NAGAI Yoshiyuki 永井美之

… Alternative Names

永井義之ナガイヨシユキ

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Researcher Number	20022874
Other IDs
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Affiliation (based on the past Project Information) *help	2006: The Institute of Physical and Chemical Research, Research Center for Allergy and Immunology, Senior Scientist, 免役・アレルギー科学総合センター, 上級研究員 2006: 独立行政法人理化学研究所, 免疫・アレルギー科学総合研究センター, 上級研究員 2003 – 2005: 富山県衛生研究所, 所長 2002: 名古屋大学, 医学系研究科, 名誉教授 2001: 名古屋大学, 名誉教授 … More 2001: Toyama Institute of Health, Director, センター長 1999 – 2000: 国立感染症研究所, エイズセンター, センター長 1999: 国立感染症研究所, エイズ研究センター, センター長 1993 – 1999: 東京大学, 医科学研究所, 教授 1993 – 1994: 医科学研究所, 教授 1987 – 1992: Nagoya University School of Medicine, Professor, 医学部, 教授 1986: 名大, 医学部, 教授 Less
Review Section/Research Field	Principal Investigator Virology / Biological Sciences Except Principal Investigator Virology / Biological Sciences / Applied veterinary science / General medical chemistry
Keywords	Principal Investigator HIV / HIV-1 / 病原性 / エイズ / Paramyxovirus / パラミクソウイルス / センダイウイルスベクター / ケモカイン受容体 / ケモカイン / エイズ病態 … More / ウイルスゲノム / ウイルス病原性 / Pathogenicity / Spread in hosts / Biosynthesis / Genome structure / 抗原性相関地図 / モノクローン抗体 / 遺伝子一次構造 / 遺伝子クローニング / 抗原性 / 体内伝播 / 生合成 / 遺伝子構造 / coordination / support / planning / advice / evaluation / Host r Response / Infection / 感染制御方法論 / 寄生虫感染 / 細菌感染 / ウイルス感染 / 研究推進 / 研究支援 / 企画実施 / 評価・助言 / 宿主応答 / 感染 / Nuclear export / Integration / Retrovirus / Chemokine receptor / NF-kappaB / CD4(+) T cell / AIDS / サブタイプEゲノム / アクセサリー蛋白 / 逆転写 / 糖鎖 / CD26 / SDFA / SIV / サル細胞 / RANTES / 阻害剤 / Nef / gp41 / 核内因子 / REV / インテグレース / TAT / ゲノム / 核外移行 / インテグレーション / レトロウイルス / ケモカインレセプター / NF-κB / CD4陽性T細胞 / foreign gene expression / vector use / transcription control / pathogenicity / accessory genes / genetic engineering / Sendai virus / HIV-1 gp120 / V蛋白 / lac Z / 転写制御シグナル / 抗インターフェロン / アセンブリー / C蛋白 / 異種遺伝子発現 / ベクター化 / 転写制御 / アクセサリー遺伝子 / 遺伝子操作 / センダイウイルス / antiviral drugs / animal model / anti HIV response / Human genome / host factors / Viral genome / AIDS pathogenesis / HIV replication / 免疫応答 / 複製制御 / SCIDマウス / hPBL / Th2 / Th1 / 多型性 / 細胞侵入 / ワクチン / 化学療法 / 抗ウイルス剤 / 動物モデル / 抗HIV応答 / ヒトゲノム / 宿主因子 / AIDS病態 / HIV複製 / Viral tropism / Proteolytic activation / Orthomyxovirus / Fusion glycoprotein / Factor X / 血液凝固第10因子 / プロテア-ゼ / ミクソウイルス / ウイルス臓器向性 / ウイルス蔵器向性 / 切断活性化 / オルソミクソウイルス / 膜融合蛋白 / 第十因子 / ウイルス膜融合 / ウイルス侵入 / 持続感染 / 制御遺伝子 / センダイウイルスペクター / シアル酸 / V3 / V2 / 病態 / 体内変異 / エンベロープ糖蛋白 / HIV-変異 / 現状分析 / エイズ制御 / エイズの免疫学 / エイズのウイルス学 / エイズ研究 / 組織分布 / 宿主分子 / 宿主域 / 臓器向性 / ウイルス / マシノ-ス結合蛋白質 / 抗ウイルス活性 / マウス血清 / 骨髄抑制 / 巨核球 / CFUーG / CFUーE / 副作用評価 / 抗HIVヌクレオシド / 分子生物学 / ウイルス宿主相互作用 / ウイルス持続感染 / ウイルス変異 / ウイルストロピズム … More Except Principal Investigator 病原性 / パラミクソウイルス / HIV-1 / 粒子形成 / C蛋白質 / リバースジェネティクス / センダイウイルス / 宿主因子 / HIV複製 / 抗HIV剤 / ケモカイン / エイズ / RNAレプリコン / Innate immunity / Interferon / RNA synthesis / C protein / reverse genetics / paramyxovirus / Sendai virus / リードスルー / 終結配列 / 自然免疫 / インターフェロン / RNA合成 / Chemokine Receptor / Chemokine / AIDS Control / Immune response / Pathophysiology / Host Factors / 薬剤耐性 / 抗HIV免疫 / コレセプター / ケモカイン受容体 / 制御 / 免疫 / 病態 / PATHOGENESIS / CPROTEIN / V PROTEIN / RIVERSE GENETICS / PARAMYXOVIRUS / SENDAI VIRUS / V蛋白質 / Gene Therapy / Drug Design / Cell Adhesion / Cell Cycle / Signal Transduction / Information Exchange / Cancer / International Scientific Research / 細胞増殖 / 癌化学療法 / 癌遺伝子治療 / ドラッグデザイン / 情報交換 / 化学発癌 / 癌治療 / 細胞接着 / ウイルス発癌 / 遺伝子治療 / 薬品設計 / 細胞周期 / シグナル伝達 / 細胞社会学 / 癌 / 海外派遣 / 国際学術 / pathogenicity / protection / baculovirus / recombinant fowlpox virus / recombinant vaccinia virus / fusion protein / hemagglutinin-neuraminidase / Newcastle disease virus / バキユロウイルス / リコンビナント鶏痘ウイルス / リコンビナントワクチニアウイルス / F蛋白前駆体 / 膜融合(下)蛋白 / 感染防御 / バキュロウイルス / リコンビニナント鶏痘ウイルス / リコンビニナントワクチニアクウイルス / 膜融合蛋白 / ヘモアグルチニンーノイラミニダ-ゼ / ニュ-カッスル病ウイルス / ウイルス分子進化 / ウイルス感染病態 / 遺伝子変異 / パーオキシナイトライト / NO / フリーラジカル / CTL / HIV / トランスジェニックマウス / 宿主分子 / 複製 / ウイルス蛋白質 / ウイルスRNA / 翻訳 / 転写 / RNA複製 / プロトロンビン検 / ウイルストロピズム / 膜融合タンパク / オルソミクソウイルス / ニワトリ胚 / 血液凝固第十因子 / ウイルス活性化プロテア-ゼ / パラミキソウイルス / インフルエンザウイルス / ポリオウイルス / シンポジウム / ニュ-スレタ- / 組織作り / 重点領域研究 Less

Basic Research for AIDS control
- Principal Investigator
  
  UCHIYAMA Takashi
- Project Period (FY)
  2002
- Research Category
  
  特定領域研究
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Molecular Bases underlying Microbial Infections and the Host ResponsesPrincipal Investigator
- Principal Investigator
  
  NAGAI Yoshiyuki
- Project Period (FY)
  2001 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research
  Toyama Institute of Health
  Nagoya University
Analysis of Functional Regions on The Sendai Virus Genome
- Principal Investigator
  
  KATO Atsushi
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  National Institute of Infections Diseases
フリーラジカルによるウイルス遺伝子変異メカニズムの解明
- Principal Investigator
  
  赤池孝章
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Virology
- Research Institution
  Kumamoto University
Basic Research for AIDS control A01 ; Host factors necessary for HIV-1 replicationPrincipal Investigator
- Principal Investigator
  
  KOYANAGI Yoshio, 永井美之
- Project Period (FY)
  1998 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  TOHOKU UNIVERSITY
  The University of Tokyo
エイズの病態と制御に関する基礎研究柱2.病態のウイルス学的基盤Principal Investigator
- Principal Investigator
  
  永井美之
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
エイズの基礎研究の動向調査と将来展望
- Principal Investigator
  
  内山卓
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Kyoto University
Gene manipulation of Sendai virus and development of Sendai virus vectorPrincipal Investigator
- Principal Investigator
  
  NAGAI Yoshiyuki
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Virology
- Research Institution
  The University of Tokyo
Molecular anatomy of Sendai virus
- Principal Investigator
  
  KATO Atsushi
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  The University of Tokyo
RNAレプリコン
- Principal Investigator
  
  野本明男
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
Pathogenesis and Control of AIDSPrincipal Investigator
- Principal Investigator
  
  NAGAI Yoshiyuki
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
エイズ研究の現状と展望Principal Investigator
- Principal Investigator
  
  永井美之
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  Virology
- Research Institution
  The University of Tokyo
Information Exchange on Cancer Research with North American
- Principal Investigator
  
  YAMAMOTO Tadashi
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  The University of Tokyo
ウイルス病原性の分子的基盤Principal Investigator
- Principal Investigator
  
  永井美之
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  Virology
- Research Institution
  The University of Tokyo
RNAレプリコン
- Principal Investigator
  
  野本明男
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Institution
  The University of Tokyo
ニワトリ胚における第十因子異所性発現の生物学的意義
- Principal Investigator
  
  後藤敏
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Nagoya University
マウス血清の抗HIV活性、活性物質の同定と作用機構Principal Investigator
- Principal Investigator
  
  永井美之
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Nagoya University
Studies of the ecology and pathogenicity of Newcastle disease virus.
- Principal Investigator
  
  MIKAMI Takeshi
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  Applied veterinary science
- Research Institution
  The university of Tokyo
「ウイルス病原性の分子的基盤」研究推進のための調査研究Principal Investigator
- Principal Investigator
  
  永井美之
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  Virology
- Research Institution
  Nagoya University
抗エイズヌクレオシドの主作用、副作用の解析と予知並びに新設計のためのシステム開発Principal Investigator
- Principal Investigator
  
  永井美之
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Nagoya University
Studies on the Host Proteases which Determine Viral Spreading and Tropism.Principal Investigator
- Principal Investigator
  
  NAGAI Yoshiyuki
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  Nagoya University
Molecular Biology of Paramyxoviruses and the Viral PathogenesisPrincipal Investigator
- Principal Investigator
  
  NAGAI Yoshiyuki
- Project Period (FY)
  1985 – 1987
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  Virology
- Research Institution
  Nagoya University

All 2006 2005 2004 2003 2002 2001 Other

All Journal Article Book

[Book] In Biology of Negative Strand RNA Viruses, Y. Kawaoka(ed). Springer2004
- Author(s)
  Nagai Y., Kato, A
- Publisher
  Accessory genes of the paramyxoviridae, alarge family of nonsegmented negative-strand RNA viruses as a focus of active investigation by reverse genetics.
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Book] In virus Vectors, K. L. Hefferon(ed). Transworld Research Network.
- Author(s)
  Nagai Y., Inoue, M., Iida, A., Zhu Y-F., Hasegawa M., Kato A., Matsuno T.
- Publisher
  Sendai virus engineering : From reverse genetics to vector development.(in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] [Establishment and progress of Sendai virus engineering2006
- Author(s)
  Nagai Y, Kato A, Inoue M.
- Journal Title
  
  Tanpakushitsu Kakusan Koso 51(1)
  
  Pages: 27-37
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] [Establishment and progress of Sendai virus engineering2006
- Author(s)
  Nagai Y, Kato A, Inoue M.
- Journal Title
  
  tanpakushitsu Kakusan Koso 51(1)
  
  Pages: 27-37
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Establishment and progress of Sendai virus engineering2006
- Author(s)
  Nagai Y, Kato A, Inoue M.
- Journal Title
  
  Tanpakushitsu Kakusan Koso 51(1)
  
  Pages: 27-37
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Influence of glycosylation on the efficacy of an Env-based vaccine against simian immunodeficiency virus SIVmac239 in a macaque AIDS model.2005
- Author(s)
  Mori K, Sugimoto C, Ohgimoto S, Nakayama EE, Shioda T, Kusagawa S, Takebe Y, Kano M, Matano T, Yuasa T, Kitaguchi D, Miyazawa M, Takahashi Y, Yasunami M, Kimura A, Yamamoto N, Suzuki Y, Nagai Y
- Journal Title
  
  J. Virol. 79(16)
  
  Pages: 10386-10396
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Influence of glycosylation on the efficacy of an Env-based vaccine against simian immunodeficiency virus SIVmac239 in a macaque AIDS model2005
- Author(s)
  Mori K, Sugimoto C, Ohgimoto S, Nakayama EE, Shioda T Kusagawa S, Takebe Y, Kano M, Matano T, Yuasa T, Kitaguchi D Miyazawa M, Takahashi Y, Yasunami M, Kimura A, Yamamoto N Suzuki Y, Nagai Y.
- Journal Title
  
  J. Virol 79(16)
  
  Pages: 10386-10396
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] AIPI/Alix is a binding partner of Sendai virus C protein and facilitates virus budding.2005
- Author(s)
  Sakaguchi T, Kato A, Sugahara F, Shimazu Y, Inoue M, Kiyotani K, Nagai Y, Yoshida T.
- Journal Title
  
  J. virol. 79(14)
  
  Pages: 8933-8941
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] AIP1/Alix is a binding partner of Sendai virus C protein and facilitates virus budding.2005
- Author(s)
  Sakaguchi T, Kato A, Sugahara F, Shimazu Y, Inoue M, Kiyotani K, Nagai Y, Yoshida T.
- Journal Title
  
  J. Yirol. 79(14)
  
  Pages: 8933-8941
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Influence of glycosylation on the efficacy of an Env-based vaccine against aimian immunodeficiency virus SIVmac239 in a macaque AIDS model.2005
- Author(s)
  Mori K, Sugimoto C, Ohgimoto S, Nakayama EE, Shioda T, Kusagawa S, Takebe Y, Kano M, Matano T, Yuasa T, Kitaguchi D, Miyazawa M, Takahashi Y, Yasunami M, Kimura A, Yamamoto N, Suzuki Y, Nagai Y.
- Journal Title
  
  J.Virol. 79(16)
  
  Pages: 10386-10396
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] AIPI/Alix is a binding partner of Sendai virus C protein and facilitates virus budding.2005
- Author(s)
  Sakaguchi T, Kato A, Sugahara F, Shimizu Y, Inoue M, Kiyotani K, Nagai Y, Yoshida T.
- Journal Title
  
  J.Virol. 79(14)
  
  Pages: 8933-8941
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Accessory genes of the Paramyxoviridae, a large family of nonsegmented negative-strand RNA viruses, as a focus of active investigation by reverse genetics.2004
- Author(s)
  Nagai Y., Kato A.
- Journal Title
  
  Curr. Top. Microbiol. Immunol. 283
  
  Pages: 198-248
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Accessory genes of the paramyxoviridae, a large family of nonsegmented negative-strand RNA viruses, as focus of active investigation by reverse genetics.2004
- Author(s)
  Nagai Y, Kato A
- Journal Title
  
  Curr.Top.Microbial.Immunol. 283
  
  Pages: 197-248
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Accessory genes of the Paramyxoviridae, a large family of nonsegmented negative-strand RNA viruses, as a focus of active investigation by reverese genetics.2004
- Author(s)
  Nagai Y., Kato A.
- Journal Title
  
  Curr. Top. MicrobioL Immunol. 283
  
  Pages: 198-248
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Cytotoxic T Lymphocyte-based Control of Simian Immunodeficiency Virus Replication in a Preclinical AIDS Vaccine Trial.2004
- Author(s)
  Matano T, Kobayashi M, Igarashi H, Takeda A, Nakamura H, Kano M, Sugimoto C, Mori K, Iida A, Hirata T, Hasegawa M, Yuasa T, Miyazawa M, Takahashi Y, Yasunami M, Kimura A, O'Connor DH, Watkins DI, Nagai Y.
- Journal Title
  
  J Exp Med 199 (12)
  
  Pages: 1709-1718
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Cytotoxic T Lymphocyte-based Control of Simian Immunodeficiency Virus Replication in a Preclinical AIDS Vaccine Trial.2004
- Author(s)
  Matano T, Kobayashi M, Igarashi H, Takeda A, Nakamura H, Kano M, Sugimoto C, Mori K, Iida A, Hirata T, Hasegawa M, Yuasa T, Miyazawa M, Takahashi Y, Yasunami M, Kimura A, O'Connor DH, Watkins DI, Nagai Y.
- Journal Title
  
  J Exp Med 199(12)
  
  Pages: 1709-1718
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Cytotoxic T lymphocyte-based control of simian immunodeficiency virus replication in a preclinical AIDS vaccine trial.2004
- Author(s)
  Matano T, Kobayashi M, Igarashi H, Takeda A, Nakamura H, Kano M, Sugimoto C, Mori K, Iida A, Hirata T, Hasegawa M, Yuasa T, Miyazawa M, Takahashi Y, Yasunami M, Kimura A, O'Connor DH, Watkins DI, Nagai Y.
- Journal Title
  
  J.Exp.Med. 199(12)
  
  Pages: 1709-1718
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Accessory genes of the paramyxoviridae, a large family of nonsegmented negative-strand RNA viruses, as focus of active investigation by reverse genetics.2004
- Author(s)
  Kato A, Nagai Y
- Journal Title
  
  Curr Top Microbial Immunol 283
  
  Pages: 197-248
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Peotective efficacy of an AIDS vaccine, a single DNA priming followed by a single booster with a recombinant replication-defective Sendai virus vector, in a macaque AIDS model.2003
- Author(s)
  Takeda A, Igarashi H, Nakamura H, Kano M, Iida A, Hirata T, Hasegawa M, Nagai Y, Matano T.
- Journal Title
  
  J Virol. 77(17)
  
  Pages: 9710-9715
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] JNK-interacting protein 3 associates with Toll-like receptor 4 and is involved in LPS-mediated JNK activation2003
- Author(s)
  Matsuguchi T, Masuda A, Sugimoto K, Nagai Y, Yoshikai Y.
- Journal Title
  
  EMBO J. 22(17)
  
  Pages: 4455-4464
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] JNK-interacting protein 3 associates with Toll-like receptor 4 and is involved in LPS-mediated JNK activation.2003
- Author(s)
  Matsuguchi T, Masuda A, Sugimoto K, Nagai Y, Yoshikai Y.
- Journal Title
  
  EMBO J. 22(17)
  
  Pages: 4455-4464
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Protective efficacy of an AIDS vaccine, a single DNA primingfollowed by a single booster with a recombinant replication-defective Sendai virus vector, in a macaque AIDS model.2003
- Author(s)
  Takeda A, Igarashi H, Nakamura H, Kano M, Iida A, Hirata T, Hasegawa M, Nagai Y, Matano T.
- Journal Title
  
  J Virol. 77(17)
  
  Pages: 9710-9715
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Alteration of Sendai virus morphogenesis and nucleocapsid incorporation due to mutation of cysteine residues of the matrix protein.2002
- Author(s)
  Sakaguchi T, Uchiyama T, Huang C, Fukuhara N, Kiyotani K, Nagai Y, Yoshida T.
- Journal Title
  
  J Virol. 2002 Feb;76(4) : 1682-90.
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Fibroblast growth factor-2 determines severity of joint disease in adjuvant-induced arthritis in rats.2002
- Author(s)
  Yamashita A, Yonemitsu Y, Okano S, Nakagawa K, Nakashima Y, Irisa T, Iwamoto Y, Nagai Y, Hasegawa M, Sueishi K.
- Journal Title
  
  J Immunol. 168(1)
  
  Pages: 450-457
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Alteration of Sendai virus morphogenesis and nucleocapsid incorporation due to mutation of cysteine residues of the matrix protein.2002
- Author(s)
  Sakaguchi T, Uchiyama T, Huang C, Fukuhara N, Kiyotani K, Nagai Y, Yoshida T.
- Journal Title
  
  J Virol. 76(4)
  
  Pages: 1682-1690
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Naturally occurring deletional mutation in the C-terminal cytoplasmic tail of CCR5 affects surface trafficking of CCR5.2001
- Author(s)
  Shioda T, Nakayama EE, Tanaka Y, Xin X, Liu H, Kawana-Tachikawa A, Kato A, Sakai Y, Nagai Y, Iwamoto A
- Journal Title
  
  J Virol. 75(7)
  
  Pages: 3462-3468
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Quintuple deglycosylation mutant of simian immunodeficiency virus SIVmac239 in thesus macaques : robust primary replication, tightly contained chronic infection, and elicitation of potent immunity against the parental wild-rype strain.2001
- Author(s)
  Mori K, Yasutomi Y, Ohgimoto S, Nakasone T, Takamura S, Shioda T, Nagai Y.
- Journal Title
  
  J Virol. 75(9)
  
  Pages: 4023-4028
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Recembinant Sendai virus-mediated gene transfer to vasculature : a new class of efficient gene transfer vector to the vascular system.2001
- Author(s)
  Masaki I, Yonemitsu Y, Komori K, Ueno H, Nakashima Y, Nakagawa K, Fukumura M, Kato A, Hasan MK, Nagai Y, Sugimachi K, Hasegawa M, Sueishi K.
- Journal Title
  
  FASEB J. 15(7)
  
  Pages: 1294-1296
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Naturally occurring deletional mutation in the C-terminal cytoplasmic tail of CCR5 affects surface trafficking of CCR5.2001
- Author(s)
  Shioda T', Nakayama EE, Tanaka Y, Xin X, Liu H, Kawana-Tachikawa A, Kato A, Sakai Y, Nagai Y, Iwamoto A.
- Journal Title
  
  J Virol. 75(7)
  
  Pages: 3462-3468
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Rapid appearance of secondary immune responses and protection from acute CD4 depletion after a highly pathogenic immunodeficiency virus challenge in macaques vaccinated with a DNA prime/Senda virus vector boost regimen.2001
- Author(s)
  Matano T, Kano M, Nakamura H, Takeda A, Nagai Y.
- Journal Title
  
  J Virol. 75(23)
  
  Pages: 11891-11896
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Y2, the smallest of the Sendai virus C proteins, is fully capable of both cunteracting the antiviral action of interferons and inhibiting viral RNA synthesis.2001
- Author(s)
  Kato A, Ohnishi Y, Kohase M, Saito S, Tashiro M, Nagai Y.
- Journal Title
  
  J Virol. 75(8)
  
  Pages: 3802-10
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Recombinant Sendai virus-mediated gene transfer to vasculature: a new class of efficient gene transfer vector to the vascular system.2001
- Author(s)
  Masaki I, Yonemitsu Y, Komori K, Ueno H, Nakashima Y, Nakagawa K, Fukumura M, Kato A, Hasan MK, Nagai Y, Sugimachi K, Hasegawa M, Sueishi K.
- Journal Title
  
  FASEB J. 15(7)
  
  Pages: 1294-1296
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Augmentation of human immunodeficiency virus type 1 subtype E (CRF01_AE) multiple-drug resistance by insertion of a foreign 11-amino-acid fragment into the reverse transcriptase.2001
- Author(s)
  Sato H, Tomita Y, Ebisawa K, Hachiya A, Shibamura K, Shiino T, Yang R, Tatsumi M, Gushi K, Umeyama H, Oka S, Takabe Y, Nagai Y.
- Journal Title
  
  J Virol. 75(12)
  
  Pages: 5604-5613
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Rapid appearance of secondary immune responses and protection from acute CD4 depletion after a highly pathogenic immunodeficiency virus challenge in macaques vaccinated with a DNA prime/Sendai virus vector boost regimen.2001
- Author(s)
  Matano T, Kano M, Nakamura H, Takeda A, Nagai Y.
- Journal Title
  
  J Virol. 75(23)
  
  Pages: 11891-11896
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Y2, the smallest of the Sendai virus C proteins, is fully capable of both counteracting the antiviral action of interferons and inhibiting viral RNA synthesis.2001
- Author(s)
  Kato A, Ohnishi Y, Kohase M, Saito S, Tashiro M, Nagai Y.
- Journal Title
  
  J Virol. 75(8)
  
  Pages: 3802-10
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Augmentation of human immunodeficiency virus type 1 subtype E (CRFO1_AE) multiple-drug resistance by insertion of a foreign 11-amino-acid fragment into the reverse transcriptase.2001
- Author(s)
  Sato H, Tomita Y, Ebisawa K, Hachiya A, Shibamura K, Shiino T, Yang R, Tatsumi M, Gushi K, Umeyama H, Oka S, Takebe Y, Nagai Y.
- Journal Title
  
  J Virol. 75(12)
  
  Pages: 5604-5613
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13225001
[Journal Article] Quintuple deglycosylation mutant of simian immunodeficiency virus SIVmac239 in rhesus macaques : robust primary replication, tightly contained chronic infection, and elicitation of potent immunity against the parental wild-type strain.2001
- Author(s)
  Mori K, Yasutomi Y, Ohgimoto S, Nakasone T, Takamura S, Shioda T', Nagai Y.
- Journal Title
  
  J Virol. 75(9)
  
  Pages: 4023-4028
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13225001

1. UCHIYAMA Takashi (80151900)

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2. KATO Atsushi (40152699)

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NAGAI Yoshiyuki 永井 美之

永井 義之 ナガイ ヨシユキ

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Molecular Bases underlying Microbial Infections and the Host ResponsesPrincipal Investigator

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Basic Research for AIDS control A01 ; Host factors necessary for HIV-1 replicationPrincipal Investigator

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エイズの病態と制御に関する基礎研究 柱2.病態のウイルス学的基盤Principal Investigator

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Principal Investigator

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Gene manipulation of Sendai virus and development of Sendai virus vectorPrincipal Investigator

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Pathogenesis and Control of AIDSPrincipal Investigator

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エイズ研究の現状と展望Principal Investigator

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ウイルス病原性の分子的基盤Principal Investigator

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NAGAI Yoshiyuki 永井美之

永井義之ナガイヨシユキ

エイズの病態と制御に関する基礎研究柱2.病態のウイルス学的基盤Principal Investigator