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SEMBA Kentaro  仙波 憲太郎

… Alternative Names

仙波 憲太郎  センバ ケンタロウ

Less
Researcher Number 70206663
Other IDs
  • ORCIDhttps://orcid.org/0000-0001-7507-8214
Affiliation (Current) 2022: 早稲田大学, 理工学術院, 教授
Affiliation (based on the past Project Information) *help 2021: 早稲田大学, 理工学術院, 教授
2011 – 2017: 早稲田大学, 理工学術院, 教授
2007: Waseda University, Dept. of Life Science and Medical Bioscience, professor
2006: 東京大学, 医科学研究所, 助教授
1999 – 2004: 東京大学, 医科学研究所, 助教授 … More
1995 – 1996: 東京大学, 医科学研究所, 助教授
1991: 東京大学医科学研究所, 制癌研究部, 助手
1989 – 1991: 東京大学, 医科学研究所, 助手 Less
Review Section/Research Field
Principal Investigator
General anatomy (including histology/embryology) / Human pathology / Medical genome science / Obstetrics and gynecology / Medium-sized Section 50:Oncology and related fields
Except Principal Investigator
Biological Sciences / Immunology
Keywords
Principal Investigator
WT1 / SRY / がん / 遺伝子増幅 / ゲノム / 幹細胞 / 細胞分化 / 組織形成 / 乳腺 / 脱分化 … More / 性 / sex / ErbB2 / 発生 / 腎臓 / カエル / 疾患関連遺伝子 / 分子腫瘍学 / ゲノム発現 / 婦人科腫瘍学 / 再生医療 / 乳腺幹細胞 / 性決定 / 生殖腺 / 性逆転 / 精巣 / マイクロアレイ / DNAチップ / microarray / DNA chip / 癌 / プロテオーム / シグナル伝達 / Cancer / gene amplification / proteome / signal transduction / ダイレクトリプログラミング / 癌幹細胞 / リプログラミング / 遺伝子スクリーニング / トラップ法 / 乳腺組織 / ケミカルスクリーニング / 発がん … More
Except Principal Investigator
シグナル伝達 / fyn / Tリンパ球 / 転写制御 / チロシンキナ-ゼ / 癌 / チロシン燐酸化酵素 / lpr / 遺伝子導入 / がん遺伝子 / 遺伝子発現 / 転写因子 / 細胞増殖 / WT1 / 細胞周期 / srcファミリー / yes / lyn / fgr / erbB-2 / ear-1 / ear-3 / サイトカイン / 増殖・分化因子 / 受容体 / 情報伝達 / Srcファミリ- / T細胞抗原レセプタ- / がん原遺伝子 / 抗原受容体 / T細胞活性化反応 / cーyesプロモ-タ- / cーerbBー2 / 癌遺伝子 / リン酸化 / 蛋白質リン酸化酵素 / 癌抑制遺伝子 / リンパ球活性化 / 乳癌 / 増殖因子 / 転写調節 / トランスジェニックマウス / 抗原レセプター / Fyn / T細胞ハイブリドーマ / MRL / lprマウス / チロシン燐酸化 / GAP / PLCγ / 抗原レセプタ- / 活性化 / 細胞内情報伝達 / チロシナ燐酸化 / 遺伝子操作 / 再構成実験系 / NFκB / TRAF6 / HTLV-1 / Tax / DRG / 発現制御 / 骨形成 / 免疫 / 発生 / 器官形成 / 発生・分化 / 免疫学 / NFkB / AP-1 / IKK / 無汗性外胚葉形成不全症 / TRAFタンパク質 / Gタンパク質 / PEBP2 / AML1 / 白血病 / キメラ遺伝子 / RunX / マイクロアレイ / 細胞骨格 / PEBP2β / フィラミン / BAL1 / 国際学術 / 海外派遣 / 細胞社会学 / 薬品設計 / 遺伝子治療 / ウイルス発癌 / 細胞接着 / 癌治療 / 化学発癌 / 情報交換 / ドラッグデザイン / 癌遺伝子治療 / 癌化学療法 / International Scientific Research / Cancer / Information Exchange / Signal Transduction / Cell Cycle / Cell Adhesion / Drug Design / Gene Therapy Less
  • Research Projects

    (19 results)
  • Research Products

    (11 results)
  • Co-Researchers

    (70 People)
  •  正常―がん細胞間作用に基づくがん防御機構の化学生物学的解析Principal Investigator

    • Principal Investigator
      仙波 憲太郎
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 50:Oncology and related fields
    • Research Institution
      Waseda University
  •  Screening for genes involved in efficient reprogramming directly into mammary stem cellsPrincipal Investigator

    • Principal Investigator
      Semba Kentaro
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      General anatomy (including histology/embryology)
    • Research Institution
      Waseda University
  •  Generation of mammary stem cells by direct reprogrammingPrincipal Investigator

    • Principal Investigator
      SEMBA Kentaro
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      General anatomy (including histology/embryology)
    • Research Institution
      Waseda University
  •  Development of experimental techniques for the analysis of amplicomicsPrincipal Investigator

    • Principal Investigator
      SEMBA Kentaro
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Medical genome science
    • Research Institution
      Waseda University
  •  Identification and functional analysis of novel oncogenes involved in the breast cancer genesis and promotionPrincipal Investigator

    • Principal Investigator
      SEMBA Kentaro
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Waseda University
      The University of Tokyo
  •  白血病細胞における細胞骨格・転写・細胞周期の制御異常

    • Principal Investigator
      佐竹 正延
    • Project Period (FY)
      2001 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  Molecular mechanism of sex determination and its diseasePrincipal Investigator

    • Principal Investigator
      SEMBA Kentaro
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      The University of Tokyo
  •  転写制御の異常と細胞の増殖・分化

    • Principal Investigator
      INOUE Jun-ichiro
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
      Keio University
  •  Molecular mechanism of sex determination and its diseasePrincipal Investigator

    • Principal Investigator
      SEMBA Kentaro
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      The University of Tokyo
  •  小児腎腫瘍の発症メカニズムの解析Principal Investigator

    • Principal Investigator
      仙波 憲太郎
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  Information Exchange on Cancer Research with North American

    • Principal Investigator
      YAMAMOTO Tadashi
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      The University of Tokyo
  •  細胞癌化における蛋白質リン酸化

    • Principal Investigator
      秋山 徹
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Osaka University
  •  Tリンパ球抗原レセプターに会合するチロシン燐酸化酵素Fynの機能

    • Principal Investigator
      片桐 拓也
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Immunology
    • Research Institution
      The University of Tokyo
  •  がんの増殖と分化に関連する遺伝子の発現制御

    • Principal Investigator
      長田 重一
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Osaka Bioscience Institute
  •  Srcファミリ-遺伝子fynのリンホ-マ並びに正常リンパ球における発現と機能

    • Principal Investigator
      片桐 拓也
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  がん遺伝子の機能解析

    • Principal Investigator
      山本 雅
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  がん遺伝子の機能解析

    • Principal Investigator
      山本 雅
    • Project Period (FY)
      1990 – 1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  srcファミリー遺伝子fynのリンホーマ並びに正常リンパ球における発現と機能

    • Principal Investigator
      片桐 拓也
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  がん遺伝子の検出と機能解析

    • Principal Investigator
      豊島 久真男
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo

All 2013 2012 2011 2008 2007 2006 Other

All Journal Article Presentation

  • [Journal Article] Gene amplification: mechanisms and involvement in cancer2013

    • Author(s)
      Semba, K et al.
    • Journal Title

      Biomolecular Concepts

      Volume: 4 Pages: 567-582

    • DOI

      10.1515/bmc-2013-0026

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23241064
  • [Journal Article] Gene amplification : mechanisms and involvement in cancer2013

    • Author(s)
      Matsui, A., Ihara, T., Suda, H., Mikami, H., and Semba, K
    • Journal Title

      Biomolecular Concepts

      Volume: 4 Pages: 567-582

    • Data Source
      KAKENHI-PROJECT-23241064
  • [Journal Article] Expression screening of 17q12-21 amplicon reveals GRB7 as an ERBB2-dependent oncogene2012

    • Author(s)
      Saito, M., Kato, Y., Ito, E., Fujimoto, J., Ishikawa, K., Doi, A., Kumazawa, K., Matsui, A., Takebe, S., Ishida, T., Azuma, S., Mochizuki, H., Kawamura, Y., Yanagisawa, Y., Honma, R., Imai, J., Ohbayashi, H., Goshima, N., Semba, K., and Watanabe, S
    • Journal Title

      FEBS letters

      Volume: 586 Pages: 1708-1714

    • Data Source
      KAKENHI-PROJECT-23241064
  • [Journal Article] ErbB2/HER2 : Its Contribution to Basic Cancer Biology and the Development of Molecular Targeted Therapy, Breast Cancer - Carcinogenesis2011

    • Author(s)
      Yamamoto, T., Saito, M., Kumazawa, K., Doi, A., Matsui, A., Takebe, S., Amari, T., Oyama, M., and Semba, K
    • Journal Title

      Cell Growth and Signalling Pathways, Prof. Mehmet Gunduz (Ed.) (InTech)

    • DOI

      10.5772/21965

    • Data Source
      KAKENHI-PROJECT-23241064
  • [Journal Article] FoxA1 as a lineage-specific oncogene in luminal type breast cancer.2008

    • Author(s)
      Yamaguchi, N., Ito, E., Azuma, S., Honma, R., Yanagisawa, Y., Nishikawa, A., Kawamura, M., Imai, J., Tatsuta, K., Inoue, J., Semba, K., Watanabe, S.
    • Journal Title

      Biochem Biophys Res Commun 365

      Pages: 711-717

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591825
  • [Journal Article] NOTCH3 signaling pathway plays crucial roles in the proliferation of ErbB2-negative human breast cancer cells.2008

    • Author(s)
      Yamaguchi, N., Oyama, T., Ito, E., Satoh, H., Azuma, S., Hayashi, M., Shimizu, K., Honma, R., Yanagisawa, Y., Nishikawa, A., Kawamura, M., Imai, J., Ohwada, S., Tatsuta, K., Inoue, J., Semba, K., Watanabe, S.
    • Journal Title

      Cancer Res 68

      Pages: 1881-1888

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591825
  • [Journal Article] AYUMS : an algorithm for completely automatic quantitation based on LC-MS/MS proteome data and its application to the analysis of signal transduction.2007

    • Author(s)
      Saito A, Nagasaki M, Oyama M, Kozuka-Hata H, Semba K, Sugano S, Yamamoto T, Miyano S
    • Journal Title

      BMC Bioinformatics 8

      Pages: 15-15

    • Data Source
      KAKENHI-PROJECT-18591825
  • [Journal Article] Novel clusters of highly expressed genes accompany genomic amplification in breast cancers.2007

    • Author(s)
      Ito, E., Honma, R., Yanagisawa, Y., Imai, J., Azuma, S., Oyama, T., Ohwada, S., Akiyama, T., Nomura, N., Inoue, J., Watanabe, S., Semba, K.
    • Journal Title

      FEBS Lett 581

      Pages: 3909-3914

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591825
  • [Journal Article] Diversity of translation start sites may define increased complexity of the human short ORFeome.

    • Author(s)
      Oyama M, Kozuka-Hata H, Suzuki Y, Semba K, Yamamoto T, Sugano S.
    • Journal Title

      Mol. Cell. Proteomics (in press)

    • Data Source
      KAKENHI-PROJECT-18591825
  • [Presentation] Identification of novel gene amplification units in breast cancer2006

    • Author(s)
      Semba K
    • Organizer
      65^<th> Annual Meeting of the Japanese Cancer Association
    • Place of Presentation
      Yokohama
    • Year and Date
      2006-09-29
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591825
  • [Presentation] 乳癌における新規遺伝子増幅部位の同定2006

    • Author(s)
      仙波憲太郎
    • Organizer
      第65回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2006-09-29
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591825
  • 1.  YAMAMOTO Tadashi (40134621)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 2.  片桐 拓也 (70126100)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  豊島 久真男 (90029760)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  INOUE Jun-ichiro (70176428)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  WATANABE Shinya (70251444)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 6.  須田 容子 (90201582)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  狩野 恭一 (80152825)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  畠山 昌則 (40189551)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  秋山 徹 (70150745)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  佐竹 正延 (50178688)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  ITO Emi (50540796)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 12.  IMAI Junichi (70376739)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 13.  WAGURI Satoshi (30244908)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  ISOGAI Takao (70456185)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  GOSHIMA Naoki (70215482)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 16.  WATANABE Toshiki (30182934)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  YOSHIDA Mitsuaki (80012607)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  HIRAI Hisamaru (90181130)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  HONMA Yoshimi (60192324)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  NAKACHI Kei (00142117)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  NAGAFUCHI Akira (80218023)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  TSUCHIYA Nagahisa (00072314)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  TANAKA Nobuyuki (80222115)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  TACHIMATSU Masae (70117836)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  TAKATA Kenzo (30133721)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  SHIBUYA Hitoshi (10014292)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  SAITOH Izumi (70158913)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  UCHIYAMA Takashi (80151900)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  IMAI Kohzo (60117603)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  ITOH Akira (70012771)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  長田 重一 (70114428)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  藤沢 淳子 (60209038)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  服部 豊 (20189575)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  審良 静男 (50192919)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  西田 栄介 (60143369)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  月田 早智子 (00188517)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  岡田 雅人 (10177058)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  小安 重夫 (90153684)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 39.  鈴木 元 (00179201)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 40.  大海 忍 (20160046)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 41.  豊田 裕 (90050418)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 42.  秋山 泰身 (50327665)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 43.  正井 久雄 (40229349)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 44.  村上 洋太 (20260622)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 45.  西村 善文 (70107390)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 46.  永田 宏次 (30280788)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 47.  中畑 龍俊 (20110744)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 48.  千田 和広 (00192188)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 49.  永井 義之 (20022874)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 50.  森本 幾夫 (30119028)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 51.  達家 雅明 (50216991)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 52.  菅村 和夫 (20117360)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 53.  渋谷 正史 (10107427)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 54.  佐々木 卓也 (40241278)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 55.  川畑 正博 (60224838)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 56.  垣塚 彰 (80204329)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 57.  石崎 寛治 (70111987)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 58.  矢守 隆夫 (60200854)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 59.  吉田 純 (40158449)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 60.  浜田 洋文 (00189614)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
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  • 63.  月田 承一郎 (50155347)
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  • 70.  松田 覚
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