Yoshimoto Takayuki 善本隆之

… Alternative Names

Researcher Number	80202406
Other IDs
Affiliation (Current)	2021: 東京医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2008 – 2019: Tokyo Medical University, 医学部, 教授 2002 – 2008: 東京医科大学, 医学部, 助教授 2007: 兵庫医科大学, 医学部, 准教授 2007: Tokyo Medical University, 医学部, 准教授 2002 – 2003: 東京医科大学, 難病治療研究センター, 助教授 … More
Review Section/Research Field	Principal Investigator Immunology / Biological Sciences / Functional biochemistry / Kidney internal medicine / Hematology / Basic Section 43030:Functional biochemistry-related Except Principal Investigator Dermatology / Experimental pathology / General surgery / Experimental pathology … More
Keywords	Principal Investigator IL-12 / IFN-γ / IL-27 / NO / NK細胞 / MHC Class II / CD28 / CTLA-4 / STAT1 / STAT3 … More Except Principal Investigator IL-27 / IL-12 / アポトーシス / サイトカイン / 乾癬 / 樹状細胞 / Fas / IL-23 / 精子形成 / マクロファージ / T細胞亜集団 / 細胞傷害性T細胞 / 抗Fas抗体 / 遺伝子治療 / 遺伝子導入 / トランスジェニックマウス / 免疫学 / 抗腫瘍作用 / 悪性黒色腫 / IL-22 / IL-17 / マウス / 精巣 / 抗がん剤 / 抗腫瘍効果 / 樹状細胞前駆細胞 / 炎症 / TNF / Cytokine / 自己免疫病 / スーパー抗原 / lpr^<cg>遺伝子 / リンパ節腫脹 / Autoimmune disease / Superantigen / Gene therapy / IL-12p35 / IL-12p40 / B7 / CD28 / CD152 / 自己抗体 / がん遺伝子療法 / Apoptosis / IAP(inhibitor of apoptosis protein) / Smac(second mitochondria-derived activator of caspase) / apoptosis / TRAIL / EBI3 / 抗癌治療 / 漢方薬 / 間葉系幹細胞 / ヘルパーT細胞 / 第二シグナル / IL-2受容体 / シグナル伝達経路 / ナイーブとメモリー / 遺伝子構造 / IL-12産生 / CD40-CD40L / Th1 / Th2 / IL-10 / B7分子 / IL-12遺伝子 / 移植腫瘍 / 免疫記憶 / lpr / gld / 肝癌 / 癌治療 / Fas-FasL反応 / IL-12遺伝子導入腫瘍 / IRES / IL-12p40トランスジェニックマウス / 肝転移モデル / 原虫感染 / 蠕虫感染 / 生体防御 / IL-33 / 癌 / インターロイキン27 / 血管新生阻害 / インターロイン27 / 血管新生阻害作用 / Notch / 精子幹細胞 / 異種移植 / 免疫寛容 / 移植 / 免疫抑制 / ミエロイド系前駆細胞 / 細胞療法 / インターフェロン / Tヘルパー細胞亜集団 / 腫瘍壊死因子 / 内毒素 / 炎症反応 / インターロイセン1 / Inflammation / Tumor necrosis factor / Interferon / T helper cell subset / マウス乳癌ウイルス / Vβ8.2T細胞 / MRLマウス / 1pr^<cg>遺伝子 / lpr^<cg> gene / Mammary tumor virus / Vbeta8.2+ T cells / MRL mice / Lymphoproliferation / MHCクラスII / IL-12非依存性Th1分化 / IL-12受容体 / IL-12Rβ2 / B7刺激 / 副刺激 / T細胞抗原受容体 / T細胞上B7-2発現 / IL-2p40 / MHC class II / IL-12 independent TH1 differentiation / lpr^<cg>マウス / 糸球体腎炎 / CD4T細胞 / 1pr^<cg>マウス / IL-1 / CD4欠損変異 / 可溶性CD4 / 免疫複合体 / MRL-lprィイD1cgィエD1 mice / Glomerulonephritis / Lympadenopathy / Autoantibody / Fasリガンド発現腫瘍 / 非ウイルス性ベクター / リポソーム / 抗腫瘍免疫 / ケモカイン / Fasリガンド / 好中球 / FasL(CD95L)-transfected tumor cell / Cancer Gene therapy / Nonviral vector / Gene delivery / Liposome / Anti-tumor effect / Chemokine / TNFα / 肝細胞 / Smac(second mitochondria-derived activator of caspases) / TNF-α / hepatocyte / 耐性 / 耐性腫瘍の出現頻度 / cDNA欠落 / cDNAメチル化 / DNA欠落 / DNAメチル化 / 抗体療法 / Cancer gene therapy / Resistant cells / Mutation frequency / cDNA depletion / cDNA methylation / anti-Fas mAb / 化学療法剤 / 口腔扁平上皮癌 / 新規治療法 / Bcl-2ファミリータンパク質 / 化学療法剤抵抗性 / Bcl2ファミリータンパク質 / カルボプラチン / 難治性悪性腫瘍 / Bax-α / 併用療法 / chemotherapeutic agents / squamous cell carcinoma / new treatment modality / Bcl-2 family proteins / 乳癌 / 骨転移 / 肝細胞増殖因子 / mammary cancer / bone metastasis / hepatocyte growth factor / IL-23Ra / カルネキシン / IL-23R / 腸炎 / p19 / heterodimeric cytokine / 液性因子 / 細胞因子 / 放射線 / セルトリ細胞 / 抗癌剤 / T細胞 / Dendritic Cells / naive Th Cells / ASK1 / イミキモド角化細胞 / 分化 / 尋常性乾癬 / IMQ / IL-22 蛋白 / p38 / 発現制御 / 細胞・組織 / シグナル伝達 / 血管成長因子 / ケモタキシス / Th17 / 急性脳症 / てんかん / 新規抗てんかん薬 / 機能性ナノ磁気微粒子 / モデルマウス / 脳保護 / フローサイトメトリー / 脳症 / プレコンディショニング / 肺線維症 / 免疫調節 / IL-35 / 再生医学 / 移植・再生医療 / がん治療応用 / 骨髄由来免疫抑制細胞 / 動物実験代替法 / 感作性 / アレルギー / 化学物質 / 呼吸器感作性 / 3次元共培養系 / 放射線療法 / 不妊症 / 樹状細胞前駆細胞株 / iPS細胞 / iPS Less

A novel mechanism whereby EBI3, one of IL-27 cytokine subunits, augments target protein expression under inflammatory conditionsPrincipal InvestigatorOngoing
- Principal Investigator
  
  善本隆之
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Tokyo Medical University
Oncofertility視点に基づく若年癌患者の性腺機能不全の漢方治療法の確立Ongoing
- Principal Investigator
  
  曲寧
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Tokai University
Development of a novel method to generate human iPS cell-derived dendritic cell progenitors and their effectivenessOngoing
- Principal Investigator
  
  米戸敏彦
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Tokyo Medical University
Inhibition of pulmonary fibrosis by mesenchymal stem cells through IL-27 and its clinical applicationOngoing
- Principal Investigator
  
  田口紋子
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Tokyo Medical University
Comprehensive study on IL-27, one of the IL-12 family cytokines, aiming at its clinical application for cancer immunotherapyOngoing
- Principal Investigator
  
  徐明利
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Tokyo Medical University
Development of a novel alternative to animal testing for the evaluation of respiratory allergic sensitizing potential of chemicalsOngoing
- Principal Investigator
  
  溝口出
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 63030:Chemical substance influence on environment-related
- Research Institution
  Tokyo Medical University
Therapeutic effect of mesenchymal stem cells by anti-inflammatory cytokinesIL-27 and IL-35
- Principal Investigator
  
  OWAKI Toshiyuki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kyushu University
  Tokyo Medical University
Elucidation of the mechanism of action of novel antiepileptic drugs using functionalized magnetic nanoparticles and exploration of their neuroprotective effects
- Principal Investigator
  
  Yamanaka Gaku
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Tokyo Medical University
A novel role for EBI3, a common subunit of IL-27 and IL-35, as a intracellular molecule in the augmentation of IL-23Ra protein expression
- Principal Investigator
  
  Mizoguchi Izuru
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokyo Medical University
Identification and functional analysis of a novel IL-6/IL-12 family cytokine
- Principal Investigator
  
  Xu Mingli
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Tokyo Medical University
The effect of traditional medicine on busulfan- and/or irradiation-induced aspermatogenesis
- Principal Investigator
  
  QU Ning
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  Tokai University
  Tokyo Medical University
Proliferation and Differentiation of naive helper T cells by Dendritic cells in Human
- Principal Investigator
  
  NAGAI Taro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Tokyo Medical University
Regulation of the development of psoriasis by ASK1, a stress-responsive MAP kinase
- Principal Investigator
  
  Okubo Yukari
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Tokyo Medical University
IL-27により分化誘導したDC前駆細胞を用いた新しい癌DCワクチン療法の開発
- Principal Investigator
  
  久田将之
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General surgery
- Research Institution
  Tokyo Medical University
IL-27による造血幹細胞の運命決定メカニズムの解明Principal Investigator
- Principal Investigator
  
  善本隆之
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical University
The roles and applications of IL-23 and IL-27 in new therapeutic strategies for malignant melanoma and psoriasis
- Principal Investigator
  
  NAGAI HIROSHI
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Kobe University
Induction of IL-17-producing T cells by VEGF-A as starting molecule: Paradigm shift of psoriasis pathogenesis.
- Principal Investigator
  
  Tokura Yoshiki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Dermatology
- Research Institution
  Hamamatsu University School of Medicine
Study on the regulation of immune responses by a novel IL-6/IL-12 family cytokinePrincipal Investigator
- Principal Investigator
  
  YOSHIMOTO Takayuki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tokyo Medical University
Establishment of the differentiation method to spermatogenesis by the xenogeneic transplantation of spermatogonia stem cells and the in vitro culture
- Principal Investigator
  
  Qu Ning
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Tokyo Medical University
Development of a new cancer immunotherapy with dendritic cells and macrophages by IL-27
- Principal Investigator
  
  HISADA Masayuki
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General surgery
- Research Institution
  Tokyo Medical University
New mechanism whereby IL-23 regulates immune responses through Notch signalling
- Principal Investigator
  
  XU Mingli
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Keio University
  Tokyo Medical University
Basic studies on therapeutic utilities ofIL-27 for malignant melanoma, psoriasis and alopecia areata.
- Principal Investigator
  
  NAGAI Hiroshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Kobe University
Immune regulation by the IL-6/IL-12 family cytokinesPrincipal Investigator
- Principal Investigator
  
  YOSHIMOTO Takayuki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tokyo Medical University
Analysis of mechanisms of the host defense against parasite infection by new cytokines (IL-27, IL-33)
- Principal Investigator
  
  YOSHIMOTO Tomohiro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Parasitology (including Sanitary zoology)
- Research Institution
  Hyogo College of Medicine
Analysis of antitumor effect by antiangiogenic activity of interleukin-27
- Principal Investigator
  
  SHIMIZU Motomu
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
新しいIL-6/12関連サイトカインIL-27による造血幹細胞の増殖・分化の制御Principal Investigator
- Principal Investigator
  
  善本隆之
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  Tokyo Medical University
Study of roles of bone microenvironment and immune system in establishment and progression of bone metastasis
- Principal Investigator
  
  ONO Katsuhiro
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Josai International University
Therapeutic Strategy for Squamous Cell Carcinoma Resistant to Chemotherapeutic Agents
- Principal Investigator
  
  MIZUGUCHI Junichiro
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Tokyo Medical University
Studies on the signal transduction passways through IL-12 receptorPrincipal Investigator
- Principal Investigator
  
  YOSHIMOTO Takayuki
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Tokyo Medical University
Activation of Caspases via the Mitochondrial Pathway in Hepatocyte Apoptosis -Roles of IAPs and Smac-
- Principal Investigator
  
  NAGOSHI Sumiko
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Saitama Medical School
Basic study for Analysis of Intractable Resistant Tumor Cells and their Overcoming in Cancer Gene Therapy
- Principal Investigator
  
  TAKEDA Yasutaka
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  The University of Tokyo
Clinical Application of Tumor-specific Anti-tumor Immunity Induced by Tumor Cells Expressing Fas (CD95) Ligand
- Principal Investigator
  
  TAKEDA Yasutaka
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  The University of Tokyo
Th1反応における情報伝達制御機構の解明-IL-12Rを介したIFN-γ産生へのシグナル伝達-Principal Investigator
- Principal Investigator
  
  善本隆之
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical University
マラリア感染に対する防御免疫機構-赤内型P.berghel強毒株NK65とその弱毒株XATを用いた解析-Principal Investigator
- Principal Investigator
  
  善本隆之
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  The University of Tokyo
免疫機能低下の機構解明Principal Investigator
- Principal Investigator
  
  善本隆之
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Studies on the regulation of IL-12 expression and function and its application to therapyPrincipal Investigator
- Principal Investigator
  
  YOSHIMOTO Takatyuki
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Tokyo Medical University
  The University of Tokyo
マラリア感染における防御免疫機構の研究-赤内型P.berghei強毒株NK65とその弱毒株XATを用いた検討-Principal Investigator
- Principal Investigator
  
  善本隆之
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  The University of Tokyo
Elucidation of the mechanism how Vβ T cells aggravate autoimmune diseases and establishment of T cell receptor (TCR)-targeted gene therapies of autoimmune diseases
- Principal Investigator
  
  TAMURA Toshiki, 松澤昭雄
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  The University of Tokyo
IL-12遺伝子導入腫瘍を用いた抗腫瘍効果機序の基礎的研究
- Principal Investigator
  
  成内秀雄
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
IL-12の発現調節及び作用機序に関する基礎的研究Principal Investigator
- Principal Investigator
  
  善本隆之
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Immunology
- Research Institution
  The University of Tokyo
Study on the role of IL-12 in protective immunity against infectionPrincipal Investigator
- Principal Investigator
  
  YOSHIMOTO Takayuki
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  Immunology
- Research Institution
  The University of Tokyo
Elucidation of T cell subset Th1 differentiation by IL-12
- Principal Investigator
  
  NARIUCHI Hideo
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  The University of Tokyo
IL-12遺伝子をもちいた癌免疫療法開発の基礎的研究
- Principal Investigator
  
  成内秀雄
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
IL-12による弱毒化マラリア原虫のワクチン効果増強に関する基礎的研究Principal Investigator
- Principal Investigator
  
  善本隆之
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
IL-12の発現調節機構に関する基礎的研究Principal Investigator
- Principal Investigator
  
  善本隆之
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Immunology
- Research Institution
  The University of Tokyo
Amelioration of lpr^<cg>-induced autoimmune diseases with Vbeta8.2-specific viral superantigen and its application to gene therapy in mice
- Principal Investigator
  
  MATSUZAWA Akio
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  The University of Tokyo
T細胞亜集団による免疫制御の分子機構
- Principal Investigator
  
  成内秀雄
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
IL-12遺伝子をもちいた癌免疫療法開発の基礎的研究
- Principal Investigator
  
  成内秀雄
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
FAS-FASリガンド実験系を用いたアポトーシスによる癌治療の基礎的研究
- Principal Investigator
  
  MATSUZAWA Akio
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
マウスインターロイキン12 (IL-12)の遺伝子構造及びその発現調節機構の解析Principal Investigator
- Principal Investigator
  
  善本隆之
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Immunology
- Research Institution
  The University of Tokyo
T細胞亜集団による免疫制御の分子機構
- Principal Investigator
  
  成内秀雄
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
レトロウイルス感染による自己免疫疾患誘導の機構解明Principal Investigator
- Principal Investigator
  
  善本隆之
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Immunology
- Research Institution
  The University of Tokyo
T細胞亜集団による免疫制御の分子機構
- Principal Investigator
  
  NARIUCHI Hideo
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
先天性アミノ酸尿症の原因としてのヒト塩基性アミノ酸トランスポーターの同定Principal Investigator
- Principal Investigator
  
  善本隆之
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokyo
Analysis of cytokine cascade in inflammatory reaction and application for the regulation
- Principal Investigator
  
  NARIUCHI Hideo
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  内科学一般
- Research Institution
  The University of Tokyo

[Book] Cytokine Frontiers: Regulation of Immune Responses in Health and Disease.2013
- Author(s)
  Yoshimoto, T. and Yoshimoto, T (Editors)
- Total Pages
  396
- Publisher
  Springer
- Data Source
  KAKENHI-PUBLICLY-25118727
[Book] Cytokine Frontiers: Regulation of Immune Responses in Health and Disease.2013
- Author(s)
  Yoshimoto, T. and Yoshimoto, T. (Editors)
- Total Pages
  396
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-24370058
[Book] 免疫学コア講義改訂第2版(木本雅夫、坂口薫雄、山下優毅編集)2007
- Author(s)
  善本知広
- Total Pages
  295
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-19390121
[Book] 自己免疫疾患とアレルギー.免疫学コア講義 (木本雅夫、坂口薫雄、山下優毅編集)、改訂第2版2007
- Author(s)
  善本知広
- Total Pages
  9
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-19390121
[Journal Article] Necroptosis of intestinal epithelial cells induces type 3 innate lymphoid cell-dependent lethal ileitis2019
- Author(s)
  Shindo R, Ohmuraya M, Komazawa-Sakon S, Miyake S, Deguchi Y, Yamazaki S, Nishina T, Yoshimoto T, Kakuta S, Koike M, Uchiyama Y, Konishi H, Kiyama H, Mikami T, Moriwaki K, Araki K, Nakano H.
- Journal Title
  
  iScience
  
  Volume: 15 Pages: 536-551
- DOI
  10.1016/j.isci.2019.05.011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07333, KAKENHI-PROJECT-18K11658, KAKENHI-PROJECT-19K06570, KAKENHI-PROJECT-19K06904, KAKENHI-PROJECT-19K07516, KAKENHI-PROJECT-19K08405, KAKENHI-PROJECT-19K09105, KAKENHI-PROJECT-17H04069, KAKENHI-PROJECT-17K08522, KAKENHI-PROJECT-17K08994
[Journal Article] Plasmacytoid dendritic cells protect against immune-mediated acute liver injury via IL-352019
- Author(s)
  Koda Y, Nakamoto N, Chu P, Ugamura A, Teratani T, Shiba S, Taniki N, Sujino T, Miyamoto K, Mikami Y, Suzuki T, Yamaguchi A, Morikawa R, Sato K, Yoshimoto T, Kanai K.
- Journal Title
  
  Journal of Clinical Investigation
  
  Volume: 129(8) Pages: 3201-3213
- DOI
  10.1172/jci125863
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07333, KAKENHI-PROJECT-18K08014, KAKENHI-PROJECT-18K11658, KAKENHI-PROJECT-19K06570, KAKENHI-PROJECT-19K09105, KAKENHI-PROJECT-19K22624, KAKENHI-PROJECT-18K15794
[Journal Article] Protective effects against tumors and infection by IL-27 through promotion of expansion and differentiation of hematopoietic stem cells into myeloid progenitors.2018
- Author(s)
  Orii N, Mizoguchi I, Chiba Y, Hasegawa H, Ohashi M, Xu M, Nagai T, Ochiai M, Mochizuki Y, Owaki T, Yoshimoto T.
- Journal Title
  
  Oncoimmunology
  
  Volume: -
- DOI
  10.1080/2162402x.2017.1421892
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11030, KAKENHI-PROJECT-15K07947, KAKENHI-PROJECT-15K08433, KAKENHI-PROJECT-18K07333, KAKENHI-PROJECT-18K11658
[Journal Article] Interleukin-27 Exerts Its Antitumor Effects by Promoting Differentiation of Hematopoietic Stem Cells to M1 Macrophages2018
- Author(s)
  Chiba Y, Mizoguchi I, Furusawa J, Hasegawa H, Ohashi M, Xu M, Owaki T, Yoshimoto T.
- Journal Title
  
  Cancer Research
  
  Volume: 78 Pages: 182-194
- DOI
  10.1158/0008-5472.can-17-0960
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11030, KAKENHI-PROJECT-16J04160, KAKENHI-PROJECT-15K07947, KAKENHI-PROJECT-15K08433, KAKENHI-PROJECT-18K07333, KAKENHI-PROJECT-18K11658
[Journal Article] Two cases of extremely rare primary pure squamous cell carcinoma of the breast.2018
- Author(s)
  Yoneto T, Hasumi K, Yoshimoto T, Takahashi N, Takeda Y.
- Journal Title
  
  Medicine (Baltimore)
  
  Volume: 97(37)
- DOI
  10.1097/md.0000000000012340
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11658
[Journal Article] Regulation of myelopoiesis by proinflammatory cytokines in infectious diseases2018
- Author(s)
  Chiba Y, Mizoguchi I, Hasegawa H, Ohashi M, Orii N, Nagai T, Sugahara M, Miyamoto Y, Xu M, Owaki T, Yoshimoto T.
- Journal Title
  
  Cellular and Molecular Life Sciences
  
  Volume: 75 Pages: 1363-1376
- DOI
  10.1007/s00018-017-2724-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11030, KAKENHI-PROJECT-16J04160, KAKENHI-PROJECT-15K07947, KAKENHI-PROJECT-15K08433, KAKENHI-PROJECT-18K07333, KAKENHI-PROJECT-18K11658
[Journal Article] Prediction of chemical respiratory and contact sensitizers by OX40L expression in dendritic cells using a novel 3D co-culture system.2017
- Author(s)
  Mizoguchi I, Ohashi M, Chiba Y, Hasegawa H, Xu M, Owaki T, Yoshimoto T.
- Journal Title
  
  Front. Immunol.
  
  Volume: 8 Pages: 929-929
- DOI
  10.3389/fimmu.2017.00929
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11030, KAKENHI-PROJECT-15K07947, KAKENHI-PROJECT-15K08433
[Journal Article] Promotion of expansion and differentiation of hematopoietic stem cells by interleukin-27 into myeloid progenitors to control infection in emergency myelopoiesis.2016
- Author(s)
  Furusawa J-I, Mizoguchi I, Chiba Y, Hisada M, Kobayashi F, Yoshida H, Nakae S, Tshuchida A, Matsumoto T, Ema H, Mizuguchi J, Yoshimoto T
- Journal Title
  
  PLoS Pathog.
  
  Volume: 12
- DOI
  10.1371/journal.ppat.1005507
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K08451, KAKENHI-PROJECT-16J04160, KAKENHI-PROJECT-15K07947, KAKENHI-PROJECT-15K08433
[Journal Article] Expanding diversity in molecular structures and functions of the IL-6/IL-12 heterodimeric cytokine family.2016
- Author(s)
  Hasegawa Hideaki, Izuru Mizoguchi, Yukino Chiba, Mio Ohashi, Mingli Xu, and Takayuki Yoshimoto
- Journal Title
  
  Front. Immunol.
  
  Volume: -
- DOI
  10.3389/fimmu.2016.00479
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16J04160, KAKENHI-PROJECT-15K07947, KAKENHI-PROJECT-15K08433
[Journal Article] IL-17A-producing CD30+ Vδ1 T cells drive inflammation-induced cancer progression2016
- Author(s)
  Kimura Y, Nagai N, Tsunekawa N, Sato-Matsushita M, Yoshimoto T, Cua DJ, Iwakura Y, Yagita H, Okada F, Tahara H, Saiki I, Irimura T, Hayakawa Y.
- Journal Title
  
  Cancer Sci
  
  Volume: 107 Pages: 1106-1214
- DOI
  10.1111/cas.13005
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-15J11569, KAKENHI-PROJECT-25293011, KAKENHI-PROJECT-26290059, KAKENHI-PROJECT-26430158, KAKENHI-PROJECT-26460472, KAKENHI-PROJECT-15K07947, KAKENHI-PROJECT-15K08433, KAKENHI-PROJECT-15K08902, KAKENHI-PROJECT-26670023
[Journal Article] 炎症疾患におけるTh17関連サイトカインIL-17，IL-22，IL-23の役割2015
- Author(s)
  徐明利、曲寧、溝口出、古澤純一、千葉祐規乃、伊藤正裕、善本隆之
- Journal Title
  
  炎症と免疫
  
  Volume: 23(2) Pages: 66-72
- Data Source
  KAKENHI-PROJECT-24590243
[Journal Article] Therapeutic potential of interleukin-27 against cancers in preclinical mouse models.2015
- Author(s)
  Mizoguchi, I., Chiba, Y., Furusawa, J., Xu, M., Tsunoda, R., Higuchi, K., and Yoshimoto,
- Journal Title
  
  Oncoimmunology
  
  Volume: 4(10)
- DOI
  10.1080/2162402x.2015.1042200
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K07947, KAKENHI-PROJECT-15K08433
[Journal Article] Potential clinical application of interleukin-27 as an antitumor agent.2015
- Author(s)
  Yoshimoto, T., Chiba, Y., Furusawa, J., Xu, M., Tsunoda, R., Higuchi, K., and Mizoguchi, I.
- Journal Title
  
  Cancer Sci.
  
  Volume: 106(9) Pages: 1103-1110
- DOI
  10.1111/cas.12731
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K07947, KAKENHI-PROJECT-15K08433
[Journal Article] 炎症疾患におけるTh17関連サイトカインIL-17，IL-22，IL-23の役割2015
- Author(s)
  徐明利、曲寧、溝口出、古澤純一、千葉祐規乃、伊藤正裕、善本隆之
- Journal Title
  
  炎症と免疫
  
  Volume: Vol.23, No.2 Pages: 66-72
- Data Source
  KAKENHI-PROJECT-15K08937
[Journal Article] Immunosurveillance markers may predict patients who can discontinue imatinib therapy without relapse.2014
- Author(s)
  Yoshimoto, T., Mizoguchi, I., Katagiri, S., Tauchi, T., Furusawa, J., Chiba, Y., Mizuguchi, J., Ohyashiki, J. H., and Ohyashiki, K.
- Journal Title
  
  Oncoimmunology
  
  Volume: 3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26670588
[Journal Article] Immunosurveillance markers may predict patients who can discontinue imatinib therapy without relapse.2014
- Author(s)
  Yoshimoto, T., Mizoguchi, I., Katagiri, S., Tauchi, T., Furusawa, J., Chiba, Y., Mizuguchi, J., Ohyashiki, J. H., and Ohyashiki, K.
- Journal Title
  
  Oncoimmunology
  
  Volume: 3
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24370058
[Journal Article] Intratumoral CD4+ T Lymphodepletion Sensitizes Poorly Immunogenic Melanomas to Immunotherapy with an OX40 Agonist.2014
- Author(s)
  Fujiwara, S., Nagai, H., Shimoura, N., Oniki, S., Yoshimoto, T., and Nishigori, C.
- Journal Title
  
  Journal of Investigative Dermatology
  
  Volume: 134 Pages: 1884-1892
- DOI
  10.1038/jid.2014.42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24370058, KAKENHI-PROJECT-24659595, KAKENHI-PUBLICLY-25118727, KAKENHI-PROJECT-25461692
[Journal Article] The ARNT-Stat3 axis regulates the differentiation of intestinal intraepithelial TCRαβ^+CD8αα^+ cells2014
- Author(s)
  Nakajima K, Maekawa K, Kataoka K, Ishifune C, Nishida J, Arimochi H, Yoshimoto T, Tomita S, Nagahiro S, Yasutomo K.
- Journal Title
  
  Nat Communications
  
  Volume: 4 Pages: 1-11
- DOI
  10.1038/ncomms3112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500958, KAKENHI-PROJECT-23590475, KAKENHI-PROJECT-24370058, KAKENHI-PROJECT-24590381, KAKENHI-PROJECT-24590585, KAKENHI-PROJECT-24659595, KAKENHI-PUBLICLY-25118727
[Journal Article] Immunological control of chronic myeloid leukemia leading to treatment-free remission.2014
- Author(s)
  Mizoguchi, I., Yoshimoto, T., Katagiri, S., Furusawa, J., Chiba, Y., Mizuguchi, J., Tauchi, T., Ohyashiki, J. H., and Ohyashiki, K.
- Journal Title
  
  J. Hematol. Transfus.
  
  Volume: 2(3) Pages: 1024-1024
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24370058
[Journal Article] Immunosurveillance markers may predict patients who can discontinue imatinib therapy without relapse.2014
- Author(s)
  Yoshimoto, T., Mizoguchi, I., Katagiri, S., Tauchi, T., Furusawa, J., Chiba, Y., Mizuguchi, J., Ohyashiki, J. H., and Ohyashiki, K.
- Journal Title
  
  Oncoimmunology
  
  Volume: 3
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-25118727
[Journal Article] Downregulated microRNA-148b in circulating PBMCs in chronic myeloid leukemia patients with undetectable minimal residual disease: a possible biomarker to discontinue imatinib safely.2014
- Author(s)
  Ohyashiki, J. H., Ohtsuki, K., Mizoguchi, I., Yoshimoto, T., Katagiri, S., Umezu, T., and Ohyashiki, K.
- Journal Title
  
  Drug Des Devel Ther.
  
  Volume: 8 Pages: 1151-1159
- DOI
  10.2147/dddt.s66812
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24370058, KAKENHI-PROJECT-24790091, KAKENHI-PUBLICLY-25118727, KAKENHI-PROJECT-25830089
[Journal Article] Immunological control of chronic myeloid leukemia leading to treatment-free remission.2014
- Author(s)
  Mizoguchi, I., Yoshimoto, T., Katagiri, S., Furusawa, J., Chiba, Y., Mizuguchi, J., Tauchi, T., Ohyashiki, J. H., and Ohyashiki, K.
- Journal Title
  
  J. Hematol. Transfus.
  
  Volume: 2(3) Pages: 1024-1024
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25118727
[Journal Article] Contribution of IL-12/IL-35 Common Subunit p35 to Maintaining the Testicular Immune Privilege2014
- Author(s)
  Terayama H, Yoshimoto T, Hirai S, Naito M, Qu N, Hatayama N, Hayashi S, Mitobe K, Furusawa J, Mizoguchi I, Kezuka T, Goto H, Suyama K, Moriyama H, Sakabe K, Itoh M.
- Journal Title
  
  PLoS One
  
  Volume: 9
- DOI
  10.1371/journal.pone.0096120
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23500504, KAKENHI-PROJECT-24370058, KAKENHI-PROJECT-24590243, KAKENHI-PROJECT-24790091, KAKENHI-PROJECT-24791234, KAKENHI-PUBLICLY-25118727
[Journal Article] Sustained up-regulation of effector natural killer cells in chronic myeloid leukemia after discontinuation of imatinib.2013
- Author(s)
  Mizoguchi, I., Yoshimoto, T., Katagiri, S., Mizuguchi, J., Tauchi, T., Kimura, Y., Inokuchi, K., Ohyashiki, J. H., and Ohyashiki, K.
- Journal Title
  
  Cancer Sci.
  
  Volume: 104 Pages: 1146-1153
- DOI
  10.1111/cas.12216
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24370058, KAKENHI-PROJECT-24790091, KAKENHI-PUBLICLY-25118727
[Journal Article] IL-27 promotes nitric oxide production induced by LPS through STAT1, NF-κB and MAPKs2013
- Author(s)
  Shimizu M, Ogura K, Mizoguchi I, Chiba Y, Higuchi K, Ohtsuka H, Mizuguchi J, Yoshimoto T
- Journal Title
  
  Immunobiology
  
  Volume: 218 Pages: 628-634
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659595
[Journal Article] Sustained up-regulation of effector natural killer cells in chronic myeloid leukemia after discontinuation of imatinib2013
- Author(s)
  Mizoguchi I, Yoshimoto T, Katagiri S, Mizuguchi J, Tauchi T, Kimura Y, Inokuchi K, Ohyashiki JH, Ohyashiki K
- Journal Title
  
  Cancer Sci
  
  Volume: 104 Pages: 1146-1153
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659595
[Journal Article] IL-27 promotes nitric oxide production induced by LPS through STAT1, NF-κB and MAPKs.2013
- Author(s)
  Shimizu, et al.
- Journal Title
  
  Immunobiology
  
  Volume: 218 Pages: 628-634
- DOI
  10.1016/j.imbio.2012.07.028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24370058, KAKENHI-PROJECT-24659595, KAKENHI-PROJECT-24790091, KAKENHI-PUBLICLY-25118727
[Journal Article] IL-27 promotes nitric oxide production induced by LPS through STAT1, NF-KB and MAPKs2013
- Author(s)
  Shimizu M, Ogura K, Mizoguchi I, Chiba Y, Higuchi K, Ohtsuka H, Mizuguchi J, Yoshimoto T
- Journal Title
  
  Immunobiology
  
  Volume: 218 Pages: 628-634
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590475
[Journal Article] Pivotal roles of T-helper 17-related cytokines, IL-17, IL-22 and IL-23, in inflammatory diseases2013
- Author(s)
  Qu N, Xu M, Mizoguchi I, Furusawa J, Kaneko K, Watanabe K, Mizuguchi J, Itoh M,Kawakami Y, Yoshimoto T.
- Journal Title
  
  Clin Dev Immunol
  
  Volume: 2013:968549 Pages: 1-13
- DOI
  10.1155/2013/968549
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240128, KAKENHI-PROJECT-23590475, KAKENHI-PROJECT-24370058, KAKENHI-PROJECT-24590243, KAKENHI-PROJECT-24659595, KAKENHI-PROJECT-24790091, KAKENHI-PUBLICLY-25118727, KAKENHI-PROJECT-25670506
[Journal Article] IL-27 enhances the expression of TRAIL and TLR3 in human melanomas and inhibits their tumor growth in cooperating with a TLR3 agonist poly(I : C) partly in TRAIL-dependent manner2013
- Author(s)
  Chiba Y, Mizoguchi K, Mitobe I, Higuchi K, Nagai H, Nishigori C, Mizuguchi J, Yoshimoto T
- Journal Title
  
  PLoS One
  
  Volume: 8(10)
- DOI
  10.1371/journal.pone.0076159
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590475, KAKENHI-PROJECT-24370058, KAKENHI-PROJECT-24659595, KAKENHI-PROJECT-24790091, KAKENHI-PUBLICLY-25118727
[Journal Article] IL-17 versus IL-27 : Opposite effects on TNF-α-induced chemokine production in human keratinocytes2012
- Author(s)
  Fujiwara S, Nagai H, Oniki S, Yoshimoto T, Nishigori C
- Journal Title
  
  Experimental Dermatology
  
  Volume: 21 Pages: 70-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591220
[Journal Article] サイトカインのすべてIL-352012
- Author(s)
  徐明利、千葉祐規乃、善本隆之
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 57(Suppl.21) Pages: 220-230
- Data Source
  KAKENHI-PROJECT-23590475
[Journal Article] サイトカインのすべてIL-272012
- Author(s)
  千葉祐規乃、溝口出、森嶋紀子、徐明利、善本隆之
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 57 (Suppl. 21) Pages: 172-183
- Data Source
  KAKENHI-PROJECT-24659595
[Journal Article] DCワクチンをリンパ節投与した際の局所滞留性と免疫誘導能の検討2012
- Author(s)
  太田裕士、徐明利、溝口出、高梨正勝、須藤カツ子、黒田雅彦、善本隆之、粕谷和彦、土田明彦、畝崎榮
- Journal Title
  
  東京医科大学雑誌
  
  Volume: 70(4) Pages: 444-449
- NAID
  10031143025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590475
[Journal Article] DCワクチンをリンパ節投与した際の局所滞留性と免疫誘導能の検討2012
- Author(s)
  太田裕士、徐明利、溝口出、高梨正勝、須藤カツ子、黒田雅彦、善本隆之、粕谷和彦、土田明彦、畝崎栄
- Journal Title
  
  東京医科大学雑誌
  
  Volume: 70(4) Pages: 444-449
- NAID
  10031143025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659595
[Journal Article] Interleukin (IL)-17 versus IL-27 : opposite effects on TNF-α-induced chemokine production in human keratinocytes2012
- Author(s)
  S. Fujiwara, H. Nagai, S. Oniki, T. Yoshimoto, and C. Nishigori
- Journal Title
  
  Exp. Dermatol.
  
  Volume: 21 Pages: 70-72
- DOI
  10.1111/j.1600-0625.2011.01384.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591220, KAKENHI-PROJECT-24370058
[Journal Article] サイトカインのすべてIL-272012
- Author(s)
  千葉祐規乃、溝口出、森嶋紀子、徐明利、善本隆之
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 57(Suppl.21) Pages: 172-183
- Data Source
  KAKENHI-PROJECT-23590475
[Journal Article] Epithelial cell-derived IL-25, but not Th17 cell-derived IL-17 or IL-17F, is crucial for murine asthma2012
- Author(s)
  Suzukawa M, Morita H, Nambu A, Arae K, Shimura E, Shibui A, Yamaguchi S, Suzukawa K, Nakanishi W, Oboki K, Kajiwara N, Ohno T, Ishii A, Korner H, Cua DJ, Suto H, Yoshimoto T, Iwakura Y, Yamasoba T, Ohta K, Sudo K, Saito H, Okumura K, Broide DH, Matsumoto K, Nakae S
- Journal Title
  
  J Immunol
  
  Volume: 189(7) Pages: 3641-3652
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659595
[Journal Article] Epithelial cell-derived IL-25, but not Th17 cell-derived IL-17 or IL-17F, is crucial for murine asthma2012
- Author(s)
  Suzukawa M, Morita H, Nambu A, Arae K, Shimura E, Shibui A, Yamaguchi S, Suzukawa K, Nakanishi W, Oboki K, Kajiwara N, Ohno T, Ishii A, Korner H, Cua DJ, Suto H, Yoshimoto T, Iwakura Y, Yamasoba T, Ohta K, Sudo K, Saito H, Okumura K, Broide DH, Matsumoto K, Nakae S
- Journal Title
  
  J Immunol
  
  Volume: 189(7) Pages: 3641-3652
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590475
[Journal Article] Interleukin (IL)-17 versus IL-27: opposite effects on TNF- -induced chemokine production in human keratinocytes2012
- Author(s)
  Fujiwara, S., Nagai, H., Oniki, S., Yoshimoto, T. and Nishigori, C.
- Journal Title
  
  Exp. Dermatol
  
  Volume: 21 Pages: 70-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590475
[Journal Article] Identification of a novel role of septin 10 in paclitaxel-resistance in cancers through a functional genomics screen2012
- Author(s)
  Xu M, Takanashi M, Oikawa K, Nishi H, Isaka K, Yoshimoto T, Ohyashiki J, Kuroda M
- Journal Title
  
  Cancer Sci
  
  Volume: 103(4) Pages: 821-827
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590475
[Journal Article] Identification of a novel role of septin 10 in paclitaxel-resistance in cancers through a functional genomics screen2012
- Author(s)
  Xu M, Takanashi M, Oikawa K, Nishi H, Isaka K, Yoshimoto T, Ohyashiki J, Kuroda M
- Journal Title
  
  Cancer Sci
  
  Volume: 103(4) Pages: 821-827
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659595
[Journal Article] IL-23 gene therapy for mouse bladder tumor cell lines2011
- Author(s)
  T. Kuramoto, R Fujii, H. Nagai, M.L.Belladonna, T. Yoshimoto, Y. Kohjimoto, T. Inagaki, and I. Hara.
- Journal Title
  
  BJU int
  
  Volume: 108 Pages: 914-921
- DOI
  10.1111/j.1464-410x.2010.10025.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591220
[Journal Article] IL-27 suppresses RANKL expression in CD4+ T cells in part through STAT32011
- Author(s)
  Kamiya S, Okumura M, Chiba Y, Nakamura C, Fukawa T, Nimura N, Mizuguchi J, Wada S, Yoshimoto T
- Journal Title
  
  Immunol. Let
  
  Volume: 138 Pages: 47-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590475
[Journal Article] Regulation of the development of acute hepatitis by IL-23 through IL-22 and IL-17 production2011
- Author(s)
  Xu M, Morishima N, Mizoguchi I, Chiba Y, Fujita K, Kuroda M, Iwakura Y, Cua DJ, Yasutomo K, Mizuguchi J, Yoshimoto T
- Journal Title
  
  Eur J. Immunol
  
  Volume: 41 (10) Pages: 2828-2839
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590475
[Journal Article] IL-23 gene therapy for mouse bladder tumor cell lines2011
- Author(s)
  Kuramoto T, Fujii R, Nagai H, Belladonna ML, Yoshimoto T, Kohjimoto Y, Inagaki T, Hara I
- Journal Title
  
  BJU Int
  
  Volume: 108 Pages: 914-921
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590475
[Journal Article] IL-12、モデル動物利用マニュアル2011
- Author(s)
  奥村昌恵、徐明利、善本隆之
- Journal Title
  
  LIC
  
  Pages: 266-275
- Data Source
  KAKENHI-PROJECT-23590475
[Journal Article] Local expression of IL-27 ameliorates collagen induced arthritis2011
- Author(s)
  Pickens SR, Volin MV, Mandelin II, AM, Matsui M, Yoshimoto T, Shahrara S
- Journal Title
  
  Arthritis Rheum
  
  Volume: 63 Pages: 2289-2298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590475
[Journal Article] Notch signaling drives IL-22 secretion in CD4^+ T cells by stimulating the aryl hydrocarbon receptor.2010
- Author(s)
  Alam M.S., Maekawa Y., Kitamura A., Tanigaki K., Yoshimoto T., Kishiara K., Yasutomo K.
- Journal Title
  
  Proc.Natl.Acad.Sci.U.S.A. 107
  
  Pages: 5943-5948
- Data Source
  KAKENHI-PROJECT-20370049
[Journal Article] Antitumor activities of interleukin-27 on melanoma.2010
- Author(s)
  Nagai H., Oniki S., Fujiwara S., Xu M. Mizoguchi I., Yoshimoto T., Nishigori, C.
- Journal Title
  
  Endocr.Metab.Immune Disord.Drug Targets 10
  
  Pages: 41-46
- Data Source
  KAKENHI-PROJECT-20370049
[Journal Article] Antimelanoma immunotherapy: clinical and preclinical applications of IL-12 family members2010
- Author(s)
  H. Nagai, S. Oniki, S. Fujiwara, T. Yoshimoto, and C. Nishigori
- Journal Title
  
  Immunotherapy.
  
  Volume: 2 Pages: 697-709
- DOI
  10.2217/imt.10.46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591220
[Journal Article] Anti-melanoma immunotherapy : Clinical and preclinical applications of IL-12 family members.2010
- Author(s)
  Nagai H., Oniki S., Fujiwara S., Yoshimoto T., Nishigori C.
- Journal Title
  
  Immunotherapy 5
  
  Pages: 697-709
- Data Source
  KAKENHI-PROJECT-20370049
[Journal Article] Natural occurring IL-17 producing T cells regulate the initial phase of neutrophil mediated airway responses.2009
- Author(s)
  Tanaka S., Yoshimoto T., Naka T., Nishida K., Murakami M., Hirano T., Nakae S., Iwakura Y, Cua D., Kubo M.
- Journal Title
  
  J.Immunol. 183
  
  Pages: 7523-7530
- Data Source
  KAKENHI-PROJECT-20370049
[Journal Article] TGF-b is necessary for induction of IL-23R and Th17 differentiation by IL-6 and IL-23.2009
- Author(s)
  Morishima N., Mizoguchi I., Takeda K., Mizuguchi J., Yoshimoto T.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 286
  
  Pages: 105-110
- Data Source
  KAKENHI-PROJECT-20370049
[Journal Article] Interleukins and cancer immunotherapy.2009
- Author(s)
  Yoshimoto T., Morishima N., Okumura M., Chiba Y., Xu M., Mizuguchi J.
- Journal Title
  
  Immunotherapy 1
  
  Pages: 825-844
- Data Source
  KAKENHI-PROJECT-20370049
[Journal Article] IL-27 activates natural killer (NK) cells and suppresses NK-resistant head and neck squamous cell carcinoma through inducing antibody-dependent cellular cytotoxicity.2009
- Author(s)
  Matsui M., Kishida T., Nakano H., Yoshimoto K., Shin-Ya M., Shimada T., Nakai S., Imanishi J., Yoshimoto T., Hisa Y., Mazda O.
- Journal Title
  
  Cancer Res. 69
  
  Pages: 2523-2530
- Data Source
  KAKENHI-PROJECT-20370049
[Journal Article] Expression of Interlukins-23 and 27 leads to successful gene therapy of hepatocellular carcinoma.2009
- Author(s)
  Hu P., Hu H.D., Chen M., Peng M.L., Tang L., Tang K.F., Matsui M., Belladonna M.L., Yoshimoto T., Zhang D.Z., Xiang R., Ren H.
- Journal Title
  
  Mol.Immunol. 46
  
  Pages: 1654-1662
- Data Source
  KAKENHI-PROJECT-20370049
[Journal Article] IL-18, IL-33と好塩基球2009
- Author(s)
  善本知広
- Journal Title
  
  アレルギー・免疫 16
  
  Pages: 34-42
- Data Source
  KAKENHI-PROJECT-19390121
[Journal Article] 感染症-ウイルス・細菌・寄生虫の感染戦略 : 寄生虫感染時のサイトカイン動態2009
- Author(s)
  安田好文、善本知広、中西憲司
- Journal Title
  
  実験医学 27
  
  Pages: 1665-1671
- Data Source
  KAKENHI-PROJECT-19390121
[Journal Article] 腸管寄生虫感染と宿主応答-IL-18 の線虫感染防御作用2009
- Author(s)
  善本知広、中西憲司
- Journal Title
  
  蛋白核酸酵素 54
  
  Pages: 1066-1072
- Data Source
  KAKENHI-PROJECT-19390121
[Journal Article] IFN-g is a therapeutic target molecule for prevention of postoperative adhesion formation.2008
- Author(s)
  Kosaka H., Yoshimoto T., Yoshimoto T., Fujimoto J., Nakanishi K.
- Journal Title
  
  Nat.Med. 14
  
  Pages: 437-441
- Data Source
  KAKENHI-PROJECT-20370049
[Journal Article] Association of serum IL-33 level and the IL-33 genetic variant with Japanese cedar pollinosis.2008
- Author(s)
  Sakishita M, Yoshimoto T, Hirota T, et al.
- Journal Title
  
  Clin. Exp. Allergy 38
  
  Pages: 1875-1881
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390121
[Journal Article] Administration of IL-33 induces airway hyperresponsiveness and goblet cell hyperplasia in the lungs in the absence of adaptive immune system.2008
- Author(s)
  Kondo Y, Yoshimoto T, Yasuda K, Futatsugi-Yumikura S, et al.
- Journal Title
  
  Int. Immunol. 20
  
  Pages: 791-800
- NAID
  10021241671
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390121
[Journal Article] Association of IL-33 level and IL-33 genetic variant with Japanese cedar pollinosis.2008
- Author(s)
  Sakishita M, Yoshimoto T, Hirota T, Harada M, Ohkubo K, Osawa Y, Fujieda S, Nakamura Y, Yasuda K, Nakanishi K, and Tamari M.
- Journal Title
  
  Clinical & Exp Allergy 38
  
  Pages: 1875-1881
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390121
[Journal Article] Anti-proliferative activity of IL-27 on melanoma.2008
- Author(s)
  T. Yoshimoto, N. Morishima, I. Mizoguchi, M. Shimizu, H. Nagai, S. Oniki, M. Oka, C. Nishigori, J. Mizuguchi
- Journal Title
  
  J. Immunol. 180
  
  Pages: 6527-6535
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590418
[Journal Article] アレルギーの発症とIL-172008
- Author(s)
  善本知広
- Journal Title
  
  臨床免疫・アレルギー科 50
  
  Pages: 196-203
- NAID
  40016222334
- Data Source
  KAKENHI-PROJECT-19390121
[Journal Article] Interleukin-27 directly induces differentiation in hematopoietic stem cells.2008
- Author(s)
  Seita J., Asakawa M., Ooehara J., Takayanagi S., Morita Y, Watanabe N., Fujita K., Kudo M., Mizuguchi J., Ema H., Nakauchi H., Yoshimoto T.
- Journal Title
  
  Blood 111
  
  Pages: 1903-1912
- Data Source
  KAKENHI-PROJECT-20370049
[Journal Article] Administration of IL-33 induces airway hyperresponsiveness and goblet cell hyperplasia in the lungs in the absence of adaptive immune system.2008
- Author(s)
  Kondo Y^*, Yoshimoto T^*, Yasuda K, Futatsugi-Yumikura S, Morimoto M, Hayashi N. Hoshino T, Fujimoto J, and Nakanishi K.
- Journal Title
  
  Int. Immunol. 20
  
  Pages: 791-800
- NAID
  10021241671
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390121
[Journal Article] Anti-proliferative activity of IL-27 on melanoma.2008
- Author(s)
  T. Yoshimoto
- Journal Title
  
  J. Immunol. 180
  
  Pages: 6527-6535
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370049
[Journal Article] Interferon-γ is a therapeutic target molecule for prevention of postoperative adhesion formation.2008
- Author(s)
  Kosaka H, Yoshimoto T, Fujimoto J., Nakanishi K.
- Journal Title
  
  Nat. Med. 14
  
  Pages: 437-441
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390121
[Journal Article] IL-33とアレルギー2008
- Author(s)
  松葉沙織、近藤祐一、善本知広、中西憲司
- Journal Title
  
  臨床免疫・アレルギー科 50
  
  Pages: 323-332
- NAID
  40016259729
- Data Source
  KAKENHI-PROJECT-19390121
[Journal Article] Interferon-γ is a therapeutic target molecule for prevention of postoperative adhesion formation.2008
- Author(s)
  Kosaka H^*, Yoshimoto, T^*, Yoshimoto T, Fujimoto J, and Nakanishi, K.
- Journal Title
  
  Nature Med. 14
  
  Pages: 437-441
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390121
[Journal Article] アレルギーの発症とIL-172008
- Author(s)
  善本知広.
- Journal Title
  
  臨床免疫・アレルギー科 50
  
  Pages: 196-203
- NAID
  40016222334
- Data Source
  KAKENHI-PROJECT-19390121
[Journal Article] IL-33とアレルギー2008
- Author(s)
  松葉沙織, 近藤祐一, 善本知広, 中西憲司
- Journal Title
  
  臨床免疫・アレルギー科 50
  
  Pages: 323-332
- NAID
  40016259729
- Data Source
  KAKENHI-PROJECT-19390121
[Journal Article] Anti-proliferative activity of IL-27 on melanoma2008
- Author(s)
  T. Yoshimoto, N. Morishima, I. Mizoguchi, M. Shimizu, H. Nagai, S. Oniki, M. Oka, C. Nishigori, J. Mizuguchi,
- Journal Title
  
  J.Immunol. 180
  
  Pages: 6527-6535
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590418
[Journal Article] STAT3 is indispensable to IL-27-mediated cell proliferation but not to IL-27-induced Th1 differentiation and suppression of proinflammatory cytokine production.2008
- Author(s)
  Owaki T., Asakawa M., Morishima N., Mizoguchi J. Takeda K., Fukai F., Mizuguchi J., Yoshimoto T.
- Journal Title
  
  J.Immunol. 180
  
  Pages: 2903-2911
- Data Source
  KAKENHI-PROJECT-20370049
[Journal Article] Interleukin-27 : biological properties and application to immunotherapy of cancer.2008
- Author(s)
  Yoshimoto T., Morishima N., Okumura M., Chiba Y, Onishi K., Mizoguchi I., Mizuguchi J.
- Journal Title
  
  Trend.Cancer Res. 4
  
  Pages: 93-103
- Data Source
  KAKENHI-PROJECT-20370049
[Journal Article] Anti-proliferative activity of IL-27 on melanoma.2008
- Author(s)
  Yoshimoto T., Morishima N., Mizoguchi I., Oniki S., Nagai H., Oka M., Nishigori C., Mizuguchi J.
- Journal Title
  
  J.Immunol. 180
  
  Pages: 6527-6535
- Data Source
  KAKENHI-PROJECT-20370049
[Journal Article] IL-18によるTh1型喘息の発症機序2007
- Author(s)
  善本知広
- Journal Title
  
  The 14th Symposium of Asthma in Tokyo
  
  Pages: 26-32
- Data Source
  KAKENHI-PROJECT-19390121
[Journal Article] IL-27の血管新生抑制作用2007
- Author(s)
  清水本武, 島村眞理子, 善本隆之
- Journal Title
  
  臨床免疫 47
  
  Pages: 298-302
- Data Source
  KAKENHI-PROJECT-19590418
[Journal Article] IL-18によるTh1型喘息の発症機序2007
- Author(s)
  善本知広
- Journal Title
  
  The 14th Symposium of Asthma in Tokyo 14
  
  Pages: 26-32
- Data Source
  KAKENHI-PROJECT-19390121
[Journal Article] IL-18による免疫制御-IL-18とSuper Th1細胞2007
- Author(s)
  善本知広
- Journal Title
  
  医学のあゆみ 220
  
  Pages: 198-199
- Data Source
  KAKENHI-PROJECT-19390121
[Journal Article] 蠕虫感染防御とマスト細胞2007
- Author(s)
  善本知広
- Journal Title
  
  臨床免疫・アレルギー科 47
  
  Pages: 217-225
- NAID
  40015368540
- Data Source
  KAKENHI-PROJECT-19390121
[Journal Article] IL-27 suppresses Th2 cell development and Th2 cytokines production from polarized Th2 cells; a novel therapeutic way for Th2-mediated anergic inflammation2007
- Author(s)
  T. Yoshimoto, et. al.
- Journal Title
  
  J.Immunol 179
  
  Pages: 4415-4423
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659286
[Journal Article] T helper 1 cells stimulated with ovalbumin and IL-18 induce airway hyperresponsiveness and lung fibrosis by IFN-γ and IL-13 production.2007
- Author(s)
  Hayashi N, Yoshimoto T, Izuhara K, Matsui K, Tanaka T. and Nakanishi K.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA. 104
  
  Pages: 14765-14770
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390121
[Journal Article] IL-18と気管支喘息2007
- Author(s)
  善本知広、中西憲司
- Journal Title
  
  喘息 220
  
  Pages: 198-199
- Data Source
  KAKENHI-PROJECT-19390121
[Journal Article] Th1細胞とアレルギー性炎症-IL-18とSuper Th1細胞.2007
- Author(s)
  善本知広
- Journal Title
  
  医学のあゆみ 220
  
  Pages: 944-948
- Data Source
  KAKENHI-PROJECT-19390121
[Journal Article] IL-18と気管支喘息2007
- Author(s)
  善本知広, 中西憲司
- Journal Title
  
  喘息 20
  
  Pages: 44-50
- Data Source
  KAKENHI-PROJECT-19390121
[Journal Article] IL-27の血管新生抑制作用2007
- Author(s)
  清水本武, 島村眞里子, 善本隆之
- Journal Title
  
  臨床免疫 47
  
  Pages: 298-302
- Data Source
  KAKENHI-PROJECT-19590418
[Journal Article] IL-27 suppresses Th2 cell development and Th2 cytokines production from polarized Th2 cells: a novel therapeutic way for Th2-mediated allergic inflammation.2007
- Author(s)
  Yoshimoto T, Yoshimoto T, Yasuda K, Mizuguchi J. and Nakanishi K.
- Journal Title
  
  J. Immunol. 179
  
  Pages: 4415-4423
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390121
[Journal Article] Suppresses Th2 cell development and Th2 cytokines production from polarized Th2 Cells:a novel therapeutic way for Th2-mediated allergic inflammation2007
- Author(s)
  Yoshimoto T, Yoshimoto T, Yasuda K, Mizuguchi J, Nakanishi, K
- Journal Title
  
  J.Immunol 179
  
  Pages: 4415-4423
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390121
[Journal Article] 蠕虫感染防御とマスト細胞2007
- Author(s)
  善本知広
- Journal Title
  
  臨床免疫・アレルギー科 47
  
  Pages: 217-225
- NAID
  40015368540
- Data Source
  KAKENHI-PROJECT-19390121
[Journal Article] T helper 1 cells stimulated with ovalbumin and IL-18 induce airway hyperresponsiveness and lung fibrosis by IFN-γ and IL-13 production2007
- Author(s)
  Hayashi N, Yoshimoto T, Izuhara K, Matsui K, Tanaka T, Nakanishi K.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 104
  
  Pages: 14765-14770
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390121
[Journal Article] Th1細胞とアレルギー性炎症-IL-18とSuper Th1細胞2007
- Author(s)
  善本知広
- Journal Title
  
  医学のあゆみ 220
  
  Pages: 944-948
- Data Source
  KAKENHI-PROJECT-19390121
[Journal Article] IL-18による免疫制御-IL-18とSuper Th1細胞2007
- Author(s)
  善本知広
- Journal Title
  
  医学のあゆみ 220
  
  Pages: 198-199
- Data Source
  KAKENHI-PROJECT-19390121
[Journal Article] 正電荷ポリマーによる乳癌細胞に対する遺伝子導入の基礎研究. 査読有2007
- Author(s)
  武田泰隆、榮光子、善本隆之、森本純司、清水本武、柳衛広宣
- Journal Title
  
  乳癌基礎研究 16
  
  Pages: 43-49
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590418
[Journal Article] 正電荷ポリマーによる乳癌細胞に対する遺伝子導入の基礎研究2007
- Author(s)
  武田泰隆, 栄光子, 善本隆之, 森本純司, 清水本武, 柳衛広宣
- Journal Title
  
  乳癌基礎研究 16
  
  Pages: 43-49
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590418
[Journal Article] Synergistic antitumor effect by coexpression of chemokine CCL21/SLC and costimulatory molecule LIGHT.2004
- Author(s)
  Hisada M, Yoshimoto T, Kamiya S, Magami Y, Miyaji H, Yoneto T, Tamada K, Aoki T, Koyanagi Y, Mizuguchi J.
- Journal Title
  
  Cancer Gene Ther. 11
  
  Pages: 280-288
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15592003
[Journal Article] Potent antitumor activity of interleukin-27.2004
- Author(s)
  Hisada M, Kamiyama S, Fujita K, Belladonna ML, Aoki T, Koyanagi Y, Mizuguchi J, Yoshimoto T.
- Journal Title
  
  Cancer Res. 64
  
  Pages: 1152-1156
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15592003
[Journal Article] Retrovirus-mediated transduction of TRAIL and chemotherapeutic agents co-operatovely induce apoptosis cell death in both sarcoma and myeloma cells.2003
- Author(s)
  Suzuki H, Hotta T, Koyama T, Komagata M, Imakiire A, Yanase N, Yoshimoto T, Mizuguchi J.
- Journal Title
  
  Anticancer Res. 23
  
  Pages: 3247-3253
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15592003
[Journal Article] Local expression of IL-27 ameliorates collagen induced arthritis.
- Author(s)
  Pickens S.R., Volin M.V., Mandelin II A.M., Matsui M., Yoshimoto T., Shahrara S.
- Journal Title
  
  Arthritis Rheum. (in press)
- Data Source
  KAKENHI-PROJECT-20370049
[Journal Article] IL-23 gene therapy for mouse bladder tumor cell lines.
- Author(s)
  Kuramoto T., Fujii R., Nagai H., Belladonna M.L., Yoshimoto T., Kohjimoto Y., Inagaki T., Hara I.
- Journal Title
  
  BJU Int. (in press)
- Data Source
  KAKENHI-PROJECT-20370049
[Journal Article] A pivotal role for interleukin-27 in CD8^+ T cell functions and generation of cytotoxic T lymphocytes.
- Author(s)
  Morishima N., Mizoguchi I., Okumura M., Chiba Y., Xu M., Shimizu M., Matsui M., Mizuguchi J., Yoshimoto T.
- Journal Title
  
  J.Biomed.Biotech. (in press)
- Data Source
  KAKENHI-PROJECT-20370049
[Journal Article] IL-27 suppresses RANKL expression in CD4^+ T cells in part through STAT3.
- Author(s)
  Kamiya S., Okumura M., Chiba Y., Nakamura C., Fukawa T., Nimura N., Mizuguchi J., Wada S., Yoshimoto, T.
- Journal Title
  
  Immuuol.Let. (in press)
- Data Source
  KAKENHI-PROJECT-20370049
[Journal Article] Regulation of antitumor immune responses by the IL-12 family cytokines, IL-12, IL-23 and IL-27.
- Author(s)
  Xu M., Mizoguchi I., Morishima N., Chiba Y., Mizuguchi J., Yoshimoto T.
- Journal Title
  
  Clin.Dev.Immunol. (in press)
- Data Source
  KAKENHI-PROJECT-20370049
[Journal Article] Contribution of basophils to Th2/IgE response in vivo by production of IL-4 and presentation of MHC class II/peptide complex to CD4^+ T cells.
- Author(s)
  Yoshimoto T, Yasuda K, Tanaka H, Nakahira M, Imai Y, Fujimori Y, and Nakanishi K.
- Journal Title
  
  Nature Immunol. in press
  
  Pages: 0-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390121
[Patent] 実験動物の腸管癒着を形成する方法、腸管癒着実験動物の製造方法、腸管癒着抑制剤のスクリーニング方法及び腸管癒着抑制剤2008
- Inventor(s)
  善本知広、中西憲司、藤元治朗
- Industrial Property Rights Holder
  善本知広、中西憲司、藤元治朗
- Filing Date
  2008-02-14
- Data Source
  KAKENHI-PROJECT-19390121
[Patent] Th2細胞誘導用組成物およびTh2型疾患の治療組成物, ならびにこれらの利用2008
- Inventor(s)
  善本知広, 中西憲司
- Industrial Property Rights Holder
  善本知広, 中西憲司
- Industrial Property Number
  2008-281930
- Filing Date
  2008-10-30
- Data Source
  KAKENHI-PROJECT-19390121
[Patent] Th2細胞誘導用組成物およびTh2型疾患の治療組成物, ならびにこれらの利用2008
- Inventor(s)
  善本知広、中西憲司
- Industrial Property Rights Holder
  善本知広、中西憲司
- Industrial Property Number
  2008-281930
- Filing Date
  2008-10-31
- Data Source
  KAKENHI-PROJECT-19390121
[Patent] 実験動物の腸管癒着を形成する方法、腸管癒着実験動物の製造方法、腸管癒着抑制剤のスクリーニング方法及び腸管癒着抑制剤2008
- Inventor(s)
  善本知広、藤元治朗、中西憲司
- Industrial Property Rights Holder
  JST
- Filing Date
  2008-02-13
- Overseas
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] Comparative analysis of the major parameters of bone marrow derived mesenchymal stem cells, obtained from young and elderly donors.2019
- Author(s)
  Yoshimoto T.
- Organizer
  International Toxicological school by Ukrainian Toxicology Society
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09105
[Presentation] Development of a novel alternative method for evaluation of sensitizing potential and allergenicity by measuring human T cell activation and differentiation in vitro.2019
- Author(s)
  Mizoguchi I, Inoue S, Orii N, Hasegawa H, Xu X, Yoshimoto T.
- Organizer
  第48回日本免疫学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-18K11658
[Presentation] EBI3, one of subunits shared among the IL-12 cytokine family, plays a critical role in up-regulation of MHC class I during DC maturation.2019
- Author(s)
  Mizoguchi I, Hasegawa H, Orii N, Inoue S, Kawana C, Yoneto T, Xu M, Yoshimoto T.
- Organizer
  17th International Congress of Immunology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09105
[Presentation] 滑脳症に伴うてんかん性脳症双胎例に対するフローサイトメトリーを用いた免疫学的アプローチ2019
- Author(s)
  山中　岳、溝口　出、山崎崇志、高松朋子、小穴信吾、石田　悠、森地振一郎、柏木保代、善本隆之、河島尚志
- Organizer
  第31回日本神経免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-16K10000
[Presentation] 炎症誘導時の新しい蛋白質発現増強機構2019
- Author(s)
  善本隆之
- Organizer
  平成26年度選定戦略的研究基盤形成支援事業進捗状況報告会
- Data Source
  KAKENHI-PROJECT-19K06570
[Presentation] EBI3, one of subunits shared among the IL-12 cytokine family, plays a critical role in up-regulation of MHC class I during DC maturation.2019
- Author(s)
  Mizoguchi I, Hasegawa H, Orii N, Inoue S, Kawana C, Yoneto T, Xu M, Yoshimoto T.
- Organizer
  17th International Congress of Immunology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06570
[Presentation] 化学物質のアレルギー感作性・誘発性を評価する新規動物実験代替法の開発2019
- Author(s)
  溝口　出、川名千晶、井上槙也、折井直子、長谷川英哲、米戸敏彦、徐　明利、善本隆之
- Organizer
  第32回日本動物実験代替法学会
- Data Source
  KAKENHI-PROJECT-18K11658
[Presentation] Comparative analysis of the major parameters of bone marrow derived mesenchymal stem cells, obtained from young and elderly donors.2019
- Author(s)
  Yoshimoto T.
- Organizer
  International Toxicological school by Ukrainian Toxicology Society
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07333
[Presentation] Comparative analysis of the major parameters of bone marrow derived mesenchymal stem cells, obtained from young and elderly donors.2019
- Author(s)
  Yoshimoto T.
- Organizer
  International Toxicological school by Ukrainian Toxicology Society
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06570
[Presentation] Antitumor effects of IL-27 against a mouse chronic myeloid leukemia (CML) model.2019
- Author(s)
  Orii N, Hasegawa H, Xu M, Mizoguchi I, Yoshida H, Yoshimoto T.
- Organizer
  第183回東京医科大学医学会総会
- Data Source
  KAKENHI-PROJECT-18K07333
[Presentation] フローサイトメトリーを用いた小児けいれん性疾患に対するMonocyteの細胞内サイトカインの検討2019
- Author(s)
  山中岳、溝口　出、山崎崇志、高松朋子、春日晃子、加納佳奈子、石井知愛子、小穴信吾、石田　悠、竹下美佳、森下那月美、森地振一郎、呉　宗憲、柏木保代、善本隆之、河島尚志
- Organizer
  第13回日本てんかん学会関東甲信越地方会
- Data Source
  KAKENHI-PROJECT-16K10000
[Presentation] A new heterodimeric cytokine consisting of IL-23p19 plays a role in promotion of differentiation into GM-CSF-producing CD4+ T cells.2019
- Author(s)
  Hasegawa H, Orii N, Inoue S, Kawana C, Yoneto T, Xu M, Mizoguchi I, Yoshimoto T.
- Organizer
  17th International Congress of Immunology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09105
[Presentation] EBI3, one of subunits shared among the IL-12 cytokine family, plays a critical role in up-regulation of MHC class I during DC maturation.2019
- Author(s)
  Mizoguchi I, Hasegawa H, Orii N, Inoue S, Kawana C, Yoneto T, Xu M, Yoshimoto T.
- Organizer
  17th International Congress of Immunology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07333
[Presentation] IL-12ファミリーサイトカインの共通サブユニットEBI3による樹状細胞の成熟化におけるMHCクラスＩ発現の増強2019
- Author(s)
  井上槙也、溝口　出、長谷川英哲、折井直子、川名千晶、米戸敏彦、徐　明利、善本隆之
- Organizer
  第84回日本インターフェロン・サイトカイン学会学術集会
- Data Source
  KAKENHI-PROJECT-19K06570
[Presentation] Development of a novel alternative method for evaluation of sensitizing potential and allergenicity by measuring human T cell activation and differentiation in vitro.2019
- Author(s)
  Mizoguchi I, Inoue S, Orii N, Hasegawa H, Xu M, Yoshimoto T.
- Organizer
  第48回日本免疫学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-18K07333
[Presentation] アレルギー感作性・誘発性を評価する新規動物実験代替法の開発2019
- Author(s)
  溝口　出、川名千晶、井上槙也、折井直子、長谷川英哲、米戸敏彦、徐　明利、善本隆之
- Organizer
  第8回医薬工3大学包括連携推進シンポジウム
- Data Source
  KAKENHI-PROJECT-18K11658
[Presentation] 慢性骨髄性白血病(CML)マウスモデルを用いたCML発症におけるIL-27の役割2019
- Author(s)
  折井直子、長谷川英哲、米戸敏彦、徐　明利、大脇敏之、溝口　出、善本隆之
- Organizer
  東京医科大学記念館ポスター発表懇談会
- Data Source
  KAKENHI-PROJECT-18K07333
[Presentation] IL-12ファミリーサイトカインの共通サブユニットEBI3による樹状細胞の成熟化におけるMHCクラスＩ発現の増強2019
- Author(s)
  井上槙也、溝口　出、長谷川英哲、折井直子、川名千晶、米戸敏彦、徐　明利、善本隆之
- Organizer
  第84回日本インターフェロン・サイトカイン学会学術集会
- Data Source
  KAKENHI-PROJECT-19K09105
[Presentation] ヒト間葉系幹細胞によるIL-27の関与2018
- Author(s)
  大脇敏之、溝口出、長谷川英哲、折井直子、善本隆之
- Organizer
  第181回東京医科大学医学会総会
- Data Source
  KAKENHI-PROJECT-17K11030
[Presentation] 新しい3次元共培養系を用いた呼吸器感作性代替法の開発2018
- Author(s)
  善本隆之、大橋美緒、長谷川英哲、折井直子、徐明利、大脇敏之、溝口　出
- Organizer
  第45回日本毒性学会学術年会
- Invited
- Data Source
  KAKENHI-PROJECT-18K11658
[Presentation] Antitumor effects of IL-27 against a mouse chronic myeloid leukemia (CML) model.2018
- Author(s)
  Orii, N., Hasegawa, H., Xu, M., Mizoguchi, I., Yoshida, H., and Yoshimoto, T.
- Organizer
  第182回東京医科大学医学会総会
- Data Source
  KAKENHI-PROJECT-18K07333
[Presentation] Antitumor effects of IL-27 against a mouse chronic myeloid leukemia model.2018
- Author(s)
  Orii, N., Hasegawa, H., Xu, M., Mizoguchi, I., Yoshida, H., and Yoshimoto, T.
- Organizer
  第47回日本免疫学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-18K07333
[Presentation] A novel role for EBI3 to augment IL-23Rα protein expression through a lectin chaperone calnexin.2018
- Author(s)
  Mizoguchi, I., Ohashi, M., Hasegawa, H., Chiba, Y., Orii, N., Kan, S., Xu, M., Ochiai, N., Owaki, T., and Yoshimoto, T.
- Organizer
  東京医科大学記念館ポスター発表懇談会
- Data Source
  KAKENHI-PROJECT-15K07947
[Presentation] 化学物質の呼吸器感作性in vitro評価法の開発2018
- Author(s)
  溝口　出、折井直子、長谷川英哲、善本隆之
- Organizer
  第6期LRI研究報告会
- Data Source
  KAKENHI-PROJECT-18K11658
[Presentation] Prediction of chemical respiratory and contact sensitizers by OX40L expression in dendritic cells using a novel 3D co-culture system.2018
- Author(s)
  Ohashi, M., Mizoguchi, I., Chiba, Y., Hasegawa, H., Orii, N., Kan, S., Xu, M., Ochiai, N., Owaki, T., and Yoshimoto, T.
- Organizer
  東京医科大学記念館ポスター発表懇談会
- Data Source
  KAKENHI-PROJECT-18K11658
[Presentation] ヒト間葉系幹細胞による免疫調節とIL-27の関係性2018
- Author(s)
  大脇敏之、菅原京加、落合央、溝口出、千葉佑規乃、長谷川英哲、折井直子、宮本泰則、弓場俊輔、善本隆之
- Organizer
  第16回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-17K11030
[Presentation] Protective role for IL-27 in the development of mouse chronic myeloid leukemia model.2018
- Author(s)
  Orii, N., Mizoguchi, I., Chiba, Y., Hasegawa, H., Xu, M., Ochiai, N., Mochizuki, Y., Owaki, T., and Yoshimoto, T.
- Organizer
  The 45th NATITO CONFERENCE ON Immunological and Molecular Bases for Cancer Immunotherapy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07333
[Presentation] Prediction of chemical respiratory sensitizers by OX40L expression in dendritic cells using a new 3D co-culture system.2018
- Author(s)
  Yoshimoto, T., Hasegawa, H., Naoko, O., Xu, M., and Mizoguchi, I.
- Organizer
  The 4th International Conference on Toxicity Testing Alternatives & Translational Toxicology and the 2nd Asian Congress on Alternatives.
- Data Source
  KAKENHI-PROJECT-18K11658
[Presentation] ヒト臍帯血由来間葉系幹細胞による免疫調節とIL-27の関係性2018
- Author(s)
  大脇敏之、溝口出、杉山大介、善本隆之
- Organizer
  第83回日本インターフェロン・サイトカイン学会学術集会
- Data Source
  KAKENHI-PROJECT-17K11030
[Presentation] 慢性骨髄性白血病(CML)マウスモデルを用いたCML発症におけるIL-27の抗腫瘍効果2018
- Author(s)
  折井直子、長谷川英哲、溝口　出、仲　一仁、善本隆之
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K07333
[Presentation] IL-27/IL-35共通サブユニットEBI3によるIL-23Rの新しい蛋白質発現安定化機構2017
- Author(s)
  溝口出、千葉祐規乃、長谷川英哲、大橋美緒、中村涼乃、折井直子、干詩宇、徐明利、大脇敏之、善本隆之
- Organizer
  第6回医薬工3大学包括連携推進シンポジウム
- Data Source
  KAKENHI-PROJECT-15K07947
[Presentation] A novel role for Epstein-Barr virus-induced gene 3 to augment IL-23 receptor α protein expression through a lectin chaperone calnexin.2017
- Author(s)
  Mizoguchi, I., Ohashi, M., Hasegawa, H., Chiba, Y., Xu, M., and Yoshimoto, T.
- Organizer
  第46回日本免疫学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-15K07947
[Presentation] A novel antitumor activity of IL-27 by promoting the differentiation of HSCs to antitumorigenic M1-like macrophages in tumor-bearing mice.2017
- Author(s)
  Chiba, Y., Ohashi, M., Hasegawa, H., Xu, M., Owaki, T., Mizoguchi, I., and Yoshimoto, T.
- Organizer
  The 2nd International Conference on Cytokine Signaling in Cancer
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08433
[Presentation] A novel role for Epstein-Barr virus-induced gene 3 to augment IL-23 receptor α protein expression through a lectin chaperone calnexin.2017
- Author(s)
  Mizoguchi, I., Ohashi, M., Hasegawa, H., Chiba, Y., Xu, M., and Yoshimoto, T.
- Organizer
  第46回日本免疫学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-15K08433
[Presentation] Prediction of chemical respiratory and contact sensitizers by OX40L expression in dendritic cells using a novel 3D co-culture system.2017
- Author(s)
  Ohashi, M., Mizoguchi, I., Chiba, Y., Hasegawa, H., Xu, M., and Yoshimoto, T.
- Organizer
  第46回日本免疫学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-15K08433
[Presentation] IL-27/IL-35共通サブユニットEBI3によるIL-23Rの新しい蛋白質発現安定化機構2017
- Author(s)
  溝口出、千葉祐規乃、長谷川英哲、大橋美緒、中村涼乃、折井直子、干詩宇、徐明利、大脇敏之、善本隆之
- Organizer
  第6回医薬工3大学包括連携推進シンポジウム
- Data Source
  KAKENHI-PROJECT-17K11030
[Presentation] 滑脳症に伴う難治性てんかん双胎例のサイトカイン産生能の検討2017
- Author(s)
  山中　岳、溝口　出、小穴信吾、石田　悠、竹下美佳、森下那月美、森地振一郎、浦辺智美、呉　宗憲、柏木保代、麻生誠二郎、加藤光広、善本隆之、河島尚志
- Organizer
  第66回小児神経関東地方会
- Place of Presentation
  日本医大橘桜会館（東京都文京区）
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-16K10000
[Presentation] フローサイトメトリーによる複雑型熱性けいれんの免疫学的検討2017
- Author(s)
  森　　朋子、山中　岳，竹下　美佳，森下那月美，森地振一郎，呉　　宗憲，石田　　悠，小穴　信吾，柏木　保代，河島　尚志，溝口　　出，善本　隆之
- Organizer
  第51回日本てんかん学会学術集会
- Data Source
  KAKENHI-PROJECT-16K10000
[Presentation] A novel antitumor activity of IL-27 by promoting the differentiation of HSCs to antitumorigenic M1-like macrophages in tumor-bearing mice.2017
- Author(s)
  Chiba, Y., Ohashi, M., Hasegawa, H., Xu, M., Owaki, T., Mizoguchi, I., and Yoshimoto, T.
- Organizer
  The 2nd International Conference on Cytokine Signaling in Cancer
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07947
[Presentation] Promotion of expansion and differentiation of hematopoietic stem cells by IL-27 into myeloid progenitors to control infection in emergency myelopoiesis.2016
- Author(s)
  Yoshimoto, T., Furusawa, J., Chiba, Y., Xu, M., Hasegawa, H., Nakae, S., Kobayashi, F., Yoshida, H., and Mizoguchi, I. Ohashi, M., Hasegawa, H., and Mizoguchi, I.
- Organizer
  Symposium, 16th International Congress of Immunology
- Place of Presentation
  Melbourne, Australia
- Year and Date
  2016-08-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08433
[Presentation] Promotion of expansion and differentiation of hematopoietic stem cells by IL-27 into myeloid progenitors to control infection in emergency myelopoiesis.2016
- Author(s)
  Yoshimoto, T., Furusawa, J., Chiba, Y., Xu, M., Hasegawa, H., Nakae, S., Kobayashi, F., Yoshida, H., and Mizoguchi, I. Ohashi, M., Hasegawa, H., and Mizoguchi, I.
- Organizer
  Symposium, 16th International Congress of Immunology
- Place of Presentation
  Melbourne, Australia
- Year and Date
  2016-08-21
- Data Source
  KAKENHI-PROJECT-15K07947
[Presentation] A pivotal role for IL-23p19 produced by activated CD4+ T cells in development of EAE.2016
- Author(s)
  Hasegawa, H., Mizoguchi, I., Chiba, Ohashi, M., C., Xu, M., and Yoshimoto, T.
- Organizer
  第45回日本免疫学会総会・学術集会
- Place of Presentation
  沖縄
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-15K07947
[Presentation] IL-27 induces antitumor activity by promoting differentiation of HSCs to M1-like antitumorigenic macrophages and their mobiliziation into tumor.2016
- Author(s)
  Chiba, Y., Mizoguchi, I., Hasegawa, H., Ohashi, M., C., Xu, M., and Yoshimoto, T.
- Organizer
  第45回日本免疫学会総会・学術集会
- Place of Presentation
  沖縄
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-15K07947
[Presentation] Development of a novel 3D co-culture system for evaluation of respiratory sensitizing potential.2016
- Author(s)
  Ohashi, M., Mizoguchi, I., Hasegawa, H., Chiba, C., Xu, M., and Yoshimoto, T.
- Organizer
  第45回日本免疫学会総会・学術集会
- Place of Presentation
  沖縄
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-15K07947
[Presentation] IL-27 induces antitumor activity by promoting differentiation of HSCs to M1-like antitumorigenic macrophages and their mobiliziation into tumor.2016
- Author(s)
  Chiba, Y., Mizoguchi, I., Hasegawa, H., Ohashi, M., C., Xu, M., and Yoshimoto, T.
- Organizer
  第45回日本免疫学会総会・学術集会
- Place of Presentation
  沖縄
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-15K08433
[Presentation] アレルギー感作性をin vitroで評価する新しい方法の開発2016
- Author(s)
  溝口出、大橋美緒、長谷川英哲、千葉祐規乃、徐明利、善本隆之
- Organizer
  第5回医薬工3大学包括連携推進シンポジウム
- Place of Presentation
  東京
- Year and Date
  2016-06-18
- Data Source
  KAKENHI-PROJECT-15K07947
[Presentation] Establishment of a novel in vitro evaluation system for the prediction of respiratory sensitizing potential of chemicals.2016
- Author(s)
  Yoshimoto, T., Ohashi, M., Hasegawa, H., Chiba, Y., Xu, M., and Mizoguchi, I.
- Organizer
  ICCA-LRI and NIHS Workshop
- Place of Presentation
  Awaji Island
- Year and Date
  2016-06-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08433
[Presentation] Stop-imatinib CML患者末梢血単核球における免疫関連miRNAの意義2015
- Author(s)
  大屋敷一馬、溝口出、善本隆之、田内哲三、岡部聖一、片桐誠一朗、梅津知宏、大屋敷純子
- Organizer
  第7回血液疾患免疫療法研究会
- Place of Presentation
  東京
- Year and Date
  2015-09-26
- Data Source
  KAKENHI-PROJECT-15K07947
[Presentation] 化学物質の呼吸器感作性in vitro評価法の開発2015
- Author(s)
  溝口出、千葉佑規乃、角田廉、徐明利、善本隆之
- Organizer
  第3期LRI研究報告会
- Place of Presentation
  東京
- Year and Date
  2015-08-28
- Data Source
  KAKENHI-PROJECT-15K07947
[Presentation] 化学物質の呼吸器感作性in vitro評価法の開発2015
- Author(s)
  溝口出、千葉佑規乃、角田廉、徐明利、善本隆之
- Organizer
  第3期LRI研究報告会
- Place of Presentation
  東京
- Year and Date
  2015-08-28
- Data Source
  KAKENHI-PROJECT-15K08433
[Presentation] Binding of Epstein-Barr virus-induced gene 3 to calnexin enhances its chaperone activity and augments interleukin-23 receptor expression, leading to development of colitis.2015
- Author(s)
  Mizoguchi, I., Chiba, Y., Xu, M., and Yoshimoto, T.
- Organizer
  第44回日本免疫学会総会・学術集会
- Place of Presentation
  札幌
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-15K08433
[Presentation] Binding of Epstein-Barr virus-induced gene 3 to calnexin enhances its chaperone activity and augments interleukin-23 receptor expression, leading to development of colitis.2015
- Author(s)
  Mzoguchi, I., Chiba, Y., Xu, M., and Yoshimoto, T.
- Organizer
  第44回日本免疫学会総会・学術集会
- Place of Presentation
  札幌
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-15K07947
[Presentation] 化学物質の呼吸器感作性in vitro評価法の開発2015
- Author(s)
  善本隆之、千葉佑規乃、角田廉、徐明利、溝口出
- Organizer
  第28回日本動物実験代替法学会
- Place of Presentation
  横浜
- Year and Date
  2015-12-10
- Invited
- Data Source
  KAKENHI-PROJECT-15K08433
[Presentation] 化学物質の呼吸器感作性in vitro評価法の開発2015
- Author(s)
  善本隆之、千葉佑規乃、角田廉、徐明利、溝口出
- Organizer
  第28回日本動物実験代替法学会
- Place of Presentation
  横浜
- Year and Date
  2015-12-10
- Invited
- Data Source
  KAKENHI-PROJECT-15K07947
[Presentation] 慢性骨髄性白血病患者における治療中止を成功させるための予測因子2015
- Author(s)
  片桐誠一朗、田内哲三、梅津知宏、田所健一、溝口出、善本隆之、大屋敷純子、大屋敷一馬
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  金沢
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-15K07947
[Presentation] New approach for DC-mediated cancer vaccine using IL-27-expanded myeloid progenitor cells.2013
- Author(s)
  Yoshimoto, T., Mizoguchi, I. Hisada, M., and Mizuguchi, J.
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24370058
[Presentation] IL-6/IL-12ファミリーサイトカインIL-27によるDC前駆細胞の分化・増殖誘導2013
- Author(s)
  古津純一、水戸部佳奈、溝口出、金子幸太郎、角田廉、樋口要、善本隆之
- Organizer
  東京医科大学記念館ポスター発表懇談会
- Place of Presentation
  東京
- Year and Date
  2013-11-28
- Data Source
  KAKENHI-PROJECT-24659595
[Presentation] メラノーマ組織内CD4+T細胞除去による抗腫瘍免疫反応機序の解析2013
- Author(s)
  永井　宏、藤原　進、下浦典子、善本隆之、錦織千佳子
- Organizer
  第２５回日本色素細胞学会学術大会
- Place of Presentation
  大阪大学銀杏会館
- Data Source
  KAKENHI-PROJECT-25461692
[Presentation] IL-27 promotes the differentiation of bone marrow cells into DC progenitor cells2013
- Author(s)
  Furusawa, J., Mizoguchi, I., Mizuguchi, J., and Yoshimoto, T
- Organizer
  第42回日本免疫学会総会
- Place of Presentation
  幕張
- Data Source
  KAKENHI-PROJECT-24659595
[Presentation] サイトカインによる免疫制御法 The percentage of effector populations of NK cells correlated highly with sustained CMR with or without imatinib in chronic myeloid leukemia patients2013
- Author(s)
  善本隆之, Katagiri, S., Mizoguchi, I., Yoshimoto, T., Mizuguchi, J., Ohyashiki, J.H., Tauchi, T., Inokuchi, K., and Ohyashiki, K
- Organizer
  18th Congress of the European Hematology Association
- Place of Presentation
  Stockholm, Sweden
- Data Source
  KAKENHI-PROJECT-24659595
[Presentation] New approach for DC-mediated cancer vaccine using IL-27-expanded myeloid progenitor cells.2013
- Author(s)
  Yoshimoto, T., Mizoguchi, I. Hisada, M., and Mizuguchi, J.
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24659595
[Presentation] EBI3 functions as an intracellular molecule to regulate the development of colitis in naive CD4+CD25- T cells.2013
- Author(s)
  Mizoguchi, I. Mitobe, K., Tsunoda, R., Higuchi, K., Mizuguchi, J., and Yoshimoto, T.
- Organizer
  15th International Congress of Immunology
- Place of Presentation
  Milan, Italy
- Data Source
  KAKENHI-PUBLICLY-25118727
[Presentation] Long-term up-regulation of effector NK cells in CML after stopping imatinib.2013
- Author(s)
  Katagiri, S., Mizoguchi, I., Yoshimoto, T., Ohyashiki, J.H., Tauchi, T., Inokuchi, K., and Ohyashiki, K.
- Organizer
  第75回日本血液学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PUBLICLY-25118727
[Presentation] New approach for DC-mediated cancer vaccine using IL-27-expanded myeloid progenitor cells2013
- Author(s)
  Yoshimoto, T., Mizoguchi, I. Hisada, M., and Mizuguchi, J
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24659595
[Presentation] IL-27によるDC前駆細胞の分化・増殖誘導2013
- Author(s)
  古津純一、溝口出、水戸部佳奈、樋口要、金子幸太郎、角田廉、水口純一郎、久田将之、粕谷和彦、土田明彦、善本隆之
- Organizer
  第90回東京医科大学・東京薬科大学・免疫アレルギー研究会
- Place of Presentation
  東京
- Year and Date
  2013-11-05
- Data Source
  KAKENHI-PROJECT-24659595
[Presentation] EBI3 promotes IL-23-mediated signaling resulting in the development of colitis by enhancing IFN-g production.2013
- Author(s)
  Mizoguchi, I., Mizuguchi, J., and Yoshimoto, T.
- Organizer
  第42回日本免疫学会総会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-24370058
[Presentation] EBI3 functions as an intracellular molecule to regulate the development of colitis in naive CD4^<+>CD25^<-> T cells2013
- Author(s)
  Mizoguchi I, Mitobe K, Tsunoda R, Higuchi K, Mizuguchi J, Yoshimoto, T
- Organizer
  15th International Congress of Immunology
- Place of Presentation
  Milan, Italy
- Data Source
  KAKENHI-PROJECT-23590475
[Presentation] The percentage of effector populations of NK cells correlated highly with sustained CMR with or without imatinib in chronic myeloid leukemia patients.2013
- Author(s)
  Katagiri, S., Mizoguchi, I., Yoshimoto, T., Mizuguchi, J., Ohyashiki, J.H., Tauchi, T., Inokuchi, K., and Ohyashiki, K.
- Organizer
  18th Congress of the European Hematology Association
- Place of Presentation
  Stockholm, Sweden
- Data Source
  KAKENHI-PUBLICLY-25118727
[Presentation] IL-27 promotes the differentiation of bone marrow cells into DC progenitor cells.2013
- Author(s)
  Furusawa, J., Mizoguchi, I., Mizuguchi, J., and Yoshimoto, T.
- Organizer
  第42回日本免疫学会総会
- Place of Presentation
  幕張
- Data Source
  KAKENHI-PROJECT-24659595
[Presentation] New approach for DC-mediated cancer vaccine using IL-27-expanded myeloid progenitor cells.2013
- Author(s)
  Yoshimoto, T., Mizoguchi, I. Hisada, M., and Mizuguchi, J.
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PUBLICLY-25118727
[Presentation] EBI3 functions as an intracellular molecule to regulate the development of colitis in naive CD4+CD25- T cells.2013
- Author(s)
  Mizoguchi, I. Mitobe, K., Tsunoda, R., Higuchi, K., Mizuguchi, J., and Yoshimoto, T.
- Organizer
  第78日本インターフェロン・サイトカイン学会総会(JSICR)/第21回マクロファージ分子細胞生物国際シンポジウム(MMCB)合同学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24370058
[Presentation] Long-term up-regulation of effector NK cells in CML after stopping imatinib2013
- Author(s)
  Katagiri, S., Mizoguchi, I., Yoshimoto, T., Ohyashiki, J.H., Tauchi, T., Inokuchi, K., and Ohyashiki, K
- Organizer
  第75回日本血液学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24659595
[Presentation] The percentage of effector populations of NK cells correlated highly with sustained CMR with or without imatinib in chronic myeloid leukemia patients2013
- Author(s)
  Katagiri S, Mizoguchi I, Yoshimoto T, Mizuguchi J, Ohyashiki JH, Tauchi T, Inokuchi K, Ohyashiki K
- Organizer
  18th Congress of the European Hematology Association
- Place of Presentation
  Stockholm, Sweden
- Data Source
  KAKENHI-PROJECT-23590475
[Presentation] EBI3 functions as an intracellular molecule to regulate the development of colitis in naive CD4+CD25- T cells.2013
- Author(s)
  Mizoguchi, I. Mitobe, K., Tsunoda, R., Higuchi, K., Mizuguchi, J., and Yoshimoto, T.
- Organizer
  15th International Congress of Immunology
- Place of Presentation
  Milan, Italy,
- Data Source
  KAKENHI-PROJECT-24370058
[Presentation] 癌DCワクチン療法への応用を目指したIL-27を用いたDC前駆細胞の分化・増殖誘導法の開発2013
- Author(s)
  古津純一、溝口出、水戸部佳奈、樋口要、金子幸太郎、角田廉、水口純一郎、久田将之、粕谷和彦、土田明彦、善本隆之
- Organizer
  医薬工3大学包括的連携推進シンポジウム
- Place of Presentation
  東京
- Year and Date
  2013-12-14
- Data Source
  KAKENHI-PROJECT-24659595
[Presentation] The percentage of effector populations of NK cells correlated highly with sustained CMR with or without imatinib in chronic myeloid leukemia patients.2013
- Author(s)
  Katagiri, S., Mizoguchi, I., Yoshimoto, T., Mizuguchi, J., Ohyashiki, J.H., Tauchi, T., Inokuchi, K., and Ohyashiki, K.
- Organizer
  18th Congress of the European Hematology Association
- Place of Presentation
  Stockholm, Sweden
- Data Source
  KAKENHI-PROJECT-24370058
[Presentation] IL-27 promotes the differentiation of bone marrow cells into DC progenitor cells.2013
- Author(s)
  Furusawa, J., Mizoguchi, I., Mizuguchi, J., and Yoshimoto, T.
- Organizer
  第42回日本免疫学会総会
- Place of Presentation
  幕張
- Data Source
  KAKENHI-PUBLICLY-25118727
[Presentation] Long-term up-regulation of effector NK cells in CML after stopping imatinib.2013
- Author(s)
  Katagiri, S., Mizoguchi, I., Yoshimoto, T., Ohyashiki, J.H., Tauchi, T., Inokuchi, K., and Ohyashiki, K.
- Organizer
  第75回日本血液学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24659595
[Presentation] Efficient antigen presentation and induction of anti-tumor immunity by dendritic cells loaded with antigens by electroporation2012
- Author(s)
  Nagaoka K, Takahara M, Yoshimoto T, Teruya T, Shiroma H, Maekawa R
- Organizer
  American Association of Cancer (AACR) Annual Meeting 2012
- Place of Presentation
  Chicago, IL, USA
- Data Source
  KAKENHI-PROJECT-23590475
[Presentation] EBI3(Epstein-Barr virus-induced gene-3) ノックアウトマウスにおける精巣免疫微小環境について2012
- Author(s)
  寺山　隼人, 平井　宗一，　曲　　　寧，　畑山　直之，　平柳　淑恵，　内藤　宗和，　善本　隆之，　伊藤　正裕
- Organizer
  第27回日本生殖免疫学会総会・学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-24590243
[Presentation] エレクトロポレーション法で抗原導入した樹状細胞は高い抗原提示能を有し、生体内投与により高い抗腫療効果を示す2012
- Author(s)
  長岡孝治、高原将司、三木健次、善本隆之、照屋剛、城間寛、神垣隆、前川隆司
- Organizer
  第22回日本樹状細胞研究会
- Place of Presentation
  福島
- Year and Date
  2012-06-15
- Data Source
  KAKENHI-PROJECT-24659595
[Presentation] Activation levels of natural killer cells and CD8^+ T cells correlate highly with sustained complete molecular response after discontinuation of imatinib in chronic myeloid leukemia patients2012
- Author(s)
  Katagiri, S., Mizoguchi, I., Yoshimoto, T., Mizuguchi, J., Ohyashiki, J.H., and Ohyashiki, K
- Organizer
  2012 ASH Annual Meeting and Exposition
- Place of Presentation
  Atlanta GA, USA
- Data Source
  KAKENHI-PROJECT-24659595
[Presentation] IL-27とPoly(I : C)による協調的TRAILとTLR3発現増強を介したメラノーマ腫療増殖のTRAIL依存的抑制2012
- Author(s)
  溝口出、千葉祐規乃、徐明利、樋口要、水口純一郎、善本隆之
- Organizer
  第87回東京医科大学・東京薬科大学・免疫アレルギー研究会
- Place of Presentation
  東京
- Year and Date
  2012-05-29
- Data Source
  KAKENHI-PROJECT-24659595
[Presentation] Activation levels of NK and CD8+ T cells correlate with sustained CMR after discontinuation of imatinib in CML patients.2012
- Author(s)
  Yoshimoto, T. et al.
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24659595
[Presentation] IL-27とPoly(1:c)による協調的TRAILとTLR3発現増強を介したメラノーマ腫瘍増殖のTRAIL依存的抑制2012
- Author(s)
  溝口出、千葉祐規乃、徐明利、樋口要、善本隆之、水口純一郎
- Organizer
  第87回東京医科大学・東京薬科大学・免疫アレルギー研究会
- Place of Presentation
  東京
- Year and Date
  2012-05-29
- Data Source
  KAKENHI-PROJECT-23590475
[Presentation] Dendritic cells loaded with antigen by electroporation induce strong anti-tumor immunity in vivo2012
- Author(s)
  Nagaoka, K., Miki, K., Yoshimoto, T., Teruya, T., Shiroma, H., and Maekawa, R
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24659595
[Presentation] Role of intratesticular Epstein-Barr virus-induced genen-3 (EBI3) in the mouse2012
- Author(s)
  Terayama H, Hirai S, Qu N, Hirayanagi Y, Musha M, Naito M, Yoshimoto T, Itoh M
- Organizer
  The Japan Society of Andrology The 31st Annual Meeting & The 18^<th> Japanese Testis Workshop
- Place of Presentation
  Kobe, Japan
- Data Source
  KAKENHI-PROJECT-23590475
[Presentation] Induction of nitric oxide by macrophages stimulated with IL-27 and lipopolysaccaride through STAT1, NF-kB and MAPKs2012
- Author(s)
  Shimizu, M., Mizoguchi, I., Mizuguchi, J., and Yoshimoto, T
- Organizer
  第41回日本免疫学会総会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24659595
[Presentation] Activation levels of natural killer cells and CD8^<+> T cells correlate highly with sustained complete molecular response after discontinuation of imatinib in chronic myeloid leukemia patients2012
- Author(s)
  Katagiri S, Mizoguchi I, Yoshimoto T, Mizuguchi J, Ohyashiki JH, Ohyashiki K
- Organizer
  2012 ASH Annual Meeting and Exposition
- Place of Presentation
  Atlanta GA, USA
- Data Source
  KAKENHI-PROJECT-23590475
[Presentation] Cooperative growth inhibition of human melanomas by IL-27 and a TLR3 agonist poly(I : C) in TRAIL-dependent manner2012
- Author(s)
  Mizoguchi, I., Mizuguchi, J., and Yoshimoto, T
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24659595
[Presentation] Activation levels of NK and CD8^+ T cells correlate with sustained CMR after discontinuation of imatinib in CML patients2012
- Author(s)
  Yoshimoto, T., Mizoguchi, I., Katagiri, S., Mizuguchi, J., Ohyashiki, J., and Ohyashiki, K
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24659595
[Presentation] DCワクチンをリンパ節投与した際の局所滞留性と免疫誘導能の検討2012
- Author(s)
  太田裕士、徐明利、溝口出、高梨正勝、須藤カツ子、黒田雅彦、善本隆之、粕谷和彦、土田明彦、畝崎栄
- Organizer
  第132年会日本薬学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24659595
[Presentation] Activation levels of NK and CD8^+ T cells correlate with sustained CMR after discontinuation of imatinib in CML patients2012
- Author(s)
  Yoshimoto, et al.
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Year and Date
  2012-09-21
- Data Source
  KAKENHI-PROJECT-24370058
[Presentation] Comparison of antigen-loading methods into dendritic cells with protein, mRNA or peptides derived ovalbumin for antigen presenting activity2012
- Author(s)
  Nagaoka, K., Miki, K., Yoshimoto, T., Kamigaki, T., and Maekawa, R
- Organizer
  The 12^<th> International Symposium on Dendritic Cells
- Place of Presentation
  Daegu, Korea
- Data Source
  KAKENHI-PROJECT-24659595
[Presentation] DCワクチンをリンパ節投与した際の局所滞留性と免疫誘導能の検討2012
- Author(s)
  太田裕士、徐明利、溝口出、高梨正勝、須藤カツ子、黒田雅彦、善本隆之、粕谷和彦、土田明彦、畝崎榮
- Organizer
  第132年会日本薬学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23590475
[Presentation] Comparison of antigen-loading methods into dendritic cells with protein, mRNA or peptides derived ovalbumin for antigen presenting activity2012
- Author(s)
  Nagaoka K, Miki K, Yoshimoto T, Kamigaki T, Maekawa R
- Organizer
  The 12th International Symposium on Dendritic Cells
- Place of Presentation
  Daegu, Korea
- Data Source
  KAKENHI-PROJECT-23590475
[Presentation] Efficient antigen presentation and induction of anti-tumor immunity by dendritic cells loaded with antigens by electroporation2012
- Author(s)
  Nagaoka, K., Takahara,M., Yoshimoto, T., Teruya, T., Shiroma, H., and Maekawa, R
- Organizer
  American Association of Cancer (AACR) Annual Meeting 2012
- Place of Presentation
  Chicago, IL, USA
- Data Source
  KAKENHI-PROJECT-24659595
[Presentation] Interleukin-17 and interleukin-27 exert opposite effects on tumor necrosis factor-alpha -mediated psoriasis related chemokine production in human keratinocytes2012
- Author(s)
  Susumu Fujiwara, Hiroshi Nagai, Shuntaro Oniki, Takayuki Yoshimoto, and Chikako Nishigori
- Organizer
  2ndEasetern Asia Dermatology Congress
- Place of Presentation
  Beijing, China
- Data Source
  KAKENHI-PROJECT-22591220
[Presentation] IL-17 versus IL-27 : opposite effects on TNF-α-induced chemokine production in human keratinocytes2011
- Author(s)
  Fujiwara S, Nagai H, Oniki S, Yoshimoto T, Nishigori C
- Organizer
  日本研究皮膚科学会第36回年次学術大会・総会
- Place of Presentation
  国立京都国際会館(京都府)
- Year and Date
  2011-12-09
- Data Source
  KAKENHI-PROJECT-22591220
[Presentation] IL-17 versus IL-27: Opposite effects on tumor necrosis factor-alpha-mediated chemokine production in human keratinocytes2011
- Author(s)
  Susumu Fujiwara, Hiroshi Nagai, Shuntaro Oniki, Takayuki Yoshimoto, and Chikako Nishigori
- Organizer
  日本研究皮膚科学会第36回年次学術大会・総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22591220
[Presentation] IL-27 enhances poly(I:C)-inducedapoptosisoftumorcells2011
- Author(s)
  Chiba Y, Xu M, Mizoguchi I, Mizuguchi J, Yoshimoto T
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-23590475
[Presentation] サイトカインによる免疫制御2011
- Author(s)
  善本隆之
- Organizer
  第34回東京医科大学・医科学フォーラム
- Place of Presentation
  東京
- Year and Date
  2011-02-22
- Data Source
  KAKENHI-PROJECT-20370049
[Presentation] Regulation of the development of acute hepatitis by IL-23 through IL-22 and IL-17 production2011
- Author(s)
  Xu M, Morishima N, Mizoguchi I, Chiba Y, Fujita K, Kuroda M, Iwakura Y, Cua DJ, Yasutomo K, Mizuguchi J, Yoshimoto T
- Organizer
  第168回東京医科大学医学会総会
- Place of Presentation
  東京
- Year and Date
  2011-11-05
- Data Source
  KAKENHI-PROJECT-23590475
[Presentation] Regulation of inflammatory immune responses leading to the development of bone destructive autoimmune disease rheumatoid arthritis by IL-27. Bio-Rhematology Internation Congress (BRIC) Tokyo2011
- Author(s)
  Yoshimoto T, Xu M, Mizoguchi I, Chiba Y, Kamiya S, Matsui M, Shahrara S, Mizuguchi J
- Organizer
  The 8the GARN Meeting
- Place of Presentation
  Chiba, Japan
- Data Source
  KAKENHI-PROJECT-23590475
[Presentation] Regulation of the development of acute hepatitis by IL-23 through IL-22 and IL-17 production2011
- Author(s)
  Xu M, Morishima N, Mizoguchi I, Chiba Y, Fujita K, Kuroda M, Iwakura Y, Cua DJ, Yasutomo K, Mizuguchi J, Yoshimoto T
- Organizer
  The 98th American Association of Immunologists Annual Meeting
- Place of Presentation
  San Francisco, California, USA
- Data Source
  KAKENHI-PROJECT-23590475
[Presentation] IL-6/IL-12関連ヘテロダイマーサイトカインによる免疫制御と治療応用2011
- Author(s)
  善本隆之
- Organizer
  第1回東京医科大学・東京薬科大学生命科学部合同シンポジウム
- Place of Presentation
  東京
- Year and Date
  2011-01-29
- Data Source
  KAKENHI-PROJECT-20370049
[Presentation] Antitumor activity of IL-27 by augmentation of histocompatibility antigens.2010
- Author(s)
  Shimizu M., Mizuguchi J., Yoshimoto T.
- Organizer
  14^<th> International Congress of Immunology
- Place of Presentation
  Kobe, Japan
- Data Source
  KAKENHI-PROJECT-20370049
[Presentation] IL-27の抗腫瘍作用におけるマクロファージの役割2010
- Author(s)
  清水本武、佐藤真友美、小倉潔、武田康隆、水口純一郎、善本隆之
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20370049
[Presentation] IL-27 induces rapid up-regulation of Notch l expression critical for IL-10 production in CD4^+ T cells.2010
- Author(s)
  Morishima N., Xu M., Mizoguchi I., Chiba Y., Yasutomo K., Mizuguchi J., Yoshimoto T.
- Organizer
  14^<th> International Congress of Immunology
- Place of Presentation
  Kobe, Japan
- Data Source
  KAKENHI-PROJECT-20370049
[Presentation] A protective role for IL-23 in acute hepatitis model by inducing IL-22 production.2010
- Author(s)
  Xu M., Morishima N., Mizoguchi I., Chiba Y., Fujita K., Kuroda M., Cua D.J., Yasutomo K., Mizuguchi J., Yoshimoto T.
- Organizer
  14^<th> International Congress of Immunology
- Place of Presentation
  Kobe, Japan
- Data Source
  KAKENHI-PROJECT-20370049
[Presentation] Plasmacytoid dendritic cells are crucial for Th17 differentiation.2009
- Author(s)
  Ishifune C., Maekawa Y., Yoshimoto T., Yasutomo K.
- Organizer
  The 96^<th> Annual Meeting of The American Association of Immunologists.
- Place of Presentation
  Seattle, Washington
- Data Source
  KAKENHI-PROJECT-20370049
[Presentation] IL-27による組織適合抗原の発現上昇と抗腫瘍機構の解析2009
- Author(s)
  清水本武、佐藤真友美、小倉潔、武田康隆、水口純一郎、善本隆之
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20370049
[Presentation] Regulation of Th cell differentiation by IL-23p19 produced by activated CD4^+ T cells.2009
- Author(s)
  Chiba Y, Mizoguchi I., Mizuguchi J., Yoshimoto T.
- Organizer
  第39回日本免疫学会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20370049
[Presentation] IL-27はNK細胞を活性化しADCCを介してNK抵抗性頭頸部扁平上皮癌を抑制する2009
- Author(s)
  松井雅裕、岸田綱郎、中野宏、吉本公一郎、新屋政春、島田剛敏、中井茂、今西二郎、善本隆之、久育男、松田修
- Organizer
  第72回日本インターフェロン・サイトカイン学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20370049
[Presentation] IL-27による組織適合抗原と抗腫瘍作用の増強2009
- Author(s)
  清水本武、水口純一郎、善本隆之
- Organizer
  第39回日本免疫学会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20370049
[Presentation] IL-27 suppresses RANKL expression in CD4^+ T cells partly through STAT3.2009
- Author(s)
  Kamiya S., Okumura M., Chiba Y, Fukawa T., Nakamura C., Nimura N., Mizuguchi J., Yoshimoto T., Wada S.
- Organizer
  ASBMR 31^<st> Annual Meeting.
- Place of Presentation
  Denver, Colorado
- Data Source
  KAKENHI-PROJECT-20370049
[Presentation] Potent immune regulatory activity of IL-10^|IFN-y^| Tr1 cells induced and expanded by IL-27 and TGF-β.2009
- Author(s)
  Yoshimoto T., Morishima N., Onishi K., Torii M., Kato T., Mizuguchi J.
- Organizer
  Keystone Symposia on Regulatory T Cells.
- Place of Presentation
  Keystone, Colorado
- Data Source
  KAKENHI-PROJECT-20370049
[Presentation] IL-27はNK細胞を活性化しADCCを介してNK抵抗性頭頸部扁平上皮癌を抑制する2009
- Author(s)
  松井雅裕、岸田綱郎、中野宏、吉本公一郎、新屋政春、島田剛敏、中井茂,今西二郎、善本隆之、久育男、松田修
- Organizer
  第39回日本免疫学会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20370049
[Presentation] IL-33 mediated expulsion of Nippostrongylus brasiliensis in the absence of adaptive immune system.(シンポジウム)2009
- Author(s)
  安田好文、佐々木由紀、松本真琴、善本知広、中西憲司
- Organizer
  第78回日本寄生虫学会大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] IL-18 とアレルギー性炎症-IL-18による自然型アレルギーと獲得型アレルギー、(特別講演)2009
- Author(s)
  善本知広
- Organizer
  第17回大分アレルギー講習会
- Place of Presentation
  大分
- Year and Date
  2009-03-07
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] Brand-new prevention method of postoperative adhesion formation used by HGF. (Symposium)2009
- Author(s)
  Kosaka H, Yoshimoto T, Nakanishi K, and Fujimoto J.
- Organizer
  Academic Surgical Congress
- Place of Presentation
  Fort Myers, Florida
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] Analysis of antitumor activity of IL-2.2008
- Author(s)
  Shimizu, M., Sato, M., Ogura, K., Nishito, Y., Takeda, Y., Mizuguchi, J, Yoshimoto, T.
- Organizer
  The 67^<th> Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Nagoya
- Data Source
  KAKENHI-PROJECT-19590418
[Presentation] 好塩基球はIL-4産生能と抗原提示能の両機能を持ち生体内でTh2応答を誘導, 維持,増強する. (シンポジウム)2008
- Author(s)
  善本知広、小坂久、大橋浩一郎、中西憲司
- Organizer
  「免疫難病・感染症等の先進医療技術」第5回(最終)公開シンポジウム
- Place of Presentation
  東京
- Year and Date
  2008-12-15
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] IL-27による抗腫瘍機構の解析2008
- Author(s)
  清水本武、佐藤真友美、小倉潔、西籐泰昌、武田康隆、水口純一郎、善本隆之
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20370049
[Presentation] HGFを用いた術後腹腔内癒着形成予防法2008
- Author(s)
  小坂久, 善本知広, 中西憲司藤元治朗
- Organizer
  第50回日本消化器病学会大会
- Place of Presentation
  東京
- Year and Date
  2008-10-01
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] Role of NKT cell-driven IFN-γ in postoperative adhesion formation.2008
- Author(s)
  Kosaka H, Yoshimoto T, Nakanishi K, and Fujimoto, J.
- Organizer
  Digestive Disease Week and the 109th Annual Meeting of the AGA Institute DDW
- Place of Presentation
  San Diego, U.S.A.
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] IL-33とアレルギー炎症IL-33の自然型及び獲得型アレルギー性炎症に対する生理作用2008
- Author(s)
  善本知広
- Organizer
  第4回日本免疫学会, 理研免疫アレルギーセンター(RCAI)免疫ワークショップ
- Place of Presentation
  甲府
- Year and Date
  2008-05-20
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] Administration of IL-33 induces airway hyperresponsiveness and goblet cell hyperplasia in the lungs in the absence of adaptive immune system2008
- Author(s)
  Kondo Y, Yoshimoto T, YasudaK, Fujimoto J., Nakanishi K.
- Organizer
  第38回日本免疫学会総会・学術集会
- Place of Presentation
  京都
- Year and Date
  2008-12-03
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] IFN-γ is a therapeutic target molecule for prevention of postoperative adhesion formation. (シンポジウム)2008
- Author(s)
  Yoshimoto T, Kosaka H, Fujimoto J, and Nakanishi K.
- Organizer
  第38回日本免疫学会総会・学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] IL-33のマウス生体内投与は獲得免疫応答非依存性にNippostrongylus brasiliensis排虫作用を有する杯細胞を誘導する2008
- Author(s)
  安田好文, 佐々木由紀, 近藤祐一, 松本真琴, 善本知広, 中西憲司
- Organizer
  第73回日本インターフェロン・サイトカイン学会学術集会
- Place of Presentation
  北海道大学、札幌
- Year and Date
  2008-07-10
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] IL-27による新規抗アレルギー作用IL-27による気管支喘息とアレルギー性結膜炎発症の抑制2008
- Author(s)
  善本知広, 松葉沙織, 中西憲司
- Organizer
  第20回日本アレルギー学会春季臨床大会
- Place of Presentation
  横浜
- Year and Date
  2008-06-12
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] Plasmacytoid dendritic cells are crucial for Th17 differentiation.2008
- Author(s)
  Ishifune C., Maekawa Y., Yoshimoto T., Yasutomo, K.
- Organizer
  第38回日本免疫学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20370049
[Presentation] Basophils induce and augment Th2 response2008
- Author(s)
  Nakanishi, K., Yoshimoto, T
- Organizer
  第38回日本免疫学会総会・学術集会
- Place of Presentation
  京都
- Year and Date
  2008-12-01
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] In vivo administration of IL-33 induces goblet cells capable of expelling Nippostrongylus brasiliensis in the absence of a daptive immune system2008
- Author(s)
  Yasuda K, Sasaki Y, Kondo Y, Matsumoto M, Yoshimoto T., Nakanishi K
- Organizer
  The 8^<th> Awaji International Forum on Infecti on and Immunity
- Place of Presentation
  淡路島、兵庫
- Year and Date
  2008-09-07
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] 正電荷ポリマーを用いたFasリガンド(FasL)遺伝子導入による乳癌遺伝子治療に向けた基礎的研究2008
- Author(s)
  武田泰隆, 榮光子, 善本隆之, 森本純司, 清水本武, 柳衛宏宣, 螺良愛朗
- Organizer
  第18回乳癌基礎研究会
- Place of Presentation
  福島
- Data Source
  KAKENHI-PROJECT-19590418
[Presentation] Administration of IL-33 induces airway hyperresponsiveness and goblet cell hyperplasia in the lungs in the absence of adoptive immune system、(ワークショップ)2008
- Author(s)
  Kondou Y, Yoshimoto T, Yasuda K, Fujimoto, J. and Nakanishi K.
- Organizer
  第38回日本免疫学会総会・学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] IL-1ファミリーサイトカインと自然型アトピー性炎症、(シンポジウム)2008
- Author(s)
  中西憲司、善本知広
- Organizer
  第58回日本アレルギー学会秋季学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] Inhibition of RANKL expression in CD4^+ T cells by IL-27 partially through STAT3 dependent mechanism.2008
- Author(s)
  Chiba Y., Kamiya S., Mizuguchi J., Yoshimoto T.
- Organizer
  第38回日本免疫学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20370049
[Presentation] IL-33で刺激されたマスト細胞は制御性T細胞の増幅を介して炎症抑性能を発揮する2008
- Author(s)
  大保木啓介、大野建州、梶原直樹、須藤カツ子、善本隆之、須藤一、奥村康、小川秀興、齋藤博久、中江進
- Organizer
  第38回日本免疫学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20370049
[Presentation] T細胞の異常とアレルギー : IL-18によるSuper Th1細胞の誘導とIL-33によるTh2細胞増強作用、(特別シンポジウム)2008
- Author(s)
  善本知広、中西憲司
- Organizer
  第58回日本アレルギー学会秋季学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] IL-27とTGF-β1刺激による効果的なIL-10産生Tr1細胞の誘導と増幅2008
- Author(s)
  森嶋紀子、鳥井美江、加藤琢磨、水口純一郎、善本隆之
- Organizer
  第38回日本免疫学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20370049
[Presentation] 実験的アレルギー性結膜炎モデルにおけるIL-33の病因論的役割の解明2008
- Author(s)
  松葉沙織, 善本知広, 杉村和久, 伊藤祐二, 北本祥, 森本麻衣, 三村治, 中西憲司
- Organizer
  「免疫難病・感染症等の先進医療技術」第5回(最終)公開シンポジウム
- Place of Presentation
  東京
- Year and Date
  2008-12-15
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] IL-33のマウス生体内投与はNippostrongylus brasiliensis排虫作用を有する杯細胞を誘導する2008
- Author(s)
  安田好文, 佐々木由紀, 近藤祐一, 松本真琴, 善本知広, 中西憲司.
- Organizer
  第77回日本寄生虫学会大会
- Place of Presentation
  長崎
- Year and Date
  2008-04-03
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] 新規DC免疫法 : 抗原とアジュバントでパルスした樹状細胞はナイーブマウスに迅速かつ顕著なTh2応答を誘導する2008
- Author(s)
  今井康友, 安田好文, 今村美智子, 林伸樹, 善本知広, 山西清文, 筒井ひろ子, 水谷仁, 中西憲司
- Organizer
  「免疫難病・感染症等の先進医療技術」第5回(最終)公開シンポジウム
- Place of Presentation
  東京
- Year and Date
  2008-12-15
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] 実験的アレルギー性結膜炎モデルにおけるIL-33の病因論的役割の解明. (シンポジウム)2008
- Author(s)
  松葉沙織、善本知広、三村治、中西憲司
- Organizer
  「免疫難病・感染症等の先進医療技術」第5回(最終)公開シンポジウム
- Place of Presentation
  東京
- Year and Date
  2008-12-15
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] T細胞の異常とアレルギーIL-18によるSuper Th1細胞の誘導とIL-33によるTh2細胞増強作用2008
- Author(s)
  善本知広, 中西憲司
- Organizer
  第58回日本アレルギー学会秋季学術大会
- Place of Presentation
  東京
- Year and Date
  2008-11-27
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] IL-33とアレルギー炎症、(招待講演)2008
- Author(s)
  善本知広
- Organizer
  第4回日本免疫学会/理研免疫アレルギー研究センター免疫ワークショップ
- Place of Presentation
  甲府
- Year and Date
  2008-05-20
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] Role of NKT cell-driven IFN-γ in postoperative adhesion formation2008
- Author(s)
  Kosaka H, Yoshimoto T, Nakanishi K., Fujimoto J.
- Organizer
  Digestive Disease Week and the 109th Annual Meeting of the AGA Institute DDW
- Place of Presentation
  San Diego, U.S.A.
- Year and Date
  2008-05-18
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] 術後癒着形成はIFN-γ/STAT1依存性のPAI亢進による2008
- Author(s)
  小坂久, 善本知広, 中西憲司, 藤元治朗
- Organizer
  第108回日本外科学会定期学術集会
- Place of Presentation
  東京
- Year and Date
  2008-05-15
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] IL-33は獲得免疫応答の関与なしに自然型気管支喘息を誘導する2008
- Author(s)
  善本知広
- Organizer
  第73回日本インターフェロン・サイトカイン学会学術集会
- Place of Presentation
  北海道大学、札幌
- Year and Date
  2008-07-10
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] IL-12.IL-17 axisによるウイルス感染防御における増強機構の解析2008
- Author(s)
  高山俊輔、大野悟史、磯田明宏、守屋修、林秀徳、岩倉洋一郎、善本隆之、赤塚俊隆、松井政則
- Organizer
  日本薬学会第128年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-20370049
[Presentation] Analysis of in vivo antitumor activity of IL-27 against melanoma2008
- Author(s)
  Shimizu. M., Mizuguchi, J, Yoshimoto, T
- Organizer
  The 38^<th> Annual Meeting of the Japanese society for immunology
- Place of Presentation
  Kyoto, Kyoto International Conference Center
- Data Source
  KAKENHI-PROJECT-19590418
[Presentation] ブタクサ花粉特異的実験的アレルギー性結膜炎に対するIL-33の病因的役割の解析2008
- Author(s)
  松葉沙織, 善本知広, 安田好文, 池田誠宏, 三村治, 中西憲司
- Organizer
  第38回日本免疫学会総会・学術集会
- Place of Presentation
  京都
- Year and Date
  2008-12-01
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] IL-1ファミリーサイトカインと自然型アトピー性炎症2008
- Author(s)
  中西憲司, 善本知広
- Organizer
  第58回日本アレルギー学会秋季学術大会
- Place of Presentation
  東京
- Year and Date
  2008-11-28
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] 気道炎症疾患と自然免疫 : IL-18/IL-33による自然型気管支喘息の誘導2008
- Author(s)
  善本知広, 中西憲司
- Organizer
  第58回日本アレルギー学会秋季学術大会
- Place of Presentation
  東京
- Year and Date
  2008-11-28
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] 腹腔内術後癒着形成メカニズムの解明と予防2008
- Author(s)
  小坂久, 善本知広, 中西憲司藤元治朗
- Organizer
  第63回日本消化器外科学会総会
- Place of Presentation
  札幌
- Year and Date
  2008-07-16
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] IFN-γ is a therapeutic target molecule for prevention of post operative adhesion formation2008
- Author(s)
  Yoshimoto T, Kosaka H, Fujimoto J., Nakanishi K.
- Organizer
  第38回日本免疫学会総会・学術集会
- Place of Presentation
  京都
- Year and Date
  2008-12-03
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] 気道炎症疾患と自然免疫 : IL-18/IL-33による自然型気管支喘息の誘導、(シンポジウム)2008
- Author(s)
  善本知広、中西憲司
- Organizer
  第58回日本アレルギー学会秋季学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] IgE抗体産生能を欠くCD40KOマウスハヴェネズエラ糞線虫(Strongyloides venezuelensis : Sv)排中機能が低下している2008
- Author(s)
  佐々木由紀, 安田好文, 善本知広, 中西憲司
- Organizer
  第77回日本寄生虫学会大会
- Place of Presentation
  長崎
- Year and Date
  2008-04-03
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] RW特異的T細胞株を用いたアレルギー性結膜炎モデル : IL-33の病因的役割の解析2008
- Author(s)
  松葉沙織, 善本知広, 安田好文池田誠宏, 三村治, 中西憲司
- Organizer
  第20回日本アレルギー学会春季臨床大会
- Place of Presentation
  横浜
- Year and Date
  2008-06-12
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] IL-33は獲得免疫応答の関与なしに自然型気管支喘息を誘導する、(シンポジウム)2008
- Author(s)
  善本知広
- Organizer
  第73回日本インターフェロン・サイトカイン学会学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] 好塩基球はIL-4産生能と抗原提示能の両機能を持ち生体内でTh2応答を誘導, 維持, 増強する2008
- Author(s)
  善本知広, 小坂久, 大橋浩一郎, 中西憲司
- Organizer
  「免疫難病・感染症等の先進医療技術」第5回(最終)公開シンポジウム
- Place of Presentation
  東京
- Year and Date
  2008-12-15
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] In vivo administration of IL-33 induces goblet cells capable of expelling Nippostrongylus brasiliensis in the absence of adaptive immune system.2008
- Author(s)
  Yasuda K, Sasaki Y, Kondo Y, Matsumoto M, Yoshimoto T, and Nakanishi K.
- Organizer
  The 8^<th> Awaji International Forum on Infection and Immunity
- Place of Presentation
  Hyogo, Japan
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] Analysis of antitumor activity of IL-272008
- Author(s)
  Shimizu, M., Sato, M., Ogura, K. Nishito, Y., Takeda, Y., Mizuguchi, J, Yoshimoto, T
- Organizer
  The 67^<th> Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Nagoya, Nagoya Congress Center
- Data Source
  KAKENHI-PROJECT-19590418
[Presentation] IL-27によるメラノーマに対するin vivo抗腫瘍機構の解析2008
- Author(s)
  清水本武、水口純一郎、善本隆之
- Organizer
  第38回日本免疫学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20370049
[Presentation] Analysis of in vivo antitumor activity of IL-27 against melanoma.2008
- Author(s)
  Shimizu, M., Mizuguchi, J, Yoshimoto, T.
- Organizer
  The 38^<th> Annual Meeting of the Japanese society for immunology.
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-19590418
[Presentation] In vivo administration of IL-33 induces goblet cells capable of expelling Nippostrongylus brasiliensis in the absence of adaptive immune system2008
- Author(s)
  Yasuda K, Sasaki Y, Kondo Y, Matsumoto M, Yoshimoto T., Nakanishi K
- Organizer
  第38回日本免疫学会総会・学術集会
- Place of Presentation
  京都
- Year and Date
  2008-12-03
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] Role of macrophages and neutrophils in antitumor activity of Fas lig and (CD95L)-expressing tumor2007
- Author(s)
  Shimizu. M., Sato, M., Ogura, K. Takeda, Y., Mizuguchi J., Yoshimoto
- Organizer
  The 66^<th>Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-19590418
[Presentation] IL-33は正常マウスに杯細胞を誘導し、Nippostrongylus brasiliensis排虫作用を誘導できる2007
- Author(s)
  安田好文, 佐々木由紀, 松本真琴, 善本知広, 中西憲司
- Organizer
  第37回日本免疫学会総会・学術集会
- Place of Presentation
  東京
- Year and Date
  2007-11-22
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] アレルギー性結膜炎に対するIL-33の病因的役割の基礎的解析2007
- Author(s)
  松葉沙織, 善本知広, 安由好文, 池田誠宏, 三村治, 中西憲司
- Organizer
  第35回日本臨床免疫学会総会
- Place of Presentation
  大阪
- Year and Date
  2007-10-19
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] Lipopolysaccharide induction of IgE by innate type 2 basophils.2007
- Author(s)
  Yoshimoto T. and Nakanishi K.
- Organizer
  2007 Keystone Symposia Conference.
- Place of Presentation
  Colorado, U.S.A.
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] IL-18を標的としたTh1型アレルギー性炎症の治療的戦略、(シンポジウム)2007
- Author(s)
  善本知広
- Organizer
  第57回日本アレルギー学会秋季学術大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] IL-18を標的としたアレルギー性炎症の制御2007
- Author(s)
  安田好文, 善本知広, 今村美智子, 筒井ひろ子, 杉村和久, 中西憲司
- Organizer
  CREST「免疫難病・感染症等の先進医療技術」第4回公開シンポジウム
- Place of Presentation
  東京
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] IL-18を標的としたTh1型アレルギー性炎症の治療的戦略2007
- Author(s)
  善本知広
- Organizer
  第57回日本アレルギー学会秋季学術大会
- Place of Presentation
  横浜
- Year and Date
  2007-11-02
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] マウスに移入された抗原とAlumでパルスされたDCはTh2細胞をCaspase-1非依存性に誘導する2007
- Author(s)
  今井康友, 安田好文, 林伸樹, 松本真琴, 善本知広, 水谷仁, 中西憲司
- Organizer
  第57回日本アレルギー学会秋季学術大会
- Place of Presentation
  横浜
- Year and Date
  2007-11-03
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] NKT細胞由来のIFN-γを中心とした術後癒着形成に関わる免疫学的要因の解析2007
- Author(s)
  小坂久, 善本知広, 藤元治朗, 中西憲司
- Organizer
  第35回日本臨床免疫学会総会
- Place of Presentation
  大阪
- Year and Date
  2007-10-19
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] Establishment of experimental surgical adhesion model and analysis of immunological mechanism underlying organ adhesion.2007
- Author(s)
  Kosaka H, Yoshimoto T, Nakanishi K, and Fujimoto J.
- Organizer
  42nd Congress of the European Society for Surgical Research (ESSR).
- Place of Presentation
  Rotterdam, The Netherlands
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] IL-27 suppresses Th2 cell development as well as Th2 cytokines production from polarized Th2 cells; a novel therapeutic way for Th2-mediated allergic inflammation. (ワークショップ)2007
- Author(s)
  Yoshimoto T, Yoshimoto T, Yasuda K, Mizoguchi J, and Nakanishi K.
- Organizer
  第37回日本免疫学会総会・学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] Role of chemokines in antitumor activity of Fas ligand (CD95L)-expressing tumor.2007
- Author(s)
  Shimizu, M., Mizuguchi, J., Yoshimoto, T.
- Organizer
  第37回日本免疫学会総会・学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590418
[Presentation] NKT細胞由来のIFN-γを中心とした術後癒着形成に関わる免疫学的要因の解析、(ワークショップ)2007
- Author(s)
  小坂久、善本知広、藤元治朗、中西憲司
- Organizer
  第35回日本臨床免疫学会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] Role of macrophages and neutrophils in antitumor activity of Fas ligand (CD95L)-expressing tumor.2007
- Author(s)
  Shimizu, M., Sato, M., Ogura, K., Takeda, Y., Mizuguchi, J, Yoshimoto, T.
- Organizer
  The 66^<th> Annual Meeting of the Japanese Cancer Association.
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-19590418
[Presentation] Role of chemokines in antitumor activity of Fas ligand (CD95L)-expressing tumor2007
- Author(s)
  Shimizu, M., Sato, M., Ogura, K., Takeda, Y., Mizuguchi, J., Yoshimoto
- Organizer
  第37回日本免疫学会総会・学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590418
[Presentation] ナイーブマウスに移入された抗原とAlumでパルスされたDCは抗原特異的Th2細胞をCaspase-1で活性化されるサイトカインの補助無しに誘導する2007
- Author(s)
  今井康友, 安田好文, 林伸樹, 松本真琴, 善本知広, 水谷仁, 中西憲司
- Organizer
  第37回日本免疫学会総会・学術集会
- Place of Presentation
  東京
- Year and Date
  2007-11-22
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] IL-27 suppresses Th2 cell development as well as Th2 cytokines production from polarized Th2 cells;a novel therapeutic way for Th2-mediated allergic inflammation2007
- Author(s)
  Yoshimoto, T., Yoshimoto, T., Yasuda, K., Mizoguchi, J., Nakanishi, K.
- Organizer
  第37回日本免疫学会総会・学術集会
- Place of Presentation
  東京
- Year and Date
  2007-11-21
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] アレルギー性結膜炎に対するIL-33の病因的役割の基礎的解析2007
- Author(s)
  松葉沙織, 善本知広, 安田好文, 池田誠宏, 三村治, 中西憲司
- Organizer
  第57回日本アレルギー学会秋季学術大会
- Place of Presentation
  横浜
- Year and Date
  2007-11-02
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] IL-27 suppresses Th2 cell development as well as Th2 cytokines production from polarized Th2 cells;a novel therapeutic way for Th2-mediated allergic inflammation2007
- Author(s)
  善本知広, 安由公好文, 中西憲司
- Organizer
  第35回日本臨床免疫学会総会
- Place of Presentation
  大阪
- Year and Date
  2007-10-19
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] IL-33は正常マウスに杯細胞を誘導し、Nippostrongylus brasiliensis排虫作用を誘導できる、(ワークショップ)2007
- Author(s)
  安田好文、佐々木由紀、松本真琴、善本知広、中西憲司
- Organizer
  第 37 回日本免疫学会総会・学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] 術後腸管癒着形成の発症機序の解明とその制御法の確立2007
- Author(s)
  善本知広, 中西憲司
- Organizer
  CREST「免疫難病・感染症等の先進医療技術」第4回公開シンポジウム
- Place of Presentation
  東京
- Year and Date
  2007-12-24
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] 花粉で惹起される実験的アレルギー性結膜炎はIL-33で増悪する、(ワークショップ)2007
- Author(s)
  松葉沙織、善本知広、安田好文、池田誠宏、三村治、中西憲司
- Organizer
  第37回日本免疫学会総会・学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] 実験的アレルギー性結膜炎モデルマウスを用いたアレルギー性結膜炎に対するIL-33の病因的役割の解析、(ワークショップ)2007
- Author(s)
  松葉沙織、善本知広、安田好文、池田誠宏、三村治、中西憲司
- Organizer
  第35回日本臨床免疫学会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] ナイーブマウスに移入された抗原とAlumでパルスされたDCはTh2細胞をCaspase-1非依存性に誘導する、(ワークショップ)2007
- Author(s)
  今井康友、安田好文、林伸樹、松本真琴、善本知広、水谷仁、中西憲司
- Organizer
  第35回日本臨床免疫学会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] IL-33のマウス生体内投与はNb排虫作用を有する杯細胞を誘導する2007
- Author(s)
  安田好文, 佐々木由紀, 松本真琴, 善本知広, 中西憲司
- Organizer
  第63回日本寄生虫学会西日本支部大会
- Place of Presentation
  高知
- Year and Date
  2007-10-06
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] Interleukin-27 directly induces the differentiation in hematopoietic stem cells2007
- Author(s)
  T. Yoshimoto, et. al.
- Organizer
  第37回日本免疫学会総会
- Place of Presentation
  東京
- Year and Date
  2007-11-21
- Data Source
  KAKENHI-PROJECT-18659286
[Presentation] IL-18を標的としたTh1型アレルギー性炎症の治療2007
- Author(s)
  善本知広
- Organizer
  第72回日本インターフェロン・サイトカイン学会学術集会
- Place of Presentation
  京都大学、京都
- Year and Date
  2007-07-06
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] NKT cell-driven IFN-γ plays an important role in postoperative adhesion formation2007
- Author(s)
  Kosaka, H., Yoshimoto, T., Fujimoto, J., Nakanishi, K.
- Organizer
  第37回日本免疫学会総会・学術集会
- Place of Presentation
  東京
- Year and Date
  2007-11-20
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] マウス腹腔癒着モデルの確立とIFN-γを中心とし準癒着形成に関わる免疫学的要因の解析2007
- Author(s)
  小坂久, 善本知広, 藤元治朗, 中西憲司
- Organizer
  第72回日本インターフェロン・サイトカイン学会学術集会
- Place of Presentation
  京都大学、京都
- Year and Date
  2007-07-06
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] IL-18を標的としたTh1型アレルギー性炎症の治療、(シンポジウム)2007
- Author(s)
  善本知広
- Organizer
  第72回日本インターフェロン・サイトカイン学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] 花粉で惹起される実験的アレルギー性結膜炎はIL-33で増悪する2007
- Author(s)
  松葉沙織, 善本知広, 安田好文, 池田誠宏, 三村治, 中西憲司
- Organizer
  第37回日本免疫学会総会・学術集会
- Place of Presentation
  東京
- Year and Date
  2007-11-21
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] IL-27 suppresses Th2 cell development as well as Th2 cytokines production from polarized Th2 cells ; a novel therapeutic way for Th2-mediated allergic inflammation.(ワークショップ)2007
- Author(s)
  善本知広、安田公好文、中西憲司
- Organizer
  第35回日本臨床免疫学会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19390121
[Presentation] Contribution of IL-35 to maintaining the testicular immune privilege.
- Author(s)
  Terayama, H., Naito, M., Yoshimoto, T., Hirai, S., Qu, N., Kuramasu, M., Hatayama, N., Kanazawa, T., Suyama, K., Sakabe, K., and Itoh, M.
- Organizer
  第33回日本アンドロロジー学会学術大会
- Place of Presentation
  軽井沢
- Year and Date
  2014-06-12 – 2014-06-13
- Data Source
  KAKENHI-PUBLICLY-25118727
[Presentation] IL-27 exerts potent antitumor activity by promoting the differentiation of hematopoietic stem cells to M1-like antitumor macrophages and their mobilization.
- Author(s)
  Chiba, Y., Furusawa, J., Mizoguchi, I., Xu, M., Mizuguchi, J., and Yoshimoto, T.
- Organizer
  第43回日本免疫学会総会・学術集会
- Place of Presentation
  京都
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PUBLICLY-25118727
[Presentation] Contribution of IL-35 to maintaining the testicular immune privilege.
- Author(s)
  Terayama, H., Naito, M., Yoshimoto, T., Hirai, S., Qu, N., Kuramasu, M., Hatayama, N., Kanazawa, T., Suyama, K., Sakabe, K., and Itoh, M.
- Organizer
  第33回日本アンドロロジー学会学術大会
- Place of Presentation
  軽井沢
- Year and Date
  2014-06-12 – 2014-06-13
- Data Source
  KAKENHI-PROJECT-24370058
[Presentation] PepTivator® OVA-pulsed DCs can induce both OVA specific CD8+ and CD4+ T cells in mouse model.
- Author(s)
  Miki, K., Nagaoka, K., Yoshimoto, T., Kamigaki, T. and Maekawa, R.
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24370058
[Presentation] Regulation of antitumor immune responses through differentiation and mobilization of hematopoietic stem cells by IL-27.
- Author(s)
  Chiba, Y., Mizoguchi, I., Hisada, M., Tsuchida, A., Mizuguchi, J., and Yoshimoto, T.
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26670588
[Presentation] Induction of antigen specific T cells using PepTivator®-pulsed DCs.
- Author(s)
  Takahara, M., Goto, S., Miki, K., Saiwaki, S., Nagaoka, K., Matsushita, H., Kondo, T. Bohnenkamp, H., Yoshimoto, T., Maekawa, R., and Kamigaki, T.
- Organizer
  International Society For Cellular Therapy 20th Annual Meeting 2014
- Place of Presentation
  Paris, France
- Year and Date
  2014-04-23 – 2014-04-26
- Data Source
  KAKENHI-PROJECT-24370058
[Presentation] IL-27 exerts potent antitumor activity by promoting the differentiation of hematopoietic stem cells to M1-like antitumor macrophages and their mobilization.
- Author(s)
  Chiba, Y., Furusawa, J., Mizoguchi, I., Xu, M., Mizuguchi, J., and Yoshimoto, T.
- Organizer
  第43回日本免疫学会総会・学術集会
- Place of Presentation
  京都
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-24370058
[Presentation] Induction of both OVA specific CD4+ and CD8+ T cells by using PepTivator® OVA-pulsed DCs in mouse model.
- Author(s)
  Miki, K., Nagaoka, K., Bohnenkamp, H., Yoshimoto, T., Kamigaki, T. and Maekawa, R.
- Organizer
  American Association for Cancer Research 105th Annual Meeting 2014
- Place of Presentation
  San Diego, California, USA
- Year and Date
  2014-04-05 – 2014-04-09
- Data Source
  KAKENHI-PUBLICLY-25118727
[Presentation] IL-27によるDC前駆細胞の分化・増殖誘導
- Author(s)
  古澤純一、溝口出、水戸部佳奈、樋口要、金子幸太郎、角田廉、水口純一郎、久田将之、粕谷和彦、土田明彦、善本隆之
- Organizer
  第90回東京医科大学・東京薬科大学・免疫アレルギー研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24659595
[Presentation] Intratumoral CD4+ cell depletion sensitizes poorly immunogenic melanomas to immunotherapy with an OX40 agonist
- Author(s)
  Susumu Fujiwara, Hiroshi Nagai, Noriko Shimoura, Shuntaro Oniki, Takayuki Yoshimoto,Chikako Nishigori
- Organizer
  日本研究皮膚科学会　第39回年次学術大会・総会
- Place of Presentation
  大阪
- Year and Date
  2014-12-12 – 2014-12-14
- Data Source
  KAKENHI-PROJECT-25461692
[Presentation] IL-27 promotes the differentiation of hematopoietic stem cells into multipotent myeloid progenitor cells.
- Author(s)
  Furusawa, J., Chiba, Y., Mizoguchi, I., Xu, M., Mizuguchi, J., and Yoshimoto, T.
- Organizer
  第43回日本免疫学会総会・学術集会
- Place of Presentation
  京都
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-26670588
[Presentation] PepTivator® OVA-pulsed DCs can induce both OVA specific CD8+ and CD4+ T cells in mouse model.
- Author(s)
  Miki, K., Nagaoka, K., Yoshimoto, T., Kamigaki, T. and Maekawa, R.
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PUBLICLY-25118727
[Presentation] IL-27 promotes the differentiation of hematopoietic stem cells into multipotent myeloid progenitor cells.
- Author(s)
  Furusawa, J., Chiba, Y., Mizoguchi, I., Xu, M., Mizuguchi, J., and Yoshimoto, T.
- Organizer
  第43回日本免疫学会総会・学術集会
- Place of Presentation
  京都
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-24370058
[Presentation] IL-27 promotes the differentiation of hematopoietic stem cells into multipotent myeloid progenitor cells.
- Author(s)
  Furusawa, J., Chiba, Y., Mizoguchi, I., Xu, M., Mizuguchi, J., and Yoshimoto, T.
- Organizer
  第43回日本免疫学会総会・学術集会
- Place of Presentation
  京都
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PUBLICLY-25118727
[Presentation] IL-27 promotes the differentiation of hematopoietic stem cells into DC progenitor cells.
- Author(s)
  Furusawa, J., Chiba, Y., Mitobe, K., Mizoguchi, I., Mizuguchi, J., and Yoshimoto, T.
- Organizer
  13th International Symposium on Dendritic Cells, DC2014
- Place of Presentation
  Tours, France
- Year and Date
  2014-09-14 – 2014-09-18
- Data Source
  KAKENHI-PUBLICLY-25118727
[Presentation] Induction of antigen specific T cells using PepTivator®-pulsed DCs.
- Author(s)
  Takahara, M., Goto, S., Miki, K., Saiwaki, S., Nagaoka, K., Matsushita, H., Kondo, T. Bohnenkamp, H., Yoshimoto, T., Maekawa, R., and Kamigaki, T.
- Organizer
  International Society For Cellular Therapy 20th Annual Meeting 2014
- Place of Presentation
  Paris, France
- Year and Date
  2014-04-23 – 2014-04-26
- Data Source
  KAKENHI-PUBLICLY-25118727
[Presentation] Induction of both OVA specific CD4+ and CD8+ T cells by using PepTivator® OVA-pulsed DCs in mouse model.
- Author(s)
  Miki, K., Nagaoka, K., Bohnenkamp, H., Yoshimoto, T., Kamigaki, T. and Maekawa, R.
- Organizer
  American Association for Cancer Research 105th Annual Meeting 2014
- Place of Presentation
  San Diego, California, USA
- Year and Date
  2014-04-05 – 2014-04-09
- Data Source
  KAKENHI-PROJECT-24370058
[Presentation] Regulation of antitumor immune responses through differentiation and mobilization of hematopoietic stem cells by IL-27.
- Author(s)
  Chiba, Y., Mizoguchi, I., Hisada, M., Tsuchida, A., Mizuguchi, J., and Yoshimoto, T.
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24370058
[Presentation] Regulation of antitumor immune responses through differentiation and mobilization of hematopoietic stem cells by IL-27.
- Author(s)
  Chiba, Y., Mizoguchi, I., Hisada, M., Tsuchida, A., Mizuguchi, J., and Yoshimoto, T.
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PUBLICLY-25118727
[Presentation] Contribution of IL-35 to maintaining the testicular immune privilege
- Author(s)
  寺山　隼人, 内藤　宗和, 善本　隆之, 平井　宗一, 曲　　　寧, 倉升　三幸, 金沢　輝久, 隅山　香織, 坂部　　貢, 伊藤　正裕
- Organizer
  アンドロロジー学会第33回学術大会および第20回精子形成・精巣毒性研究会
- Place of Presentation
  長野
- Year and Date
  2014-06-12 – 2014-06-13
- Data Source
  KAKENHI-PROJECT-24590243
[Presentation] IL-27 promotes the differentiation of hematopoietic stem cells into DC progenitor cells.
- Author(s)
  Furusawa, J., Chiba, Y., Mitobe, K., Mizoguchi, I., Mizuguchi, J., and Yoshimoto, T.
- Organizer
  13th International Symposium on Dendritic Cells, DC2014
- Place of Presentation
  Tours, France
- Year and Date
  2014-09-14 – 2014-09-18
- Data Source
  KAKENHI-PROJECT-24370058
[Presentation] 癌DCワクチン療法への応用を目指したIL-27を用いたDC前駆細胞の分化・増殖誘導法の開発
- Author(s)
  古澤純一、溝口出、水戸部佳奈、樋口要、金子幸太郎、角田廉、水口純一郎、久田将之、粕谷和彦、土田明彦、善本隆之
- Organizer
  医薬工３大学包括的連携推進シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24659595

1. NARIUCHI Hideo (10012741)

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55. NAITO Munekazu

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56. HIRAI Shuichi

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58. 岩倉洋一郎

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Yoshimoto Takayuki 善本 隆之

YOSHIMOTO Takayuki 善本 隆之

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A novel mechanism whereby EBI3, one of IL-27 cytokine subunits, augments target protein expression under inflammatory conditionsPrincipal InvestigatorOngoing

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Oncofertility視点に基づく若年癌患者の性腺機能不全の漢方治療法の確立Ongoing

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Development of a novel method to generate human iPS cell-derived dendritic cell progenitors and their effectivenessOngoing

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Inhibition of pulmonary fibrosis by mesenchymal stem cells through IL-27 and its clinical applicationOngoing

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Comprehensive study on IL-27, one of the IL-12 family cytokines, aiming at its clinical application for cancer immunotherapyOngoing

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Development of a novel alternative to animal testing for the evaluation of respiratory allergic sensitizing potential of chemicalsOngoing

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Yoshimoto Takayuki 善本隆之

YOSHIMOTO Takayuki 善本隆之