Nagoshi Sumiko 名越澄子

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NAGOSHI Sumiko 名越澄子

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Researcher Number	50306271
Other IDs
Affiliation (Current)	2025: 埼玉医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2003 – 2004: Division of Gastroenterology and Hepatology, Department of Internal Medicine, Saitama Medical School, Associate Professor, 医学部, 助教授 1999 – 2002: 埼玉医科大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Gastroenterology Except Principal Investigator Gastroenterology / Gastroenterology
Keywords	Principal Investigator TNF / Smac(second mitochondria-derived activator of caspase) / IAP(inhibitor of apoptosis protein) / hepatocyte / apoptosis / 肝細胞 / NFκB / アポトーシス / TNF-α / Smac(second mitochondria-derived activator of caspases) … More / TNFα / macrophage / IAP (inhibitor of apoptosis protein) / 肝壊死 / エンドトキシン / D-galactosamine / マクロファージ / IAP(inhibitor of apoptosis) … More Except Principal Investigator Osteopontin / Cytokine / SNP / VEGF / Serine protease / Acetaminophen / Ethanol / HepG2 cells / Apoptosis / セリンプロテアーゼ / アセトアミノフェン / エタノール / HepG2細胞 / アポトーシス / Hepatitis activity / Interferon / Auto immune hepatitis / Chronic hepatitis C / Th1 immune reaction / サイトカイン / オステオポンチン / 肝炎活動性 / インターフェロン / 自己免疫性肝炎 / C型慢性肝炎 / Th1免疫応答 / Transgenic mouse / Stellate cell / Kupffer cell / Sinusoidal endothelial cell / Microcirculatory disturbance / Liver transplantation / プロテオグリカン / ヘパリン / 微小循環 / pericyte / 肝移植後肝不全 / TIE受容体 / Angiopoietin / 肝再生 / osteopontin / Tie受容体 / angiopoiein / 肝星細胞 / 肝類洞内皮細胞 / トランスジェニックマウス / オステオポチン / 星細胞 / クッパー細胞 / 類洞内皮細胞 / 微小循環障害 / 肝移植 Less

Apoptosis via new serine proteases and its intracellular signaling events.
- Principal Investigator
  
  NAKAYAMA Nobuaki
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Saitama Medical School
Genetic Polymorphisms in Promoter Regions of Osteopontin Gene as Host Factors to Determine Th1 Immune Reactions against Hepatitis Virus.
- Principal Investigator
  
  FUJIWARA Kenji
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Saitama Medical School
Activation of Caspases via the Mitochondrial Pathway in Hepatocyte Apoptosis -Roles of IAPs and Smac-Principal Investigator
- Principal Investigator
  
  NAGOSHI Sumiko
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Saitama Medical School
Study on Strategies for Non-Heart Beating Liver
- Principal Investigator
  
  FUJIWARA Kenji
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Saitama Medical School
Mechanisms of Development of Massive Necrosis and Regeneration after Liver Injury Regulated by Activated Sinusoidal MacrophagesPrincipal Investigator
- Principal Investigator
  
  NAGOSHI Sumiko
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Saitama Medical School

All 2005 2004 2003 Other

All Journal Article

[Journal Article] SNPs in the Promoter Region of Osteopontin Gene as a Marker Predicting the Efficacy of Interferon-Based Therapies in Chronic Hepatitis C.2005
- Author(s)
  Naito M, Matsui A, Inao M, Nagoshi S, et al.
- Journal Title
  
  Journal of Gastroenterology (In press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370191
[Journal Article] Plasma Osteopontin Levels in Patients with Fulminant Hepatitis2004
- Author(s)
  Matsui A, Mochida S, Ohno A, Nagoshi S, Hirose T, Fujiwara K
- Journal Title
  
  Hepatology Res 22
  
  Pages: 202-206
- NAID
  10018024812
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370191
[Journal Article] Transgenic mice expressing osteopontin in hepatocytes as a model of autoimmune hepatitis2004
- Author(s)
  Mochida S, Yoshimoto T, Mimura S, Inao M, Matsui A, Ohno A, Koh H, Saitoh E, Nagoshi S, Fujiwara K
- Journal Title
  
  Biochem Biophys Res Commun 317(1)
  
  Pages: 114-120
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590682
[Journal Article] Japanese herbal medicine Inchin-ko-to as a therapeutic drug for liver fibrosis2004
- Author(s)
  Inao M, Mochida S, Matsui A, Eguchi Y, Yulutuz Y, Wang Y, Naiki K, Kakinuma T, Fujimori K, Nagoshi S, Fujiwara K
- Journal Title
  
  J Hepatol 41(4)
  
  Pages: 584-591
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590682
[Journal Article] Massive Liver Necrosis after Provocation of Imbalance between Th1 and Th2 Immune Reactions in Osteopontin Transgenic Mice2004
- Author(s)
  Mimura S, Mochida S, Inao M, Matsui A, Nagoshi S, et al.
- Journal Title
  
  Journal of Gastroenterology 39
  
  Pages: 867-872
- NAID
  10013613344
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370191
[Journal Article] Genetic Polymorphisms in Promoter Region of Osteopontin Gene May be a Marker Reflecting Hepatitis Activity in Chronic Hepatitis C Patients2004
- Author(s)
  Mochida S, Hashimoto M, Matsui A, Naito M, Inao M, Nagoshi S, Egashira T, Mishiro S, Fujiwara K
- Journal Title
  
  Biochem Biophys Res Commun 313
  
  Pages: 1079-1085
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370191
[Journal Article] Imbalance of Th1 and Th2 Immune Reactions May Provoke Massive Liver Necrosis in Osteopontin Transgenic Mice2004
- Author(s)
  Mimura S, Mochida S, Inao M, Matsui A, Nagoshi S, Yamamoto T
- Journal Title
  
  J Gastroenterology 39
  
  Pages: 867-872
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370191
[Journal Article] Transgenic Mice Expressing Osteopontin in Hepatocytes as a Model of Autoimmune Hepatitis2004
- Author(s)
  Mochida S, Yamamoto T, Mimura S, Matsui A, Ohno A, Koh H, Saitoh E, Nagoshi S, Fujiwara K
- Journal Title
  
  Biochem Biophys Res Commun 317
  
  Pages: 114-120
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370191
[Journal Article] Apoptosis in drug-induced liver injuries2003
- Author(s)
  Nakayama N, Matsui A, Nagoshi S, Mochida S, Nakajima J, Koike T, Fujiwara K
- Journal Title
  
  Acta Hepatol Jpn 44 Suppl.1
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590682
[Journal Article] Extrahepatic manifestation in Transgenic Mice of Osteopontin in Hepatocytes : A Clue to Advent of Pathological State in Various Organs of Chronic Hepatitis C Patients
- Author(s)
  Saitoh E, Matsui A, Inao M, Mimura S, Koh H, Ohno A, Nagoshi S, Kayano H, Yoshimoto T, Mochida S, Fujiwara K
- Journal Title
  
  Hepatol Res (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370191
[Journal Article] SNPs in the Promoter Region of Osteopontin Gene as a Marker Predicting the Efficacy of Interferon-Based Therapies in Chronic Hepatitis C
- Author(s)
  Naito M, Matsui A, Inao M, Nagoshi S, Nagano M, Ito N, Egashira T, Hashimoto M, Mishiro S, Mochida S, Fujiwara K
- Journal Title
  
  J Gastroenterol (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370191
[Journal Article] Increased Cytoprotective Function in the Liver of Transgenic Mice Expressing Osteopontin in Hepatocytes
- Author(s)
  Koh H, Matsui A, Mimura S, Inao M, Saitoh E, Ohno A, Nagoshi S, Yoshimoto T, Mochida S, Fujiwara K
- Journal Title
  
  Hepatol Res (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370191

1. MOCHIDA Satoshi (20219968)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
2. INAO Mie (70286037)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
3. FUJIWARA Kenji (80101088)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
4. MATSUI Atsushi (40260484)

# of Collaborated Projects: 3 results

# of Collaborated Products: 12 results
5. YOSHIMOTO Takayuki (80202406)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. NAKAYAMA Nobuaki (40292015)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

Nagoshi Sumiko 名越 澄子

NAGOSHI Sumiko 名越 澄子

Research Projects

Research Products

Co-Researchers

Apoptosis via new serine proteases and its intracellular signaling events.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Genetic Polymorphisms in Promoter Regions of Osteopontin Gene as Host Factors to Determine Th1 Immune Reactions against Hepatitis Virus.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Activation of Caspases via the Mitochondrial Pathway in Hepatocyte Apoptosis -Roles of IAPs and Smac-Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on Strategies for Non-Heart Beating Liver

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanisms of Development of Massive Necrosis and Regeneration after Liver Injury Regulated by Activated Sinusoidal MacrophagesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] SNPs in the Promoter Region of Osteopontin Gene as a Marker Predicting the Efficacy of Interferon-Based Therapies in Chronic Hepatitis C.2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Plasma Osteopontin Levels in Patients with Fulminant Hepatitis2004

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] Transgenic mice expressing osteopontin in hepatocytes as a model of autoimmune hepatitis2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Japanese herbal medicine Inchin-ko-to as a therapeutic drug for liver fibrosis2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Massive Liver Necrosis after Provocation of Imbalance between Th1 and Th2 Immune Reactions in Osteopontin Transgenic Mice2004

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] Genetic Polymorphisms in Promoter Region of Osteopontin Gene May be a Marker Reflecting Hepatitis Activity in Chronic Hepatitis C Patients2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Imbalance of Th1 and Th2 Immune Reactions May Provoke Massive Liver Necrosis in Osteopontin Transgenic Mice2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Transgenic Mice Expressing Osteopontin in Hepatocytes as a Model of Autoimmune Hepatitis2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Apoptosis in drug-induced liver injuries2003

Author(s)

Journal Title

Nagoshi Sumiko 名越澄子

NAGOSHI Sumiko 名越澄子