NAGAI Yoshiyuki 永井美之

… Alternative Names

Researcher Number	20022874 … More / 20000874 Less
Other IDs
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Affiliation (based on the past Project Information) *help	2006: The Institute of Physical and Chemical Research, Research Center for Allergy and Immunology, Senior Scientist, 免役・アレルギー科学総合センター, 上級研究員 2006: 独立行政法人理化学研究所, 免疫・アレルギー科学総合研究センター, 上級研究員 2003 – 2005: 富山県衛生研究所, 所長 2002: 名古屋大学, 医学系研究科, 名誉教授 2001: 名古屋大学, 名誉教授 … More
Review Section/Research Field	Principal Investigator Virology / Biological Sciences Except Principal Investigator Virology / Applied veterinary science / Biological Sciences / General medical chemistry
Keywords	Principal Investigator HIV / 病原性 / HIV-1 / センダイウイルスベクター / ウイルスゲノム / パラミクソウイルス / ケモカイン受容体 / エイズ病態 / Paramyxovirus / ウイルス病原性 … More Except Principal Investigator パラミクソウイルス / 病原性 / エイズ / HIV-1 / 抗HIV剤 / 宿主因子 / C蛋白質 / 粒子形成 / HIV複製 / センダイウイルス / RNAレプリコン / ケモカイン / リバースジェネティクス / ウイルストロピズム / Signal Transduction / フリーラジカル / Sendai virus / RNA複製 / 免疫 / Cell Cycle / ウイルス分子進化 / 血液凝固第十因子 / PARAMYXOVIRUS / ウイルス感染病態 / RNA synthesis / 組織作り / トランスジェニックマウス / Immune response / paramyxovirus / バキユロウイルス / リコンビナントワクチニアウイルス / CPROTEIN / 癌 / Drug Design / V蛋白質 / リコンビニナント鶏痘ウイルス / 転写 / 国際学術 / ケモカイン受容体 / RIVERSE GENETICS / 制御 / 自然免疫 / Newcastle disease virus / 細胞周期 / International Scientific Research / ニュ-スレタ- / 細胞増殖 / 抗HIV免疫 / 複製 / 膜融合蛋白 / F蛋白前駆体 / pathogenicity / ヘモアグルチニンーノイラミニダ-ゼ / パラミキソウイルス / recombinant vaccinia virus / コレセプター / protection / インターフェロン / 癌遺伝子治療 / Chemokine / ニュ-カッスル病ウイルス / 癌化学療法 / Chemokine Receptor / 遺伝子治療 / PATHOGENESIS / fusion protein / V PROTEIN / Cell Adhesion / リコンビニナントワクチニアクウイルス / ウイルス発癌 / リードスルー / 翻訳 / reverse genetics / hemagglutinin-neuraminidase / AIDS Control / 化学発癌 / 膜融合タンパク / ウイルス活性化プロテア-ゼ / 海外派遣 / パーオキシナイトライト / CTL / NO / インフルエンザウイルス / リコンビナント鶏痘ウイルス / Pathophysiology / 遺伝子変異 / 病態 / recombinant fowlpox virus / Gene Therapy / 細胞社会学 / Interferon / Cancer / 細胞接着 / 薬品設計 / 重点領域研究 / ニワトリ胚 / 終結配列 / 情報交換 / SENDAI VIRUS / RNA合成 / ウイルスRNA / ポリオウイルス / 癌治療 / オルソミクソウイルス / ウイルス蛋白質 / HIV / 宿主分子 / 感染防御 / 膜融合(下)蛋白 / 薬剤耐性 / シンポジウム / Innate immunity / ドラッグデザイン / C protein / Information Exchange / プロトロンビン検 / シグナル伝達 / バキュロウイルス / baculovirus / Host Factors Less

Basic Research for AIDS control
- Principal Investigator
  
  UCHIYAMA Takashi
- Project Period (FY)
  2002
- Research Category
  
  特定領域研究
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Molecular Bases underlying Microbial Infections and the Host ResponsesPrincipal Investigator
- Principal Investigator
  
  NAGAI Yoshiyuki
- Project Period (FY)
  2001 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research
  Toyama Institute of Health
  Nagoya University
Analysis of Functional Regions on The Sendai Virus Genome
- Principal Investigator
  
  KATO Atsushi
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  National Institute of Infections Diseases
フリーラジカルによるウイルス遺伝子変異メカニズムの解明
- Principal Investigator
  
  赤池孝章
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Virology
- Research Institution
  Kumamoto University
Basic Research for AIDS control A01 ; Host factors necessary for HIV-1 replicationPrincipal Investigator
- Principal Investigator
  
  KOYANAGI Yoshio, 永井美之
- Project Period (FY)
  1998 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  TOHOKU UNIVERSITY
  The University of Tokyo
エイズの病態と制御に関する基礎研究柱2.病態のウイルス学的基盤Principal Investigator
- Principal Investigator
  
  永井美之
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
エイズの基礎研究の動向調査と将来展望
- Principal Investigator
  
  内山卓
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Kyoto University
Gene manipulation of Sendai virus and development of Sendai virus vectorPrincipal Investigator
- Principal Investigator
  
  NAGAI Yoshiyuki
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Virology
- Research Institution
  The University of Tokyo
Molecular anatomy of Sendai virus
- Principal Investigator
  
  KATO Atsushi
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  The University of Tokyo
RNAレプリコン
- Principal Investigator
  
  野本明男
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
Pathogenesis and Control of AIDSPrincipal Investigator
- Principal Investigator
  
  NAGAI Yoshiyuki
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
エイズ研究の現状と展望Principal Investigator
- Principal Investigator
  
  永井美之
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  Virology
- Research Institution
  The University of Tokyo
Information Exchange on Cancer Research with North American
- Principal Investigator
  
  YAMAMOTO Tadashi
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  The University of Tokyo
ウイルス病原性の分子的基盤Principal Investigator
- Principal Investigator
  
  永井美之
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  Virology
- Research Institution
  The University of Tokyo
RNAレプリコン
- Principal Investigator
  
  野本明男
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Institution
  The University of Tokyo
ニワトリ胚における第十因子異所性発現の生物学的意義
- Principal Investigator
  
  後藤敏
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Nagoya University
マウス血清の抗HIV活性、活性物質の同定と作用機構Principal Investigator
- Principal Investigator
  
  永井美之
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Nagoya University
Studies of the ecology and pathogenicity of Newcastle disease virus.
- Principal Investigator
  
  MIKAMI Takeshi
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  Applied veterinary science
- Research Institution
  The university of Tokyo
「ウイルス病原性の分子的基盤」研究推進のための調査研究Principal Investigator
- Principal Investigator
  
  永井美之
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  Virology
- Research Institution
  Nagoya University
抗エイズヌクレオシドの主作用、副作用の解析と予知並びに新設計のためのシステム開発Principal Investigator
- Principal Investigator
  
  永井美之
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Nagoya University
Studies on the Host Proteases which Determine Viral Spreading and Tropism.Principal Investigator
- Principal Investigator
  
  NAGAI Yoshiyuki
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  Nagoya University
Molecular Biology of Paramyxoviruses and the Viral PathogenesisPrincipal Investigator
- Principal Investigator
  
  NAGAI Yoshiyuki
- Project Period (FY)
  1985 – 1987
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  Virology
- Research Institution
  Nagoya University

All 2006 2005 2004 2003 2002 2001 Other

All Journal Article Book

[Book] In Biology of Negative Strand RNA Viruses, Y. Kawaoka(ed). Springer2004
- Author(s)
  Nagai Y., Kato, A
- Publisher
  Accessory genes of the paramyxoviridae, alarge family of nonsegmented negative-strand RNA viruses as a focus of active investigation by reverse genetics.
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Book] In virus Vectors, K. L. Hefferon(ed). Transworld Research Network.
- Author(s)
  Nagai Y., Inoue, M., Iida, A., Zhu Y-F., Hasegawa M., Kato A., Matsuno T.
- Publisher
  Sendai virus engineering : From reverse genetics to vector development.(in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] [Establishment and progress of Sendai virus engineering2006
- Author(s)
  Nagai Y, Kato A, Inoue M.
- Journal Title
  
  Tanpakushitsu Kakusan Koso 51(1)
  
  Pages: 27-37
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] [Establishment and progress of Sendai virus engineering2006
- Author(s)
  Nagai Y, Kato A, Inoue M.
- Journal Title
  
  tanpakushitsu Kakusan Koso 51(1)
  
  Pages: 27-37
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Establishment and progress of Sendai virus engineering2006
- Author(s)
  Nagai Y, Kato A, Inoue M.
- Journal Title
  
  Tanpakushitsu Kakusan Koso 51(1)
  
  Pages: 27-37
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Influence of glycosylation on the efficacy of an Env-based vaccine against simian immunodeficiency virus SIVmac239 in a macaque AIDS model.2005
- Author(s)
  Mori K, Sugimoto C, Ohgimoto S, Nakayama EE, Shioda T, Kusagawa S, Takebe Y, Kano M, Matano T, Yuasa T, Kitaguchi D, Miyazawa M, Takahashi Y, Yasunami M, Kimura A, Yamamoto N, Suzuki Y, Nagai Y
- Journal Title
  
  J. Virol. 79(16)
  
  Pages: 10386-10396
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Influence of glycosylation on the efficacy of an Env-based vaccine against simian immunodeficiency virus SIVmac239 in a macaque AIDS model2005
- Author(s)
  Mori K, Sugimoto C, Ohgimoto S, Nakayama EE, Shioda T Kusagawa S, Takebe Y, Kano M, Matano T, Yuasa T, Kitaguchi D Miyazawa M, Takahashi Y, Yasunami M, Kimura A, Yamamoto N Suzuki Y, Nagai Y.
- Journal Title
  
  J. Virol 79(16)
  
  Pages: 10386-10396
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] AIPI/Alix is a binding partner of Sendai virus C protein and facilitates virus budding.2005
- Author(s)
  Sakaguchi T, Kato A, Sugahara F, Shimazu Y, Inoue M, Kiyotani K, Nagai Y, Yoshida T.
- Journal Title
  
  J. virol. 79(14)
  
  Pages: 8933-8941
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] AIP1/Alix is a binding partner of Sendai virus C protein and facilitates virus budding.2005
- Author(s)
  Sakaguchi T, Kato A, Sugahara F, Shimazu Y, Inoue M, Kiyotani K, Nagai Y, Yoshida T.
- Journal Title
  
  J. Yirol. 79(14)
  
  Pages: 8933-8941
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Influence of glycosylation on the efficacy of an Env-based vaccine against aimian immunodeficiency virus SIVmac239 in a macaque AIDS model.2005
- Author(s)
  Mori K, Sugimoto C, Ohgimoto S, Nakayama EE, Shioda T, Kusagawa S, Takebe Y, Kano M, Matano T, Yuasa T, Kitaguchi D, Miyazawa M, Takahashi Y, Yasunami M, Kimura A, Yamamoto N, Suzuki Y, Nagai Y.
- Journal Title
  
  J.Virol. 79(16)
  
  Pages: 10386-10396
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] AIPI/Alix is a binding partner of Sendai virus C protein and facilitates virus budding.2005
- Author(s)
  Sakaguchi T, Kato A, Sugahara F, Shimizu Y, Inoue M, Kiyotani K, Nagai Y, Yoshida T.
- Journal Title
  
  J.Virol. 79(14)
  
  Pages: 8933-8941
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Accessory genes of the Paramyxoviridae, a large family of nonsegmented negative-strand RNA viruses, as a focus of active investigation by reverse genetics.2004
- Author(s)
  Nagai Y., Kato A.
- Journal Title
  
  Curr. Top. Microbiol. Immunol. 283
  
  Pages: 198-248
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Accessory genes of the paramyxoviridae, a large family of nonsegmented negative-strand RNA viruses, as focus of active investigation by reverse genetics.2004
- Author(s)
  Nagai Y, Kato A
- Journal Title
  
  Curr.Top.Microbial.Immunol. 283
  
  Pages: 197-248
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Accessory genes of the Paramyxoviridae, a large family of nonsegmented negative-strand RNA viruses, as a focus of active investigation by reverese genetics.2004
- Author(s)
  Nagai Y., Kato A.
- Journal Title
  
  Curr. Top. MicrobioL Immunol. 283
  
  Pages: 198-248
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Cytotoxic T Lymphocyte-based Control of Simian Immunodeficiency Virus Replication in a Preclinical AIDS Vaccine Trial.2004
- Author(s)
  Matano T, Kobayashi M, Igarashi H, Takeda A, Nakamura H, Kano M, Sugimoto C, Mori K, Iida A, Hirata T, Hasegawa M, Yuasa T, Miyazawa M, Takahashi Y, Yasunami M, Kimura A, O'Connor DH, Watkins DI, Nagai Y.
- Journal Title
  
  J Exp Med 199 (12)
  
  Pages: 1709-1718
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Cytotoxic T Lymphocyte-based Control of Simian Immunodeficiency Virus Replication in a Preclinical AIDS Vaccine Trial.2004
- Author(s)
  Matano T, Kobayashi M, Igarashi H, Takeda A, Nakamura H, Kano M, Sugimoto C, Mori K, Iida A, Hirata T, Hasegawa M, Yuasa T, Miyazawa M, Takahashi Y, Yasunami M, Kimura A, O'Connor DH, Watkins DI, Nagai Y.
- Journal Title
  
  J Exp Med 199(12)
  
  Pages: 1709-1718
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Cytotoxic T lymphocyte-based control of simian immunodeficiency virus replication in a preclinical AIDS vaccine trial.2004
- Author(s)
  Matano T, Kobayashi M, Igarashi H, Takeda A, Nakamura H, Kano M, Sugimoto C, Mori K, Iida A, Hirata T, Hasegawa M, Yuasa T, Miyazawa M, Takahashi Y, Yasunami M, Kimura A, O'Connor DH, Watkins DI, Nagai Y.
- Journal Title
  
  J.Exp.Med. 199(12)
  
  Pages: 1709-1718
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Accessory genes of the paramyxoviridae, a large family of nonsegmented negative-strand RNA viruses, as focus of active investigation by reverse genetics.2004
- Author(s)
  Kato A, Nagai Y
- Journal Title
  
  Curr Top Microbial Immunol 283
  
  Pages: 197-248
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Peotective efficacy of an AIDS vaccine, a single DNA priming followed by a single booster with a recombinant replication-defective Sendai virus vector, in a macaque AIDS model.2003
- Author(s)
  Takeda A, Igarashi H, Nakamura H, Kano M, Iida A, Hirata T, Hasegawa M, Nagai Y, Matano T.
- Journal Title
  
  J Virol. 77(17)
  
  Pages: 9710-9715
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] JNK-interacting protein 3 associates with Toll-like receptor 4 and is involved in LPS-mediated JNK activation2003
- Author(s)
  Matsuguchi T, Masuda A, Sugimoto K, Nagai Y, Yoshikai Y.
- Journal Title
  
  EMBO J. 22(17)
  
  Pages: 4455-4464
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] JNK-interacting protein 3 associates with Toll-like receptor 4 and is involved in LPS-mediated JNK activation.2003
- Author(s)
  Matsuguchi T, Masuda A, Sugimoto K, Nagai Y, Yoshikai Y.
- Journal Title
  
  EMBO J. 22(17)
  
  Pages: 4455-4464
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Protective efficacy of an AIDS vaccine, a single DNA primingfollowed by a single booster with a recombinant replication-defective Sendai virus vector, in a macaque AIDS model.2003
- Author(s)
  Takeda A, Igarashi H, Nakamura H, Kano M, Iida A, Hirata T, Hasegawa M, Nagai Y, Matano T.
- Journal Title
  
  J Virol. 77(17)
  
  Pages: 9710-9715
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Alteration of Sendai virus morphogenesis and nucleocapsid incorporation due to mutation of cysteine residues of the matrix protein.2002
- Author(s)
  Sakaguchi T, Uchiyama T, Huang C, Fukuhara N, Kiyotani K, Nagai Y, Yoshida T.
- Journal Title
  
  J Virol. 2002 Feb;76(4) : 1682-90.
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Fibroblast growth factor-2 determines severity of joint disease in adjuvant-induced arthritis in rats.2002
- Author(s)
  Yamashita A, Yonemitsu Y, Okano S, Nakagawa K, Nakashima Y, Irisa T, Iwamoto Y, Nagai Y, Hasegawa M, Sueishi K.
- Journal Title
  
  J Immunol. 168(1)
  
  Pages: 450-457
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Alteration of Sendai virus morphogenesis and nucleocapsid incorporation due to mutation of cysteine residues of the matrix protein.2002
- Author(s)
  Sakaguchi T, Uchiyama T, Huang C, Fukuhara N, Kiyotani K, Nagai Y, Yoshida T.
- Journal Title
  
  J Virol. 76(4)
  
  Pages: 1682-1690
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Naturally occurring deletional mutation in the C-terminal cytoplasmic tail of CCR5 affects surface trafficking of CCR5.2001
- Author(s)
  Shioda T, Nakayama EE, Tanaka Y, Xin X, Liu H, Kawana-Tachikawa A, Kato A, Sakai Y, Nagai Y, Iwamoto A
- Journal Title
  
  J Virol. 75(7)
  
  Pages: 3462-3468
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Quintuple deglycosylation mutant of simian immunodeficiency virus SIVmac239 in thesus macaques : robust primary replication, tightly contained chronic infection, and elicitation of potent immunity against the parental wild-rype strain.2001
- Author(s)
  Mori K, Yasutomi Y, Ohgimoto S, Nakasone T, Takamura S, Shioda T, Nagai Y.
- Journal Title
  
  J Virol. 75(9)
  
  Pages: 4023-4028
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Recembinant Sendai virus-mediated gene transfer to vasculature : a new class of efficient gene transfer vector to the vascular system.2001
- Author(s)
  Masaki I, Yonemitsu Y, Komori K, Ueno H, Nakashima Y, Nakagawa K, Fukumura M, Kato A, Hasan MK, Nagai Y, Sugimachi K, Hasegawa M, Sueishi K.
- Journal Title
  
  FASEB J. 15(7)
  
  Pages: 1294-1296
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Naturally occurring deletional mutation in the C-terminal cytoplasmic tail of CCR5 affects surface trafficking of CCR5.2001
- Author(s)
  Shioda T', Nakayama EE, Tanaka Y, Xin X, Liu H, Kawana-Tachikawa A, Kato A, Sakai Y, Nagai Y, Iwamoto A.
- Journal Title
  
  J Virol. 75(7)
  
  Pages: 3462-3468
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Rapid appearance of secondary immune responses and protection from acute CD4 depletion after a highly pathogenic immunodeficiency virus challenge in macaques vaccinated with a DNA prime/Senda virus vector boost regimen.2001
- Author(s)
  Matano T, Kano M, Nakamura H, Takeda A, Nagai Y.
- Journal Title
  
  J Virol. 75(23)
  
  Pages: 11891-11896
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Y2, the smallest of the Sendai virus C proteins, is fully capable of both cunteracting the antiviral action of interferons and inhibiting viral RNA synthesis.2001
- Author(s)
  Kato A, Ohnishi Y, Kohase M, Saito S, Tashiro M, Nagai Y.
- Journal Title
  
  J Virol. 75(8)
  
  Pages: 3802-10
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Recombinant Sendai virus-mediated gene transfer to vasculature: a new class of efficient gene transfer vector to the vascular system.2001
- Author(s)
  Masaki I, Yonemitsu Y, Komori K, Ueno H, Nakashima Y, Nakagawa K, Fukumura M, Kato A, Hasan MK, Nagai Y, Sugimachi K, Hasegawa M, Sueishi K.
- Journal Title
  
  FASEB J. 15(7)
  
  Pages: 1294-1296
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Augmentation of human immunodeficiency virus type 1 subtype E (CRF01_AE) multiple-drug resistance by insertion of a foreign 11-amino-acid fragment into the reverse transcriptase.2001
- Author(s)
  Sato H, Tomita Y, Ebisawa K, Hachiya A, Shibamura K, Shiino T, Yang R, Tatsumi M, Gushi K, Umeyama H, Oka S, Takabe Y, Nagai Y.
- Journal Title
  
  J Virol. 75(12)
  
  Pages: 5604-5613
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Rapid appearance of secondary immune responses and protection from acute CD4 depletion after a highly pathogenic immunodeficiency virus challenge in macaques vaccinated with a DNA prime/Sendai virus vector boost regimen.2001
- Author(s)
  Matano T, Kano M, Nakamura H, Takeda A, Nagai Y.
- Journal Title
  
  J Virol. 75(23)
  
  Pages: 11891-11896
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Y2, the smallest of the Sendai virus C proteins, is fully capable of both counteracting the antiviral action of interferons and inhibiting viral RNA synthesis.2001
- Author(s)
  Kato A, Ohnishi Y, Kohase M, Saito S, Tashiro M, Nagai Y.
- Journal Title
  
  J Virol. 75(8)
  
  Pages: 3802-10
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Augmentation of human immunodeficiency virus type 1 subtype E (CRFO1_AE) multiple-drug resistance by insertion of a foreign 11-amino-acid fragment into the reverse transcriptase.2001
- Author(s)
  Sato H, Tomita Y, Ebisawa K, Hachiya A, Shibamura K, Shiino T, Yang R, Tatsumi M, Gushi K, Umeyama H, Oka S, Takebe Y, Nagai Y.
- Journal Title
  
  J Virol. 75(12)
  
  Pages: 5604-5613
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Quintuple deglycosylation mutant of simian immunodeficiency virus SIVmac239 in rhesus macaques : robust primary replication, tightly contained chronic infection, and elicitation of potent immunity against the parental wild-type strain.2001
- Author(s)
  Mori K, Yasutomi Y, Ohgimoto S, Nakasone T, Takamura S, Shioda T', Nagai Y.
- Journal Title
  
  J Virol. 75(9)
  
  Pages: 4023-4028
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13225001

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NAGAI Yoshiyuki 永井 美之

永井 義之 ナガイ ヨシユキ

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Molecular Bases underlying Microbial Infections and the Host ResponsesPrincipal Investigator

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Basic Research for AIDS control A01 ; Host factors necessary for HIV-1 replicationPrincipal Investigator

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エイズの病態と制御に関する基礎研究 柱2.病態のウイルス学的基盤Principal Investigator

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Gene manipulation of Sendai virus and development of Sendai virus vectorPrincipal Investigator

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Pathogenesis and Control of AIDSPrincipal Investigator

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エイズ研究の現状と展望Principal Investigator

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ウイルス病原性の分子的基盤Principal Investigator

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NAGAI Yoshiyuki 永井美之

永井義之ナガイヨシユキ

エイズの病態と制御に関する基礎研究柱2.病態のウイルス学的基盤Principal Investigator