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NAKAJIMA Takuma
中島 琢磨
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Alternative Names
中島 琢麿 ナカジマ タクマ
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Researcher Number
90256678
Other IDs
External Links
Affiliation (Current)
2023: 了徳寺大学, 健康科学部, 教授
Affiliation (based on the past Project Information)
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2000 – 2003: Graduate School, Tokyo Medical and Dental University, Molecular Cellular Oncology and Microbiology Associate Professor, 大学院・医歯学総合研究科, 助教授
1999: 東京医科歯科大学, 歯学部, 助教授
1998: 東京医科歯科大学, 歯学部, 講師
1996 – 1998: 東京理科大学, 工学部, 助手
1997: 東京理科大学, 基礎工学部・生物工学科, 助手
1993 – 1995: 東京理科大学, 基礎工学部, 助手
1994: 東京理科大学, 基礎工学部・生物工学科, 助手
Review Section/Research Field
Principal Investigator
Cell biology
/
病態科学系歯学(含放射線系歯学)
Except Principal Investigator
Morphological basic dentistry
/
Periodontal dentistry
/
病態科学系歯学(含放射線系歯学)
Keywords
Principal Investigator
アポトーシス / トポイソメラーゼIIα / 細胞周期 / ユビキチン / p53 / E1A / 癌 / アデノウイルスE1A / apoptosis / UbcH7
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More
/ Id / Adenovirus / cell cycle / transcription / interaction / Bacterial pathogen / 癌遺伝子 / アデノウイルス / アデノウィルス E1A / ユビキチン結合酵素 / Ca^<++>依存型 / Mdm2 / UbcH5 / ストレス / E2F / 細胞内蛋白分解 / アデノウイルス E1A / アデノウイルス E1B / 蛋白質分解 / 細胞核 / アデノウイルスE1B / Adenovirus E1A / Adenovirus E1B / topoisomerase IIalpha / Ubiquitin / proteolyses / nuclei / HLH蛋白 / DNA複製 / Tannerella forsyhensis / Actinobacillus actinomycetemcomitans / cytocidal toxin / Cytolethal distending toxin / 殺細胞因子 / 細胞障害 / モノクローナル抗体 / Tannerella forsythensis / cellular toxicity / Cytolethal distending toxin(Cdt) / Cytocidal toxin / monoclonal antibody / ELISA / 歯周病 / 病原因子 / 遺伝子 / ORF / 組換え蛋白質 / 精製 / Tannerella forstyensis / Actinobacillus actinomyctemcomitans / cytocidal toxin(CCT) / cytolethal istending loxin(CDT) / Cell death / cytopathy / monoclonad antibody
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More
Except Principal Investigator
アポトーシス / ERK / Naf1 / EGFR / G2 arrest / 細胞周期 / 歯周病原性細菌 / Bacteroides forsythus / 胎児性癌細胞 / 細胞分化 / N-myc遺伝子 / サイクリンA遺伝子 / 細胞死誘導因子 / Actinobacillus actinomycetemcomitans / ネクローシス / CGH / 口腔癌 / two hybrid system / H-ras / NAF1 / リン酸化 / シグナル伝達 / oral cancer / 歯周炎 / CDT(cytolethal distending toxin) / periodontopathic bacteria / apoptosis / periodontitis / cell cycle / E2F転写因子 / cDNAライブラリィ / ATF転写因子 / 転写制御 / 転写因子E2F / 転写因子ATF / E2F結合タンパク質 / Myc / アデノウイルスE1A / 制がん剤 / Bax / FasL / アポトーシスシグナル / カスパーゼ3様プロテアーゼ / アポトーシス耐性 / LPS / Pim-1キナーゼ / リンパ腫 / ICE / CED-3 family proteases / myc関連遺伝子 / Fas / エンドトキシンLPS / トポイソメラーゼIIα / アポトーシスエンドヌクレアーゼ / 歯周病 / Actinobacillus actinomycetemcomtans / Bacteroides forthysus / 細菌毒素 / CDT / G2チェックポイント / 歯周 / 増幅 / NEF / MEK阻害剤 / 口腔扁平上皮癌 / マップキナーゼ / 酵母 / amplification / 細胞死誘導因子(殺細胞因子) / 殺細胞因子 / cytocidal toxin / CDT (cytolethal distending toxin) / 変異 / microarray / Snt2 / EGG / 増殖シグナル / 生存シグナル / AKT / mutation / microarra / signal trransduction / SNT2 / 細胞死 / 細胞致死因子(CCT) / Tannerella forsythensis / モノクロナール抗体 / 臨床検査 / Tonnerella forsythensis / 細胞死誘導因子(殺細胞因子:CCT) / cytocidal toxin (CCT) / Tannerellaforsythensis / CDT (cytolethal distending toxin).
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Research Projects
(
15
results)
Co-Researchers
(
14
People)
Project Start Year (Newest)
Project Start Year (Oldest)
Aberrant cell growth signaling in oral cancer
Principal Investigator
TSUCHIDA Nobuo
Project Period (FY)
2002 – 2003
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Morphological basic dentistry
Research Institution
Tokyo Medical and Dental University
Analyses for the cytopathic mechanism of cytocidal toxin from periodontpathic bacteria
Principal Investigator
Principal Investigator
NAKAJIMA Takuma
Project Period (FY)
2002 – 2003
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
病態科学系歯学(含放射線系歯学)
Research Institution
Tokyo Medical and Dental University
Isolation of the Cytocidal toxin (CCT) from periodontopathic bacteria and antibody preparation against CCT: with a view to clinical application.
Principal Investigator
ARAKAWA Shinichi
Project Period (FY)
2002 – 2003
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Periodontal dentistry
Research Institution
Tokyo Medical and Dental University
歯周病原性細菌の保有するアポトーシス様細胞死誘導因子の単離・同定
Principal Investigator
土田 信夫
Project Period (FY)
2000 – 2001
Research Category
Grant-in-Aid for Exploratory Research
Research Field
病態科学系歯学(含放射線系歯学)
Research Institution
Tokyo Medical and Dental University
Alterations of ERK gene and the signal transduction pathway in oral squamous cell carcinoma and the roles in the genesis of the cancer
Principal Investigator
TSUCHIDA Nobuo
Project Period (FY)
2000 – 2001
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Morphological basic dentistry
Research Institution
Tokyo Medical and Dental University
Analysis of cell death inducing factors from periodontopathic bacteria.
Principal Investigator
ARAKAWA Shinichi
Project Period (FY)
2000 – 2001
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Periodontal dentistry
Research Institution
Tokyo Medical and DentaJ University
非ストレス負荷ヒト癌細胞におけるCa^<++>依存性ユビキチン化を介する野生型p53の分解とその抑制機構
Principal Investigator
Principal Investigator
中島 琢磨
Project Period (FY)
1999
Research Category
Grant-in-Aid for Scientific Research on Priority Areas (A)
Research Institution
Tokyo Medical and Dental University
アデノウイルスE1A誘導アポトーシスにおけるトポイソメラーゼIIα特異的分解機構
Principal Investigator
Principal Investigator
中島 琢磨
Project Period (FY)
1999
Research Category
Grant-in-Aid for Scientific Research on Priority Areas (A)
Research Institution
Tokyo Medical and Dental University
The function of human HLH-type inhibitor of differentiation, Id-1H and Id-2H that induce abrogation of G1 maturation in mutant p53 expressing cells.
Principal Investigator
Principal Investigator
NAKAJIMA Takuma
Project Period (FY)
1999 – 2000
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Cell biology
Research Institution
Graduate School, Tokyo Medical and Dental University
アデノウィルスE1A誘導アポトーシスにおけるトポイソメラーゼIIα特異的分解機構
Principal Investigator
Principal Investigator
中島 琢磨
Project Period (FY)
1998
Research Category
Grant-in-Aid for Scientific Research on Priority Areas (A)
Research Institution
Tokyo Medical and Dental University
アデノウイルスE1A誘導アポトーシスにおけるトポイソメラーゼIIα特異的分解機構
Principal Investigator
Principal Investigator
中島 琢磨
Project Period (FY)
1997 – 1998
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Tokyo University of Science
アポトーシス機構の解析とその発がん、制がん研究への応用
Principal Investigator
口野 嘉幸
Project Period (FY)
1996 – 1998
Research Category
Grant-in-Aid for Scientific Research on Priority Areas (A)
Research Institution
National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
ヒト胎児性癌細胞の分化誘導におけるN-myc遺伝子の機能と発現調節
Principal Investigator
小田 鈞一郎
Project Period (FY)
1994
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Tokyo University of Science
Molecular Mechanism of Induction and Suppression of Apoptosis by Adenovirus E1A and E1B Gene Products
Principal Investigator
Principal Investigator
NAKAJIMA Takuma
Project Period (FY)
1994 – 1995
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Cell biology
Research Institution
Science University of Tokyo
ヒト胎児性癌細胞の分化誘導におけるN-myc遺伝子の機能と発現制御
Principal Investigator
小田 鈎一郎
Project Period (FY)
1993
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Tokyo University of Science
# of Projects (Dsc)
# of Projects (Asc)
1.
TSUCHIDA Nobuo
(60089951)
# of Collaborated Projects:
8 results
# of Collaborated Products:
0 results
2.
ARAKAWA Shinichi
(20302888)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
3.
小田 鈎一郎
(40012736)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
4.
AMAGASA Teruo
(00014332)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
5.
口野 嘉幸
(60124418)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
6.
田沼 靖一
(10142449)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
7.
三浦 正幸
(50202338)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
8.
藤田 直也
(20280951)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
9.
松沢 昭雄
(50012745)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
10.
ENOMOTO Shouji
(40013940)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
11.
SAKAI. Eiki
(60292976)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
12.
IRITANI Akio
(20292972)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
13.
OMURA Ken
(10334434)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
14.
ISHIKAWA Isao
(10014151)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
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