Iwakura Yoichiro 岩倉洋一郎

… Alternative Names

Researcher Number	10089120
Other IDs
External Links
Affiliation (Current)	2020: 東京理科大学, 研究推進機構生命医科学研究所, 教授
Affiliation (based on the past Project Information) *help	2015 – 2020: 東京理科大学, 研究推進機構生命医科学研究所, 教授 2011 – 2016: 東京理科大学, 付置研究所, 教授 2012 – 2014: 東京理科大学, 生命医科学研究所, 教授 2012: 東京理科大学生命医科学研究所, 生命医科学研究所, 教授 1992 – 2011: 東京大学, 医科学研究所, 教授 … More
Review Section/Research Field	Principal Investigator Biological Sciences / Laboratory animal science / Laboratory animal science / Virology / Immunology / Immunology / Basic Section 49070:Immunology-related / Complex systems Except Principal Investigator Biological Sciences / Neuroscience in general … More
Keywords	Principal Investigator サイトカイン / 関節リウマチ / トランスジェニックマウス / ノックアウトマウス / HTLV-I / IL-1 / 自己免疫 / IL-6 / インターフェロン / 自己免疫疾患 … More Except Principal Investigator トランスジェニックマウス / ノックアウトマウス / サイトカイン / 癌遺伝子 / C型レクチン / 自然免疫 / 体外受精 / 生物機能モデル / ヒト疾患モデル / 形質転換動物 / マウス / ES細胞 / 相同遺伝子組換え / 胚培養 / 標的遺伝子組換え / 樹状細胞 / 真菌感染 / 遺伝子改変マウス / 受精 / 発癌遺伝子 / 成人性T細胞白血病 / T細胞受容体遺伝子再配列 / 哺乳動物初期胚 / 再構成卵巣 / 多段階発癌 / 遺伝子トラップ / キメラマウス / 遺伝子解析 / サル免疫不全ウイルス / ネコ免疫不全ウイルス / マウスエイズ / シグナル伝達 / 疾患モデル / ガラクトース転移酵素 / セレクチン / 初期胚 / 炎症 / 感染免疫 / 感染防御 / 獲得免疫 / 炎症反応 / C型レクチン受容体 / C-type lectin / 遺伝子改変動物 / 卵成熟 / アクロシン / 単為発生 / キメラ胚 / 遺伝子発現 / 卵丘 / 減数分裂 / oocyte maturation / fertilization / acrosin / endothelin / parthenogenesis / chimeras / バベシア原虫 / トキソプラズマ原虫 / Toxoplasma / 発生工学 / STAT5 / アポトーシス / IL-3 / コンタクチン / IL-1 / 関節リウマチ / Inflammation / TAG-1 / SDF-1 / B-1細胞 / HIV / LTR / トキソプラズマ / インターフェロンガンマ / interferon gamma / MyD88 / NO / 自己免疫疾患 / 自然免疫受容体 / HTLVーI taxー1遺伝子 / HIVーtatIII遺伝子 / cーfos / vーmos / 家族性アミロイドポリニューロパチー / アンチセンス / 遺伝子標的導入法 / 共培養 / 成長ホルモン遺伝子 / インターフェロン遺伝子 / 家族性アミロイドニュ-ロパシ- / 高血圧症モデル / ジ-ンタ-ゲッティング法 / キメラ / テラト-マ / サル / ウシ / 分化遺伝子 / モデル動物 / ジ-ンタ-ゲッティング / 標的遺伝子置換法 / 高血圧 / 高脂血症 / 始原生植細胞 / 胚奇形腫 / 遺伝子導入動物 / 核移植 / 相同的組替え / 癌抑制院伝子 / 単一遺伝子病 / 分子生物学 / 遺伝子単離 / 病因変異 / 遺伝子診断 / 遺伝子治療 / ジーンターゲッティング / 胚幹細胞 / 遺伝子欠損モデル / トランスサイレチン / HTLVI / 組換えウイルス / エイズ / 動物モデル / 癌抑制遺伝子 / キメラウイルス / スキッドマウス / ヒト免疫不全ウイルス / 後天性免疫不全症 / ヒト免疫不全ウィルス / サル免疫不全ウィルス / ネコ免疫不全ウィルス / チロシンキナーゼ / G-CSF受容体(G-CSFR) / Kostmann症候群 / 変異G-CSFR / 白血病 / MDS / 造血幹細胞 / 血球分化 / 糖鎖 / 絨毛性性腺刺激ホルモン / 胎盤性ラクトジェン / 白血病抑制因子 / cDNA突然変異誘発法 / 分子進化 / 成長遅延 / 胎生致死 / 遅延型接触過敏症反応 / 再生医学 / 発生・分化 / 遺伝子 / 神経幹細部 / 多能性 / Oct-3 / 4 / Nanog / 再プログラム化 / データベース / siRNA / 脂肪細胞 / インスリン / 肥満 / 腫瘍免疫 / T細胞 / Th17 / 疾患モデルマウス / ｻｲﾄｶｲﾝ / 真菌感染防御 / 細菌感染 / 骨代謝 / レクチン / Ｃ型レクチン受容体 / DCIR / リガンド / テラトカルシノーマ / 核移植細胞 / 細胞工学方法 / 腫瘍遺伝子 / HTLVー / pXーI遺伝子 / HTLVーII / pXーII遺伝子 / DNAートランスフェクション / ヒト成人性T細胞白血病 / 人小細胞肺癌 / 生殖系列 / HTLV-1 tax-1 / HIV-1 tatIII / TNF / 染色体外環状DNA / カニクイザル / 体外培養 / 胚割球の分離 / 胚の分化と増殖 / F9細胞 / グロビン / チミヂンキナーゼ遺伝子 / サイクリン / エンドセリン / アデノウイルスベクター / 性分化 / 性判別 / レポーター遺伝子 / 顕微注入 / メタロチオネイン / ベータガラクトシダーゼ / cyclin / adenovirus / 遺伝子ターゲット / c-mos 遺伝子 / 胚の凍結保存 / 遺伝子ターゲット法 / c-mos遺伝子 / 初期発生 / 性比 / PCR / c-mos / embryo freezing / ジーンターゲティング / 生殖 / 初期胚操作 / 胚分化 / 着床 / 性腺 / トランスジェニック動物 / Transgenic animal / Gene targetting / Reproduction / Embryo manipulation / Embryo differentiation / Fertilization / Implantation / Gonad / マクロファージ / スカベンジャー受容体 / インターフェロン / トリパノソーマ原虫 / 遺伝子導入 / インターフエロン / ネオスポーラ原虫 / Transgenic / macrophage / Scavenger receptor / Interferon / Babesia / Trypanosoma / mouse / サイトカインノックアウトマウス / 防御免疫 / リコンビナント抗原 / 診断用抗原 / モノクローナル抗体 / マウスバベシア / ウマバベシア / イヌバベシア / ELISA / 防御抗原 / Babesia parasites / protective immunity / cytokine knock-out mice / recombinant antigen / gene engineering / diagnostic antigens / Monoclonal antibody / developmental engineering / サイトカインセプター / 転写因子 / 分化 / 増殖 / サイトカインレセプター / Cytokine / Cytokine receptor / Transcription factor / Apotosis / Differentiation / Proliferation / 接着分子 / 神経細胞 / プロテアーゼ阻害剤 / CCR5阻害剤 / 薬剤耐性 / CXCR4阻害剤 / 膜融合阻害剤 / Vprトランスジェニックマウス / 中和抗体 / 逆転写酵素阻害剤 / HIV-1 / T140 / CXCR4拮抗剤 / 遺伝子発現制御 / hu-PBL-SCIDマウス / ケモカインレセプター阻害剤 / 発症予防ワクチン / 抗ウイルス剤 / CTL / tat / 転写制御 / フィットネス / rev / u-CRM1 / Protease inhibitor / CCR5 inhibitor / Drug resistance / CXCR4 inhibitor / Membrane fusion inhibitor / Vpr transgenic mouse / Neutralizing antibody / Reverse transcriptase inhibitor / 抗体産生 / 接触過敏症反応 / ストレス応答 / T細胞フライミング / 細菌誘導性肝炎 / ディファレンシャル・ディスプレイ / エンドトキシンショック / Knockout mice / Antibody Production / Contact Hypersensitivity / RheumatoidArthritis / Stress Response / Apoptosis / 細胞接着分子 / 脳神経細胞 / 免疫グロブリンスーパーファミリー / アデノシン / Gene targeting / Knockout mouse / axon guidance / Adenosine / コンタクチンサブグループ / 神経接着分子 / NB-3欠損マウス / 行動実験 / 運動機能障害 / LacZ遺伝子 / 発現 / NB-3 / 遺伝子変異マウス / contakutin subgroup / cell adhesion molecule / NB-3 deficient mice / behavior / motor coordination / Lac Z gene / expression / ケモカイン / 血液幹細胞 / transgenic mice / stem cell / scid mice / cDNAマイクロアレイ / トキソプラズマ原虫ストレス蛋白HSP70 / T.g.HSP70遺伝子 / T.g.HSP30遺伝子 / SAG1遺伝子 / IFN-γKOマウス / HSP70自己抗体 / RAG遺伝子 / testesterone / TgHSP70遺伝子 / TgHSP30遺伝子 / マイクロアレー / IFN-γ / danger signal / Toxoplasma gondi / cDNA microarray / T.gondii stress protein HSP70 / T.g.HSP70 / T.g.HSP30 / SAG1 / IFN-γ knockout (KO) mice / VTR / 転写 / CpGメチル化 / 潜状感染 / 転写抑制 / 潜伏感染 / Histone Code / クロマチン免疫沈降法 / ヌクレオソーム / 潜伏HIV再活性化シグナルによるLTRの脱メチル化制御 / 細胞内シグナル伝達 / Transcription / CpG Methylation / Latent Infection / 網脈絡膜炎 / 熱ショック蛋白 / 臓器特異性 / インターフェロンガンマノックアウトマウス / chorioretinitis / heat shock protein / organ specificity / interferon gamma knock out mouse / 骨破壊 / 破骨細胞 / 破骨細胞分化因子 / 破骨細胞形成抑制因子 / BONE DESTRUCTION / OSTEOCLASTS / OSTEOCLAST DIFFERENTIATION FACTOR / OSTEOCLASTOGENESIS INHIBITORY FACTOR / TRANSGENIC MICE / ノックアウト / Embryonic Srem cell / Knockout / Genetic altered animals / トキソプラズマ件網脈絡膜炎 / マイクロアレイ / ブドウ膜炎 / 網膜血管炎 / トキソプラズマ性網脈絡膜炎 / toxoplasmic retinochoroiditis / micro array / uveitis / retinal vasculitis / トキソプラズマ由来ストレス蛋白TgHSP70 / Toll-like receptor / NO産生 / 全身性エリテマトーデス / トキソプラズマ毒性分子 / TgHSP70 / 自然免疫と獲得免疫 / B-1エフェクター細胞 / 全身性エリトマトーデス / B-2抑制性細胞 / ループス腎炎 / TLR2 / TLR4 / IRAK4 / 抑制性B-2細胞 / T.gondii-derived HSP70(TgHSP70) / Toll like receptor(TLR) / systemic erthetodes / innate immunity / acquired immunity / B-1 effector cells / 自己免疫 / 疾患モデル動物 / 炎症性疾患 / 網羅的解析 / Animal disease models / cytokine / Rheumatoid arthritis / Dendritic cells / Autoimmune / Innate immunity / 免疫シグナル伝達 / DAMP / HMGB1 / 炎症・がん / 恒常性維持 / がん / 免疫原性核酸 / CRISPR-Cas Less

Analysis of inflammation, allergy, fibrosis, and tumorigenesis through the innate immune systemPrincipal InvestigatorOngoing
- Principal Investigator
  
  岩倉洋一郎
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Tokyo University of Science
Generation of gene-modified mice by targeting on innate immune receptor family and analysis of the function of these receptors by using human disease-models.Ongoing
- Principal Investigator
  
  唐策
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  Tokyo University of Science
真菌感染現象における抑制型C型レクチン受容体の生理機能の解明Ongoing
- Principal Investigator
  
  矢部力朗
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  Chiba University
自然免疫受容体を介した腸管免疫の制御と全身免疫への影響の解析Principal InvestigatorOngoing
- Principal Investigator
  
  岩倉洋一郎
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  Tokyo University of Science
C型レクチン受容体の生理機能の解析と疾病制御への応用Principal InvestigatorOngoing
- Principal Investigator
  
  岩倉洋一郎
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Tokyo University of Science
Elucidation of the host's homeostatic responses by the regulation of immune system and its application to the prevention and treatment of immunological disordersOngoing
- Principal Investigator
  
  谷口維紹
- Project Period (FY)
  2015 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Immunology
- Research Institution
  The University of Tokyo
Anti-fungal Immunity
- Principal Investigator
  
  Saijo Shinobu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bacteriology (including mycology)
- Research Institution
  Chiba University
The physiological functions of a C-type lectin receptor and the relation with diseases
- Principal Investigator
  
  KAIFU Tomonori
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  Tohoku Medical and Pharmaceutical University
  Tokyo University of Science
Establishment of an IL-1-related gene-manipulated mouse library and dissection of the gene-targeted mice, aiming at identifying new therapeutic targets for diseasesPrincipal Investigator
- Principal Investigator
  
  Iwakura Yoichiro
- Project Period (FY)
  2012 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Laboratory animal science
- Research Institution
  Tokyo University of Science
創薬標的の探索を目指したIL-1関連遺伝子改変マウスライブラリーの作製研究Principal Investigator
- Principal Investigator
  
  岩倉洋一郎
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Laboratory animal science
- Research Institution
  Tokyo University of Science
The role of C-type lectins in the host defense against fungal infections
- Principal Investigator
  
  SAIJO Shinobu
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Chiba University
Establishing a new animal model for ankylosing spondylolysis using DCIR deficient mice
- Principal Investigator
  
  KAIFU Tomonori
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  Tokyo University of Science
  The University of Tokyo
真菌感染防御におけるC型レクチンの役割
- Principal Investigator
  
  西城忍
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Chiba University
  The University of Tokyo
炎症性サイトカインとC型レクチンによる発がん制御機構の解析
- Principal Investigator
  
  角田茂
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Establishment of an IL-1-related gene-manipulated mice library, aiming at uncovering pathophysiology of disease from a view point of systems biologyPrincipal Investigator
- Principal Investigator
  
  IWAKURA Yoichiro
- Project Period (FY)
  2008 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Laboratory animal science
- Research Institution
  The University of Tokyo
疾患のシステム的理解を目指したIL-1関連遺伝子欠損マウスライブラリーの作製Principal Investigator
- Principal Investigator
  
  岩倉洋一郎
- Project Period (FY)
  2008
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Laboratory animal science
- Research Institution
  The University of Tokyo
インターロイキン17/17Fによる細菌感染防御機構の解析Principal Investigator
- Principal Investigator
  
  岩倉洋一郎
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
The roles of cytokines in the development of autoimmune deseasesPrincipal Investigator
- Principal Investigator
  
  IWAKURA Yoichiro
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
骨・軟骨の恒常性維持におけるケモカイン及びC型レクチンの役割の解明Principal Investigator
- Principal Investigator
  
  岩倉洋一郎
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
脂肪細胞から分泌されるlL-1Raの役割
- Principal Investigator
  
  千田大
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
自己免疫性関節炎発症における樹状細胞の役割Principal Investigator
- Principal Investigator
  
  岩倉洋一郎
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Roles of dendritic cells in the development of autoimmune arthropathyPrincipal Investigator
- Principal Investigator
  
  IWAKURA Yoichiro
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  The University of Tokyo
Analysis of genes involved in the pathogenesis of the arthritis using animal disease models..
- Principal Investigator
  
  SAIJO Shinobu
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  The University of Tokyo
関節リウマチの遺伝的要因の解析Principal Investigator
- Principal Investigator
  
  岩倉洋一郎
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
自己免疫性関節炎発症における樹状細胞の役割Principal Investigator
- Principal Investigator
  
  岩倉洋一郎
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
慢性関節リウマチの遺伝的要因の解析Principal Investigator
- Principal Investigator
  
  岩倉洋一郎
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
HTLV-Iによる自己免疫性慢性関節炎発症機構の解明Principal Investigator
- Principal Investigator
  
  岩倉洋一郎
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
体細胞初期化誘導および未分化維持に関するシグナル因子の解析
- Principal Investigator
  
  角田茂, 須藤カツ子
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Interplay between TLR-mediated innate immunity, acquired immunity and in Toxoplasma gondii-derived heat shock protein, TgHSP70, in toxoplasmosis
- Principal Investigator
  
  YANO Akihiko
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Parasitology (including Sanitary zoology)
- Research Institution
  Chiba University
疾患モデルマウスを用いた関節リウマチの遺伝的要因の解析Principal Investigator
- Principal Investigator
  
  岩倉洋一郎
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
HTLV-Iによる自己免疫性慢性関節炎発症機構の解明Principal Investigator
- Principal Investigator
  
  岩倉洋一郎
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
cDNA microarray analysis of toxoplasmic retinochoroiditis
- Principal Investigator
  
  NOROSE Kazumi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Chiba University
IL-1による免疫応答制御機構の解明Principal Investigator
- Principal Investigator
  
  岩倉洋一郎
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
関節リウマチの遺伝要因の解明Principal Investigator
- Principal Investigator
  
  岩倉洋一郎
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
インターフェロン・サイトカインの抗癌作用の研究Principal Investigator
- Principal Investigator
  
  岩倉洋一郎
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
HTLV-Iによる自己免疫性慢性関節炎発症機構の解明Principal Investigator
- Principal Investigator
  
  岩倉洋一郎
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
A STUDY ON THE CONTROL OF BONE DESTRUCTION USING OSTEOCLAST DIFFERENTIATION FACTOR AS A TARGET
- Principal Investigator
  
  YASUDA Hisataka
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  THE UNIVERSITY OF TOKYO
Establishment of ES cell lines derived from several inbred strains
- Principal Investigator
  
  SUDO Katsuko
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  The University of Tokyo
IL-1による免疫応答制御機構の解明Principal Investigator
- Principal Investigator
  
  岩倉洋一郎
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
関節リウマチの遺伝要因の解明Principal Investigator
- Principal Investigator
  
  岩倉洋一郎
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
インターフェロン・サイトカインの抗癌作用の研究Principal Investigator
- Principal Investigator
  
  岩倉洋一郎
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
The roles of cytokines on the development of rheumatoid arthritisPrincipal Investigator
- Principal Investigator
  
  IWAKURA Yoichiro
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  The University of Tokyo
Establishment of in-house cDNA microarray for analysis of pathogenicity of Toxoplasma gondii infection and developing methods of diagnosis and therapy for toxoplasmosis
- Principal Investigator
  
  YANO Akihiko
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  寄生虫学(含医用動物学)
- Research Institution
  Chiba University
Regulation Mechanisms of HIV LTR Demethylation through Reactivation Signaling
- Principal Investigator
  
  ISHIDA Takaomi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  The University of Tokyo
Effect of Heart Shock Protein and Interferon on Toxoplasmic Chorioretinitis
- Principal Investigator
  
  NOROSE Kazumi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  CHIBA UNIVERSITY
インターフェロン・サイトカインの抗癌作用の研究Principal Investigator
- Principal Investigator
  
  岩倉洋一郎
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  The University of Tokyo
ヒトT細胞白血病ウイルスによる自己免疫発症機構の解析Principal Investigator
- Principal Investigator
  
  岩倉洋一郎
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  The University of Tokyo
ガラクトース転移酵素遺伝子ノックアウトマウスを用いた糖鎖機能の解析
- Principal Investigator
  
  浅野雅秀
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kanazawa University
発生工学的手法によるエイズ制圧の試みPrincipal Investigator
- Principal Investigator
  
  岩倉洋一郎
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
発生工学的手法を用いたケモカインによる造血分化決定機構の解析Principal Investigator
- Principal Investigator
  
  岩倉洋一郎
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Production and Analysis of TAG-1 Knockout Mouse
- Principal Investigator
  
  FUKAMAUCHI Fumihiko
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neuroscience in general
- Research Institution
  Tokyo Medical and Dental University
Generation and analysis of NB-3 deficient mice
- Principal Investigator
  
  WATANABE Kazutada
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neuroscience in general
- Research Institution
  Tokyo Metropolitan Institute of Gerontology
A trial to generate recipient mice which support the development of human hematopoietic stem cells to T-lymphocytes
- Principal Investigator
  
  SUDO Katsuko
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  The University of Tokyo
ヒトT細胞白血病ウイルスによる自己免疫発症機構の解析Principal Investigator
- Principal Investigator
  
  岩倉洋一郎
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  The University of Tokyo
ガラクトース転移酵素遺伝子ノックアウトマウスを用いた糖鎖機能の解析
- Principal Investigator
  
  浅野雅秀
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  The University of Tokyo
発生工学的手法によるエイズ制圧の試みPrincipal Investigator
- Principal Investigator
  
  岩倉洋一郎
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Basic Research for AIDS control A03 ; Prevention and control of AIDS
- Principal Investigator
  
  MATSUSHITA Shuzo
- Project Period (FY)
  1998 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  KUMAMOTO UNIVERSITY
Development of rheumatoid arthritis models using transgenic techniquePrincipal Investigator
- Principal Investigator
  
  IWAKURA Yoichiro
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Laboratory animal science
- Research Institution
  The University of Tokyo
Functional analysis of IL-1 in immune and stress responses using gene knockout mice
- Principal Investigator
  
  ASANO Masahide
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Kanazawa University
  The University of Tokyo
インターフェロンによるアポトーシスの誘導と発がん抑制Principal Investigator
- Principal Investigator
  
  岩倉洋一郎
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
ヒトG-CSFレセプタートランスジェニックマウスを用いた白血病発症機構の研究
- Principal Investigator
  
  中畑龍俊
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
ヒト細胞白血病ウィルスによる自己免疫症機構の解析Principal Investigator
- Principal Investigator
  
  岩倉洋一郎
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
糖鎖による情報積載の分子発達：糖タンパク質の機能と構造
- Principal Investigator
  
  小川智也
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Basic veterinary science/Basic zootechnical science
- Research Institution
  The University of Tokyo
Analysis on protective antigen of Babesia parasites by developmental engineering
- Principal Investigator
  
  IGARASHI Ikuo
- Project Period (FY)
  1997 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Applied veterinary science
- Research Institution
  Obihiro University Agriculture and Veterinary Medicine
Activation of cytokine signaling by constitutively active STAT5.
- Principal Investigator
  
  KITAMURA Toshio
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  The University of Tokyo
ジーンターゲティングによるコンタクチン遺伝子欠損マウスの作製と解析
- Principal Investigator
  
  FUKAMAUCHI Fumihiko
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neuroscience in general
- Research Institution
  Tokyo Medical and Dental University
標的遺伝子組み換え法によるサイトカインの炎症反応における役割の解析Principal Investigator
- Principal Investigator
  
  岩倉洋一郎
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
ヒトT細胞白血病ウイルスによる自己免疫発症機構の解析Principal Investigator
- Principal Investigator
  
  岩倉洋一郎
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
Deveropmental biotechnological analysis of host defense mechanisms against protozoan infection
- Principal Investigator
  
  TOYODA Yutaka
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Applied veterinary science
- Research Institution
  OBIHIRO UNIVERSITY OF AGRICULTURE AND VETERINARY MEDICINE
サイトカイン研究のための遺伝子改変マウスライブラリーの作製Principal Investigator
- Principal Investigator
  
  岩倉洋一郎
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Laboratory animal science
- Research Institution
  The University of Tokyo
標的遺伝子組み換え法を用いたサイトカインの生理機能の解析Principal Investigator
- Principal Investigator
  
  岩倉洋一郎
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
エイズの病態と制御に関する基礎研究エイズの動物モデル
- Principal Investigator
  
  速水正憲
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
遺伝子導入マウスのコンピューターによる維持・管理システムの開発Principal Investigator
- Principal Investigator
  
  岩倉洋一郎
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  The University of Tokyo
単一遺伝子病の分子・細胞生物学的研究
- Principal Investigator
  
  多田啓也, 勝木元也
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
  Kyushu University
エイズ制圧に向けての基礎研究・エイズの動物モデル
- Principal Investigator
  
  速水正憲
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
標的遺伝子組換え法を用いたサイトカインの生理機能の解析Principal Investigator
- Principal Investigator
  
  岩倉洋一郎
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
遺伝子導入動物による発癌の研究
- Principal Investigator
  
  樋野興夫
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Japanese Foundation For Cancer Research
遺伝子導入動物による発症の研究
- Principal Investigator
  
  山村研一
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kumamoto University
トランスジェニックマウスを用いたインターフェロンの癌抑制作用の解析Principal Investigator
- Principal Investigator
  
  岩倉洋一郎
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
成人T細胞白血病ウイルスによる自己免疫状態の誘導機構に関する研究Principal Investigator
- Principal Investigator
  
  岩倉洋一郎
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
標的遺伝子組換え法を用いたサイトカインの生理機能の解析Principal Investigator
- Principal Investigator
  
  岩倉洋一郎
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
Biotechnological studies on the mechanisms regulating embryogenesis
- Principal Investigator
  
  TOYODA Yutaka
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  Applied animal science
- Research Institution
  The University of Tokyo
Analysis of reproductive processes by means of transgenic animals
- Principal Investigator
  
  TAKAHASHI Michio
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  Basic veterinary science/Basic zootechnical science
- Research Institution
  The University of Tokyo
遺伝子導入動物による発癌の研究
- Principal Investigator
  
  山村研一
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kumamoto University
遺伝子破壊法によるインターフェロンの癌抑制機能の解析Principal Investigator
- Principal Investigator
  
  岩倉洋一郎
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
Studies on te regulatory mechanisms of gene expression in early embryos
- Principal Investigator
  
  TOYODA Yutaka
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  畜産学(含草地学)
- Research Institution
  The University of Tokyo
Pathogenesis of inflammatory arthropathy developed in HTLV-I transgenic micePrincipal Investigator
- Principal Investigator
  
  IWAKURA Yoichiro
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  The University of Tokyo
遺伝子導入動物による発癌の研究
- Principal Investigator
  
  山村研一
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kumamoto University
外来遺伝子DNA導入による新しいモデル動物の開発
- Principal Investigator
  
  勝木元也
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
初期発生における割球分化の分子機構
- Principal Investigator
  
  入谷明
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
初期発生における割球分化の分子機構
- Principal Investigator
  
  入谷明
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
発癌遺伝子移入による正常造血系細胞のimmortalization
- Principal Investigator
  
  関口豊三
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kohno Clinical Medicine Research Institute
初期発生の分子機構
- Principal Investigator
  
  入谷明
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
発癌遺伝子移入による正常造血系細胞のimmortalzation
- Principal Investigator
  
  関口豊三
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kohno Clinical Medicine Research Institute
個体レベルにおける各種インターフェロンの生物活性の検討Principal Investigator
- Principal Investigator
  
  岩倉洋一郎
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  The University of Tokyo
初期発生の分子機構
- Principal Investigator
  
  入谷明
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
外来遺伝子DNA導入による新しいモデル動物の開発
- Principal Investigator
  
  勝木元也
- Project Period (FY)
  1987 – 1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokai University
外来遺伝子DNA導入による新しいモデル動物の開発
- Principal Investigator
  
  勝木元也
- Project Period (FY)
  1987 – 1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokai University
発癌遺伝子の移入による正常造血系細胞のImmortalizationと癌化
- Principal Investigator
  
  関口豊三
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
生殖系列の分子機構に関する基礎研究
- Principal Investigator
  
  毛利秀雄
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Institution
  The University of Tokyo
細胞工学方法によるテラトカルシノーマの分化誘導と腫瘍遺伝子発現の制御
- Principal Investigator
  
  関口豊三
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East

[Book] トピックス「自己免疫疾患に対する新たな治療標的の発見」2017
- Author(s)
  村山正承、岩倉洋一郎
- Total Pages
  4
- Publisher
  理大科学フォーラム
- Data Source
  KAKENHI-PROJECT-24220011
[Book] トピックス「自己免疫疾患に対する新たな治療標的の発見」2017
- Author(s)
  村山正承、岩倉洋一郎
- Total Pages
  4
- Publisher
  理大科学フォーラム
- Data Source
  KAKENHI-PROJECT-15H05787
[Book] セミナー室「低分子βグルカン摂取により炎症性腸疾患を予防，改善する」2016
- Author(s)
  唐策、角田茂、岩倉洋一郎
- Total Pages
  6
- Publisher
  日本農芸化学会
- Data Source
  KAKENHI-PROJECT-24220011
[Book] 医歯薬出版株式会社2016
- Author(s)
  秋津葵、岩倉洋一郎
- Total Pages
  5
- Publisher
  自己免疫性関節炎と病原性T細胞
- Data Source
  KAKENHI-PROJECT-24220011
[Book] 自己免疫性関節炎と病原性T細胞2016
- Author(s)
  秋津葵、岩倉洋一郎
- Total Pages
  5
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-15H05787
[Book] Dendritic Cell Immunoreceptor (DCIR): An ITIM-Harboring C-Type Lectin Receptor.2016
- Author(s)
  Tomonori Kaifu and Yoichiro Iwakura.
- Total Pages
  12
- Publisher
  Springer Japan
- Data Source
  KAKENHI-PROJECT-15H05787
[Book] IL－1ファミリー分子による免疫制御2016
- Author(s)
  秋津葵、岩倉洋一郎
- Total Pages
  7
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-24220011
[Book] セミナー室「低分子βグルカン摂取により炎症性腸疾患を予防，改善する」2016
- Author(s)
  唐策、角田茂、岩倉洋一郎
- Total Pages
  6
- Publisher
  日本農芸化学会
- Data Source
  KAKENHI-PROJECT-15H05787
[Book] Dendritic Cell Immunoreceptor (DCIR): An ITIM-Harboring C-Type Lectin Receptor.2016
- Author(s)
  Tomonori Kaifu and Yoichiro Iwakura.
- Total Pages
  12
- Publisher
  Springer Japan
- Data Source
  KAKENHI-PROJECT-24220011
[Book] IL-1ファミリー分子による免疫制御2016
- Author(s)
  秋津葵、岩倉洋一郎
- Total Pages
  7
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-15H05787
[Book] 第1章インターロイキン「IL-10」サイトカイン・増殖因子キーワード事典2015
- Author(s)
  鄭琇絢、岩倉洋一郎
- Total Pages
  3
- Publisher
  洋土社
- Data Source
  KAKENHI-PROJECT-24220011
[Book] 第1章インターロイキン「成長ホルモン」「プロラクチン」サイトカイン・増殖因子キーワード事典2015
- Author(s)
  米沢朋、丸田大貴、岩倉洋一郎
- Total Pages
  5
- Publisher
  洋土社
- Data Source
  KAKENHI-PROJECT-24220011
[Book] 【大学発日本人と技術】日本を支える研究活動と技術開発関節リウマチの新たな治療薬開発2015
- Author(s)
  村山正承、岩倉洋一郎
- Total Pages
  1
- Publisher
  フジサンケイビジネスアイ
- Data Source
  KAKENHI-PROJECT-24220011
[Book] 第1章インターロイキン「IL-14」「IL-16」「IL-32」サイトカイン・増殖因子キーワード事典2015
- Author(s)
  村山正承、岩倉洋一郎
- Total Pages
  3
- Publisher
  洋土社
- Data Source
  KAKENHI-PROJECT-24220011
[Book] 第2章インターフェロン「概論」「IFN-α/β」「IFN-γ」「IFN-λファミリー（IL-28, IL-29）」サイトカイン・増殖因子キーワード事典2015
- Author(s)
  角田茂、岩倉洋一郎
- Total Pages
  10
- Publisher
  洋土社
- Data Source
  KAKENHI-PROJECT-24220011
[Book] 第1章インターロイキン「IL-19/20/22/24/26」サイトカイン・増殖因子キーワード事典2015
- Author(s)
  神谷知憲、岩倉洋一郎
- Total Pages
  3
- Publisher
  洋土社
- Data Source
  KAKENHI-PROJECT-24220011
[Book] Current Topics. デクチン1シグナルの阻害は、腸内乳酸桿菌を増殖させ、制御性Ｔ細胞を増加させることによって、大腸炎を抑制する」実験医学20162015
- Author(s)
  唐策、岩倉洋一郎
- Total Pages
  4
- Publisher
  洋土社
- Data Source
  KAKENHI-PROJECT-24220011
[Book] 第1章インターロイキン「IL-23/35」サイトカイン・増殖因子キーワード事典2015
- Author(s)
  唐策、岩倉洋一郎
- Total Pages
  3
- Publisher
  洋土社
- Data Source
  KAKENHI-PROJECT-24220011
[Book] 第1章インターロイキン「IL-18/33/36/37」サイトカイン・増殖因子キーワード事典2015
- Author(s)
  海部知則、岩倉洋一郎
- Total Pages
  3
- Publisher
  洋土社
- Data Source
  KAKENHI-PROJECT-24220011
[Book] 第1章インターロイキン「IL-17A/17B/17C/17D/17E/17F」サイトカイン・増殖因子キーワード事典2015
- Author(s)
  秋津葵、岩倉洋一郎
- Total Pages
  3
- Publisher
  洋土社
- Data Source
  KAKENHI-PROJECT-24220011
[Book] 第1章インターロイキン「IL-12」サイトカイン・増殖因子キーワード事典2015
- Author(s)
  矢部力朗、岩倉洋一郎
- Total Pages
  2
- Publisher
  洋土社
- Data Source
  KAKENHI-PROJECT-24220011
[Book] 第1章インターロイキン「IL-1」サイトカイン・増殖因子キーワード事典2015
- Author(s)
  清水謙次、岩倉洋一郎
- Total Pages
  3
- Publisher
  洋土社
- Data Source
  KAKENHI-PROJECT-24220011
[Book] 実験医学増刊、炎症―全体像を知り慢性炎症を制御するー2014
- Author(s)
  矢部力朗、岩倉洋一郎、西城忍
- Total Pages
  219
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-24220011
[Book] サイトカインと自己免疫疾患．EXPERT膠原病・リウマチ　改訂第３版（住田孝之編）2013
- Author(s)
  角田茂、岩倉洋一郎
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-24220011
[Book] 遺伝子改変動物.新しい薬学事典2012
- Author(s)
  角田茂、岩倉洋一郎
- Publisher
  朝倉書店(印刷中)
- Data Source
  KAKENHI-PROJECT-20220009
[Book] 炎症性サイトカインと骨破壊2012
- Author(s)
  海部知則, 岩倉洋一郎
- Publisher
  医学のあゆみ
- Data Source
  KAKENHI-PROJECT-23500489
[Book] 発刊にあたって.免疫疾患-疾患モデルの作製と利用.シリーズモデル動物利用マニュアル2011
- Author(s)
  岩倉洋一郎
- Total Pages
  580
- Publisher
  エル・アイ・シー
- Data Source
  KAKENHI-PROJECT-20220009
[Book] IL-1. seriesモデル動物利用マニュアル免疫疾患-疾患モデルの作製と利用2011
- Author(s)
  角田茂、岩倉洋一郎
- Publisher
  エル・アイ・シー
- Data Source
  KAKENHI-PROJECT-20220009
[Book] 遺伝子改変マウス."哺乳動物の分子生物学"を切り拓いた技術バイオテクノロジーの温故知新2011
- Author(s)
  岩倉洋一郎
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-20220009
[Book] 免疫疾患.疾患モデルの作製と利用.シリーズ「モデル動物利用マニュアル」2011
- Author(s)
  岩倉洋一郎
- Total Pages
  580
- Publisher
  エル・アイ・シー
- Data Source
  KAKENHI-PROJECT-20220009
[Book] アグリゲーション法によるキメラマウスの作製.改訂第5版新遺伝子工学ハンドブック2010
- Author(s)
  角田茂、佐藤希、久保幸子、岩倉洋一郎
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-20220009
[Book] Dcirと自己免疫疾患最新医学2009
- Author(s)
  藤門範行、岩倉洋一郎
- Data Source
  KAKENHI-PROJECT-20220009
[Book] サイトカインシグナルと代謝疾患2008
- Author(s)
  千田大、岩倉洋一郎
- Publisher
  ニュー・サイエンス社
- Data Source
  KAKENHI-PROJECT-20220009
[Book] nterleukin-1 deficiency and aggressiveness in male mice.(M.T. Czerbnska ed., Psychoneuroendocrinology Research Trends)2007
- Author(s)
  Tamagawa, A., Kolosova, I., Endo, Y., Gerlinskaya, L., Iwakura, Y., Moshikin, M.
- Publisher
  Nova Science Publishers, Inc.
- Data Source
  KAKENHI-PROJECT-19059006
[Book] The roles of IL-17A and IL-17F in mucosal infection and allergy.(ed. S. Jiang, Th17 cells in health and disease)
- Author(s)
  Ishigame, H., Nakae, S., Iwakura, Y.
- Publisher
  Springer Science + Buisiness(in press)
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] IL-1β Plays an Important Role in Pressure Overload-Induced Atrial Fibrillation in Mice2019
- Author(s)
  Matsushita Naoko、Ishida Nanae、Ibi Miho、Saito Maki、Takahashi Masafumi、Taniguchi Shunichiro、Iwakura Yoichiro、Morino Yoshihiro、Taira Eiichi、Sawa Yohei、Hirose Masamichi
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume: 42 Issue: 4 Pages: 543-546
- DOI
  10.1248/bpb.b18-00363
- NAID
  130007622152
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08112, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-15H05787
[Journal Article] Epidermal loss of phospholipase Cδ1 attenuates irritant contact dermatitis2019
- Author(s)
  Shiratori Kanako、Kanemaru Kaori、Ogura Takahiro、Nakajima Aya、Sugizaki Yuko、Fukuyama Takatsugu、Iwakura Yoichiro、Nakamura Yoshikazu、Fukami Kiyoko
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 511 Pages: 330-335
- DOI
  10.1016/j.bbrc.2019.02.046
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-18H02575
[Journal Article] Dectin-2?Mediated Signaling Leads to Delayed Skin Wound Healing through Enhanced Neutrophilic Inflammatory Response and Neutrophil Extracellular Trap Formation2019
- Author(s)
  Miura T, Kawakami K, Tada H (5番目), Tachi M. (員数19).
- Journal Title
  
  The Journal of investigative dermatology
  
  Volume: 139(3) Pages: 702-711
- DOI
  10.1016/j.jid.2018.10.015
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11824, KAKENHI-PROJECT-18K09473, KAKENHI-PROJECT-18K19437, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-18H02671, KAKENHI-PROJECT-16K11909, KAKENHI-PROJECT-17K19710, KAKENHI-PROJECT-17K17393
[Journal Article] Dectin-1 Contributes to Myocardial Ischemia/Reperfusion Injury by Regulating Macrophage Polarization and Neutrophil Infiltration.2019
- Author(s)
  Fan Qin、Tao Rong、Zhang Hang、Xie Hongyang、Lu Lin、Wang Ting、Su Min、Hu Jian、Zhang Qi、Chen Qiujing、Iwakura Yoichiro、Shen Weifeng、Zhang Ruiyan、Yan Xiaoxiang
- Journal Title
  
  Circulation
  
  Volume: 139 Pages: 663-678
- DOI
  10.1161/circulationaha.118.036044
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-18H02671
[Journal Article] Role of interleukin-17 in a murine community-associated methicillin-resistant Staphylococcus aureus pneumonia model.2019
- Author(s)
  Shibue Yasushi、Kimura Soichiro、Kajiwara Chiaki、Iwakura Yoichiro、Yamaguchi Keizo、Tateda Kazuhiro
- Journal Title
  
  Microbes and infection
  
  Volume: 21 Pages: 33-39
- DOI
  10.1016/j.micinf.2018.06.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-18H02671
[Journal Article] A dendritic cell-based systemic vaccine induces long-lived lung-resident memory Th17 cells and ameliorates pulmonary mycosis.2019
- Author(s)
  Ueno Keigo、Urai Makoto、Sadamoto Sota、Shinozaki Minoru、Takatsuka Shogo、Abe Masahiro、Otani Yoshiko、Yanagihara Nao、Shimizu Kiminori、Iwakura Yoichiro、Shibuya Kazutoshi、Miyazaki Yoshitsugu、Kinjo Yuki
- Journal Title
  
  Mucosal immunology
  
  Volume: 12 Pages: 265-276
- DOI
  10.1038/s41385-018-0094-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K18385, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-16H05349, KAKENHI-PROJECT-18H02671
[Journal Article] IL-25 enhances Th17 cell-mediated contact dermatitis by promoting IL-1β production by dermal dendreitic cells.2018
- Author(s)
  Suto H, Nambu A, Morita H, Yamaguchi S, Numata T, Yoshizaki T, Shimura E, Arae K, Asada Y, Motomura K, Kaneko M, Abe T, Matsuda A, Iwakura Y, Okumura K, Saito H, Matsumoto K, Sudo K, Nakae S
- Journal Title
  
  J. Allergy Clin. Immunol
  
  Volume: In press Pages: 1500-1509
- DOI
  10.1016/j.jaci.2017.12.1007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04866, KAKENHI-PROJECT-16K20333, KAKENHI-PROJECT-18K08395, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-18H02671
[Journal Article] NK Cells Control Tumor-Promoting Function of Neutrophils in Mice.2018
- Author(s)
  Ogura K, Sato-Matsushita M, Yamamoto S, Hori T, Sasahara M, Iwakura Y, Saiki I, Tahara H, Hayakawa Y
- Journal Title
  
  Cancer immunology research
  
  Volume: 印刷中 Pages: 348-357
- DOI
  10.1158/2326-6066.cir-17-0204
- NAID
  120006402039
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-15K08902, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045
[Journal Article] IL-36α from Skin-Resident Cells Plays an Important Role in the Pathogenesis of Imiquimod-Induced Psoriasiform Dermatitis by Forming a Local Autoamplification Loop2018
- Author(s)
  Hashiguchi Y, Yabe R, Chung SH, Murayama MA, Yoshida K, Matsuo K, Kubo S, Saijo S, Nakamura Y, Matsue H, Iwakura Y.
- Journal Title
  
  Journal of immunology (Baltimore, Md. : 1950)
  
  Volume: 201 Pages: 167-182
- DOI
  10.4049/jimmunol.1701157
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19437, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-18H02671
[Journal Article] HER2 Overexpression Triggers an IL1-α Pro-inflammatory Circuit to Drive Tumorigenesis and Promote Chemotherapy Resistance.2018
- Author(s)
  Liu, S., Lee, J. S., Jie, C., Park, M. H., Iwakura, Y., Patel, Y., Soni, M., Reisman, D., and Chen, H.
- Journal Title
  
  Cancer research
  
  Volume: - Pages: 2040-2051
- DOI
  10.1158/0008-5472.can-17-2761
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05787, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045
[Journal Article] Apaf1 plays a negative regulatory role in T cell responses by suppressing activation of antigen-stimulated T cells2018
- Author(s)
  Tong, H., Miyake, Y., Mi-Ichi, F., Iwakura, Y., Hara, H. and Yoshida, H.
- Journal Title
  
  PloS one
  
  Volume: 13 Pages: 0195119-0195119
- DOI
  10.1371/journal.pone.0195119
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08888, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-16K08842, KAKENHI-PROJECT-16K19117, KAKENHI-PUBLICLY-16H01365
[Journal Article] Myeloid-derived interleukin-1β drives oncogenic KRAS-NF-NF-κB addiction in malignant pleural effusion.2018
- Author(s)
  Marazioti A, Lilis I, Vreka M, Apostolopoulou H, Kalogeropoulou A, Giopanou I, Giotopoulou GA, Krontira AC, Iliopoulou M, Kanellakis NI, Agalioti T, Giannou AD, Jones-Paris C, Iwakura Y, Kardamakis D, Blackwell TS, Taraviras S, Spella M, Stathopoulos GT.
- Journal Title
  
  Nature communications
  
  Volume: 9 Pages: 672-672
- DOI
  10.1038/s41467-018-03051-z
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045
[Journal Article] Production of low-molecular weight soluble yeast β-glucan by an acid degradation method.2018
- Author(s)
  Ishimoto Yuina、Ishibashi Ken-ichi、Yamanaka Daisuke、Adachi Yoshiyuki、Kanzaki Ken、Iwakura Yoichiro、Ohno Naohito
- Journal Title
  
  International journal of biological macromolecules
  
  Volume: 107 Pages: 2269-2278
- DOI
  10.1016/j.ijbiomac.2017.10.094
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-15H05787
[Journal Article] HER2 overexpression triggers an IL-1α pro-inflammatory circuit to drive tumorigenesis and promote chemotherapy resistance.2018
- Author(s)
  Liu, S., Lee, J. S., Jie, C., Park, M. H., Iwakura, Y., Patel, Y., Soni, M., Reisman, D., and Chen, H.
- Journal Title
  
  Cancer Res.
  
  Volume: 78 Pages: 2040-2051
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02671
[Journal Article] IL-1R2 deficiency suppresses dextran sodium sulfate-induced colitis in mice via regulation of microbiota2018
- Author(s)
  Yoshida, K., Murayama, M., Shimizu, K., Tang, C., Katagiri, N., Matsuo, K., Fukai F., and Iwakura, Y.
- Journal Title
  
  Biochemical and biophysical research communications
  
  Volume: 496 Pages: 934-940
- DOI
  10.1016/j.bbrc.2018.01.116
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05787, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045
[Journal Article] Increased mTOR cancels out the effect of reduced Xbp-1 on antibody secretion in IL-1α deficient B cells.2018
- Author(s)
  Zhu Gaizhi、Liu Xiaoling、Fang Ying、Zhai Bing、Xu Ruonan、Han Gencheng、Chen Guojiang、Xiao He、Hou Chunmei、Shen Beifen、Li Yan、Iwakura Yoichiro、Wang Liang、Jiang Zhenyu、Ma Ning、Liu Guangchao、Wang Renxi
- Journal Title
  
  Cellular immunology
  
  Volume: 328 Pages: 9-17
- DOI
  10.1016/j.cellimm.2018.02.015
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-15H05787
[Journal Article] MAIT cells protect against pulmonary Legionella longbeachae infection.2018
- Author(s)
  Wang H, D'Souza C, Lim XY, Kostenko L, Pediongco TJ, Eckle SBG, Meehan BS, Shi M, Wang N, Li S, Liu L, Mak JYW, Fairlie DP, Iwakura Y, Gunnersen JM, Stent AW, Godfrey DI, Rossjohn J, Westall GP, Kjer-Nielsen L, Strugnell RA, McCluskey J, Corbett AJ, Hinks TSC, Chen Z.
- Journal Title
  
  Nature communications
  
  Volume: 9 Pages: 3350-3350
- DOI
  10.1038/s41467-018-05202-8
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-18H02671
[Journal Article] BAFF inhibition attenuates fibrosis in scleroderma by modulating the regulatory and effector B cell balance.2018
- Author(s)
  Matsushita Takashi、Kobayashi Tadahiro、Mizumaki Kie、Kano Miyu、Sawada Tomoyo、Tennichi Momoko、Okamura Ai、Hamaguchi Yasuhito、Iwakura Yoichiro、Hasegawa Minoru、Fujimoto Manabu、Takehara Kazuhiko
- Journal Title
  
  Science advances
  
  Volume: 4 Pages: 9944-9944
- DOI
  10.1126/sciadv.aas9944
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-18H02671, KAKENHI-PROJECT-16K10147
[Journal Article] β-glucans in food modify colonic microflora by inducing antimicrobial protein, calprotectin, in a Dectin-1-induced-IL-17F-dependent manner.2018
- Author(s)
  Ishimoto, Y., Ishibashi, K. I., Yamanaka, D., Adachi, Y., Kanzaki, K., Iwakura, Y., and Ohno, N.
- Journal Title
  
  Mucosal Immunol
  
  Volume: 107 Pages: 2269-2278
- DOI
  10.1038/mi.2017.86
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05787, KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-18H02671
[Journal Article] A model of TH17-associated ileal hyperplasia that requires both IL-17A and IFN-γ to generate self-tolerance and prevent colitis.2018
- Author(s)
  Jeschke Jonathan C.、Mayne Christopher G.、Ziegelbauer Jennifer、DeCiantis Christopher L.、Singh Selina、Kumar Suresh N.、Suchi Mariko、Iwakura Yoichiro、Drobyski William R.、Salzman Nita H、Williams Calvin B.
- Journal Title
  
  Mucosal immunology
  
  Volume: 11 Pages: 1127-1137
- DOI
  10.1038/s41385-018-0023-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-18H02671
[Journal Article] Establishment and analysis of a novel mouse line carrying a conditional knockin allele of a cancer-specific FBXW7 mutation2018
- Author(s)
  Ikenoue T, Terakado Y, Zhu C, Liu X, Ohsugi T, Matsubara D, Fujii T, Kakuta S,Kubo S, Shibata T, Yamaguchi K, Iwakura Y, Furukawa Y.
- Journal Title
  
  Scientific reports
  
  Volume: 8 Pages: 2021-2021
- DOI
  10.1038/s41598-018-19769-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08672, KAKENHI-PROJECT-16K10558, KAKENHI-PROJECT-17K09369, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-26860227, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PUBLICLY-16H01569
[Journal Article] The ATP transporter VNUT mediates induction of Dectin-1-triggered Candida nociception.2018
- Author(s)
  Maruyama K, Takayama Y, Sugisawa E, Yamanoi Y, Yokawa T, Kondo T, Ishibashi KI, Sahoo BR, Takemura N, Mori Y, Kanemaru H, Kumagai Y, Martino MM, Yoshioka Y, Nishijo H, Tanaka H, Sasaki A, Ohno N, Iwakura Y, Moriyama Y, Nomura M, Akira S, Tominaga M.
- Journal Title
  
  iScience
  
  Volume: 6 Pages: 306-318
- DOI
  10.1016/j.isci.2018.08.007
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09885, KAKENHI-PROJECT-16K19148, KAKENHI-PROJECT-17K15793, KAKENHI-PLANNED-15H05928, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-16H01849, KAKENHI-PROJECT-18H01841, KAKENHI-PROJECT-18H02671, KAKENHI-PROJECT-18H02970, KAKENHI-PROJECT-17K15725
[Journal Article] Host defense against oral microbiota by bone-damaging T cells2018
- Author(s)
  Masayuki Tsukasaki, Noriko Komatsu, Kazuki Nagashima, Takeshi Nitta, Warunee Pluemsakunthai, Chisa Shukunami, Yoichiro Iwakura, Tomoki Nakashima, Kazuo Okamoto, and Hiroshi Takayanagi
- Journal Title
  
  Nat Commun
  
  Volume: 9 Pages: 701-701
- DOI
  10.1038/s41467-018-03147-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19582, KAKENHI-PROJECT-16H05202, KAKENHI-PROJECT-16H05506, KAKENHI-PROJECT-15H05653, KAKENHI-PROJECT-15F15414, KAKENHI-PROJECT-15J05324, KAKENHI-PROJECT-15H05703, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-16K15252, KAKENHI-PROJECT-26713015
[Journal Article] IL-36a is involved in hapten-specific T-cell induction, but not local inflammation, during contact hypersensitivity.2018
- Author(s)
  Numata Takafumi、Yoshizaki Takamichi、Yamaguchi Sachiko、Shimura Eri、Iwakura Yoichiro、Harada Kazutoshi、Sudo Katsuko、Tsuboi Ryoji、Nakae Susumu
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 506 Pages: 429-436
- DOI
  10.1016/j.bbrc.2018.10.104
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10256, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-18H02671, KAKENHI-PROJECT-18H02847
[Journal Article] Inhibition of interleukin-1 suppresses angiotensin II-induced aortic inflammation and aneurysm formation2018
- Author(s)
  Isoda K, Akita K, Kitamura K, Sato-Okabayashi Y, Kadoguchi T, Isobe S, Ohtomo F, Sano M, Shimada K, Iwakura Y, Daida H
- Journal Title
  
  International Journal of Cardiology
  
  Volume: 270 Pages: 221-227
- DOI
  10.1016/j.ijcard.2018.05.072
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K17935, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-18H02671, KAKENHI-PROJECT-16K09522, KAKENHI-PROJECT-16K16607
[Journal Article] Suppression of IL-17F, but not of IL-17A, provides protection against colitis by inducing T<sub>reg</sub> cells through modification of the intestinal microbiota.2018
- Author(s)
  Tang C, Kakuta S, Shimizu K, Kadoki M, Kamiya T, Shimazu T, Kubo S, Saijo S, Ishigame H, Nakae S, Iwakura Y.
- Journal Title
  
  Nature immunology
  
  Volume: 19 Pages: 755-765
- DOI
  10.1038/s41590-018-0134-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19437, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-18H02671
[Journal Article] Interleukin-17-producing γδT (γδ17) cells in inflammatory diseases2018
- Author(s)
  Aoi Akitsu, Yoichiro Iwakura
- Journal Title
  
  Immunology
  
  Volume: 155 Pages: 418-426
- DOI
  10.1111/imm.12993
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-18H02671
[Journal Article] IL-6, IL-17 and Stat3 are required for auto-inflammatory syndrome development in mouse2018
- Author(s)
  Oike T, Kanagawa H, Sato Y, Kobayashi T, Nakatsukasa H, Miyamoto K, Nakamura S, Kaneko Y, Kobayashi S, Harato K, Yoshimura A, Iwakura Y, Takeuchi T, Matsumoto M, Nakamura M, Niki Y, Miyamoto T.
- Journal Title
  
  Sci Rep
  
  Volume: - Pages: 15783-15783
- DOI
  10.1038/s41598-018-34173-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15198, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-18H02671, KAKENHI-PROJECT-18H02930, KAKENHI-PROJECT-16K10917
[Journal Article] TLR-stimulated IRAKM activates caspase-8 inflammasome in microglia and promotes neuroinflammation.2018
- Author(s)
  Zhang Cun-Jin、Jiang Meiling、Zhou Hao、Liu Weiwei、Wang Chenhui、Kang Zizhen、Han Bing、Zhang Quanri、Chen Xing、Xiao Jianxin、Fisher Amanda、Kaiser William J.、Murayama Masanori A.、Iwakura Yoichiro、Gao Ji、Carman Julie、Dongre Ashok、Dubyak George、Abbott Derek W.、Shi Fu-Dong、Ransohoff Richard M.、Li Xiaoxia
- Journal Title
  
  The Journal of clinical investigation
  
  Volume: 128 Pages: 5399-5412
- DOI
  10.1172/jci121901
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-18H02671
[Journal Article] LC3-Associated Phagocytosis Is Required for Dendritic Cell Inflammatory Cytokine Response to Gut Commensal Yeast Saccharomyces cerevisiae.2017
- Author(s)
  Lamprinaki, D., Beasy, G., Zhekova, A., Wittmann, A., James, S., Dicks, J., Iwakura, Y., Saijo, S., Wang, X., Chow, C. W., Roberts, I., Korcsmaros, T., Mayer, U., Wileman, T., and Kawasaki, N.
- Journal Title
  
  Front Immunol.
  
  Volume: 8 Pages: 1397-1397
- DOI
  10.3389/fimmu.2017.01397
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-16K15271
[Journal Article] Protein tyrosine phosphatase δ mediates the Sema3A-induced cortical basal dendritic arborization through the activation of Fyn tyrosine kinase.2017
- Author(s)
  Nakamura F, Okada T, Shishikura M, Uetani N, Taniguchi M, Yagi T, Iwakura Y, Ohshima T, Goshima Y, Strittmatter SM.
- Journal Title
  
  J. Neurosci.
  
  Volume: 37 Pages: 7125-7139
- DOI
  10.1523/jneurosci.2519-16.2017
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07062, KAKENHI-PROJECT-16K08447, KAKENHI-PROJECT-15H05787
[Journal Article] Advanced glycation end products induce brain-derived neurotrophic factor release from human plateltets through the Src-family kinase activation.2017
- Author(s)
  Furukawa, K. Fuse, I. Iwakura, Y. Sotoyama, H. Hanyu, O. Nawa, H. Sone, H. Takei, N.
- Journal Title
  
  Cardiovasc. Diabetol.
  
  Volume: 16 Pages: 20-20
- DOI
  10.1186/s12933-017-0505-y
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26350885, KAKENHI-PROJECT-16K07053, KAKENHI-PROJECT-15H05787
[Journal Article] Megakaryocytes compensate for Kit insufficiency in murine arthritis.2017
- Author(s)
  Cunin, P., Penke, L. R., Thon, J. N., Monach, P. A., Jones, T., Chang, M. H., Chen, M. M., Melki, I., Lacroix, S., Iwakura, Y., Ware, J., Gurish, M. F., Italiano, J. E., Boilard, E., and Nigrovic, P. A.
- Journal Title
  
  J. Clin. Invest.
  
  Volume: 27 Pages: 1714-1724
- DOI
  10.1172/jci84598
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05787
[Journal Article] Neutralization of either IL-17A or IL-17F is sufficient to inhibit house dust mite induced allergic asthma in mice.2017
- Author(s)
  Chenuet, P., Fauconnier, L., Madouri. F., Marchiol, T., Rouxel, N., Ledru, A., Mauny, P., Lory, R., Uttenhove, C., van Snick. J., Iwakura, Y., di Padova, F., Quesniaux, V., Togbe, D., and Ryffel, B.
- Journal Title
  
  Clin. Sci. (Lond)
  
  Volume: 131 Pages: 2533-2548
- DOI
  10.1042/cs20171034
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05787
[Journal Article] Pre-Transplantation Blockade of TNF-alpha-Mediated Oxygen Species Accumulation Protects Hematopoietic Stem Cells2017
- Author(s)
  Ishida T, Suzuki S, Lai CY, Yamazaki S, Kakuta S, Iwakura Y, Nojima M, Takeuchi Y, Higashihara M, Nakauchi H, Otsu M.
- Journal Title
  
  Stem Cells
  
  Volume: 35 Pages: 989-1002
- DOI
  10.1002/stem.2524
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-16H02661, KAKENHI-PROJECT-25713037, KAKENHI-PROJECT-15K20949
[Journal Article] IL-17A-deficient mice are highly susceptible to Toxoplasma gondii infection due to excessively induced T. gondii HSP70 and IFN-γ production.2017
- Author(s)
  Moroda M, Takamoto M, Iwakura Y, Nakayama J, Aosai F
- Journal Title
  
  Infect. Immun.
  
  Volume: 85 Pages: 00399-17
- DOI
  10.1128/iai.00399-17
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15255, KAKENHI-PROJECT-15H05787
[Journal Article] IL-17A contributes to reducing IFN-γ/IL-4 ratio and persistence of Entamoeba histolytica during intestinal amebiasis.2017
- Author(s)
  Deloer, S. Nakamura, R. Kikuchi, M. Moriyasu, T. Kalenda, Y. D. J. Mohammed, E. S. Senba, M. Iwakura, Y. Yoshida, H. Hamano, S.
- Journal Title
  
  Parasitology International
  
  Volume: 66 Pages: 817-823
- DOI
  10.1016/j.parint.2017.09.011
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08842, KAKENHI-PROJECT-26305013, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-17H04649, KAKENHI-PROJECT-16K19118
[Journal Article] Dectin-1 Plays an Important Role in House Dust Mite-Induced Allergic Airway Inflammation through the Activation of CD11b+ Dendritic Cells.2017
- Author(s)
  Ito T, Hirose K, Norimoto A, Tamachi T, Yokota M, Saku A, Takatori H, Saijo S, Iwakura Y, Nakajima H.
- Journal Title
  
  J Immunol
  
  Volume: 198 Pages: 61-70
- DOI
  10.4049/jimmunol.1502393
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-26293094, KAKENHI-PROJECT-26461184, KAKENHI-PROJECT-16K09573, KAKENHI-PROJECT-16K15271
[Journal Article] Nociceptors Boost the Resolution of Fungal Osteoinflammation via the TRP Channel-CGRP-Jdp2 Axis.2017
- Author(s)
  Maruyama Kenta、Takayama Yasunori、Kondo Takeshi、Ishibashi Ken-ichi、Sahoo Bikash Ranjan、Kanemaru Hisashi、Kumagai Yutaro、Martino Mika?l M.、Tanaka Hiroki、Ohno Naohito、Iwakura Yoichiro、Takemura Naoki、Tominaga Makoto、Akira Shizuo
- Journal Title
  
  Cell Rep.
  
  Volume: 19 Pages: 2730-2742
- DOI
  10.1016/j.celrep.2017.06.002
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15725, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-15H02501, KAKENHI-PROJECT-15H05686, KAKENHI-PROJECT-16K15665, KAKENHI-PROJECT-16K19148
[Journal Article] Phospholipase Cδ1 regulates p38 MAPK activity and skin barrier integrity2017
- Author(s)
  Kaori Kanemaru, Yoshikazu Nakamura, Kengo Totoki, Takatsugu Fukuyama, Madoka Shoji, Hisae Kaneko, Kanako Shiratori, Atsuko Yoneda, Takafumi Inoue, Yoichiro Iwakura, Kenji Kabashima, Kiyoko Fukami
- Journal Title
  
  Cell Death Differ.
  
  Volume: in press Pages: 1079-1090
- DOI
  10.1038/cdd.2017.56
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293071, KAKENHI-PROJECT-26440036, KAKENHI-PROJECT-15K15417, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-17H04051
[Journal Article] IL-17A promotes neutrophilic inflammation and disturbs acute wound healing in skin2017
- Author(s)
  Takagi N, Kawakami K, Kanno E, Tanno H, Takeda A, Ishii K, Imai Y, Iwakura Y, Tachi M.
- Journal Title
  
  Exp Dermatol.
  
  Volume: 26 Pages: 137-144
- DOI
  10.1111/exd.13115
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-15H06052, KAKENHI-PROJECT-26462723
[Journal Article] Elevation of pro-inflammatory cytokine levels following anti-resorptive drug treatment is required for osteonecrosis development in infectious osteomyelitis.2017
- Author(s)
  Morita M, Iwasaki R, Sato Y, Kobayashi T, Watanabe R, Oike T, Nakamura S, Keneko Y, Miyamoto K, Ishihara K, Iwakura Y, Ishii K, Matsumoto M, Nakamura M, Kawana H, Nakagawa T, Miyamoto T.
- Journal Title
  
  Sci Rep
  
  Volume: 7 Pages: 46322-46322
- DOI
  10.1038/srep46322
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10917, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-15H04963, KAKENHI-PROJECT-15K10490, KAKENHI-PROJECT-15K11023
[Journal Article] An ocular commensal protects from corneal infection by driving an IL-17 response from mucosal γδT cells.2017
- Author(s)
  St Leger, A. J., Desal, J. V., Drummond, R. A., Kugadas, A., Almaghrabi, F., Silver, P., Raychaudhuri, K., Gadjeva, M., Iwakura, Y., Lionakis, M., and Caspi, R. R.
- Journal Title
  
  Immunity
  
  Volume: 47 Pages: 148-158
- DOI
  10.1016/j.immuni.2017.06.014
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05787
[Journal Article] The mycobacterial phosphatase PtpA regulates the expression of host genes and promotes cell proliferation.2017
- Author(s)
  Wang, J., Ge, P., Qiang, L., Tian, F., Zhao, D., Chai, Q., Zhu, M., Zhou, R., Meng, G., Iwakura, Y., Gao, G. F., and Liu, C. H.
- Journal Title
  
  Nat. Commun.
  
  Volume: 8 Pages: 244-244
- DOI
  10.4049/jimmunol.1700655
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05787
[Journal Article] Fungal-derived cues promote ocular autoimmunity through a Dectin-2/Card9-mediated mechanism.2017
- Author(s)
  Brown, B. R., Lee, E. J., Snow, P. E., Vance, E. E., Iwakura, Y., Ohno, N., Miura, N., Lin, X., Brown, G. D., Wells, C. A., Smith, J. R., Caspi, R. R., and Rosenzweig, H. L.
- Journal Title
  
  Clin. Exp. Immunol.
  
  Volume: 190 Pages: 293-303
- DOI
  10.1111/cei.13021
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05787
[Journal Article] Absence of DCIR1 reduces the mortality rate of endotoxemic hepatitis in mice2017
- Author(s)
  Ishiguro T, Fukawa T, Akaki K, Nagaoka K, Takeda T, Iwakura Y ,Inaba K, Takahara K.
- Journal Title
  
  Eur. J. Immunol.
  
  Volume: 47 Pages: 704-712
- DOI
  10.1002/eji.201646814
- NAID
  120006414202
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-16K08737
[Journal Article] Modulation of an innate immune response by soluble yeast β-glucan prepared by a heat degradation method.2017
- Author(s)
  Ishimoto, Y., Ishibashi, K. I., Yamanaka, D., Adachi, Y., Kanzaki, K., Okita, K., Iwakura, Y., and Ohno, N.
- Journal Title
  
  Int. J. Biol. Macromol.
  
  Volume: 104 Pages: 367-376
- DOI
  10.1016/j.ijbiomac.2017.06.036
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05787
[Journal Article] Dectin-2 deficiency modulates Th1 differentiation and improves wound healing after myocardial infarction.2017
- Author(s)
  Yan, X., Zhang, H., Fan, Q., Hu, J., Tao, R., Chen, Q., Iwakura, Y., Shen, W., Lu, L., Zhang, Q., and Zhang, R.
- Journal Title
  
  Circ. Res.
  
  Volume: 120 Pages: 1116-1129
- DOI
  10.1161/circresaha.116.310260
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05787
[Journal Article] Brain interleukin-1 facilitates learning of a water maze spatial memory task in young mice.2017
- Author(s)
  Takemiya T, Fumizawa K, Yamagata K, Iwakura Y, Kawakami M.
- Journal Title
  
  Front Behav Neurosci.
  
  Volume: 11 Pages: 202-202
- DOI
  10.3389/fnbeh.2017.00202
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10064, KAKENHI-PROJECT-25293239, KAKENHI-PROJECT-15H05787
[Journal Article] IL-17A promotes neutrophilic inflammation and disturbs acute wound healing in skin.2017
- Author(s)
  Takagi N, Kawakami K, Kanno E, Tanno H, Takeda A, Ishii K, Imai Y, Iwakura Y, Tachi M
- Journal Title
  
  Dermatol.
  
  Volume: 26 Pages: 137-144
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05787
[Journal Article] Preferencially expanding Vγ1+ γδ T cells are associated with protective immunity against Plasmodium infection in mice.2017
- Author(s)
  Inoue SI, Niikura M, Asahi H, Iwakura Y, Kawakami Y, Kobayashi F.
- Journal Title
  
  Eur J Immunol
  
  Volume: 47 Pages: 685-691
- DOI
  10.1002/eji.201646699
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-15K08449, KAKENHI-PROJECT-15K08451, KAKENHI-PROJECT-15K19085
[Journal Article] Macrophage-derived IL-1α promotes sterile inflammation in a mouse model of acetaminophen hepatotoxicity.2017
- Author(s)
  Zhang, C., Feng, J., Du, J., Zhuo, Z., Yang, S., Zhang, W., Wang, W., Zhang, S., Iwakura, Y., Meng, G., Fu, Y. X., Hou, B., and Tang, H.
- Journal Title
  
  Cell. Mol. Immunol.
  
  Volume: -
- DOI
  10.1038/cmi.2017.22
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05787
[Journal Article] The innate immune receptor Dectin-2 mediates the phagocytosis of cancer cells by Kupffer cells for the suppression of liver metastasis2016
- Author(s)
  Kimura Y., Inoue A.., Hangai S.., Saijo S., Negishi H., Nishio J., Yamasaki S., Iwakura Y., Yanai H., Taniguchi T.
- Journal Title
  
  Proceedings of National Academy of Sciences of the United States of America
  
  Volume: 113 Pages: 14097-14102
- DOI
  10.1073/pnas.1617903113
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-16H06747, KAKENHI-PROJECT-26293094, KAKENHI-PROJECT-16K15271
[Journal Article] IL-21 inhibits IL-17A-producing γδ T cell response after infection with Bacillus Calmette-Guerin via induction of apoptosis.2016
- Author(s)
  Huang Y., Matsumura Y., Hatano, S., Noguchi N., Murakamia, T., Iwakura Y., Sun X., Oharad N., Yoshikai Y.
- Journal Title
  
  Innate Immun.
  
  Volume: 22 Pages: 588-597
- DOI
  10.1177/1753425916664125
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06496, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-26293098
[Journal Article] IL-17A-producing CD30+ Vδ1 T cells drive inflammation-induced cancer progression2016
- Author(s)
  Kimura Y, Nagai N, Tsunekawa N, Sato-Matsushita M, Yoshimoto T, Cua DJ, Iwakura Y, Yagita H, Okada F, Tahara H, Saiki I, Irimura T, Hayakawa Y.
- Journal Title
  
  Cancer Sci
  
  Volume: 107 Pages: 1106-1214
- DOI
  10.1111/cas.13005
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-15J11569, KAKENHI-PROJECT-25293011, KAKENHI-PROJECT-26290059, KAKENHI-PROJECT-26430158, KAKENHI-PROJECT-26460472, KAKENHI-PROJECT-15K07947, KAKENHI-PROJECT-15K08433, KAKENHI-PROJECT-15K08902, KAKENHI-PROJECT-26670023
[Journal Article] Regulation of Inflammation by IL-17A and IL-17F Modulates Non-Alcoholic Fatty Liver Disease Pathogenesis.2016
- Author(s)
  Giles, D. A., Moreno-Fernandez, M. E., Stankiewicz, T. E., Cappelletti, M., Huppert, S. S., Iwakura, Y., Dong, C., Shanmukhappa, S. K., and Divanovic, S.
- Journal Title
  
  Plos One
  
  Volume: 11
- DOI
  10.1371/journal.pone.0149783
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011
[Journal Article] Mesenteric lymph nodes contribute to proinflammatory Th17-cell generation during inflammation of the small intestine in mice2016
- Author(s)
  Kawabe, T., Suzuki, N., Yamaki, S., Sun, S. L., Asao, A., Okuyama, Y., So, T., Iwakura, Y., and Ishii, N.
- Journal Title
  
  Eur J Immunol
  
  Volume: 46 Pages: 1119-1131
- DOI
  10.1002/eji.201545907
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-15H04640, KAKENHI-PROJECT-15H04742
[Journal Article] The potential for repositioning antithyroid agents as antiasthma drugs2016
- Author(s)
  Suzuki S, Ogawa M, Ohta S, Arima K, Nunomura S, Nanri Y, Mitamura Y, Yoshihara T, Nakamura Y, Yamauchi K, Chibana K, Ishii Y, Lee JJ, Aratani Y, Kakuta S, Kubo S, Iwakura Y, Yoshida H, Izuhara K.
- Journal Title
  
  J Allergy Clin Immunol
  
  Volume: 138 Pages: 1458-1461
- DOI
  10.1016/j.jaci.2016.04.047
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-16H05343, KAKENHI-PROJECT-25461164, KAKENHI-PROJECT-26450446, KAKENHI-PROJECT-15K09553, KAKENHI-PROJECT-16K08842, KAKENHI-PROJECT-15K15372
[Journal Article] Adiponectin enhances antibacterial activity of hematopoietic cells by suppressing bone marrow inflammation.2016
- Author(s)
  Masamoto Y, Arai S, Sato T, Yoshimi A, Kubota N, Takamoto I, Iwakura Y, Yoshimura A, Kadowaki T, Kurokawa M.
- Journal Title
  
  Immunity
  
  Volume: 44 Pages: 1422-1433
- DOI
  10.1016/j.immuni.2016.05.010
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01481, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-25221305, KAKENHI-PROJECT-16K15500, KAKENHI-PROJECT-26000012
[Journal Article] Expression of Concern. Low Concentration of Interleukin-1β Induces FLICE-Inhibitory Protein-Mediated β-Cell Proliferation in Human Pancreatic Islets.2016
- Author(s)
  Maedler K, Schumann DM, Sauter N, Ellingsgaard H, Bosco D, Baertschiger R, Iwakura Y, Oberholzer J, Wollheim CB, Gauthier BR, Donath MY.
- Journal Title
  
  Diabetes.
  
  Volume: 65
- DOI
  10.2337/db16-ec08a
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011
[Journal Article] Isolation of joint-infiltrating cells.2016
- Author(s)
  Akitsu A, Iwakura Y.
- Journal Title
  
  Bio-Protocol.
  
  Volume: 6
- DOI
  10.21769/bioprotoc.1911
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011
[Journal Article] Involvement of IL-17A-producing TCR γδ T cells in late protective immunity against pulmonary Mycobacterium tuberculosis infection. Immun2016
- Author(s)
  Umemura M, Okamoto-Yoshida Y, Yahagi A, Touyama S, Nakae S, Iwakura Y, Matsuzaki G.
- Journal Title
  
  Immunity, Inflammation and Disease
  
  Volume: 4 Pages: 401-412
- DOI
  10.1002/iid3.121
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-15K08468
[Journal Article] IL-17-producing γ δ T cells enhance bone regeneration2016
- Author(s)
  Ono T, Okamoto K, Nakashima T, Nitta T, Hori S, Iwakura Y, Takayanagi H.
- Journal Title
  
  Nat Commun.
  
  Volume: 7 Pages: 10928-10928
- DOI
  10.1038/ncomms10928
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04747, KAKENHI-PROJECT-15H05653, KAKENHI-PROJECT-14J03013, KAKENHI-PROJECT-25460606, KAKENHI-PROJECT-25670773, KAKENHI-PROJECT-15H05703, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-16H05506
[Journal Article] IL-1 receptor antagonist inhibits pancreatic cancer growth by abrogating NF-κB activation.2016
- Author(s)
  Zhuang, Z. N., Ju, H. Q., Aguilar, M., Gocho, T., Li, H., Iida, T., Lee, H., Fan, X., Zhou, H., Ling, J., Li, Z., Fu, J., Wu, M., Li, M., Melisi, D., Iwakura, Y., Xu, K., Fleming, J. B., and Chiao, P. J.
- Journal Title
  
  Clin. Cancer Res.
  
  Volume: 22 Pages: 1432-1444
- DOI
  10.1158/1078-0432.ccr-14-3382
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011
[Journal Article] Inhaled Fine Particles Induce Alveolar Macrophage Death and Interleukin-1α Release to Promote Inducible Bronchus-Associated Lymphoid Tissue Formation2016
- Author(s)
  Kuroda E, Ozasa K, Temizoz B, Ohata K, Koo CX, Kanuma T, Kusakabe T, Kobari S, Horie M, Morimoto Y, Nakajima S, Kabashima K, Ziegler SF, Iwakura Y, Ise W, Kurosaki T, Nagatake T, Kunisawa J, Takemura N, Uematsu S, Hayashi M, Aoshi T, Kobiyama K, Coban C, Ishii KJ.
- Journal Title
  
  Immunity
  
  Volume: 45(6) Pages: 1299-1310
- DOI
  10.1016/j.immuni.2016.11.010
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01367, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-26221306, KAKENHI-PROJECT-16H05256, KAKENHI-PROJECT-15K14404, KAKENHI-PROJECT-15K19142, KAKENHI-PROJECT-16K15289, KAKENHI-PROJECT-15H05790, KAKENHI-PROJECT-16K19148
[Journal Article] Expression of receptor protein tyrosine phosphatase δ, PTPδ, in mouse central nervous system2016
- Author(s)
  Shishikura, M., Nakamura, F., Yamashita, N., Uetani, N., Iwakura, Y., and Goshima, Y.
- Journal Title
  
  Brain Res
  
  Volume: 1642 Pages: 244-254
- DOI
  10.1016/j.brainres.2016.03.030
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-16K07062
[Journal Article] A critical role of Dectin-1 in hypersensitivity pneumonitis.2016
- Author(s)
  Higashino-Kameda M, Yabe-Wada T, Matsuba S, Takeda K, Anzawa K, Mochizuki T, Makimura K, Saijo S, Iwakura Y, Toga H, Nakamura A
- Journal Title
  
  Inflamm Res.
  
  Volume: 65 Pages: 235-244
- DOI
  10.1007/s00011-015-0910-1
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-INTERNATIONAL-15K21745, KAKENHI-ORGANIZER-15H05935, KAKENHI-PROJECT-25460601, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-26293094, KAKENHI-PROJECT-16K09703, KAKENHI-PROJECT-16K15271
[Journal Article] Phosphoinositide 3-Kinase δ Regulates Dectin-2 Signaling and the Generation of Th2 and Th17 Immunity.2016
- Author(s)
  Lee MJ, Yoshimoto E, Saijo S, Iwakura Y, Lin X, Katz HR, Kanaoka Y, Barrett NA.
- Journal Title
  
  J Immunol.
  
  Volume: 197 Pages: 278-287
- DOI
  10.4049/jimmunol.1502485
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-26293094, KAKENHI-PROJECT-16K15271
[Journal Article] Two types of IL-17A-producing γδ T cells in protection against pulmonary infection with Klebsiella pneumoniae.2016
- Author(s)
  Murakami T., Hatano S., Yamada H., Iwakura Y., Yoshikai Y.
- Journal Title
  
  J Infect Dis.
  
  Volume: 214 Pages: 1752-1761
- DOI
  10.1093/infdis/jiw443
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-16H06496, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-26293098
[Journal Article] Immune Complexes Indirectly Suppress the Generation of Th17 Responses In Vivo.2016
- Author(s)
  Ciraci, C., Janczy, J. R., Jain, N., Haasken, S., Pecli, E. Silva, C., Benjamim, C. F., Sadler, J. J., Olivier. A. K., Iwakura, Y., Shayakhmetov, D. M., Sutterwala, F. S., and Cassel, S. L.
- Journal Title
  
  Plos One
  
  Volume: 11
- DOI
  10.1371/journal.pone.0151252
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011
[Journal Article] T cell-intrinsic ASC critically promotes T(H)17-mediated experimental autoimmune encephalomyelitis.2016
- Author(s)
  Martin, B. N. , et al.
- Journal Title
  
  Nat Immunol.
  
  Volume: 17 Pages: 583-592
- DOI
  10.1038/ni.3389
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011
[Journal Article] IL-17A exacerbates cisplatin-based resistance of OVCA via upregulating the expression of ABCG2 and MDR1 through Gli1-mediated Hh signaling.2016
- Author(s)
  Niu X, Liu W, Wang Y, Liu X, Zhang H, Li Z, Li H, Iwakura Y, Deng W.
- Journal Title
  
  Oncotarget
  
  Volume: 印刷中
- DOI
  10.18632/oncotarget.10655
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] Interleukin-17A Promotes Aortic Endothelial Cell Activation via Transcriptionally and Post-translationally Activating p38 Mitogen-activated Protein Kinase (MAPK) Pathway.2016
- Author(s)
  Mai, J., Nanayakkara, G., Lopez-Pastrana, J., Li, X., Li, Y. F., Wang, X., Song, A., Virtue, A., Shao, Y., Shan, H., Liu, F., Autieri, M. V., Kunapuli, S. P., Iwakura, Y., Jiang, X., Wang, H., Yang, X. F.
- Journal Title
  
  J Biol Chem.
  
  Volume: 291 Pages: 4939-4954
- DOI
  10.1074/jbc.m115.690081
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011
[Journal Article] Dectin-1 and Dectin-2 promote control of the fungal pathogen Trichophyton rubrum independently of IL-17 and adaptive immunity in experimental deep dermatophytosis.2016
- Author(s)
  Fabio Yoshikawa, Rikio Yabe, Yoichiro Iwakura, Sandro Rogerio de Almeida, Shinobu Saijo
- Journal Title
  
  Innate Immun.
  
  Volume: in press Pages: 316-24
- DOI
  10.1177/1753425916645392
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293094, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-16K15271, KAKENHI-PROJECT-16K19147
[Journal Article] Cross reactivity of S. aureus to murine cytokine assays: A source of discrepancy.2016
- Author(s)
  Javed, N., Xue, G., Lu, A., Xing, Y., Iwakura, Y., Xiao, H., Lecoeur, H., Spath, G. F., and Meng, G.
- Journal Title
  
  Cytokine
  
  Volume: 81 Pages: 101-108
- DOI
  10.1016/j.cyto.2016.03.007
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011
[Journal Article] Dectin-2-dependent host defense in mice infected with serotype 3 Streptococcus pneumoniae.2016
- Author(s)
  Akahori Y, Miyasaka T, Toyama M, Matsumoto I, Miyahara A, Zong T, Ishii K, Kinjo Y, Miyazaki Y, Saijo S, Iwakura Y, Kawakami K.
- Journal Title
  
  BMC Immunol.
  
  Volume: 17 Pages: 1-1
- DOI
  10.1186/s12865-015-0139-3
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25713038, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-26293094, KAKENHI-PROJECT-16K15271
[Journal Article] Mincle Activation and the Syk/Card9 Signaling Axis Are Central to the Development of Autoimmune Disease of the Eye.2016
- Author(s)
  Lee, E. J., Brown, B. R., Vance, E. E., Snow, P. E., Silver, P. B., Heinrichs, D., Lin, X., Iwakura, Y., Wells, C. A., Caspi, R. R., and Rosenzweig, H. L.
- Journal Title
  
  J Immunol.
  
  Volume: 196 Pages: 3148-3158
- DOI
  10.4049/jimmunol.1502355
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011
[Journal Article] Interleukin-17A Regulates Renal Sodium Transporters and Renal Injury in Angiotensin II-Induced Hypertension.2016
- Author(s)
  Norlander AE, Saleh MA, Kamat NV, Ko B, Gnecco J, Zhu L, Dale BL, Iwakura Y, Hoover RS, McDonough AA, Madhur MS.
- Journal Title
  
  Hypertension
  
  Volume: 68 Pages: 167-74
- DOI
  10.1161/hypertensionaha.116.07493
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011
[Journal Article] Dectin-2 Recognizes Mannosylated O-antigens of Human Opportunistic Pathogens and Augments Lipopolysaccharide Activation of Myeloid Cells.2016
- Author(s)
  Wittmann A, Lamprinaki D, Bowles KM, Katzenellenbogen E, Knirel YA, Whitfield C, Nishimura T, Matsumoto N, Yamamoto K, Iwakura Y, Saijo S, Kawasaki N.
- Journal Title
  
  J Biol Chem.
  
  Volume: 291 Pages: 17629-17638
- DOI
  10.1074/jbc.m116.741256
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-26293094, KAKENHI-PROJECT-16K15271
[Journal Article] Bone marrow transplantation alters lung antigen-presenting cells to promote Th17 reponse and the development of pneumonitis and fibrosis following gammaherpesvirus infection.2016
- Author(s)
  Zhou, X., Loomis-King, H., Gurczynski, S. J., Wilke, C. A., Konopka, K. E., Ptaschinski, C., Coomes, S. M., Iwakura, Y., van Dyk, L. F., Lukacs, N. W., and Moore, B. B.
- Journal Title
  
  Mucosal Immunol
  
  Volume: 9 Pages: 610-20
- DOI
  10.1038/mi.2015.85
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011
[Journal Article] Mouse model for PTPRD associations with WED/RLS and addiction: reduced expansion alters locomotion, sleep behaviors and cocaine-conditioned place preference.2015
- Author(s)
  Drgonova, J., Walther, D., Wang, K. J., Hartstein, G. L., Lochte, B., Troncoso, J., Uetani, N., Iwakura, Y., and Uhl, G. R.
- Journal Title
  
  Mol. Med.
  
  Volume: 21 Pages: 717-725
- DOI
  10.2119/molmed.2015.00017
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011
[Journal Article] IL-1 receptor-antagonist (IL-1Ra) knockout mice show anxiety-like hehavior by aging.2015
- Author(s)
  Wakabayashi et al.
- Journal Title
  
  Neuroscience Letters
  
  Volume: 599 Pages: 20-25
- DOI
  10.1016/j.neulet.2015.05.019
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K14309, KAKENHI-PROJECT-23220008, KAKENHI-PROJECT-24300139, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011
[Journal Article] CD11c+ DCs accelerate the rejection of older cardiac transplants via IL-17A.2015
- Author(s)
  Oberhuber, R., Heinbokel, T., Cetina Biefer, H. R., Boenisch, O., Hock, K., Bronson, R. T., Wilhelm, M. J., Iwakura, Y., Edtinger, K., Uehara, H., Quante, M., Voskuil, F., Krenzien, F., Slegtenhorst, B., Abdi, R., Pratschke, J., Elkhal, A., and Tullius, S. G.
- Journal Title
  
  Circulation
  
  Volume: 132 Pages: 122-131
- DOI
  10.1161/circulationaha.114.014917
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011
[Journal Article] Inhibition of Dectin-1 signaling ameliorates colitis by inducing Lactobacillus-mediated regulatory T cell expansion in the intestine.2015
- Author(s)
  Ce Tang, Tomonori Kamiya, Yang Liu, Motohiko Kadoki, Shigeru Kakuta, Kenshiro Oshima, Masahira Hattori, Kozue Takeshita, Takanori Kanai, Shinobu Saijo and Yoichiro Iwakura
- Journal Title
  
  Cell Host Microbe
  
  Volume: 18 Pages: 183-197
- DOI
  10.1016/j.chom.2015.07.003
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26830058, KAKENHI-PROJECT-26293094, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011
[Journal Article] Exacerbation of experimental autoimmune encephalomyelitis in mice deficient for DCIR, an inhibitory C-type lectin receptor.2015
- Author(s)
  Seno, A., Maruhashi, T., Kaifu, T., Yabe, R., Fujikado, N., Ma, G., Ikarashi, T., Kakuta, S., and *Iwakura, Y.
- Journal Title
  
  Exp. Anim.
  
  Volume: 未定
- NAID
  130005069862
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] CCR8 regulates contact hypersensitivity by restricting cutaneous dendritic cell migration to the draining lymph nodes.2015
- Author(s)
  Yabe, R., Shimizu, K., Shimizu, S., Azechi, S., Choi, B. I., Sudo, K., Kubo, S., Nakae, S., Ishigame, H., Kakuta, S., and Iwakura, Y.
- Journal Title
  
  Int. Immunol.
  
  Volume: 27（４） Pages: 169-181
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] A cruciall role of RORγt in the development of spontaneous sialadenitis-like Sjogren’s syndrome.2015
- Author(s)
  Iizuka, M., Tsuboi, H., Matsuo, N., Asashima, H., Hirota, T., Kondo, Y., Iwakura, Y., Takahashi, S., Matsumoto, I., Sumida, T.
- Journal Title
  
  J. Immunol.
  
  Volume: 194(1) Pages: 56-67
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] Dectin-2 deficiency promotes Th2 response and mucin production in the lungs after pulmonary infection with Cryptococcus neoformans.2015
- Author(s)
  Nakamura Y, Sato K, Yamamoto H, Matsumura K, Matsumoto I, Nomura T, Miyasaka T, Ishii K, Kanno E, Tachi M, Yamasaki S, Saijo S, Iwakura Y, Kawakami K.
- Journal Title
  
  Infect Immun
  
  Volume: 83 Pages: 671-681
- DOI
  10.1128/iai.02835-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390101, KAKENHI-PLANNED-26110009, KAKENHI-PROJECT-26293094, KAKENHI-PROJECT-26293099, KAKENHI-PROJECT-26670213
[Journal Article] Interleukin-1 receptor type 2 suppresses collagen-induced arthritis by inhibiting interleukin-1 signal on macrophages.2015
- Author(s)
  Shimizu K, Nakajima A, Sudo K, Liu Y, Mizoroki A, Ikarashi T, Horai R, Kakuta S, Watanabe T, Iwakura Y.
- Journal Title
  
  J. Immunol
  
  Volume: 194(7) Pages: 3156-3168
- DOI
  10.4049/jimmunol.1402155
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24500488, KAKENHI-PROJECT-26461961, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011
[Journal Article] α-Mannan induces Th17-mediated pulmonary graft-versus-host disease in mice.2015
- Author(s)
  Uryu H, Hashimoto D, Kato K, Hayase E, Matsuoka S, Ogasawara R, Takahashi S, Maeda Y, Iwasaki H, Miyamoto T, Saijo S, Iwakura Y, Hill GR, Akashi K, Teshima T.
- Journal Title
  
  blood
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293094
[Journal Article] Antibiotic-killed Staphyococcus aureus induces detructive arthritis in mice.2015
- Author(s)
  Ali, A., Zhu, X., Kwiecinski, J., Gjertsson, I., Lindholm, C., Iwakura, Y., Wang, X., Lycke, N., Josefsson, E., Pullerits, R., and Jin, T.
- Journal Title
  
  Arthritis Rheumatol.
  
  Volume: 67（1） Pages: 107-116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] CTRP6 is an endogenous complement regulator that can effectively treat induced arthritis.2015
- Author(s)
  Murayama A.M, Kakuta S, Inoue A, Umeda N, Yonezawa T, Maruhashi T, Tateishi K, Ishigame H, Yabe R, Ikeda S, Seno A, Chi H-H, Hashiguchi Y, Kurata R, Tada T, Kubo S, Sato N, Liu Y, Hattori M, Saijo S, Matsushita M, Fujita T, Sumida T, Iwakura Y
- Journal Title
  
  Nat. Commun.
  
  Volume: 6 Pages: 1-12
- DOI
  10.1038/ncomms9483
- NAID
  120005672443
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26450448, KAKENHI-PROJECT-26293094, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011
[Journal Article] Interdependence between interleukin-1 and tumor necrosis factor regulates TNF-dependent control of Mycobacterium tuberculosis infection.2015
- Author(s)
  Di Paolo, N. C., Shafiani, S., Day, T., Papayannoupoulou, T., Russell, D. W., Iwakura, Y., Sherman, D., Urdahl, K., and Shayakhmetov, D. M.
- Journal Title
  
  Immunity
  
  Volume: 43 Pages: 1125-36
- DOI
  10.1016/j.immuni.2015.11.016
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011
[Journal Article] IL-1R Type 2 Suppresses Collagen-Induced Arthritis Inhibiting IL-1 Signal on Macrophages.2015
- Author(s)
  Shimizu K, Nakajima A, Sudo K, Yang L, Mizoroki A, Ikarashi T, Horai R, Kakuta S, Watanabe T, and Iwakura Y.
- Journal Title
  
  J Immunol.
  
  Volume: 194（７） Pages: 3156-68
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] Dendritic cell immunoreceptor 1 alters neutrophil response in the development of experimental colitis.2015
- Author(s)
  Tokieda, S., Komori, M., Ishiguro, Iwakura, Y., Takahara, K.* and Inaba, K.
- Journal Title
  
  BMC Immunol
  
  Volume: 16 Pages: 64-64
- DOI
  10.1186/s12865-015-0129-5
- NAID
  120005689211
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460494, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011
[Journal Article] DCIR in the “osteo-immune” system.2015
- Author(s)
  1.Maruhashi T, Kaifu T, and Iwakura Y
- Journal Title
  
  Oncotarget
  
  Volume: 6 Pages: 34051-2
- DOI
  10.18632/oncotarget.6043
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26430095
[Journal Article] IL-1 receptor antagonist-deficient mice develop autoimmune arthritis due to intrinsic activation of IL-17-producing CCR2+Vγ6+γδ T cells.2015
- Author(s)
  Akitsu A, Ishigame H, Kakuta S, Chung SH, Ikeda S, Shimizu K, Kubo S, Liu Y, Umemura M, Matsuzaki G, Yoshikai Y, Saijo S, Iwakura Y.
- Journal Title
  
  Nat. Commun.
  
  Volume: 6 Pages: 7464-7464
- DOI
  10.1038/ncomms8464
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08468, KAKENHI-PROJECT-25293105, KAKENHI-PROJECT-26293094, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011
[Journal Article] α-Mannan induces Th17-mediated pulmonary graft-versus-host disease in mice.2015
- Author(s)
  Uryu H, Hashimoto D, Kato K, Hayase E, Matsuoka S, Ogasawara R, Takahashi S, Maeda Y, Iwasaki H, Miyamoto T, Saijo S, Iwakura Y, Hill GR, Akashi K, Teshima T.
- Journal Title
  
  Blood.
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390101
[Journal Article] DCIR maintains bone homeostasis by regulating IFN-g;production in T cells.2015
- Author(s)
  Maruhashi T*, Kaifu T*, Yabe R, Seno A, Chung SH, Fujikado N, and Iwakura Y
- Journal Title
  
  J. Immunol.
  
  Volume: 194 Pages: 5681-5691
- DOI
  10.4049/jimmunol.1500273
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26430095, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011
[Journal Article] PGD2 deficiency exacerbates food antigen-induced mast cell hyperplasia2015
- Author(s)
  Nakamura T, Maeda S, Horiguchi K, Maehara T, Aritake K, Choi BI, Iwakura Y, Urade Y, Murata T.
- Journal Title
  
  Nat. Commun.
  
  Volume: 10;6 Pages: 7514-7514
- DOI
  10.1038/ncomms8514
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25221205, KAKENHI-PROJECT-15J10812, KAKENHI-PROJECT-25460947, KAKENHI-PROJECT-26660225, KAKENHI-PROJECT-25252049, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-26293051
[Journal Article] Filaggrin deficiency promotes the dissemination of cutaneously inoculated vaccinia virus.2015
- Author(s)
  Oyoshi, M. K., Beaupre;, J., Venturelli, N., Lewis, C. N., Iwakura, Y., Geha, R. S.
- Journal Title
  
  J. Allergy Clin. Immunol.,
  
  Volume: 未定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] Neutrophils negatively regulate induction of mucosal IgA responses after sublingual immunization.2015
- Author(s)
  Jee, J., Bonnegarde-Bernard, A., Duverger, A., Iwakura, Y., Cormet-Boyaka, E., Martin, T. L., Steiner, H. E., Bachman, R. C., and Boyaka, P. N.
- Journal Title
  
  Mucosal Immunol.
  
  Volume: 8 Pages: 735-745
- DOI
  10.1038/mi.2014.105
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05787
[Journal Article] Dectin-2 deficiency promotes Th2 response and mucin production in the lungs after pulmonary infection with Cryptococcus neoformans.2015
- Author(s)
  Nakamura, Y., Sato, K., Yamamoto, H., Matsumura, K., Matsumoto, I., Nomura, T., Miyasaka, T., Ishii, K., Kanno, E., Tachi, M., Yamasaki, S., Saijo, S., Iwakura, Y., Kawakami, K.
- Journal Title
  
  Infect. Immun.
  
  Volume: 83(2) Pages: 671-681
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] Exacerbation of experimental autoimmune encephalomyelitis in mice deficient for DCIR, an inhibitory C-type lectin receptor.2015
- Author(s)
  Seno, A., Maruhashi, T., Kaifu, T., Yabe, R., Fujikado, N., Ma, G., Ikarashi, T., Kakuta, S., and Iwakura, Y.
- Journal Title
  
  Exp. Anim.
  
  Volume: 64 Pages: 109-119
- NAID
  130005069862
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] Neutrophils negatively regulate induction of mucosal IgA responses after sublingual immunization.2015
- Author(s)
  Jee, J., Bonnegarde-Bernard, A., Duverger, A., Iwakura, Y., Cormet-Boyaka, E., Martin, T. L., Steiner, H. E., Bachman, R. C., and Boyaka, P. N.
- Journal Title
  
  Mucosal Immunol.,
  
  Volume: 未定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] IFN-γ induction by neutrophil-derived IL-17A homodimer augments pulmonary antibacterial defense.2015
- Author(s)
  Cai, S., Batra, S., Langohr, I., Iwakura, Y., and Jeyaseelan, S.
- Journal Title
  
  Mucosal Immunol
  
  Volume: 9 Pages: 718-29
- DOI
  10.1038/mi.2015.95
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011
[Journal Article] NLRP3 deficiency exacerbates hyperoxia-induced lethality through Stat3 signaling independently of interleukin-1β2015
- Author(s)
  Mizushina, Y., Shirasuna, K., Usui, F., Karasawa, T., Kawashima, A., Kimura, H., Kobayashi, M., Komada, T., Inoue, Y., Mato, N., Yamasawa, H., Latz, E., Iwakura, Y., Kasahara, T., Bando, M., Sugiyama, Y., and Takahashi, M.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 290（8） Pages: 5065-5077
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] α-Mannan induces Th17-mediated pulmonary graft-versus-host disease in mice.2015
- Author(s)
  Uryu H, Hashimoto D, Kato K, Hayase E, Matsuoka S, Ogasawara R, Takahashi S, Maeda Y, Iwasaki H, Miyamoto T, Saijo S, Iwakura Y, Hill GR, Akashi K, Teshima T.:
- Journal Title
  
  Blood
  
  Volume: 125 Pages: 3014-23
- DOI
  10.1182/blood-2014-12-615781
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22130002, KAKENHI-PROJECT-25253069, KAKENHI-PROJECT-26461438, KAKENHI-PROJECT-15K15365, KAKENHI-PROJECT-25461424, KAKENHI-PROJECT-26293094, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011
[Journal Article] Local IL-17 production exerts a protective role in murine experimental glomerulonephritis.2015
- Author(s)
  Hamour, S., Gan, P. Y., Pepper, R., Florez Barros, F., Wang, H. H., O'Sullivan, K., Iwakura, Y., Cook, T., Pusey, C., Holdsworth, S., and Salama, A.
- Journal Title
  
  PLoS One
  
  Volume: 10
- DOI
  10.1371/journal.pone.0136238
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011
[Journal Article] Multiple CD11c+ cells collaboratively express IL-1β to modulate stromal vascular endothelial growth factor and lymph node vascular-stromal growth.2014
- Author(s)
  Benahmed, F., Chyou, S., Dasoveanu, D., Chen, J., Kumar, V., Iwakura, Y., and Lu, T. T.
- Journal Title
  
  J. Immunol.
  
  Volume: 192(9) Pages: 4153-4163
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] NF-kB/TNF-a positive feedback loop with active proteasome machinery supports myeloid leukemia initiating cell capacity.2014
- Author(s)
  Kagoya Y, Yoshimi A, Kataoka K, Nakagawa M, Kumano K, Arai S, Kobayashi H, Saito T, Iwakura Y, Kurokawa M.
- Journal Title
  
  Journal of Clinical Investigation
  
  Volume: 124 Pages: 528-42
- DOI
  10.1172/jci68101
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23591369, KAKENHI-PROJECT-23689065, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-24249055, KAKENHI-PROJECT-24790964, KAKENHI-PROJECT-25293316, KAKENHI-PROJECT-25462359, KAKENHI-PROJECT-25670445, KAKENHI-PROJECT-26293330, KAKENHI-PROJECT-26461170, KAKENHI-PROJECT-26860474
[Journal Article] Involvement of IL-17A-induced hypercontractility of intestinal smooth muscle cells in persistent gut moter dysfunction.2014
- Author(s)
  Akiho, H., Tokita, Y., Nakamura, K., Satoh, K., Nishiyama, M., Tsuchiya, N., Tsuchiya, K., Ohbuchi, K., Iwakura, Y., Ihara, E., Takayanagi, R., and Yamamoto, M.
- Journal Title
  
  PLoS One
  
  Volume: 9(5)
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] The role of C-type lectin receptors in host defense against microbial pathogens.2014
- Author(s)
  Yabe R, Iwakura Y, Saijo S.
- Journal Title
  
  “Glycoscinece: Biology and Medicine”
  
  Volume: 1 Pages: 1-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293094
[Journal Article] Recognition of tumor cells by Dectin-1 orchestrates innate immune cells for anti-tumor responses.2014
- Author(s)
  Chiba, S., Ikushima, H., Ueki, H., Yanai, H., Kimura, Y., Hangai, S., Nishio, J., Negishi, H., Tamura, T., Saijo, S., Iwakura, Y., and Taniguchi T.
- Journal Title
  
  Elife
  
  Volume: 3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] The role of C-type lectin receptors in host defense against microbial pathogens.2014
- Author(s)
  Yabe, R., Iwakura, Y., and Saijo, S.
- Journal Title
  
  Glycoscinece: Biology and Medicine
  
  Volume: - Pages: 1319-1329
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] Ectopic cerebellar cell migration causes maldevelopment of purkinje cells and abnormal motor behavior in CXCR4 null mice.2014
- Author(s)
  Huang, G. J., Edwards, A., Tsai, C. Y., Lee, Y. S., Peng, L., Era, T., Hirabayashi, Y., Tsai, C. Y., Nishikawa, S., Iwakura, Y., Chen, S. J., and Flint, J.
- Journal Title
  
  PLoS One
  
  Volume: 8
- DOI
  10.1371/journal.pone.0086471
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] Defect of CARD9 leads to impaired accululation of IFN-g-producing memory-phenotype T cells in lungs and increased susceptibility to pulmonary infection with Cryptococcus neoformans.2014
- Author(s)
  Yamamoto, H., Nakamura, Y., Sato, K., Takahashi, Y., Nomura, T., Miyasaka, T., Ishii, K., Hara, H., Yamamoto, N., Kanno, E., Iwakura, Y., and Kawakami, K.
- Journal Title
  
  Infect. Immun.
  
  Volume: 82(4) Pages: 1606-1615
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] Stage-specific roles for Cxcr4 signaling in murine hematopoietic stem/progenitor cells in the process of bone marrow repopulation.2014
- Author(s)
  Lai, C. Y., Yamazaki, S., Okabe, M., Suzuki, S., Maeyama, Y., Iimura, Y., Onodera. M., Kakuta, S., Iwakura, Y., Nojima, M., Otsu, M., and Nakauchi, H.
- Journal Title
  
  Stem Cells
  
  Volume: 32(7) Pages: 1929-1942
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] Rag2-deficient IL-1 receptor antagonist deficient mice are a novel colitis model in which innate lymphoid cell-derived IL-17 is involved in the pathogenesis.2014
- Author(s)
  Akitsu A., Kakuta S., Saijo S., Iwakura Y.
- Journal Title
  
  Exp. Anim.
  
  Volume: 印刷中
- NAID
  130003391627
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] Inflammasome-independent IL-1b mediates autoinflammatory diseases in Pstpip2-deficient mice.2014
- Author(s)
  Cassel, S. L., Janczy, J. R., Bing, X., Wilson, S. P., Olivier, A. K., Otero, J. E., Iwakura, Y., Shayakhmetov, D. M., Bassuk, A. G., Abu-Amer, Y., Brogden, K. A., Burns, T. L., Sutterwala, F. S., and Ferguson, P. J.
- Journal Title
  
  Proc. Natl. Acad. Sci. U. S. A.
  
  Volume: 111 Pages: 1072-1077
- DOI
  10.1073/pnas.1318685111
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] Mast cell-derived IL-1β contributes to uric acid crystal-induced acute arthritis in mice.2014
- Author(s)
  Reber, L. L., Marichal, T., Sokolove, J., Starkl, P., Gaudenzio, N., Iwakura, Y., Karasuyama, H., Schwartz, L. B., Robinson, W. H., Tsai, M., and Galli, S. J.
- Journal Title
  
  Arthritis Rheumatol.,
  
  Volume: 66(10) Pages: 2881-2891
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] Rag2-deficient IL-1 receptor antagonist-deficient mice are a novel colitis model in which innate lymphoid cell-derived IL-17 is involved in the pathogenesis.2014
- Author(s)
  Akitsu, A., Kakuta, S., Saijo, S., and Iwakura, Y.
- Journal Title
  
  Exp. Anim.
  
  Volume: 63(2) Pages: 235-246
- NAID
  130003391627
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] Persistent release of IL-1s from skin is associated with systemic cardio-vascular disease. Emaciation and systemic amyloidosis: the potential of anti-IL-1 therapy for systemic inflammatory disease.2014
- Author(s)
  Yamanaka, K., Nakanishim, T., Saito, H., Maruyamam, J., Isoda, K., Yokochi, A., Imanaka-Yoshida, K., Tsuda, K., Kakeda, M., Okamoto, R., Fujita, S., Iwakura, Y., Suzuki, N., Ito, M., Maruyama, K., Gabazza, E. C., Yoshida, T., Shimaoka, M., and Mizutani, H.
- Journal Title
  
  PLoS One
  
  Volume: 9（8）
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] Immune complexes inhibit IL-1 secretion and inflammasome activation.2014
- Author(s)
  Janczy, J. R., Ciraci, C., Haasken, S., Iwakura, Y., Olivier, A. K., Cassel, S. L., and Sutterwala, F. S.
- Journal Title
  
  J. Immunol.,
  
  Volume: 193(10) Pages: 5190-5198
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] Dectin-2 promotes house dust mite-induced Th2 and Th17 cell differentiation and allergic airway inflammation in mice2014
- Author(s)
  Norimoto, A., Hirose, K., Iwata, A., Tamachi, T., Yokota, M., Takahashi, K., Saijo, S., Iwakura, Y., and Nakajima, H.
- Journal Title
  
  Am J Respir Cell Mol Biol.
  
  Volume: 印刷中 Pages: 201-209
- DOI
  10.1165/rcmb.2013-0522oc
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-26461184, KAKENHI-PROJECT-26860598
[Journal Article] Intrahepatic innate lymphoid cells secrete IL-17A and IL-17F that are crucial for T cell priming in vial infection.2014
- Author(s)
  Jie, Z., Liang, Y., Hou, L., Dong, C., Iwakura, Y., Soong, L., Cong, Y., and Sun, J.
- Journal Title
  
  J. Immunol.
  
  Volume: 192 Pages: 3289-3300
- DOI
  10.4049/jimmunol.1303281
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] NLRP3 regulates neutrophil functions and contributes to hepatic ischemia-reperfusion injury independently of inflammasomes.2014
- Author(s)
  Inoue, Y., Shirasuna, K., Kimura, H., Usui, F., Kawashima, A., Karasawa, T., Tago, K., Dezaki, K., Nishimura, S., Sagara, J., Noda, T., Iwakura, Y., Tsutsui, H., Taniguchi, S., Yanagisawa, K., Yada, T., Yasuda, Y., and Takahashi, M.
- Journal Title
  
  J. Immunol.
  
  Volume: 192(9) Pages: 4342-4351
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] Rag2-deficient IL-1 Receptor Antagonist-deficient Mice Are a Novel Colitis Model in Which Innate Lymphoid Cell-derived IL-17 Is Involved in the Pathogenesis.2014
- Author(s)
  Akitsu A, Kakuta S, Saijo S, Iwakura Y.
- Journal Title
  
  Exp Anim.
  
  Volume: 63 Pages: 235-246
- NAID
  130003391627
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23390101
[Journal Article] Targeting IL-1b and IL-17A driven inflammation during influenza-induced exacerbations of chronic lung inflammation.2014
- Author(s)
  Sichelstiel, A., Yadava, K., Trompette, A., Salami, O., Iwakura, Y., Nicod, L. P., and Marsland, B. J.
- Journal Title
  
  PLoS One
  
  Volume: 9(2)
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] A non-agonistic Dectin-1 ligand transforms CpG into a multitask nano-particulate TLR9 agonist.2014
- Author(s)
  Kobiyama K, Aoshi T, Narita H, Kuroda E, Hayashi M, Tetsutani K, Koyama S, Mochizuki S, Sakurai K, Katakai Y, Yasutomi Y, Saijo S, Iwakura Y, Akira S, Coban C, Ishii KJ.
- Journal Title
  
  Proc.Natl.Acad Sci.
  
  Volume: 111 Pages: 3086-3091
- DOI
  10.1073/pnas.1319268111
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390101, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-24591145, KAKENHI-PROJECT-25293100, KAKENHI-PROJECT-25670225
[Journal Article] Dectin-2 regulates the effector phase of house dust mite-elicited pulmonary inflammation independently from its role in sensitization.2014
- Author(s)
  Parsons MW, Li L, Wallace AM, Lee MJ, Katz HR, Fernandez JM, Saijo S, Iwakura Y, Austen KF, Kanaoka Y, Barrett NA.
- Journal Title
  
  J. Immunol.
  
  Volume: 192 Pages: 1361-1371
- DOI
  10.4049/jimmunol.1301809
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390101, KAKENHI-PROJECT-24220011
[Journal Article] Excess IL-1 signaling enhances the development of Th17 cells by downregulating TGF-b-induced Foxp3 expression.2014
- Author(s)
  Ikeda S, Saijo S, Murayama MA, Shimizu K, Akitsu A, Iwakura Y.
- Journal Title
  
  J. Immunol.
  
  Volume: 192 Pages: 1449-1458
- DOI
  10.4049/jimmunol.1300387
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390101, KAKENHI-PROJECT-24220011
[Journal Article] Exacerbation of experimental autoimmune encephalomyelitis in mice deficient for DCIR, an inhibitory C-type lectin receptor2014
- Author(s)
  Seno A, Maruhashi T, Kaifu T, Yabe R, Fujikado N, Ma G, Ikarashi T, Kakuta S, Iwakura Y
- Journal Title
  
  Experimental Animals
  
  Volume: Epub
- NAID
  130005069862
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26430095
[Journal Article] Rag2-deficient IL-1 Receptor Antagonist-deficient Mice Are a Novel Colitis Model in Which Innate Lymphoid Cell-derived IL-17 Is Involved in the Pathogenesis.2014
- Author(s)
  Akitsu A, Kakuta S, Saijo S, Iwakura Y.
- Journal Title
  
  Exp Anim.
  
  Volume: 63 Pages: 235-246
- NAID
  130003391627
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293094
[Journal Article] CTRP3 plays an important role in the development of collagen-induced arthritis in mice.2014
- Author(s)
  Murayama MA, Kakuta S, Maruhashi T, Shimizu K, Seno A, Kubo S, Sato N, Saijo S, Hattori M, Iwakura Y.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 443 Pages: 42-48
- DOI
  10.1016/j.bbrc.2013.11.040
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390101, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-24500488
[Journal Article] Mechanism of pro-tumorigenic effect of BMP-6: Neovascularizatioon involving tumor-associated macrophages and IL-1a.2014
- Author(s)
  Kwon, S. J., Lee, G. T., Lee, J. H., Iwakura, Y., Kim, W. J., and Kim, I. Y.
- Journal Title
  
  Prostate
  
  Volume: 74 Pages: 121-133
- DOI
  10.1002/pros.22734
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] Dectin-2 promotes house dust mite-induced T helper type 2 and type 17 cell differentiation and allergic airway inflammation in mice.2014
- Author(s)
  Norimoto A, Hirose K, Iwata A, Tamachi T, Yokota M, Takahashi K, Saijo S, Iwakura Y, Nakajima H.
- Journal Title
  
  Am J Respir Cell Mol Biol.
  
  Volume: 51(2) Pages: 201-209
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] Gene targeting study reveals unexpected expression of brain expressed X-linked 2 in endocrine and tissue stem/progenitor cells in mice.2014
- Author(s)
  Ito, K., Yamazaki, S., Yamamoto, R., Tajima, Y., Yanagida, A., Kobayashi, T., Kato-Itoh, M., Kakuta, S., Iwakura, Y., Nakauchi, H., and Kamiya, A.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 289(43) Pages: 29892-29911
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] Dectin-2 promotes house dust mite-induced T helper type 2 and type 17 cell differentiation and allergic airway inflammation in mice.2014
- Author(s)
  Chiba S, Ikushima H, Ueki H, Yanai H, Kimura Y, Hangai S, Nishio J, Negishi H, Tamura T, Saijo S, Iwakura Y, Taniguchi T.
- Journal Title
  
  Am J Respir Cell Mol Biol.
  
  Volume: 04177 Pages: 04177-04177
- DOI
  10.7554/elife.04177
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-12J04120, KAKENHI-PROJECT-13J05883, KAKENHI-PROJECT-14F04416, KAKENHI-PROJECT-14J04316, KAKENHI-PROJECT-14J12292, KAKENHI-PLANNED-22114007, KAKENHI-PROJECT-23390101, KAKENHI-PROJECT-24590574, KAKENHI-PROJECT-26293094, KAKENHI-PROJECT-26860316
[Journal Article] Perivascular leukocyte clusters are essential for efficient activation of effector T cells in the skin.2014
- Author(s)
  Natsuaki, Y., Egawa, G., Nakamizo, S., Ono, S., Hanakawa, S., Okada, T., Kusuba, N., Otsuka, A., Kitoh, A., Honda, T., Nakajima, S., Tsuchiya, S., Sugimoto, Y., Ishii, K. J , Tsutsui, H., Yagita, H., Iwakura, Y., Kubo, M., Ng, L. G., Hashimoto, T., Fuentes, J., Guttman-Yassky, E., Miyachi, Y., and Kabashima, K.
- Journal Title
  
  Nat. Immunol.
  
  Volume: 15（11） Pages: 1064-1069
- NAID
  120005477231
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] Interleukin-1 receptor antagonist originating from bone marrow-derived cells and non-bone marrow-derived cells helps to suppress arterial inflammation and reduce neointimal formation after injury.2014
- Author(s)
  Isoda, K., Akita, K., Isobe, S., Niida, T., Adachi, T., Iwakura, Y., and Daida, H.
- Journal Title
  
  J. Atheroscler. Thromb.
  
  Volume: 21（11） Pages: 1208-1218
- NAID
  130004690941
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] Cardiac fibroblasts mediate IL-17A-driven inflammatory dilated cardiomyopathy.2014
- Author(s)
  Wu, L., Ong, S., Talor, M. V., Barin, J. G., Baldeviano, G.　C, Kass,D.A., Bedja, D., Zhang, H., Sheikhm, A., Margolick, J. B., Iwakura, Y., Rose, N. R., and Cihakova, D.
- Journal Title
  
  J. Exp. Med.
  
  Volume: 211(7) Pages: 1449-1464
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] Potential role of myeloid cell/eosinophil-derived IL-17 in LPS-induced endotoxin shock.2014
- Author(s)
  Shimura, E., Shibui, A., Narushima, S., Nambu, A., Yamaguchi, S., Akitsu, A., Leonard, W. J., Iwakura, Y., Matsumoto, K., Suto, H., Okumura, K., Sudo, K., and Nakae, S.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 453(1) Pages: 1-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] An ITAM-Syk-CARD9 signaling axis triggers contact hypersensitivity by stimulating IL-1 production in dendritic cells.2014
- Author(s)
  Yasukawa, S., Miyazaki, Y., Yoshii, C., Nakaya, M., Ozaki, N., Toda, S., Kuroda, E., Ishibashi, K., Yasuda, T., Natsuaki, Y., Mi-Ichi, F., Iizasa, E., Nakahara, T., Yamazaki, M., Kabashima, K., Iwakura, Y., Takai, T., Saito, T., Kurosaki, T., Malissen, B., Ohno, N., Furue, M., Yoshida, H., and Hara, H.
- Journal Title
  
  Nat. Commun.,
  
  Volume: 5 Pages: 3755-3755
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] Cigarette smoke primes the pulmonary environment to IL-1α/CXCR-2-dependent nontypeable haemophilus influenzae-exacerbated neutrophillia in mice.2014
- Author(s)
  Nikota, J. K., Shen, P., Morissette, M. C., Fernandes, K., Roos, A., Chu, D. K., Barra, N. G., Iwakura, Y., Kolbeck, R., Humbles, A. A., and Stampfli, M. R.
- Journal Title
  
  J. Immunol.
  
  Volume: 193(6) Pages: 3134-3145
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] Dectin-2 promotes house dust mite-induced Th2 and Th17 cell differentiation and allergic airway inflammation in mice.2014
- Author(s)
  Norimoto A, Hirose K, Iwata A, Tamachi T, Yokota M, Takahashi K, Saijo S, Iwakura Y, Nakajima H.
- Journal Title
  
  Am J Respir Cell Mol Biol.
  
  Volume: Epub ahead of print
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390101
[Journal Article] Critical role for inflammasome-independent IL-1b production in osteomyelitis.2014
- Author(s)
  Lukens, J. R., Gross, J. M., Calabrese, C., Iwakura, Y., Lamkanfi, M., Vogel, P., and Kanneganti, T. D.
- Journal Title
  
  Proc. Natl. Acad. Sci. U. S. A.
  
  Volume: 111 Pages: 1066-1071
- DOI
  10.1073/pnas.1318688111
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] Intrahepatic innate lymphoid cells secrete IL-17A and IL-17F that are crucial for T cell priming in vial infection.2014
- Author(s)
  .Jie, Z., Liang, Y., Hou, L., Dong, C., Iwakura, Y., Soong, L., Cong, Y., and Sun, J.
- Journal Title
  
  J. Immunol.
  
  Volume: 192(7) Pages: 3289-3300
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] Multiple CD11c+ cells collaboratively express IL-1b to modulate stromal vascular endothelial growth factor and lymph node vascular-stromal growth.2014
- Author(s)
  Benahmed, F., Chyou, S., Dasoveanu, D., Chen, J., Kumar, V., Iwakura, Y., and Lu, T. T.
- Journal Title
  
  J. Immunol.
  
  Volume: 印刷中
- DOI
  10.4049/jimmunol.1301765
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] IL-17A as an inducer for Th2 immune responses in murine atopic dermatitits models.2014
- Author(s)
  Nakajima, S., Kitoh, A., Egawa, G., Natsuaki, Y., Nakamizo, S., Sagita, Moniaga, C., Otsuka, A., Honda, T., Hanakawa, S., Amano, W., Iwakura, Y., Nakae, S., Kubo, M., Miyachi, Y., and Kabashima, K.
- Journal Title
  
  J. Invest. Dermatol.
  
  Volume: 134(8) Pages: 2122-2130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] Chemokine receptor CCR8 is required for lipopolysassharide-triggered cytokine production in mouse peritoneal macrophages.2014
- Author(s)
  Oshio, T., Kawashima, R., Kawamura, Y. I., Hagiwara, T., Mizutani, N., Okada, T., Otsubo, T., Inagaki-Ohara, K., Matsukawa, A., Haga, T., Kakuta, S., Iwakura, Y., Hosokawa, S., and Dohi, T.
- Journal Title
  
  PLoS One
  
  Volume: 9(4)
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] Alterations in the microbiota drive interleukin-17C production from intestinal epithelial cells to promote tumorigenesis.2014
- Author(s)
  Song, X., Gao, H., Lin, Y., Yao, Y,. Zhu S, Wang J, Liu Y, Yao X, Meng G, Shen N, Shi Y, Iwakura Y, and Qian Y.
- Journal Title
  
  Immunity
  
  Volume: 40(1) Pages: 140-152
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] Involvement of Gr-1dull+ cellsin the production of TNF-a and IL-17 and exacerbated systemic inflammatory response caused by lipopolysaccharide.2014
- Author(s)
  Tanno, D., Akahori, Y., Toyama, M., Sato, K., Kudo, D., Abe, Y., Miyasaka, T., Yamamoto, H., Ishii, K., Kanno, E., Maruyama, R., Kushimoto, S., Iwakura, Y., and Kawakami, K.
- Journal Title
  
  Inflammation
  
  Volume: 37 Pages: 186-195
- DOI
  10.1007/s10753-013-9729-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] IL-22+CD4+T細胞による大腸炎誘導と抑制．2013
- Author(s)
  角木基彦、岩倉洋一郎
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 59 Pages: 405-410
- NAID
  40019636556
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] IL-17A mediates early post-translpant lesions agter teterotopic trachea allotransplantation in mice.2013
- Author(s)
  Lemaitre, P. H., Vokaer, B., Charbonnier, L. M., Iwakura, Y., Estenne, M., Goldman, M., Leo, O., Remmelink, M., and Le Moine, A.
- Journal Title
  
  PLoS One
  
  Volume: 8
- DOI
  10.1371/journal.pone.0070236
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] C-Type Lectin MCL Is an FcR<gamma>-Coupled Receptor that Mediates the Adjuvanticity of Mycobacterial Cord Factor2013
- Author(s)
  Miyake Y, Ynmasaki S, et al.
- Journal Title
  
  Immunity
  
  Volume: 38 Pages: 1050-1062
- DOI
  10.1016/j.immuni.2013.03.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11F01107, KAKENHI-PROJECT-22590875, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-24500488, KAKENHI-PROJECT-24791552, KAKENHI-PROJECT-25461178, KAKENHI-PUBLICLY-23114504
[Journal Article] RIP1-driven autoinflammation targets IL-1a independently of inflammasomes and RIP3.2013
- Author(s)
  Lukens, J. R., Vogel, P., Johnson, G. R., Kelliher, M. A., Iwakura, Y., Lamkanfi, M., and Kanneganti, T. D.
- Journal Title
  
  Nature
  
  Volume: 498 Pages: 224-227
- DOI
  10.1038/nature12174
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] Obesity-induced gut microbial metabolite prootes liver cancer through senescence secretome.2013
- Author(s)
  Yoshimoto, S., Loo, T. M., Atarashi, K., Kanda, H., Sato, S., Oyadomari, S., Iwakura, Y., Oshima, K., Morita, H., Hattori, M., Honda, K., Ishikawa, Y., Hara, E., and Ohtani, N.
- Journal Title
  
  Nature
  
  Volume: 499 Pages: 97-101
- DOI
  10.1038/nature13004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] Pam3CSK4 enhanced beta cell loss and diabetogenesis: The roles of IFN-gamma and IL-17.2013
- Author(s)
  Al Shamsi, M., Shahin, A., Iwakura, Y., Lukic, M. L., and Mensah-Brown, E. P.
- Journal Title
  
  Clin. Immunol.
  
  Volume: 149 Pages: 86-96
- DOI
  10.1016/j.clim.2013.06.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] 遺伝子改変マウスによる疾患発症機構の解析．2013
- Author(s)
  岩倉洋一郎
- Journal Title
  
  感染・炎症・免疫
  
  Volume: 43 Pages: 313-319
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] Interleukin-1b induced by Helicobacter pylori infection enhances mouse gastric carcinogenesis.2013
- Author(s)
  Shigematsu, Y., Niwa, T., Rehnberg, E., Toyoda, T., Yoshida, S., Mori, A., Wakabayashi, M., Iwakura, Y., Ichinose, M., Kim, Y. J., and Ushijima, T.
- Journal Title
  
  Cancer Lett.
  
  Volume: 340 Pages: 141-147
- DOI
  10.1016/j.canlet.2013.07.034
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] Visceral Adipose Tissue-derived Serine Proteinase Inhibitor Inhibits Apoptosis of Endothelial Cells as a Ligand for the Cell-Surface GRP78/Voltage-dependent Anion Channel Complex2013
- Author(s)
  Nakatsuka A
- Journal Title
  
  Circ Res.
  
  Volume: 112(5) Pages: 771-780
- DOI
  10.1161/circresaha.111.300049
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249053, KAKENHI-PROJECT-23390241, KAKENHI-PROJECT-23659470, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-24500488, KAKENHI-PROJECT-24790926, KAKENHI-PUBLICLY-23114504, KAKENHI-PUBLICLY-23126516
[Journal Article] Dectin-2-dependent NKT cell activation and serotype-specific antibody production in mice immunized with pneumococcal polysaccharide vaccine.2013
- Author(s)
  Miyasaka T, Akahori Y, Toyama M, Miyamura N, Ishii K, Saijo S, Iwakura Y, Kinjo Y, Miyazaki Y, Oishi K, Kawakami K.
- Journal Title
  
  PLoS One
  
  Volume: 8
- DOI
  10.1371/journal.pone.0078611
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390101, KAKENHI-PROJECT-24220011
[Journal Article] Interleukin-17-producing innate lymphoid cells and the NLRP3 inflammasome facilliate obesity-associated airway hyperreactivity.2013
- Author(s)
  Kim, H. Y., Lee, H. J., Chang, Y. J., Pichavant, M., Shore, S. A., Fitzgerald, K. A., Iwakura, Y., Israel, E., Bolger, K., Faul, J., Dekruyff, R. H., and Umetsu, D. T.
- Journal Title
  
  Nat. Med.
  
  Volume: 20 Pages: 54-61
- DOI
  10.1038/nm.3423
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] The Arf GAP SMAP2 is necessary for organized vesicle budding from the Trans-Golgi-network and subsequent acrosome formation in spermiogenesis.2013
- Author(s)
  Funaki T, Kon S, Tanabe K, Natsume W, Sato S, Shimizu T, Yoshida N, Wong WF, Ogura A, Ogawa T, Inoue K, Ogonuki N, Miki H, Mochida K, Endoh K, Yomogida K, Fukumoto M, Horai R, Iwakura Y, Ito C, Toshimori K, Watanabe T, Satake M.
- Journal Title
  
  Molecular Biology of the Cel
  
  Volume: 24 Pages: 2633-2644
- DOI
  10.1091/mbc.e13-05-0234
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23113721, KAKENHI-PROJECT-23501256, KAKENHI-PROJECT-23770148, KAKENHI-PUBLICLY-24112706, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-24570159, KAKENHI-PROJECT-24592441, KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-25293041, KAKENHI-PROJECT-25670087
[Journal Article] Negative feedback on IL-23 exerted by IL-17A during pulmonary inflammation.2013
- Author(s)
  Silverpil, E., Wright, A. K., Hansson, M., Jirholt, P., Henningsson, L., Smith, M. E., Gordon, S. B., Iwakura, Y., Gjertsson, I., Glader, P., and Linden, A.
- Journal Title
  
  Innate Immun.
  
  Volume: 19 Pages: 479-492
- DOI
  10.1177/1753425912470470
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] Neutrophils are essential as a source of IL-17 in the effector phase of arthritis.2013
- Author(s)
  Katayama, M., Ohmura, K., Yukawa, N., Terao, C., Hashimoto, M., Yoshifuji, H., Kawabata, D., Fujii, T., Iwakura, Y., and Mimori, T.
- Journal Title
  
  PLoS One
  
  Volume: 8
- DOI
  10.1371/annotation/5fedb3bf-c9c2-4862-9ad5-23c8ae484ad5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] Chronic follicular bronchiolitis requires antigen-specific regulatory T cell control to prevent fatal disease progression.2013
- Author(s)
  Schmitt, E. G., Haribhai, D., Jeschke, J. C., Co, D. O., Ziegelbauer, J., Yan, K., Iwakura, Y., Mishra, M. K., Simpson, P., Salzman, N. H., and Williams, C. B.
- Journal Title
  
  J. Immunol.
  
  Volume: 191 Pages: 5460-5476
- DOI
  10.4049/jimmunol.1301576
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] Double deficiency in IL-17 and IFN-γ signalling significantly suppresses the development of diabetes in the NOD mouse2013
- Author(s)
  Kuriya G, Uchida T, Akazawa S, Kobayashi M, Nakamura K, Satoh T, Horie I, Kawasaki E, Yamasaki H, Yu L, Iwakura Y, Sasaki H, Nagayama Y, Kawakami A, Abiru N.
- Journal Title
  
  Diabetologia
  
  Volume: 56 Pages: 1773-1780
- DOI
  10.1007/s00125-013-2935-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791060, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-24591334
[Journal Article] Hypoxia enhances innate immune activation to Aspergillus fumigatus through cell wall modulation.2013
- Author(s)
  Shepardson, K. M., Ngo, L. Y., Aimanianda, V., Latge, J.-P., Barker, B. M., Blosser, S. J., Iwakura, Y., Hohl, T. M., and Cramer, R. A.
- Journal Title
  
  Microbe. Infect.
  
  Volume: 15 Pages: 259-269
- DOI
  10.1016/j.micinf.2012.11.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] Generation of a mouse model with down-regulated U50 snoRNA (SNORD50) expression and its organ-specific phenotypic modulation.2013
- Author(s)
  Soeno Y, Fujita K, Kudo T, Asagiri M, Kakuta S, Taya Y, Shimazu Y, Sato K, Tanaka-Fujita R, Kubo S, Iwakura Y, Nakamura Y, Mori S, and Aoba T
- Journal Title
  
  PLoS One
  
  Volume: 8
- DOI
  10.1371/journal.pone.0072105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592716, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-24500488, KAKENHI-PROJECT-24592780, KAKENHI-PROJECT-24659822, KAKENHI-PROJECT-24689056, KAKENHI-PROJECT-25462935, KAKENHI-PROJECT-25463154
[Journal Article] Fatty acid-inudced mitochondrial uncoupling elicits inflammasome-independent IL-1a and sterile vascular inflammation in atherosclerosis.2013
- Author(s)
  Freigang, S., Ampenberger, F., Weiss, A., Kanneganti, T. D., Iwakura, Y., Hersberger, M., and Kopf, M.
- Journal Title
  
  Nat. Immunol.
  
  Volume: 14 Pages: 1045-1053
- DOI
  10.1038/ni.2704
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] Regulatory T cells are strong promoters of acute ischemia stroke in mice by inducing dysfunction of the cerebral microvasculature.2013
- Author(s)
  Kleinschnitz, C., Kraft, P., Dreykluft, A., Hagedorn, I., Gobel, K., Schuhmann, M. K., Langhauser, F., Helluy, X., Schwarz, T., Bittner, S., Mayer, C. T., Brede, M., Varallyay. C., Pham, M., Bendszus, M., Jakob, P., Magnus, T., Meuth, S. G., Iwakura, Y., Zernecke, A. et al.
- Journal Title
  
  Blood
  
  Volume: 121 Pages: 679-691
- DOI
  10.1182/blood-2012-04-426734
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] Colitogenic effector T cells: roles of gut-homing integrin, gut antigen specificity and gd T cells.2013
- Author(s)
  Do, J. S., Visperas, A., Freeman, M. L., Iwakura, Y., Oukka, M., and Min, B.
- Journal Title
  
  Immunol. Cell Biol.
  
  Volume: 92 Pages: 90-98
- DOI
  10.1038/icb.2013.70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] IL-23 protection against Plasmodium berghei infection in mice is partially dependent on IL-17 from macrophages.2013
- Author(s)
  Ishida H, Imai T, Suzue K, Hirai M, Taniguchi T, Yoshimura A, Iwakura Y, Okada H, Suzuki T, Shimokawa C, and Hisaeda
- Journal Title
  
  European journal of immunology
  
  Volume: 43 Pages: 2696-2706
- DOI
  10.1002/eji.201343493
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24117504, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-24590501, KAKENHI-PROJECT-24790399, KAKENHI-PROJECT-25670226
[Journal Article] Cyclosporine A drives a Th17- and Th2-mediated posttransplant obliterative airway disease.2013
- Author(s)
  Lemaitre, P. H., Vokaer, B., Charbonnier, L. M., Iwakura, Y., Field, K. A., Estenne, M., Goldman, M., Leo, O., Remmelink, M., and Le Moine, A.
- Journal Title
  
  Am. J. Transplant.
  
  Volume: 13 Pages: 611-620
- DOI
  10.1111/ajt.12067
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] IL-17A is essential to the development of elastase-induced pulmonary inflammation and emphysema in mice.2013
- Author(s)
  Etsuko Kurimoto
- Journal Title
  
  Respir Res.
  
  Volume: 14 Pages: 5-5
- DOI
  10.1186/1465-9921-14-5
- NAID
  120005425640
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590526, KAKENHI-PROJECT-22591092, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-25860644
[Journal Article] IL-17A promotes macrophage effector mechanisms against Trypanosoma cruzi by trapping parasites in the endolysosomal compartment.2013
- Author(s)
  Erdmann, H., RoBnagel, C., Bohme, J., Iwakura, Y., Jacobs, T., Schaible, U. E., and Holscher, C.
- Journal Title
  
  Immunobiology
  
  Volume: 218, Pages: 910-923
- DOI
  10.1016/j.imbio.2012.10.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] Evaluation of Kampo medicines used to treat rheumatoid arthritis in collagen-induced arthritic and pX transgenic mice.2013
- Author(s)
  Ono, Y., Ogihara, Y., Saijo, S., Iwakura, Y., and Inoue, M.
- Journal Title
  
  Mod. Rheumatol.
  
  Volume: 13 Pages: 50-56
- DOI
  10.3109/s101650300007
- NAID
  10015486726
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] Genetic deletion of IL-17A reduces cigarette smoke-induced inflammation and alveolar type II cell apoptosis.2013
- Author(s)
  Chang, Y., Al-Alwan, L., Audusseau, S., Chouiali, F., Carlevaro-Fita, J., Iwakura, Y., Baglole, C. J., Eidelman, D. H., and Hamid, Q.
- Journal Title
  
  Am. J. Physiol. Lung Cell Mol. Physiol.
  
  Volume: 306
- DOI
  10.1152/ajplung.00111.2013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] Transgenic expression of the human LEDGF/p75 gene relieves the species barrier against HIV-1 infecion in mouse cells.2013
- Author(s)
  Tada, T., Kadoki, M., Yang, L., Tokunaga, K. and Iwakura, Y.
- Journal Title
  
  Frontiers in Microbiology
  
  Volume: 4 Pages: 377-377
- DOI
  10.3389/fmicb.2013.00377
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-24790992
[Journal Article] SMAP1 deficiency perturbs receptor trafficking and predisposes mice to myelodysplasia．2013
- Author(s)
  Kon et al.
- Journal Title
  
  J Clin Invest
  
  Volume: 123 Pages: 1123-1137
- DOI
  10.1172/jci63711
- NAID
  40019856266
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501256, KAKENHI-PROJECT-23770137, KAKENHI-PROJECT-23770148, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-24591404, KAKENHI-PROJECT-24659458
[Journal Article] Mature dendritic cell suppression by IL-1 receptor antagonist on retinal pigment epithelium cells.2013
- Author(s)
  Sugita S, Kawazoe Y, Imai A, Usui Y, Iwakura Y, Isoda K, Ito M, Mochizuki M
- Journal Title
  
  Invest. Ophthalmol. Vis. Sci.
  
  Volume: 54巻 Pages: 3240-3249
- DOI
  10.1167/iovs.12-11483
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591957, KAKENHI-PROJECT-24220011
[Journal Article] MFGE8 inhibits inflammasome-induced IL-1b production and limits postischemic cerebral injury.2013
- Author(s)
  Deroide, N., Li, X., Lerouet, D., Van Vre, E., Baker, L., Harrison, J., Poittevin, M. Masters, L., Nih, L., Margaill, I., Iwakura, Y., Ryffel, B., Pocard, M., Tedgui, A., Kubis, N., and Mallat, Z.
- Journal Title
  
  J. Clin. Invest.
  
  Volume: 123 Pages: 1176-1181
- DOI
  10.1172/jci65167
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24220011
[Journal Article] G. Dectin-1 diversifies Aspergillus fumigatus-specific T cell responses by inhibiting T helper type 1 CD4 T cell differentiation2011
- Author(s)
  Rivera, A., Hohl, T. M., Collins, N., Leiner, I., Gallegos, A., Saijo, S., Coward, J. W., Iwakura, Y., and Pamer, E.
- Journal Title
  
  J. Exp. Med.
  
  Volume: 208 Pages: 369-381
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Functional specialization of interleukin-17 family members2011
- Author(s)
  Iwakura, Y.
- Journal Title
  
  Immunity
  
  Volume: 34 Pages: 149-62
- DOI
  10.1016/j.immuni.2011.02.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390101, KAKENHI-PROJECT-21390303
[Journal Article] Functional recovery after peripheral nerve injury is dependent on the proinflammatory cytokines IL-1. and TNF : implicaitons for neuropathic pain2011
- Author(s)
  Nadeau, S., Filali, M., Zhang, J., Kerr, B. J., Rivest, S., Soulet, D., Iwakura, Y., de Rivero Vaccari, J. P., Keane, R. W., and Lacroix, S.
- Journal Title
  
  J. Neurosci.
  
  Volume: 31 Pages: 12533-12542
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Dectin-1 and Dectin-2 in innate immunity against fungi2011
- Author(s)
  Saijo, S., and Iwakura, Y.
- Journal Title
  
  Int. Immunol.
  
  Volume: 23 Pages: 467-472
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Desmoglein 3-specific CD4+T cells induce pemphigus vulgaris and interface dermatitis in mice2011
- Author(s)
  Takahashi, H., Kouno, M., Nagao, K., Wada, N., Hata, T., Nishimoto, S., Iwakura, Y., Yoshimura, A., Yamada, T., Kuwana, M., Fujii, H., Koyasu, S., and Amagai, M.
- Journal Title
  
  J. Clin. Invest.
  
  Volume: 121 Pages: 3677-3688
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Control of T(H) 17 cells occurs in the small intestine2011
- Author(s)
  Esplugues, E., Huber, S., Gagliani, N., Hauser, A. E., Town, T., Wan, Y. Y., O' Connor, W., Rongvaux, A., Van Rooijen, N., Haberman, A. M., Iwakura, Y., Kuchroo, V. K., Kolls, J. K., Bluestone, J. A., Herold, K. C., and Flavell, R. A.
- Journal Title
  
  Nature
  
  Volume: 475 Pages: 514-518
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Functional specialization of IL-17 family members2011
- Author(s)
  Iwakura, Y., Ishigame, H., Saijo, S., and Nakae, S.
- Journal Title
  
  Immunity
  
  Volume: 34 Pages: 149-162
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Local microbleeding facilitates IL-6-and IL-17-dependent arthritis in the absence of tissue antigen recognition by activated T cells2011
- Author(s)
  Murakami, M., Okuyama, Y., Ogura, H., Asano, S., Arima, Y., Tsuruoka, M., Harada, M., Kanamoto, M., Sawa, Y., Iwakura, Y., Takatsu, K., Kamimura, D., and Hirano, T.
- Journal Title
  
  J. Exp. Med.
  
  Volume: 208 Pages: 103-114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Functional specialization of interleukin-17 family members2011
- Author(s)
  Iwakura, Yoichiro
- Journal Title
  
  Immunity
  
  Volume: 34 Pages: 149-62
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21022016
[Journal Article] IL-1 receptor accessory protein-like 1 associated with mental retardation and autism mediates synapse formation by trans-synaptic interaction with protein tyrosine phosphatase2011
- Author(s)
  Yoshida, T., Yasumura, M., Uemura, T., Lee, S. J., Ra, M., Taguchi, R., Iwakura, Y., and Mishina, M.
- Journal Title
  
  J. Neurosci.
  
  Volume: 31 Pages: 13485-13499
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] The role of glucocorticoids in pregnancy, parturition, lactation, and nurturing in melanocortin receptor 2. deficient mice2011
- Author(s)
  Chida, D., Miyoshi, K., Sato, T., Yoda, T., Kikusui, T., and Iwakura, Y.
- Journal Title
  
  Endocrinology
  
  Volume: 152 Pages: 1652-1660
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Muramyldipeptide augments the actions of lipopolysacchairde in mice by stimulating macrophages to produe pro-IL-1B and by down-regulation of suppressor of cytokine signaling 1(SOCS1)2011
- Author(s)
  Shikama, Y., Kuroishi, T., Nagai, Y., Iwakura, Y., Shimauchi, H., Takada, H., Sugawara, S., and Endo, Y.
- Journal Title
  
  Innate Immun.
  
  Volume: 17 Pages: 54-59
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Functional specialization of interleukin-17 family members.2011
- Author(s)
  Iwakura, Y.
- Journal Title
  
  Immunity
  
  Volume: 34 Pages: 149-162
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] IL-1 signaling is dispensable for protective immunity in Leishmania-resistant mice2011
- Author(s)
  Kautz-Neu, K., Kostka, S. L., Dinges, S., Iwakura, Y., Udey, M. C., and Von Stebut, E.
- Journal Title
  
  Exp. Dermatol.
  
  Volume: 20 Pages: 76-78
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Memory/effector(CD45RBlo) CD4 T cells are controlled directly by IL-10 and cause IL-22-dependent intestinal pathology2011
- Author(s)
  Kamanaka, M., Huber, S., Zenewicz, L. A., Gagliani, N., Rathinam, C., O' Connor, W. Jr., Wan, Y. Y., Nakae, S., Iwakura, Y., Hao, L., and Flavell, R. A.
- Journal Title
  
  J. Exp. Med.
  
  Volume: 208 Pages: 1027-1040
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Interleukin 17 promotes angiotensin II-induced hypertension and vascular dysfunction.2010
- Author(s)
  Madhur, M.S., Lob, H.E., McCann, L.A., Iwakura, Y., Blinder, Y., Guzik, T.J., Harrison, D.G.
- Journal Title
  
  Hypertension 55
  
  Pages: 500-507
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Essential role of IL-17A in the formation of a mycobacterial infection-induced granuloma in the lung2010
- Author(s)
  Okamoto Yoshida, Y., Umemura, M., Yahagi, A., O' Brien, R. L., Ikuta, K., Kishihara, K., Hara, H., Nakae, S., Iwakura, Y., and Matsuzaki, G.
- Journal Title
  
  J. Immunol.
  
  Volume: 184 Pages: 4414-4422
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Activation of myeloid dendritic cells by deoxynucleic acids from Cordyceps sinensis via a Toll-like receptor 9-dependent pathway.2010
- Author(s)
  Xiao, G., Miyazato, A., Abe, Y., Zhang, T., Nakamura, K., Inden, K., Tanaka, M., Tanno, D., Miyasaka, T., Ishii, K., Takeda, K., Akira, S., Saijo, S., Iwakura, Y., Adachi, Y., Ohno, N., Yamamoto, N., Kunishima, H., Hirakata, Y., Kaku, M., Kawakami, K.
- Journal Title
  
  Cellular Immunol. 263
  
  Pages: 241-250
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Dectin-2 recognition of α-mannans and induction of Th17 differentiation is essential for host defense against Candida albicans.2010
- Author(s)
  Saijo, S., Ikeda, S., Yamabe, K., Kakuta, S., Ishigame, H., Akitsu, A., Fujikado, N., Kusaka, T., Kubo, S., Chung, S., Komatsu, R., Miura, N., Adachi, Y., Ohno, N., Shibuya, K., Yamamoto, N., Kawakami, K., Yamasaki, S., Saito, T., Akira, S., Iwakura, Y.
- Journal Title
  
  Immunity 32
  
  Pages: 1-11
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] IFN-regulates the requirement for IL-17 in proteoglycan-induced arthritis2010
- Author(s)
  Doodes, P. D., Cao, Y., Hamel, K. M., Wang, Y., Rodeghero, R. I., Mikecz, K., Glant T. T., Iwakura, Y., and Finnegan, A.
- Journal Title
  
  J. Immunol.
  
  Volume: 184 Pages: 1552-1559
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] IL-23 suppresses innate immune response independently of IL-17A during carcinogenesis and metastasis.2010
- Author(s)
  Teng, M.W.L., Andrews, D.M., McLaughlin, N., von Scheidt, B., Ngiow, S.F., Moller, A., Hill, G.R., Iwakura, Y., Oft, M., Smyth, M.J.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA 107
  
  Pages: 8328-33
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] IL-1 plays an important role in the bone metabolism under physiological conditions2010
- Author(s)
  Lee, Y.-M., Fujikado, N., Manaka, H., Yasuda, H., and Iwakura, Y.
- Journal Title
  
  Int. Immunol.
  
  Volume: 22 Pages: 805-816
- NAID
  10027907526
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Deficiency of interleukin-1 receptor antagonist induces aortic valve disease in BALB/c mice.2010
- Author(s)
  Isoda, K., Matsuki, T., Kondo, H., Iwakura, Y., Ohsuzu, F.
- Journal Title
  
  Arterioscler. Thromb. Vasc. Biol. 30
  
  Pages: 708-15
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Dectin-2 recognition ofα-mannans and induction of Th17 differentiation is essential for host defense against Candida albicans2010
- Author(s)
  Saijo, S., Ikeda, S., Yamabe, K., Kakuta, S., Ishigame, H., Akitsu, A., Fujikado, N., Kusaka, T., Kubo, S., Chung, S., Komatsu, R., Miura, N., Adachi, Y., Ohno, N., Shibuya, K., Yamamoto, N., Kawakami, K., Yamasaki, S., Saito, T., Akira, S., and Iwakura,
- Journal Title
  
  Immunity
  
  Volume: 32 Pages: 681-691
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Type I interferon signaling constrains IL-17A/F secretion by gd T cells during bacterial infection.2010
- Author(s)
  Henry, T., Kirimanjeswara, G.S., Ruby, T., Jones, J.W., Peng, K., Perret, M., Ho, L., Sauer, J. -D., Iwakura, Y., Metzger, D.W., Monack, D.M.
- Journal Title
  
  J. Immunol. 184
  
  Pages: 3755-67
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Nucleoprotein diet ameliorates arthritis symptoms in mice transgenic for human T-cell leukemia virus type I (HTLV-I).2010
- Author(s)
  Ohtaki, H., Yufu, S., Nakamachi, T., Satoh, K., Shimizu, A., Mori, H., Sato, A., Iwakura, Y., Matsunaga, M., Shioda, S.
- Journal Title
  
  J. Clin. Biochem. Nutr. 46
  
  Pages: 93-104
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] IL-17 contributes to the development of chronic rejection in a murine-heart transpant model.2010
- Author(s)
  Itoh, S., Nakae, S., Axtell, R.C., Velotta, J.B., Kimura, N., Kajiwara, N., Iwakura, Y., Saito, H., Adachi, H., Steinman, L., Robbins, R.C., Fishbein, M.P.
- Journal Title
  
  J. Clin. Immunol. 30
  
  Pages: 235-40
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Tumor-infiltrating IL-17-producing gammadelta T cells spport the progression of tumor via promoting angiogenesis.2010
- Author(s)
  Wakita, D., Sumida, K., Iwakura, Y., Nishikawa, H., Ohkuri, T., Chamoto, K., Kitamura, H., Nishimura, T.
- Journal Title
  
  Eur. J. Immunol. 15(Epub ahead of print)
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] A Th17-polarized cell population that has infiltrated the lung requires cells that convert to IFN-g production in order to induce airway hyperresponsiveness.2010
- Author(s)
  Ashino, S., Wakita, D., Shiohama, Y., Iwakura, Y., Chamoto, K., Ohkuri, T., Kitamura, H., Nishimura, T.
- Journal Title
  
  Int. Immunol. 22
  
  Pages: 503-513
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] TNF, but not IL-6 and IL-17, is crucial for the development of T cell-independent psoriasis-like dermatitis in Il1rn^<-/-> mice2010
- Author(s)
  Nakajima, A., Matsuki, T., Komine, M., Asahina, A., Horai, R., Nakae, S., Ishigame, H., Kakuta, S., Saijo, S., and Iwakura, Y.
- Journal Title
  
  J. Immunol.
  
  Volume: 185 Pages: 1887-1893
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Interleukin-17A upregulates receptor activator of NF-kappaB on osteoclast precursors.2010
- Author(s)
  Adamopoulos, I.E., Chao, C.C., Geissler, R., Laface, D., Blumenschein, W., Iwakura, Y., McClanahan, T., Bowman, E.P.
- Journal Title
  
  Arthritis Res. Ther. 12
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] L. Lung CD4-CD8-double-negative T cells are prominent producers of IL-17A and IFN-during primary respiratory murine infection with Francisella tularensis live vaccine strain2010
- Author(s)
  Cowley, S. C., Meierovics, A. I., Frelinger, J. A., Iwakura, Y., and Elkins, K.
- Journal Title
  
  J. Immunol.
  
  Volume: 184 Pages: 5791-5801
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] CXC chemokine receptor 4 expressed in T cells plays an important role in the development of collagen-induced arthritis2010
- Author(s)
  Chung, S. H., Seki, K., Choi, B. I., Kimura, K. B., Ito, A., Fujikado, N., Saijo, S., and Iwakura, Y.
- Journal Title
  
  Arthritis Res. Ther.
  
  Volume: 12 Pages: 188-188
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] IL-17 is necessary for host protection against acute-phase Trypanosoma cruzi infection2010
- Author(s)
  Miyazaki, Y., Hamano, S., Wang, S., Shimanoe, Y., Iwakura, Y., and Yoshida, H.
- Journal Title
  
  J. Immunol.
  
  Volume: 185 Pages: 1150-1157
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Lung CD4-CD8-double-negative T cells are prominent producers of IL-17A and IFN-gamma during primary respiratory murine infection with Francisella tularensis live vaccine strain.2010
- Author(s)
  Cowley, S.C., Meierovics, A.I., Frelinger, J.A., Iwakura, Y., Elkins, K.L.
- Journal Title
  
  J. Immunol. 184
  
  Pages: 5791-5801
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] M. Type I interferon signaling constrains IL-17A/F secretion byγδT cells during bacterial infection2010
- Author(s)
  Henry, T., Kirimanjeswara, G. S., Ruby, T., Jones, J. W., Peng, K., Perret, M., Ho, L., Sauer, J.-D., Iwakura, Y., Metzger, D. W., and Monack, D.
- Journal Title
  
  J. Immunol.
  
  Volume: 184 Pages: 3755-3767
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] D. Lipid-cytokine-chemokine cascade drives neutrophil recruitment in a murine model of inflammatory arthritis2010
- Author(s)
  Chou, R. C., Kim, N. D., Sadik, C. D., Seung, E., Lan, Y., Byrne, M. H., Haribabu, B., Iwakura, Y., and Luster, A.
- Journal Title
  
  Immunity
  
  Volume: 33 Pages: 266-278
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] IL-17A is dispensable for myocarditis but essential for the progression to dilated cardiomyopathy.2010
- Author(s)
  Baldeviano, G.C., Barin, J.G., Talor, M.V., Srinivasan, S., Bedja, D., Zheng, D., Gabrielson, K., Iwakura, Y., Rose, N.R., Cihakova, D.
- Journal Title
  
  Circulation Res. 106
  
  Pages: 1645-1655
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Stem cell mobilization with G-CSF induces Type-17 differentiation and promotes scleroderma.2010
- Author(s)
  Hill, G.R., Olver, S.D., Kuns, R.D., Varelias, A., Raffelt, N.C., Don, A.L.J., Markey, K.A., Wilson, Y.A., Smyth, M.J., Iwakura, Y., Tocker, J., Clouston, A., MacDonald, K.P.A.
- Journal Title
  
  Blood 30(Epub ahead of print)
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Th17 cells promote autoimmune anti-myeloperoxidase glomerulomephritits.2010
- Author(s)
  Gan, P.Y., Steinmetz, O.M., Tan, D.S., O'Sullivan, K.M., Ooi, J.D., Iwakura, Y., Kitching, A.R., Holdsworth, S.R.
- Journal Title
  
  J. Am. Soc. Nephrol. 21
  
  Pages: 925-931
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Identification of the cellular sensor that stimulates the inflammatory response to sterile cell death.2010
- Author(s)
  Kono, H., Karmarkar, D., Iwakura, Y., Rock, K.L.
- Journal Title
  
  J. Immunol. 184
  
  Pages: 4470-8
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] IFN-γregulates the requirement for IL-17 in proteoglycan-induced arthritis.2010
- Author(s)
  Doodes, P.D., Cao, Y., Hamel, K.M., Wang, Y., Rodeghero, R.I., Mikecz, K., Glant T.T., Iwakura, Y., Finnegan, A.
- Journal Title
  
  J. Immunol. 184
  
  Pages: 1552-1559
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Neural tube defects and impaired neural progenitor cell proliferation in G. 1-deficient mice2010
- Author(s)
  Okae, H., and Iwakura, Y.
- Journal Title
  
  Developmental Dynamics
  
  Volume: 239 Pages: 1089-1101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] IFN-γis a master regulator of endotoxin shock syndrome in mice primed with heat-killed Propionibacterium acnes.2010
- Author(s)
  Kawa, K., Tsutsui, H., Uchiyama, R., Kato, J., Matsui, K., Iwakura, Y., Matsumoto, T., Nakanishi, K.
- Journal Title
  
  Int. Immunol. 22
  
  Pages: 157-166
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] M. Virus binding to a plasma membrane receptor triggers interleukin-1α-mediated proinflammatory macrophage response in vivo2009
- Author(s)
  Di Paolo, N. C., Miao, E. A., Iwakura, Y., Kaja, M-K., Aderem, A., Flavell, R. A., Papayannopoulou, T., and Shayakhmetov, D.
- Journal Title
  
  Immunity
  
  Volume: 31 Pages: 110-121
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] MHC-matched corneal allograft rejection in an IFN-g/IL-17-independent manner in C57BL/6 mice.2009
- Author(s)
  Yamada, J., Hamuro, J., Fukushima, A., Ohteki, T., Terai, K., Iwakura, Y., Yagita, H., Kinoshita, S.
- Journal Title
  
  Invest. Ophthalmol. Vis. Sci. 50
  
  Pages: 2139-2146
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Pulmonary inflammation triggered by Ricin toxin requires macrophages and IL-1 signaling.2009
- Author(s)
  Lindauer, M.L., Wong, J., Iwakura, Y., Magun, B.E.
- Journal Title
  
  J. Immunol. 183
  
  Pages: 1419-1426
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Natural occurring IL-17 producing T cells regulagte the initial phase of neutrophil mediated airway responses.2009
- Author(s)
  Tanaka, S., Yoshimoto, T., Naka, T., Nakae, S., Iwakura, Y., Cua, D., Kubo, M.
- Journal Title
  
  J. Immunol. 183
  
  Pages: 7523-7530
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Role of T cell TGFβ signaling and IL-17 in allograft acceptance and fibrosis associated with chronic rejection2009
- Author(s)
  Faust, S.M., Lu, G., Marini, B.L., Zou, W., Gordon, D., Iwakura, Y., Laouar, Y., Bishop, D.K.
- Journal Title
  
  J.Immunol. 183
  
  Pages: 7297-7306
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21022016
[Journal Article] Interleukin (IL)-23 mediates Toxoplasma gondii-induced immunopathology in the gut via matrixmetalloproteinase-2 and IL-22 but independent of IL-17.2009
- Author(s)
  Munoz, M., Heimesaat, M. M., Danker, K., Struck, D., Lohmann, U., Plickert, R.,Bereswill, S., Fischer, A., Dunay, I. R., Wolk, K., Loddenkemper, C., Krell, H. -W., Libert, C., Lund, L. R., Frey, O., Holscher, C., Iwakura, Y., Ghilardi, N., Ouyang, W., Kamradt, T., Sabat, R., Liesenfeld, O. Interleukin
- Journal Title
  
  J. Exp. Med. 206
  
  Pages: 3047-3059
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Differential roles of IL-17A and IL-17F in host defense against mucoepithelial bacterial infection and allergic responses.2009
- Author(s)
  Ishigame, H., Kakuta, S., Nagai, T., Nambu, A., Komiyama, Y., Kadoki, M., Tanahashi, Y., Akitsu, A., Kotaki, H., Sudo, K., Nakae, S., Sasakawa, C., Iwakura, Y.
- Journal Title
  
  Immunity 30
  
  Pages: 108-119
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] A. A protective function for interleukin 17A in T cell-mediated intestinal inflammation2009
- Author(s)
  O' Connor, W. Jr., Kamanaka, M., Booth, C. J., Town, T., Nakae, S., Iwakura, Y., Kolls, J. K., and Flavell, R.
- Journal Title
  
  Nat. Immunol.
  
  Volume: 10 Pages: 603-609
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Dok-7 activates the muscle receptor kinase MuSK and shapes synapse formation2009
- Author(s)
  Inoue, A., Setoguchi, K., Matsubara, Y., Okada, K., Sato, N., Iwakura, Y., Higuchi, O., and Yamanashi, Y.
- Journal Title
  
  Science Signaling
  
  Volume: 2 Pages: 7-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Pivotal role of cerebral interleukin-17-producingγδT cells in the delayed phase of ischemic brain injury2009
- Author(s)
  Shichita, T., Sugiyama, Y., Ooboshi, H., Sugimori, H., Nakagawa, R., Takada, I., Iwaki, T., Okada, Y., Iida, M., Cua, D. J., Iwakura, Y., and Yoshimura, A.
- Journal Title
  
  Nat. Med.
  
  Volume: 15 Pages: 946-950
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] IL-17 promotes progression of cutaneous leishmaniasis in susceptible mice2009
- Author(s)
  Lopez Kostka, S., Dinges, S., Griewank, K., Iwakura, Y., Udey, M. C., and Von Stebut, E.
- Journal Title
  
  J. Immunol.
  
  Volume: 182 Pages: 3039-3046
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Tyrosine kinase 2 plays critical roles in the pathogenic CD4 T cell responses for the development of experimental autoimmune encephalomyelitis.2009
- Author(s)
  Oyamada, A., Ikebem H., Itsumi, M., Saiwai, H., Okada, S., Shimoda, K., Iwakura, Y., Nakayama, K.I., Iwamoto, Y., Yoshikai, Y., Yamada, H.
- Journal Title
  
  J. Immunol. 183
  
  Pages: 7539-7546
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Biotin status affects nickel allergy via regulation of IL-1b production in mice.2009
- Author(s)
  Kuroishi, T., Kinbara, M., Sato, N., Tanaka, Y., Nagai, Y., Iwakura, Y., Endo, Y., Sugawara, S.
- Journal Title
  
  J. Nutrition 139
  
  Pages: 1031-1036
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Characterization of mice deficient in Melanocortin 2 receptor on a B6/Balbc mix background2009
- Author(s)
  Chida, D., Sato, T., Sato, Y., Kubo, M., Yoda, T., Suzuki, H., and Iwakura, Y.
- Journal Title
  
  Mol. Cell. Endocrinol.
  
  Volume: 300 Pages: 32-36
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Hepatic platelet accumulation in Fas-mediated hepatitis in mice.2009
- Author(s)
  Ohtaki Y, Yamaguchi K, Yu Z, Kumamoto H, Shimauchi H, Iwakura Y, Sugawara S, Endo Y.
- Journal Title
  
  Int. Immunopharmacol. 9
  
  Pages: 1071-1078
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] T helper type 17 immune response plays an indispensable role for development of iodine-induced autoimmune thyroiditis in nonobese diabetic-H2h4 mice.2009
- Author(s)
  Horie, I., Abiru, N., Nagayama, Y., Kuriya, G., Saitoh, O., Ichikawa, T., Iwakura, Y., Eguchi, K.
- Journal Title
  
  Endocrinology 150
  
  Pages: 5135-5142
- NAID
  120002647079
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Role of T cell TGFβ signaling and IL-17 in allograft acceptance and fibrosis associated with chronic rejection2009
- Author(s)
  Faust, S.M., Lu, G., Marini, B.L., Zou, W., Gordon, D., Iwakura, Y., Laouar, Y., Bishop, D.K.
- Journal Title
  
  J.Immunol. 183
  
  Pages: 7297-7306
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Interleukin(IL)-23 mediates Toxoplasma gondii-induced immunopathology in the gut via matrixmetalloproteinase-2 and IL-22 but independent of IL-172009
- Author(s)
  Munoz, M., Heimesaat, M. M., Danker, K., Struck, D., Lohmann, U., Plickert, R., Bereswill, S., Fischer, A., Dunay, I. R., Wolk, K., Loddenkemper, C., Krell, H.-W., Libert, C., Lund, L. R., Frey, O., Holscher, C., Iwakura, Y., Ghilardi, N., Ouyang, W., Kamradt, T., Sabat, R., and Liesenfeld, O.
- Journal Title
  
  J. Exp. Med.
  
  Volume: 206 Pages: 3047-3059
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Toll-like receptor 9-dependent activation of myeloid dendritic cells by deoxynucleic acids from Candida albicans.2009
- Author(s)
  Miyazato A, Nakamura K, Yamamoto N, Mora-Montes HM, Tanaka M, Abe Y, Tanno D, Inden K, Gang X, Ishii K, Takeda K, Akira S, Saijo S, Iwakura Y, Adachi Y, Ohno N, Mitsutake K, Gow NA, Kaku M, Kawakami K.
- Journal Title
  
  Infect. Immun. 77
  
  Pages: 3056-3064
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Role of T cell TGFβsignaling and IL-17 in allograft acceptance and fibrosis associated with chronic rejection.2009
- Author(s)
  Faust, S.M., Lu, G., Marini, B.L., Zou, W., Gordon, D., Iwakura, Y., Laouar, Y., Bishop, D.K.
- Journal Title
  
  J. Immunol. 183
  
  Pages: 7297-7306
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] IL-17 promotes progression of cutaneous leishmaniasis in susceptible mice.2009
- Author(s)
  Lopez Kostka, S., Dinges, S., Griewank, K., Iwakura, Y., Udey, M.C., Von Stebut, E.
- Journal Title
  
  J. Immunol. 182
  
  Pages: 3039-3046
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Reciprocal differentiation and tissue-specific pathogenesis of Th1, Th2, and Th17 cells in graft versus host disease.2009
- Author(s)
  Yi, T., Chen, Y., Wang, L., Du, G., Huang, D., Zhao, D., Johnstone, H., Young, J., Todorov, I., Umetsu, D.T., Chen, L., Iwakura, Y., Kandeel, F., Forman, S., Zeng, D.
- Journal Title
  
  Blood 114
  
  Pages: 3101-3112
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] CXCL12 promotes CCR7-dependent naive T-cell trafficking to lymph nodes and Peyer's patches.2009
- Author(s)
  Bai, Z.B., Hayasaka, H., Kobayashi, M., Li, W., Guo, Z., Jang, M. -H., Kondo, A., Choi, B., Iwakura, Y., Miyasaka, M.
- Journal Title
  
  J. Immunol. 182
  
  Pages: 1287-1295
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Virus binding to a plasma membrane receptor triggers interleukin-1α-mediated proinflammatory macrophage response in vivo.2009
- Author(s)
  Di Paolo, N.C., Miao, E.A., Iwakura, Y., Kaja, M-K., Aderem, A., Flavell, R.A., Papayannopoulou, T., Shayakhmetov, D.M.
- Journal Title
  
  Immunity 31
  
  Pages: 110-121
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Interleukin-17 is required for T helper 1 cell immunity and host resistance to the intracellular pathogen Fracisella tularensis.2009
- Author(s)
  Lin, Y., Ritchea, S., Logar, A., Slight, S., Messmer, M., Rangel-Moreno, J., Guglani, L., Alcorn, J. F., Strawbridge, H., Park, S. M., Onishi, R., Nyugen, N., Walter, M. J., Pociask, D., Randall, T. D., Gaffen, S. L., Iwakura, Y., Kolls, J. K., Khader, S. A*.
- Journal Title
  
  Immunity 31
  
  Pages: 799-810
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Muramyldipeptide augments the actions of lipopolysacchairde in mice by stimulating macrophages to produe pro-IL-1b and by down-regulation of suppressor of cytokine signaling 1 (SOCS1).2009
- Author(s)
  Shikama, Y., Kuroishi, T., Nagai, Y., Iwakura, Y., Shimauchi, H., Takada, H., Sugawara, S., Endo, Y.
- Journal Title
  
  Innate Immun. (Epub ahead of print)
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] IL-17 is involved in bone resorption in mouse periapical lesions.2009
- Author(s)
  Oseko, F., Yamamoto, T., Akamatsu, Y., Kanamura, N., Iwakura, Y., Imanishi, J., Kita, M.
- Journal Title
  
  Microbiol. Immunol. 53
  
  Pages: 287-294
- NAID
  10027686578
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] E. Pulmonary inflammation triggered by Ricin toxin requires macrophages and IL-1 signaling2009
- Author(s)
  Lindauer, M. L., Wong, J., Iwakura, Y., and Magun, B.
- Journal Title
  
  J. Immunol.
  
  Volume: 183 Pages: 1419-1426
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Differential roles of IL-17A and IL-17F in host defense against mucoepithelial bacterial infection and allergic responses2009
- Author(s)
  Ishigame, H., Kakuta, S., Nagai, T., Nambu, A., Komiyama, Y., Kadoki, M., Tanahashi, Y., Akitsu, A., Kotaki, H., Sudo, K., Nakae, S., Sasakawa, C., and Iwakura, Y
- Journal Title
  
  Immunity
  
  Volume: 30 Pages: 108-119
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Interleukin-1 deficiency in combination with macrophage depletion increases susceptibility to Pseudomonas aeruginosa bacteremia.2009
- Author(s)
  Horino, T., Matsumoto, T., Ishikawa, H., Kimura, S., Uramatsu, M., Tanabe, M., Tateda, K., Miyazaki, S., Aramaki, Y., Iwakura, Y., Yoshida, M., Onodera, S., Yamaguchi, K.
- Journal Title
  
  Microbiol. Immunol. 53
  
  Pages: 502-511
- NAID
  10027687393
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Pivotal role of cerebral interleukin-17-producing gdT cells in the delayed phase of ischemic brain injury.2009
- Author(s)
  Shichita, T., Sugiyama, Y., Ooboshi, H., Sugimori, H., Nakagawa, R., Takada, I., Iwaki, T., Okada, Y., Iida, M., Cua, D.J., Iwakura, Y., Yoshimura, A.
- Journal Title
  
  Nat. Med. 15
  
  Pages: 946-950
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] A protective function for interleukin 17A in T cell-mediated intestinal inflammation.2009
- Author(s)
  O'Connor, W. Jr., Kamanaka, M., Booth, C.J., Town, T., Nakae, S., Iwakura, Y., Kolls, J.K., Flavell, R.A.
- Journal Title
  
  Nat. Immunol. 10
  
  Pages: 603-609
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Therapeutic effects of interleukin-6 blockade in a murine model of polymyositis that does not require interleukin-17A.2009
- Author(s)
  Okiyama, N., Sugihara, T., Iwakura, Y., Yokozeki, H., Miyasaka, N., Kohsaka, H.
- Journal Title
  
  Arth. Rheum. 60
  
  Pages: 2505-2512
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Host-derived Interleukin-1a is important in determining the immunogenicity of 3-Methylcholantrene-tumor cells.2009
- Author(s)
  Elkabets, M., Krelin, Y., Dotan, S., Cerwenka, A., Porgador, A., Lichtenstein, R.G., White, M.R., Zoller, M., Iwakura, Y., Dinarello, C.A., Voronov, E., Apte, R.N.
- Journal Title
  
  J. Immunol. 182
  
  Pages: 4874-4881
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Ozone exposure in a mouse model induces airway hyperreactivity that requires the presence of Natural Killer T cells and IL-172008
- Author(s)
  Pichavant, M., Goya, S., Meyer, E. H., Johnston, R. A., Kim, H. Y., Matangkasombut, P., Zhu, M., Iwakura, Y., Savage, P. B., DeKruyff, R. H., Shore, S. A., and Umetsu, D. T.
- Journal Title
  
  J. Exp. Med.
  
  Volume: 205 Pages: 385-393
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Either a Th17 or a Th1 effector response can drive autoimmunity: conditions of disease induction affect dominant effector category.2008
- Author(s)
  Luger, D., Silver, P.B., Tang, J., Cua, D., Chen, Z., Iwakura, Y., Bowman, E.P., Sgambellone, N.M., Chan, C. -C., Caspi, R.R.
- Journal Title
  
  J. Exp. Med. 205
  
  Pages: 799-810
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] IL-17 contributes to CD4-mediated graft-versus-host disease.2008
- Author(s)
  Kappel, L.W., Goldberg, G.L., King, C.G., Suh, D., Smith, O.M., Ligh, C., Holland, A., Grubin, J., Liu, C., Iwakura, Y., Mark, N., Heller, G., van den Brink, M.R.M.
- Journal Title
  
  Blood 113
  
  Pages: 628-636
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Deoxynucleic acids from Cryptococcus neoformans activate myeloid dendritic cells via a TLR9-dependent pathway.2008
- Author(s)
  Nakamura, K., Miyazato, A., Gang, X., Hatta, M., Inden, K., Aoyagi, T., Takeda, K., Akira, S., Saijo, S., Iwakura, Y., Adachi, Y., Ohno, N., Suzuki, K., Fujita, J., Kaku, M., Kawakami, K.
- Journal Title
  
  J. Immunol. 180
  
  Pages: 4067-4074
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Critical role for mesothelial cells in necrosis-induced inflammation through the recognition of IL-1a released from dying cells.2008
- Author(s)
  Eigenbrod, T., Park, J-H., Harder, J., Iwakura, Y., Nunez, G.
- Journal Title
  
  J. Immunol. 181
  
  Pages: 8194-8198
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Interleukin-1b and macrophage migration inhibitory factor (MIF) in dermal fibroblasts mediate UVA induced matrix metalloproteinase-1 expression.2008
- Author(s)
  Honda, A., Abe, R., Makino, T., Norisugi, O., Fujita, Y., Watanabe, H., Nishihira, J., Yamagishi, S., Iwakura, Y., Shimizu, H., Shimizu, T.
- Journal Title
  
  J. Dermatol. Sci. 49
  
  Pages: 63-72
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] L-17A produced by gammadelta T cells plays a critical role in innate immunity against Listeria monocytogenes infection in the liver.2008
- Author(s)
  Hamada, S., Umemura, M., Shiono, T., Tanaka, K., Yahagi, A., Begum, M.D., Oshiro, K., Okamoto, Y., Watanabe, H., Kawakami, K., Roark, C., Born, W.K., O'Brien, R., Ikuta, K., Ishikawa, H., Nakae, S., Iwakura, Y., Ohta, T., Matsuzaki, G.
- Journal Title
  
  J. Immunol. 181
  
  Pages: 3456-3463
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Either a Th17 or a Th1 effector response can drive autoimmunity : conditions of disease induction affect dominant effector category2008
- Author(s)
  Luger, D., Silver, P. B., Tang, J., Cua, D., Chen, Z., Iwakura, Y., Bowman, E. P., Sgambellone, N. M., Chan, C.-C. and Caspi, R.
- Journal Title
  
  J. Exp. Med.
  
  Volume: 205 Pages: 799-810
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Contribution of IL-1 to resistance to Streptococcus pneumoniae infection2008
- Author(s)
  Kafka, D., Ling, E., Feldman, G., Benharroch, D., Voronov, E., Givon-Laci, N., Iwakura, Y., Dagan, R., Apte, R. N., and Mizrachi-Nebenzahi, Y.
- Journal Title
  
  Int. Immunol.
  
  Volume: 9 Pages: 1139-1146
- NAID
  10022599302
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] IL-23 and Th17 cells enhance Th2 cell-mediated eosinophilic airway inflammation in mice.2008
- Author(s)
  Wakashin, H., Hirose, K., Maezawa, Y., Kagami, S., Suto, A., Watanabe, N., Saito, Y., Hatano, M., Tokuhisa, T., Iwakura, Y., Puccetti, P., Iwamoto, I., Nakajima, H.
- Journal Title
  
  Am. J. Respir. Crit. Care Med. 178
  
  Pages: 1023-1032
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Differential roles for IFN-g and IL-17 in experimental autoimmune uveoretinitis.2008
- Author(s)
  Yoshimura, T., Sonoda, K., Miyazaki, Y., Iwakura, Y., Ishibashi, T., Yoshimura, A., Yoshida, H.
- Journal Title
  
  Int. Immunol. 20
  
  Pages: 209-214
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Interleukin-17 promotes autoimmunity by triggering a positive-feedback loop via interleukin-6 induction.2008
- Author(s)
  Ogura H., Murakami, M., Okyuyama, Y., Tsuruoka, M., Kitabayashi, C., Kanamoto, M., Nishihara, M., Iwakura, Y., Hirano, T*.
- Journal Title
  
  Immunity 29
  
  Pages: 628-636
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] IL-1 regulates the Cyp7a1 gene and serum total cholesterol level at steady state in mice.2008
- Author(s)
  Kojima, M., Ashino, T., Yoshida, T., Iwakura, Y., Sekimoto, M., Degawa, M.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 379
  
  Pages: 239-242
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Endogenous IL-17 does not play a significant role in the development of experimental murine allergic conjunctivitis.2008
- Author(s)
  Fukushima, A., Sumi, T., Ishida, W., Yamada, J., Iwakura, Y., Ueno, H.
- Journal Title
  
  Int. Arch. Allergy Imm. 147
  
  Pages: 206-212
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Contribution of IL-1 to resistance to Streptococcus pneumoniae infection.2008
- Author(s)
  Kafka, D., Ling, E., Feldman, G., Benharroch, D., Voronov, E., Givon-Laci, N., Iwakura, Y., Dagan, R., Apte, R.N., Mizrachi-Nebenzahi, Y.
- Journal Title
  
  Int. Immunol. 9
  
  Pages: 1139-1146
- NAID
  10022599302
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] K. IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia2008
- Author(s)
  Aujla, S. J., Fei, M., Pociask, D. A., Reinhart, T. A., Edeal, J., Gaus, K., Kreindler, J. L., Dubin, P. J., Zheng, M., Pilewski, J. M., Myerburg, M. M., Mason, C. A., Iwakura, Y., and Kolls, J.
- Journal Title
  
  Nature Med.
  
  Volume: 14 Pages: 275-281
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] The roles of IL-17A in inflammatory immune responses and host defense against pathogens2008
- Author(s)
  Iwakura, Y.
- Journal Title
  
  Immanol. Rev. 226
  
  Pages: 57-79
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Increased fat-to-carbohydrate oxidation ratio in Il1ra^<-/-> mice on a high fat diet is associated with increased sympathetic tone2008
- Author(s)
  Chida, D., Hashimoto, O., Kuwahara, M., Sagara, H., Osaka, T., Tsubone, H., and Iwakura, Y.
- Journal Title
  
  Diabetologia
  
  Volume: 51 Pages: 1698-1706
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Ozone exposure in a mouse model induces airway hyperreactivity that requires the presence of Natural Killer T cells and IL-17.2008
- Author(s)
  Pichavant, M., Goya, S., Meyer, E.H., Johnston, R.A., Kim, H.Y., Matangkasombut, P., Zhu, M., Iwakura, Y., Savage, P.B., DeKruyff, R.H., Shore, S.A., Umetsu, D.T.
- Journal Title
  
  J. Exp. Med. 205
  
  Pages: 385-393
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] CCL2 recruitment of IL-6 producing CD11b+ monocytes to the draining lymph nodes during the initiation of TH17-dependent B cellmediated autoimmunity.2008
- Author(s)
  Bai, Y, Liu, R., Huang, D., La Cava, A., Tang, Y., Iwakura, Y., Campagnolo, D.I., Vollmer, T.L., Ransohoff, R.M., Shi, F.
- Journal Title
  
  Eur. J. Immunol. 38
  
  Pages: 1877-1888
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] CD44 and Bak expression in IL-6 or TNF-a gene knockout mice after whole lung irradiation.2008
- Author(s)
  Sakai, M., Iwakawa, M., Iwakura, Y., Ohta, T., Tsujii, H., Imai, T.
- Journal Title
  
  J. Radiat. Res. 49
  
  Pages: 409-416
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] The roles of IL-17A in inflammatory immune responses and host defense against pathogens.2008
- Author(s)
  Iwakura, Y., Nakae, S., Saijo, S., Ishigame, H.
- Journal Title
  
  Immunological Rev. 226
  
  Pages: 57-79
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] The roles of IL-17A in inflammatory immune responses and host defense against pathogens.2008
- Author(s)
  iwakura, Y.
- Journal Title
  
  Immunol. Rev., 226
  
  Pages: 57-79
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Negative feedback regulation of lipopolysaccharide-induced inducible nitric oxide synthase gene expression by heme oxygenase-1 induction in macrophages.2008
- Author(s)
  Ashino, T., Yamanaka, R., Yamamoto, M., Shimokawa, H., Sekikawa, K., Iwakura, Y., Shioda, S., Numazawa, S., Yoshida, T.
- Journal Title
  
  Mol. Immunol. 45
  
  Pages: 2106-2115
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Development of proteogylcan-induced arthritis is independent of IL-17.2008
- Author(s)
  Doodes, P.D., Cao, Y., Hamel, K., Wang, Y., Hutas, G., Iwakura, Y., Finnegan, A.
- Journal Title
  
  J. Immunol. 181
  
  Pages: 329-337
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Deficiency of tumor necrosis factor-a and interferon-g in bone marrow cells synergistically inhibits neointimal formation following vascular injury.2008
- Author(s)
  Murayama, H., Takahashi, M., Takamoto, M., Shiba, Y., Ise, H., Koyama, J., Tagawa, Y., Iwakura, Y., Ikeda, U.
- Journal Title
  
  Cardiovascular Res. 80
  
  Pages: 175-180
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Interleukin-23 restrains regulatory T cell activity to drive T cell-dependent colitis.2008
- Author(s)
  Izcue, A., Hue, S., Buonocore, S., Arancibia-Carcamo, C.V., Ahern, P.P., Iwakura, Y., Maloy, K.J., Powrie, F
- Journal Title
  
  Immunity 28
  
  Pages: 559-570
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Protective immunity to systemic infection with Salmonella enterica serovar Enteritidis in the absence of IL-12 is associated with IL-23-dependent IL-22 but not IL-17.2008
- Author(s)
  Schulz, S.M., Kohler, G., Schutze, N., Knauer, J., Straubinger, R.K., Chackerian, A.A., Witte, E., Wolk, K., Sabat, R., Iwakura, Y., Holscher, C., Muller, U., Kastelein, R.A., Alber, G.
- Journal Title
  
  J. Immunol. 181
  
  Pages: 7891-7901
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Interleukin-23 restrains regulatory T cell activity to drive T cell-dependent colitis2008
- Author(s)
  Izcue, A., Hue, S., Buonocore, S., Arancibia-Carcamo, C. V., Ahern, P. P., Iwakura, Y., Maloy, K. J., and Powrie, F
- Journal Title
  
  Immunity
  
  Volume: 28 Pages: 559-570
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Human T-cell leukemia virus type I infects human lung epithelial cells and induces gene expression of cytokines, chemokines and cell adhesion molecules.2008
- Author(s)
  Teruya, H., Tomita, M., Senba, M., Ishikawa, C., Tamayose, M., Miyazato, A., Yara, S., Tanaka, Y., Iwakura, Y., Fujita, J., Mori, N.
- Journal Title
  
  Retrovirology 5
  
  Pages: 86-86
- NAID
  120001374675
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Dcir deficiency causes development of autoimmune diseases in mice due to excess expansion of dendritic cells.2008
- Author(s)
  Fujikado, N., Saijo, S., Yonezawa, T., Shimamori, K., Ishii, A., Sugai, S., Kotaki, H., Sudo, K., Nose, M., Iwakura, Y.
- Journal Title
  
  Nat. Med. 14
  
  Pages: 176-180
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] The roles of IL-17A in inflammatory immune responses and host defense against pathogens2008
- Author(s)
  Iwakura, Y.
- Journal Title
  
  Immunol. Rev. 226
  
  Pages: 57-79
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19041025
[Journal Article] The roles of IL-17A in inflammatory immune responses and host defense against pathogens2008
- Author(s)
  Iwakura, Y.
- Journal Title
  
  Immunol. Rev 226
  
  Pages: 57-79
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015015
[Journal Article] The roles of IL-17A in inflammatory immune responses and host defence against pathogens2008
- Author(s)
  Iwakura Y
- Journal Title
  
  Immunol Rev. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240041
[Journal Article] The roles of IL-17A in inflammatory immune responses and host defense against pathogens2008
- Author(s)
  Iwakura, Y., Nakae, S., Saijo, S., and Ishigame, H.
- Journal Title
  
  Immunological Rev.
  
  Volume: 226 Pages: 57-79
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] The role of DCIR in the development of autoimmune diseases2008
- Author(s)
  Fujikado, N., Saijo, S., Yonezawa, T., Shimamori, K., Ishii, A., Sugai, S., Kotaki, H., Sudo, K., Nose, M., and Iwakura, Y.
- Journal Title
  
  Cytokine
  
  Volume: 43 Pages: 244-244
- NAID
  40017145116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] L-6-dependent spontaneous proliferation is required for the induction of colitogenic IL-17-producing CD8+ T cells2008
- Author(s)
  Tajima, M., Wakita, D., Noguchi, D., Chamoto, K., Yue, Z, Fugo, K., Ishigame, H., Iwakura, Y., Kitamura, H., Nishimura, T.
- Journal Title
  
  J. Exp. Med. 205
  
  Pages: 1019-1027
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Suppressive role of leukocyte cell-derived chemotaxin 2 in mouse anti-type II collagen antibody-induced arthritis.2008
- Author(s)
  Okumura, A., Saito, T., Otani, I., Kojima, K., Yamada, Y., Ishida-Okawara, A., Nakazato, K., Asano, M., Kanayama, K., Iwakura, Y., Suzuki, K., Yamagoe, S.
- Journal Title
  
  Arthritis Rheum. 58
  
  Pages: 413-421
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] IFN-γexpression in CD8+ T cells regulated by IL-6 signal is involved in superantigen-mediated CD4+ T cell death.2008
- Author(s)
  Atsumi, T., Sato, M., Kamimura, D., Moroi, A., Iwakura, Y., Betz, U.A., Yoshimura, A., Nishihara, M., Hirano, T., Murakami, M.
- Journal Title
  
  Int. Immunol. 21
  
  Pages: 73-80
- NAID
  10025383990
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Involvement of IL-17A in the pathogenesis of DSS-induced colitis in mice.2008
- Author(s)
  Ito, R., Kita, M., Shin-Ya, M., Kishida, T., Urano, A., Takada, R., Sakagami, J., Imanishi, J., Iwakura, Y., Okanoue, T., Yoshikawa, T., Kataoka, K., Mazda, O.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 377
  
  Pages: 12-16
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Toll-like receptor 2 (TLR2) and dectin-1 contribute to the production of IL-12p40 by bone marrow-derived dendritic cells infected with Penicillium marneffei.2008
- Author(s)
  Nakamura, K., Miyazato, A., Koguchi, Y., Adachi, Y., Ohno, N., Saijo, S., Iwakura, Y., Takeda, K., Akira, S., Fujita, J., Ishii, K., Kaku, M., Kawakami, K.
- Journal Title
  
  Microbes Infect. 10
  
  Pages: 1223-1227
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] IL-17A is produced by Th17 cells, γδ T cells and other CD4- lymphocytes during infection with Salmonella enterica serovar Enteritidis and has a mild effect in bacterial clearance.2008
- Author(s)
  Schulz, S.M., Kohler, G., Holscher, C., Iwakura, Y., Alber, G*.
- Journal Title
  
  Int. Immunol. 9
  
  Pages: 1129-1138
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] The mechanisms of the stress-induced behavioral abnormality in the IL-1 receptor antagonist(IL-1Ra) KO mice2008
- Author(s)
  Wakabayashi, C., and Iwakura, Y.
- Journal Title
  
  Neuroscience Res.
  
  Volume: 61 Pages: 63-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Interleukin-17 promotes autoimmunity by triggering a positive-feedback loop via interleukin-6 induction2008
- Author(s)
  Ogura, H., Murakami, M., Okyuyama, Y., Tsuruoka, M., Kitabayashi, C., Kanamoto, M., Nishihara, M., Iwakura, Y., and Hirano, T.
- Journal Title
  
  Immunity
  
  Volume: 29 Pages: 628-636
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia.2008
- Author(s)
  Aujla, S.J., Fei, M., Pociask, D.A., Reinhart, T.A., Edeal, J., Gaus, K., Kreindler, J.L., Dubin, P.J., Zheng, M., Pilewski, J.M., Myerburg, M.M., Mason, C.A., Iwakura, Y., Kolls, J.K.
- Journal Title
  
  Nature Med. 14
  
  Pages: 275-281
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] L-6-dependent spontaneous proliferation is required for the induction of colitogenic IL-17-producing CD8^+T cells2008
- Author(s)
  Tajima, M., Wakita, D., Noguchi, D., Chamoto, K., Yue, Z, Fugo, K., Ishigame, H., Iwakura, Y., Kitamura, H., and Nishimura, T
- Journal Title
  
  J. Exp. Med.
  
  Volume: 205 Pages: 1019-1027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Host T cells are the main producers of IL-17 within the central nervous system during initiation of experimental autoimmune encephalomyelitis induced by adoptive transfer of Th1 cell lines.2008
- Author(s)
  Lees, J.R., Iwakura, Y., Russell, J.H.
- Journal Title
  
  J. Immunol. 180
  
  Pages: 8066-8072
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] IL-17と新規I1-17産生ヘルパーT細胞サブセット2007
- Author(s)
  岩倉洋一郎
- Journal Title
  
  感染・炎症・免疫 (印刷中)
- Data Source
  KAKENHI-PROJECT-17390140
[Journal Article] Alteration of behavioural phenotype in mice by targeted disruption of the progranulin gene.2007
- Author(s)
  Kayasuga, Y., Chiba, S., Suzuki, M., Kikusui, T., Matsuwaki, T., Yamanouchi, K., Kotaki, H., Horai, R., Iwakura, Y., Nishihara, M.
- Journal Title
  
  Behav. Brain Res. 185
  
  Pages: 110-118
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Differential role and tissue specificity of interleukin-1alpha gene expression in atherogenesis and lipid metabolism.2007
- Author(s)
  Kamari, Y., Werman-Venkert, R., Shaish, A., Werman, A., Harari, A., Gonen, A., Voronov, E., Grosskopf, I., Sharabi, Y., Grossman, E., Iwakura, Y., Dinarello, C.A., Apte, R.N., Harats, D.
- Journal Title
  
  Atherosclerosis 195
  
  Pages: 31-38
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Melanocortin receptor 2 is required for adrenal gland development, steroidogenesis and neonatal gluconeogenesis.2007
- Author(s)
  Chida, D., Nakagawa, S., Nagai, S., Sagara, H., Katsumata, H., Imaki, T., Suzuki, H., Mitani, F., Ogishima, T., Shimizu, C., Kotaki, H., Kakuta, S., Sudo, K., Koike, T., Kubo, M., Iwakura, Y.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA 104
  
  Pages: 18205-18210
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Anti-type II collagen antibody accelerates arthritis via CXCR2-expressing cells in IL-1 receptor antagonist-deficient mice.2007
- Author(s)
  Kagari, T., Tanaka, D., Doi, H., Iwakura, Y., Shimozato, T.
- Journal Title
  
  Eur. J. Immunol. 37
  
  Pages: 2753-2763
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] IL-17と新規I1-17産生ヘルパーT細胞サブセット2007
- Author(s)
  岩倉洋一郎
- Journal Title
  
  感染・炎症・免疫 (印刷中)
- Data Source
  KAKENHI-PROJECT-17047011
[Journal Article] Inflammasome-mediated production of IL-1b is required for neutrophil recruitment against Staphylococcus aureus in vivo.2007
- Author(s)
  Miller, L.S., Pietras, E.M., Uricchio, L.H., Hirano, K., Rao, S., Lin, H., O'Connell, R.M., Iwakura, Y., Cheung, A.L., Cheng, G., Modlin, R.L.
- Journal Title
  
  J. Immunol. 179
  
  Pages: 6933-6942
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] IL-17と新規Il-17産生ヘルパーT細胞サブセット2007
- Author(s)
  岩倉洋一郎
- Journal Title
  
  感染・炎症・免疫 (印刷中)
- Data Source
  KAKENHI-PROJECT-18060010
[Journal Article] Blocking of IL-6 signaling pathway prevents CD4+ T cell-mediated colitis in a Th17-independent manner.2007
- Author(s)
  Noguchi, D., Wakita, D., Tajima, M., Ashino, S., Iwakura, Y., Zhang, Y., Chamoto, K., Kitamura, H., Nishimura, T.
- Journal Title
  
  Int. Immunol. 19
  
  Pages: 1431-1440
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Knockout mice lacking cPGES/p23, a constitutively expressed PGE(2) synthetic enzyme, are peri-natally lethal.2007
- Author(s)
  Nakatani, Y., Hokonohara, Y., Kakuta, S., Sudo, K., Iwakura, Y., Kudo, I.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 362
  
  Pages: 387-92
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Involvement of protein-tyrosine phosphatase PTPMEG in motor learning and cerebellar long-term depression.2007
- Author(s)
  Kina, S., Tezuka, T., Kusakawa, S., Kishimoto, Y., Kakizawa, S., Hashimoto, K., Ohsugi, M., Kiyama, Y., Horai, R., Sudo, K., Kakuta, S., Iwakura, Y., Iino, M., Kano, M., Manabe, T., Yamamoto, T.
- Journal Title
  
  Eur. J. Neurosci. 26
  
  Pages: 2269-2278
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] The role of TNF a and IL-17 in the development of excess IL-1 signaling-induced inflammatory diseases in IL-1 receptor antagonist-deficient mice.2006
- Author(s)
  Ishigame, H., Nakajima, A., Saijo, S., Komiyama, Y., Nambu, A., Matsuki, T., Nakae, S., Horai, R., Kakuta, S., Iwakura, Y.
- Journal Title
  
  Ernst Schering Res Found Workshop.: 56
  
  Pages: 129-153
- Data Source
  KAKENHI-PROJECT-17500284
[Journal Article] The IL-23/IL-17 axis in inflammation2006
- Author(s)
  Iwakura Y.
- Journal Title
  
  J Clin Invest 116
  
  Pages: 1218-1222
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390140
[Journal Article] CD28-dependent differentiation into the effector/memory phenotype is essential for induction of arthritis in interleukin-1 receptor antagonist-deficient mice2006
- Author(s)
  Kotani, M., Hirata, K., Ogawa, S., Habiro K., Ishida, Y., Tanuma, S., Horai R., Iwakura, Y., Kishimoto, H., Abe R
- Journal Title
  
  Arthritis Rheum. 53
  
  Pages: 473-481
- Data Source
  KAKENHI-PROJECT-17047011
[Journal Article] The IL-23/IL-17 axis in inflammation.2006
- Author(s)
  Iwakura Y.
- Journal Title
  
  J. Clin Invest 116
  
  Pages: 1218-1222
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390140
[Journal Article] The IL-23/IL-17 axis in inflammation.2006
- Author(s)
  Iwakura, Y.
- Journal Title
  
  J. Clin. Invest. 116(5)
  
  Pages: 1218-22
- Data Source
  KAKENHI-PROJECT-17390140
[Journal Article] Combined IL-6 and IL-1 deficiency causes obesity in young mice.2006
- Author(s)
  Chida, D., Osaka, T., Hashimoto, O., Iwakura, Y.
- Journal Title
  
  Diabetes 55
  
  Pages: 971-977
- Data Source
  KAKENHI-PROJECT-16046207
[Journal Article] The role of TNF a and IL-17 in the development of excess IL-1 signaling-induced inflammatory diseases in IL-1 receptor antagonist-deficient mice.2006
- Author(s)
  Ishigame, H., Nakajima, A., Saijo S., Komiyama, Y., Nambu, A., Matsuki, T., Nakae, S., Horai, R., Kakuta, S., Iwakura, Y
- Journal Title
  
  Ernst Schering Res Found Workshop. 56
  
  Pages: 129-153
- Data Source
  KAKENHI-PROJECT-17047011
[Journal Article] The IL-23/IL-17 axis in inflammation.2006
- Author(s)
  Iwakura, Y.
- Journal Title
  
  J. Clin. Invest. 116(5)
  
  Pages: 1218-1222
- Data Source
  KAKENHI-PROJECT-18060010
[Journal Article] CD28-dependent differentiation into the effector/memory phenotype is essential for induction of arthritis in interleukin-1 receptor antagonist-deficient mice2006
- Author(s)
  Kotani, M., Hirata, K., Ogawa, S., Habiro, K.Ishida, Y., Tanuma, S., Horai R., Iwakura, Y., Kishimoto, H., Abe, R
- Journal Title
  
  Arthritis Rheum. 53
  
  Pages: 473-481
- Data Source
  KAKENHI-PROJECT-17390140
[Journal Article] Abnormal T cell activation caused by the imbalance of the IL-1/IL-1R antagonist system is responsible for the development of experimental autoimmune encephalomyelitis.2006
- Author(s)
  Matsuki I., Nakae, S., Sudo, K., Horai, R., Iwakura, Y.
- Journal Title
  
  Int.Immunol., 18
  
  Pages: 399-340
- NAID
  10020621858
- Data Source
  KAKENHI-PROJECT-17390140
[Journal Article] The role of TNF a and IL-17 in the development of excess IL-1 signaling-induced inflammatory diseases in IL-1 receptor antagonist-deficient mice.2006
- Author(s)
  Ishigame, H., Nakajima, A., Saijo S., Komiyama, Y., Nambu, A., Matsuki, T., Nakae, S., Horai, R., Kakuta, S., Iwakura.Y
- Journal Title
  
  Ernst Schering Res Found Workshop. 56
  
  Pages: 129-153
- Data Source
  KAKENHI-PROJECT-17390140
[Journal Article] The IL-23/IL-17 axis in inflammation.2006
- Author(s)
  Iwakura, Y.
- Journal Title
  
  J. Clin. Invest. 116(5)
  
  Pages: 1218-1222
- Data Source
  KAKENHI-PROJECT-17047011
[Journal Article] Abnormal T cell activation caused by the imbalance of the IL-1/IL-1R antagonist system is responsible for the development of experimental autoimmune encephalomyelitis.2006
- Author(s)
  Matsuki, T., Nakae S., Sudo, K., Horai, R., Iwakura, Y.
- Journal Title
  
  Int.Immunol., 18
  
  Pages: 399-340
- NAID
  10020621858
- Data Source
  KAKENHI-PROJECT-17047011
[Journal Article] Involvement of corticotropin-releasing hormone-and interleukin-6-dependent proopiomelanocortin induction in the anterior Pituitary during hypothalamic-pituitary-adrenal axis activation by IL-1α.2005
- Author(s)
  Chida, D., Imaki, T., Suda, T., Iwakura Y
- Journal Title
  
  Endocrinology,: 146
  
  Pages: 5496-5502
- Data Source
  KAKENHI-PROJECT-17047011
[Journal Article] Arthritis in mice that are deficient in interleukin-1 receptor antagonist is dependent on genetic background.2005
- Author(s)
  Zho, F., He, X., Iwakura, Y., Horai, R., Stuart JM
- Journal Title
  
  Arthritis Rheum. 52
  
  Pages: 3731-3738
- Data Source
  KAKENHI-PROJECT-17390140
[Journal Article] Involvement of corticotropin-releasing hormone-and interleukin-6-dependent proopiomelanocortin induction in the anterior pituitary during hypothalamic-pituitary-adrenal axis activation by IL-1α.2005
- Author(s)
  Chida, D., Imaki I., Suda, I., Iwakura, Y
- Journal Title
  
  Endocrinology,: 146
  
  Pages: 5496-5502
- Data Source
  KAKENHI-PROJECT-17390140
[Journal Article] Involvement of CRH-and IL-6-dependent proopiomelanocortin induction in the anterior pituitary during hypothalamic-pituitary-adrenal axis activation by IL-Ia.2005
- Author(s)
  Chida, D., Imaki, T., Suda, T., Iwakura, Y.
- Journal Title
  
  Endocrinology 146
  
  Pages: 5496-5502
- Data Source
  KAKENHI-PROJECT-16046207
[Journal Article] Involvement of tumor necrosis factor-alpha in the development of T cell-dependent aortitis in interleukin-1 receptor antagonist-deficient mice.2005
- Author(s)
  Matsuki, T., Isoda, K., Horai, R., Nakajima A., Aizawa Y., Suzuki, K., Ohsuzu, F., Iwakura, Y.
- Journal Title
  
  Circulation 30
  
  Pages: 1323-1331
- Data Source
  KAKENHI-PROJECT-17047011
[Journal Article] Arthritis In mice that are deficient in interlelukin-1 receptor antagonist is dependent on genetic background.2005
- Author(s)
  Zho, F., He, X., Iwakura, Y., Horai, R., Stuart, JM
- Journal Title
  
  Arthritis Rheum. 52
  
  Pages: 3731-3738
- Data Source
  KAKENHI-PROJECT-17047011
[Journal Article] Involvement of tumor necrosis factor-alpha in the development of T cell-dependent aortitis in interleukin-1 receptor antagonist-deficient mice.2005
- Author(s)
  Matsuki, I., Isoda, K., Horai, R., Nakajima, A., Aizawa Y., Suzuki, K., Ohsuzu, F., Iwakura, Y.
- Journal Title
  
  Circulation 30
  
  Pages: 1323-1331
- Data Source
  KAKENHI-PROJECT-17390140
[Journal Article] Deficiency of interleukin-1 receptor antagonist deteriorates fatty-liver and cholesterol metabolism in hypercholesterolemic mice.2005
- Author(s)
  Isoda K, Sawada S, Ayaori M, Matsuki T, Horai R, Kagata Y, Miyazaki K, Kusuhara M, Okazaki M, Matsubara O, Iwakura Y, Ohsuzu F.
- Journal Title
  
  J Biol Chem. 280・8
  
  Pages: 7002-7009
- Data Source
  KAKENHI-PROJECT-16046207
[Journal Article] Distinct contribution of IL-6, TNF-α, IL-1, and IL-10 to T cell-mediated spontaneous autoimmune arthritis in mice.2004
- Author(s)
  Hata, H., Sakaguchi, N., Iwakura, Y., Sakaguchi, S et al.
- Journal Title
  
  J.Clin.Invest 114
  
  Pages: 582-588
- Data Source
  KAKENHI-PROJECT-16043216
[Journal Article] Induction of IgG2a class switching in B cells by IL-272004
- Author(s)
  Yoshimoto, T., Iwakura, Y., Mizuguchi, J et al.
- Journal Title
  
  J.Immunol 173
  
  Pages: 2479-2485
- Data Source
  KAKENHI-PROJECT-16012209
[Journal Article] Distinct contribution of IL-6, TNF-α, IL-1, and IL-10 to T cell-mediated spontaneous autoimmune arthritis in mice.2004
- Author(s)
  Hata, H., Sakaguchi, N., Iwakura, Y., Sakaguchi, S et al.
- Journal Title
  
  J.Clin.Invest 114
  
  Pages: 582-588
- Data Source
  KAKENHI-PROJECT-16012209
[Journal Article] IL-6, but not IL-1, induction in the brain downstream of Cox-2 is essential for the induction of febrile response against peripheral IL-1α.2004
- Author(s)
  Kagiwada, K., Chida, D., Iwakura, Y
- Journal Title
  
  Endocrinology 145
  
  Pages: 5044-5048
- Data Source
  KAKENHI-PROJECT-16012209
[Journal Article] Evaluation of the effect of sulfamethoxazole on Toxoplasma gondii loads and stage conversion in IFN-g knockout mice using QC-PCR2004
- Author(s)
  Usama S.Belal, Norose K, Aosai F, Mun H-S, Azza K.Ahmed, Chen M, Rabie M.Mohamed, Piao L-X, Iwakura Y, Yano A
- Journal Title
  
  Microbiol.Immunol. 48(3)
  
  Pages: 185-193
- Data Source
  KAKENHI-PROJECT-15390135
[Journal Article] The point mutation of tyrosine 759 of the IL-6 family cytokine receptor gp130 synergizes with HTLV-1 pX in promoting rheumatoid arthritis-like arthritis2004
- Author(s)
  Ishihara, K., Sawa, S.Iwakura, Y., Hirano, T et al.
- Journal Title
  
  Int Immunol 16
  
  Pages: 455-465
- NAID
  10013084315
- Data Source
  KAKENHI-PROJECT-16012209
[Journal Article] IL-6 regulates in vivo dendritic cell differentiation through STAT3 activation2004
- Author(s)
  Park, S.J., Iwakura, Y., Ishihara.K, M., Hirano, T.et al.
- Journal Title
  
  J.Immunol 173
  
  Pages: 3844-3854
- Data Source
  KAKENHI-PROJECT-16043216
[Journal Article] The role of IFN-γ and toll-like receptors in nephropathy induced by Toxoplasma gondii infection.2004
- Author(s)
  Kudo M., Aosai F., Mun H-S., Norose K., Shizuo A., Iwakura Y., Yano A.
- Journal Title
  
  Microbiol.Immunol. 48
  
  Pages: 617-628
- NAID
  10013440531
- Data Source
  KAKENHI-PROJECT-15390135
[Journal Article] IL-6, but not IL-1, induction in the brain downstream of Cox-2 is essential for the induction of febrile response against peripheral IL-1α.2004
- Author(s)
  Kagiwada, K., Chida, D., Iwakura, Y
- Journal Title
  
  Endocrinology 145
  
  Pages: 5044-5048
- Data Source
  KAKENHI-PROJECT-16043216
[Journal Article] Induction of IgG2a class switching in B cells by IL-272004
- Author(s)
  Yoshimoto, T., Iwakura, Y., Mizuguchi, J et al.
- Journal Title
  
  J.Immunol 173
  
  Pages: 2479-2485
- Data Source
  KAKENHI-PROJECT-16043216
[Journal Article] Role of Dok-1 and Dok-2 in myeloid homeostasis and suppression of leukemia.2004
- Author(s)
  Yasuda, T., Shirakata, M., Iwakura, Y., Yamanashi, Y et al.
- Journal Title
  
  J.Exp.Med 200
  
  Pages: 1681-1687
- Data Source
  KAKENHI-PROJECT-16043216
[Journal Article] Interleukin (IL)-6, but not IL-1, induction in the brain downstream of cyclooxygenase-2 is essential for the induction of febrile response against peripheral IL-1 alpha.2004
- Author(s)
  Kagiwada K, Chida D, Sakatani T, Asano M, Nambu A, Kakuta S, Iwakura Y.
- Journal Title
  
  Endocrinology 145・11
  
  Pages: 5044-5048
- Data Source
  KAKENHI-PROJECT-16046207
[Journal Article] Involvement of IL-17 in Fas ligand-induced inflammation2004
- Author(s)
  Umemura, M., Iwakura, Y., Suda, T.et al.
- Journal Title
  
  Int Immunol 16
  
  Pages: 1099-1108
- NAID
  10013425139
- Data Source
  KAKENHI-PROJECT-16043216
[Journal Article] Evaluation of the effect of sulfamethoxazole on Toxoplasma gondii loads and stage conversion in IFN-g knockout mice using QC-PCR2004
- Author(s)
  Usama S.Belal, Norose K, Aosai F, Mun H-S, Azza K.Ahmed, Chen M, Rabie M.Mohamed, Piao L-X, Iwakura Y, Yano A.
- Journal Title
  
  Microbiol.Immunol. 48(3)
  
  Pages: 185-193
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390135
[Journal Article] TNFα is crucial for the development of autoimmune arthritis in IL-1 receptor antagonist-deficient mice.2004
- Author(s)
  Horai, R., Saijo, S., Iwakura, Y.et al.
- Journal Title
  
  J.Clin.Invest 114
  
  Pages: 1603-1611
- Data Source
  KAKENHI-PROJECT-16043216
[Journal Article] TNFα is crucial for the development of autoimmune arthritis in IL-1 receptor antagonist-deficient mice.2004
- Author(s)
  Horai, R., Saijo, S., Iwakura, Y.et al.
- Journal Title
  
  J.Clin.Invest 114
  
  Pages: 1603-1611
- Data Source
  KAKENHI-PROJECT-16012209
[Journal Article] IL-6 regulates in vivo dendritic cell differentiation through STAT3 activation2004
- Author(s)
  Park S.J., Iwakura, Y., Ishihara, K., M., Hirano, T.et al.
- Journal Title
  
  J.Immunol 173
  
  Pages: 3844-3854
- Data Source
  KAKENHI-PROJECT-16012209
[Journal Article] The role of IFN-γ and toll-like receptors in nephropathy induced by Toxoplasma gondii infection.2004
- Author(s)
  Kudo M., Aosai R, Mun H-S., Norose K., Shizuo A., Iwakura Y., Yano A.
- Journal Title
  
  Microbiol.Immunol. 48
  
  Pages: 617-628
- NAID
  10013440531
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390135
[Journal Article] Role of Dok-1 and Dok-2 in myeloid homeostasis and suppression of leukemia.2004
- Author(s)
  Yasuda, T., Shirakata, M., Iwakura, Y., Yamanashi, Y et al.
- Journal Title
  
  J.Exp.Med 200
  
  Pages: 1681-1687
- Data Source
  KAKENHI-PROJECT-16012209
[Journal Article] Evaluation of the effect of sulfamethoxazole on Toxoplasma gondii loads and stage conversion in IFN-g knockout mice using QC-PCR2004
- Author(s)
  Usama S.Belal, Norose K, Aosai F, Mun H-S, Azza K.Ahmed, Chen M, Rabie M Mohamed, Piao L-X, Iwakura Y, Yano A
- Journal Title
  
  Microbiol.Immunol. 48(3)
  
  Pages: 185-193
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390135
[Journal Article] The point mutation of tyrosine 759 of the IL-6 family cytokine receptor gp130 synergizes with HTLV-1 pX in promoting rheumatoid arthritis-like arthritis2004
- Author(s)
  Ishihara, K., Sawa, S.Iwakura, Y., Hirano, T et al.
- Journal Title
  
  Int.Immunol 16
  
  Pages: 455-465
- NAID
  10013084315
- Data Source
  KAKENHI-PROJECT-16043216
[Journal Article] Involvement of IL-17 in Fas ligand-induced inflammation2004
- Author(s)
  Umemura, M., Iwakura, Y., Suda, T.et al.
- Journal Title
  
  Int Immunol 16
  
  Pages: 1099-1108
- NAID
  10013425139
- Data Source
  KAKENHI-PROJECT-16012209
[Journal Article] The role of IFN-γ and toll-like receptors in nephropathy induced by Toxoplasma gondii infection.2004
- Author(s)
  Kudo M., Aosai F., Mun H-s., Norose K., Shizuo A., Iwakura Y., Yano A.
- Journal Title
  
  Microbiol.Immunol. 48
  
  Pages: 617-628
- NAID
  10013440531
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390135
[Journal Article] 炎症、アレルギー病態におけるIL-17の役割2003
- Author(s)
  岩倉洋一郎
- Journal Title
  
  Molecular Medicine(臨時増刊号)免疫2004 40
  
  Pages: 252-258
- Data Source
  KAKENHI-PROJECT-15039206
[Journal Article] Pathogenecity of toxoplasma gondii through B-2 cell-mediated downregulation of host defense responses.2003
- Author(s)
  HYe-Seong Mun, Fumie Aosai, Mei Chen, Lian-Xun Piao, Kazumi Norose, Yoichiro Iwakura, Akihiko Yano
- Journal Title
  
  Invest.Opthalmol.Vis.Sci. 44
  
  Pages: 4375-4381
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390135
[Journal Article] Pathogenicity of Toxoplasma gondii through B-2 cell-mediated downreguiation of host defense responses.2003
- Author(s)
  Hye-Seong Mun, Fumie Aosai, Mei Chen, Lian-Xun Piao, Kazumi Norose, Yoichiro Iwakura, Akihiko Yano
- Journal Title
  
  Microbiol.Immunol. 47(7)
  
  Pages: 533-542
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390135
[Journal Article] Autoimmune chronic inflammatory arthropathy in mice transgenic for the HTLV-I tax gene.2003
- Author(s)
  Iwakura, Y.
- Journal Title
  
  Gann Monograph on Cancer Res. 50
  
  Pages: 95-109
- NAID
  50000788513
- Data Source
  KAKENHI-PROJECT-15039206
[Journal Article] The mechanism of lipopolysaccharide-induced human immunodeficiency virus type I activation in transgenic mouse macrophages.
- Author(s)
  Kadoki, M., Choi, B.I., Iwakura, Y.
- Journal Title
  
  Int. Immunol. (in press)
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] Characterization of a variant virus from ascites of subacute granulomatous serositis in interferon-g-deficient C57BL/6 mice persistently infected with murine coronavirus strain JHM.
- Author(s)
  Taguchi, F., Matsuyama, S., Iwakura, Y., Tagawa, Y., Saegusa, J., Kyuwa, S.
- Journal Title
  
  Viral Immunol. (in press)
- Data Source
  KAKENHI-PROJECT-19059006
[Journal Article] TNF, but not IL-6 and IL-17, is crucial for the development of T cell-independent psoriasis-like dermatitis in Il1rn-/- mice.
- Author(s)
  Nakajima, A., Matsuki, T., Komine, M., Asahina, A., Horai, R., Ishigame, H., Nakae, S., Kakuta, S., Saijo, S., Iwakura, Y.
- Journal Title
  
  J. Immunol. (in press)
- Data Source
  KAKENHI-PROJECT-19059006
[Patent] 乳酸菌増殖促進剤、制御性T細胞T細胞増加剤、乳酸菌増殖促進方法、制御性T細胞を増加させる方法、制御性T細胞増加効果の評価方法、および乳酸菌増殖促進効果の評価方法2018
- Inventor(s)
  岩倉洋一郎、唐策、大野尚仁
- Industrial Property Rights Holder
  岩倉洋一郎、唐策、大野尚仁
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Acquisition Date
  2018
- Data Source
  KAKENHI-PROJECT-18H02671
[Patent] 乳酸菌増殖促進剤、制御性T細胞T細胞増加剤、乳酸菌増殖促進方法、制御性T細胞を増加させる方法、制御性T細胞増加効果の評価方法、および乳酸菌増殖促進効果の評価方法2018
- Inventor(s)
  岩倉洋一郎、唐策、大野尚仁
- Industrial Property Rights Holder
  岩倉洋一郎、唐策、大野尚仁
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Acquisition Date
  2018
- Data Source
  KAKENHI-PUBLICLY-18H05045
[Patent] 抗IL－17F中和抗体の炎症性腸疾患に対する治療・予防効果2018
- Inventor(s)
  岩倉洋一郎、唐策
- Industrial Property Rights Holder
  岩倉洋一郎、唐策
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Overseas
- Data Source
  KAKENHI-PROJECT-18H02671
[Patent] 樹状細胞の成熟抑制剤及び成熟抑制方法、並びに医薬組成物2018
- Inventor(s)
  岩倉洋一郎、矢部力朗
- Industrial Property Rights Holder
  岩倉洋一郎、矢部力朗
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Data Source
  KAKENHI-PUBLICLY-18H05045
[Patent] 樹状細胞の成熟抑制剤及び成熟抑制方法、並びに医薬組成物2018
- Inventor(s)
  岩倉洋一郎、矢部力朗
- Industrial Property Rights Holder
  岩倉洋一郎、矢部力朗
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-18H02671
[Patent] 抗IL－17F中和抗体の炎症性腸疾患に対する治療・予防効果2018
- Inventor(s)
  岩倉洋一郎、唐策
- Industrial Property Rights Holder
  岩倉洋一郎、唐策
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Overseas
- Data Source
  KAKENHI-PUBLICLY-18H05045
[Patent] 樹状細胞免疫受容体活性化剤、樹状細胞免疫受容体活性化方法、破骨細胞形成抑制剤、破骨細胞形成抑制方法、樹状細胞分化・増殖阻害剤、樹状細胞分化・増殖阻害方法2014
- Inventor(s)
  岩倉洋一郎、海部知則、矢部力朗
- Industrial Property Rights Holder
  岩倉洋一郎、海部知則、矢部力朗
- Industrial Property Rights Type
  特許
- Filing Date
  2014-07-11
- Data Source
  KAKENHI-PROJECT-24220011
[Patent] 樹状細胞免疫受容体活性化剤、樹状細胞免疫受容体活性化方法、破骨細胞形成抑制剤、破骨細胞形成抑制方法、樹状細胞分化・増殖阻害剤、樹状細胞分化・増殖阻害方法。2014
- Inventor(s)
  岩倉洋一郎、海部知則、矢部力朗
- Industrial Property Rights Holder
  岩倉洋一郎、海部知則、矢部力朗
- Industrial Property Rights Type
  特許
- Filing Date
  2014-07-14
- Overseas
- Data Source
  KAKENHI-PROJECT-26430095
[Patent] CTRP3 plays an important role in the development of collagen-induced arthritis in mice.2013
- Inventor(s)
  岩倉洋一郎，村山正承
- Industrial Property Rights Holder
  東京理科大学
- Industrial Property Rights Type
  特許
- Filing Date
  2013-11-15
- Overseas
- Data Source
  KAKENHI-PROJECT-24220011
[Patent] 自己免疫疾患治療及び予防薬としてのCTRP62012
- Inventor(s)
  岩倉洋一郎，村山正承，石亀晴道，角田茂 (東京大学)
- Industrial Property Rights Holder
  岩倉洋一郎，村山正承，石亀晴道，角田茂 (東京大学)
- Industrial Property Rights Type
  特許
- Filing Date
  2012-11-22
- Overseas
- Data Source
  KAKENHI-PROJECT-24220011
[Patent] 腸疾患の治療方法および治療用医薬組成物2011
- Inventor(s)
  岩倉洋一郎、角田茂、鈴木俊佐
- Industrial Property Rights Holder
  東京大学
- Filing Date
  2011-02-02
- Overseas
- Data Source
  KAKENHI-PROJECT-20220009
[Patent] 樹状細胞免疫受容体刺激剤2011
- Inventor(s)
  岩倉洋一郎、藤門範行、馬光宇
- Industrial Property Rights Holder
  東京大学
- Filing Date
  2011-02-23

Iwakura Yoichiro 岩倉 洋一郎

IWAKURA Yoichiro 岩倉 洋一郎

岩倉 洋一朗 イワクラ ヨウイチロウ

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Analysis of inflammation, allergy, fibrosis, and tumorigenesis through the innate immune systemPrincipal InvestigatorOngoing

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Generation of gene-modified mice by targeting on innate immune receptor family and analysis of the function of these receptors by using human disease-models.Ongoing

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真菌感染現象における抑制型C型レクチン受容体の生理機能の解明Ongoing

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自然免疫受容体を介した腸管免疫の制御と全身免疫への影響の解析Principal InvestigatorOngoing

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C型レクチン受容体の生理機能の解析と疾病制御への応用Principal InvestigatorOngoing

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Elucidation of the host's homeostatic responses by the regulation of immune system and its application to the prevention and treatment of immunological disordersOngoing

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Establishment of an IL-1-related gene-manipulated mouse library and dissection of the gene-targeted mice, aiming at identifying new therapeutic targets for diseasesPrincipal Investigator

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創薬標的の探索を目指したIL-1関連遺伝子改変マウスライブラリーの作製研究Principal Investigator

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Iwakura Yoichiro 岩倉洋一郎

IWAKURA Yoichiro 岩倉洋一郎

岩倉洋一朗イワクラヨウイチロウ