq / セントラルドグマ / DNA polymerase / DNA replication / transcription / replication fidelity / DNA synthesis / base substitution / frameshift / genome instability
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Research Projects
(
26
results)
Co-Researchers
(
43
People)
Project Start Year (Newest)
Project Start Year (Oldest)
ヒト透過性細胞を用いたDNA複製装置の免疫組織化学的解析
Principal Investigator
Principal Investigator
吉田 松年
Project Period (FY)
2000
Research Category
Grant-in-Aid for Scientific Research on Priority Areas (C)
Review Section
Biological Sciences
Research Institution
Nagoya University
ヒト透過性細胞を用いたDNA複製装置の免疫組織化学的解析
Principal Investigator
Principal Investigator
吉田 松年
Project Period (FY)
1999
Research Category
Grant-in-Aid for Scientific Research on Priority Areas (A)
Research Institution
Nagoya University
DNAプライマーゼ及びテロメラーゼを分子標的としたがん細胞増殖抑制
Principal Investigator
Principal Investigator
吉田 松年
Project Period (FY)
1998
Research Category
Grant-in-Aid for Scientific Research on Priority Areas (A)
Research Institution
Nagoya University
アフリカツメガエル卵無細胞系の核膜形成とホスホリパーゼD
Principal Investigator
小泉 恵子
Project Period (FY)
1998
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Structural biochemistry
Research Institution
Nagoya University
Molecular mechanism of free radical-induced apoptosis
Principal Investigator
WAKABAYASHI Takashi
Project Period (FY)
1998 – 2000
Research Category
Grant-in-Aid for Scientific Research (B).
Research Field
Pathological medical chemistry
Research Institution
Nagoya University
Isolation and characterization of an enhanced ribonucleotide incorporation in a mutant DNA polymerase
Principal Investigator
SUZUKI motoshi
Project Period (FY)
1998 – 1999
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
General medical chemistry
Research Institution
Nagoya University
DNAプライマーゼ及びテロメラーゼを標的とする新規阻害物質のがん細胞増殖制御
Principal Investigator
Principal Investigator
吉田 松年
Project Period (FY)
1997
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Nagoya University
DNAプライマーゼ及びテロメラーゼを分子標的とする新規阻害物質の探索
Principal Investigator
Principal Investigator
吉田 松年
Project Period (FY)
1996
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Nagoya University
変異原性ヌクレオチドのミトコンドリアDNAポリメラーゼγにおける挙動解析
Principal Investigator
伊豆田 俊二
Project Period (FY)
1996
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Structural biochemistry
Research Institution
Kumamoto University
核に存在するセラミダーゼの構造と機能(アポトーシスにおける役割)
Principal Investigator
小泉 恵子
Project Period (FY)
1996
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Biological pharmacy
Research Institution
Nagoya University
Molecular Mechanism of Chromosomal DNA Replication Apparatus
Principal Investigator
SUGINO Akio
Project Period (FY)
1996 – 1999
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Research Institute for Microbial Diseases, Osaka University
胸腺腫発生遺伝子Tsr-1の分子生物学的研究
Principal Investigator
松山 睦司
Project Period (FY)
1995
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Fujita Health University
細胞複製装置:染色体の複製・分配機構
Principal Investigator
平賀 壯太
Project Period (FY)
1995
Research Category
Grant-in-Aid for Co-operative Research (B)
Research Field
Molecular biology
Research Institution
Kumamoto University
スフィンゴシンによるDNA複製阻害機構の解析とがん化学療法への応用
Principal Investigator
小泉 恵子
Project Period (FY)
1995
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Biological pharmacy
Research Institution
Nagoya University
Regulation of DNA polymerase alpha-primase by interaction with nuclear proteins
Principal Investigator
Principal Investigator
YOSHIDA Shonen
Project Period (FY)
1995 – 1997
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Pathological medical chemistry
Research Institution
Nagoya University
胸腺腫発生遺伝子Tsr-1の分子生物学的研究
Principal Investigator
松山 睦司
Project Period (FY)
1994
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Nagoya University
細胞核に存在する新しいホスホリパーゼA_2の構造と機能
Principal Investigator
小泉 恵子
Project Period (FY)
1993
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Structural biochemistry
Research Institution
Nagoya University
DNA複製反応の促進及び抑制のメカニズムと癌化
Principal Investigator
Principal Investigator
吉田 松年
Project Period (FY)
1992
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Nagoya University
ゲノム複製開始の制御
Principal Investigator
吉川 寛
Project Period (FY)
1992 – 1994
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Nara Institute of Science and Technology
Osaka University
DNA複製反応の促進及び抑制のメカニズムと癌化
Principal Investigator
Principal Investigator
吉田 松年
Project Period (FY)
1991
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Nagoya University
細胞核に存在する新しいイノシト-ルリン脂質特異的ホスホリパ-ゼCの構造と機能
Principal Investigator
小泉 惠子
Project Period (FY)
1991
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
物質生物化学
Research Institution
Nagoya University
DNA複製反応の促進及び抑制のメカニズムと癌化
Principal Investigator
Principal Investigator
吉田 松年
Project Period (FY)
1990
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Nagoya University
Regulation of eukaryotic DNA replication by phosphotidylinosities.
Principal Investigator
Principal Investigator
YOSHIDA Shonen
Project Period (FY)
1990 – 1991
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Pathological medical chemistry
Research Institution
Nagoya University
試験管内DNA複製系を用いた癌遺伝子作用の研究
Principal Investigator
Principal Investigator
吉田 松年
Project Period (FY)
1989
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Nagoya University
抗エイズヌクレオシドの主作用、副作用の解析と予知並びに新設計のためのシステム開発
Principal Investigator
永井 美之
Project Period (FY)
1989
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Nagoya University
In vitro Replication of human chromosomal DNA and its regulation.
Principal Investigator
Principal Investigator
YOSHIDA Shonen
Project Period (FY)
1986 – 1988
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Pathological medical chemistry
Research Institution
Laboratory of Cancer Cell Biology, Research Institute for Disease Mechanism and Control, Nagoya University School of Medicine
# of Projects (Dsc)
# of Projects (Asc)
1.
KOIZUMI Keiko
(00118027)
# of Collaborated Projects:
12 results
# of Collaborated Products:
0 results
2.
IZUTA Shunji
(50203047)
# of Collaborated Projects:
9 results
# of Collaborated Products:
0 results
3.
SUZUKI Motoshi
(80236017)
# of Collaborated Projects:
6 results
# of Collaborated Products:
0 results
4.
KOJIMA Kiyohide
(80073104)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
5.
SUGINO Akio
(90231737)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
6.
小池 克郎
(30085625)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
7.
秋山 徹
(70150745)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
8.
花岡 文雄
(50012670)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
9.
村手 隆
(30239537)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
10.
有賀 寛芳
(20143505)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
11.
新井 賢一
(00012782)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
12.
松山 睦司
(80073112)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
13.
武村 政春
(50303623)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
14.
TSURIMOTO Toshiki
(30163885)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
15.
SUGIMOTO Katsunori
(90192616)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
16.
OHMORI Haruo
(10127061)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
17.
WAKABAYASHI Takashi
(00079998)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
18.
NIKI Ichiro
(10262908)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
19.
HAYAKAWA Tetsuo
(80022838)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
20.
UMEKAWA Hayato
(90185059)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
21.
永井 美之
(20022874)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
22.
実吉 峯郎
(20002339)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
23.
斉藤 英彦
(20153819)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
24.
安藤 俊夫
(20012693)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
25.
中村 普武
(30109938)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
26.
吉川 寛
(70019876)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
27.
山口 和男
(00019879)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
28.
堀内 賢介
(70219210)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
29.
今本 文男
(00029761)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
30.
小笠原 直毅
(10110553)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
31.
堀内 嵩
(60108644)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
32.
加藤 秀樹
(30142053)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
33.
佐賀 信介
(40144141)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
34.
平賀 壯太
(40027321)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
35.
升方 久夫
(00199689)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
36.
松影 昭夫
(90019571)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
37.
滝澤 温彦
(60154944)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
38.
榎本 武美
(80107383)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
39.
真木 寿治
(20199649)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
40.
ISHIMI Yukio
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
41.
JERZY Krechn
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
42.
ZDZISLAW Wai
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
43.
MICHAL Wozni
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
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