SUDA TATSUO 須田立雄

… Alternative Names

Researcher Number	90014034
Affiliation (based on the past Project Information) *help	2015 – 2016: 埼玉医科大学, 医学部, 客員教授 2015: 埼玉医科大, 医学部, 客員教授 2013: 埼玉医科大学, 医学部, 客員教授 2006: 埼玉医科大学, 医学部, 客員教授 2002 – 2005: 埼玉医科大学, 医学部, 教授 … More
Review Section/Research Field	Principal Investigator Functional basic dentistry / Orthopaedic surgery Except Principal Investigator Functional basic dentistry / Morphological basic dentistry / Orthopaedic surgery / Pathological medical chemistry / Hematology / Functional basic dentistry / Surgical dentistry
Keywords	Principal Investigator 破骨細胞 / 活性型ビタミンD / 骨芽細胞 / 骨吸収 / M-CSF / bone resorption / ODF / 副甲状腺ホルモン / osteoclast / カルシトニン … More Except Principal Investigator 骨芽細胞 / 破骨細胞 / 骨吸収 / 活性型ビタミンD / Osteoblast / Osteoclast / osteoblast / BMP / OPG / osteoclast / M-CSF / ODF / RANK / IL-1 / 分化 / Bone resorption / 分化誘導療法 / 血小板 / ビタミンD / GM-CSF / 骨髄間質細胞 / bone resorption / p60^<c-src> / 骨粗鬆症 / 軟骨細胞 / chondrocyte / RT-PCR / 副甲状腺ホルモン / RANKL / D因子 / シアロ糖化合物 / PI代謝回転阻害剤 / 分化誘導剤 / 破骨細胞活性化因子 / 生理活性 / 骨形成 / 蛋白質 / 巨核球 / 骨代謝 / ハービマイシン / オステオポンチン / LIF / マクロファ-ジ / Osteopontin / 1α,25(OH)_2D_3 / MーCSF / 大理石骨病 / macrophage / ODC / 1alpha, 25-dihydroxyvitamin D_3 / C3 / 1alpha,25(OH)_2D_3 / op / opマウス / oc / ocマウス / c-src / osteoporosis / シクロオキシゲナーゼ / アラキドン酸 / プロスタグランジン / cyclooxygenase / 骨細胞 / 培養細胞 / in situ hybridization / In situ hybridization / bone formation / vitamin D / Hedgehog / 腎臓 / ネフロン / 24-水酸化酵素 / ビタミンD受容体 / カルシウム / parathyroid hormone / 1alpha-hydroxylase / 24-hydroxylase / E-64 / in vitro / in vivo / gp130 / IL-6 / IL-11 / 遺伝子欠損マウス / 骨誘導因子 / platelet / アルキルエーテル非燐脂質 / 分化誘導療法補強剤 / 熱ショック蛋白質 / 倍数性骨髄性白血病株細胞 / 活性化酸素 / ピリミジンヌクレオシド化合物 / 蛋白リン酸化酵素阻害剤 / ミオシンL鎖キナ-ゼ阻害剤 / MDS由来細胞株 / AraC感受性 / アポプト-シス / ラット骨髄前脂肪細胞株RECAー16 / 脂質性合成シアロ糖化合物 / 特異的チロシンキナ-ゼ阻害物質 / 抗癌剤排出性P糖蛋白 / 活性型ビタミンD3 / トランスフォ-ミング増殖因子(TGF)β / 造血因子MーCSF / インスリン受容体βサブユニット自己リン酸化反応 / 糖鎖含有リコンビナントD因子 / チロシンキナーゼ阻害剤 / 非リン酸化RB遺伝子産物 / 糖転移酵素系 / エンドヌクレアーゼ / アポプトーシス / フラバノン化合物デスマール / 生体分子 / 細胞・組織 / 糖代謝 / エピジェネティック / 転写因子 / ロコモティブ / エピジェネティクス / Pax6 / 遺伝子調節 / 核酸関連化合物 / ビタミンD_3誘導体 / GーCSF / ブロメライン / インターロイキン6 / TNF 変異体 / ガングリオシド類縁体 / 赤芽球分化因子 / エリトロポエチン / ILー6 / インタ-ロイキン1 / 細胞融合 / GMーCSF / Iγ-4 / Iγ-6 / Interleukin 1 / Macrophage fusion / Lalpha, 25 (OH) _2D_3 / マクロファ-ジコロニ-刺激因子 / 骨吸収調節因子 / 骨髄由来ストロ-マ細胞 / monocyte / 1alpha, 25 (OH) _2D_3 / osteopetosis / cell-cell interaction / 小腸 / Ca吸収 / ポリアミン / プトレッシン / ポリアミン合成阻害剤 / CaーATPase / ポリアミン酸化酵素 / Intestine / Ca transport / polyamine / putrescine / Ca-ATPase / villus / 歯槽骨吸収 / 概日リズム / 局所的骨吸収因子 / オステオカルシン / 概口リズム / 骨吸収病態モデル / bisphosphonate / カテプシンD / 扁平上皮癌株細胞 / 病態モデル / 細胞内プロテア-ゼ / 骨吸収促進物質 / 組織再生法 / Alveolar Bone Resorption / Bone Resorption / Circadian rhythm / Bone Resorption Factor / Osteocalcin / 補体第3成分 / C3レセプター / マウス補体第3成分 / 肝臓 / 116kD / ILー1 / complement / C3 receptor / マクロファ-ジコロニ-剌激因子 / osteopetrosis / macrophage colony stimulating (M-CSF) / 脂肪細胞 / 脂質合成 / リン脂質 / トリグリセリド / 前脂肪細胞 / デキサメタゾン / 脂質代謝 / ホスファチジルコリン / adipocyte / adipogenesis / phospholipids / preadipocyte / triacylglycerol / vitamin D derivatives / PAFアセチルハイドロラーゼ / P450(11β, aldo) / アルドステロン合成酵素 / PGE2受容体サブタイプ / 1α,25-(OH)2ビタミンD-24水酸化酵素 / ミッドカイン / PAF受容体 / P450(11β,aldo) / シクロオキシゲナーゼ-2(COX-2) / コルチコステロン合成酵素 / PGE_2受容体サブタイプ / 1α,25-(OH)_2ビタミンD-24水酸化酵素 / PAF受容体遺伝子 / PAF / ステロイド産生 / レチノイン酸 / ホスホリパーゼA_2 / リポキシゲナーゼ / PAF acetylhydrolase / P450 (11beta, aldo) / aldosterone synthetase / PGE2 receptor subtypes / 1alpha, 25-dihydroxyvitamin D3-24-hydroxylase / midkine / PAF receptor / In sltu hrbridization / レーザー顕微鏡 / osteocyte / cell culture / 筋細胞 / muscle / 波状縁 / 明帯 / ポドソーム / カルシトニン / PI-3キナーゼ / 低分子量G蛋白rho / Pl-3キナーゼ / Focal adhesion kinase / ポドソーム形成 / 吸収窩 / ruffled border / clear zone / podosme / calcitonin / PI-3 kinase / small GTP binding protein rho / 補体第3因子 / 転写調節 / 骨髄ストローマ細胞 / ビタミンD欠乏 / 骨 / 補体第3因子(C3) / C3遺伝子 / complement 3 / stromal cells / bone marrow / bone / 筋芽細胞 / 間葉系細胞 / 骨形成因子(BMP) / 筋肉 / ostepblast / myoblast / vitamin D receptor / kidney / mRNA / インテグリン / RGDペプチド / カテプシン / 微細構造 / 細胞培養 / Integrin / RGD peptide / Cathepsin / Ultrastructure / IL-6レセプター / 慢性関節リウマチ / 可溶性IL-6レセプター / トランスジェニックマウス / 滑液 / IL-6 receptor / osteoclasts / osteoblasts / rheumatoid arthritis / インターロイキン1 / ホスホリパーゼA2 / 血小板由来増殖因子 / プロスタグランジンE / インターロイキン-1 / ホスホリッパーゼA_2 / prostaglandin / interleukin-1 / phospholipase A2 / platelet-derived growth factor / 1α-水酸化酵素 / シトクロムP-450 / シトクロムP450 / 近位尿細管 / proximal convoluted tubules / cytochrome P450 / vitamin D receptors / degenerate-PCR / インターロイキン18 / インターフェロンγ / Tリンパ球 / Interleukin 18 / Interferon gamma / T-lymphocyte / Gene targetting mouse / 1L-1 / 破骨細胞分化因子(ODF) / シグナル伝達 / osteoprotegerin(OPG) / osteoclastogenesis inhibitory factor(OCIF) / osteoclast activiting factor / 女性ホルモン / Bリンパ球 / エストロゲンレセプター / 骨髄造血 / estrogen / B lymphocyte / estrogebn receptor / 破骨細胞分化因子 / 破骨細胞形成抑制因子 / 骨随間質細胞 / マクロファジーコロニー刺激因子 / TNF / 1α, 25(OH)_2D_3 / PTH / 炎症性サイトカイン / TNFα / 細胞内Ca / Inflammatory cytokines / Calcium / Osteoporosis / 胞体突起形成(prpplatelet formation, PPF) / トロンボポエチン(TPO) / PPFコミットメント因子(PCF) / ヒト線維芽細胞 / セラミック培養 / ユビキチン / 胞体突起形成 / proplatelet formation (PPF) / megakaryocytes / proplatelet_formation / PPF commitment factor, PCF / human fibroblasts / ceramic culture system / ubiquitin / 骨芽細胞分化 / 生体成分 / 血清 / serum / protein / osteoblast differentiation / 分化誘導因子 / 骨吸収作用 / 肺胞マクロファージ / 増殖 / DIF / netrin-4 / semaphorin 3A / 血管内皮細胞 / 骨・神経・血管 / 骨減少症 / ネットワーク機構 / 神経芽細胞 / ネットワーク / 遺伝子網羅的解析 / 遊走能 / 分化能 / CDK6 / 血管系 / 神経系 Less

Molecular mechanisms of nerve-vessel-bone network
- Principal Investigator
  
  SATO Tsuyoshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Saitama Medical University
Molecular insights of the crosstalk between locomotive and metabolic syndromes
- Principal Investigator
  
  Matsumoto Masahito
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Saitama Medical University
巨核球・血小板に由来する骨形成促進因子の単離・同定に基づく新しい研究領域の開拓
- Principal Investigator
  
  片桐岳信
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Saitama Medical University
Isolation and identification of bone morphogentic protein and its potentiator from bovine serum
- Principal Investigator
  
  KATAGIRI Takenobu
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Saitama Medical School
A study of cross-talk between the expression mechanisms of osteoclast differentiation factor (ODF) and osteoclastogenesis inhibitory factor (OCIF)Principal Investigator
- Principal Investigator
  
  SUDA Tatsuo
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Saitama Medical School
Studies on novel cytokines produced by human embryonic fibroblasts.
- Principal Investigator
  
  HIGASHIO Kanji
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Saitama Medical School
破骨細胞の融合機構とその生理的意義の解明
- Principal Investigator
  
  高橋直之
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
The physiological role of osteoclast differentiation factor.
- Principal Investigator
  
  UDAGAWA Nobuyuki
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
Study on signal transduction in osteoclastogenesis for the development of anti-osteoporosis drugs.
- Principal Investigator
  
  TAKAHASHI Naoyuki
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
The roles of nuclear transcription factors in calcium homeostasisPrincipal Investigator
- Principal Investigator
  
  SUDA Tatsuo
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
Study on osteoclast activiting factor expressed by osteoblasts/stromal cells
- Principal Investigator
  
  TAKAHASHI Naoyuki
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
Pathogenesis of osteoporosis : role of estrogen in bone metabolism
- Principal Investigator
  
  MIYAURA Chisato
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Tokyo University of Pharmacy and Life Science
ヒトPTH受容体遺伝子の導入によるヒト破骨細胞形成系の確立Principal Investigator
- Principal Investigator
  
  須田立雄
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
Mechanism of osteoclastogenesis inhibitory action by interleukin 18
- Principal Investigator
  
  UDAGAWA Nobuyuki, 宇田川信之
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
Pathogenesis of bone loss due to estrogen deficiency : Relationship between increased B-lymphopoiesis and bone resorption.Principal Investigator
- Principal Investigator
  
  SUDA Tatsuo
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
Regulation of PGE synthesis by activated cytosolic phospholipase A2 and induced cyclooxygenase-2 in osteoblasts.
- Principal Investigator
  
  MIYAURA Chisato
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
Mechanism of regulation of vitamin D metabolism at molecular level.
- Principal Investigator
  
  SHINKI Toshimasa, 新木敏正
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
Development of bone metabolism improvement medicines based on the analysis of signal transductionPrincipal Investigator
- Principal Investigator
  
  SUDA Tasuo
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
Analysis of gp130-induced signals which regulate osteclast formation and function
- Principal Investigator
  
  TAKAHASHI Naoyuki
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
Role of BMPs in differentiation process of osteoblasts, chondrocytes and muscle cells
- Principal Investigator
  
  YOSHIKI Susaku
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Showa University
Molecular mechanisms of osteoporosis induced by estrogen deficiency.Principal Investigator
- Principal Investigator
  
  SUDA Tatsuo
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
Role of vitamin D and parathyroid hormone on vitamin D metabolism in the kidney.
- Principal Investigator
  
  SHINKI Toshimasa
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
Localization and Functions of Integrins and Proteinase in Osteoclasts
- Principal Investigator
  
  SASAKI Takahisa
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Showa University
A study for gene expression of synthetic enzymes and receptors for lipid biofactors
- Principal Investigator
  
  ICHIKAWA Atsushi
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  KYOTO UNIVERSITY
Study of the mechanism of bone formation using morphological and functional analyzes
- Principal Investigator
  
  YOSHIKI Shusaku
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Showa University
Study for differentiation process of osteoblasts
- Principal Investigator
  
  YAMAGUCHI Akira
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Showa University
Analysis of signaling pathways involved in polarization of osteoclasts.
- Principal Investigator
  
  TAKAHASHI Naoyuki
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
Development of reliable screening systems for drugs which regulate bone resorption : In vitro assay systems for osteoclast formation and function.Principal Investigator
- Principal Investigator
  
  SUDA Tatsuo
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
Production and biological roles of the third component of complement in bone.
- Principal Investigator
  
  MIYAURA Chisato
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
細胞分化誘導剤の臨床応用に関する基礎的研究
- Principal Investigator
  
  斉藤政樹
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Jichi Medical University
Molecular aspects of vitamin D metabolism and actionPrincipal Investigator
- Principal Investigator
  
  SUDA Tatsuo
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
細胞分化誘導剤の臨床応用に関する基礎的研究
- Principal Investigator
  
  斎藤政樹
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Jichi Medical University
Cloning of proteins produced by osteoblastic cells in response to 1alpha,25(OH)_2D_3.
- Principal Investigator
  
  ABE Etsuko
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
Study on Interaction between Osteoclast Progenitors and Osteoblastic Cells in Osteoclast Development.
- Principal Investigator
  
  TAKAHASHI Naoyuki
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
Role of vitamin D_3 on differentiation of bone marrow-derived stromal cells.
- Principal Investigator
  
  SHINKI Toshimasa
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
Studies of the Etiology and Therapeutic Approach of Alveolar Bone Resorption
- Principal Investigator
  
  OGURA Hideaki
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Tokyo Medical and Dental University
Basic study on the risk factors of osteoporosis.Principal Investigator
- Principal Investigator
  
  SUDA Tatsuo
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
新しい分化誘導療法剤の開発と分化誘導療法の基礎的研究
- Principal Investigator
  
  穂積本男
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Research Institute for Clinical Oncology, Saitama Cancer Center
The Role of Cytokines in Bone Resorption and Bone Formation
- Principal Investigator
  
  ABE Etsuko
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
Rolo of Osteoblastic Cells in Osteoclast Development.
- Principal Investigator
  
  TAKAHASHI Naoyuki
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
Role of Putrescine in Vitamin D-Dependent Intestinal Cell Differentiation.
- Principal Investigator
  
  SHINKI Toshimasa
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
Establishment of the screening methods for bone-resorbing factors using in vitro osteoclast formation system.Principal Investigator
- Principal Investigator
  
  SUDA Tatsuo
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
新しい分化誘導療法剤の開発と分化誘導療法の基礎的研究
- Principal Investigator
  
  穂積本男
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Research Institute for Clinical Oncology, Saitama Cancer Center
Two step model for the fusion of macrophages induced by 1alpha, 25-dihydroxyvitamin D_3Principal Investigator
- Principal Investigator
  
  SUDA Tatsuo
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
新しい分化誘導剤の開発と分化誘導療法の基礎的研究
- Principal Investigator
  
  穂積本男
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Research Institute for Clinical Oncology, Saitama Cancer Center
Mechanisms of Osteoclast Formation
- Principal Investigator
  
  ABE Etsuko
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
Development of new assay systems for examining the relation between osteoblasts and osteoclasts, and identification of new factors controlling bone metabolismPrincipal Investigator
- Principal Investigator
  
  SUDA Tatsuo
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University, School of Dentistry
活性型ビタミンDによる細胞分化と発癌プロモーションの制御Principal Investigator
- Principal Investigator
  
  須田立雄
- Project Period (FY)
  1985
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Showa University
Mechanisms of Fusion of Macrophages Induced by 1 ,25(OH)_2D_3Principal Investigator
- Principal Investigator
  
  SUDA Tatsuo
- Project Period (FY)
  1985 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
活性型ビタミンDによる細胞分化と発癌プロモーションの制御Principal Investigator
- Principal Investigator
  
  須田立雄
- Project Period (FY)
  1984 – 1986
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Showa University

All 2015 2014 2013 2005 2004

All Journal Article Presentation Book Patent

[Book] Vitamin D, 2^<nd> edition (ed. Feldman, Pike, Glorieux)2005
- Author(s)
  Yasuda B, Higashio K, Suda T
- Publisher
  Elsevier
- Data Source
  KAKENHI-PROJECT-15390465
[Journal Article] Donepezil prevents RANKL-induced rapid bone loss in vivo via inhibiting osteoclast differentiation with the downregulation of acetylcholinesterase: a possible mechanism of fracture prevention in Alzheimer’s disease.2015
- Author(s)
  Sato T, Enoki Y, Sakamoto Y, Yokota K, Okubo M, Matsumoto M, Hayashi N, Usui M, Kokabu S, Mimura T, Nakazato T, Araki N, Fukuda T, Okazaki Y, Suda T, Takeda S, Yoda T.
- Journal Title
  
  Heliyon
  
  Volume: 1 Pages: 1-20
- DOI
  10.1016/j.heliyon.2015.e00013
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462380, KAKENHI-PROJECT-26870543
[Journal Article] Netrin-4 derived from murine vascular endothelial cells inhibits osteoclast differentiation in vitro and prevents bone loss in vivo.2014
- Author(s)
  Matsumoto, Masahiko Okubo, Keisuke Nakashima, Masayuki Yamato, Teruo Okano, Toru Fukuda, Dai Chida, Yuuki Imai, Hisataka Yasuda, Tatsuji Nishihara, Masumi Akita, Hiromi Oda, Yasushi Okazaki, Tatsuo Suda, Tetsuya Yoda
- Journal Title
  
  FEBS Letters
  
  Volume: 588 Pages: 2262-2269
- DOI
  10.1016/j.febslet.2014.05.009
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25253090, KAKENHI-PROJECT-26293432
[Journal Article] The Paired-box Domain Transcription Factor Pax6 Binds to the Upstream Region of the TRAP Gene Promoter and Suppresses RANKL-induced Osteoclast Differentiation.2013
- Author(s)
  Kogawa M, Hisatake K, Atkins GJ, Findlay DM, Enoki Y, Sato T, Gray PC, Kanesaki-Yatsuka Y, Anerson PH, Wada S, Kato N, Fukuda A, Katayama S, Tsujimoto M, Yoda T, Suda T, Okazaki Y, Matsumoto M
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 288 Pages: 31299-312
- DOI
  10.1074/jbc.m113.461848
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460354, KAKENHI-PROJECT-25462380
[Journal Article] Vitamin D and osteoclastogenesis2005
- Author(s)
  Yasuda H, Higashio K, Suda T
- Journal Title
  
  Vitamin D, Elsevier 2^<nd> Edition
  
  Pages: 665-685
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390465
[Journal Article] Feldman, Vitamin D and osteoclastogenesis2005
- Author(s)
  Hisataka Yasuda, Kanji Higashio, Tatsuo Suda
- Journal Title
  
  In Vitamin D, 2^<nd> edition (ed. D. W. Pike, and F. Glorieux) (Elsevier)
  
  Pages: 665-685
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390465
[Journal Article] Recent advance in basic research for osteoporosis2004
- Author(s)
  Tatsuo Suda, Chisato Miyaura
- Journal Title
  
  Nippon Rinsho 62 (supplement 2)
  
  Pages: 13-20
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390465
[Journal Article] Vitamin D and bone -How does vitamin D regulate bone formation and resorption?-2004
- Author(s)
  Suda T
- Journal Title
  
  Proceedings of The Japan Academy, Ser.B 80(9)
  
  Pages: 407-421
- Data Source
  KAKENHI-PROJECT-15390465
[Journal Article] Vitamin D and bone2004
- Author(s)
  Tatsuo Suda
- Journal Title
  
  Osteoporosis Japan 12
  
  Pages: 356-357
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390465
[Journal Article] ビタミンDと骨2004
- Author(s)
  須田立雄
- Journal Title
  
  Osteoporosis Japan 12(2)
  
  Pages: 356-357
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390465
[Journal Article] Vitamin D and bone -How does vitamin D regulate bone formation and resorption?-2004
- Author(s)
  Tatsuo Suda
- Journal Title
  
  Proceedings of The Japan Academy, Ser. B 80
  
  Pages: 407-421
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390465
[Journal Article] Vitamin D and bone -How does vitamin D regulate bone formation and resorption?-2004
- Author(s)
  Suda T
- Journal Title
  
  Proceedings of the Japan Academy, Ser.B 80(9)
  
  Pages: 407-421
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390465
[Journal Article] The origin and evolution of bone tissue -prologue-2004
- Author(s)
  Tatsuo Suda
- Journal Title
  
  The Bone 18
  
  Pages: 421-426
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390465
[Journal Article] 骨粗鬆症の成因研究の現状2004
- Author(s)
  須田立雄, 宮浦千里
- Journal Title
  
  日本臨床 62(2)
  
  Pages: 13-20
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390465
[Journal Article] 硬組織の起源と進化序説2004
- Author(s)
  須田立雄
- Journal Title
  
  The Bone 18(4)
  
  Pages: 421-426
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390465
[Patent] 動脈硬化の治療剤2005
- Inventor(s)
  須田立雄, 片桐岳信, 東尾侃二, 後藤雅昭, 小平邦彦
- Industrial Property Rights Holder
  埼玉医学大学, 中外製薬
- Industrial Property Number
  2005-198977
- Filing Date
  2005-07-07
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390533
[Patent] 動脈硬化の治療剤2005
- Inventor(s)
  須田立雄、片桐岳信、東尾侃二、後藤雅昭、小平邦彦
- Industrial Property Rights Holder
  埼玉医科大学、中外製薬
- Industrial Property Number
  2005-198977
- Filing Date
  2005-07-07
- Data Source
  KAKENHI-PROJECT-16390533
[Presentation] DNAのメチル化を介した骨芽細胞分化のエピジェネティクス制御2015
- Author(s)
  大久保正彦, 松本征仁, 榎木祐一郎, 佐藤毅, 須田立雄, 岡﨑康司, 依田哲也
- Organizer
  第33回日本骨代謝学会
- Place of Presentation
  京王プラザホテル(東京都新宿区)
- Year and Date
  2015-07-22
- Data Source
  KAKENHI-PROJECT-25462380
[Presentation] 新たな破骨細胞分化抑制因子としてのPax6の機能解析2015
- Author(s)
  大久保正彦, 松本征仁, 甲川昌和, 八塚由紀子, 榎木祐一郎, 佐藤毅, 片山茂裕, 須田立雄, 岡﨑康司, 依田哲也
- Organizer
  第69回日本口腔科学会学術集会
- Place of Presentation
  大阪国際会議場(大阪府大阪市)
- Year and Date
  2015-05-13
- Data Source
  KAKENHI-PROJECT-25462380
[Presentation] Self-limiting system of osteoclast differentiation by the Paired-box Domain Transcription factor Pax62013
- Author(s)
  Masahito Matsumoto, Masakazu Kogawa, Koji Hisatake, Gerald J. Atkins, David M. Findlay, Yuichiro Enoki, Tsuyoshi Sato, Peter C. Gray8, Yukiko Kanesaki-Yatsuka5, Paul H. Anderson9, Seiki Wada2, Naoki Kato4, Aya Fukuda1,7, Shigehiro Katayama, Masafumi Tsujimoto, Tetsuya Yoda, Tatsuo Suda, Yasushi Okazaki
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25462380
[Presentation] Dual functional roles of Pax6 in the regulation of bone and glucose metabolism Osteoclast Differentiation.2013
- Author(s)
  Kogawa, M., Hisatake, K., Atkins, G.J., Findlay, D.M., Enoki, Y., Sato, Tsuyoshi, Gray, P, Wada, S., Kato, N., Fukuda, A., Katayama, S., Tsujimoto, M., Yoda, T., Suda, T., Okazaki, Y., and Matsumoto, M.
- Organizer
  ASBMR
- Place of Presentation
  Maryland USA
- Data Source
  KAKENHI-PROJECT-25462380

1. TAKAHASHI Naoyuki (90119222)

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2. MIYAURA Chisato (20138382)

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3. SHINKI Toshimasa (90138420)

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6. ABE Etsuko (70119147)

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7. TAKITO Jiro (00197237)

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28. SHIMA Nobuyuki (30337604)

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37. MATSUMOTO Akira (40064365)

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SUDA TATSUO 須田 立雄

須田 立雄 スダ タツオ

SUDA Tatsuo 須田 立雄

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A study of cross-talk between the expression mechanisms of osteoclast differentiation factor (ODF) and osteoclastogenesis inhibitory factor (OCIF)Principal Investigator

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The roles of nuclear transcription factors in calcium homeostasisPrincipal Investigator

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ヒトPTH受容体遺伝子の導入によるヒト破骨細胞形成系の確立Principal Investigator

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Pathogenesis of bone loss due to estrogen deficiency : Relationship between increased B-lymphopoiesis and bone resorption.Principal Investigator

SUDA TATSUO 須田立雄

須田立雄スダタツオ

SUDA Tatsuo 須田立雄