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TANIGUCHI Takashi
谷口 隆之
Connect your ORCID iD
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Researcher Number
10111957
Affiliation (based on the past Project Information)
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2009 – 2010: Kyoto Pharmaceutical University, 薬学部, 教授
2004 – 2006: Kyoto Pharmaceutical University, Pharmaceutical Sciences, Professor, 薬学部, 教授
2003: 京都薬科大学, 薬学部・病態生理学, 教授
1998 – 2001: 京都薬科大学, 薬学部・病態生理学, 教授
1995 – 1996: 京都薬科大学, 薬学部・病態生理学, 教授
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1994: 京都薬科大学, 薬学部・生物学, 教授
1992 – 1994: 京都薬科大学, 薬学部, 教授
1988 – 1990: 京都薬科大学, 薬学部, 教授
1987: Same to above, 医学部, 講師
1986: 京都大学, 医学部, 助手
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Review Section/Research Field
Principal Investigator
General pharmacology
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応用薬理学・医療系薬学
/
Biological pharmacy
/
General pharmacology
Except Principal Investigator
General pharmacology
/
Cerebral neurosurgery
Keywords
Principal Investigator
ミクログリア / ラット / 海馬 / アストロサイト / アルツハイマー病 / Microglia / アルツハイマ-型痴呆脳 / グルタミン酸受容体 / protein kinase C / 膜分画
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/ 低酸素負荷 / 神経細胞死 / 低酸素 / 酸化ストレス / カイニン酸 / Brain ischemia / Astrocyte / 神経保護作用 / Alzheimer's disease / NMDA受容体 / ^3H-glutamate結合部位 / ^3H-TCP結合部位 / 前頭葉 / ^3HーPDBu結合 / 可溶性分画 / 側頭葉 / ^3HーPDBu結合実験 / 細胞質分画 / 核分画 / ラット海馬 / 脳・免疫協関 / 主要組織適合性複合体 / MHC class 1 / MHC class 2 / グルタミン酸 / NMDA型受容体 / non-NMDA型受容体 / 一酸化窒素合成酵素 / 一酸化炭素(CO) / ヘムオキシゲナーゼ-1(HO-1) / 一酸化窒素(NO) / 誘導型NO合成酵素(iNOS) / 主要組織適合性遺伝子複合体(MHC) / Bcl-2ファミリー / プロテインキナーゼA / プロテインキナーゼC / 一酸化窒素 / p53蛋白質 / アポトーシス / アミロイドβ / ガランタミン / 貪食 / allosterically Potentiating ligand / ニコチン性アセチルコリン受容体 / トランスジェニックマウス / 神経原線維変化 / シナプス破綻 / 細胞骨格タンパク質 / アクチン重合 / 部検脳 / ウサギ虹彩括約筋 / タキキニン受容体 / substanceP / neurokininA / イノシトールリン脂質代謝回転 / 結合実験 / 経壁電気刺激 / 非コリン性非アドレナリン性反応 / 脳虚血 / ヘムオキシゲナーゼ / ビリベルジン / 非ステロイド性抗炎症薬(NSAID) / 一酸化窒素合成酵素(iNOS) / プロティンキナーゼC / Peroxisome Proliferator-activated receptor-γ(PPARγ) / 一過性前脳虚血 / Hippocampus / Heme Oxygenase / Oxidative Stress / Bilverdin / Nonsteroidal Anti-inflammatory Drug (NSAID) / 脳梗塞モデル / 中大脳動脈閉塞 / ヘムオキシゲナーゼ1 / α-シヌクレイン / チトクロームc / ヘムオキシゲナーゼ-1 / 中大脳動脈閉塞-再灌流 / Focal Ischemia / Occlusion of the middle cerebral artery / Neurodegeneration / α-Synuclein / Heme Oxygenase-1 (HO-1) / Neuroprotection / アミロイドβクリアランス / ファゴサイトーシス / 中大脳動脈閉塞ラットモデル / サイトカイン / 熱ショック蛋白質-90 / Astrocytes / Amyloid-β clearance / Phagocytosis / Rat brain focal ischemia / Cytokines / Neuroprotective effects / 神経ネットワーク / 脳梗塞 / パーキンソン病 / 神経形態形成 / 胚性幹細胞 / 移植 / 神経幹細胞 / ドパミンニューロン / 黒質-線条体 / 視床下核 / Neuronal network / Parkinson's disease / Neuronal morphology / Mouse embryonic stem cells / Transplantation
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Except Principal Investigator
Parkinson's disease / Recombinant brain-derived neurotrophic factor / Nerve growth factor / Neurotoxicity / Neurodegenerative disease / Cerebral ischemia / Brain‐Derived Neurotrophic Factor(BDNF) / 1‐Methy1‐4‐Pheny1‐1、2、3、6‐Tetrahydropyridine(MPTP) / Monkey / 脳血管スパスム / 内皮細依存性収縮 / 内皮細胞由来TX【A_2】様物質 / VOC / ROC / 脈動脈 / 受容体作動性Caチャンネル / Brain derived neurotrophic factor / 脳虚血 / 神経変性疾患 / 脳血管〓縮物質 / 内皮細胞由来血管収縮物質 / TXA2-様物質 / 脳血管攣縮 / クモ膜下出血 / 内皮細胞依存性収縮因子 / TX【A_2】様物質 / 脳脊髄液 / 脳血管 / 内皮細胞 / Subarachnoid hemorrhage / Cerebrospinal fluid / Endothelium-dependent contraction / 強心性ポリペプチド / ハナガササンゴ / ゴニオボラ トキシン / Naチャネル / 不活性化過程の抑制 / イワスナギンチャク / パリトキシン / cDNAのクローニング / 強心性ポリペブチド / ゴニオポーラトキシン / Cardiotonic marine toxins / Goniopora toxin / palytoxin / positive inotropic action / Prolongation of action potential / Sodium channel / Inactivation process
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Research Projects
(
20
results)
Co-Researchers
(
11
People)
Project Start Year (Newest)
Project Start Year (Oldest)
骨髄由来細胞の脳障害部位へのホーミング機能を利用した神経保護薬送達法樹立への挑戦
Principal Investigator
Principal Investigator
谷口 隆之
Project Period (FY)
2009 – 2010
Research Category
Grant-in-Aid for Challenging Exploratory Research
Research Field
General pharmacology
Research Institution
Kyoto Pharmaceutical University
Reconstruction of neuronal network in neurodegenerative disorders
Principal Investigator
Principal Investigator
TANIGUCHI Takashi
Project Period (FY)
2005 – 2006
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Biological pharmacy
Research Institution
Kyoto Pharmaceutical University
Glial Cell Therapy Using Neuroprotective effects of Glia
Principal Investigator
Principal Investigator
TANIGUCHI Takashi
Project Period (FY)
2003 – 2004
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Biological pharmacy
Research Institution
Kyoto Pharmaceutical University
The Study Glial Regeneration and Neuroprotection on Brain Ischemic Model
Principal Investigator
Principal Investigator
TANIGUCHI Takashi
Project Period (FY)
2000 – 2001
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
応用薬理学・医療系薬学
Research Institution
Kyoto Pharmaceutical University
プロテインキナーゼ作用薬によるBcl-2蛋白質の発現調節の研究
Principal Investigator
Principal Investigator
谷口 隆之
Project Period (FY)
1998
Research Category
Grant-in-Aid for Scientific Research on Priority Areas (A)
Research Institution
Kyoto Pharmaceutical University
The Study of Heme Oxygenase Induction in the Hippocampus by Brain Ischemia and Hypoxia.
Principal Investigator
Principal Investigator
TANIGUCHI Takashi
Project Period (FY)
1998 – 1999
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
応用薬理学・医療系薬学
Research Institution
Kyoto Pharmaceutical University
脳における生理活性分子としての一酸化炭素の機能解析
Principal Investigator
Principal Investigator
谷口 隆之
Project Period (FY)
1996
Research Category
Grant-in-Aid for Exploratory Research
Research Field
General pharmacology
Research Institution
Kyoto Pharmaceutical University
低酸素負荷により誘導される脳神経細胞死の神経薬理学的解析
Principal Investigator
Principal Investigator
谷口 隆之
Project Period (FY)
1995
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
General pharmacology
Research Institution
Kyoto Pharmaceutical University
脳由来神経栄養因子による神経変性疾患の治療
Principal Investigator
TSUKAHARA Tetsuya
Project Period (FY)
1994
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
National Cardiovascular Center Research Institute
低酸素負荷ラット海馬における選択的脳神経細胞死と免疫系の応答
Principal Investigator
Principal Investigator
谷口 隆之
Project Period (FY)
1994
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
General pharmacology
Research Institution
Kyoto Pharmaceutical University
海馬CA3、歯状回領域における選択的神経細胞死の発生機序解明
Principal Investigator
Principal Investigator
谷口 隆之
Project Period (FY)
1993
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
General pharmacology
Research Institution
Kyoto Pharmaceutical University
Treatment of Neurodegenerative disease with recombinent cells
Principal Investigator
TSUKAHARA Tetsuya
Project Period (FY)
1992 – 1994
Research Category
Grant-in-Aid for Developmental Scientific Research (B)
Research Field
Cerebral neurosurgery
Research Institution
National Cardio Vascular Center Research Institute
アルツハイマ-型痴呆脳における受容体の変動
Principal Investigator
Principal Investigator
谷口 隆之
Project Period (FY)
1990
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Kyoto Pharmaceutical University
低酸素負荷によるラット脳内カルシウム依存性タンパクリン酸化酵素の変動
Principal Investigator
Principal Investigator
谷口 隆之
Project Period (FY)
1990
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
General pharmacology
Research Institution
Kyoto Pharmaceutical University
アルツハイマ-型痴呆脳における受容体の変動
Principal Investigator
Principal Investigator
谷口 隆之
Project Period (FY)
1989
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Kyoto Pharmaceutical University
ウサギ虹彩括約筋のタキキニン性神経伝達と受容体
Principal Investigator
Principal Investigator
谷口 隆之
Project Period (FY)
1988
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
General pharmacology
Research Institution
Kyoto Pharmaceutical University
血管スパスムにおけるCaイオン動態と役割:受容体作動性Caイオンチャンネル
Principal Investigator
藤原 元始
Project Period (FY)
1987
Research Category
Grant-in-Aid for Special Project Research
Research Institution
Kyoto University
ヒト脳血管スパスムにおけるCaイオンの動態と役割
Principal Investigator
FUJIWARA Motohatsu
Project Period (FY)
1986
Research Category
Grant-in-Aid for Special Project Research
Research Institution
Kyoto University
Mechanisms of action of cardiotonic polypeptide marine toxins on sodium channels
Principal Investigator
FUJIWARA Motohatsu
Project Period (FY)
1986 – 1987
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
General pharmacology
Research Institution
Kyoto University
Expoloration of spasmogenic factors and its antagonist for cerebrovasculor spasm
Principal Investigator
FUJIWARA Motohatsu
Project Period (FY)
1985 – 1987
Research Category
Grant-in-Aid for Developmental Scientific Research
Research Field
General pharmacology
Research Institution
Kyoto University
# of Projects (Dsc)
# of Projects (Asc)
1.
FUJIWARA Motohatsu
(90025536)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
2.
MIWA Soichi
(40157706)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
3.
NARUMIYA Shu
(70144350)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
4.
KURAHASHI Kazuyoshi
(10025653)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
5.
福永 玲子
(50189966)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
6.
亀山 正邦
(30101231)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
7.
TSUKAHARA Tetsuya
(30217278)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
8.
OKAMOTO Shinichiro
(40160717)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
9.
SHIMOHARA Shun
(60235687)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
10.
MURAMATSU Ikunobu
(10111965)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
11.
HATANAKA Shoichi
(30142300)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
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