Suzuki Masaaki 鈴木正昭

… Alternative Names

Researcher Number	90093046
External Links
Affiliation (Current)	2019: 国立研究開発法人国立長寿医療研究センター, 認知症先進医療開発センター, 研究員
Affiliation (based on the past Project Information) *help	2019: 国立研究開発法人国立長寿医療研究センター, 認知症先進医療開発センター, 研究員 2018: 国立研究開発法人国立長寿医療研究センター, その他部局等, 研究員 2017: 国立研究開発法人国立長寿医療研究センター, 脳機能画像診断開発部, 研究員 2015: 国立研究開発法人国立長寿医療研究センター, 能機能画像診断開発部, 特任研究員 2015: 国立研究開発法人国立長寿医療研究センター, 脳機能画像診断開発部, 研究員 … More
Review Section/Research Field	Principal Investigator Bioorganic chemistry / 天然物有機化学 / Biomolecular chemistry Except Principal Investigator Cerebral neurosurgery / Pathological medical chemistry / General pharmacology / Living organism molecular science / Radiation science / Basic Section 52040:Radiological sciences-related / Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
Keywords	Principal Investigator 15R-TIC / PET / プロスタサイクリン / IP_2 / APNIC / イソカルバサイクリン / 受容体 / 光親和性標識 / プロスタグランジン / 15-deoxy-TIC … More Except Principal Investigator プロスタグランジン / 脳腫瘍 / 15R-TIC / BINAP / PET / アルツハイマー病 / 制がん性PG / △^7ーPGA_1 / 交叉ジエノン構造 / プロスタイクリン / 受容体タンパク質 / 光親知性標識法 / 抗腫瘍性プロスタグランジン / グルタチオン抱合体 / GS-Xポンプ / シスプラチン耐性HL-60 / 光親和性標識プローブ / 耐性克服 / 薬剤耐性 / グルタチオン / シスプラチン耐性HL-60細胞 / 分子プローブ / 光親和性標識 / 抗腫瘍性 / シスプラチン耐性細胞 / HL60 / c-myc遺伝子 / 分子設計 / 機能探索分子 / プロテインキナーゼ / G蛋白質共役受容体 / Ca^<2+>イメージング / カルシウムシグナリング / ケミカルバイオロジー / ケミカルジェネティクス / 疾患ケミカルバイオロジー / リン酸化酵素阻害剤 / バイオイメージングプローブ / PETプローブ / アフィニティ磁性ナノビーズ / 創薬 / エピジェネティクス / 癌幹細胞 / エピジェネテュクス / ヒストン / メチル化 / 治療 / 分子イメージング / 分子イメーグング / MGMT / PETトレーサー / 分子 / イメージング / 有機合成 / 臨床応用 / プロスタグランジンE_2 / プロスタグランジンF_<2α> / プロスタグランジンI_2 / 受容体 / クローニング / G蛋白 / プロスタグランジンF_<2alpha> / 牛副腎髄質 / PCR / 牛卵巣黄体 / Prostaglandin E_2 / Prostaglandin F_<2alpha> / Prostaglandin I_2 / Receptor / Cloning / プロスタサイクリン / アポトーシス / 神経細胞死 / 海馬 / 中隔 / Prostacyclin / Prostaglandin / Apoptosis / Neuronal death / Hippocampus / Septum / 新有機化学反応 / 有機,鉛化合物 / 高選択的1,4ー付加反応 / パラジウム(0)錯体触媒 / 新脱保護法 / 不斉水素化 / DAIB / 有機亜鉛 / アルキル化 / 不斉クライゼン転位 / アリル系保護基 / 超純度DNA合成 / 超原子価スズ化合物 / 分子内エン反応 / アミノアルコール / 有機亜鉛化合物 / アシロキシボラン / 不斉DielsーAlder反応 / BINAP錯体 / プロスタグランジン合成 / DNA固相合成 / 不斉アルキル化 / 有機アルミニウム / 不斉増幅 / 不斉触媒 / O価バラジウム / 2-5A / アントラサイクリン / アリルオキシカルボニル / パラジウム / イソカルバサイクリン / ルテニウム錯体 / 1-βメチルチエナマイシン / ナブロキャン / シトロネロール / ビタミン / BINAL-H / TMSOTf / BINAP-Rh / BINAP-Ru / MAD / CAB / Pd(0)Catalyzed deprotection / マイクロドーズ試験 / アルツハイマー / タウ蛋白 / イソプロテレノール / 陽電子断層撮像法 / 被曝線量 / MIRD法 / マイクログリア / 神経炎症 / CSF1R / 非環式レチノイド / 11C標識分子プローブ / プロドラッグ / 脳内移行性 Less

PET imaging of microglia, a novel drug target for neurodegenerative diseasesOngoing
- Principal Investigator
  
  木村泰之
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  National Center for Geriatrics and Gerontology
Synthesis of 11C-labeled acyclic retinoids with high brain permeabilityOngoing
- Principal Investigator
  
  古山浩子
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  Gifu University
PET microdose study for finding appropriate dose of isoproterenol as a disease modifying treatment of dementiaOngoing
- Principal Investigator
  
  伊藤健吾
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  National Center for Geriatrics and Gerontology
Development of PET probes of neuroprotective molecular components in oriental medicinesPrincipal Investigator
- Principal Investigator
  
  SUZUKI Masaaki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biomolecular chemistry
- Research Institution
  National Center for Geriatrics and Gerontology
Chemical biology reprogramming epigenetic aberration in malignant brain tumors
- Principal Investigator
  
  NATSUME Atsushi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Nagoya University
Development of molecular imaging tracers for anticancer drug resistant proteins
- Principal Investigator
  
  WAKABAYASHI Toshihiko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Nagoya University
ケミカルジェネティクスによる生体機能の解明
- Principal Investigator
  
  萩原正敏
- Project Period (FY)
  2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Living organism molecular science
- Research Institution
  Tokyo Medical and Dental University
生物新機能と創薬をめざす生体内分子科学Principal Investigator
- Principal Investigator
  
  鈴木正昭
- Project Period (FY)
  2001 – 2005
- Research Category
  
  Grant-in-Aid for Creative Scientific Research
- Research Institution
  Gifu University
生体内分子科学Principal Investigator
- Principal Investigator
  
  鈴木正昭
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Creative Basic Research
- Research Institution
  Gifu University
Biological Functions and Designed Probe CompoundsPrincipal Investigator
- Principal Investigator
  
  SUZUKI Masaaki, 日高弘義
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Gifu University
  Nagoya University
Development of Anti-apoptoic Drugs for Neuronal Cells and Distribution Analysis in BrainPrincipal Investigator
- Principal Investigator
  
  SUZUKI Masaaki
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Gifu University
Neuroprotctive effects of CNS-specific prostacyclin receptro ligands
- Principal Investigator
  
  SATOH Takumi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Osaka Bioscience Institute
Novel PET Tracers for Prostaglandin ReceptorsPrincipal Investigator
- Principal Investigator
  
  SUZUKI Masaaki
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Gifu University
標的分子の構造情報に基づく分子設計及び有機合成Principal Investigator
- Principal Investigator
  
  鈴木正昭
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Gifu University
超高感度プロスタグランジン受容体プローブの設計と活用Principal Investigator
- Principal Investigator
  
  鈴木正昭
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Gifu University
機能探索設計分子の開発とその評価
- Principal Investigator
  
  日高弘義
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Nagoya University
プロスタグランジン:生物活性分子機構Principal Investigator
- Principal Investigator
  
  鈴木正昭
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Gifu University
超高感度プロスタグランジン受容体プローブの設計と活用Principal Investigator
- Principal Investigator
  
  鈴木正昭
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Gifu University
制がん性プロスタグランジンの科学的および生物学的研究
- Principal Investigator
  
  野依良治
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Nagoya University
超高感度プロスタグランジン受容体プローブの設計と活用Principal Investigator
- Principal Investigator
  
  鈴木正昭
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Gifu University
プロスタグランジン受容体に関する有機化学的研究Principal Investigator
- Principal Investigator
  
  鈴木正昭
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Gifu University
Design of specific Molecular Probes for a Prostacyclin ReceptorPrincipal Investigator
- Principal Investigator
  
  SUZUKI Masaaki
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Gifu University
光親和性プロスタサイクリン受容体探索子の設計および活用に基づく受容体の同定Principal Investigator
- Principal Investigator
  
  鈴木正昭
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  天然物有機化学
- Research Institution
  Nagoya University
Cloning of prostaglandin E receptor cDNAs and molecular mechanisms of activation
- Principal Investigator
  
  ITO Seiji
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Osaka Bioscience Institute
制がん性プロスタグランジン類の設計と合成
- Principal Investigator
  
  NOYORI Ryoji
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Nagoya University
Development of New Organic Reactions and Synthesis of Physiologically Active Substance
- Principal Investigator
  
  NOYORI Ryoji
- Project Period (FY)
  1987 – 1990
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Research Institution
  Nagoya University
プロスタグランジン類の短段階一般合成法Principal Investigator
- Principal Investigator
  
  鈴木正昭
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  天然物有機化学
- Research Institution
  Nagoya University

All 2017 2016 2015 2014 2013 2005 2004

All Journal Article Presentation

[Journal Article] Detection of cyclooxygenase-1 in activated microglia during amyloid plaque progression: PET studies in Alzheimer’s disease model mice2016
- Author(s)
  Miho Shukuri, Aya Mawatari, Masahiro Ohno, Masaaki Suzuki, Hisashi Doi, Yasuyoshi Watanabe, Hirotaka Onoe
- Journal Title
  
  J. Nucl. Med.
  
  Volume: 57 Pages: 291-296
- DOI
  10.2967/jnumed.115.166116
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09904, KAKENHI-PROJECT-25242070
[Journal Article] Synthesis of a Vpr-binding derivative for use as a novel HIV-1 inhibitor2015
- Author(s)
  Kyoji Hagiwara, Hideki Ishii, Tomoyuki Murakami, Shin-nosuke Takashima, Nopporn Chutiwitoonchai, Eiichi N Kadama, Kumi Kawai, Yasumitsu Kondoh, Kaori Honda, Hiroyuki Osada, Yasuo Tsunetsugu-Yokota, Masaaki Suzuki, Yoko Aida
- Journal Title
  
  PLoS One
  
  Volume: 12
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25242070
[Journal Article] 11C-labeled capsaicin and its in vivo molecular imaging in rats by positron emission tomography.2015
- Author(s)
  Goto Miki, Mizuma Hiroshi, Wada Yasuhiro, Suzuki Masaaki, Watanabe Yasuhiro, Onoe Hirotaka, Doi Hisashi
- Journal Title
  
  Food Nutrit.Sci.
  
  Volume: 6 Pages: 216-220
- DOI
  10.4236/fns.2015.62022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25242070
[Journal Article] Toxic tau oligomer formation blocked by capping of cysteine residue with 1,2-dihydroxybenzene groups2015
- Author(s)
  Soeda Y, Yoshikawa M, Almeida OF, Sumioka A, Maeda S, Osada H, Kondoh Y, Saito A, Miyasaka T, Kimura T, Suzuki M, Koyama H, Yoshiike Y, Sugimoto H, Ihara Y, Takashima A
- Journal Title
  
  Nature Commun.
  
  Volume: 6 Pages: 10216-10216
- DOI
  10.1038/ncomms10216
- Peer Reviewed / Open Access / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26350976, KAKENHI-PLANNED-26117004, KAKENHI-PROJECT-25242070, KAKENHI-PROJECT-25460147
[Journal Article] A novel [11C]-labeled thymidine analog, [11C]AZT, for tumor imaging by positron emission tomography2015
- Author(s)
  Tsuyoshi Tahara, Zhouen Zhang, Masahiro Ohno, Yukako Hirano, Nami Hasaka, Hisashi Doi, Masaaki Suzuki, and Hirotaka onoe
- Journal Title
  
  EJNMMI Res.
  
  Volume: 5 Pages: 45-45
- DOI
  10.1186/s13550-015-0124-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25242070
[Journal Article] Synthesis of 11C-labeled thiamine and fursulthiamine for in vivo molecular imaging of vitamin B1 and its prodrug using positron emission tomography2015
- Author(s)
  Hisashi Doi, Aya Mawatari, Masakatsu Kanazawa, Satoshi Nozaki, Yukihiro Nomura, Takahito Kitayoshi, Kouji Akimoto, Masaaki Suzuki, Shinji Ninomiya, Yasuyoshi Watanabe
- Journal Title
  
  J. Org. Chem.
  
  Volume: 80 Pages: 6250-6258
- DOI
  10.1021/acs.joc.5b00685
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25242070
[Journal Article] Quantitative evaluation of the improvement in the pharmacokinetics of a nucleic acid drug delivery system by dynamic PET imaging with 18F-incorporated oligodeoxynucleotides.2014
- Author(s)
  H. Mukai, D. Ozaki, Y. Cui, T. Kuboyama, H. Yamato-Nagata, K. Onoe, M. Takahashi, Y. Wada, T. Imanishi, T. Kodama, S. Obika,* M Suzuki, H. Doi, Y. Watanabe
- Journal Title
  
  J. Controlle Release
  
  Volume: 180 Pages: 92-99
- DOI
  10.1016/j.jconrel.2014.02.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249007, KAKENHI-PROJECT-25242070
[Journal Article] 11C-Cetrozole: An improved C-11C-methylated PET probe for aromatase imaging in the brain.2014
- Author(s)
  Kayo Takahashi, Takamitsu Hosoya, Kayo Onoe, Hisashi, Doi, Hiroko Nagata, Toshiyuki Hiramatsu, Xiao-Le Li, Yumiko Watanabe, Yasuhiro Wada, Tadayuki Takashima, Masaaki Suzuki, Hirotaka Onoe, Yasuyoshi, Watanabe
- Journal Title
  
  Journal of Nuclear Medicine
  
  Volume: 55 Pages: 852-857
- DOI
  10.2967/jnumed.113.131474
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25242070, KAKENHI-PROJECT-25830024
[Journal Article] Efficient syntheses of [11C]zidovudine and its analogs by convenient one-pot palladium(0)-copper(I) co-mediated rapid C-[11C]methylation2014
- Author(s)
  Zhouen Zhang, Hisashi Doi, Hiroko Koyama, Yasuyoshi Watanabe, Masaaki Suzuki
- Journal Title
  
  J. Labelled Compd. Radiopharm.
  
  Volume: 57 Pages: 540-549
- DOI
  10.1002/jlcr.3213
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25242070, KAKENHI-PROJECT-25460147
[Journal Article] IOP lowering effect of isoquinoline-5-sulfonamide compounds on ocular normotensive monkey.2014
- Author(s)
  Kengo Sumi, Yoshihiro Inoue, Masahiro Nishio, Yasuhito Naito, Takamitu Hosoya, Masaaki Suzuki, Hiroyoshi Hidaka
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 24 Pages: 831-834
- DOI
  10.1016/j.bmcl.2013.12.085
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25242070
[Journal Article] Pd0-mediated rapid cross-coupling reactions, the rapid C-[11C]methylations, revolutionarily advancing the syntheses of short-lived PET molecular probes2014
- Author(s)
  Masaaki Suzuki, Hisashi Doi, Hiroko Koyama, Zhang Zhouen, Takamitsu Hosoya, Hirotaka Onoe, Yasuyoshi Watanabe
- Journal Title
  
  Chem. Rec.
  
  Volume: 14 Pages: 516-541
- DOI
  10.1002/tcr.201400002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25242070, KAKENHI-PROJECT-25460147
[Journal Article] 11C-labeling of the C(1)-C(10) dihydroxy acid moiety for the study on the synthesis of kulokekahilide-2 PET tracer.2014
- Author(s)
  Chunguang Han, Hisashi Doi, Junji Kimura, Yoichi Nakao, and Masaaki Suzuki
- Journal Title
  
  Int. J. Org. Chem.
  
  Volume: 4 Pages: 269-277
- DOI
  10.4236/ijoc.2014.44029
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25242070
[Journal Article] Synthesis of 11C-labeled retinoic acid, [11C]ATRA, via an alkenylboron precursor by Pd(0)-mediated rapid C-[11C]methylation.2014
- Author(s)
  Masaaki Suzuki, Misato Takashima-Hirano, Hideki Ishii, Chika Watanabe, Kengo Sumi, Hiroko Koyama, Hisashi Doi,
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 24 Pages: 3622-3625
- DOI
  10.1016/j.bmcl.2014.05.041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590156, KAKENHI-PROJECT-25242070, KAKENHI-PROJECT-25460147
[Journal Article] Evaluation of Bcrp Function in Hepatobiliary and Renal Excretion using PET with [11C]SC-628072013
- Author(s)
  Takashima T, Wu C, Takashima-Hirano M, Katayama Y, Wada Y, Suzuki M, Kusuhara H, Sugiyama Y and Watanabe Y.
- Journal Title
  
  J Nucl Med.
  
  Volume: 54 Pages: 267-276
- DOI
  10.2967/jnumed.112.110254
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24229002, KAKENHI-PROJECT-25242070, KAKENHI-PLANNED-23136101
[Journal Article] Evaluation of TlOH effect for Pd0-mediated cross-coupling of methyl iodide and excess boronic acid ester toward fabrication of [11C]CH3-incorporated PET tracer2013
- Author(s)
  Hiroko Koyama, Hisashi Doi, Masaaki Suzuki
- Journal Title
  
  Int. J. Org. Chem.
  
  Volume: 3 Pages: 220-223
- DOI
  10.4236/ijoc.2013.33030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25242070, KAKENHI-PROJECT-25460147
[Journal Article] Pd0-mediated rapid coupling of methyl iodide with excess amounts of pinacol benzyl- and cinnamylboronic acid estsers: efficient method for incorporation of positron-emitting 11C radionuclide into organic frameworks by coupling between two sp3-hybridized carbons2013
- Author(s)
  Hiroko Koyama, Zhouen Zhang, Ryosuke Ijuin, Siqin, Jeongwan Son, Yuma Hatta, Masashi Ohta, Masahiro Wakao, Takamitsu Hosoya, Hisashi Doi, Masaaki Suzuki
- Journal Title
  
  RSC Advances
  
  Volume: 3 Pages: 9391-9401
- DOI
  10.1039/c3ra40815a
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25242070, KAKENHI-PROJECT-25460147
[Journal Article] Dynamic Analysis of Fluid Distribution in the Gastrointestinal Tract in Rats: PET Imaging after Oral Administration of Non-absorbable Marker, [18F]Deoxyfluoropoly(ethylene glycol)2013
- Author(s)
  Takashima T, Shingaki T, Katayama Y, Hayashinaka E, Wada Y, Kataoka M, Ozaki D, Doi H, Suzuki M, Ishida S, Hatanaka K, Sugiyama Y, Akai S, Oku N, Yamashita S, Watanabe Y
- Journal Title
  
  Mol. Pharmacol.
  
  Volume: 10 Pages: 2261-2269
- DOI
  10.1021/mp300469m
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659049, KAKENHI-PROJECT-25242070
[Journal Article] Synthesis of an 11C-labeled antiprion GN8 derivative and evaluation of its brain uptake by positron emission tomography.2013
- Author(s)
  Tsutomu Kimura, Takeo Sako, Siqin, Junji Hosokawa-Muto, Yi Long Cui, Yasuhiro Wada, Yosky Kataoka, Hisashi Doi, Suehiro Sakaguchi, Masaaki Suzuki, Yasuyoshi Watanabe, Kazuo Kuwata
- Journal Title
  
  ChemMedChem
  
  Volume: 8(7) Pages: 1035-1039
- DOI
  10.1002/cmdc.201300167
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23370068, KAKENHI-PROJECT-24570180, KAKENHI-PROJECT-24659574, KAKENHI-PROJECT-25242070, KAKENHI-PROJECT-25460399
[Journal Article] Evaluation of Oatp and Mrp2 activities in hepatobiliary excretion using newly developed positron emission tomography (PET) tracer, [11C]dehydropravastatin, in rats2013
- Author(s)
  Shingaki T, Takashima T, Ijuin R, Zhang X, Onoue T, Katayama Y, Okauchi T, Hayashinaka E, Cui Y, Wada Y, Suzuki M, Maeda K, Kusuhara H, Sugiyama Y, Watanabe Y.
- Journal Title
  
  J. Pharmacol. Exp. Ther.
  
  Volume: 347 Pages: 193-202
- DOI
  10.1124/jpet.113.206425
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23136101, KAKENHI-PROJECT-24229002, KAKENHI-PROJECT-24659574, KAKENHI-PROJECT-25242070, KAKENHI-PROJECT-25460147
[Journal Article] PET トレーサー合成基盤を刷新する高速メチル化反応 : プロスタグランジン受容体の可視化2005
- Author(s)
  鈴木正昭
- Journal Title
  
  科学と生物 43
  
  Pages: 804-808
- Data Source
  KAKENHI-PROJECT-13NP0401
[Journal Article] Rapid methylation on carbon frameworks leading to the synthesis of a PET tracer capable of imaging a novel CNS-type prostacyclin receptor in living human brain2004
- Author(s)
  M.Suzuki
- Journal Title
  
  Trends in Analytical Chemistry 23・8
  
  Pages: 595-607
- Data Source
  KAKENHI-PROJECT-13NP0401
[Journal Article] Positron Emission Tomography (PET)法による生体の分子イメージング研究と創薬・医療への応用2004
- Author(s)
  鈴木正昭
- Journal Title
  
  生物物理 44・6
  
  Pages: 265-270
- Data Source
  KAKENHI-PROJECT-13NP0401
[Journal Article] ミニレビュー脳を探る分子プローブ設計:ヒト脳内IP_2受容体の分子イメージング2004
- Author(s)
  鈴木正昭
- Journal Title
  
  日本神経精神薬理学雑誌 24
  
  Pages: 221-229
- Data Source
  KAKENHI-PROJECT-13NP0401
[Presentation] Synthesis of highly-qualified 11C-labeled (R,S)-isoproterenol aimed at a clinical study2017
- Author(s)
  Ikenuma H, Koyama H, Kimura Y, Abe J, Kawasumi K, Ogata A, Kato T, Ito K, Suzuki M.
- Organizer
  The 12th Asia Oceania Congress of Nuclear Medicine and Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04269
[Presentation] 臨床研究を目的とした11C標識化(R,S)-イソプロテレノールの高効率合成法の開発2017
- Author(s)
  池沼　宏、古山浩子、木村泰之、阿部潤一郎、川角保広、小縣　綾、加藤隆司、伊藤健吾、鈴木正昭
- Organizer
  第57回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-17H04269
[Presentation] 認知症治療薬としてのイソプロテレノールの小動物PETを用いたラット脳内移行性の検討2017
- Author(s)
  小縣　綾、木村泰之、池沼　宏、古山浩子、関千江、山田貴史、鈴木正昭、加藤隆司、伊藤健吾
- Organizer
  第57回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-17H04269
[Presentation] Brain penetration of isoproterenol as a drug of dementia measured in rats with a micro-PET2017
- Author(s)
  Ogata A, Kimura Y, Ikenuma H, Koyama H, Seki C, Yamada T, Suzuki M, Kato T, Ito K.
- Organizer
  The 12th Asia Oceania Congress of Nuclear Medicine and Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04269
[Presentation] The Chemistry to Life Science: Highly Potentiated C-C Couplings2016
- Author(s)
  Masaaki Suzuki
- Organizer
  King’s College London-Nagoya University Workshop in Cancer and Neuroscience
- Place of Presentation
  Nagoya University
- Year and Date
  2016-03-10
- Invited
- Data Source
  KAKENHI-PROJECT-25242070
[Presentation] 疾患対応新規PET分子プローブの革新的合成法と医学生物学的活用2015
- Author(s)
  鈴木正昭
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋市
- Year and Date
  2015-10-08
- Invited
- Data Source
  KAKENHI-PROJECT-25242070
[Presentation] Rh(I)-mediated rapid [11C]carboxylation using [11C]CO2 and organoborate at atmospheric pressure2015
- Author(s)
  Miki Goto, Sachi Kurai, Ryo Yamamoto, Tomozumi Kanamitsu, Masaaki Suzuki, Yasuyohi Watanabe, Hisashi Doi
- Organizer
  The International Chemical Congress of Pacific Basin Societies 2015
- Place of Presentation
  Honolulu, Hawaii, USA
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25242070
[Presentation] Evaluation of TlOH Effects for Pd0-Mediated Cross-Coupling of Methyl Iodide and Excess Boronic Acid Esters toward 11C-Incorporated PET Tracer Synthesis, Research area (10) Bench to Bedside2015
- Author(s)
  Hiroko Koyama, Hisashi Doi, Masaaki Suzuki
- Organizer
  The International Chemical Congress of Pacific Basin Societies 2015
- Place of Presentation
  Honolulu, Hawaii, USA
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25242070
[Presentation] 11C-labeling of the C(1)-C(10) dihydroxy acid moiety for the study on the synthesis of kulokekahilide-2 PET tracer2015
- Author(s)
  Chunguang Han, Hisashi Doi, Jyunji Kimura, Yoichi Nakao, Masaaki Suzuki
- Organizer
  The International Chemical Congress of Pacific Basin Societies 2015
- Place of Presentation
  Honolulu, Hawaii, USA
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25242070
[Presentation] A knack and pitfalls in the development of the novel 11C-labeled PET tracer synthesis2014
- Author(s)
  Misato Takashima, Miho Shukuri, Mikako Ogawa, Yasuomi Ouchi, Hirotaka Onoe, Masaaki Suzuki, Yasuhiro Magata
- Organizer
  The 15th Conference of Peace through Mind/Brain Science
- Place of Presentation
  Hamamatsu
- Data Source
  KAKENHI-PROJECT-25242070
[Presentation] 脳内aromataseとヒトの性格・気質との関連―PET 研究2014
- Author(s)
  高橋佳代、細谷孝充、高島忠之、田中雅彰、石井聰、中富康仁、田沢周作、高橋和弘、土居久志、和田康弘、鈴木正昭、尾上浩隆、渡辺恭良
- Organizer
  日本分子イメージング学会　第9回学会総会・学術集会
- Place of Presentation
  千里ライフサイエンスセンター
- Data Source
  KAKENHI-PROJECT-25242070
[Presentation] Imaging of cyclooxygenase-1 in activated microglia by PET with S-enantiomer of 11C-ketoprofen-methyl ester2013
- Author(s)
  Miho Shukuri, Aya Mawatari, Masahiro Ohno, Hisashi Doi, Masaaki Suzuki, Yasuyoshi Watanabe, Hirotaka Onoe
- Organizer
  EANM'13-Annual Congress of the European Association of Nuclear Medicine
- Place of Presentation
  France・Lyon
- Data Source
  KAKENHI-PROJECT-25242070
[Presentation] [11C]標識NSAIDsによるシクロオキシゲナーゼのPETイメージング2013
- Author(s)
  尾上浩隆、宿里充穂、鈴木正昭、渡辺恭良
- Organizer
  第53回日本核医学会学術総会
- Place of Presentation
  福岡・福岡国際会議場
- Data Source
  KAKENHI-PROJECT-25242070

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Suzuki Masaaki 鈴木 正昭

鈴木 正昭 スズキ マサアキ

SUZUKI Masaaki 鈴木 正昭

鈴木 正明 スズキ マサアキ

Research Projects

Research Products

Co-Researchers

PET imaging of microglia, a novel drug target for neurodegenerative diseasesOngoing

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Synthesis of 11C-labeled acyclic retinoids with high brain permeabilityOngoing

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Review Section

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PET microdose study for finding appropriate dose of isoproterenol as a disease modifying treatment of dementiaOngoing

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Development of PET probes of neuroprotective molecular components in oriental medicinesPrincipal Investigator

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生物新機能と創薬をめざす生体内分子科学Principal Investigator

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生体内分子科学Principal Investigator

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Biological Functions and Designed Probe CompoundsPrincipal Investigator

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Development of Anti-apoptoic Drugs for Neuronal Cells and Distribution Analysis in BrainPrincipal Investigator

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Novel PET Tracers for Prostaglandin ReceptorsPrincipal Investigator

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標的分子の構造情報に基づく分子設計及び有機合成Principal Investigator

Principal Investigator

Suzuki Masaaki 鈴木正昭

鈴木正昭スズキマサアキ

SUZUKI Masaaki 鈴木正昭

鈴木正明スズキマサアキ