Morimoto Chikao 森本幾夫

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MORIMOTO Chikao 森本幾夫

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Researcher Number	30119028
Other IDs
Affiliation (Current)	2023: 順天堂大学, 大学院医学研究科, 特任教授
Affiliation (based on the past Project Information) *help	2021 – 2023: 順天堂大学, 大学院医学研究科, 特任教授 2017 – 2020: 順天堂大学, 医学(系)研究科(研究院), 特任教授 2015 – 2016: 順天堂大学, 医学(系)研究科(研究院), 客員教授 2014: 順天堂大学, 医学(系)研究科(研究院), 教授 2014: 順天堂大学, 大学院医学研究科, 教授 … More 2013: 順天堂大学, 医学(系)研究科(研究院), その他 2013: 順天堂大学, 医学(系)研究科(研究院), 客員教授 2012: 順天堂大学, 医学(系)研究科(研究院), 教授 2012: 順天堂大学, 大学院・医学研究科, 客員教授 1995 – 2011: 東京大学, 医科学研究所, 教授 2010: 東京大学, 医科学研究所先端医療研究センター免疫病態分野, 教授 1999: 東京大学, 大学院・医科学研究所, 教授 1997: 東京大学, 医科学研究所, 助手 Less
Review Section/Research Field	Principal Investigator 内科学一般 / 膠原病・アレルギー・感染症内科学 / Biological Sciences / Basic Section 49030:Experimental pathology-related / Respiratory organ internal medicine / Collagenous pathology/Allergology / Hematology / Infectious disease medicine / Carcinogenesis Except Principal Investigator 内科学一般 … More / Biological Sciences / Basic Section 52050:Embryonic medicine and pediatrics-related / Pediatrics / Endocrinology / 膠原病・アレルギー・感染症内科学 / Immunology / Gastroenterology Less
Keywords	Principal Investigator CD26 / Cas-L / チロシンリン酸化 / β1インテグリン / DPPIV / RANTES / Dipeptidyl peptidase IV / CD28 / CD4メモリーT細胞 / CD9 … More / ヒト化CD26抗体 / 自己免疫疾患 / lck / Fyn / 共刺激 / 癌転移 / T細胞共刺激 / SDF-1α / HIV感染 / 悪性中皮腫 / ERK / 細胞遊走 / Caveolin-1 / CD86 / 共刺激分子 / taxトランスジェニックマウス / 関節リウマチ / シグナル分子 / TGF-β / マンノース6リン酸 / メモリーT細胞 / シグナル伝達 / VLA / CD29 / 炎症性腸疾患 / 慢性炎症 / IL-26 / Tetanus Toxid / CD45RA / T細胞 / T cell costimulation / インスリン成長因子II受容体 / ADA / CD4 memory T cells / CD40 / CD27 / リンパ球遊走 / ADA結合蛋白 / アデノシン / Adenosine deaminase / アポトーシス / USP22 / CD26/DPPIV / GVHD / IL-10 / DPPIV 酵素 / インテグリン / がん幹細胞 / 悪性胸膜中皮腫 / SHP-2 / DPPIV酵素 / CD8T細胞 / 臨床免疫学 / 自己抗原 / IL-2 / SLE / Tax / ドックキング蛋白 / HTLV-1 / ATL / NF-κB / ドッキング蛋白 / internalization / インスリン増殖因子II受容体 / CD45 / IGFIIR / M6P / 癌浸潤 / 核酸 / 移植片対宿主病 / 関節炎 / IL-26中和抗体 / 小児血液学 / 血液免疫学 / 移植免疫学 / 慢性GVHD / BTLA / LAG-3 / 腫瘍免疫 / 免疫制御 / 全身性エリテマトーデス / 免疫チェックポイント分子 / ヒト免疫 / interference RNA / cord T cell / T細胞シグナル / リピッドラフト / アデノシンデアミナーゼ / dipepetidyl peptidase IV / リガンド / 可溶性CD26 / 干渉RNA / 臍帯血T細胞 / autoioimmune diseases / p2l^<ciple> / costimulatory molecule / 共刺激シグナル / ラフト分面 / p21^<cipl> / p21^<cip1> / tyrosine phosphorylation / tax transgenic mice / Rheumatoid Arthritis / signal molecule / β1 integrin / β2GPI / CD45ROメモリー / CD45RAナイーブ / interrnalization / ADA binding protein / BM stromal cells / cyclin-dependent kinase / p27(Kip1) / Extracelluar signal-regulated kinase / integrin α5β1 / B cell progenitors cells / T細胞遊走 / Cas-L分子 / p27^<ldpl> / ストローマル細胞 / p27^<kipl> / Extracellular signal-regulated Kinase(ERK) / β1 / インテグリンα1 / 前駆B細胞 / insulin-like growth factor II receptor / mannose 6-phosphate / adenosine deaminase / dipeptidyl peptidase IV / MIP-1β / T cell migration / DPPIV enzyme / CD4 naive T cells / CD70 / TNF受容体族 / リンパ球遊送 / CD4ナイーブT細胞 / リンパ球遊素 / CD4 メモリーT細胞 / CD4 ナイーブT細胞 / HIV infection / Lymphocyte migration / SDF-1alpha / Chemokine / CDメモリーT細胞 / Adenosine diaminase / SDF-12 / ケモカイン / Dipeptidyl peptidase N / adenosine / Costimulatory molecule / TCR複合体 / CD3 / co-stimulatory分子 / costimylatory分子 / Costimulatory / Dipeptidyl peptidaseIV / ⑦ CD26単クローン抗体 / ⑤ ヒト化CD26抗体 / ④ 重症呼吸器感染症 / ② コロナウイルス / ① MERS感染症 / トランスジェニックマウス / (1) MERS感染症 / エピトープ / CD26単クローン抗体 / 重症呼吸器感染症 / CD26/DPPⅣ / コロナウイルス / MERS感染症 / β1α5 / 脱ユビキチン酵素 / アゴニスト / 細胞増殖 / CD26抗体 / SSTR4 / 浸潤転移 / 脱ユビキチン酵素22（USP22） / ソマトスタチン受容体４（SSTR4） / ペリオスチン / α5β1インテグリン / CD34 / 表面抗原マーカー / エピジェネティック / がん / ヒストン脱ユビキチン酵素 / RNAi / ノックダウン / 癌幹細胞 / CD24 / B-ALL / エピジェネティックス / Fas Ligand / 糖尿病 / Granzyme B / 細胞障害作用 / グランザイムB / サイトカイン産生 / CD28分子 / ヒト免疫系 / CD26分子 / ヒト化 CD26 抗体 / xeno-GVHD / グランザイム B / CD8T 細胞 / EGF / 細胞接着 / 肺がん / EGF-R / p27^<Kipl> / ADCC / 免疫不全マウス / アスベスト / 接着分子 / Smad / Lipid raft / Efs / p130^<Cas> / Nck / IRAK-1 / Tollip / CARMA-1 / 共刺激リガンド / エフェクターT細胞 / TIA-1陽性T細胞 / CD26陽性T細胞 / 異種GVHDマウス / caveolin.1 / Xeno-GVHD / caveolin-1 / リウマチ学 / 膠原病 / Smad7 / Smad6 / ミトコンドリア / Jurkat T cell / B BOX / Ring Finger / TRIM motif / IL-2産生 / T細胞活性化 / p-body / シェーグレン症候群 / Ro52 / 細胞骨格 / 中間フィラメント / ビメンチン / MICAL(a Molecule Interacting Cas-L) / HEF-1 / tax / HTLV-I / T細胞受容体シグナル / クロスリンク / ラフト分画 / インテグリン分子 / 癌増殖 / FAK / CD29インテグリン分子 / pp105 / pp125FAK / 細胞外基質蛋白 / VLAインテグリン … More Except Principal Investigator 分子生物学 / シグナル伝達 / 関節リウマチ / CD26 / 線維化 / GVHD / 造血幹細胞移植 / IL-26 / 慢性GVHD / DRUG DEVELOPMENT / PHARMACOLOGY / MOLECULAR BIOLOGY / TRANSCRIPTION FACTOR / 創薬 / 遺伝子発現 / 転写因子 / PCR / 細胞増殖 / インテグリン / がん / トランスジェニックマウス / HTLV-I / ノックアウトマウス / IL-1レセプターアンタゴニスト / 粘膜免疫 / 臓器線維症 / 肺線維症 / 小児血液学 / 移植免疫学 / DPP4 / caveolin-1 / Caveolin-1 / CANCER / VASCULAR DISEASE / ANGIOGENESIS / 腫瘍学 / 循環器病学 / VEGF / 血管内皮細胞 / 低酸素 / 腫瘍 / STEROID / GENE EXPRESSION / NUCLEAR RECEPTOR / 核内受容体 / ステロイドホルモン / 内分泌学 / 薬理学 / リガンド / レドックス制御 / グルココルチコイド受容体 / 免疫 / 炎症 / グルココルチコイド / 核内レセプター / monoclonal antibody / signal transduction / receptor / cytokine / Immunology / molecular biology / 箪クローン抗体 / レセプター / 単クローン抗体 / 受容体 / サイトカイン / 免疫学 / Gene Therapy / Drug Design / Cell Adhesion / Cell Cycle / Signal Transduction / Information Exchange / Cancer / International Scientific Research / 癌化学療法 / 癌遺伝子治療 / ドラッグデザイン / 情報交換 / 化学発癌 / 癌治療 / 細胞接着 / ウイルス発癌 / 遺伝子治療 / 薬品設計 / 細胞周期 / 細胞社会学 / 癌 / 海外派遣 / 国際学術 / アダプタータンパク質 / マグロライド / アダプター蛋白質 / マクロライド / Nedd9 / Cas-L / ドッキング蛋白質 / 接着分子 / コラーゲン誘導関節炎 / 細胞内寄生菌 / 自然免疫 / オートファジー / クローン病 / マクロファージ / 腸内細菌 / 炎症性腸疾患 / IL-6 / IL-1 / CD82 / MMP-7 / メタロプロテアーゼ / 浸潤転移 / 細胞運動 / 膜型マトリックスメタロプロテアーゼ / ヒアルロン酸 / MTCBP-1 / 細胞外基質 / 癌細胞 / ラミニン / CD44 / MMP-2 / MT1-MMP / マトリックスメタロプロテアーゼ / 浸潤・転移 / 遺伝要因 / 関節炎 / 自己免疫 / HIV感染症 / 慢性関節リウマチ / 細胞表面分子 / ガングリオシド / ヒトT細胞 / 抗原提示細胞 / AIDA / AIDS / EBVトランスフォーメーション / リウマトイド因子 / 抗原特異的T細胞 / HIV感染 / エイズリンパ腫 / インターロイキン8 / インターロイキン2 / 細胞傷害性T細胞 / 免疫不全 / ヒト免疫不全ウイルス / アポトーシス / CXCR-4 / Fas / HHV8 / CTL / CXCR4 / HIV / エイズ Less

Molecular understanding of an innovative therapy for chronic inflammatory diseases targeting human Th17 cytokine IL-26Principal Investigator
- Principal Investigator
  
  森本幾夫
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Juntendo University
ヒト免疫特有の炎症性因子IL-26に基づく慢性炎症病態の解明と新規治療法の開発Principal Investigator
- Principal Investigator
  
  森本幾夫
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Juntendo University
Scientific research on development of anti-fibrotic agent targeting multi-organ profibrotic factor IL-26 in GVHD
- Principal Investigator
  
  Kei Ohnuma
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Juntendo University
Molecular understanding of CD26-mediated immune regulatory mechanism and development of novel molecular targeted therapy for the treatment of refractory autoimmune diseasesPrincipal Investigator
- Principal Investigator
  
  Morimoto Chikao
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Juntendo University
Mechanism of lung fibrosis in chronic GVHD
- Principal Investigator
  
  OHNUMA Kei
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Juntendo University
Role of CD26 molecule in the infection of MERS(Middle East respiratory syndrome) virus and development of new therapyPrincipal Investigator
- Principal Investigator
  
  MORIMOTO CHIKAO
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Infectious disease medicine
- Research Institution
  Juntendo University
Development of new therapeutic modalities for Rheumatoid Arthritis
- Principal Investigator
  
  IWATA SATOSHI
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Juntendo University
  The University of Tokyo
Association of deubiquitin ligase and cell surface molecules regulates the pathophysiology of malignant pleural mesotheliomaPrincipal Investigator
- Principal Investigator
  
  MORIMOTO Chikao
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Juntendo University
Basic research of defining the function of CD26 on human immune system and its clinical application for autoimmune diseases.Principal Investigator
- Principal Investigator
  
  MORIMOTO Chikao
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Juntendo University
  The University of Tokyo
To determine the epigenetic regulatory mechanism of cancer stem cells by cell surface molecules.Principal Investigator
- Principal Investigator
  
  MORIMOTO Chikao
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Carcinogenesis
- Research Institution
  The University of Tokyo
β1インテグリン及びその関連分子の癌転移・浸潤及び癌病態における意義の解析Principal Investigator
- Principal Investigator
  
  森本幾夫
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Elucidation of intestinal mucosal immune system through the intracellular processing mechanisms of bacteria and its application for novel therapy of inflammatory bowel disease
- Principal Investigator
  
  INOUE Nagamu
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research a proposed research project)
- Research Field
  
  Gastroenterology
  Immunology
- Research Institution
  Keio University
悪性中皮腫の発生機構及び病態の解明Principal Investigator
- Principal Investigator
  
  森本幾夫
- Project Period (FY)
  2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  The University of Tokyo
癌浸潤・転移におけるβ1インテグリン及び関連分子の役割の解明と臨床応用の探索Principal Investigator
- Principal Investigator
  
  森本幾夫
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
β1インテグリン及び下流ドッキング蛋白Cas-Lのがん浸潤、転移での役割Principal Investigator
- Principal Investigator
  
  森本幾夫
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Basic Approach for the Development of Molecular Target Therapy for Autoimmune Diseases and Immune-Mediated Disorders.Principal Investigator
- Principal Investigator
  
  MORIMOTO Chikao
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  The University of Tokyo
SSA/Ro52分子の構造と機能解析及びそのSLE等膠原病への治療応用Principal Investigator
- Principal Investigator
  
  森本幾夫
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  The University of Tokyo
Basic study of molecular target therapy for autoimmune diseases and immune deficiency diseases based on CD26Principal Investigator
- Principal Investigator
  
  MORIMOTO Chikao
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  The University of Tokyo
HTLV-1蛋白taxとCas-Lの相互作用の解析とATL・HAAPへの治療応用Principal Investigator
- Principal Investigator
  
  森本幾夫
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  内科学一般
- Research Institution
  The University of Tokyo
関節リウマチの遺伝要因の解明
- Principal Investigator
  
  岩倉洋一郎
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
β1インテグリンとその会合分子(CD9,CD82)の癌増殖、浸潤、転移での役割Principal Investigator
- Principal Investigator
  
  森本幾夫
- Project Period (FY)
  2001 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Analysis of the function of lymphocyte adhesion molecules and its clinical significances in autoimmune diseasesPrincipal Investigator
- Principal Investigator
  
  MORIMOTO Chikao
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  内科学一般
- Research Institution
  The University of Tokyo
The development of specific immune regulatory drugs utilizing the structure and function of CD26Principal Investigator
- Principal Investigator
  
  MORIMOTO Chikao
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  内科学一般
- Research Institution
  The University of Tokyo
関節リウマチの遺伝要因の解明
- Principal Investigator
  
  岩倉洋一郎
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
細胞外基質分解とがん細胞の浸潤制御機構
- Principal Investigator
  
  清木元治
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
CD26分子とHIV tatの相互作用による抗HIV療法の確立Principal Investigator
- Principal Investigator
  
  森本幾夫
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  内科学一般
- Research Institution
  The University of Tokyo
新しいシグナル伝達分子Cas-Lの癌増殖、浸潤、転移における役割Principal Investigator
- Principal Investigator
  
  森本幾夫
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  The University of Tokyo
Analysis of CD29/VLA integrin in T cell immune regulation and its clinical significancePrincipal Investigator
- Principal Investigator
  
  MORIMOTO Chikao
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  内科学一般
- Research Institution
  The University of Tokyo
Molecular mechanism of angiogenesis and clinical application
- Principal Investigator
  
  TANAKA Hirotoshi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  The University of Tokyo
Structure and function of memory T cell marker CD26Principal Investigator
- Principal Investigator
  
  MORIMOTO Chikao
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  内科学一般
- Research Institution
  The University of Tokyo
新しいシグナル伝達分子Cas-Lの癌浸潤、転移における役割Principal Investigator
- Principal Investigator
  
  森本幾夫
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  The University of Tokyo
MOLECULAR MECHANISM OF GLUCOCORTICOID RECEPTOR REGULATION
- Principal Investigator
  
  TANAKA Hirotoshi
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Endocrinology
- Research Institution
  The University of Tokyo
  Asahikawa Medical College
Development of specific imuune regulatoly drugs by the cell surface molecules.Principal Investigator
- Principal Investigator
  
  MORIMOTO Chikao
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  内科学一般
- Research Institution
  The University of Tokyo
ヒトT細胞における6C2分子の機能とその臨床的意義
- Principal Investigator
  
  本間利夫
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  The University of Tokyo
Analysis of CD26 mediated signal transduction mechanism.Principal Investigator
- Principal Investigator
  
  MORIMOTO Chikao
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  Hematology
- Research Institution
  The University of Tokyo
Determination of molecular basis of immunoregulation of human T cell circuit and its clinical significancesPrincipal Investigator
- Principal Investigator
  
  MORIMOTO Chikao
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  内科学一般
- Research Institution
  The University of Tokyo
インテグリン由来シグナル伝達機構の解析Principal Investigator
- Principal Investigator
  
  森本幾夫
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
HIV感染者におけるウイルス抗原特異的T細胞の誘導
- Principal Investigator
  
  HOSONO Osamu
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  The University of Tokyo
Development of immunoregulatory therapy via CD26 activation pathway.Principal Investigator
- Principal Investigator
  
  MORIMOTO Chikao
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  内科学一般
- Research Institution
  The University of Tokyo
Structural and Functional Analysis of Human Interleukin-12 Receptor
- Principal Investigator
  
  KAWASAKI Hiroshi
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  The University of Tokyo
エイズの病態と制御に関する基礎研究柱3.病態の免疫学的基盤
- Principal Investigator
  
  UCHIYAMA Takashi
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
Information Exchange on Cancer Research with North American
- Principal Investigator
  
  YAMAMOTO Tadashi
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  The University of Tokyo

[Book] Regulation of proliferation of malignant mesothelioma cells by CD26-cyclophilin A molecular complex. In: Advanced in Medicine and Biology.2019
- Author(s)
  Okamoto T, Hatano R, Nakano K, Yamada T, Yamazaki H, Kaneko Y, Dang NH, Morimoto C, Ohnuma K.
- Total Pages
  283
- Publisher
  Nova Science Publishers, Inc.
- ISBN
  9781536166903
- Data Source
  KAKENHI-PROJECT-18H02782
[Book] Advances in Medicine and Biology2018
- Author(s)
  Hatano R, Ohnuma K, Yamada T, Okamoto T, Komiya E, Otsuka H, Itoh T, Yamazaki H, Iwao N, Kaneko Y, Dang NH, Morimoto C.
- Total Pages
  45
- Publisher
  Nova Science Publishers, Inc.
- Data Source
  KAKENHI-PROJECT-16H05345
[Book] THE USE OF THE HUMANIZED ANTI-CD26 MONOCLONAL ANTIBODY YS110 AS A NOVEL TARGETED THERAPY FOR REFRACTORY CANCERS AND IMMUNE DISORDERS2018
- Author(s)
  Hating R, Ohnuma K, Yamada T, Okamoto T, Kaneko Y, Dang NH, Morimoto C.
- Total Pages
  272
- Publisher
  Nova Scientific Publishers
- ISBN
  9781536133486
- Data Source
  KAKENHI-PROJECT-18H02782
[Book] Horizons in Cancer Research2017
- Author(s)
  Ohnuma K, Hatano R, Yamazaki H, KanekoY, Dang NH, Morimoto C.
- Total Pages
  212
- Publisher
  Nova Science Publisher
- ISBN
  9781536105124
- Data Source
  KAKENHI-PROJECT-15H04879
[Book] Horizons in Cancer Research2017
- Author(s)
  Ohnuma, K. Hatano, R. Yamazaki, H. Kaneko, Y. Dang, N. H. Morimoto, C.
- Total Pages
  212
- Publisher
  Nova Science Publishers, Inc.
- Data Source
  KAKENHI-PROJECT-15H04879
[Book] Horizons in Cancer Research2017
- Author(s)
  Ohnuma K, Hatano R, Yamazaki H, Kaneko Y, Dang NH, Morimoto C.
- Total Pages
  33
- Publisher
  Nova Science Publishers, Inc.
- Data Source
  KAKENHI-PROJECT-16H05345
[Book] A New Horizon in Malignant Pleural Mesothelioma Management, Horizons in Cancer Researc2016
- Author(s)
  Ohnuma K, Hatano R, Yamazaki H, KanekoY, Dang NH, Morimoto C1.Ohnuma K, Hatano R, Yamazaki H, KanekoY, Dang NH, Morimoto C
- Total Pages
  220
- Publisher
  Nova Science Publishers,Inc
- Data Source
  KAKENHI-PROJECT-16H05345
[Book] Adv Clin Chem2011
- Author(s)
  Ohnuma K, Hosono O, Dang NH, Morimoto C
- Publisher
  Dipeptidyl peptidase in autoimmune pathophysiology
- Data Source
  KAKENHI-PROJECT-22650223
[Book] Dipeptidyl peptidase in autoimmune pathophysiology2011
- Author(s)
  Ohnuma K, Hosono O, Dang NH, Morimoto C
- Publisher
  Adv Clin Chem
- Data Source
  KAKENHI-PROJECT-22390200
[Book] Advances in Clinical Chemistory2011
- Author(s)
  Ohnuma K, Hosono O, Dang NH, Morimoto C
- Publisher
  Dipeptidyl peptidase in autoimmune pathophysiology
- Data Source
  KAKENHI-PROJECT-22650223
[Book] Advances in Clinical Chemistory2011
- Author(s)
  Ohnuma K, Hosono O, Dang NH, Morimoto C
- Publisher
  Dipeptidyl peptidase in autoimmune pathophysiology
- Data Source
  KAKENHI-PROJECT-22390200
[Book] T-Cell Malignancies : Recent Developmentsand Novel Therapeutic Approaches.2010
- Author(s)
  Yamazaki H, Morimoto C.
- Publisher
  Research Signpost
- Data Source
  KAKENHI-PROJECT-22650223
[Book] The role af CD26 in T-cell biology and T-cell malignancies. T-Cell Malignancies : Recent Developments and Novel Therapeutic Approaches.2010
- Author(s)
  Havre PA, Dang LH, Abe M, Urasaki Y, Ohnuma K, Morimoto C, Dang NH.
- Publisher
  Research Signpost
- Data Source
  KAKENHI-PROJECT-22650223
[Book] Stem cell property for T-cell malignancy. T-Cell Malignancies: Recent Developments and Novel Therapeutic Approaches2010
- Author(s)
  Yamazaki H and Morimoto C
- Publisher
  Edited by Dang NH
- Data Source
  KAKENHI-PROJECT-22390200
[Book] Stem cell property for T-cell malignancy. T-Cell Malignancies : Recent Developments and Novel Therapeutic Approaches2010
- Author(s)
  Yamazaki H and Morimoto C
- Publisher
  Edited by Dang NH
- Data Source
  KAKENHI-PROJECT-22650223
[Book] The role of CD26 in T-cell biology and T-cell malignancies. T-Cell Malignancies: Recent Developments and Novel Therapeutic Approaches2010
- Author(s)
  Havre PA, Dang LH, Abe M, Urasaki Y, Ohnuma K, Morimoto C, Dang NH
- Publisher
  Edited by Dang NH
- Data Source
  KAKENHI-PROJECT-22390200
[Book] The role of CD26 in T-cell biology and T-cell malignancies. T-Cell Malignancies : Recent Developments and Novel Therapeutic Approaches.2010
- Author(s)
  Havre PA, Dang LH, Abe M, Urasaki Y, Ohnuma K, Morimoto C, Dang NH.
- Publisher
  Research Signpost
- Data Source
  KAKENHI-PROJECT-22390200
[Book] T-Cell Malignancies : Recent Developments and Novel Therapeutic Approaches.2010
- Author(s)
  Yamazaki H, Morimoto C.
- Publisher
  Research Signpost
- Data Source
  KAKENHI-PROJECT-22390200
[Book] The role of CD26 in T-cell biology and T-cell malignancies. T-Cell Malignancies : Recent Developments and Novel Therapeutic Approaches
- Author(s)
  Havre PA, Dang LH, Abe M, Urasaki Y, Ohnuma K, Morimoto C, Dang NH
- Publisher
  Edited by Dang NH
- Data Source
  KAKENHI-PROJECT-22650223
[Journal Article] Peripheral endomorphins drive mechanical alloknesis under the enzymatic control of CD26/DPPIV2022
- Author(s)
  Komiya Eriko、Tominaga Mitsutoshi、Hatano Ryo、Kamikubo Yuji、Toyama Sumika、Sakairi Hakushun、Honda Kotaro、Itoh Takumi、Kamata Yayoi、Tsurumachi Munehiro、Kishi Ryoma、Ohnuma Kei、Sakurai Takashi、Morimoto Chikao、Takamori Kenji
- Journal Title
  
  Journal of Allergy and Clinical Immunology
  
  Volume: 149 Issue: 3 Pages: 1085-1096
- DOI
  10.1016/j.jaci.2021.08.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03471, KAKENHI-PROJECT-19K08756, KAKENHI-PROJECT-20K07683, KAKENHI-PROJECT-20K07765, KAKENHI-PROJECT-20K08680, KAKENHI-PROJECT-21K16307, KAKENHI-PROJECT-20K22745
[Journal Article] CD26/Dipeptidyl Peptidase IV and Its Multiple Biological Functions2021
- Author(s)
  Pan Kelsey、Ohnuma Kei、Morimoto Chikao、Dang Nam H
- Journal Title
  
  Cureus
  
  Volume: 13
- DOI
  10.7759/cureus.13495
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02782, KAKENHI-PROJECT-20H03471
[Journal Article] IL-26 mediates epidermal growth factor receptor-tyrosine kinase inhibitor resistance through endoplasmic reticulum stress signaling pathway in triple-negative breast cancer cells2021
- Author(s)
  Itoh Takumi、Hatano Ryo、Horimoto Yoshiya、Yamada Taketo、Song Dan、Otsuka Haruna、Shirakawa Yuki、Mastuoka Shuji、Iwao Noriaki、Aune Thomas M.、Dang Nam H.、Kaneko Yutaro、Okumura Ko、Morimoto Chikao、Ohnuma Kei
- Journal Title
  
  Cell Death and Disease
  
  Volume: 12 Issue: 6 Pages: 520-520
- DOI
  10.1038/s41419-021-03787-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03519, KAKENHI-PROJECT-20H03471, KAKENHI-PROJECT-20K07683, KAKENHI-PROJECT-21K16389
[Journal Article] Serum soluble CD26/DPP4 titer variation is a potential prognostic biomarker in cancer therapy with a humanized anti-CD26 antibody.2021
- Author(s)
  Kaneko Y, Hatano R, Hirota N, Isambert N, Trillet-Lenoir V, You B, Alexandre J, Zalcman G, Valleix F, Podoll T, Umezawa Y, Takao S, Iwata S, Hosono O, Taguchi T, Yamada T, Dang NH, Ohnuma K, Angevin E, Morimoto C.
- Journal Title
  
  Biomark Res
  
  Volume: 9 Issue: 1 Pages: 21-21
- DOI
  10.1186/s40364-021-00273-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07683, KAKENHI-PROJECT-18H02782, KAKENHI-PROJECT-19H03519, KAKENHI-PROJECT-20H03471, KAKENHI-PROJECT-19K22542
[Journal Article] Effector memory CD4+T cells in mesenteric lymph nodes mediate bone loss in food-allergic enteropathy model mice, creating IL-4 dominance2021
- Author(s)
  Ono-Ohmachi Aiko、Udagawa Nobuyuki、Nakamichi Yuko、Koide Masanori、Nakajima-Adachi Haruyo
- Journal Title
  
  Mucosal Immunology
  
  Volume: 14 Issue: 6 Pages: 1335-1346
- DOI
  10.1038/s41385-021-00434-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22729, KAKENHI-PROJECT-20H03176, KAKENHI-PROJECT-20H03471, KAKENHI-PROJECT-20H03872, KAKENHI-PROJECT-21H02394, KAKENHI-PROJECT-21H03125, KAKENHI-PROJECT-19K22728, KAKENHI-PROJECT-20K21689, KAKENHI-PROJECT-21K16389, KAKENHI-PROJECT-19KK0234
[Journal Article] Single-cell atlas of colonic CD8+ T-cells in ulcerative colitis.2020
- Author(s)
  Corridoni D, Antanaviciute A, Gupta T, Fawkner-Corbett D, Aulicino A, Jagielowicz M, Parikh K, Repapi E, Taylor S, Ishikawa D, Hatano R, Yamada T, Xin W, Slawinki H, Bowden R, Napolitani G, Brain O, Morimoto C, Koohy H, Simmons A.
- Journal Title
  
  Nat Med
  
  Volume: 26 Issue: 9 Pages: 1480-1490
- DOI
  10.1038/s41591-020-1003-4
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07683, KAKENHI-PROJECT-19H03519, KAKENHI-PROJECT-20H03471, KAKENHI-PROJECT-19K22542
[Journal Article] Rheumatic diseases associated with immune checkpoint inhibitors in cancer immunotherapy.2019
- Author(s)
  Ohnuma K, Hatano R, Dang NH, Morimoto C.
- Journal Title
  
  Modern Rheumatology
  
  Volume: 29 Pages: 721-732
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02782
[Journal Article] Biological effects of IL-26 on T cell-mediated skin inflammation, including psoriasis.2019
- Author(s)
  Itoh T, Hatano R, Komiya E, Otsuka H, Narita Y, Aune TM, Dang NH, Matsuoka S, Naito H, Tominaga M, Takamori K, Morimoto C, Ohnuma K.
- Journal Title
  
  J Invest Dermatol
  
  Volume: 139 Issue: 4 Pages: 878-889
- DOI
  10.1016/j.jid.2018.09.037
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10008, KAKENHI-PROJECT-17K16353, KAKENHI-PROJECT-16H05345, KAKENHI-PROJECT-19K21278, KAKENHI-PROJECT-18H02782, KAKENHI-PROJECT-18K07396
[Journal Article] Characterization of novel anti-IL-26 neutralizing monoclonal antibodies for the treatment of inflammatory diseases including psoriasis.2019
- Author(s)
  Hatano R, Itoh T, Otsuka H, Okamoto S, Komiya E, Iwata S, Aune TM, Dang NH, Kuwahara-Arai K, Ohnuma K, Morimoto C.
- Journal Title
  
  MAbs
  
  Volume: 11 Pages: 1428-1442
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02782
[Journal Article] Rheumatic diseases associated with immune checkpoint inhibitors in cancer immunotherapy.2019
- Author(s)
  Ohnuma K, Hatano R, Dang NH, Morimoto C.
- Journal Title
  
  Mod Rheumatol
  
  Volume: 印刷中 Issue: 5 Pages: 721-732
- DOI
  10.1080/14397595.2018.1532559
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10008, KAKENHI-PROJECT-16H05345
[Journal Article] Development of novel monoclonal antibodies with specific binding affinity for denatured human CD26 in formalin-fixed paraffin-embedded and decalcified specimens2019
- Author(s)
  Hatano R, Yamada T, Madokoro H, Otsuka H, Komiya E, Itoh T, Narita Y, Iwata S, Yamazaki H, Matsuoka S, Dang NH, Morimoto C
- Journal Title
  
  PLoS ONE
  
  Volume: 14 Issue: 6 Pages: e0218330-e0218330
- DOI
  10.1371/journal.pone.0218330
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22542, KAKENHI-PROJECT-17K16353, KAKENHI-PROJECT-18H02782, KAKENHI-PROJECT-19H03519, KAKENHI-PROJECT-17K10008, KAKENHI-PROJECT-19K21278
[Journal Article] DPP8 is a novel therapeutic target for multiple myeloma.2019
- Author(s)
  Sato T, Tatekoshi A, Takada K, Iyama S, Kamihara Y, Jawaid P, Rehman MU, Noguchi K, Kondo T, Kajikawa S, Arita K, Wada A, Murakami J, Arai M, Yasuda I, Dang NH, Hatano R, Iwao N, Ohnuma K, Morimoto C.
- Journal Title
  
  Sci Rep
  
  Volume: 9 Issue: 1 Pages: 18094-18094
- DOI
  10.1038/s41598-019-54695-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02782, KAKENHI-PROJECT-17K10008
[Journal Article] Effects of repetitive transcranial magnetic stimulation on ER stress-related genes and glutamate, y-aminobutyric acid and glycine transporter genes in mouse brain.2018
- Author(s)
  Ikeda T, Kobayashi S, Morimoto C
- Journal Title
  
  Biochem Biophys Rep
  
  Volume: 17 Pages: 10-16
- DOI
  10.1016/j.bbrep.2018.10.015
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05345
[Journal Article] A novel role for CD26/dipeptidyl peptidase IV as a therapeutic target in selected immune disorders and cancers2018
- Author(s)
  Ohnuma K, Hatano R, Komiya E, Otsuka H, Itoh T, Iwao N, Kaneko Y, Yamada T, Dang NH, Morimoto C
- Journal Title
  
  Front Biosci
  
  Volume: 印刷中
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05345
[Journal Article] A novel role for CD26/dipeptidyl peptidase IV as a therapeutic target2018
- Author(s)
  Ohnuma K, Hatano R, Komiya E, Otsuka H, Itoh T, Iwao N, Kaneko Y, Yamada T, Dang NH, Morimoto C.
- Journal Title
  
  Front Biosci
  
  Volume: 23 Issue: 9 Pages: 1754-1779
- DOI
  10.2741/4671
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02782
[Journal Article] Targeting CD26 suppresses proliferation of malignant mesothelioma cell via downmodulation of ubiquitin-specific protease 22.2018
- Author(s)
  Okamoto T, Yamazaki H, Hatano R, Yamada T, Kaneko Y, Xu CW, Dang NH, Ohnuma K, Morimoto C.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 504 Issue: 2 Pages: 491-498
- DOI
  10.1016/j.bbrc.2018.08.193
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10008, KAKENHI-PROJECT-16H04714, KAKENHI-PROJECT-16H05345, KAKENHI-PROJECT-18H02782
[Journal Article] CD26 is a potential therapeutic target by humanized monoclonal antibody for the treatment of multiple myeloma2018
- Author(s)
  Hiroko Nishida, Mutsumi Hayashi, Chikao Morimoto, Michiie Sakamoto, Taketo Yamada
- Journal Title
  
  Blood Cancer Journal
  
  Volume: 8(99) Issue: 11 Pages: 1-17
- DOI
  10.1038/s41408-018-0127-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07180, KAKENHI-PROJECT-16H04714, KAKENHI-PROJECT-16H05345
[Journal Article] Gene expression microarray data from mouse CBS treated with rTMS for 30 days, mouse cerebrum and CBS treated with rTMS for 40 days2018
- Author(s)
  Ikeda T, Kobayashi S, Morimoto C.
- Journal Title
  
  Data Brief
  
  Volume: 17 Pages: 1078-1081
- DOI
  10.1016/j.dib.2018.01.079
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05345
[Journal Article] Gene expression microarray data from mouse cerebrum treated with rTMS for 30 days.2017
- Author(s)
  Ikeda T, Kobayashi S, Morimoto C.
- Journal Title
  
  Data Brief.
  
  Volume: 15 Pages: 948-969
- DOI
  10.1016/j.dib.2017.10.034
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05345
[Journal Article] First-in-human phase 1 of YS110, a monoclonal antibody directed against CD26 in advanced CD26-expressing cancers2017
- Author(s)
  Angevin, E. Isambert, N. Trillet-Lenoir, V. You, B. Alexandre, J. Zalcman, G. Vielh, P. Farace, F. Valleix, F. Podoll, T. Kuramochi, Y. Miyashita, I. Hosono, O. Dang, N. H. Ohnuma, K. Yamada, T. Kaneko, Y. Morimoto, C.
- Journal Title
  
  Br J Cancer
  
  Volume: 印刷中 Issue: 9 Pages: 1-9
- DOI
  10.1038/bjc.2017.62
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04879, KAKENHI-PROJECT-16H04714, KAKENHI-PROJECT-15K15324, KAKENHI-PROJECT-16H05345
[Journal Article] Focus on CD26/Dipeptidyl Peptidase IV as a Therapeutic Target.2017
- Author(s)
  Doonan BP, Ohnuma K, Dang LH, Morimoto C, Dang NH.
- Journal Title
  
  Current Cancer Therapy Reviews
  
  Volume: 13 Issue: 2 Pages: 1-13
- DOI
  10.2174/1573394713666170907160734
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04879
[Journal Article] First-in-Human phase 1 of YS110, a monoclonal antibody directed against CD26 in advanced CD26-expressing cancers2017
- Author(s)
  Angevin E, Isambert N, Trillet-Lenoir V, You B, Alexandre J, Zalcman G, Vielh P, Farace F, Valleix F, Podoll T, Kuramochi Y, Miyashita I, Hosono O, Dang NH, Ohnuma K, Yamada T, Kaneko Y, Morimoto C
- Journal Title
  
  Br.J.Cancer
  
  Volume: 62 Pages: 1-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05345
[Journal Article] Current and Emerging Therapy for Malignant Pleural Mesothelioma: Focus on CD26/Dipeptidyl Peptidase IV as a Therapeutic Target.2017
- Author(s)
  Doonan BP, Ohnuma K, Dang LH, Morimoto C, Dang NH.
- Journal Title
  
  Current Cancer Therapy Reviews.
  
  Volume: 13 Pages: 1-13
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05345
[Journal Article] A possible role for CD26/DPPIV enzyme activity in the regulation of psoriatic pruritus2017
- Author(s)
  Komiya, E. Hatano, R. Otsuka, H. Itoh, T. Yamazaki, H. Yamada, T. Dang, N. H. Tominaga, M. Suga, Y. Kimura, U. Takamori, K. Morimoto, C. Ohnuma, K.
- Journal Title
  
  J Dermatol Sci
  
  Volume: 印刷中 Issue: 3 Pages: 212-221
- DOI
  10.1016/j.jdermsci.2017.03.005
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04879, KAKENHI-PROJECT-16H04714, KAKENHI-PROJECT-16H05345, KAKENHI-PROJECT-15K15324, KAKENHI-PROJECT-14J12067, KAKENHI-PROJECT-17K10008, KAKENHI-PROJECT-17K16353, KAKENHI-PROJECT-26830114, KAKENHI-PROJECT-26860760, KAKENHI-PROJECT-15K08680, KAKENHI-PROJECT-16K08997
[Journal Article] Identification of senescent cell surface targetable protein DDP4.2017
- Author(s)
  71.Kim KM, Noh JH, Bodogai M, Martindale JL, Yang X, Indig FE, Basu SK, Ohnuma K, Morimoto C, Johnson PF, Biragyn A, Abdelmohsen K, Gorospe M.
- Journal Title
  
  Genes Dev
  
  Volume: 31 Issue: 15 Pages: 1529-1534
- DOI
  10.1101/gad.302570.117
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04879, KAKENHI-PROJECT-16H05345
[Journal Article] Transforming growth factor-β-induced CUX1 isoforms are associated with fibrosis in systemic sclerosis lung fibroblast2016
- Author(s)
  Ikeda T, Fragiadaki M,Shi-wen Xu, Ponticos M, Khan K, Denton C, Garcia P, Bou-Gharios G, Yamakawa A, Morimoto C, Abraham D
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 7 Pages: 246-252
- DOI
  10.1016/j.bbrep.2016.06.022
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05345
[Journal Article] CD26抗体を基盤とするトランスレーショナルリサーチ：悪性中皮腫の新規治療法開発を目指して2016
- Author(s)
  森本幾夫、大沼圭
- Journal Title
  
  The Japanese Journal of Pediatric Hematology / Oncology
  
  Volume: 53 Issue: 3 Pages: 182-188
- DOI
  10.11412/jspho.53.182
- NAID
  130005606021
- ISSN
  2187-011X, 2189-5384
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05345
[Journal Article] Inhibition of VEGF-dependent angiogenesis by the anti-CD82 monoclonal antibody 4F9 through regulation of lipid raft microdomains2016
- Author(s)
  Nomura, S. Iwata, S. Hatano, R. Komiya, E. Dang, N. H. Iwao, N. Ohnuma, K. Morimoto, C.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 474 Issue: 1 Pages: 111-7
- DOI
  10.1016/j.bbrc.2016.04.081
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04879, KAKENHI-PROJECT-16H05345, KAKENHI-PROJECT-15K15324, KAKENHI-PROJECT-26830114, KAKENHI-PROJECT-26860760, KAKENHI-PROJECT-14J12067
[Journal Article] 標的別分子標的薬６）モノクローナル抗体2016
- Author(s)
  大沼圭、森本幾夫
- Journal Title
  
  腎臓内科
  
  Volume: 4 Pages: 52-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05345
[Journal Article] A humanized anti-CD26 monoclonal antibody inhibits cell growth of malignant mesothelioma via retarded G2/M cell cycle transition.2016
- Author(s)
  Hayashi M, Madokoro H, Yamada K, Nishida H, Morimoto C, Sakamoto M, Yamada T.
- Journal Title
  
  Cancer Cell International
  
  Volume: 30 Issue: 1 Pages: 35-35
- DOI
  10.1186/s12935-016-0310-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04714, KAKENHI-PROJECT-16H05345, KAKENHI-PROJECT-16K07180
[Journal Article] Role of IL-26+CD26+CD4 T Cells in Pulmonary Chronic Graft-Versus-Host Disease and Treatment with Caveolin-1-Ig Fc Conjugate2016
- Author(s)
  Ohnuma, K. Hatano, R. Itoh, T. Iwao, N. Dang, N. H. Morimoto, C.
- Journal Title
  
  Crit Rev Immunol
  
  Volume: 36 Issue: 3 Pages: 239-267
- DOI
  10.1615/critrevimmunol.2016018772
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04879, KAKENHI-PROJECT-16H05345, KAKENHI-PROJECT-15K15324, KAKENHI-PROJECT-26860760, KAKENHI-PROJECT-14J12067
[Journal Article] Translational research based on CD26 molecule2016
- Author(s)
  森本幾夫
- Journal Title
  
  Clinical Rheumatology and Related Research
  
  Volume: 28 Issue: 1 Pages: 91-94
- DOI
  10.14961/cra.28.91
- NAID
  130005154613
- ISSN
  0914-8760, 2189-0595
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05345
[Journal Article] Development of New Therapy for Malignant Mesothelioma Based on CD26 Molecule2016
- Author(s)
  Morimoto, C. Ohnuma, K.
- Journal Title
  
  Gan To Kagaku Ryoho
  
  Volume: 43 Pages: 855-62
- Data Source
  KAKENHI-PROJECT-15H04879
[Journal Article] Identification of Nedd9 as a TGF-β-Smad2/3 Target Gene Involved in RANKL-Induced Osteoclastogenesis by Comprehensive Analysis2016
- Author(s)
  Omata Y, Nakamura S, Koyama T, Yasui T, Hirose J, Izawa N, Matsumoto T, Imai Y, Seo S, Kurokawa M, Tsutsumi S, Kadono Y, Morimoto C, Aburatani H, Miyamoto T, Tanaka S.
- Journal Title
  
  PLoS One.
  
  Volume: 11 Issue: 6 Pages: e0157992-e0157992
- DOI
  10.1371/journal.pone.0157992
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04961, KAKENHI-PROJECT-15H04963, KAKENHI-PROJECT-16H05345, KAKENHI-PROJECT-15K15552
[Journal Article] Establishment of anti-mesothelioma monoclonal antibodies2016
- Author(s)
  Mizutani N, Abe M, Matsuoka S, Kajino K, Wakiya M, Ohtsuji N, Hatano R, Morimoto C, Hino O
- Journal Title
  
  BMC Res Notes
  
  Volume: 9 Issue: 1 Pages: 324-324
- DOI
  10.1186/s13104-016-2128-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05345, KAKENHI-PROJECT-26860760, KAKENHI-PROJECT-14J12067
[Journal Article] DPP4 in anti-tumor immunity: going beyond the enzyme.2015
- Author(s)
  Ohnuma K, Hatano R, Morimoto C.
- Journal Title
  
  Nat Immunol.
  
  Volume: 16 Issue: 8 Pages: 791-2
- DOI
  10.1038/ni.3210
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26860760, KAKENHI-PROJECT-15H04879, KAKENHI-PROJECT-14J12067, KAKENHI-PROJECT-26670486
[Journal Article] Modulation of immunological responses and amelioration of collagen-induced arthritis by the novel roxithromycin derivative 5-I.2015
- Author(s)
  Otsuki N, Iwata S, Yamada T, Hosono O, Dang NH, Hatano R, Ohnuma K, Morimoto C.
- Journal Title
  
  Mod Rheumatol.
  
  Volume: 25 Issue: 4 Pages: 562-70
- DOI
  10.3109/14397595.2014.983262
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860760, KAKENHI-PROJECT-14J12067, KAKENHI-PROJECT-26670486
[Journal Article] Comparison of Two Commercial ELISAs against an In-House ELISA for Measuring Soluble CD26 in Human Serum.2015
- Author(s)
  Ohnuma K, Saito T, Hatano R, Hosono O, Iwata S, Dang NH, Ninomiya H, Morimoto C.
- Journal Title
  
  J Clin Lab Anal.
  
  Volume: Vol 29 Issue: 2 Pages: 106-11
- DOI
  10.1002/jcla.21736
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-14J12067, KAKENHI-PROJECT-21679005, KAKENHI-PROJECT-23591434, KAKENHI-PROJECT-24591442, KAKENHI-PROJECT-24659401, KAKENHI-PROJECT-26670486, KAKENHI-PROJECT-26860760
[Journal Article] CD26-mediated induction ofEGR2 and IL-10 as potential regulatory mechanism for CD26 costimulatory pathway2015
- Author(s)
  Hatano R, Ohnuma K, Otsuka H, Komiya E, Taki I, Iwata S, Dang NH, Okumura K, Morimoto C
- Journal Title
  
  J Immunol
  
  Volume: 16 Pages: 791-792
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670486
[Journal Article] Regulation of pulmonary GVHD by IL-26+CD4 T lymphocytes through CD26/caveolin-1 interaction2015
- Author(s)
  Ohnuma K, Hatano R, Aune TM, Otsuka H, Iwata S, Dang NH, Yamada T, Morimoto C
- Journal Title
  
  J.Immunol
  
  Volume: 194(8) Pages: 3697-712
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26670486
[Journal Article] Regulation of pulmonary GVHD by IL-26+CD4 T lymphocytes through CD26/caveolin-1 interaction2015
- Author(s)
  Ohnuma K, Hatano R, Aune TM, Otsuka H, Iwata S, Dang NH, Yamada T, Morimoto C
- Journal Title
  
  J Immunol.
  
  Volume: 194 Pages: 3697-3712
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670486
[Journal Article] CD26-mediated induction of EGR2 and IL-10 as potential regulatory mechanism for CD26 costimulatory pathway.2015
- Author(s)
  Hatano R, Ohnuma K, Otsuka H, Komiya E, Taki I, Iwata S, Dang NH, Okumura K, Morimoto C.
- Journal Title
  
  J Immunol.
  
  Volume: Vol 194 Issue: 3 Pages: 960-72
- DOI
  10.4049/jimmunol.1402143
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-14J12067, KAKENHI-PROJECT-24591442, KAKENHI-PROJECT-26670486, KAKENHI-PROJECT-26830114, KAKENHI-PROJECT-26860760, KAKENHI-PROJECT-15K15324, KAKENHI-PROJECT-15H04879, KAKENHI-PROJECT-26293087
[Journal Article] The Role of Cas-L/NEDD9 as a Regulator of Collagen-induced Arthritis in a Murine Model2015
- Author(s)
  Tomoki Katayose, Satoshi Iwata, Naoki Oyaizu, Osamu Hosono, Taketo Yamada, Nam H Dang, Ryo Hatano, Hirotoshi Tanaka, Kei Ohnuma, Chikao Morimoto
- Journal Title
  
  Biochem Bilphys Res Commun
  
  Volume: 印刷中 Issue: 4 Pages: 1069-75
- DOI
  10.1016/j.bbrc.2015.03.156
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390236, KAKENHI-PROJECT-24591442, KAKENHI-PROJECT-15K15324, KAKENHI-PROJECT-26860760, KAKENHI-PROJECT-15H04879, KAKENHI-PROJECT-14J12067, KAKENHI-PROJECT-26670486
[Journal Article] Regulation of Pulmonary Graft-versus-Host Disease by IL-26+CD26+CD4 T Lymphocytes.2015
- Author(s)
  Ohnuma K, Hatano R, Aune TM, Otsuka H, Iwata S, Dang NH, Yamada T, Morimoto C.
- Journal Title
  
  J Immunol
  
  Volume: 194(8) Issue: 8 Pages: 3697-712
- DOI
  10.4049/jimmunol.1402785
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24591442, KAKENHI-PROJECT-15K15324, KAKENHI-PROJECT-26860760, KAKENHI-PROJECT-15H04879, KAKENHI-PROJECT-14J12067
[Journal Article] Comparison of two commercial ELISAs against an in-house ELISA for measuring soluble CD26 in human serum2015
- Author(s)
  Ohnuma K, Saito T, Hatano R, Hosono O, Iwata S, Dang NH, Ninomiya H, Morimoto C
- Journal Title
  
  J Clin Lab Anal
  
  Volume: Mar29 Pages: 106-111
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670486
[Journal Article] Modulation of immunological responses and amelioration of collagen-induced arthritis by the novel roxithromycin derivative 5-I.2015
- Author(s)
  Otsuki N, Iwata S, Yamada T, Hosono O, Dang NH, Hatano R, Ohnuma K, Morimoto C.
- Journal Title
  
  Mod Rheumatol
  
  Volume: [Epub ahead of print] Pages: 1-9
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24591442
[Journal Article] CD26-mediated regulation of periostin expression contributes to migration and invasion of malignant pleural mesothelioma cells2014
- Author(s)
  Komiya E, Ohnuma K,Yamazaki H, Hatano R, Iwata S, Okamoto T, Dang NH, Yamada T, Morimoto C
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 4 Pages: 609-15
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26670486
[Journal Article] Establishment of monoclonal anti-human CD26 antibodies suitable for immunostaining of formalin- fixed tissue2014
- Author(s)
  Hatano R, Yamada T, Matsuoka S, Iwata S, Yamazaki H, Komiya E, Okamoto T, Dang NH, Ohnuma K, Morimoto C
- Journal Title
  
  Diagn Pathol
  
  Volume: 9 Issue: 1 Pages: 30-30
- DOI
  10.1186/1746-1596-9-30
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21679005, KAKENHI-PROJECT-23390086, KAKENHI-PROJECT-24591442, KAKENHI-PROJECT-24659401, KAKENHI-PROJECT-25670195, KAKENHI-PROJECT-26670486
[Journal Article] CD9 Negatively Regulates CD26 Expression and Inhibits CD26-Mediated Enhancement of Invasive Potential of Malignant Mesothelioma cells2014
- Author(s)
  Okamoto T, Iwata S, Yamazaki H, Hatano R, Komiya E, Dang NH, Ohnuma K, Morimoto C.
- Journal Title
  
  PLoS One
  
  Volume: 9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26670486
[Journal Article] Grassypeptolides as natural inhibitors of dipeptidyl peptidase 8 and T-cell activation.2014
- Author(s)
  Kwan JC, Liu Y, Ratnayake R, Hatano R, Kuribara A, Morimoto C, Ohnuma K, Paul VJ, Ye T, Luesch H.
- Journal Title
  
  Chembiochem.
  
  Volume: Vol 15 Issue: 6 Pages: 799-804
- DOI
  10.1002/cbic.201300762
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-14J12067, KAKENHI-PROJECT-21679005, KAKENHI-PROJECT-24659401, KAKENHI-PROJECT-26670486, KAKENHI-PROJECT-26860760
[Journal Article] Regulation of somatostatin receptor 4-mediated cytostatic effects by CD26 in malignant pleural mesothelioma.2014
- Author(s)
  Yamamoto J, Ohnuma K, Hatano R, Okamoto T, Komiya E, Yamazaki H, Iwata S, Dang NH, Aoe K, Kishimoto T, Yamada T, Morimoto C.
- Journal Title
  
  Br J Cancer.
  
  Volume: Vol 110 Issue: 9 Pages: 2232-45
- DOI
  10.1038/bjc.2014.151
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-14J12067, KAKENHI-PROJECT-21679005, KAKENHI-PROJECT-24591442, KAKENHI-PROJECT-24659401, KAKENHI-PROJECT-26670486, KAKENHI-PROJECT-26860760
[Journal Article] Blockade of CD26 Signaling Inhibits Human Osteoclast Development2014
- Author(s)
  Nishida H1, Suzuki H, Madokoro H, Hayashi M, Morimoto C, Sakamoto M, Yamada T
- Journal Title
  
  J Bone Miner Res
  
  Volume: 29 Pages: 609-15
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26670486
[Journal Article] CD26-mediated regulation of periostin expression contributes to migration and invasion of malignant pleural mesothelioma cells.2014
- Author(s)
  Komiya E, Ohnuma K, Yamazaki H, Hatano R, Iwata S, Okamoto T, Dang NH, Yamada T, Morimoto C.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: Vol 447 Issue: 4 Pages: 609-15
- DOI
  10.1016/j.bbrc.2014.04.037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-14J12067, KAKENHI-PROJECT-24591442, KAKENHI-PROJECT-26830114, KAKENHI-PROJECT-26860760
[Journal Article] Clinical significance of soluble CD26 in malignant pleural mesothelioma2014
- Author(s)
  Fujimoto N, Ohnuma K, Aoe K, Hosono O, Yamada T, Kishimoto T, Morimoto C
- Journal Title
  
  PLoS One
  
  Volume: Dec 19 Pages: 9-12
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26670486
[Journal Article] Bilateral Entry and Release of Middle East Respiratory Syndrome-Coronavirus Induces Profound Apoptosis of Human Bronchial Epithelial Cells.2013
- Author(s)
  Tao X, Hill TE, Morimoto C, Peters CJ, Ksiazek TG, Tseng CT.
- Journal Title
  
  J Virol.
  
  Volume: 87 Issue: 17 Pages: 9953-8
- DOI
  10.1128/jvi.01562-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659401
[Journal Article] Prevention of acute graft-versus-host disease by humanized anti-CD26 monoclonal antibody2013
- Author(s)
  Hatano R, Ohnuma K, Yamamoto J, Dang NH, Yamada T, Morimoto C
- Journal Title
  
  Br J Haematol
  
  Volume: 162 Issue: 2 Pages: 263-77
- DOI
  10.1111/bjh.12378
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21679005, KAKENHI-PROJECT-23390086, KAKENHI-PROJECT-24659401, KAKENHI-PROJECT-25670195
[Journal Article] CD26-mediated co-stimulation in human CD8^+ T cells provokes effector function via pro-inflammatory cytokine production2013
- Author(s)
  Hatano R, Ohnuma K, Yamamoto J, Dang NH, Morimoto C
- Journal Title
  
  Immunology
  
  Volume: 138 Issue: 2 Pages: 165-172
- DOI
  10.1111/imm.12028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21679005, KAKENHI-PROJECT-22390200, KAKENHI-PROJECT-24659401
[Journal Article] CD26 Expression on T-anaplastic large cell lymphoma (ALCL) line Karpas 299 is associated with increased expression of versican and MT1-MMP and enhanced adhesion2013
- Author(s)
  Havre P, Ohnuma K, Iwata S, Morimoto C, Dang NH.
- Journal Title
  
  BMC Cancer
  
  Volume: 5 Issue: 1 Pages: 517-517
- DOI
  10.1186/1471-2407-13-517
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21679005, KAKENHI-PROJECT-24591442, KAKENHI-PROJECT-24659401
[Journal Article] CD9 negatively regulates CD26 expression and inhibits CD26-mediated enhancement of invasive potential of malignant mesothelioma cells2013
- Author(s)
  Okamoto T, Iwata S, Yamazaki H, Hatano R, Komiya E, Dang NH, Ohnuma K, Morimoto C
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 1 Pages: e86671-e86671
- DOI
  10.1371/journal.pone.0086671
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21679005, KAKENHI-PROJECT-24591442, KAKENHI-PROJECT-24659401
[Journal Article] Nuclear localization of CD26 induced by a humanized monoclonal antibody inhibits tumor cell growth by modulating of POLR2A transcription2013
- Author(s)
  Yamada K, Hayashi M, Madokoro H, Nishida H, Du W, Ohnuma K, Sakamoto M, Morimoto C, Yamada T
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 4 Pages: e62304-e62304
- DOI
  10.1371/journal.pone.0062304
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21679005, KAKENHI-PROJECT-24659401, KAKENHI-PROJECT-25430157, KAKENHI-PROJECT-25670195
[Journal Article] Multiple effects of repetitive transcranial magnetic stimulation on neuropsychiatric disorders.2013
- Author(s)
  Ikeda T, Morimoto C, et al.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: in press Issue: 2 Pages: 121-7
- DOI
  10.1016/j.bbrc.2013.03.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390200, KAKENHI-PROJECT-24659401
[Journal Article] Inhibition of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Infection by Anti-CD26 Monoclonal Antibody.2013
- Author(s)
  Ohnuma K, Haagmans BL, Hatano R, Raj VS, Mou H, Iwata S, Dang NH, Bosch BJ, Morimoto C.
- Journal Title
  
  J Virol.
  
  Volume: 87 Pages: 13892-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659401
[Journal Article] Inhibition of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Infection by Anti-CD26 Monoclonal Antibody2013
- Author(s)
  Ohnuma K, Haagman BL, Hatano R, Raj VS, Mou H, Iwata S, Dang NH, Bosch BJ, Morimoto C
- Journal Title
  
  J Virology
  
  Volume: 87 Issue: 24 Pages: 13892-13899
- DOI
  10.1128/jvi.02448-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21679005, KAKENHI-PROJECT-24591442, KAKENHI-PROJECT-24659401
[Journal Article] Polyarthropathy in type 2 diabetes patients treated with DPP4 inhibitors2013
- Author(s)
  Saito T, Ohnuma K, Dang NH, Hatano R, Ninomiya H, Morimoto C
- Journal Title
  
  Diabetes Res Clin Pract
  
  Volume: 102 Issue: 1 Pages: e8-e12
- DOI
  10.1016/j.diabres.2013.07.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21679005, KAKENHI-PROJECT-24659401
[Journal Article] Polyarthropathy in type 2 diabetes patients treated with DPP4 inhibitors2013
- Author(s)
  Saito T, Ohnuma K, Suzuki H, Dang NH, Hatano R, Ninomiya H, Morimoto C.
- Journal Title
  
  Diabetes Res Clin Pract
  
  Volume: 102
- Data Source
  KAKENHI-PROJECT-24659401
[Journal Article] CD9 expression as a favorable prognostic marker for patients with malignant mesothelioma.2012
- Author(s)
  Amatya VJ, Morimoto C, et al.
- Journal Title
  
  Oncol Rep.
  
  Volume: 29 Issue: 1 Pages: 21-28
- DOI
  10.3892/or.2012.2116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390200, KAKENHI-PROJECT-24659401
[Journal Article] Characterization of cancer stem cell properties of CD24 and CD26-positive human malignant mesothelioma cells2012
- Author(s)
  Yamazaki H, Naito M, Ghani F, Dang NH, Iwata S, Morimoto C
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 419 Issue: 3 Pages: 529-536
- DOI
  10.1016/j.bbrc.2012.02.054
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591278, KAKENHI-PROJECT-22390200, KAKENHI-PROJECT-22650223
[Journal Article] Cardiomyocyte-Specific Overexpression of HEXIM1 Prevents Right Ventricular Hypertrophy in Hypoxia-Induced Pulmonary Hypertension in Mice.2012
- Author(s)
  Yoshikawa N, Morimoto C, et al.
- Journal Title
  
  PLoS One.
  
  Volume: 7 Issue: 12 Pages: e52522-e52522
- DOI
  10.1371/journal.pone.0052522
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390200, KAKENHI-PROJECT-23791050, KAKENHI-PROJECT-24390236, KAKENHI-PROJECT-24659401, KAKENHI-PROJECT-24659471, KAKENHI-PUBLICLY-24116510
[Journal Article] Impact of the Integrin Signaling Adaptor Protein NEDD9 on Prognosis and Metastatic Behavior of Human Lung Cancer.2012
- Author(s)
  Kondo S, Morimoto C, et al.
- Journal Title
  
  Clin Cancer Res.
  
  Volume: 18 Issue: 22 Pages: 6326-6338
- DOI
  10.1158/1078-0432.ccr-11-2162
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390200, KAKENHI-PROJECT-23591434, KAKENHI-PROJECT-24390236, KAKENHI-PROJECT-24591442, KAKENHI-PROJECT-24659401, KAKENHI-PROJECT-24659471
[Journal Article] CD26 Overexpression is associated with prolonged survival and enhanced chemosensitivity in malignant pleural mesothelioma2012
- Author(s)
  Aoe K, Amatya VJ, Fujimoto N, Ohnuma K, Hosono O, Hiraki A, Fujii M, Yamada T, Dang NH, Takeshima Y, Inai K, Kishimoto T, Morimoto C
- Journal Title
  
  Clin Cancer Res
  
  Volume: 18(5) Issue: 5 Pages: 1447-1456
- DOI
  10.1158/1078-0432.ccr-11-1990
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21679005, KAKENHI-PROJECT-22390200, KAKENHI-PROJECT-22650223, KAKENHI-PROJECT-23591434
[Journal Article] Regulation of cancer stem cell properties by CD9 in human B-acute lymphoblastic leukemia2011
- Author(s)
  Yamazaki H, Inukai T, et al
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 409 Issue: 1 Pages: 14-21
- DOI
  10.1016/j.bbrc.2011.04.098
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591356, KAKENHI-PROJECT-22390200, KAKENHI-PROJECT-22650223
[Journal Article] Crosstalk between Glucocorticoid Receptor and Nutritional Sensor mTOR in Skeletal Muscle2011
- Author(s)
  S himizu N, Yoshikawa N, Ito N, Maruyama T, Suzuki Y, Takeda S, Nakae J, Tagata Y, Nishitani S, Takehana K, Sano M, Fukuda K, Suematsu M, Morimoto C, Tanaka H
- Journal Title
  
  Cell Metab
  
  Volume: 13 Issue: 2 Pages: 170-182
- DOI
  10.1016/j.cmet.2011.01.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300149, KAKENHI-PROJECT-22390200, KAKENHI-PROJECT-22650223, KAKENHI-PROJECT-22790693
[Journal Article] Dipeptidyl peptidase in autoimmune pathophysiology.2011
- Author(s)
  Ohnuma K, Hosono O, Dang NH, Morimoto C.
- Journal Title
  
  Adv Clin Chem.
  
  Volume: 53 Pages: 51-51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650223
[Journal Article] Crosstalk between glucocorticoid receptor and nutritional sensor mTOR in skeletal muscle.2011
- Author(s)
  Shimizu N, Yoshikawa N, Ito N, Maruyama T, Suzuki Y, Takeda S, Nakae J, Tagata Y, Nishitani S, Takehana K, Sano M, Fukuda K, Suematsu M, Morimoto C, Tanaka H.
- Journal Title
  
  Cell Metab.
  
  Volume: 13 Pages: 170-182
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650223
[Journal Article] Diet-induced adipose tissue inflammation and liver steatosis are prevented by DPP-4 inhibition in diabetic mice2011
- Author(s)
  Shirakawa J, Fujii H, Ohnuma K, Sato K, Ito Y, Kaji M, Sakamoto E, Koganei M, Sasaki H, Nagashima Y, Amo K, Aoki K, Morimoto C, Takeda E, Terauchi Y
- Journal Title
  
  Diabetes
  
  Volume: 60(4) Issue: 4 Pages: 246-1257
- DOI
  10.2337/db10-1338
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-09J03269, KAKENHI-PROJECT-21300277, KAKENHI-PROJECT-21679005, KAKENHI-PROJECT-22390200, KAKENHI-PROJECT-22590437, KAKENHI-PROJECT-22650223, KAKENHI-PROJECT-23591315
[Journal Article] Dipeptidyl peptidase in autoimmune pathophysiology2011
- Author(s)
  Ohnuma K, Hosono O, Dang NH, Morimoto C.
- Journal Title
  
  Adv Clin Chem.
  
  Volume: 53 Pages: 51-51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390200
[Journal Article] Identification of cancer stem cell markers in human malignant mesothelioma cells.2011
- Author(s)
  Ghani FI, Yamazaki H, Iwata S, Okamoto T, Aoe K, Okabe K, Mimura Y, Fujimoto N, Kishimoto T, Yamada T, Xu CW, Morimoto C.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 404 Pages: 735-742
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650223
[Journal Article] Mechanisms of confluence-dependent expression of CD26 in coloncancer cell lines.2011
- Author(s)
  Abe M, Havre PA, Urasaki Y, Ohnuma K , Morimoto C, Dang LH, Dang NH.
- Journal Title
  
  BMC Cancer.
  
  Volume: 11 Pages: 51-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650223
[Journal Article] Mechanisms of confluence-dependent expression of CD26 in colon cancer cell lines.2011
- Author(s)
  Abe M, Havre PA, Urasaki Y, Ohnuma K, Morimoto C, Dang LH, Dang NH.
- Journal Title
  
  BMC Cancer.
  
  Volume: 11 Pages: 51-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390200
[Journal Article] Identification of cancer stem cell markers in human malignant mesothelioma cells.2011
- Author(s)
  Ghani FI, Yamazaki H, Iwata S, Okamoto T, Aoe K, Okabe K, Mimura Y, Fujimoto N, Kishimoto T, Yamada T, Xu CW, Morimoto C.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 404 Pages: 735-742
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390200
[Journal Article] Mechanisms of confluence-dependent expression of CD26 in colon cancer cell lines2011
- Author(s)
  Abe M, Havre PA, Urasaki Y, Ohnuma K, Morimoto C, Dang LH, Dang NH
- Journal Title
  
  BMC Cancer
  
  Volume: 11 Issue: 1 Pages: 51-51
- DOI
  10.1186/1471-2407-11-51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21679005, KAKENHI-PROJECT-22390200, KAKENHI-PROJECT-22650223
[Journal Article] Overexpression of CD26/DPPIV in mesothelioma tissue and mesothelioma cell lines2011
- Author(s)
  Amatya VJ, Takeshima Y, Kushitani K, Yamada T, Morimoto C, Inai K
- Journal Title
  
  Oncol Rep
  
  Volume: 26 Pages: 1369-1375
- DOI
  10.3892/or.2011.1449
- NAID
  120005300470
- Data Source
  KAKENHI-PROJECT-22390200, KAKENHI-PROJECT-22650223
[Journal Article] Identification of cancer stem cell markers in human malignant mesothelioma cells2011
- Author(s)
  Ghani FI, Yamazaki H, Iwata S, Okamoto T, Aoe K, Okabe K, Mimura Y, Fujimoto N, Kishimoto T, Yamada T, Xu CW, Morimoto C
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 404 Pages: 735-42
- Data Source
  KAKENHI-PROJECT-22650223
[Journal Article] Targeted therapy by monoclonal antibodies.2011
- Author(s)
  Ohnuma K, Morimoto C.
- Journal Title
  
  Nippon Rinsho.
  
  Volume: 68 Pages: 1841-1847
- NAID
  40017319588
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650223
[Journal Article] Crosstalk between glucocorticoid receptor and nutritional sensor mTOR in skeletal muscle.2011
- Author(s)
  Shimizu N, Yoshikawa N, Ito N, Maruyama T, Suzuki Y, Takeda S, Nakae J, Tagata Y, Nishitani S, Takehana K, Sano M, Fukuda K, Suematsu M, Morimoto C, Tanaka H.
- Journal Title
  
  Cell Metab.
  
  Volume: 13 Pages: 170-182
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390200
[Journal Article] Diet-Induced Adipose Tissue Inflammation and Liver Steatosis Are Prevented by DPP-4 Inhibition in Diabetic Mice.2011
- Author(s)
  Shirakawa J, Fujii H, Ohnuma K, Sato K, Ito Y, Kaji M, Sakamoto E, Koganei M, Sasaki H, Nagashima Y, Amo K, Aoki K, Morimoto C, Takeda E, Terauchi Y.
- Journal Title
  
  Diabetes.
  
  Volume: 60 Pages: 1246-1257
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390200
[Journal Article] Targeted therapy by monoclonal antibodies.2011
- Author(s)
  Ohnuma K, Morimoto C.
- Journal Title
  
  Nippon Rinsho.
  
  Volume: 68 Pages: 1841-1847
- NAID
  40017319588
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390200
[Journal Article] Microscopic polyangiitis initiated with liver dysfunction, calf pain and fever of unknown origin.2010
- Author(s)
  Ohnuma K, Hosono O, Katayose T, Yoshikawa N, Kawasaki H, Fujii T, Oyaizu N, Tanaka H, Morimoto C
- Journal Title
  
  Rheumatol Int. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Inhibition of dipeptidyl peptidase 4 regulates microvascular endothelial growth induced by inflammatory cytokines.2010
- Author(s)
  Takasawa W, Ohnuma K, Hatano R, Endo Y, Dang NH, Morimoto C.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 401 Pages: 7-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650223
[Journal Article] Optimal stimulation for CD70 induction on human monocyte-derived dendritic cells and the importance of CD70 in naive CD4 (+) T-cell differentiation2010
- Author(s)
  Arimoto-Miyamoto K, Kadowaki N, Kitawaki T, Iwata S, Morimoto C, Uchiyama T.
- Journal Title
  
  Immunology
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Optimal stimulation for CD70 induction on human monocyte-derived dendritic cells and the importance of CD70 in naive CD4(+) T-cell differentiation2010
- Author(s)
  Arimoto-Miyamoto K, Kadowaki N, Kitawaki T, Iwata S, Morimoto C, Uchiyama T
- Journal Title
  
  Immunology
  
  Volume: 130 Issue: 1 Pages: 137-49
- DOI
  10.1111/j.1365-2567.2010.03220.x
- Data Source
  KAKENHI-PROJECT-22650223
[Journal Article] Aqueous extract of Carica papaya leaves exhibits anti-tumor activity and immunomodulatory effects.2010
- Author(s)
  Otsuki N, Dang NH, Kumagai E, Kondo A, Iwata S, Morimoto C.
- Journal Title
  
  J Ethnopharmacol.
  
  Volume: 127 Pages: 760-767
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390200
[Journal Article] Optimal stimulation for CD70 induction on human monocyte-derived dendritic cells and the importance of CD70 in naive CD4(+)T-cell differentiation2010
- Author(s)
  Arimoto-Miyamoto K, Kadowaki N, Kitawaki T, Iwata S, Morimoto C, Uchiyama T.
- Journal Title
  
  Immunology. (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20013010
[Journal Article] Optimal stimulation for CD70 induction on human monocyte-derived dendritic cells and the importance of CD70 in naive CD4(+) T-cell differentiation.2010
- Author(s)
  Arimoto-Miyamoto K, Kadowaki N, Kitawaki T, Iwata S, Morimoto C, Uchiyama T.
- Journal Title
  
  Immunology
  
  Volume: 130 Pages: 137-149
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390200
[Journal Article] Inhibition of dipeptidyl peptidase 4 regulates microvascular endothelial growth induced by inflammatory cytokines.2010
- Author(s)
  Takasawa W, Ohnuma K, Hatano R, Endo Y, Dang NH, Morimoto C.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 401 Pages: 7-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390200
[Journal Article] Optimal stimulation for CD70 induction on human monocyte-deriveddendritic cells and the importance of CD70 in naive CD4(+) T-cell differentiation.2010
- Author(s)
  Arimoto-Miyamoto K, Kadowaki N, Kitawaki T, Iwata S, Morimoto C, Uchiyama T.
- Journal Title
  
  Immunology.
  
  Volume: 130 Pages: 137-149
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650223
[Journal Article] Aqueous extract of Carica papaya leaves exhibits anti-tumor activity and immunomodulatory effects.2010
- Author(s)
  Otsuki N, Dang NH, Kumagai E, Kondo A, Iwata S, Morimoto C.
- Journal Title
  
  J Ethnopharmacol.
  
  Volume: 127 Pages: 760-767
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650223
[Journal Article] Targeted therapy by monoclonal antibodies2010
- Author(s)
  Ohnuma K, Morimoto C
- Journal Title
  
  Nippon Rinsho
  
  Volume: 68 Pages: 1841-7
- NAID
  40017319588
- Data Source
  KAKENHI-PROJECT-22390200
[Journal Article] Inhibition of dipeptidyl peptidase 4 regulates micro-vascular endothelial growth induced by inflammatory cytokines2010
- Author(s)
  Takasawa W, Ohnuma K, Hatano R, Endo Y, Dang NH, Morimoto C
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 40 Issue: 1 Pages: 7-12
- DOI
  10.1016/j.bbrc.2010.08.112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21679005, KAKENHI-PROJECT-22390200, KAKENHI-PROJECT-22650223
[Journal Article] Targeted therapy by monoclonal antibodies2010
- Author(s)
  Ohnuma K, Morimoto C
- Journal Title
  
  Nippon Rinsho
  
  Volume: 68 Pages: 1841-7
- NAID
  40017319588
- Data Source
  KAKENHI-PROJECT-22650223
[Journal Article] Optimal stimulation for CD70 induction on human monocyte-derived dendritic cells and the importance of CD70 in naive CD4(+) T-cell differentiation.2010
- Author(s)
  Arimoto-Miyamoto K, Kadowaki N, Kitawaki T, Iwata S, Morimoto C, Uchiyama T
- Journal Title
  
  Immunology. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] An adult case of Henoch-Schonlein purpura complicating common peroneal nerve mononeuropathy2009
- Author(s)
  Ohnuma K, Hosono O, Kawasaki H, Yoshikawa N, Katayose T, Oyaizu N, Tanaka H, Morimoto C.
- Journal Title
  
  Mod Rheumatol. 19
  
  Pages: 73-9
- NAID
  10025112125
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] CD90 and CD110 correlate with cancer stem cell potentials in human T-acute lymphoblastic leukemia cells.2009
- Author(s)
  Yamazaki H, Nishida H, Iwata S, Dang NH, Morimoto C
- Journal Title
  
  Biochem Biophys Res Commun. 383
  
  Pages: 172-177
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Microscopic polyangiitis initiated with liver dysfunction, calf pain and fever of unknown origin2009
- Author(s)
  Ohnuma K, Hosono O, Katayose T, Yoshikawa N, Kawasaki H, Fujii T, Oyaizu N, Tanaka H, Morimoto C.
- Journal Title
  
  Rheumatol Int.
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] The CD70-CD27 interaction during the stimulation with dendritic cells promotes naive CD4+ T cells to develop into T cells producing a broad array of immunostimulatory cytokines in humans2009
- Author(s)
  Hashimoto-Okada M, Kitawaki T, Kadowaki N, Iwata S, Morimoto C, Hori T, Uchiyama T.
- Journal Title
  
  Int Immunol. 21
  
  Pages: 891-904
- NAID
  10025387511
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] CD9 correlates with cancer stem cell potentials in human B-acute lymphoblastic leukemia cells2009
- Author(s)
  Yo K, Iwata S, Hashizume Y, Kondo S, Nomura S, Hosono O, Kawasaki H, Tanaka H, Dang NH, Morimoto C.
- Journal Title
  
  Biochem Biophys Res Commun. 382
  
  Pages: 210-214
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20013010
[Journal Article] An adult case of Henoch-Schonlein purpura complicating common peroneal nerve mononeuropathy.2009
- Author(s)
  Ohnuma K, Hosono O, Kawasaki H, Yoshikawa N, Katayose T, Oyaizu N, Tanaka H, Morimoto C
- Journal Title
  
  Mod Rheumatol. 19
  
  Pages: 73-79
- NAID
  10025112125
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Caveolin-1 is a novel immunohistochemical marker to differentiate epithelioid mesothelioma from lung adenocarcinoma2009
- Author(s)
  Amatya VJ, Takeshima Y, Kohno H, Kushitani K, Yamada T, Morimoto C, Inai K.
- Journal Title
  
  Histopathology 55
  
  Pages: 10-19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20013010
[Journal Article] CD9 correlates with cancer stem cell potentials in human B-acute lymphoblastic leukemia cells2009
- Author(s)
  Nishida H, Yamazaki H, Yamada T, Iwata S, Dang NH, Inukai T, Sugita K, Ikeda Y, Morimoto C.
- Journal Title
  
  Biochem Biophys Res Commun. 382
  
  Pages: 57-62
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20013010
[Journal Article] The CD70-CD27 interaction during the stimulation with dendritic cells promotes naive CD4+T cells to develop into T cells producing a broad array of immunostimulatory cytokines in humans.2009
- Author(s)
  Hashimoto-Okada M, Kitawaki T, Kadowaki N, Iwata S, Morimoto C, Hori T, Uchiyama T
- Journal Title
  
  Int Immunol. 21
  
  Pages: 891-904
- NAID
  10025387511
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] SHP-2 inhibits tyrosine phosphorylation of Cas-L and regulates cell migration2009
- Author(s)
  Yo K, Iwata S, Hashizume Y, Kondo S, Nomura S, Hosono O, Kawasaki H, Tanaka H, Dang NH, Morimoto C.
- Journal Title
  
  Biochem Biophys Res Commun (Electronic)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20013010
[Journal Article] Histamine H1-receptor antagonists with immunomodulating activities : potential use for modulating T helper type 1(Th1)/Th2 cytokine imbalance and inflammatory responses in allergic diseases2009
- Author(s)
  Okamoto T, Iwata S, Ohnuma K, Dang NH, Morimoto C.
- Journal Title
  
  Clin Exp Immunol. 157
  
  Pages: 27-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20013010
[Journal Article] Caveolin-1 is a novel immunohistochemical marker to differentiate epithelioid mesothelioma from lung adenocarcinoma.2009
- Author(s)
  Amatya VJ, Takeshima Y, Kohno H, Kushitani K, Yamada T, Morimoto C, Inai K
- Journal Title
  
  Histopathology. 55
  
  Pages: 10-19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Localization of CD26/DPPIV in nucleus and its nuclear translocation enhanced by anti-CD26 monoclonal antibody with anti-tumor effect2009
- Author(s)
  Yamada K, Hayashi M, Du W, Ohnuma K, Sakamoto M, Morimoto C, Yamada T.
- Journal Title
  
  Cancer Cell Int.
  
  Pages: 9-17
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] CD90 and CD110 correlate with cancer stem cell potentials in human T-acute lymphoblastic leukemia cells2009
- Author(s)
  Yamazaki H, Nishida H, Iwata S, Dang NH, Morimoto C.
- Journal Title
  
  Biochem Biophys Res Commun. 383
  
  Pages: 172-7
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] CD90 and CD110 correlate with cancer stem cell potentials in human T-acute lymphoblastic leukemia cells2009
- Author(s)
  Yamazaki H, Nishida H, Iwata S, Dang NH, Morimoto C.
- Journal Title
  
  Biochem Biophys Res Commun. 383
  
  Pages: 172-177
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20013010
[Journal Article] SHP-2 inhibits tyrosine phosphorylation of Cas-L and regulates cell migration2009
- Author(s)
  Yo K, Iwata S, Hashizume Y, Kondo S, Nomura S, Hosono O, Kawasaki H, Tanaka H, Dang NH, Morimoto C.
- Journal Title
  
  Biochem Biophys Res Commun. 382
  
  Pages: 210-4
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Localization of CD26/DPPIV in nucleus and its nuclear translocation enhanced by anti-CD26 monoclonal antibody with anti-tumor effect.2009
- Author(s)
  Yamada K, Hayashi M, Du W, Ohnuma K, Sakamoto M, Morimoto C, Yamada T.
- Journal Title
  
  Cancer Cell Int. 9
  
  Pages: 17-17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Localization of CD26/DPPN in nucleus and its nuclear translocation enhanced by anti-CD26 monoclonal antibody with anti-tumor effect2009
- Author(s)
  Yamada K, Hayashi M, Du W, Ohnuma K, Sakamoto M, Morimoto C, Yamada T.
- Journal Title
  
  Cancer Cell Int. 9
  
  Pages: 17-17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20013010
[Journal Article] CD26 expression on T cell lines increases SDF-1-alpha-mediated invasion2009
- Author(s)
  Havre PA, Abe M, Urasaki Y, Ohnuma K, Morimoto C, Dang NH.
- Journal Title
  
  Br J Cancer. 101
  
  Pages: 983-991
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20013010
[Journal Article] CD9 correlates with cancer stem cell potentials in human B-acute lymphoblastic leukemia cells2009
- Author(s)
  Nishida H, Yamazaki H, Yamada T. Iwata S, Dang NH, Inukai T, Sugita K. Ikeda Y, Morimoto C.
- Journal Title
  
  Biochem Biophys Res Commun (Electronic)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20013010
[Journal Article] BCAR12009
- Author(s)
  Iwata S, Morimoto C.
- Journal Title
  
  Targeted Protein Database 1 370(in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20013010
[Journal Article] CD9 correlates with cancer stem cell potentials in human B-acute lymphoblastic leukemia cells2009
- Author(s)
  Nishida H, Yamazaki H, Yamada T, Iwata S, Dang NH, Inukai T, Sugita K, Ikeda Y, Morimoto C.
- Journal Title
  
  Biochem Biophys Res Commun. 382
  
  Pages: 57-62
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Blockade of CD26-mediated T cell costimulation with soluble caveolin-1-Ig fusion protein induces anergy in CD4(+)T cells.2009
- Author(s)
  Ohnuma K, Uchiyama M, Hatano R, Takasawa W, Endo Y, Dang NH, Morimoto C
- Journal Title
  
  Biochem Biophys Res Commun. 386
  
  Pages: 327-332
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Histamine H1-receptor antagonists with immunomodulating activities : potential use for modulating T helper type 1 (Th1)/Th2 cytokine imbalance and inflammatory responses in allergic diseases.2009
- Author(s)
  Okamoto T, Iwata S, Ohnuma K, Dang NH, Morimoto C
- Journal Title
  
  Clin Exp Immunol. 157
  
  Pages: 27-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] CD9 correlates with cancer stem cell potentials in human B-acute lymphoblastic leukemia cells.2009
- Author(s)
  Yo K, Iwata S, Hashizume Y, Kondo S, Nomura S, Hosono O, Kawasaki H, Tanaka H, Dang NH, Morimoto C
- Journal Title
  
  Biochem Biophys Res Commun. 382
  
  Pages: 210-214
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] CD26 expression on T cell lines increases SDF-1-alpha-mediated invasion.2009
- Author(s)
  Havre PA, Abe M, Urasaki Y, Ohnuma K, Morimoto C, Dang NH
- Journal Title
  
  Br J Cancer. 101
  
  Pages: 983-991
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] The CD70-CD27 interaction during the stimulation with dendritic cells promotes naive CD4+ T cells to develop into T cells producing a broad array of immunostimulatory cytokines in humans2009
- Author(s)
  Hashimoto-Okada M, Kitawaki T, Kadowaki N, Iwata S, Morimoto C, Hori T, Uchiyama T.
- Journal Title
  
  Int Immunol. 21
  
  Pages: 891-904
- NAID
  10025387511
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20013010
[Journal Article] Histamine Hl-receptor antagonists with immunomodulating activities : potential use for modulating T helper type 1 (Th1)/Th2 cytokine imbalance and inflammatory responses in allergic diseases2009
- Author(s)
  Okamoto T, Iwata S, Ohnuma K, Dang NH, Morimoto C.
- Journal Title
  
  Clin Exp Immunol. 157
  
  Pages: 27-34
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] CD9 Correlates with cancer stem cell potentials in human B-acute lymphoblastic leutemes cells.2009
- Author(s)
  Hihida H, Yamazaki H, Yamada T, Iwata S, Dang NH, Imukai T, Sugita K, Ikeda Y, Morimoto C.
- Journal Title
  
  Biochem Biophys Res Commun in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Blockade of CD26-mediated T cell costimulation with soluble caveolin-1-Ig fusion protein induces anergy in CD4(+)T cells2009
- Author(s)
  Ohnuma K, Uchiyama M, Hatano R, Takasawa W, Endo Y, Dang NH, Morimoto C.
- Journal Title
  
  Biochem Biophys Res Commun. 386
  
  Pages: 327-332
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20013010
[Journal Article] CD9 correlates with cancer stem cell potentials in human B-acute lymphoblastic leukemia cells.2009
- Author(s)
  Nishida H, Yamazaki H, Yamada T, Iwata S, Dang NH, Inukai T, Sugita K, Ikeda Y, Morimoto C
- Journal Title
  
  Biochem Biophys Res Commun. 382
  
  Pages: 57-62
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Blockade of CD26-mediated T cell costimulation with soluble caveolin-1-Ig fusion protein induces anergy in CD4 (+) T cells2009
- Author(s)
  Ohnuma K, Uchiyama M, Hatano R, Takasawa W, Endo Y, Dang NH, Morimoto C.
- Journal Title
  
  Biochem Biophys Res Commun. 386
  
  Pages: 327-32
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] CD26 expression on T cell lines increases SDF-1-alpha-mediated invasion2009
- Author(s)
  Havre PA, Abe M, Urasaki Y, Ohnuma K, Morimoto C, Dang NH.
- Journal Title
  
  Br J Cancer. 101
  
  Pages: 983-91
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Caveolin-1 is a novel immunohistochemical marker to differentiate epithelioid mesothelioma from lung adenocarcinoma2009
- Author(s)
  Amatya VJ, Takeshima Y, Kohno H, Kushitani K, Yamada T, Morimoto C, Inai K.
- Journal Title
  
  Histopathology 55
  
  Pages: 10-9
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Role of CD26/dipepridyl peptidase IV in human T cell activation and function2008
- Author(s)
  Ohmuma k, Takahashi N, Yamochi T, Hodono O, Dang NH, Morimoto C.
- Journal Title
  
  Fromt Biosci 13
  
  Pages: 2299-2310
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Tissue- and context-dependent modulation of hormonal sensitivity of glucocorticoid-responsive genes gy hexamethylene bisacetamide-inducible protein 1.2008
- Author(s)
  Shimizu M, Yoshikawa N, Morimoto C, Tanaka H, et al
- Journal Title
  
  Mol Endocrinol. 22
  
  Pages: 2609-2623
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Revisiting an old acquaintance : CD26 and its molecular mechanisms in T cell function2008
- Author(s)
  Ohnuma K, Dang NH, Morimoto C.
- Journal Title
  
  Trends Immunol. 29
  
  Pages: 295-301
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Comparative study of regulaltory Tcell function of human CD25CD4 T cells from thymocytes, cord blood, and adult peripheral blood.2008
- Author(s)
  Fujimaki W, Takahashi N, Ohmuma K, Makatsu M, Kurosawa H, Yodhida S, Dang NH, Uchiyama T, Morimoto C.
- Journal Title
  
  Clin Dev Immunol. 2008
  
  Pages: 305859-305859
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] The role of CD26/dipeptidyl peptidase IV in cancer2008
- Author(s)
  Havre PA, Morimoto C, Dang NH, et. al.
- Journal Title
  
  Front Biosci 13
  
  Pages: 1634-1645
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Role of CD26/dipeptidyl peptidase IV in human T cell activation and function.2008
- Author(s)
  Ohnuma K, Hosono O, Dang NH, Morimoto C, et. al.
- Journal Title
  
  Front Biosci. 13
  
  Pages: 2299-2310
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18013017
[Journal Article] Role of the hinge region of glucocorticoid receptor for HEXIM1-mediated transcriptional repression2008
- Author(s)
  Yoshikawa N, Shimizu N, Sano M, Ohnuma K, Iwata S, Hosono O, Fukuda K, Morimoto C, Tanaka H.
- Journal Title
  
  Biochem Biophys Res Commun. 371
  
  Pages: 44-9
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Role of CD26/dipeptidyl peptidase IV in human T cell activation and function2008
- Author(s)
  Ohnuma K, Takahashi N, Yamochi T, Hosono O, Dang NH, Morimoto C.
- Journal Title
  
  Front Biosci. 13
  
  Pages: 2299-310
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Role of the hinge region of glucocorticoid receptor for HEXIMI-mediated trans criprional repression.2008
- Author(s)
  Yohikawa N, Shimizu N, Sano M, Ohmuma K, Iwata S, Hosono O, Fukuda K, Morimoto C, Taanaka H.
- Journal Title
  
  Biochem Biophys Res Commun. 371
  
  Pages: 44-49
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Comparative study of regulatory T cell function of human CD25CD4 T cells from thymocytes, cord blood, and adult peripheral blood2008
- Author(s)
  Fujimaki W, Takahashi N, Ohnuma K, Nagatsu M, Kurosawa H, Yoshida S, Dang NH, Uchiyama T, Morimoto C.
- Journal Title
  
  Clin Dev Immunol. 2008
  
  Pages: 305859-305859
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] The role of CD26/dipeptidyl peptidase IV in cancer.2008
- Author(s)
  Havre PA, Morimoto C, Dang NH, et. al.
- Journal Title
  
  Front Biosci. 13
  
  Pages: 1634-1645
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18013017
[Journal Article] Effect of H-1-receptor antagonists on proliferative response, cytokine production, and cellular migration of human T cells and macrophages2008
- Author(s)
  Iwata S, Nori M, Hashizume Y, You K, Morimoto C.
- Journal Title
  
  Clinical and Experimental Allergy Reviews 8
  
  Pages: 21-29
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20013010
[Journal Article] Role of CD26/dipeptidyl peptidase IV in human T cell activation and function2008
- Author(s)
  Ohnuma K, Hosono O, Dang NH, Morimoto C, et. al.
- Journal Title
  
  Front Biosci 13
  
  Pages: 2299-2310
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Revisiting an old acquaintance:CD26 and its molecular mechanisms in T cell function2008
- Author(s)
  Ohmuma K, Morimoto C.
- Journal Title
  
  Trends Immunol 29
  
  Pages: 295-301
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] SSA/Ro52 autoantigen interacts with Dcp2 to enhance its decapping activity2008
- Author(s)
  Yamochi T, Ohnuma K, Hosono O, Tanaka H, Kanai Y, Morimoto C.
- Journal Title
  
  Biochem Biophys Res Commun. 370
  
  Pages: 195-9
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Fibromectin promotes cell proliferation of human pre-B cell line via irs interactions with VLA-4 and VLA-52008
- Author(s)
  Harima A, Morimoto C, Harigara K, Saito Y,et al
- Journal Title
  
  Hematology 13
  
  Pages: 236-243
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] The role of CD26/dipeptidyl peptidase IV in cancer2008
- Author(s)
  Havre PA, Abe M, Urasaki Y, Ohnuma K, Morimoto C, Dang NH.
- Journal Title
  
  Front Biosci. 13
  
  Pages: 1634-45
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Tissue- and context-dependent modulation of hormonal sensitivity of glucocorticoid-responsive genes by hexamethylene bisacetamide-inducible protein 12008
- Author(s)
  Shimizu N, Yoshikawa N, Wada T, Handa H, Sano M, Fukuda K, Suematsu M, Sawai T, Morimoto C, Tanaka H.
- Journal Title
  
  Mol Endocrinol. 22
  
  Pages: 2609-23
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Fibronectin promotes cell proliferation of human pre-B cell line via its interactions with VLA-4 and VLA-52008
- Author(s)
  Harima A, Nakaseko C, Yokota A, Kitagawa M, Morimoto C, Harigaya K, Saito Y.
- Journal Title
  
  Hematology 13
  
  Pages: 236-43
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Transcriptional upregulation of ipas gene expression by HIF-1: A negative feedback regulatory circuit in HIF-1-mediated signaling in hypoxic cells.2007
- Author(s)
  Makino Y, Uenishi R, Okamoto K, Isoe T, Hosono O, Tanaka H, Kanopka A, Poellinger L, Haneda M, Morimoto C.
- Journal Title
  
  J Biol Chem. 282
  
  Pages: 14073-82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659209
[Journal Article] Stem cell properties and the side population cells as a target for interferon-alpha in adult T-cell leukemia/lymphoma.2007
- Author(s)
  Kayo H, Yamazaki H, Nishida H, Dang NH, Morimoto C.
- Journal Title
  
  Biochem Biophys Res Commun. 364
  
  Pages: 808-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18013017
[Journal Article] Knockdown of XAB2 enhances all-trans retionic acid-induced cellular differentiation in all-trans retinoic acid-sensitive and -resistant cancer cells2007
- Author(s)
  Ohnuma-Ishikawa K, Morimoto C, et al.
- Journal Title
  
  Cancer Res. 67
  
  Pages: 1019-29
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] CD26 Plays a Role in Malignant Mesothelioma Tumor Growth and is a novel Target for Treatment of Malignant Mesothelioma2007
- Author(s)
  Inamoto T, Morimoto C, et al.
- Journal Title
  
  Clin Cancer Res. in press
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Knockdown of XAB2 enhances all-trans retinoic acid-induced cellular differentiation in all-trans retinoic acid-sensitive and -resistant cancer cells2007
- Author(s)
  Ohnuma-Ishikawa K, Morimoto C, et al.
- Journal Title
  
  Cancer Res. 67
  
  Pages: 1019-1029
- Data Source
  KAKENHI-PROJECT-18013017
[Journal Article] Crk-associated substrate lymphocyte type regulates transforming growth factor-beta signaling by inhibiting Smad6 and Smad72007
- Author(s)
  Inamoto S, morimoto C, et al.
- Journal Title
  
  Oncogene 26
  
  Pages: 893-904
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Knockdown of XAB2 enhances all-trans retinoic acid-induced cellular differentiation in all-trans retinoic acid-sensitive and -resistant cancer cells2007
- Author(s)
  Ohnuma-Ishikawa K, Morio T, Yamada T, Sugawara Y, Ono M, Nagasawa M, Yasuda A, Morimoto C, Ohnuma K, Dang NH, Hosoi H, Verdin E, Mizutani S.
- Journal Title
  
  Cancer Res. 67
  
  Pages: 1019-29
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] CD26 Plays a Role in Malignant Mesothelioma Tumor Growth and is a Novel Target for the Treatment of Malignant Mesothelioma2007
- Author(s)
  Inamoto T, Morimoto C, et al.
- Journal Title
  
  Clin Cancer Res. (in press)
- Data Source
  KAKENHI-PROJECT-18013017
[Journal Article] Transcriptional upregulation of ipas gene expression by HIF-1 : A negative feedback regulatory circuit in HIF-1-mediated signaling in hypoxic cells2007
- Author(s)
  Makino Y, Morimoto C, et al.
- Journal Title
  
  J Biol Chem. in press
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Transcriptional upregulation of ipas gene expression by HIF-1: A negative feedback regulatory circuit in HIF-1-mediated signaling in hypoxic cells2007
- Author(s)
  Makino Y, Morimoto C, et. al.
- Journal Title
  
  J Biol Chem. 282
  
  Pages: 14073-14082
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18013017
[Journal Article] Caveolin-1 triggers T-cell activation via CD26 in association with CARMAl2007
- Author(s)
  Ohnuma K, Morimoto C, et al.
- Journal Title
  
  J Biol Chem. 282
  
  Pages: 10117-31
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Crk-associated substrate lymphocyte type regulates transforming growth factor-beta signaling by inhibiting Smad6 and Smad72007
- Author(s)
  Inamoto S, Morimoto C, et al.
- Journal Title
  
  Oncogene 26
  
  Pages: 893-904
- Data Source
  KAKENHI-PROJECT-18013017
[Journal Article] Could serum antibody to poly (ADP-ribose) and/or histone H1 be marker for senile dementia of Alzheimer type?2007
- Author(s)
  Kanai Y, Akatsu H, Iizuka H, Morimoto C.
- Journal Title
  
  Ann N Y Acad Sci. 1109
  
  Pages: 338-344
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18013017
[Journal Article] Transcriptional upregulation of ipas gene expression by HIF-1:A negative feedback regulatory circuit in HIF-1-mediated signaling in hypoxic cells2007
- Author(s)
  Makino Y, Morimoto C, et. al.
- Journal Title
  
  J Biol Chem 282
  
  Pages: 14073-14082
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Stem cell properties and the side population cells as a target for interferon-alpha in adult T-cell leukemia/lymphoma2007
- Author(s)
  Kayo H, Yamazaki H, Nishida H, Dang NH, Morimoto C.
- Journal Title
  
  Biochem Biophys Res Commun. 364
  
  Pages: 808-14
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Humanized Anti-CD26 monoclonal antibody as a treatment for malignant mesothelioma tumors2007
- Author(s)
  Inamoto T, Yamada T, Ohnuma K, Kina S, Takahashi N, Yamochi T, Inamoto S, Katsuoka Y, Hosono O, Tanaka H, Dang NH, Morimoto C.
- Journal Title
  
  Clin Cancer Res. 13
  
  Pages: 4191-200
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Transcriptional upregulation of ipas gene expression by HIF-1 : A negative feedback regulatory circuit in HIF-1-mediated signaling in hypoxic cells2007
- Author(s)
  Makino Y, Morimoto C, et al.
- Journal Title
  
  J Biol Chem. (in press)
- Data Source
  KAKENHI-PROJECT-18013017
[Journal Article] Humanized Anti-CD26 monoclonal antibody as a treatment for malignant mesothelioma tumors2007
- Author(s)
  Inamoto T, Morimoto C, et. al.
- Journal Title
  
  Clin Cancer Res. 13
  
  Pages: 4191-4200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18013017
[Journal Article] Could serum antibody to poly (ADP-ribose) and/or histone H1 be marker for senile dementia of Alzheimer type?2007
- Author(s)
  Kanai Y, Akatsu H, Iizuka H, Morimoto C.
- Journal Title
  
  Ann N Y Acad Sci. 1109
  
  Pages: 338-44
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Transcriptional upregulation of ipas gene expression by HIF-1 : A negative feedback regulatory circuit in HIF-1-mediated signaling in hypoxic cells2007
- Author(s)
  Makino Y, Uenishi R, Okamoto K, Isoe T, Hosono O, Tanaka H, Kanopka A, Poellinger L, Haneda M, Morimoto C.
- Journal Title
  
  J Biol Chem. 282
  
  Pages: 14073-82
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Caveolin-1 triggers T-cell activation via CD26 in association with CARMA12007
- Author(s)
  Ohnuma K, Morimoto C, et al.
- Journal Title
  
  J Biol Chem. 282
  
  Pages: 10117-10131
- Data Source
  KAKENHI-PROJECT-18013017
[Journal Article] CD26/dipeptidyl peptidase IV as a novel therapeutic target for cancer and immune disorders.2007
- Author(s)
  Thompson MA, Ohnuma K, Abe M, Morimoto C, Dang NH
- Journal Title
  
  Mini Rev Med Chem. 7
  
  Pages: 253-73
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659209
[Journal Article] Caveolin-1 triggers T-cell activation via CD26 in association with CARMA12007
- Author(s)
  Ohnuma K, Uchiyama M, Yamochi T, Nishibashi K, Hosono O, Takahashi N, Kina S, Tanaka H, Lin X, Dang NH, Morimoto C.
- Journal Title
  
  J Biol Chem. 282
  
  Pages: 10117-31
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Stem cell properties and the side population cells as a target for interferon-alpha in adult T-cell leukemia/Imhoma2007
- Author(s)
  Kayo H, Yamazaki H, Nishida H, Dang NH, Morimoto C
- Journal Title
  
  Biochem Biophys Res Commun 364
  
  Pages: 808-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Humanized Anti-CD26 monoclonal antibody as a treatment for malignant mesothelioma tumors.2007
- Author(s)
  Inamoto T, Yamada T, Ohnuma K, Kina S, Takahashi N, Yamochi T, Inamoto S, Katsuoka Y, Hosono O, Tanaka H, Dang NH, Morimoto C.
- Journal Title
  
  Clin Cancer Res. 13
  
  Pages: 4191-200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659209
[Journal Article] Could serum antibody to poly(ADP-ribose)and/or histone Hl be marker for senile dementia of Alzheimer type?2007
- Author(s)
  Kanai Y, Akatsu H, Iizuka H, Morimoto C
- Journal Title
  
  Ann N Y Acad Sci 1109
  
  Pages: 338-344
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Crk-associated substrate lymphocyte type regulates transforming growth factor-beta signaling by inhibiting Smad6 and Smad72007
- Author(s)
  Inamoto S, Iwata S, Inamoto T, Nomura S, Sasaki T, Urasaki Y, Hosono O, Kawasaki H, Tanaka H, Dang NH, Morimoto C.
- Journal Title
  
  Oncogene 26
  
  Pages: 893-904
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Anti-CD26 monoclonal antibody-mediated GI-S arrest of human renal clear cell carcinoma Caki-2 is associated with retinoblastoma substrate dephosphorylation, cyclin-dependent kinase 2 reduction, p27(kipl)enhancement,and disruption of binding to the extracellular matrix2006
- Author(s)
  Inamoto T, Morimoto C, et al.
- Journal Title
  
  Clin cancer Res. 12
  
  Pages: 3470-7
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Anti-CD26 monoclonal antibody-mediated G1-S arrest of human renal clear cell carcinoma Caki-2 is associated with retinoblastoma substrate dephosphorylation, cyclin-dependent kinase 2 reduction, p27(kip1) enhancement, and disruption of binding to the extracellular matrix2006
- Author(s)
  Inamoto T, Morimoto C, et al.
- Journal Title
  
  Clin Cancer Res. 12
  
  Pages: 3470-3477
- Data Source
  KAKENHI-PROJECT-18013017
[Journal Article] Anti-CD26 monoclonal antibody-mediated G1-S arrest of human renal clear cell carcinoma Caki-2 is associated with retinoblastoma substrate dephosphorylation, cyclin-dependent kinase 2 reduction, p27 (kipl) enhancement, and disruption of binding to the extracellular matrix2006
- Author(s)
  Inamoto T, Yamochi T, Ohnuma K, Iwata S, Kina S, Inamoto S, Tachibana M, Katsuoka Y, Dang NH, Morimoto C.
- Journal Title
  
  Clin Cancer Res. 12
  
  Pages: 3470-7
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] CD26 mediates dissociation of Tollip and IRAK-1 from caveolin-1 and induces upregulation of CD86 on antigen-presenting cells2005
- Author(s)
  Ohnuma K, Yamochi T, Uchiyama M, Nishibashi K, Iwata S, Hosono O, Kawasaki H, Tanaka H, Dang NH, Morimoto C.
- Journal Title
  
  Mol Cell Biol. 25
  
  Pages: 7743-57
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] CD26 regulates p38 mitogen-activated protein kinase-dependent phosphorylation of integrin betal, adhesion to extracellular matrix, and tumorigenicity of T-anaplastic large cell lymphoma Karpas 2992005
- Author(s)
  Sato T, Yamochi T, Yamochi T, Aytac, Ohnuma K, McKee KS, Morimoto C, Dang NH.
- Journal Title
  
  Cancer Res. 65
  
  Pages: 6950-6
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Regulation of p38 phosphorylation and topoisomerase llalpha expression in the B-cell lymphoma line jiyoye by CD26/dipeptidyl peptidase IV is associated with enhanced in vitro and in vivo sensitivity to doxorubicin.2005
- Author(s)
  Yamochi T, Morimoto C, et al.
- Journal Title
  
  Cancer Res. 65
  
  Pages: 1973-1983
- Data Source
  KAKENHI-PROJECT-16659261
[Journal Article] Nedd9 protein, a Cas-L homologue, is upregulated after transient global ischemia in rats : possible involvement of Nedd9 in the differentiation of neurons after ischemia2005
- Author(s)
  Sasaki T, Iwata S, Okano HJ, Urasaki Y, Hamada J, Tanaka H, Dang NH, Okano H, Morimoto C.
- Journal Title
  
  Stroke 36
  
  Pages: 2457-62
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Nedd9 protein, a Cas-L homologue, is upregulated after transient global ischemia in rats : possible involvement of Nedd9 in the differentiation of neurons after ischemia2005
- Author(s)
  Sasaki T, Morimoto C, et al.
- Journal Title
  
  Stroke 36
  
  Pages: 2457-2462
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] CD26 T cells in the pathogenesis of asthma.2005
- Author(s)
  Ohnuma K, Yamochi T, Hosono O, Morimoto C.
- Journal Title
  
  Clin Exp Immunol. 139
  
  Pages: 13-16
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] CD26 T cells in the pathogenesis of asthma2005
- Author(s)
  Ohnuma K, Yamochi T, Hosono O, Morimoto C.
- Journal Title
  
  Clin Exp Immunol. 139
  
  Pages: 13-16
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Roxithromycin specifically inhibits development of collagen induced arthritis and production of proinflammatory cytokines by human T cells and macrophages.2005
- Author(s)
  Urasaki Y, Morimoto C, et al.
- Journal Title
  
  J Rheumatol 32
  
  Pages: 1765-1774
- Data Source
  KAKENHI-PROJECT-16659261
[Journal Article] Regulation of p38 phosphorylation and topoisomerase IIalpha expression in the B-cell lymphoma line Jiyoye by CD26/dipeptidyl peptidase IV is associated with enhanced in vitro and in vivo sensitivity to doxorubicin2005
- Author(s)
  Yamochi T, Yamochi T, Aytac U, Sato T, Sato K, Ohnuma K, McKee KS, Morimoto C, Dang NH.
- Journal Title
  
  Cancer Res. 65
  
  Pages: 1973-83
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] HTLV-I Tax induces and associates with Crk-associated substrate lymphocyte type (Cas-L)2005
- Author(s)
  Iwata S, Souta-Kuribara A, Yamakawa A, Sasaki T, Shimizu T, Hosono O, Kawasaki H, Tanaka H, Dang NH, Watanabe T, Arima N, Morimoto C.
- Journal Title
  
  Oncogene 24
  
  Pages: 1262-71
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Nedd9 protein, a Cas-L homologue, is upregulated after transient global ischemia in rats : possible involvement of Nedd9 in the differentiation of neurons after ischemia2005
- Author(s)
  Sakaki T, Morimoto C, et al.
- Journal Title
  
  Stroke 36
  
  Pages: 2457-2462
- Data Source
  KAKENHI-PROJECT-16659261
[Journal Article] CD26 mediates dissociation of Tollip and IRAK-1 from caveolin-1 and induces upregulation of CD86 on antigen-presenting cells.2005
- Author(s)
  Ohnuma K, Morimoto C, et al.
- Journal Title
  
  Mol Cell Biol. 25
  
  Pages: 7743-7757
- Data Source
  KAKENHI-PROJECT-17014028
[Journal Article] CD26 mediates dissociation of Tollip and IRAK-1 from caveolin-1 and induces upregulation of CD86 on antigen-presenting cells.2005
- Author(s)
  Ohnuma K, Morimoto C, et al.
- Journal Title
  
  Mol Cell Biol. 25
  
  Pages: 7743-7757
- Data Source
  KAKENHI-PROJECT-16659261
[Journal Article] Roxithromycin specifically inhibits development of collagen induced arthritis and production of proinflammatory cytokines by human T cells and macrophages.2005
- Author(s)
  Urasaki Y, Morimoto C, et al.
- Journal Title
  
  J Rheumatol 32
  
  Pages: 1765-1774
- Data Source
  KAKENHI-PROJECT-17014028
[Journal Article] HTLV-I Tax induces and associates with Ork-associated substrate lymphocyte type (Cas-L).2005
- Author(s)
  Iwata S, Morimoto C, et al.
- Journal Title
  
  Oncogene 24
  
  Pages: 1262-1271
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] CD26 mediates dissociation of Tollip and IRAK-1 from caveolin-1 and induces upregulation of CD86 on antigen-presenting cells.2005
- Author(s)
  Ohnuma K, Morimoto C, et al.
- Journal Title
  
  Mol Cell Biol. 25
  
  Pages: 7743-7757
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Regulation of p38 phosphorylation and topoisomerase llalpha expression in the B-cell lymphoma line Jiyoye by CD26/dipeptidyl peptidase IV is associated with enhanced in vitro and in vivo sensitivity to doxorubicin.2005
- Author(s)
  Yamochi T, Morimoto C, et al.
- Journal Title
  
  Cancer Res. 65
  
  Pages: 1973-1983
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] HTLV-I Tax induces and associates with Crk-associated substrate lymphocyte type(Cas-L).2005
- Author(s)
  Iwata S, Morimoto C, et al.
- Journal Title
  
  Oncogene 24
  
  Pages: 1262-1271
- Data Source
  KAKENHI-PROJECT-16659261
[Journal Article] Regulation of p38 phosphorylation and topoisomerase llalpha expression the B-cell lymphoma line Jiyoye by CD26/dipeptidyl peptidase IV is associated with enhanced in vitro and in vivo sensitivity to doxorubicin.2005
- Author(s)
  Yamochi T, Morimoto C, et al.
- Journal Title
  
  Cancer Res. 65
  
  Pages: 1973-1983
- Data Source
  KAKENHI-PROJECT-17014028
[Journal Article] Nedd9 protein, a Cas-L homologue, is upregulated after transient global ischemia in rats : possible involvement of Nedd9 in the differentiation of neurons after ischemia2005
- Author(s)
  Sasaki T, Morimoto C, et al.
- Journal Title
  
  Stroke 36
  
  Pages: 2457-2462
- Data Source
  KAKENHI-PROJECT-17014028
[Journal Article] HTLV-I Tax induces and associates with Crk-associated substrate lymphocyte type (Cas-L).2005
- Author(s)
  Iwata S, Morimoto C, et al.
- Journal Title
  
  Oncogene 24
  
  Pages: 1262-1271
- Data Source
  KAKENHI-PROJECT-17014028
[Patent] 抗癌剤への抵抗性改善剤.2021
- Inventor(s)
  森本幾夫、大沼圭、波多野良、伊藤匠、金子有太郎.
- Industrial Property Rights Holder
  ワイズ・エー・シー株式会社、学校法人順天堂
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Overseas
- Data Source
  KAKENHI-PROJECT-20H03471
[Patent] 抗CD26抗体と免疫チェックポイント阻害剤との併用療法.2021
- Inventor(s)
  森本幾夫、波多野良、大沼圭、金子有太郎.
- Industrial Property Rights Holder
  ワイズ・エー・シー株式会社、学校法人順天堂
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-091761
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-20H03471
[Patent] 抗癌剤への抵抗性改善剤2020
- Inventor(s)
  森本幾夫、大沼圭、波多野良、伊藤匠、金子有太郎
- Industrial Property Rights Holder
  ワイズ・エー・シー株式会社、学校法人順天堂
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-099449
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-20H03471
[Patent] 抗癌剤への抵抗性改善剤2020
- Inventor(s)
  森本幾夫、大沼圭、伊藤匠、波多野良、金子有太郎
- Industrial Property Rights Holder
  ワイズ・エー・シー株式会社、学校法人順天堂
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-099449
- Filing Date
  2020
- Overseas
- Data Source
  KAKENHI-PROJECT-18H02782
[Patent] 免疫チェックポイント阻害剤2019
- Inventor(s)
  大沼圭、森本幾夫、波多野良
- Industrial Property Rights Holder
  大沼圭、森本幾夫、波多野良
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-004480
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-18H02782
[Patent] 免疫チェックポイント阻害剤2019
- Inventor(s)
  大沼圭、森本幾夫、波多野良
- Industrial Property Rights Holder
  学校法人順天堂
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-004480
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-16H05345
[Patent] 抗ヒトCD26モノクローナル抗体2018
- Inventor(s)
  森本幾夫、波多野良、山田健人、大沼圭
- Industrial Property Rights Holder
  学校法人順天堂，学校法人埼玉医科大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-049308
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-16H05345
[Patent] 抗ヒトIL-26抗体2017
- Inventor(s)
  森本幾夫、波多野良、大沼圭、伊藤匠
- Industrial Property Rights Holder
  学校法人順天堂
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-231439
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-16H05345
[Patent] 抗ヒトIL-26抗体2017
- Inventor(s)
  森本幾夫、波多野良、大沼圭、伊藤匠
- Industrial Property Rights Holder
  学校法人順天堂
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-231439
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-15H04879
[Patent] CD26抗体と他の抗がん剤とを組み合わせた癌治療用組成物2015
- Inventor(s)
  山田健人，林睦、山田幸司、森本幾夫、岡本俊博、金子有太郎
- Industrial Property Rights Holder
  山田健人，林睦、山田幸司、森本幾夫、岡本俊博、金子有太郎
- Industrial Property Rights Type
  特許
- Filing Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-26670486
[Patent] 免疫抑制剤2014
- Inventor(s)
  森本幾夫、大沼圭、波多野良
- Industrial Property Rights Holder
  順天堂大学
- Industrial Property Rights Type
  特許
- Filing Date
  2014-09-29
- Data Source
  KAKENHI-PROJECT-26670486
[Patent] 抗ヒト化CD26モノクローナル抗体又はその抗原結合性断片2013
- Inventor(s)
  森本幾夫、大沼圭、波多野良、山田健人
- Industrial Property Rights Holder
  順天堂大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-158533
- Filing Date
  2013-07-31
- Data Source
  KAKENHI-PROJECT-24659401
[Patent] MERSコロナウイルス感染予防治療剤2013
- Inventor(s)
  森本幾夫、大沼圭
- Industrial Property Rights Holder
  順天堂大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-187124
- Filing Date
  2013-09-17
- Overseas
- Data Source
  KAKENHI-PROJECT-24659401
[Patent] 細胞表面分子CD26を標的とした悪性中皮腫の治療法2007
- Inventor(s)
  森本幾夫, 大沼圭, 稲元輝生
- Industrial Property Rights Holder
  国立大学法人東京大学
- Filing Date
  2007-03-14
- Data Source
  KAKENHI-PROJECT-17109011
[Patent] 免疫調整剤のスクリーニング方法2006
- Inventor(s)
  森本幾夫, 大沼圭
- Industrial Property Rights Holder
  国立大学法人東京大学
- Industrial Property Number
  2006-351173
- Filing Date
  2006-12-17
- Data Source
  KAKENHI-PROJECT-17109011
[Patent] caveolin-1-Fc γ1融合タンパク質及びその使用2006
- Inventor(s)
  森本幾夫, 大沼圭
- Industrial Property Rights Holder
  国立大学法人東京大学
- Industrial Property Number
  2006-351154
- Filing Date
  2006-12-27
- Data Source
  KAKENHI-PROJECT-17109011
[Patent] caveolin-1-Fcγ 1融合タンパク質及びその使用2006
- Inventor(s)
  森本幾夫, 大沼圭
- Industrial Property Rights Holder
  東京大学
- Industrial Property Number
  2006-351154
- Filing Date
  2006-12-27
- Data Source
  KAKENHI-PROJECT-17109011
[Presentation] CD26/DPPIV regulates mechanical alloknesis at the periphery.2021
- Author(s)
  Komiya E, Tominaga M, Hatano R, Itoh T, Honda K, Toyama S, Kamata Y, Otsuka H, Ohnuma K, Morimoto C, Takamori K.
- Organizer
  11th World Congress on Itch (WCI), 口頭発表, Web開催
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03471
[Presentation] CD26/dipeptidyl-peptidase IVは機械的かゆみの調節因子である.2021
- Author(s)
  古宮栄利子, 冨永光俊, 波多野良, 外山扇雅, 伊藤匠, 鎌田弥生, 本田耕太郎, 大沼圭, 森本幾夫, 高森建二.
- Organizer
  第26回日本病態プロテアーゼ学会, 口頭発表, Web開催
- Data Source
  KAKENHI-PROJECT-20H03471
[Presentation] Anti-interleukin-26 therapy for the control of chronic inflammation in GVHD.2021
- Author(s)
  Hatano R, Otsuka H, Itoh T, Saeki H, Yamamoto A, Shirakawa Y, Iyama S, Iwao N, Sato T, Yamada T, Morimoto C, Ohnuma K.
- Organizer
  第83回日本血液学会, 口頭発表, Web開催
- Data Source
  KAKENHI-PROJECT-20H03471
[Presentation] 加齢皮膚におけるアロネーシスの発症機構の解明.2021
- Author(s)
  古宮栄利子, 小島豪, 冨永光俊, 森本幾夫, 髙森建二.
- Organizer
  第17回加齢皮膚医学研究会, 口頭発表, Web開催
- Data Source
  KAKENHI-PROJECT-20H03471
[Presentation] Mu-opioid ligand endomorphin induces alloknesis at the periphery.2021
- Author(s)
  Komiya E, Tominaga M, Hatano R, Itoh T, Honda K, Toyama S, Kamata Y, Otsuka H, Ohnuma K, Morimoto C, Takamori K.
- Organizer
  第46回日本研究皮膚科学会, 口頭発表, Web開催
- Data Source
  KAKENHI-PROJECT-20H03471
[Presentation] 9.Endomorphin preferentially induces mechanical alloknesis under the control of DPPIV enzyme2020
- Author(s)
  Eriko Komiya, Ryo Hatano, Takumi Itoh, Kotaro Honda, Yayoi Kamata, Sumika Toyama, Catharina Sagita Moniaga, Haruna Otsuka, Nobuaki Takahashi, Kei Ohnuma, Mitsutoshi Tominaga, Chikao Morimoto, Kenji Takamori
- Organizer
  The 45th Annual Meeting of the Japanese Society for Investigative Dermatology
- Data Source
  KAKENHI-PROJECT-18H02782
[Presentation] Endomorphin preferentially induces mechanical alloknesis under the control of DPPIV enzyme.2020
- Author(s)
  Eriko Komiya, Ryo Hatano, Takumi Itoh, Kotaro Honda, Yayoi Kamata, Sumika Toyama, Catharina Sagita Moniaga, Haruna Otsuka, Nobuaki Takahashi, Kei Ohnuma, Mitsutoshi Tominaga, Chikao Morimoto, Kenji Takamori.
- Organizer
  The 45th Annual Meeting of the Japanese Society for Investigative Dermatology
- Data Source
  KAKENHI-PROJECT-20H03471
[Presentation] 加齢皮膚で誘発される機械的かゆみ調節機構の解明2019
- Author(s)
  古宮栄利子、冨永光俊、波多野良、伊藤匠、大塚春奈、本田耕太郎、外山扇雅、鎌田弥生、大沼圭、森本幾夫、髙森建二
- Organizer
  第15回加齢皮膚医学研究会
- Data Source
  KAKENHI-PROJECT-16H05345
[Presentation] CD26分子はDPPⅣ酵素活性によって乾癬のかゆみを調節する2018
- Author(s)
  古宮栄利子、波多野良、大塚春奈、伊藤匠、大沼圭、冨永光俊、森本幾夫、髙森建二
- Organizer
  第33回日本乾癬学会学術大会
- Data Source
  KAKENHI-PROJECT-16H05345
[Presentation] 全身性エリテマトーデスのステロイド減量困難例におけるCD26陰性T細胞サブセットの増加について2018
- Author(s)
  波多野良、大沼圭、石井智徳、伊藤匠、岩田哲史、奥村康、関川巖、森本幾夫
- Organizer
  第62回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-16H05345
[Presentation] Anti-CD26 Humanized Monoclonal Antibody Conjugated To Triptolide Inhibits Mesothelioma Cell Growth Via Transportation Into Nucleus And Impaired RNA Polymerase II2018
- Author(s)
  Yamada T, Madokoro H, Yamada K, Nishida H,　Morimoto C,　Sakamoto M, Hayashi M
- Organizer
  The 6th JCA-AACR Special Joint Conference,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05345
[Presentation] 急性GVHDマウスモデルにおけるHMGB1の動態に関する検討2018
- Author(s)
  岩尾憲明、大沼圭、大塚春奈、波多野良、古宮栄利子、伊藤匠、森本幾夫
- Organizer
  第40回日本造血細胞移植学会
- Data Source
  KAKENHI-PROJECT-16H05345
[Presentation] Anti-CD26 humanized antibody-triptolide conjugate moves into nucleus and impairs RNA polymeraseⅡ2018
- Author(s)
  山田健人、間所裕子、西田浩子、森本幾夫、坂元亨宇、林睦
- Organizer
  第107回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-16H05345
[Presentation] 難治性自己免疫疾患における新規炎症性サイトカインIL-26の役割と分子標的療法の開発2018
- Author(s)
  伊藤匠、波多野良、岩田哲史、大沼圭、森本幾夫
- Organizer
  第62回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-16H05345
[Presentation] 全身性エリテマトーデスのステロイド減量困難例における CD26陰性T細胞サブセットの増加について2018
- Author(s)
  波多野良, 大沼圭, 石井智徳, 伊藤匠, 岩田哲史, 奥村康, 関川巖, 森本幾夫
- Organizer
  第62回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-18H02782
[Presentation] 機械的かゆみの調節メカニズムの解明2018
- Author(s)
  古宮栄利子、波多野良、大塚春奈、伊藤匠、松田浩則、須賀康、大沼圭、冨永光俊、森本幾夫、髙森建二
- Organizer
  第82回日本皮膚科学会東京支部
- Data Source
  KAKENHI-PROJECT-16H05345
[Presentation] CD26/DPPⅣはエンドモルフィンによる機械的かゆみを制御する2018
- Author(s)
  古宮栄利子、波多野良、伊藤匠、松田浩則、大沼圭，森本幾夫、冨永光俊、髙森建二
- Organizer
  第28回国際痒みシンポジウム
- Data Source
  KAKENHI-PROJECT-16H05345
[Presentation] 乾癬における新規炎症性サイトカインIL-26の役割と分子標的療法の開発2018
- Author(s)
  伊藤匠、波多野良、古宮栄利子、大塚春奈、冨永光俊、髙森建二、森本幾夫、大沼圭
- Organizer
  第33回日本乾癬学会学術大会
- Data Source
  KAKENHI-PROJECT-16H05345
[Presentation] 難治性自己免疫疾患における新規炎症性サイトカインIL-26の役割と分子標的療法の開発2018
- Author(s)
  伊藤匠, 波多野良, 大沼圭, 岩田哲史, 奥村康, 森本幾夫
- Organizer
  第62回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-18H02782
[Presentation] Interleukin-26-targeted therapy for the control of chronic GVHD.2018
- Author(s)
  Ryo Hatano, Haruna Otsuka, Eriko Komiya, Takumi Itoh, Noriaki Iwao, Taketo Yamada, Chikao Morimoto, KeiOhnuma.
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05345
[Presentation] Interleukin-26-targeted therapy for the control of chronic GVHD2018
- Author(s)
  Hating R, Otsuka H, Komiya E, Itoh T, Iwao I, Yamada T, Morimoto C, Ohnuma K.
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18H02782
[Presentation] The regulation of pruritus in psoriasis and atopic dermatitis-a possible role for CD26/DPPIV.2017
- Author(s)
  Eriko Komiya, Ryo Hatano, Haruna Otsuka, Takumi Itoh, Hiroto Yamazaki, Taketo Yamada, Yasushi Suga, Utako Kimura, Mitsutoshi Tominaga, Kenji Takamori, Kei Ohnuma, Chikao Morimoto.
- Organizer
  9th World Congress on Itch
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05345
[Presentation] 全身性エリテマトーデスのステロイド治療抵抗性とCD26陰性T細胞サブセットとの関係性について2017
- Author(s)
  波多野良、大沼圭、石井智徳、岩田哲史、奥村康、関川嚴、森本幾夫
- Organizer
  日本リウマチ学会総会
- Data Source
  KAKENHI-PROJECT-15H04879
[Presentation] 急性GVHDマウスモデルにおけるHMGB1の動態に関する検討2017
- Author(s)
  岩尾憲明、大沼圭、大塚春奈、波多野良、古宮栄利子、伊藤匠、森本幾夫
- Organizer
  日本造血幹細胞移植学会総会
- Data Source
  KAKENHI-PROJECT-15H04879
[Presentation] 全身性エリテマトーデスのステロイド治療抵抗性とCD26陰性T細胞サブセットとの関係性について.2017
- Author(s)
  波多野良、大沼圭、石井智徳、岩田哲史、奥村康、関川巖、森本幾夫.
- Organizer
  第61回日本リウマチ学会
- Data Source
  KAKENHI-PROJECT-16H05345
[Presentation] Anti-CD26 humanized monoclonal antibody conjugated to triptolide is transported into nucleus and impairs RNA polymerase II.2017
- Author(s)
  Yamada T, Madokoro H, Nishida H,　Morimoto C,　Sakamoto M, Hayashi M.
- Organizer
  生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-16H05345
[Presentation] IL-26 facilitates angiogenesis and skin inflammation via inducing FGF2 production in a murine model of imiquimod-induced psoriasis.2017
- Author(s)
  Takumi Itoh, Ryo Hatano, Haruna Otsuka, Noriaki Iwao, Satoshi Iwata, Taketo Yamada, Chikao Morimoto.
- Organizer
  第46回日本免疫学会
- Data Source
  KAKENHI-PROJECT-16H05345
[Presentation] CD26/DPPIV regulates mechanical itch in a mechanistically distinct manner from chemical itch2017
- Author(s)
  Eriko Komiya, Ryo Hatano, Haruna Otsuka, Takumi Itoh, Hiroto Yamazaki, Mitsutoshi Tominaga, Kenji Takamori, Kei Ohnuma, Chikao Morimoto.
- Organizer
  第42回日本研究皮膚科学会
- Data Source
  KAKENHI-PROJECT-16H05345
[Presentation] Humanized anti-CD26 monoclonal antibody, YS110, has anti-myeloma efficacy for the treatment of high-risk multiple myeloma.2017
- Author(s)
  Nishida H, Hayashi M, Morimoto C, Sakamoto M, Yamada T.
- Organizer
  The 59th American Society of Hematology Annual Meeting and Exposition.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05345
[Presentation] Humanized anti-CD26 monoclonal antibody has a therapeutic potentiality against multiple myeloma.2017
- Author(s)
  Nishida H, Hayashi M, Morimoto C, Sakamoto M, Yamada T.
- Organizer
  第79回日本血液学会
- Data Source
  KAKENHI-PROJECT-16H05345
[Presentation] CD26/DPPIV-mediated regulation of pruritus in psoriasis.2016
- Author(s)
  Komiya E, Hatano R, Otsuka H, Itoh T, Yamada T, Tomonaga M, Takamori K, Ohnuma K, Morimoto C.
- Organizer
  第41回研究皮膚科学会　年次学術大会・総会
- Place of Presentation
  仙台市
- Year and Date
  2016-12-09
- Data Source
  KAKENHI-PROJECT-15H04879
[Presentation] 乾癬においてCD26/DPPIVはsubstance Pを切断してかゆみを調節する2016
- Author(s)
  古宮栄利子、波多野良、大塚春奈、伊藤匠、山田健人、冨永光俊、高森健二、大沼圭、森本幾夫
- Organizer
  第31回日本乾癬学会学術大会
- Place of Presentation
  宇都宮市
- Year and Date
  2016-09-02
- Data Source
  KAKENHI-PROJECT-15H04879
[Presentation] CD26陽性T細胞サブセットに基づく全身性エリテマトーデスの病態解析2016
- Author(s)
  波多野良、大沼圭、石井智徳、岩田哲史、奥村康、関川巖、森本幾夫
- Organizer
  第60回日本リウマチ学会総会・学術集会
- Place of Presentation
  横浜市
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-15H04879
[Presentation] CD26の機能と治療応2016
- Author(s)
  森本幾夫
- Organizer
  中皮腫シンポジウム
- Place of Presentation
  兵庫医科大学
- Year and Date
  2016-10-29
- Invited
- Data Source
  KAKENHI-PROJECT-16H05345
[Presentation] T細胞共刺激分子CD26に基づく全身性エリテマトーデスの病態および疾患活動性の新規バイオマーカーの探索2015
- Author(s)
  波多野良, 大沼圭, 石井智徳, 岩田哲史, 奥村康, 関川巖, 森本幾夫
- Organizer
  第59回日本リウマチ学会総会
- Place of Presentation
  名古屋市
- Year and Date
  2015-04-23
- Data Source
  KAKENHI-PROJECT-15H04879
[Presentation] CD26 promotes invasiveness of malignant pleural mesothelioma cell via upregulation of periosti2015
- Author(s)
  古宮栄利子, 山崎裕人, 山田健人, 森本幾夫
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  愛知県名古屋市
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26670486
[Presentation] CD26の機能と治療応用2015
- Author(s)
  森本幾夫
- Organizer
  中皮腫シンポジウム
- Place of Presentation
  兵庫県神戸市
- Year and Date
  2015-12-26
- Invited
- Data Source
  KAKENHI-PROJECT-26670486
[Presentation] CD26 Is a Novel Target of Treatment for Tumor Progression and Its Related Bone Disease in Multiple Myelom2015
- Author(s)
  Nishida H, Morimoto C, Sakamoto M, Yamada T
- Organizer
  The 57th ASH Annual Meeting and Exposition
- Place of Presentation
  Orlando, FL, USA
- Year and Date
  2015-12-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670486
[Presentation] Clinical significance of soluble CD26 in malignant pleural mesotheliom2015
- Author(s)
  Fujimoto N, Ohnuma K, Aoe K, Hosono O, Yamada T, Kishimoto T, Morimoto C
- Organizer
  The 103th Annual Meeting of American Association of Cancer Research
- Place of Presentation
  Philadelphia, USA.
- Year and Date
  2015-04-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670486
[Presentation] First　-in-　human　phase I administration of YS110, a monoclonal antibody directed against the CD26 immunostimulatory molecule in advanced cancer patients2015
- Author(s)
  Angevin E, Isambert N,Trillet-Lenoir VN,You V, Alxandre J, Zalcman G, Viel P, Farace F, Valleix F, Podoll T, Kuramochi Y, Miyashita I, HosonoO, Dang NH, Ohnuma K, Yamada T, Kaneko Y, Morimoto C.
- Organizer
  The 2015 ASCO
- Place of Presentation
  Chicago, USA
- Year and Date
  2015-05-29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670486
[Presentation] T細胞共刺激分子CD26に基づく全身性エリテマトーデスの病態および疾患活動性の新規バイオマーカーの探索2015
- Author(s)
  波多野良，大沼圭，石井智徳，岩田哲史，奥村康，関川巖，森本幾夫
- Organizer
  第59回日本リウマチ学会総会・学術集会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Year and Date
  2015-04-25
- Data Source
  KAKENHI-PROJECT-24591442
[Presentation] T細胞共刺激分子CD26に基づく全身性エリテマトーデスの病態および疾患活動性の新規バイオマーカーの探索.2015
- Author(s)
  波多野良, 大沼圭, 石井智徳, 岩田哲史, 奥村康, 関川巖, 森本幾夫
- Organizer
  第59回日本リウマチ学会学術集会
- Place of Presentation
  愛知県名古屋市
- Year and Date
  2015-04-23
- Data Source
  KAKENHI-PROJECT-26670486
[Presentation] Antitumor activity of anti-CD26 humanized monoclonal antibody conjugated with triptolide via intranulear transportatio2015
- Author(s)
  林睦, 間所裕子, 山田幸司, 西田浩子, 坂元亨宇, 森本幾夫, 山田健人
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  愛知県名古屋市
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26670486
[Presentation] CD26抗体を基盤とするトランスレーショナルリサーチ2015
- Author(s)
  森本幾夫
- Organizer
  第57回日本小児血液・がん学会
- Place of Presentation
  山梨県山梨市
- Year and Date
  2015-11-27
- Invited
- Data Source
  KAKENHI-PROJECT-26670486
[Presentation] Clinical significance of soluble CD26 in malignant pleural mesothelioma2015
- Author(s)
  Fujimoto N, Ohｎuma K, Aoe K, Hosono O, Yamada T, Kishimoto T, Morimoto C
- Organizer
  16th World Conference of Lung Cancer
- Place of Presentation
  Denver, USA
- Year and Date
  2015-09-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670486
[Presentation] Anti-interleukin-26 therapy for lung fibrosis of GVHD2015
- Author(s)
  Ryo Hatano, Taketo Yamada, Haruna Otsuka, Eriko Komiya, Noriaki Iwao, Ko Okumura, Chikao Morimoto, Kei Ohnuma
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  金沢市
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-15H04879
[Presentation] First‐in‐Human Phase I administration of YS110, a humanized monoclonal antibody directed against the CD26 molecule in cancer patients.2012
- Author(s)
  Angevin E, Morimoto C, et al.
- Organizer
  37th The European Society for Medical Oncology (ESMO) Congress
- Place of Presentation
  Vienna, Austria
- Data Source
  KAKENHI-PROJECT-22390200
[Presentation] Humanized anti-CD26 mAb Leads to Prophylaxis and Treatment of GVHD in Hu-PBL-NOG Model Mice.2012
- Author(s)
  Hatano R, Morimoto C, et al.
- Organizer
  第74回日本血液学会学術集会
- Place of Presentation
  京都, 日本
- Data Source
  KAKENHI-PROJECT-22390200
[Presentation] Humanized anti-CD26 mAb Leads to Prophylaxis and Treatment of GVHD in Hu-PBL-NOG Model Mice.2012
- Author(s)
  Hatano R, Morimoto C, et al.
- Organizer
  第74回日本血液学会学術集会
- Place of Presentation
  京都, 日本
- Data Source
  KAKENHI-PROJECT-24659401
[Presentation] CD26 overexpression is associated with prolonged survival and enhanced chemosensitivity in malignant pleural mesothelioma.2012
- Author(s)
  Aoe K, Morimoto C, et al.
- Organizer
  11th International Conference of the International Mesothlioma Interest Group
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-22390200
[Presentation] CD26 overexpression is associated with prolonged survival and enhanced chemosensitivity in malignant pleural mesothelioma.2012
- Author(s)
  Aoe K, Morimoto C, et al.
- Organizer
  11th International Conference of the International Mesothlioma Interest Group
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-24659401
[Presentation] First‐in‐Human Phase I administration of YS110, a humanized monoclonal antibody directed against the CD26 molecule in cancer patients.2012
- Author(s)
  Angevin E, Morimoto C, et al.
- Organizer
  37th The European Society for Medical Oncology (ESMO) Congress
- Place of Presentation
  Vienna, Austria
- Data Source
  KAKENHI-PROJECT-24659401
[Presentation] Gene Targeting of an Integrin-Mediated Signaling Adaptor Molecule, Crk-Associated Substrate Lymphocyte Type Reduced the Severity of Collagen-Induced Arthritis. Its Possible Involvement in the Pathophysiology of Rheumatoid Arthritis.2012
- Author(s)
  Satoshi Iwata, Tomoki Katayose, Yoshiko Kichikawa, Hiromi Ichihara, Hiroshi Kawasaki, Osamu Hosono, Hirotoshi Tanaka and Chikao Morimoto.
- Organizer
  American College of Rheumatology Annual Meeting 2012
- Place of Presentation
  米国　ワシントン DC
- Data Source
  KAKENHI-PROJECT-24591442
[Presentation] The Current Status of Drug Development and the Role of Clinical Trial Centers in Japan2011
- Author(s)
  Chikao Morimoto
- Organizer
  International Symposium for Clinical Trial
- Place of Presentation
  Jeju, Korea(招待講演)
- Year and Date
  2011-10-07
- Data Source
  KAKENHI-PROJECT-22650223
[Presentation] The Current Status of Drug Development and the Role of Clinical Trial Centers in Japan2011
- Author(s)
  Chikao Morimoto
- Organizer
  International Symposium for Clinical Trial
- Place of Presentation
  Jeju, Korea(招待講演)
- Year and Date
  2011-10-07
- Data Source
  KAKENHI-PROJECT-22390200
[Presentation] The Current Status of Drug Development and the Role of Clinical Trial Centers in Japan2011
- Author(s)
  Morimoto C
- Organizer
  International Symposium of Clinical Trial
- Place of Presentation
  Jeju, Korea
- Year and Date
  2011-10-07
- Data Source
  KAKENHI-PROJECT-22650223
[Presentation] Stem Cell Characters and Drug Resistance of Cancer Stem Cell-Like Population in Human Acute Lymphoblastic Leukemia2009
- Author(s)
  Yamazaki H, Nishida H, Morimoto C.
- Organizer
  第7回国際幹細胞研究学会(ISSCR)
- Place of Presentation
  Center Conventions International Barcelona(Barcelona, Spain)
- Year and Date
  2009-07-10
- Data Source
  KAKENHI-PROJECT-20013010
[Presentation] A Novel Function of CD26-Madiate Costimulation in the Cytotoxic Activity of Human CD8+ T cells in Xenogeneic Chronic Graft-Versus-Host Disease (cGVHD) and GVL Mice Model2009
- Author(s)
  Hatano R, Ohnuma K, Yamada T, et al, Morimoto C.
- Organizer
  第51回アメリカ血液学会 (ASH)
- Place of Presentation
  Morial Convention Center (New Orleans, U. S. A.)
- Year and Date
  2009-12-07
- Data Source
  KAKENHI-PROJECT-17109011
[Presentation] CD26/DPPIVのヒトT細胞機能と活性化 : ベンチからベッドまで2009
- Author(s)
  森本幾夫, 大沼圭
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸国際展示場
- Year and Date
  2009-10-21
- Data Source
  KAKENHI-PROJECT-17109011
[Presentation] A Novel Function of CD26-Madiate Costimulation in the Cytotoxic Activity of Human CD8+T cells in Xenogeneic Chronic Graft-Versus-Host Disease(cGVHD)and GVL Mice Model.2009
- Author(s)
  Hatano R, Ohnuma K, Yamada T, et al, Morimoto C.
- Organizer
  第51回アメリカ血液学会(ASH)
- Place of Presentation
  Morial Convention Center(New Orleans, U.S.A.)
- Year and Date
  2009-12-07
- Data Source
  KAKENHI-PROJECT-17109011
[Presentation] CD26/DPP IVのヒトT細胞機能と活性化:ベンチからベッドまで2009
- Author(s)
  森本幾夫、大沼圭
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸国際展示場
- Year and Date
  2009-10-21
- Data Source
  KAKENHI-PROJECT-17109011
[Presentation] ヒト化CD26抗体の難治性免疫疾患(クローン病、GVHDなど)への治療法開発2008
- Author(s)
  森本幾夫
- Organizer
  厚生労働科学研究費補助金「基礎研究成果の臨床応用研究事業」トランスレーショナル研究成果発表会
- Place of Presentation
  (財)がん研究振興財団国際研究交流会館国際会議場
- Year and Date
  2008-02-26
- Data Source
  KAKENHI-PROJECT-17109011
[Presentation] ヒト化CD26抗体の難治性免疫疾患(クローン病、GVHDなど)への治療法開発2008
- Author(s)
  森本幾夫
- Organizer
  厚生労働科学研究費補助金「基礎研究成果の臨床応用研究事業」トランスレーショナル研究成果発表会
- Place of Presentation
  (財)がん研究振興財団国際研究交流会館国際会議場
- Year and Date
  2008-02-26
- Data Source
  KAKENHI-PROJECT-18013017
[Presentation] CD26分子を用いたトランスレーショナルリサーチ2008
- Author(s)
  森本幾夫
- Organizer
  第29回日本炎症・再生医学会教育講演
- Place of Presentation
  都市センターホテル
- Year and Date
  2008-07-09
- Data Source
  KAKENHI-PROJECT-17109011
[Presentation] 胸膜中皮腫における可溶性CD26の臨床有用性に関する検討
- Author(s)
  1)藤本伸一、青江啓介、細野治、山田健人、岸本卓巳、森本幾夫
- Organizer
  第73回日本癌学会学術集会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26670486
[Presentation] L-10産生誘導によるCD26共刺激経路のnegative feedback機構の解析
- Author(s)
  波多野良, 大沼圭, 岩田哲史, 石井智徳, 関川巖, 森本幾夫
- Organizer
  第58回日本リウマチ学会学術集会
- Place of Presentation
  グランドプリンスホテル新高輪（東京）
- Year and Date
  2014-04-24 – 2014-04-26
- Data Source
  KAKENHI-PROJECT-26670486
[Presentation] DPP4阻害剤の服用によって誘発される多関節症とそのバイオマーカー
- Author(s)
  1)大沼圭, 斉藤辰彦, 波多野良, 岩田哲史, 鈴木博史, 森本幾夫
- Organizer
  第58回日本リウマチ学会学術集会
- Place of Presentation
  グランドプリンスホテル新高輪（東京）
- Year and Date
  2014-04-24 – 2014-04-26
- Data Source
  KAKENHI-PROJECT-26670486
[Presentation] T細胞共刺激分子CD26を標的とした関節リウマチの新規アップストリーム治療法の開発について.
- Author(s)
  波多野良, 大沼圭, 森本幾夫
- Organizer
  第57回日本リウマチ学会学術集会
- Place of Presentation
  京都､日本
- Data Source
  KAKENHI-PROJECT-24659401

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Morimoto Chikao 森本 幾夫

MORIMOTO Chikao 森本 幾夫

Research Projects

Research Products

Co-Researchers

Molecular understanding of an innovative therapy for chronic inflammatory diseases targeting human Th17 cytokine IL-26Principal Investigator

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ヒト免疫特有の炎症性因子IL-26に基づく慢性炎症病態の解明と新規治療法の開発Principal Investigator

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Scientific research on development of anti-fibrotic agent targeting multi-organ profibrotic factor IL-26 in GVHD

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Molecular understanding of CD26-mediated immune regulatory mechanism and development of novel molecular targeted therapy for the treatment of refractory autoimmune diseasesPrincipal Investigator

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Mechanism of lung fibrosis in chronic GVHD

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Role of CD26 molecule in the infection of MERS(Middle East respiratory syndrome) virus and development of new therapyPrincipal Investigator

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Development of new therapeutic modalities for Rheumatoid Arthritis

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Association of deubiquitin ligase and cell surface molecules regulates the pathophysiology of malignant pleural mesotheliomaPrincipal Investigator

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Basic research of defining the function of CD26 on human immune system and its clinical application for autoimmune diseases.Principal Investigator

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To determine the epigenetic regulatory mechanism of cancer stem cells by cell surface molecules.Principal Investigator

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β1インテグリン及びその関連分子の癌転移・浸潤及び癌病態における意義の解析Principal Investigator

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Elucidation of intestinal mucosal immune system through the intracellular processing mechanisms of bacteria and its application for novel therapy of inflammatory bowel disease

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悪性中皮腫の発生機構及び病態の解明Principal Investigator

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Morimoto Chikao 森本幾夫

MORIMOTO Chikao 森本幾夫