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MATSUZAWA Akio
松沢 昭雄
Connect your ORCID iD
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Researcher Number
50012745
External Links
Affiliation (based on the past Project Information)
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1998 – 1999: Inst.Med.Sci., Tokyo Univ., Professor, 医科学研究所, 教授
1998: 東京大学, 医科学研究科, 教授
1998: 東京大学医科学研究所, 教授
1997 – 1998: 東京大学, 医科研, 助教授
1986 – 1997: 東京大学, 医科学研究所, 助教授
1986: 東大, 医科学研究所, 助教授
1985: 東京大学, 医科研, 助教授
Review Section/Research Field
Principal Investigator
Experimental pathology
Except Principal Investigator
General surgery
/
内科学一般
/
Experimental pathology
/
Digestive surgery
/
Laboratory animal science
/
Ophthalmology
Keywords
Principal Investigator
自己免疫病 / lpr^<cg>遺伝子 / マウス乳癌 / 進展 / リンパ節腫脹 / IV型コラーゲン / gld遺伝子 / Autoimmune disease / lpr^<cg> gene / 遺伝子治療
…
More
/ ホルモン / 自律性増殖 / 染色体異常 / ホルモン依存性 / オンコジーン / 基底膜 / マウス / 自己抗体 / Lymphadenopathy / Autoantibody / MRLマウス / 相補作用 / MRL mice / 糸球体腎炎 / スーパー抗原 / Superantigen / Gene therapy / IL-12 / 乳癌の進展 / 転移能 / intー2遺伝子 / hst遺伝子 / ケラチン / IV型コラケーナーゼ / アポトーシス / Fas / 抗Fas抗体 / lpr / gld / 肝癌 / 癌治療 / エストロジェン受容体 / 活性化 / プロジェステロン受容体 / 悪性化 / プロMMTV / 染色体 / ヘテロジェナイティー / MMTV遺伝子 / コラゲナーゼ / 肺コロニー形成能 / int-2 / hst / 全身リンパ節腫脹 / CD4^ー8^ーT細胞 / 胸腺 / 異常T細胞 / ホ-ミング / Mouse / Double-negative T cells / gld gene / Thymus / 自己免疫 / 腎炎 / ホーミング / 全身性リンパ節腫脹 / Lpr^<cg> gene / Gld gene / Autoimmunity / Nephritis / Complementation / Homing / マウスモデル / MRL背景 / コンジェニック / 血管炎 / リンパ筋腫脹 / mouse model / MRL background / autoimmunity / congenic / gromeluronephritis / artiritis / lymphadenopathy / マウス乳癌ウイルス / Vβ8.2T細胞 / 1pr^<cg>遺伝子 / Mammary tumor virus / Vbeta8.2+ T cells / Lymphoproliferation / lpr^<cg>マウス / CD4T細胞 / IL-12p40 / 1pr^<cg>マウス / IL-1 / CD4欠損変異 / 可溶性CD4 / 免疫複合体 / MRL-lprィイD1cgィエD1 mice / Glomerulonephritis / Lympadenopathy / 腎臓 / 初期発生 / 遺伝性白内障 / 水晶体 / ホルモン依存性乳癌 / 自律性獲得 / 転移 / 【IV】型コラーゲン / マウス腎臓 / マウス初期発生 / コンパクション / Basement membrane / type IV collagen / mice / kidney / early development / hereditary cataract / lens / autoimmune disease / hormone-dependent mammary tumor
…
More
Except Principal Investigator
自己免疫 / マウス乳癌 / アポトーシス / lpr / gld / 浸潤 / Fas / HIV / gp120 / 自己免疫病 / lpr^<cg> gene / ホルモン依存性 / 自律性増殖 / 細胞間相互作用 / 悪性度 / コラーゲンゲル / ヘテロジェナイテイ / Mouse mammary tumor / Heterogenity / Hormone-dependency / Autonomous growth / Tumor-cell / cell interactions / Malignancy / Collagen gel / LMFS / HCFU / ND2001 / p-53 / point mutation / Retinitis pigmentosa / nitrosomethylurea / apoptosis / lpr^<cg> / リンパ節腫脹 / 転移 / lprcg / ヘテロ接合 / DN細胞 / ホーミング / Myc / アデノウイルスE1A / 制がん剤 / Bax / FasL / アポトーシスシグナル / カスパーゼ3様プロテアーゼ / アポトーシス耐性 / LPS / Pim-1キナーゼ / リンパ腫 / ICE / CED-3 family proteases / myc関連遺伝子 / エンドトキシンLPS / トポイソメラーゼIIα / アポトーシスエンドヌクレアーゼ / 乳癌ウイルス / スンクス乳癌 / ラット乳癌 / ヒト乳癌 / ヒト乳癌抗原 / 妊娠依存性乳癌 / MMTV / MMTVゲノム / 乳癌抑制遺伝子 / 乳癌前癌病変 / MMTVの定量法 / MMTV-LTR / 白内障 / 遺伝性白内障マウス / NAKANOマウス / 白内障モデル / 戻し交配 / 白内障遺伝子 / 白内障発症機構 / 水晶体蛋白 / 1pr^<cg>遺伝子 / イディオタイプネットワーク / 自己免疫マウス / 抗gp120抗体 / autoimmunity / idiotype network / ヘテロジェナィティ / アクチノニン / ヘテロジェナイティ / 肺転移能 / アクチノーン / 自律性進展 / Actinonin / 糸球体腎炎 / lpr^<cg>遺伝子 / MRLマウス / マウス乳癌ウイルス / スーパー抗原 / レトロウイルス / VB8.2 / autoimmune disease / glomerlonehritis / MRL mouse / mouse mammary tumor virus / superantigen / 自然肝転移 / 転移抑制 / 化学療法 / spontaneous liver metastasis / Inhibition of metastasis / chemotherapy / トランスジェニックマウス / ノックアウトマウス / IL-1α / IL-1β / IFN-γ / IL-6 / HTLV-I / 関節リウマチ / IL-1レセプターアンタゴニスト / HTLV-L Tgマウス / HIV-Tgマウス / HTLV-I Tgマウス / IL-12 / HTLV-I-Tgマウス / HIV-I-Tgマウス / メタロチオネイン / Methallotionein / Photoreceptor cell / 網膜変性 / 網膜異形成 / ロゼット / 色素性網膜変性症 / ニトロソ尿素 / 視細胞 / 実験動物 / 色素上皮細胞 / photoreceptor cell / retinal degeneration / pigment epithelial cell / retinal dysplasia / rosette / 癌遺伝子治療 / Fas-FasLシステム / マウス肝癌 / Cancer gene therapy / FasL system / Apoptosis / Murine hepatoma / Murine mammary tumor
Less
Research Projects
(
25
results)
Co-Researchers
(
40
People)
Project Start Year (Newest)
Project Start Year (Oldest)
Elucidation of the mechanism how Vβ T cells aggravate autoimmune diseases and establishment of T cell receptor (TCR)-targeted gene therapies of autoimmune diseases
Principal Investigator
Principal Investigator
TAMURA Toshiki
, 松澤 昭雄
Project Period (FY)
1998 – 1999
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Experimental pathology
Research Institution
The University of Tokyo
A study for cancer gene therapy through Fas-mediated apoptosis
Principal Investigator
TAKEDA Yasutaka
Project Period (FY)
1998 – 1999
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
General surgery
Research Institution
The University of Tokyo
Comparative pathological study of human retinitis pigmentosa and its animal models
Principal Investigator
TSUBURA Airo
Project Period (FY)
1997 – 1998
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Ophthalmology
Research Institution
Kansai Medical University
アポトーシス機構の解析とその発がん、制がん研究への応用
Principal Investigator
口野 嘉幸
Project Period (FY)
1996 – 1998
Research Category
Grant-in-Aid for Scientific Research on Priority Areas (A)
Research Institution
National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
サイトカイン研究のための遺伝子改変マウスライブラリーの作製
Principal Investigator
岩倉 洋一郎
Project Period (FY)
1996 – 1998
Research Category
Grant-in-Aid for Scientific Research (A)
Research Field
Laboratory animal science
Research Institution
The University of Tokyo
Amelioration of lpr^<cg>-induced autoimmune diseases with Vbeta8.2-specific viral superantigen and its application to gene therapy in mice
Principal Investigator
Principal Investigator
MATSUZAWA Akio
Project Period (FY)
1996 – 1997
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Experimental pathology
Research Institution
The University of Tokyo
A study on tumor cell/cell interactions using mouse mammary tumor models
Principal Investigator
TAKEDA Yasutaka
Project Period (FY)
1996 – 1997
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
General surgery
Research Institution
The University of Tokyo
FAS-FASリガンド実験系を用いたアポトーシスによる癌治療の基礎的研究
Principal Investigator
Principal Investigator
松澤 昭雄
Project Period (FY)
1995
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
The University of Tokyo
Analysis and murine atoimmune disease utilizing a superantigen possessed by a retrovirus.
Principal Investigator
KIMURA Mikio
Project Period (FY)
1995 – 1996
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
内科学一般
Research Institution
The University of Tokyo
INVESTIGATION OF SPONTANEOUS LIVER METASTASIS MODEL OF BALB/c REIROPERITONEAL SARCOMA (LMFS) AND CLINICAL APPLICATION
Principal Investigator
FUJII Yuzo
Project Period (FY)
1995 – 1996
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Digestive surgery
Research Institution
The University of Tokyo
Elucidation of properties and mechanism of development of autoimmune diseases in new congenic MRL/MpJ-lprcg/lprcg mice
Principal Investigator
Principal Investigator
MATSUZAWA Akio
Project Period (FY)
1994 – 1995
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Experimental pathology
Research Institution
The University of Tokyo
Study of Tumor Progression in vivo and in vitro using
Principal Investigator
TAKEDA Yasutaka
Project Period (FY)
1994 – 1995
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
General surgery
Research Institution
The University of Tokyo
Role of anti-HIV-gp120 antibody in the lpr^<cg> and other autoimmune mice.
Principal Investigator
KIMURA Mikio
Project Period (FY)
1993 – 1994
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
内科学一般
Research Institution
The University of Tokyo
lprcg、lpr及びgld異常リンパ球のリンパ節浸潤、転移機構の解明
Principal Investigator
木村 幹男
Project Period (FY)
1992
Research Category
Grant-in-Aid for Cancer Research
Research Institution
The University of Tokyo
Studies on background genes aggravating lpr^<cg>-induced nephritis and complementation between lpr^<cg> and gld genes
Principal Investigator
Principal Investigator
MATSUZAWA Akio
Project Period (FY)
1992 – 1993
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Experimental pathology
Research Institution
The University of Tokyo
lpr^<cg>,lpr及びgld異常リンパ球のリンパ節浸潤、転移機構の解明
Principal Investigator
KIMURA Mikio
Project Period (FY)
1991
Research Category
Grant-in-Aid for Cancer Research
Research Institution
The University of Tokyo
Studies on the Mechanism of Induction of Autoimmune Disease by the Novel Lymphoproliferation gene, lpr^<cg>
Principal Investigator
Principal Investigator
MATSUZAWA Akio
Project Period (FY)
1990 – 1991
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Experimental pathology
Research Institution
Institute of Medical Science, University of Tokyo
ホルモン依存性乳癌の進展とヘテロジェナィティー
Principal Investigator
Principal Investigator
松沢 昭雄
Project Period (FY)
1989
Research Category
Grant-in-Aid for Cancer Research
Research Institution
The University of Tokyo
ホルモン依存性乳癌の進展とヘテロジェナイティー
Principal Investigator
Principal Investigator
松沢 昭雄
Project Period (FY)
1988
Research Category
Grant-in-Aid for Cancer Research
Research Institution
The University of Tokyo
ホルモン依存性乳癌の進展とヘテロジェナイティー
Principal Investigator
Principal Investigator
松沢 昭雄
Project Period (FY)
1987
Research Category
Grant-in-Aid for Cancer Research
Research Institution
The University of Tokyo
白内障発生における遺伝子発現に及ぼす宿主因子の影響
Principal Investigator
和田 栄子
Project Period (FY)
1987
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Experimental pathology
Research Institution
The University of Tokyo
ホルモン依存性乳癌の自律増殖能獲得機構の解明
Principal Investigator
Principal Investigator
松沢 昭雄
Project Period (FY)
1986
Research Category
Grant-in-Aid for Cancer Research
Research Institution
The University of Tokyo
マウス乳癌ウイルス(MMTV)を中心とする各種動物の乳癌発生機構の比較解析
Principal Investigator
星野 宗光
Project Period (FY)
1986
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Nagoya University
Studies on the roles of collagens in cell proliferation and differentiation, tissue organization, and pathological changes
Principal Investigator
Principal Investigator
MATSUZAW akio
Project Period (FY)
1986 – 1987
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Experimental pathology
Research Institution
Institute of Medical Science, University of Tokyo
ホルモン依存性乳癌の自律増殖能獲得機構の解明
Principal Investigator
Principal Investigator
松沢 昭雄
Project Period (FY)
1985
Research Category
Grant-in-Aid for Cancer Research
Research Institution
The University of Tokyo
# of Projects (Dsc)
# of Projects (Asc)
1.
KIMURA Mikio
(90114462)
# of Collaborated Projects:
9 results
# of Collaborated Products:
0 results
2.
TSUBURA Airo
(90098137)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
3.
KATAGIRI Takuya
(70126100)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
4.
村上 昭
(50127148)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
5.
YOSHIMOTO Takayuki
(80202406)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
6.
TAKEDA Yasutaka
(40163422)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
7.
及川 勉
(40120141)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
8.
SHIMIZU Motomu
(10124463)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
9.
WATANABE Tomomasa
(10100174)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
10.
NARIUCHI Hideo
(10012741)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
11.
TAMURA Toshiki
(40291306)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
12.
IKEDA Hidetoshi
(60101119)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
13.
WAKABAYASHI Tomo
(90092379)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
14.
FUJII Yuzo
(40143515)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
15.
YANAGIE Hironobu
(30212278)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
16.
MORI Shigero
(30010424)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
17.
SAYAMA Kazutoshi
(30260582)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
18.
MIKI Hirohiko
(30077771)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
19.
SENZAKI Hideto
(10206659)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
20.
NAKANO Hideki
(30266928)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
21.
TANAKA Shin
(70134624)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
22.
口野 嘉幸
(60124418)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
23.
中島 琢磨
(90256678)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
24.
田沼 靖一
(10142449)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
25.
三浦 正幸
(50202338)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
26.
藤田 直也
(20280951)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
27.
堂福 隆一
(50099975)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
28.
岩口 孝雄
(40085634)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
29.
星野 宗光
(10073107)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
30.
土田 信夫
(60089951)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
31.
今井 俊介
(10075038)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
32.
大野 典也
(60147288)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
33.
田中 春高
(10027310)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
34.
和田 栄子
(70114725)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
35.
保田 立二
(30092357)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
36.
岩倉 洋一郎
(10089120)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
37.
須藤 カツ子
(50126091)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
38.
浅野 雅秀
(50251450)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
39.
田川 陽一
(70262079)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
40.
SAEGUSA Yoshiyuki
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
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