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Narumiya Shuh  成宮 周

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NARUMIYA Shuh  成宮 周

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Researcher Number 70144350
Other IDs
Affiliation (Current) 2022: 京都大学, 医学研究科, 寄附講座教員
Affiliation (based on the past Project Information) *help 2017 – 2022: 京都大学, 医学研究科, 寄附講座教員
2016: 京都大学, 医学研究科, 教授
2012 – 2015: 京都大学, 医学(系)研究科(研究院), 教授
2013 – 2014: 京都大学, 医学(系)研究科(研究院), 教授(特任)
1995 – 2011: Kyoto University, Faculty of Medicine, Department of Pharmacology, Professor, 医学研究科, 教授 … More
2008: Kyoto University, 大学院・医学研究科, 教授
2006: 京大, 医学(系)研究科(研究院), 教授
2001: 京大, 医学(系)研究科(研究院), 教授
1999: 京都大学, 大学院・医学研究科, 教授
1996: Kyoto University Faculty of Medicine, Professor
1990 – 1996: Professor Department of Pharmacology Kyoto University Faculty of Medicine, 医学部, 教授
1987 – 1991: Department of Pharmacology, Faculty of Medicine, 医学部, 助教授
1986: 京大, 医学部, 助手
1986: 京都大学, 医学部, 助手
1985: 京都大学, 医, 助手 Less
Review Section/Research Field
Principal Investigator
General medical chemistry / General medical chemistry / Pathological medical chemistry / Biological Sciences / Medium-sized Section 48:Biomedical structure and function and related fields / 広領域 / 応用薬理学・医療系薬学 / General pharmacology
Except Principal Investigator
General pharmacology / 内分泌・代謝学 … More / Biological pharmacy / 代謝生物化学 / Pathological medical chemistry / Bioorganic chemistry / Structural biochemistry / Orthopaedic surgery / General medical chemistry Less
Keywords
Principal Investigator
細胞接着 / ADPリボシル化 / プロスタグランジン / Rho / mDia / GTP結合蛋白質 / 低分子量GTP結合蛋白質 / 細胞骨格 / アクチン / 受容体 … More / rho遺伝子産物 / 細胞質分裂 / アクチン細胞骨格 / ボツリヌス毒素 / 神経細胞 / トロンボキサン / インテグリン / 細胞運動 / 細胞移動 / rho遺伝子 / 神経突起 / 情報伝達 / ボツリヌスC_3酵素 / rho p21 / 微小管 / 細胞周期 / ROCK / 細胞内情報伝達 / 神経可塑性 / cell adhesion / p160ROCK / p140mDia / 脳 / rasがん遺伝子 / rho蛋白質 / ボツリヌス酵素 / GTPase活性化蛋白(GAP) / GTPase活性化蛋白質(GAP) / 細胞増殖 / ras類似蛋白質 / プロスタグランジンE受容体 / トロンボキサン受容体 / cDNAクロ-ニング / 遺伝子 / チロシンリン酸化 / プロスタグランジン受容体 / G蛋白質 / プロスタグランジンE / 細胞分裂 / 免疫 / がん化 / actin / cytokinesis / T細胞シグナリング / 精子形成 / シナプス / 細胞悪性化 / 培養細胞 / prostaglandin / 細胞接着斑 / アクチン重合 / microtubules / フィラグリン / 炎症 / ボツリヌス / 分化 / 脊髄神経節 / rho蛋白質(Gb) / 神経分化 / <rho>___ーがん遺伝子 / 遺伝子クロ-ニング / 細胞表現型 / rhoがん遺伝子 / アラキドン酸代謝物 / PCR / ロドプシン型受容体 / リゾホスファチジン酸 / PI3キナーゼ / rho-GAP / ウニ卵 / ボツリヌスC3酵素 / サイクリックAMP / EP_2受容体 / EP_3受容体 / トロンボキサン受容体遺伝子 / 痛み伝達 / 睡眠 / カチオン・チャネル / プロスタグランジンD / 蛋白質キナーゼ / 細胞内情報伝達系 / セリン スレオニン キナーゼ / 個体発生 / 癌化 / Rho GTPase / 癌 / Rho GTPases / ROCk / がん / 神経 / 遺伝子欠損マウス / 収縮環 / 核輸送 / Liprin / neuroepithelial polarity / neuronal migration / axon guidance / tissue architecture / 軸索ガイダンス / シナプス可塑性 / 組織恒常性 / 組織構築 / 恒常性 / 組織発生 / T細胞 / 皮膚腫瘍 / T 細胞 / 皮膚がん化 / TCRシグナリング / 腫瘍形成 / 増殖阻害作用 / 細胞内取り込み / 能動輸送系 / 血小板 / 作用機構 / プロスタグラジンE合成酵素 / グルタチオントランスフェラーゼ / ヒト脳 / アストログリア細胞 / 抗酵素抗体 / 免疫組織化学 / G_1期停止 / 蛋白合成 / 蛋白合成阻害剤 / 熱ショック蛋白 / 脳神経系 / GTP結合蛋白 / 神経細胞機能 / アメフラシ神経節 / ADPリボシル化反応 / ras発癌遺伝子 / 神経系 / 部分アミノ酸配列 / ボツリヌス菌体外酵素 / アクチンフィラメント / ras遺伝子 / Gb / botulinum exoenzyme / ADP-ribosylation / GTP binding protein / rho.gene product / cytoskeleton / actin filament / ras gene / 受容体リガンド結合 / 受容体アイソフォーム / 受容体遺伝子 / 体内分布 / トロンボキサン受容体異常症 / プロスタノイド受容体分子進化 / プロスタサイクリン受容体体内分布 / トロンボキサン受容体アイソフォーム / ラット脳EP_3受容体 / プロスタグランジン受容体遺伝子 / 血小板異常症 / 脳内分布 / アポプトーシス / 胸腺 / thromboxane receptor / ligand binding / signal transduction / receptor isoform / gene receptor / receptor distribution / receptor abnormality / rhop21 / PKN / P160^<ROCK> / 細胞形態変化 / SH_3 / focal adhesion / intergrin / actin polymerization / Neural plasticity / プロスタノイド / プロスタノイド受容体 / ノックアウトマウス / 遺伝子ノックアウトマウス / ES細胞 / C57BL / 6 / プロスタグラジン / トロンボキサンA_2 / prostanoid / thromboxane / prostanoid receptor / knockout mouse / 低分子量G蛋白質Rho / ROCKキナーゼ / ECT-2 / アクリン突起 / Pho / ストレス・ファイバー / LIMキナーゼ / コフィリン / 精子 / citronキナーゼ / がん浸潤 / 低分子量GTP結合蛋白質Rho / ROCK阻害薬 / Na-H交換体 / 蛋白質リン酸化酵素 / 低分子量G蛋白質 Rho / ストレス ファイバー / Small GTPase Rho / cell motility / ROCK kinase / Cdc42 / ミオシン / KOマウス / ROCK(Rho kinase) / 神経突起形成 / ROCK-II欠損マウス / 染色体分離 / Rac / citron-kinase / Actin / Cell motility / Cell cycle / 皮膚バリアー / アトピー性皮膚炎 / 角化細胞 / lysophosphatidic acid / Rhoシグナル / アリルハイドロカーボン受容体 / 創傷治癒 / LPA / Aryl Hydorcarbon受容体 / single cell RNA sequencing / 核内受容体 / 転写因子ネットワーク / アトピー / Aryl Hydrocarbon受容体 / 皮膚バリアー機能 / NHEK細胞 / リゾフォスファチジン酸(LPA) / SRF / 腫瘍微小環境 / プロスタグランジンE受容体EP2 / プロスタグランジンE受容体EP4 / 免疫細胞 / NFkB / 免疫抑制 / 制御性T細胞 / プロスタグランジンE2 / 腫瘍免疫回避 / 単一細胞RNA解析 / mregDC / がん免疫回避 / EP2/EP4受容体 / マウス担癌モデル / AhR / 皮膚角化細胞 / トリプトファン代謝 / CYP1A1 … More
Except Principal Investigator
プロスタグランジン / 動脈硬化 / 低分子量GTP結合蛋白質 / 平滑筋細胞 / HDL / 酸化LDL / Atherosclerosis / Oxidized LDL / シグナル伝達 / 受容体 / prostaglandin / receptor / マクロファ-ジ / LDL / 泡沫細胞 / マクロファージ / 酸化LDL受容体 / ICAM-1 / MCP-1 / Oxidized LDL receptor / 酵母 / ADPリボシル化 / ADP-ribosylation / ホスホリパーゼA_2 / 細胞接着 / Cell Adhesion / 15R-TIC / ノックアウトマウス / runt-related gene 2(runx2) / 低酸素 / 交感神経 / クロマフィン細胞 / カテコ-ルアミン / カルシウムイオン / ニコチン受容体 / カルシウムチャンネル / 一次求心性C線維 / 痛覚 / 受容体クローニング / ブラジキニン / ブロスタグランジン / オピオイド / 神経伝達物質 / 細胞内シグナル伝達 / 受容体クロ-ニング / PGE受容体 / EP_3サブタイプ / クローン化 / パッチクランブ / 背側縫線核 / in situハイブリダイゼーション法 / rho遺伝子産物 / 蛋白質キナーゼ / チロシンリン酸化 / 細胞質分裂 / 収縮環 / rho p21 / 細胞内情報伝達系 / セリン スレオニン キナーゼ / 細胞骨格 / 細胞運動 / 創薬 / 薬理学 / リバース薬理学 / ゲノム / 遺伝子 / 遺伝情報 / 機能解析 / 生命科学 / 脳血管スパスム / 内皮細依存性収縮 / 内皮細胞由来TX【A_2】様物質 / VOC / ROC / 脈動脈 / 受容体作動性Caチャンネル / アラキドン酸代謝 / リポキシゲナ-ゼ / レセプタ- / αリノレン酸 / 細胞情報伝達 / ロイコトリエン / αーリノレン酸 / α-リノレン酸 / arachidonic acid metabolism / lipoxygenase / alpha-linolenate / signal transduction / leukotriens / WHHLウサギ / リポタンパクリパ-ゼ / 血管内皮細胞 / WHHL rabbit / Smooth muscle cell / Macrophages / リゾフォスファチジルコリン / アポAーI / 酸化HDL / モノクロナ-ル抗体 / 粥状動脈硬化 / 家族性高コレステロ-ル血症 / Macrophage / Lyso-phosphatidyl-choline / 低分子量 / GTP結分蛋白質 / ボツリヌス毒素 / 哺乳類 / 分泌 / GTP結合蛋白質 / Low molecular weight / GTP-binding protein / Botulinum toxin / Yeast / Mammalian / Secretion / 細胞内小胞輸送 / リン酸化 / 情報伝達 / Small GTP-binding protein / Vesicle transport / Phosphorylation / Signal transduction / PAFアセチルハイドロラーゼ / P450(11β, aldo) / シクロオキシゲナーゼ / アルドステロン合成酵素 / PGE2受容体サブタイプ / 1α,25-(OH)2ビタミンD-24水酸化酵素 / ミッドカイン / PAF受容体 / P450(11β,aldo) / シクロオキシゲナーゼ-2(COX-2) / コルチコステロン合成酵素 / PGE_2受容体サブタイプ / 1α,25-(OH)_2ビタミンD-24水酸化酵素 / PAF受容体遺伝子 / アラキドン酸 / PAF / ステロイド産生 / レチノイン酸 / リポキシゲナーゼ / PAF acetylhydrolase / P450 (11beta, aldo) / cyclooxygenase / aldosterone synthetase / PGE2 receptor subtypes / 1alpha, 25-dihydroxyvitamin D3-24-hydroxylase / midkine / PAF receptor / 国際学術 / 海外派遣 / 癌 / 細胞社会学 / 細胞周期 / 薬品設計 / 遺伝子治療 / ウイルス発癌 / 癌治療 / 化学発癌 / 情報交換 / ドラッグデザイン / 癌遺伝子治療 / 癌化学療法 / 細胞増殖 / International Scientific Research / Cancer / Information Exchange / Signal Transduction / Cell Cycle / Drug Design / Gene Therapy / プロスタサイクリン / イソカルバサイクリン / 受容体探索子 / APNIC / 受容体タンパク質 / クローニング / Prostacyclin / Isocarbacyclin / Receptor / 脂質メディエーター / プロテインキナーゼC / ホスホリパーゼ / 血小板活性化因子 / 低分子量Gタンパク / 無脳回症 / 開口放出 / Miller-Dieker / グリア細胞 / プロスタノイド / 神経可塑性 / 低分子量Gタンパク質 / lipid mediators / protein kinase C / phospholipases / インテグリン / 細胞外マトリックス / パキシリン / カドヘリン / ラミニン / 膜結合型増殖因子 / 細胞内骨格系 / Rho / HB-EGF / Integrin / Extracellular Matrix / PAxillin / Cadherin / Smooth Moscle Cells / Laminin / Membrane-bound Cell Growth Factor / アゴンスト / 骨形成 / core-binding factor α1(cbfal) / 骨形態計測 / 選択的アゴニスト / core binding factorα1 (cbfal) / Bone morphogenetic protein (BMP) / マイクロレイ / Core binding factor α1(Cbta1) / Bone morphogenetic protein(BMP) / マイクロアレイ / knockout mouse / agonist / bone formation / core-binding factor α1 / histomorphometry / 脳血管〓縮物質 / 内皮細胞由来血管収縮物質 / TXA2-様物質 / 脳血管攣縮 / クモ膜下出血 / 内皮細胞依存性収縮因子 / TX【A_2】様物質 / 脳脊髄液 / 脳血管 / 内皮細胞 / Subarachnoid hemorrhage / Cerebrospinal fluid / Endothelium-dependent contraction / 家族性高コレステロール血症 / プロスタグランディン / リポタンパク / コレステロール / Familial Hypercholesterolemia / Prostaglandin,Lipoprotein / 酸化LDL受容性 / 抗酸化剤 / 泡洙細胞 / 修飾LDL / スーパーオキサイド / Antioxidant / Foam cell Less
  • Research Projects

    (58 results)
  • Research Products

    (180 results)
  • Co-Researchers

    (188 People)
  •  Identification of an endogenous AhR ligand and charcetrization of its mode of actionPrincipal Investigator

    • Principal Investigator
      成宮 周
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 48:Biomedical structure and function and related fields
    • Research Institution
      Kyoto University
  •  Prostaglandin-mediated cancer immunoevasion; identification of target cell populations and elucidation of their mechanismsPrincipal Investigator

    • Principal Investigator
      成宮 周
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 48:Biomedical structure and function and related fields
    • Research Institution
      Kyoto University
  •  Molecular pharmacological analysis of skin barrier regulatory mechanismsPrincipal Investigator

    • Principal Investigator
      narumiya shuh
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      General pharmacology
    • Research Institution
      Kyoto University
  •  Physiological roles and action mechanisms of mDia-induced actin cytoskeleton in the bodyPrincipal Investigator

    • Principal Investigator
      Narumiya Shuh
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      General medical chemistry
    • Research Institution
      Kyoto University
  •  mDiaが紡ぐアクチン細胞骨格の個体生理での役割と分子メカニズムの解析Principal Investigator

    • Principal Investigator
      成宮 周
    • Project Period (FY)
      2014
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      General medical chemistry
    • Research Institution
      Kyoto University
  •  The role of Rho-mDia siganling in tissue architecture and homeostasis in the bodyPrincipal Investigator

    • Principal Investigator
      NARUMIYA Shuh
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      General medical chemistry
    • Research Institution
      Kyoto University
  •  個体での組織構築・恒常性におけるRho-mDia経路の役割Principal Investigator

    • Principal Investigator
      成宮 周
    • Project Period (FY)
      2011
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      General medical chemistry
    • Research Institution
      Kyoto University
  •  Spatiotemporal control of cell functions by Rho GTPases ; mechanisms and physiological rolesPrincipal Investigator

    • Principal Investigator
      NARUMIYA Shuh
    • Project Period (FY)
      2006 – 2010
    • Research Category
      Grant-in-Aid for Specially Promoted Research
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  Rho GTPasesを介する細胞機能の時空間特異的制御と個体での役割Principal Investigator

    • Principal Investigator
      成宮 周
    • Project Period (FY)
      2006
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      General medical chemistry
    • Research Institution
      Kyoto University
  •  低分子量G蛋白質Rhoの情報伝達と生理的意義の研究Principal Investigator

    • Principal Investigator
      成宮 周
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      General medical chemistry
    • Research Institution
      Kyoto University
  •  プロスタノイド受容体の病態的意義と創薬科学的研究Principal Investigator

    • Principal Investigator
      成宮 周
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      広領域
    • Research Institution
      Kyoto University
  •  Signal Transduction and Biological Significance of the Small GTPase RhoPrincipal Investigator

    • Principal Investigator
      NARUMIYA Shuh
    • Project Period (FY)
      2001 – 2005
    • Research Category
      Grant-in-Aid for Specially Promoted Research
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  Analyses of bones of prostanoid receptor-deficient mice

    • Principal Investigator
      MATSUSHITA Mutsumi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      KYOTO UNIVERSITY
  •  リバース薬理学の展開

    • Principal Investigator
      三品 昌美
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      The University of Tokyo
  •  Signal Transduction and Cellular Functions of the Small GTPase Rho and its EffectorsPrincipal Investigator

    • Principal Investigator
      NARUMIYA Shuh
    • Project Period (FY)
      1996 – 2000
    • Research Category
      Grant-in-Aid for Specially Promoted Research
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  細胞質分裂におけるrho遺伝子産物の機能

    • Principal Investigator
      斉藤 雄二
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  rho p21の情報伝達経路とその転移、浸潤における役割の解明Principal Investigator

    • Principal Investigator
      成宮 周
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  rho p21 in Neural Development and PlasticityPrincipal Investigator

    • Principal Investigator
      KAKIZUKA Akira, 成宮 周
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      KYOTO UNIVERSITY
  •  Molecular mechanism of synaptic plasticity

    • Principal Investigator
      SHIMIZU Takao
    • Project Period (FY)
      1995 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  Role of Integrin-mediated Signal Transduction in Cell Growth and Differentiation

    • Principal Investigator
      SEKIGUCHI Kiyotoshi
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Structural biochemistry
    • Research Institution
      Research Institute, Osaka Medical Center for Maternal and Child Health
  •  Generation and analysis of mice lacking the prostanoid receptorPrincipal Investigator

    • Principal Investigator
      USHIKUBI Fumitaka, 成宮 周
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      KYOTO UNIVERSITY
  •  中枢シナプスにおけるプロスタグランジンE受容体サブタイプの構造と機能の解析Principal Investigator

    • Principal Investigator
      成宮 周
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  細胞質分裂におけるrho遺伝子産物の機能

    • Principal Investigator
      森井 成人
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  rho遺伝子産物の細胞内機能とがん細胞形質発現における役割Principal Investigator

    • Principal Investigator
      成宮 周
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  Information Exchange on Cancer Research with North American

    • Principal Investigator
      YAMAMOTO Tadashi
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      The University of Tokyo
  •  Design of specific Molecular Probes for a Prostacyclin Receptor

    • Principal Investigator
      SUZUKI Masaaki
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Bioorganic chemistry
    • Research Institution
      Gifu University
  •  rhoがん遺伝子産物の機能とこれを介する情報伝達経路の研究Principal Investigator

    • Principal Investigator
      成宮 周
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  中枢シナプスにおけるプロスタグランジンE受容体EP_3サブタイプの分布と機能の解析

    • Principal Investigator
      MOMIYAMA Toshihiko
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  Action mechanisms and roles of small GTP-binding proteins

    • Principal Investigator
      NOZAWA Yoshinori
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Gifu University
  •  A study for gene expression of synthetic enzymes and receptors for lipid biofactors

    • Principal Investigator
      ICHIKAWA Atsushi
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      KYOTO UNIVERSITY
  •  Structures and functions of the Prostanoid ReceptorsPrincipal Investigator

    • Principal Investigator
      NARUMIYA Shuh
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      KYOTO UNIVERSITY
  •  血管内皮及び平滑筋プロスタグランジン受容体とこれを介する収縮弛緩機構の研究Principal Investigator

    • Principal Investigator
      成宮 周
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  プロスタグランジン受容体の分子構造と機能の研究Principal Investigator

    • Principal Investigator
      成宮 周
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Kyoto University
  •  rhoがん遺伝子産物の機能とこれを介する情報伝達経路の研究Principal Investigator

    • Principal Investigator
      成宮 周
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  血管内皮及び平滑筋プロスタグランジン受容体とこれを介する収縮弛緩機構の研究Principal Investigator

    • Principal Investigator
      成宮 周
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  プロスタグランジン受容体の分子構造と機能の研究Principal Investigator

    • Principal Investigator
      成宮 周
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Kyoto University
  •  一次求心性C線維の神経回路と機能的意義

    • Principal Investigator
      熊澤 孝朗
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Nagoya University
  •  Studies on the conformation and functions of ras-related low Mr GTP-binding proteins.

    • Principal Investigator
      NOZAWA Yoshinori
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      代謝生物化学
    • Research Institution
      Gifu University
  •  ボツリヌス菌由来のADPリボシル化酵素による神経突起誘導の分子機構の解析Principal Investigator

    • Principal Investigator
      成宮 周
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  脳の老化やアルツハイマ-病変における低分子量GTP結合蛋白質Gbの役割Principal Investigator

    • Principal Investigator
      成宮 周
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  rhoがん遺伝子産物の機能とこれを介する情報伝達経路の研究Principal Investigator

    • Principal Investigator
      成宮 周
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  Studies on the initiation of atherosclerosis

    • Principal Investigator
      KITA Toru
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      KYOTO UNIVERSITY
  •  低酸素環境下における血管系の神経情報変換・伝達機構

    • Principal Investigator
      FUJIWARA Motohatsu
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      Kyoto University
  •  ボツリヌス神経毒素による新しいGTP結合蛋白の発見とその生理機能の解析Principal Investigator

    • Principal Investigator
      成宮 周
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  脳の老化やアルツハイマ-病変における低分子量GTP結合蛋白質Gbの役割Principal Investigator

    • Principal Investigator
      成宮 周
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  Signal Transduction and Arachidonic Acid Metabolism in the Aid Drug of Development

    • Principal Investigator
      ICHIKAWA Atsushi
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kyoto University
  •  Study for the pathogenesis of atherosclerosis.

    • Principal Investigator
      KITA Toru
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      内分泌・代謝学
    • Research Institution
      Kyoto University
  •  Botulinum ADP-ribosyltransferase and its substrate, Gb.Principal Investigator

    • Principal Investigator
      NARUMIYA Shuh
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      KYOTO UNIVERSITY
  •  神経終末に存在するボツリヌス神経毒素標的蛋白の検出とシナプス機能に於ける役割の解明Principal Investigator

    • Principal Investigator
      成宮 周
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  ボツリヌス神経毒素による新しいGTP結合蛋白の発見とその生理機能の解析Principal Investigator

    • Principal Investigator
      成宮 周
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  Study for the mechanism of LDL modification search for its inhibitor.

    • Principal Investigator
      KITA Toru
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for Developmental Scientific Research
    • Research Field
      General medical chemistry
    • Research Institution
      KYOTO UNIVERSITY
  •  血管スパスムにおけるCaイオン動態と役割:受容体作動性Caイオンチャンネル

    • Principal Investigator
      藤原 元始
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      Kyoto University
  •  プロスタグランジンの細胞内取り込みと作用発現機構の研究Principal Investigator

    • Principal Investigator
      成宮 周
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Kyoto University
  •  ヒト脳血管スパスムにおけるCaイオンの動態と役割

    • Principal Investigator
      藤原 元始
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      Kyoto University
  •  ヒト脳よりのプロスタグランジンE合成酵素の精製とそれに対する抗体の作製Principal Investigator

    • Principal Investigator
      成宮 周
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Kyoto University
  •  Study for the initial event of athcrosclerosis.

    • Principal Investigator
      KITA Toru
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      内分泌・代謝学
    • Research Institution
      Kyoto University
  •  興奮性細胞膜でのプロスタグランジン作用の発現メカニズムの研究Principal Investigator

    • Principal Investigator
      成宮 周
    • Project Period (FY)
      1985
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      Kyoto University
  •  Expoloration of spasmogenic factors and its antagonist for cerebrovasculor spasm

    • Principal Investigator
      FUJIWARA Motohatsu
    • Project Period (FY)
      1985 – 1987
    • Research Category
      Grant-in-Aid for Developmental Scientific Research
    • Research Field
      General pharmacology
    • Research Institution
      Kyoto University

All 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 Other

All Journal Article Presentation Book

  • [Book] Molecular structures, cellular functions, and physiological roles of Rho effectors in Ras Superfamily Small G Proteins: Biology and Mechanisms (ed. Alfred Wittinghofer)2014

    • Author(s)
      Ishizaki T and Narumiya S
    • Total Pages
      742
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-26221302
  • [Book] Molecular Structures, Cellular Functions and Physiological Roles of Rho Effectors in Ras superfamily small G proteins : Biology and Mechanisms (Wittinghofer, A., ed.)

    • Author(s)
      Ishizaki T., Narumiya, S
    • Publisher
      Springer(in press)
    • Data Source
      KAKENHI-PROJECT-23229003
  • [Journal Article] PGE2-EP2/EP4 signaling elicits immunosuppression by driving the mregDC-Treg axis in inflammatory tumor microenvironment2022

    • Author(s)
      Dean Thumkeo, Siwakorn Punyawatthananukool, Somsak Prasongtanakij, Ryuma Matsuura, Kentaro Arima, Huan,Nie, Rie Yamamoto, Naohiro Aoyama, Hisao Hamaguchi, Shingo Sugahara, Shinobu Takeda, Varodom Charoensawan, Atsushi Tanaka, Shimon Sakaguchi, Shuh Narumiya
    • Journal Title

      Cell Reports

      Volume: accepted

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H00498
  • [Journal Article] Single-cell RNA sequencing identifies a migratory keratinocyte subpopulation expressing THBS1 in epidermal wound healing2022

    • Author(s)
      Siriwach Ratklao、Ngo Anh Quynh、Higuchi Makio、Arima Kentaro、Sakamoto Satoko、Watanabe Akira、Narumiya Shuh、Thumkeo Dean
    • Journal Title

      iScience

      Volume: 25 Pages: 104130-104130

    • DOI

      10.1016/j.isci.2022.104130

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H00498, KAKENHI-PROJECT-20K07287
  • [Journal Article] mDia1/3-dependent actin polymerization spatiotemporally controls LAT phosphorylation by Zap70 at the immune synapse2020

    • Author(s)
      Thumkeo, D., Katsura, Y., Nishimura, Y., Kanchanawong, P., Tohyama, K., Ishizaki, T., Kitajima, S., Takahashi, C., Hirata, T., Watanabe, N., Krummel, M. F., and Narumiya, S.
    • Journal Title

      Sci Adv

      Volume: 6 Pages: 2432-2432

    • DOI

      10.1126/sciadv.aay2432

    • NAID

      120006777011

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07621, KAKENHI-PROJECT-19K22555, KAKENHI-PROJECT-17H01531, KAKENHI-PROJECT-17H03576, KAKENHI-PROJECT-17K08339, KAKENHI-PROJECT-17K08591, KAKENHI-PROJECT-19H01020, KAKENHI-PROJECT-20H03509
  • [Journal Article] T cell-intrinsic prostaglandin E2-EP2/EP4 signaling is critical in pathogenic TH17 cell-driven inflammation.2019

    • Author(s)
      Lee J, Aoki T, Thumkeo D, Siriwach R, Yao C, Narumiya S.
    • Journal Title

      J Allergy Clin Immunol.

      Volume: 143(2) Pages: 631-643

    • DOI

      10.1016/j.jaci.2018.05.036

    • NAID

      120006557522

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H01531, KAKENHI-PROJECT-17K08591
  • [Journal Article] LPA Induces Keratinocyte Differentiation and Promotes Skin Barrier Function through the LPAR1/LPAR5-RHO-ROCK-SRF Axis2019

    • Author(s)
      Sumitomo A, Siriwach R, Thumkeo D, Ito K, Nakagawa R, Tanaka N, Tanabe K, Watanabe A, Kishibe M, Ishida-Yamamoto A, Honda T, Kabashima K, Aoki J, Narumiya S.
    • Journal Title

      J Invest Dermatol

      Volume: pii: S0022-202X(18)32815-X. Pages: 1010-1022

    • DOI

      10.1016/j.jid.2018.10.034

    • NAID

      120006630981

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H01531, KAKENHI-PROJECT-17K08591
  • [Journal Article] Ligand binding to human prostaglandin E receptor EP4 at the lipid-bilayer interface.2019

    • Author(s)
      Toyoda Y, Morimoto K, Suno R, et al.
    • Journal Title

      Nature chemical biology

      Volume: 15 Pages: 18-26

    • DOI

      10.1038/s41589-018-0131-3

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K05334, KAKENHI-PROJECT-18K14904, KAKENHI-PLANNED-15H05905, KAKENHI-PLANNED-17H06414, KAKENHI-PROJECT-17H01531, KAKENHI-PROJECT-17H03663, KAKENHI-PROJECT-17H03990, KAKENHI-PROJECT-19K22503, KAKENHI-PROJECT-19K16354, KAKENHI-ORGANIZER-15H05897, KAKENHI-PROJECT-19H00923, KAKENHI-PLANNED-19H05777
  • [Journal Article] Prostaglandin-cytokine crosstalk in chronic inflammation.2019

    • Author(s)
      Yao C, Narumiya S.
    • Journal Title

      Br J Pharmacol.

      Volume: 176(3). Pages: 337-354

    • DOI

      10.1111/bph.14530

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H01531
  • [Journal Article] Inhibition of microsomal prostaglandin E synthase-1 facilitates liver repair after hepatic injury in mice2019

    • Author(s)
      Nishizawa N, Ito Y, Eshima K, Ohkubo H, Kojo K, Inoue T, Raouf J, Jakobsson PJ, Uematsu S, Akira S, Narumiya S, Watanabe M, Majima M.
    • Journal Title

      J Hepatol

      Volume: S0168-8278(18) Pages: 110-120

    • DOI

      10.1016/j.jhep.2018.02.009

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293055, KAKENHI-PROJECT-17H01531, KAKENHI-PROJECT-16K21350, KAKENHI-PROJECT-18K15760, KAKENHI-PROJECT-18K16330, KAKENHI-PROJECT-18K16373, KAKENHI-PROJECT-17H04257, KAKENHI-PROJECT-18H02571, KAKENHI-PROJECT-18H02605, KAKENHI-PROJECT-16K10581, KAKENHI-PROJECT-17K19543
  • [Journal Article] Crystal structure of the endogenous agonist-bound prostanoid receptor EP32019

    • Author(s)
      Morimoto K, Suno R, Hotta Y, Yamashita K, Hirata K, Yamamoto M, Narumiya S, Iwata S, Kobayashi T.
    • Journal Title

      Nature Chemical Biology

      Volume: 15(1) Pages: 8-10

    • DOI

      10.1038/s41589-018-0171-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H01531, KAKENHI-PROJECT-19H00923, KAKENHI-PLANNED-19H05777
  • [Journal Article] MAFB is dispensable for the fetal testis morphogenesis and the maintenance of spermatogenesis in adult mice.2018

    • Author(s)
      S. Sakamoto, D. Thumkeo, H. Ohta, Z. Zhang, S.R. Huang, P. Kanchenawong, T. Fuu, S. Watanabe, K. Shimada, Y. Fujihara, S. Yoshida, M. Ikawa, N. Watanabe, M. Saitou and S. Narumiya
    • Journal Title

      PLoS Biol

      Volume: 16

    • DOI

      10.1371/journal.pbio.2004874

    • NAID

      120006531249

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-18H05551, KAKENHI-PROJECT-16H02507, KAKENHI-PROJECT-17H01531, KAKENHI-PROJECT-15H05573, KAKENHI-PROJECT-17H06098, KAKENHI-PROJECT-17K08591
  • [Journal Article] The Innate Immune Receptors TLR2/4 Mediate Repeated Social Defeat Stress-Induced Social Avoidance through Prefrontal Microglial Activation.2018

    • Author(s)
      Nie Xiang、Kitaoka Shiho、Tanaka Kohei、Segi-Nishida Eri、Imoto Yuki、Ogawa Atsubumi、Nakano Fumitake、Tomohiro Ayaka、Nakayama Kazuki、Taniguchi Masayuki、Mimori-Kiyosue Yuko、Kakizuka Akira、Narumiya Shuh、Furuyashiki Tomoyuki
    • Journal Title

      Neuron

      Volume: 99 Pages: 464-479

    • DOI

      10.1016/j.neuron.2018.06.035

    • NAID

      120006541943

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08316, KAKENHI-PROJECT-17K08593, KAKENHI-PUBLICLY-17H05572, KAKENHI-PUBLICLY-17H06057, KAKENHI-PROJECT-17H01531, KAKENHI-PROJECT-16H05132, KAKENHI-PROJECT-17J09360, KAKENHI-PROJECT-17K19457, KAKENHI-PROJECT-20K20379, KAKENHI-PROJECT-16H05151
  • [Journal Article] Rho signaling research: history, current status and future directions.2018

    • Author(s)
      Narumiya S, Thumkeo D.
    • Journal Title

      FEBS Lett.

      Volume: 592(11) Pages: 1763-1776

    • DOI

      10.1002/1873-3468.13087

    • NAID

      120006491996

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H01531
  • [Journal Article] Thromboxane A 2 facilitates IL-17A production from Vγ4 + γδ T cells and promotes psoriatic dermatitis in mice2018

    • Author(s)
      Ueharaguchi Y, Honda T, Kusuba N, Hanakawa S, Adachi A, Sawada Y, Otsuka A, Kitoh A, Dainich T, Egawa G, Nakachima C, Nakajima S, Murata T, Ono S, Arita M, Narumiya S, Miyachi Y, Kabashima K
    • Journal Title

      J Allergy Clin Immunol.

      Volume: in press

    • DOI

      10.1016/j.jaci.2018.01.054

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09766, KAKENHI-ORGANIZER-15H05897, KAKENHI-PROJECT-17K19655, KAKENHI-PLANNED-15H05898, KAKENHI-PROJECT-17H01531
  • [Journal Article] Dopamine D1 receptor subtype mediates acute stress-induced dendritic growth in excitatory neurons of the medial prefrontal cortex and contributes to suppression of stress susceptibility in mice.2018

    • Author(s)
      Shinohara R, Taniguchi M, Ehrlich AT, Yokogawa K, Deguchi Y, Cherasse Y, Lazarus M, Urade Y, Ogawa A, Kitaoka S, Sawa A, Narumiya S, *Furuyashiki T.
    • Journal Title

      Mol. Psychiatry

      Volume: -

    • DOI

      10.1038/mp.2017.177

    • NAID

      120006599256

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08593, KAKENHI-PROJECT-17K19457, KAKENHI-PUBLICLY-17H05572, KAKENHI-PUBLICLY-17H06057, KAKENHI-PROJECT-17H01531, KAKENHI-PROJECT-16H05132, KAKENHI-PROJECT-17J09360, KAKENHI-PROJECT-16K18365, KAKENHI-PROJECT-16H01881
  • [Journal Article] Prostaglandin E 2 stimulates adaptive IL-22 production and promotes allergic contact dermatitis2018

    • Author(s)
      Robb Calum T.、McSorley Henry J.、Lee Jinju、Aoki Tomohiro、Yu Cunjing、Crittenden Siobhan、Astier Anne、Felton Jennifer M.、Parkinson Nicholas、Ayele Adane、Breyer Richard M.、Anderton Stephen M.、Narumiya Shuh、Rossi Adriano G.、Howie Sarah E.、Guttman-Yassky Emma、Weller Richard B.、Yao Chengcan
    • Journal Title

      Journal of Allergy and Clinical Immunology

      Volume: 141 Pages: 152-162

    • DOI

      10.1016/j.jaci.2017.04.045

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H01531
  • [Journal Article] Constitutive Activation of Integrin α9 Augments Self-Directed Hyperplastic and Proinflammatory Properties of Fibroblast-like Synoviocytes of Rheumatoid Arthritis2017

    • Author(s)
      Emori Takashi、Hirose Jun、Ise Kotoko、Yomoda Jun-ichiro、Kasahara Michiko、Shinkuma Tadanobu、Yoshitomi Hiroyuki、Ito Hiromu、Hashimoto Motomu、Sugahara Shingo、Fujita Hirotada、Yamamoto Nobuchika、Morita Yoshiaki、Narumiya Shuh、Aramori Ichiro
    • Journal Title

      The Journal of Immunology

      Volume: 199 Pages: 3427-3436

    • DOI

      10.4049/jimmunol.1700941

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H01531
  • [Journal Article] Macrophage imaging of cerebral aneurysms with ferumoxytol2017

    • Author(s)
      Aoki Tomohiro、Saito Makoto、Koseki Hirokazu、Tsuji Keiichi、Tsuji Atsushi、Murata Kiyoshi、Kasuya Hidetoshi、Morita Akio、Narumiya Shuh、Nozaki Kazuhiko
    • Journal Title

      J Stroke Cerebrovasc Dis

      Volume: 26 Pages: 20552064-20552064

    • DOI

      10.1016/j.jstrokecerebrovasdis.2016.10.026

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H01531, KAKENHI-PROJECT-15H04949, KAKENHI-PROJECT-15K10316
  • [Journal Article] A S1P1 agonist, ASP4058, suppresses intracranial aneurysm through promoting2017

    • Author(s)
      Yamamoto Rie、Aoki Tomohiro、Koseki Hirokazu、Fukuda Miyuki、Hirose Jun、Tsuji Keiichi、Takizawa Katsumi、Nakamura Shinichiro、Miyata Haruka、Hamakawa Nozomu、Kasuya Hidetoshi、Nozaki Kazuhiko、Hirayama Yoshitaka、Aramori Ichiro、Narumiya Shuh
    • Journal Title

      Br J Pharmacol

      Volume: 174 Pages: 2085-2101

    • DOI

      10.1111/bph.13820

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H01531, KAKENHI-PROJECT-15H04949
  • [Journal Article] Targeting macrophages to treat intracranial aneurysm2017

    • Author(s)
      Aoki T., Yamamoto R., Narumiya S.
    • Journal Title

      Oncotarget

      Volume: 28 Pages: 104704-104705

    • DOI

      10.18632/oncotarget.21368

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10719, KAKENHI-PROJECT-17H01531
  • [Journal Article] Gut microbiota promotes obesity-associated liver cancer throug PGE2-mediated suppression of antitumor immunity2017

    • Author(s)
      Loo TM, Kamachi F, Watanabe Y, Yoshimoto S, Kanda H, Arai Y, Nakajima-Takagi Y, Iwama A, Koga T, Sugimoto Y, Ozawa T, Nakamura M, Kumagai M, Watashi K, Taketo MM, Aoki T, Narumiya S, Oshima M, Arita M, Hara E, Ohtani N
    • Journal Title

      Cancer Discovery

      Volume: in press Pages: 522-538

    • DOI

      10.1158/2159-8290.cd-16-0932

    • Description
      Epub ahead of print
    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05898, KAKENHI-PLANNED-15H05905, KAKENHI-PROJECT-26250028, KAKENHI-PROJECT-14J06998, KAKENHI-PROJECT-15K12709, KAKENHI-PROJECT-15K19032, KAKENHI-PROJECT-26670030, KAKENHI-PROJECT-15K19031, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-17H01531, KAKENHI-PROJECT-15H04648, KAKENHI-PROJECT-17H03990, KAKENHI-PROJECT-26460565, KAKENHI-PROJECT-16H04699
  • [Journal Article] Virus-induced inflammasome activation is suppressed by prostaglandin D2/DP1 signaling2017

    • Author(s)
      Vijay Rahul、Fehr Anthony R.、Janowski Ann M.、Athmer Jeremiah、Wheeler Dorthea L.、Grunewald Matthew、Sompallae Ramakrishna、Kurup Samarchith P.、Meyerholz David K.、Sutterwala Fayyaz S.、Narumiya Shuh、Perlman Stanley
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 114

    • DOI

      10.1073/pnas.1704099114

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H01531
  • [Journal Article] T cell function is dispensable for intracranial aneurysm formation and progression2017

    • Author(s)
      Miyata H., Koseki H., Takizawa K., Kasuya H., Nozaki K., Narumiya S., Aoki T.
    • Journal Title

      PLoS One

      Volume: 12

    • DOI

      10.1371/journal.pone.0175421

    • NAID

      120006309300

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10719, KAKENHI-PROJECT-17H01531, KAKENHI-PROJECT-15H04949, KAKENHI-PROJECT-15K10316
  • [Journal Article] Exacerbation of Aging-Associated and Instability-Induced Murine Osteoarthritis With Deletion of D Prostanoid Receptor 1, a Prostaglandin D2 Receptor2017

    • Author(s)
      Ouhaddi Yassine、Nebbaki Sarah-Salwa、Habouri Lauris、Afif Hassan、Lussier Bertrand、Kapoor Mohit、Narumiya Shuh、Pelletier Jean-Pierre、Martel-Pelletier Johanne、Benderdour Mohamed、Fahmi Hassan
    • Journal Title

      Arthritis & Rheumatology

      Volume: 69 Pages: 1784-1795

    • DOI

      10.1002/art.40160

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H01531
  • [Journal Article] mDia and ROCK Mediate Actin-Dependent Presynaptic Remodeling Regulating Synaptic Efficacy and Anxiety2016

    • Author(s)
      Deguchi Y, Harada M, Shinohara R, Lazarus M, Cherasse Y, Urade Y, Yamada D, Sekiguchi M, Watanabe D, Furuyashiki T, Narumiya S.
    • Journal Title

      Cell Rep.

      Volume: 17 Pages: 24052417-24052417

    • DOI

      10.1016/j.celrep.2016.10.088

    • NAID

      120005868496

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PUBLICLY-15H01289, KAKENHI-PLANNED-26112007, KAKENHI-PROJECT-24220009, KAKENHI-PROJECT-26221302, KAKENHI-PROJECT-16H05132, KAKENHI-PROJECT-15K14315, KAKENHI-PROJECT-16K18365, KAKENHI-PROJECT-16H01881
  • [Journal Article] Citron kinase mediates transition from constriction to abscission through its coiled-coil domain.2013

    • Author(s)
      Watanabe S, De Zan T, Ishizaki T, Narumiya S.
    • Journal Title

      J. Cell Sci

      Volume: (印刷中(in press) Pages: 1773-1784

    • DOI

      10.1242/jcs.116608

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J04389, KAKENHI-PROJECT-22501011, KAKENHI-PROJECT-23229003, KAKENHI-PUBLICLY-25121714, KAKENHI-PROJECT-25430109, KAKENHI-PUBLICLY-23121514
  • [Journal Article] Physiological roles of Rho and Rho effectors in mammals.2013

    • Author(s)
      Thumkeo D, Watanabe S, Narumiya S
    • Journal Title

      European Journal of Cell Biology

      Volume: Vol.92, 10-11 Pages: 303-315

    • DOI

      10.1016/j.ejcb.2013.09.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J04389, KAKENHI-PROJECT-23229003, KAKENHI-PROJECT-25860188
  • [Journal Article] Loss of a Rho-Regulated Actin Nucleator, mDia2, Impairs Cytokinesis during Mouse Fetal Erythropoiesis2013

    • Author(s)
      Watanabe S, De Zan T, Ishizalki T, Yasuda S, Kamijo H, Yamada D, Aoki T, Kiyonari H, Kaneko H, Shimizu R, Yamamoto M, Goshima G, and, Narummiya S
    • Journal Title

      Cell Report

      Volume: 5(4) Pages: 926-932

    • DOI

      10.1016/j.celrep.2013.10.021

    • NAID

      120005347116

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J04389, KAKENHI-PROJECT-23229003, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24659142, KAKENHI-PROJECT-24659456, KAKENHI-PUBLICLY-25121714
  • [Journal Article] F/G-actin homeostasis regulates mechanosensitive actin nucleation by formins.2013

    • Author(s)
      Higashida C, Kiuchi T, Akiba Y, Mizuno H, Maruoka M, Narumiya S, Mizuno K, Watanabe N
    • Journal Title

      Nat. Cell Biol

      Volume: 15(4) Pages: 395-405

    • DOI

      10.1038/ncb2693

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23229003, KAKENHI-PROJECT-24370051, KAKENHI-PROJECT-24770146, KAKENHI-PROJECT-24770175, KAKENHI-PUBLICLY-24121702
  • [Journal Article] Moesin controls clathrin-mediated S1PR1 internalization in T cells2013

    • Author(s)
      Nomachi A, Yoshinaga M, Liu J, Kanchanawong P, Tohyama K, Thumkeo D, Watanabe T, Narumiya S, Hirata T.
    • Journal Title

      PLoS ONE

      Volume: 8

    • DOI

      10.1371/journal.pone.0082590

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23229003, KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111009, KAKENHI-PROJECT-25460588, KAKENHI-PROJECT-25860188
  • [Journal Article] EphA4-dependent axon retraction and midline localization of Ephrin-B3 are disrupted in the spinal cord of mice lacking mDia1 and mDia3 in combination2013

    • Author(s)
      Yosuke Toyoda, Ryota Shinohara, Dean Thumkeo, Hiroshi Kamijo, Hiroshi Nishimaru, Hiroyuki Hioki, Takeshi Kaneko, Toshimasa Ishizaki, Tomoyuki Fnruyashiki and Shuh Narumiva
    • Journal Title

      Genes Cells.

      Volume: 18 Pages: 873-885

    • DOI

      10.1111/gtc.12081

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-13J04246, KAKENHI-PROJECT-23229003, KAKENHI-PROJECT-23500460, KAKENHI-PROJECT-24500408, KAKENHI-PROJECT-24689015, KAKENHI-PUBLICLY-25116517, KAKENHI-PUBLICLY-25116715, KAKENHI-PUBLICLY-25121714, KAKENHI-PUBLICLY-25123709, KAKENHI-PROJECT-25430109, KAKENHI-PROJECT-25860188
  • [Journal Article] A new role of multi scaffold protein Liprin- α : Liprin- α suppresses Rho-mDia mediated stress fiber formation2012

    • Author(s)
      Sakamoto S, Narumiya S, Ishizaki T
    • Journal Title

      Bioarchitecture

      Volume: 2(2) Pages: 43-49

    • DOI

      10.4161/bioa.20422

    • Data Source
      KAKENHI-PROJECT-23229003
  • [Journal Article] A role for mDia, a Rho-regulated actin nucleator, in tangential migration of interneuron precursors2012

    • Author(s)
      Shinohara R, Thumkeo D, Kamijo H, Kaneko N, Sawamoto K, Watanabe K, Takebayashi H, Kiyonari H, Ishizaki T, Furuyashiki T, Narumiya S
    • Journal Title

      Nature Neurosci

      Volume: 15(3) Pages: 373-380

    • NAID

      120003726113

    • Data Source
      KAKENHI-PROJECT-23229003
  • [Journal Article] Liprin- α controls stress fiber formation by binding to mDia and regulating its membrane localization2012

    • Author(s)
      Sakamoto S, Ishizaki T, Okawa K, Watanabe S, Arakawa T, Watanabe N, Narumiya S
    • Journal Title

      Cell Sci

      Volume: 125(1) Pages: 108-120

    • Data Source
      KAKENHI-PROJECT-23229003
  • [Journal Article] Rotational movement of the formin mDia1 along the double helical strand of an actin filament.2011

    • Author(s)
      Mizuno H, Higashida C, Yuan Y, Ishizaki T, Narumiya S, Watanabe N.
    • Journal Title

      Science. 331

      Pages: 80-83

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Journal Article] Deficiency of mDia, an actin nucleator, disrupts integrity of neuroepithelium and causes periventricular dysplasia2011

    • Author(s)
      Thumkeo D, Shinohara R, Watanabe K, Takebayashi H, Toyoda Y, Tohyama K, Ishizaki T, Furuyashiki T, Narumiya S
    • Journal Title

      PLoS One

      Volume: 6(9)

    • Data Source
      KAKENHI-PROJECT-23229003
  • [Journal Article] Impaired vascular remodeling in the yolk sac of embryos deficient in ROCK-I and ROCK-II2011

    • Author(s)
      Kamijo H, Matsumura Y, Thumkeo D, Koike S, Masu M, Shimizu Y, Ishizaki T, Narumiya S.
    • Journal Title

      Genes Cells

      Volume: 16 Pages: 1012-1021

    • DOI

      10.1111/j.1365-2443.2011.01546.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22501011, KAKENHI-PROJECT-23229003
  • [Journal Article] Fever, inflammation, pain and beyond : prostanoid receptor research during these 25 years2011

    • Author(s)
      Narumiya S, et al
    • Journal Title

      FASEB J

      Volume: 25 Pages: 813-818

    • DOI

      10.1096/fj.11-0302ufm

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23229003
  • [Journal Article] Fever, inflammation, pain and beyond : prostanoid receptor research during these 25 years.2011

    • Author(s)
      Narumiya S., et al
    • Journal Title

      FASEB J.

      Volume: 25 Pages: 813-818

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Journal Article] Rho and anillin-dependent control of mDia2localization and function in cytokinesis.2010

    • Author(s)
      Watanabe S, Okawa K, Miki T, Sakamoto S, Morinaga T, Segawa K, Arakawa T, Kinoshita M, Ishizaki T, Narumiya S.
    • Journal Title

      Mol Biol Cell. 21

      Pages: 3193-3204

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Journal Article] mDia1 targets v-Src to the cell periphery and facilitates cell transformation, tumorigenesis, and invasion.2010

    • Author(s)
      Tanji M, Ishizaki T, Ebrahimi S, Tsuboguchi Y, Sukezane T, Akagi T, Frame MC, Hashimoto N, Miyamoto S, Narumiya S.
    • Journal Title

      Mol Cell Biol. 19

      Pages: 4604-4615

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Journal Article] Rho-mDia1 pathway is required for adhesion, migration, and T-cell stimulation in dendritic cells.2010

    • Author(s)
      Tanizaki H, Egawa G, Inaba K, Honda T, Nakajima S, Moniaga CS, Otsuka A, Ishizaki T, Tomura M, Watanabe T, Miyachi Y, Narumiya S, Okada T, Kabashima K.
    • Journal Title

      Blood. 116

      Pages: 5875-5884

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Journal Article] Molecular pathway and cell state responsible for dissociation-induced apoptosis in human pluripotent stem cells.2010

    • Author(s)
      Ohgushi M, Matsumura M, Eiraku M, Murakami K, Aramaki T, Nishiyama A, Muguruma K, Nakano T, Suga H, Ueno M, Ishizaki T, Suemori H, Narumiya S, Niwa H, Sasai Y.
    • Journal Title

      Cell Stem Cell. 7

      Pages: 225-239

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Journal Article] Dual roles of PGE2-EP4 signaling in mouse experimental autoimmune encephalomyelitis.2010

    • Author(s)
      Esaki Y, Li Y, Sakata D, Yao C, Segi-Nishida E, Matsuoka T, Fukuda K, Narumiya S.
    • Journal Title

      Proc Natl Acad Sci USA. 107

      Pages: 12233-12238

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Journal Article] Prostanoids and inflammation : a new concept arising from receptor knockout mice.2009

    • Author(s)
      Narumiya S
    • Journal Title

      J Mol Med. 87

      Pages: 1015-1022

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Journal Article] Central control of fever and female body temperature by RANKL/RANK.2009

    • Author(s)
      Hanada R, Leibbrandt A, Hanada T, Kitaoka S, Furuyashiki T, Fujihara H, Trichereau J, Paolino M, Qadri F, Plehm R, Klaere S, Komnenovic V, Mimata H, Yoshimatsu H, Takahashi N, von Haeseler A, Bader M, Kilic SS, Ueta Y, Pifl C, Narumiya S,Penninger JM.
    • Journal Title

      Nature. 462

      Pages: 505-509

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Journal Article] Rho signaling, ROCK and mDial, in transformation, metastasisand invasion2009

    • Author(s)
      Narumiya, S., et.al.
    • Journal Title

      Cancer Metastasis Rev 28

      Pages: 65-76

    • Data Source
      KAKENHI-PROJECT-18002015
  • [Journal Article] mDia2 shuttles between the nucleus and the cytoplasm through the importin-α/β- and CRM1-mediated nuclear transport mechanism.2009

    • Author(s)
      Miki, T., Okawa, K., Sekimoto, T., Yoneda, Y., Watanabe, S., Ishizaki, T. & Narumiya, S.
    • Journal Title

      J. Biol. Chem. 284

      Pages: 5753-5762

    • Data Source
      KAKENHI-PROJECT-18002015
  • [Journal Article] mDia2shuttles between the nucleus and the cytoplasm through the importin-{a}/{b}- and CRM1-mediated nuclear transport mechanism.2009

    • Author(s)
      Miki T, Okawa K, Sekimoto T, Yoneda Y, Watanabe S, Ishizaki T, Narumiya S.
    • Journal Title

      J Biol Chem. 284

      Pages: 5753-5762

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Journal Article] RhoA/Rho kinase signaling in the cumulus mediates extracellular matrix assembly.2009

    • Author(s)
      Yodoi R, Tamba S, Morimoto K, Segi-Nishida E, Nishihara M, Ichikawa A, Narumiya S, Sugimoto Y.
    • Journal Title

      Endocrinology. 150

      Pages: 3345-3352

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Journal Article] Rho signaling,ROCK and mDial,in transformation, metastasis and invasion.2009

    • Author(s)
      Narumiya S., et al.
    • Journal Title

      Cancer Metastasis Rev. 28

      Pages: 87-93

    • Data Source
      KAKENHI-PROJECT-18002015
  • [Journal Article] Cdc42 and Rac family GTPases regulate mode and speed but not direction of primary fibroblast migration during platelet-derived growth factor-dependent chemotaxis.2009

    • Author(s)
      Monypenny J, Zicha D, Higashida C, Oceguera-Yanez F, Narumiya S, Watanabe N.
    • Journal Title

      Mol Cell Biol. 29

      Pages: 2730-2747

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Journal Article] Migration without a clutch.2009

    • Author(s)
      Narumiya S, et al
    • Journal Title

      Nat.Cell Biol. 11

      Pages: 1394-1396

    • Data Source
      KAKENHI-PROJECT-18002015
  • [Journal Article] Prostaglandin F(2a) receptor signaling facilitates bleomycin-induced pulmonary fibrosis independently of transforming growth factor-beta.2009

    • Author(s)
      Oga T, Matsuoka T, Yao C, Nonomura K, Kitaoka S, Sakata D, Kita Y, Tanizawa K, Taguchi Y, Chin K, Mishima M, Shimizu T, Narumiya S.
    • Journal Title

      Nat Med. 15

      Pages: 1426-1430

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Journal Article] Prostaglandin E2-EP4 signaling promotes immune inflammation through Th1 cell differentiation and Th17 cell expansion.2009

    • Author(s)
      Yao C, Sakata D, Esaki Y, Li Y, Matsuoka T, Kuroiwa K, Sugimoto Y, Narumiya S.
    • Journal Title

      Nat Med. 15

      Pages: 633-640

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Journal Article] Imatinib mesylate (STI571)-induced cell edge translocation of kinase-active and kinase-defective Abelson kinase: requirements of myristoylation and src homology 3 domain.2009

    • Author(s)
      Fujita A, Shishido T, Yuan Y, Inamoto E, Narumiya S, Watanabe N.
    • Journal Title

      Mol Pharmacol. 75

      Pages: 75-84

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Journal Article] G-actin regulates rapid induction of actin nucleation by mDia1 to restore cellular actin polymers.2008

    • Author(s)
      Higashida C, Suetsugu S, Tsuji T, Monypenny J, Narumiya S, Watanabe N.
    • Journal Title

      J Cell Sci. 121

      Pages: 3403-3412

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Journal Article] mDia2 induces the actin scaffold for the contractile ring and stabilizes its position during cytokinesis in NIH 3T3 cells.2008

    • Author(s)
      Watanabe, S., Ando, Y., Yasuda, S., Hosoya, H., Watanabe, N., Ishizaki, T., and Narumiya, S.
    • Journal Title

      Mol. Biol. Cell 19

      Pages: 2328-2338

    • Data Source
      KAKENHI-PROJECT-18002015
  • [Journal Article] The mammalian formin FHOD1 is activated through phosphorylation by ROCK and mediates thrombin-induced stress fibre formation in endothelial cells.2008

    • Author(s)
      Takeya R, Taniguchi K, Narumiya S, Sumimoto H.
    • Journal Title

      EMBO J. 27

      Pages: 618-628

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Journal Article] mDia2 induces the actin scaffold for the contractile ring and stabilizes its position during cytokinesis in NIH 3T3 cells.2008

    • Author(s)
      Watanabe S, Ando Y, Yasuda S, Hosoya H, Watanabe N, Ishizaki T, Narumiya S.
    • Journal Title

      Mol Biol Cell. 19

      Pages: 2328-2338

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Journal Article] Impaired T lymphocyte trafficking in mice deficient in an actin-nucleating protein2007

    • Author(s)
      Sakata, D., Taniguchi, H., Yasuda, S., Adachi-Morishima, A., Hamazaki, Y., Nakayama, R., Miki, T., Minato, N. and Narumiya, S.
    • Journal Title

      mDia1. J. Exp. Med. 204

      Pages: 2031-2038

    • Data Source
      KAKENHI-PROJECT-18002015
  • [Journal Article] Facilitation of Th1-mediated immune response by prostaglandin E receptor EP1.2007

    • Author(s)
      Nagamachi M, Sakata D, Kabashima K, Furuyashiki T, Murata T, Segi-Nishida E, Soontrapa K, Matsuoka T, Miyachi Y, Narumiya S.
    • Journal Title

      J Exp Med. 204

      Pages: 2865-2874

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Journal Article] Impaired T lymphocyte trafficking in mice deficient in an actin-nucleating protein, mDia1.2007

    • Author(s)
      Sakata D, Taniguchi H, Yasuda S, Adachi-Morishima A, Hamazaki Y, Nakayama R, Miki T, Minato N, Narumiya S.
    • Journal Title

      J Exp Med. 204

      Pages: 2031-2038

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Journal Article] Inactivation of Rho GTPases with Clostridium difficile Toxin B Impairs Centrosomal Activation of Aurora-A in G2/M Transition of HeLa Cells.2007

    • Author(s)
      Ando, Y., Yasuda, S., Oceguera-Yanez F. and Narumiya, S.
    • Journal Title

      Mol. Cell Biol. 18

      Pages: 3752-3763

    • Data Source
      KAKENHI-PROJECT-18002015
  • [Journal Article] Inactivation of Rho GTPases with Clostridium difficile toxin B impairs centrosomal activation of Aurora-A in G2/M transition of HeLa cells.2007

    • Author(s)
      Ando Y, Yasuda S, Oceguera-Yanez F, Narumiya S.
    • Journal Title

      Mol Biol Cell. 18

      Pages: 3752-3763

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Journal Article] Rho GTPases in animal cell mitosis.2006

    • Author(s)
      Narumiya S, Yasuda, S
    • Journal Title

      Curr.Opin.Cell Biol. 18・2

      Pages: 199-205

    • Data Source
      KAKENHI-PROJECT-13002007
  • [Journal Article] Measurement of activity of Rho GTPases during mitosis2006

    • Author(s)
      Oceguera-Yanez, F, Narumiya, S.
    • Journal Title

      Methods Enzymol. 406

      Pages: 332-345

    • Data Source
      KAKENHI-PROJECT-18002015
  • [Journal Article] Rho GTPases in animal cell mitosis.2006

    • Author(s)
      Narumiya, S., Yasuda, S.
    • Journal Title

      Curr Opin Cell Biol. 18

      Pages: 199-205

    • Data Source
      KAKENHI-PROJECT-18002015
  • [Journal Article] Rho-mDia1 Pathway Regulates Cell Polarity and Focal Adhesion Turnover in Migrating Cells Through Mobilizing APC and c-Src.2006

    • Author(s)
      Yamana, N., Arakawa, Y., Nishino, T., Kurokawa, K., Tanji, M., Monypenny, J., Ishizaki, T., Bito, H., Nozaki, K., Hashimoto, N., Matsuda, M., and Narumiya, S.
    • Journal Title

      Mol. Cell Biol. 26

      Pages: 6844-6858

    • Data Source
      KAKENHI-PROJECT-18002015
  • [Journal Article] The Rho-mDia1 pathway regulates cell polarity and focal adhesion turnover in migrating cells through mobilizing Apc and c-Src.2006

    • Author(s)
      Yamana N, Arakawa Y, Nishino T, Kurokawa K, Tanji M, Itoh RE, Monypenny J, Ishizaki T, Bito H, Nozaki K, Hashimoto N, Matsuda M, Narumiya S.
    • Journal Title

      Mol Cell Biol. 26

      Pages: 6844-6858

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Journal Article] Prostacyclin-IP signaling and prostaglandin E2-EP2/EP4 signaling both mediate joint inflammation in mouse collagen-induced arthritis.2006

    • Author(s)
      Honda T, Segi-Nishida E, Miyachi Y, Narumiya S.
    • Journal Title

      J Exp Med. 203

      Pages: 325-335

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Journal Article] Ect2 and MgcRacGAP regulate the activation and function of Cdc42 in mitosis.2005

    • Author(s)
      Oceguera-Yanez, F., Kimura, K., Yasuda, S., Higashida, C., Kitamura, T., Hiraoka, Y., Haraguchi, T., Narumiya, S.
    • Journal Title

      J. Cell Biol. 168

      Pages: 221-232

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13002007
  • [Journal Article] ROCK-I regulates closure of the eyelids and ventral body wall by inducing assembly of actomyosin bundles.2005

    • Author(s)
      Shimizu, Y., Thumkeo, D., Keel, J., Ishizaki, T., Oshima, H., Oshima, M., Noda, Y., Matsumura, F., Taketo, M.M., Narumiya, S.
    • Journal Title

      J. Cell Biol. 168

      Pages: 941-953

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13002007
  • [Journal Article] A New Look at Rho GTPases in Cell Cycle : Role in Kinetochore-Microtubule Attachment.2004

    • Author(s)
      Narumiya, S., et al.
    • Journal Title

      Cell Cycle 3

      Pages: 855-857

    • Data Source
      KAKENHI-PROJECT-13002007
  • [Journal Article] Cdc42 and mDia3 regulate microtubule attachment to kinetochores.2004

    • Author(s)
      Yasuda, S., Oceguera-Yanez, F., Kato, T., Okamoto, M., Yonemura, S., Terada, Y., Ishizaki, T., Narumiya, S.
    • Journal Title

      Nature 428

      Pages: 767-771

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13002007
  • [Journal Article] Actin polymerization-driven molecular movement of mDial in living cells.2004

    • Author(s)
      Higashida, C., Miyoshi, T., Fujita, A., Oceguera-Yanez, F., Monypenny, J., Ando, Y., Narumiya, S., Watanabe, N.
    • Journal Title

      Science 303

      Pages: 2007-2010

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13002007
  • [Journal Article] Control of axon elongation via an SDF-1a/Rho/mDia pathway in cultured cerebellar granule neurons.2003

    • Author(s)
      Arakawa, Y., Bito, H., Furuyashiki, T., Tsuji, T., Takemoto-Kimura, S., Kimura, K., Nozaki, K., Hashimoto, N., Narumiya, S.
    • Journal Title

      J. Cell Biol. 161

      Pages: 381-391

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13002007
  • [Journal Article] ROCK and mDial antagonize in Rho-dependent Rac activation in Swiss 3T3 fibroblasts.2002

    • Author(s)
      Tsuji, T., Ishizaki, T., Okamoto, M., Higashida, C., Kimura, K., Furuyashiki, T., Arakawa, Y., Birge, R.B., Nakamoto, T., Hirai, H., Narumiya, S.
    • Journal Title

      J. Cell Biol. 157

      Pages: 819-830

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13002007
  • [Presentation] 制御性T 細胞に対するプロスタグランジンE2 の作用および分子制御機構の解明2021

    • Author(s)
      松浦 竜真、Thumkeo Dean、成宮 周
    • Organizer
      第140回日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-20H00498
  • [Presentation] 免疫チェックポイント阻害剤非感受性LLC1腫瘍に対するPGE2-EP2/4阻害剤の抗腫瘍効果及び作用機序の解明2021

    • Author(s)
      村田紘規、Thumkeo Dean、成宮 周
    • Organizer
      第139回日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-20H00498
  • [Presentation] PGE2-EP2/EP4 signaling mediates immunosuppression in tumor microenvironment through the facilitation of mregDC-Treg axis2021

    • Author(s)
      Thumkeo Dean, 成宮 周
    • Organizer
      第50回日本免疫学会総会
    • Data Source
      KAKENHI-PROJECT-20H00498
  • [Presentation] Prostagalndins in tumor microenvironment as revealed by scRNAseq analysis2021

    • Author(s)
      Shuh Narumiya
    • Organizer
      14th Meeting of the Asia Pacific Federation of Pharamacologists
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H00498
  • [Presentation] New compounds for atopic dermatitis promote selective AHR-induced Filaggrin transcription in NHEK cells2020

    • Author(s)
      Makio Higuchi, Dean Thumkeo, Shuh Narumiya
    • Organizer
      第137回日本薬理学会近畿支部会
    • Data Source
      KAKENHI-PROJECT-20H00498
  • [Presentation] Identify molecular mechanism of LPA on epidermal differentiation with single cell RNA sequencing2020

    • Author(s)
      Ngo Quynh Anh 、Ratklao Siriwach、Thumkeo Dean、坂本智子、渡辺亮、成宮周
    • Organizer
      京都大学メディカルイノベーション卓越大学院プログラム・医薬系研究交流サロン
    • Data Source
      KAKENHI-PROJECT-17H01531
  • [Presentation] Single cell RNA sequencing identifies a novel LPA-induced THBS1-positive keratinocyte subpopulation that is involved in wound healing2020

    • Author(s)
      Anh Quynh Ngo, Ratklao Siriwach, Dean Thumkeo, Shuh Narumiya
    • Organizer
      第138回日本薬理学会近畿支部会
    • Data Source
      KAKENHI-PROJECT-20H00498
  • [Presentation] Prostaglandins; Inflammation and Beyond2019

    • Author(s)
      Shuh Narumiya
    • Organizer
      The 60th International Conference on thr Bioscience of Lipids
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H01531
  • [Presentation] Critical role of formin-dependent cortical F-actin remodeling in TCR signaling2019

    • Author(s)
      桂義親、Thumkeo Dean, 成宮周
    • Organizer
      第92回 日本薬理学会年会, 大阪
    • Data Source
      KAKENHI-PROJECT-17H01531
  • [Presentation] LPA induces keratinocyte differentiation and promotes skin barrier function through the LPAR1/LPRA5-RHO-ROCK-SRF axis2019

    • Author(s)
      Dean Thumkeo, Shuh Narumiya
    • Organizer
      The 60th International Conference on the Bioscience of Lipids
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H01531
  • [Presentation] mDia1/3 facilitate Lat phosphorylation by Zap70 via the spatiotemporal control of F-actin polymerization at the immune synapse.2019

    • Author(s)
      Dean Thumkeo, Yoshichika Katsura, Yukako Nishimura, Pakorn Kanchanawong, Naoki Watanabe, Matthew F. Krummel, Shuh Narumiya
    • Organizer
      ASCB EMBO 2019 Meetin
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H01531
  • [Presentation] リゾホスファチジン酸(LPA)によるヒト表皮細胞の分化誘導及び皮膚バリア機能の促進2018

    • Author(s)
      田邊滉平、Thumkeo Dean, 成宮周
    • Organizer
      第134回日本薬理学会近畿部会, 神戸
    • Data Source
      KAKENHI-PROJECT-17H01531
  • [Presentation] Indispensable role of formin-dependent cortical F-actin remodeling in TCR signaling2018

    • Author(s)
      Dean Thumkeo, Matthew Krummel, Shuh Narumiya
    • Organizer
      EMBO Workshop “Lymphocyte antigen receptor signaling”, Sienna, Italy
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H01531
  • [Presentation] Roles of prostaglandins E2-EP2 signaling in colitis-associated cancer model2018

    • Author(s)
      Dean Thumkeo, Xiaojun Ma, Jinju Lee, Shuh Narumiya
    • Organizer
      第45回内藤カンファレンス “Immunological and Molecular Bases for Cancer Immunotherapy”、北海道
    • Data Source
      KAKENHI-PROJECT-17H01531
  • [Presentation] Lysophosphatidic acid facilitates human keratinocyte differentiation through the LPAR1/LPAR5-Rho-ROCK-SRF axis and promotes skin barrier function2018

    • Author(s)
      Dean Thumkeo, Shuh Narumiya
    • Organizer
      第3回 京都皮膚基礎研究会, 京都
    • Data Source
      KAKENHI-PROJECT-17H01531
  • [Presentation] ヒト表皮細胞のバリア機能におけるリゾホスファチジン酸(LPA)の役割解明2018

    • Author(s)
      田邊滉平、Thumkeo Dean, Siriwach Ratklao, 青木淳賢、成宮周
    • Organizer
      第133回日本薬理学会近畿部会, 広島
    • Data Source
      KAKENHI-PROJECT-17H01531
  • [Presentation] アクチン制御タンパクforminのT細胞受容体シグナル伝達における機能解析2018

    • Author(s)
      桂義親、Thumkeo Dean, 成宮周
    • Organizer
      第133回日本薬理学会近畿部会, 広島
    • Data Source
      KAKENHI-PROJECT-17H01531
  • [Presentation] IL-23 generates pathogenic Th17 cells by trigerring T cell-intrinsic prostaglandin E2-EP2EP4 signaling2018

    • Author(s)
      Jinju Lee, Dean Thumkeo, Tomohiro Aoki, Chengcan Yao, Shuh Narumiya
    • Organizer
      The 18th World Congress of Basic and Clinical Pharmacology, Kyoto
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H01531
  • [Presentation] T細胞受容体シグナル伝達におけるforminの機能解析2018

    • Author(s)
      Yoshichika Katsura, Dean Thumkeo, Shuh Narumiya
    • Organizer
      第138回日本薬理学会関東部会, 東京
    • Data Source
      KAKENHI-PROJECT-17H01531
  • [Presentation] Indispensible role of formin-dependent cortical F-actin remodeling in TCR signaling2018

    • Author(s)
      Yoshichika Katsura, Dean Thumkeo, Shuh Narumiya
    • Organizer
      The 18th World Congress of Basic and Clinical Pharmacology, Kyoto
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H01531
  • [Presentation] Lysophosphatidic acid facilitates human keratinocyte differentiation through the LPAR1/LPRA5-Rho-ROCK-SRF axis and promotes skin barrier function2018

    • Author(s)
      Kohei Tanabe, Dean Thumkeo, Ratklao Siriwach, Junken Aoki, Shuh Narumiya
    • Organizer
      The 18th World Congress of Basic and Clinical Pharmacology, Kyoto
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H01531
  • [Presentation] PGE2-EP2/EP4シグナリングによるTh17細胞の増殖制御機構とその病理に対する寄与2017

    • Author(s)
      Jinju Lee, Tomohiro Aoki, Dean Thumkeo, Shuh Narumiya
    • Organizer
      第132回日本薬理学会近畿部会, 大阪
    • Data Source
      KAKENHI-PROJECT-17H01531
  • [Presentation] 目の発生におけるmDiaの機能解析2017

    • Author(s)
      タムケオ ディーン、坂本智子、符毅欣、成宮周
    • Organizer
      第90回 日本薬理学会年会
    • Place of Presentation
      長崎:長崎パブリックホール
    • Year and Date
      2017-03-17
    • Data Source
      KAKENHI-PROJECT-26221302
  • [Presentation] 免疫シナプスにおけるmDia1/3依存的なF-actinの機能解析2017

    • Author(s)
      桂善親、タムケオ ディーン、成宮周
    • Organizer
      第90回 日本薬理学会年会
    • Place of Presentation
      長崎:長崎パブリックホール
    • Year and Date
      2017-03-17
    • Data Source
      KAKENHI-PROJECT-26221302
  • [Presentation] Lysophosphatidic acid induces Filaggrin expression and promotes skin barrier function in human keratinocyte2017

    • Author(s)
      Ratklao Siriwach, Akiko Sumitomo, Kentaro Ito, Kohei Tanabe, Dean Thumkeo, Shuh Narumiya
    • Organizer
      第132回日本薬理学会近畿部会, 大阪
    • Data Source
      KAKENHI-PROJECT-17H01531
  • [Presentation] 精子形成におけるmDia1/3の機能解析2017

    • Author(s)
      符毅欣、坂本智子、タムケオ ディーン、成宮周
    • Organizer
      第90回 日本薬理学会年会
    • Place of Presentation
      長崎:長崎パブリックホール
    • Year and Date
      2017-03-17
    • Data Source
      KAKENHI-PROJECT-26221302
  • [Presentation] TCRシグナル伝達におけるformin依存的なアクチンの機能解析2017

    • Author(s)
      Yoshichika Katsura, Dean Thumkeo, Shuh Narumiya
    • Organizer
      第132回日本薬理学会近畿部会, 大阪
    • Data Source
      KAKENHI-PROJECT-17H01531
  • [Presentation] Regulation of cortical F-actin meshwork architecture in Sertoli cell by mDia1/32016

    • Author(s)
      タムケオ ディーン、坂本智子、成宮周
    • Organizer
      生体運動合同班会議
    • Place of Presentation
      京都市
    • Year and Date
      2016-01-08
    • Data Source
      KAKENHI-PROJECT-26221302
  • [Presentation] Indispensable role of mDia1/3 in sperm morphogenesis through the remodeling of Sertoli cell meshwork F-actin2016

    • Author(s)
      タムケオ ディーン、坂本智子、成宮周
    • Organizer
      第89回日本薬理学会
    • Place of Presentation
      横浜市
    • Year and Date
      2016-03-10
    • Data Source
      KAKENHI-PROJECT-26221302
  • [Presentation] Roles of mDia1/3 in neuroepithelium integrity and neuroblast migration2015

    • Author(s)
      Dean Thumkeo, Ryota Shinohara, Shuh Narumiya
    • Organizer
      The 56th Annual Meeting of the American Society for Cell Biology
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2015-12-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26221302
  • [Presentation] mDia1/3-mediated cortical F-actin assembly is required for T cell receptor signaling2015

    • Author(s)
      Dean Thumkeo, Kiyoshi Tohyama, Pakorn Kanchanawong, Shuh Narumiya
    • Organizer
      第67回日本細胞生物学会
    • Place of Presentation
      東京都
    • Year and Date
      2015-07-02
    • Data Source
      KAKENHI-PROJECT-26221302
  • [Presentation] 精子形成におけるRho標的タンパク質・フォルミンファミリーアクチン核化因子mDiaの役割解明2015

    • Author(s)
      坂本智子、タムケオ ディーン、伊川正人、藤原祥高、大田浩、渡邉定則、成宮周
    • Organizer
      第67回日本細胞生物学会
    • Place of Presentation
      東京都
    • Year and Date
      2015-07-02
    • Data Source
      KAKENHI-PROJECT-26221302
  • [Presentation] プロスタノイド受容体とRho2012

    • Author(s)
      Narumiya S
    • Organizer
      日本生理学会
    • Place of Presentation
      松本・松本文化会館(招待講演)
    • Year and Date
      2012-03-30
    • Data Source
      KAKENHI-PROJECT-23229003
  • [Presentation] プロスタノイド受容体とRho GTPasesの薬理学2012

    • Author(s)
      Narumiya S
    • Organizer
      日本薬理学会
    • Place of Presentation
      京都・国立京都国際会館(招待講演)
    • Year and Date
      2012-03-15
    • Data Source
      KAKENHI-PROJECT-23229003
  • [Presentation] Rho-mDia Pathway in the Cell, The Tissue and the Body2012

    • Author(s)
      成宮 周
    • Organizer
      Cold Spring Harbor Conferences Asia
    • Place of Presentation
      Suzhou, China
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229003
  • [Presentation] Rho-mDia Signaling: Regulation and actions in Cells and Tissue2012

    • Author(s)
      成宮 周
    • Organizer
      International Meeting of the German Society for Cell Biology on Actin Dynamics
    • Place of Presentation
      Regensburg, Germany
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229003
  • [Presentation] Rho-mDia signaling; regulation and actions in cells and tissues2012

    • Author(s)
      Narumiya, S
    • Organizer
      The 2nd Internaitonal Meeting of the German Society for Cell Biology on "Actin Dynamics"
    • Place of Presentation
      Regensburg, Germany
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229003
  • [Presentation] Rho-mDia pathway in the cell, the tissue and the body2012

    • Author(s)
      Narumiya, S
    • Organizer
      The 2012 Cold Spring Harbor Asia Conference on "Small GTPases at Different Scales : proteins, membranes, cells"
    • Place of Presentation
      Suzhou, China
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229003
  • [Presentation] Phenotype analysis of mDia-deficient mice, impaired neuroblast migration and disordered proliferation of neural stem cells2011

    • Author(s)
      Narumiya S
    • Organizer
      Gordon Research Conference on Mchanism of Cell Signaling
    • Place of Presentation
      Lowiston, USA(招待講演)
    • Data Source
      KAKENHI-PROJECT-23229003
  • [Presentation] Phenotype analysis of mDia-deficient mice; impaired neurblast migration and disordered proliferaitotn of neural stem cells2011

    • Author(s)
      Narumiya, S
    • Organizer
      Gordon Research Conference on Mechanism of Cell Signaling
    • Place of Presentation
      Maine, U.S.A.
    • Year and Date
      2011-08-01
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229003
  • [Presentation] Rhoによるアクチン骨格制御;分子の働きから生理的意義まで2011

    • Author(s)
      Narumiya S
    • Organizer
      日本生化学会大会
    • Place of Presentation
      京都・国立京都国際会館(招待講演)
    • Year and Date
      2011-09-21
    • Data Source
      KAKENHI-PROJECT-23229003
  • [Presentation] Rho-mediated regulation of actin cytoskeleton; from single molecule actions to significance in the body. Plenary Lecture2011

    • Author(s)
      Narumiya, S
    • Organizer
      The 84th Annual Meeting of the Japanese Biochemical Society
    • Place of Presentation
      Kyoto, Japan
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229003
  • [Presentation]2010

    • Author(s)
      成宮周
    • Organizer
      INSINET Symposium on Receptors, Signaling Network and Disease
    • Place of Presentation
      Madrid, Spain(招待講演)
    • Year and Date
      2010-09-24
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Presentation] Phenotype Analysis of Mice Deficient in Actin Nucleator, mDia2010

    • Author(s)
      成宮周
    • Organizer
      4^<th> Mechanobiology Wiorkshop and Biophysical Society Meeting
    • Place of Presentation
      Singapore(招待講演)
    • Year and Date
      2010-11-11
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Presentation] Physiology and Pathophysiology of Prostanoid receptors2010

    • Author(s)
      成宮周
    • Organizer
      The 14^<th> nternational Congress of Endocrinology
    • Place of Presentation
      Kyoto
    • Year and Date
      2010-03-28
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Presentation] Prostanoids and Immune Inflammation2010

    • Author(s)
      成宮周
    • Organizer
      Bioactive Lipids : Biochemistry and Diseases on Keystone Symposia
    • Place of Presentation
      Kyoto, Japan(招待講演)
    • Year and Date
      2010-06-11
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Presentation] Prostaglandins, Inflammation and respiratory diseases2010

    • Author(s)
      成宮周
    • Organizer
      Pacifichem 2010 Conference
    • Place of Presentation
      Hawaii, USA(招待講演)
    • Year and Date
      2010-12-17
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Presentation] Phenotype Analysis of Mice Deficient in Actin Nucleator, mDia2010

    • Author(s)
      Narumiya S.
    • Organizer
      4th Mechanobiology Workshop and Biophysical Society Meeting
    • Place of Presentation
      Singapore
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Presentation] Physiology, Pathophysiology of Prostanoids ; Novel roles revealed by receptor KO mouse studies2009

    • Author(s)
      成宮周
    • Organizer
      The 9^<th> Intemational Symposium on VIP, PACAP and related peptides
    • Place of Presentation
      Kagoshima, Japan
    • Year and Date
      2009-10-07
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Presentation] Functions of the Rho-mDia pathway in the body ; lessonsfrom knockout mice2009

    • Author(s)
      成宮周
    • Organizer
      The Gordon Research Conference on "Mechanisms of Cell Signaling
    • Place of Presentation
      Magdalene College, Oxoford, U.K.
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Presentation] Prostanoid Receptors : Physiology, Pathophysiology and Therapeutic Implications2009

    • Author(s)
      成宮周
    • Organizer
      Symposium on "From animal models to Clinical Application", World Health Summit
    • Place of Presentation
      Charite Berlin, Berlin, Germany
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Presentation] Rho-mDia pathway, Src and cell transformation2009

    • Author(s)
      成宮周
    • Organizer
      Special Lecture, The 24th Annual Conference of Biomedical Science
    • Place of Presentation
      Taipei, Taiwan
    • Year and Date
      2009-03-21
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Presentation] Prostaglandins, a linker between immunity and inflammation2009

    • Author(s)
      成宮周
    • Organizer
      The 39^<th> Amumal Meeting of the Japanese Immunolgy Society
    • Place of Presentation
      Osaka, Japan.
    • Year and Date
      2009-12-04
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Presentation] Prostaglandins and Inflammation ; A new concept from receptor KO mice studies.2009

    • Author(s)
      成宮周
    • Organizer
      The 43^<rd> Annual Scientific Meeting of the Australasian Society of clinical anc Experimental Pharmacologists and Toxicologists (ASCEPT).
    • Place of Presentation
      Sydney, Australia
    • Year and Date
      2009-11-30
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Presentation] Prostanoid Receptors ; Pathophysiological. roles and drug development2009

    • Author(s)
      成宮周
    • Organizer
      Special lecture, the 129th Annual Meeting of, the Pharmaceutical Society of Japan
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2009-03-27
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Presentation] Functions of the Rho-mDia pathway in the body; lessons from knockout mice2009

    • Author(s)
      Narumiya S.
    • Organizer
      The Gordon Research Conference on "Mechanisms of Cell Signaling"
    • Place of Presentation
      Magdalene College, Oxoford, U.K.
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Presentation] Prostanoid receptors in diseases and drug development2009

    • Author(s)
      成宮周
    • Organizer
      日本薬学会特別講演
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2009-03-27
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Presentation] Prostaglandins and Inflammation ; A new concept from receptor KO mice studies2009

    • Author(s)
      成宮周
    • Organizer
      Nobel Forum China
    • Place of Presentation
      Beijing, China
    • Year and Date
      2009-12-07
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Presentation] Activation of drug discovery research and industry-academia-government cooperation2009

    • Author(s)
      成宮周
    • Organizer
      第82回日本薬理学会年会
    • Place of Presentation
      Yokohama, Japan
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Presentation] Roles of Prostaglandins in diseases ; Lessons from receptor-KO mice2009

    • Author(s)
      成宮周
    • Organizer
      微小循環学会
    • Place of Presentation
      Tokyo, Japan
    • Year and Date
      2009-02-20
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Presentation] Prostanoids in inflammation ; a new concept arising from receptor-knockout mouse studies2009

    • Author(s)
      成宮周
    • Organizer
      The 9^<th> World Congress on Inflammation
    • Place of Presentation
      Tokyo
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Presentation] The Rho-mDial pathway in cell transformation and migration.2008

    • Author(s)
      成宮 周
    • Organizer
      An AACR special Conference in Cancer Research "Cytoskeleton Signaling in Cancer
    • Place of Presentation
      San Diego, U.S.A.
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Presentation] Physiology and Clinical Application of the Prostanoid Receptor2008

    • Author(s)
      成宮周
    • Organizer
      京都大学国際シンポジウム
    • Place of Presentation
      副旦大学, Shanhai, China
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Presentation] Rho-mDia pathway, Src and cell transformation2008

    • Author(s)
      Narumiya S.
    • Organizer
      Gordon Conference on Phosphorylation and G-protein mediated Signaling Networks
    • Place of Presentation
      University of New England, Maine, U.S.A.
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Presentation] The Rho-mDia Pathway in Cell Transformaiton and Migration2008

    • Author(s)
      Narumiya S.
    • Organizer
      The AACR Special Conference in Cancer Researh on Cytoskeleotn Signaling in Cancer
    • Place of Presentation
      San Diego, U.S.A.
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Presentation] Prostanoid receptors in signaling network of chronic inflammation", The Keystone Symposium on Eicosanoids and Other Lipid Mediators of Chronic Inflammation2008

    • Author(s)
      成宮 周
    • Organizer
      The Keystone Symposium on Eicosanoids and Other Lipid Mediators of Chronic Inflammation
    • Place of Presentation
      Big Sky Resort, Montana, U.S.A.
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Presentation] Prostanoid receptors: From physiology, Molecular Biology to Translational Research2008

    • Author(s)
      成宮 周
    • Organizer
      The Lecture at the 12oth Aniversary of Siriraj Hospital
    • Place of Presentation
      Bangkok, Thailand
    • Year and Date
      2008-03-21
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Presentation] Rho -mDia pathway, Src and cell transformation2008

    • Author(s)
      成宮周
    • Organizer
      Gordon Conference on Phosphorylation and G-protein mediated Signaling Networks
    • Place of Presentation
      University of New England,, Maine,. U.S.A
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Presentation] Physiology and Clinical Application of the Prostanoid Receptors2008

    • Author(s)
      成宮周
    • Organizer
      The Keystone Symposium on G protein-coupled Receptors : New Insights in Functional Regulation and Clinical Application
    • Place of Presentation
      The Keystone Symposium on G protein-coupled Receptors : New Insights in Functional Regulation and Clinical Application
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Presentation] Rho-mDia pathway, Src and cell transformation2008

    • Author(s)
      成宮周
    • Organizer
      臨床分子医学会
    • Place of Presentation
      Kobe, Japan
    • Year and Date
      2008-07-25
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Presentation] プロスタノイド受容体:cDNAクローニングから探索臨床まで2007

    • Author(s)
      成宮 周
    • Organizer
      第48回日本脈管学会総会教育講演
    • Place of Presentation
      松本
    • Year and Date
      2007-10-25
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Presentation] mDia Isoforms Mediate Delivery of c-Src and Spindle Orientation through Actin Cytoskeleton; A Conserved Mechanism from Yeast to Mammals2007

    • Author(s)
      Narumiya S.
    • Organizer
      ASCB-ECF Summer Meeting Dynamic Interplay Between Cytoskeletal and Membrane Systems, Dijon Congrexpo
    • Place of Presentation
      Dijon, France.
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Presentation] Rho GTPases in Cell Division; From G2/M Transiiton to Cytokinesis.2007

    • Author(s)
      成宮 周
    • Organizer
      The Gordon Research Conference on Mchanism of Cell Signaling
    • Place of Presentation
      Magdalen Collese, Oxford, U.K.
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Presentation] 「毒素と化合物;機能解析ツールとしての有用性と薬物開発へのポテンシャル」2007

    • Author(s)
      成宮 周
    • Organizer
      日本ケミカルバイオロジー研究会 特別講演
    • Place of Presentation
      京都大学
    • Year and Date
      2007-05-09
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Presentation] プロスタグランジン:シグナル伝達と位置づけ2007

    • Author(s)
      成宮 周
    • Organizer
      第80回日本生化学会大会・第30回日本分子生物学会年会合同大会シンポジウム
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Presentation] mDia Isoforms Mediate Delivery of c-Src and Spindle Orientation through Actin Cytoskeleton; A Conserved Mechanism from Yeast to Mammals?2007

    • Author(s)
      成宮 周
    • Organizer
      2007 ASCB-ECF Summer Meeting Dynamic Interplay Between Cytoskeletal and Membrane Systems, Di jon Congrexpo
    • Place of Presentation
      Di jon, France
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Presentation] 炎症・アレルギー・免疫・プロスタノイド2007

    • Author(s)
      成宮 周
    • Organizer
      第28回日本炎症・再生医学会 特別講演
    • Place of Presentation
      東京京王プラザホテル
    • Year and Date
      2007-08-02
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Presentation] Rho signaling : Roles and Mechanism in Cell Morphogenesis and Movement2007

    • Author(s)
      Narumiya S.
    • Organizer
      Dana-Farber Cancer Institute Seminars in Oncology
    • Place of Presentation
      Dana-Farber Cancer Institute, Harvard Medical School, Boston, U.S.A.
    • Year and Date
      2007-04-03
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Presentation] Cytoskeleton Remodeling by Rho GTPases and Effectors in cell morphogenesis, migration and mitosis.The Symposium on Cytoskeleon: dynamics and structural basis of cytoskeleton assembly2006

    • Author(s)
      Narumiya S.
    • Organizer
      The 20th IUBMB International Congress of Biochemistry and Molecular Biology and the 11th FAOBMB Congress
    • Place of Presentation
      Kyoto, Japan.
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Presentation] Rho GTPases in animal cell mitosis2006

    • Author(s)
      Narumiya S.
    • Organizer
      FASEB Summer Research Conference on Regulation & Function of Small GTPases
    • Place of Presentation
      Vermont Academy, Vermont, U.S.A.
    • Data Source
      KAKENHI-PROJECT-18002015
  • [Presentation] アクチン重合分子mDia2によるマウス発生期の赤芽球細胞質分裂の調節

    • Author(s)
      渡邉定則、デザンティハナ、五島剛太、成宮周
    • Organizer
      第65回 日本細胞生物学会大会
    • Place of Presentation
      名古屋
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229003
  • [Presentation] A role for mDia, a Rho-regulated actin nucleator, in emotional changes induced by social isolation stress

    • Author(s)
      出口 雄一,篠原 亮太 , Michael Lazarus , Yoan Cherasse, 裏出 良博 ,古屋敷 智之、成宮 周
    • Organizer
      日本神経科学会Neuro2013
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23229003
  • [Presentation] mDia1 and mDia3, formin family actin nucleators and Rho effectors, mediate TCR microcluster dynamics and signaling and are critical for positive selection of thymocytes.

    • Author(s)
      Narumiya, S., Thumkeo, D., Beemiller, O. and Krummel, M.F.
    • Organizer
      The 2014 Cold Spring Harbor Asia Conference on “GTPases: Mechanisms, interactions and applications”
    • Place of Presentation
      Suzhou, China
    • Year and Date
      2014-09-22 – 2014-09-26
    • Invited
    • Data Source
      KAKENHI-PROJECT-26221302
  • [Presentation] Roles of mDia in TCR signaling and its potential as a novel target for immunoregualtion drugs.

    • Author(s)
      Dean Thumkeo and Shuh Narumiya
    • Organizer
      The 2nd International Conference in Medicine and Public Health
    • Place of Presentation
      Bangkok, Thailand
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229003
  • [Presentation] Physiological roles of mDia, a Rho effector and actin nucleator, in mammals.

    • Author(s)
      Dean Thumkeo, Sadanori Watanabe and Shuh Narumiya
    • Organizer
      日本生化学会第86回大会シンポジウム
    • Place of Presentation
      横浜
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229003
  • [Presentation] A role for mDia, a Rho-regulated actin nucleator, in regulating morphology of presynaptic terminals and increased anxiety-like behavior induced by social isolation stress in mice.

    • Author(s)
      Deguchi, Y., Harada, M., Shinohara, R., Lazarus, M., Cherasse, Y., Urade, Y., Watanabe, D., Furuyashiki T., and Narumiya, S.
    • Organizer
      The 88th Annual Meeting of the Japanese Pharmacological Society
    • Place of Presentation
      Nagoya, Japan
    • Year and Date
      2014-09-11 – 2014-09-13
    • Data Source
      KAKENHI-PROJECT-26221302
  • [Presentation] Roles of mDia in TCR signaling and its potential as a novel target for immunoregualtion drugs

    • Author(s)
      Dean, T, Watanabe, S., and Narumiya, S
    • Organizer
      The 2nd International Conference in Medicine and Public Health
    • Place of Presentation
      Bangkok, Thailand
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229003
  • [Presentation] Formin family actin nucleators, mDia1 and mDia3, mediate TCR microcluster dynamics and signaling critical for positive selection of thymocytes.

    • Author(s)
      Thumkeo, D., Nomachi, A., Tohyama, K., and Narumiya, S.
    • Organizer
      The 88th Annual Meeting of the Japanese Pharmacological Society.
    • Place of Presentation
      Nagoya, Japan
    • Year and Date
      2015-03-18 – 2015-03-20
    • Data Source
      KAKENHI-PROJECT-26221302
  • [Presentation] mDia, an actin nucleator of formin family, functions in T cell activation.

    • Author(s)
      Kiyoshi Tohyama, Dean Thumkeo and Shuh Narumiya
    • Organizer
      日本薬理学会第87回年会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-23229003
  • [Presentation] The formin protein mDia is indispensible for TCR signaling dependent T cell development through actin nucleation activity.

    • Author(s)
      Thumkeo, D., Beemiller, P., Nomachi, A., Krummel, M.F. and Narumiya, S.
    • Organizer
      The 66th Annual Meeting of the Japanese Society for Cell Biology
    • Place of Presentation
      Nara, Japan
    • Year and Date
      2014-06-11 – 2014-06-13
    • Data Source
      KAKENHI-PROJECT-26221302
  • [Presentation] Rho-mDia signaling in developing nervous system

    • Author(s)
      Dean, T, Shinohara, R. and Narumiya, S
    • Organizer
      The 84th Annual Meeting of the Japanese Pharmacological Society
    • Place of Presentation
      Yokohama, Japan
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229003
  • [Presentation] My Adventures in Medical Research; Prostanoid Receptors and Rho GTPase

    • Author(s)
      Narumiya, S
    • Organizer
      The 89th Annual Meeting of the Physiological Society of Japan
    • Place of Presentation
      Matsumoto, Japan
    • Invited
    • Data Source
      KAKENHI-PROJECT-23229003
  • [Presentation] Role of mDia in Spermatogenesis.

    • Author(s)
      Sakamoto, S., Thumkeo, D., and Narumiya, S.
    • Organizer
      he 66th Annual Meeting of the Japanese Society for Cell Biology.
    • Place of Presentation
      Nara, Japan
    • Year and Date
      2014-06-11 – 2014-06-13
    • Data Source
      KAKENHI-PROJECT-26221302
  • [Presentation] A role for mDia, a Rho-regulated actin nucleator, in elevated anxiety induced by social isolation stress in mice

    • Author(s)
      出口雄一、原田征弥、篠原亮太,」MichaelLazarus, Yoan Cherasse, 裏出良博、古屋敷智之、成宮周
    • Organizer
      日本薬理学会第87回年会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-23229003
  • [Presentation] Actin nucleator mDia1 and mDia3, cooperatively function in T cell receptor signaling-dependent T cell development in thymus.

    • Author(s)
      Dean Thumkeo, Akira Nomachi, Kiyoshi Tohyama, Takako Hirata, Toshimasa Ishizaki and Shuh Narumiya
    • Organizer
      日本薬理学会第87回年会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-23229003
  • [Presentation] Indispensable role of formin family actin nucleator, mDia1 and mDia3, in TCR microcluster dynamics and signaling critical for positive selection of thymocytes.

    • Author(s)
      Thumkeo, D., Beemiller, P., Nomachi, A., Krummel, M.F. and Narumiya, S.
    • Organizer
      The 37th Naito Conference “Bioimaging-a paradigm shift for the life science”.
    • Place of Presentation
      Niseko, Hokkaido, Japan
    • Year and Date
      2014-07-15 – 2014-07-18
    • Data Source
      KAKENHI-PROJECT-26221302
  • [Presentation] T cell cortical F-actin is mediated by mDia and critical for TCR signaling.

    • Author(s)
      Tohyama, K., Thumkeo, D., and Narumiya, S.
    • Organizer
      The 88th Annual Meeting of the Japanese Pharmacological Society.
    • Place of Presentation
      Nagoya, Japan
    • Year and Date
      2015-03-18 – 2015-03-20
    • Data Source
      KAKENHI-PROJECT-26221302
  • [Presentation] Loss of a Rho-regulated actin nucleator, mDia2, impairs cytokinesis during fetal erythropoiesis.

    • Author(s)
      Watanabe S, De Zan T, Goshima G, and Narumiya S.
    • Organizer
      The 61th NIBB Conference
    • Place of Presentation
      岡崎
    • Data Source
      KAKENHI-PROJECT-23229003
  • [Presentation] A role for mDia, a Rho-regulated actin nucleator, in chronic stress-induced behavioral changes and synaptic plasticity.

    • Author(s)
      Deguchi, Y., Harada, M., Shinohara, R., Watanave, D., Furuyashiki, T., and Narumiya, S.
    • Organizer
      The 2014 Cold Spring Harbor Asia Conference on “GTPases: Mechanisms, interactions and applications”
    • Place of Presentation
      Suzhou, China
    • Year and Date
      2014-09-22 – 2014-09-26
    • Data Source
      KAKENHI-PROJECT-26221302
  • [Presentation] A role for mDia, a Rho-regulated actin nucleator, in chronic stress-induced behavioral changes and synaptic plasticity.

    • Author(s)
      Deguchi, Y., Harada, M., Shinohara, R., Lazarus, M., Cherasse, Y., Urade, Y., Watanabe, D., Furuyashiki, T., and Narumiya, S.
    • Organizer
      第37回日本神経科学大会
    • Place of Presentation
      Yokohama, Japan
    • Year and Date
      2014-09-11 – 2014-09-13
    • Data Source
      KAKENHI-PROJECT-26221302
  • [Presentation] 毒素研究から細胞生物学へ : Rho 研究の冒険

    • Author(s)
      成宮周
    • Organizer
      第152回日本獣医学会学術集会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-23229003
  • 1.  FUJIWARA Motohatsu (90025536)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 2.  MORII Narito (80220036)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 3.  MIWA Soichi (40157706)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 4.  斉藤 雄二 (40263090)
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  • 6.  KAKIZUKA Akira (80204329)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 1 results
  • 7.  USHIKUBI Fumitaka (50243035)
    # of Collaborated Projects: 3 results
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  • 8.  TANIGUCHI Takashi (10111957)
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    # of Collaborated Products: 6 results
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  • 13.  NOZAWA Yoshinori (10021362)
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  • 14.  MOMIYAMA Toshihiko (20230055)
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    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
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    # of Collaborated Projects: 1 results
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  • 188.  日置 寛之
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