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hashimoto noriyoshi  橋本 憲佳

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Hashimoto Noriyoshi  橋本 憲佳

HASHIMOTO Noriyoshi  橋本 憲佳

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Researcher Number 50242524
Other IDs
External Links
Affiliation (Current) 2022: 金沢大学, 疾患モデル総合研究センター, 准教授
Affiliation (based on the past Project Information) *help 2018 – 2020: 金沢大学, 学際科学実験センター, 准教授
2013: 金沢大学, 金沢大学, 准教授
2007 – 2013: Kanazawa University, 学際科学実験センター, 准教授
2003 – 2006: Kanazawa Univ., Advanced Science Research Center, Associate Professor, 学際科学実験センター, 助教授
2002: 金沢大学, 医学系研究科, 助手
1995 – 2001: 金沢大学, 医学部, 助手
1992 – 1993: 金沢大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Laboratory animal science / Laboratory animal science / Basic Section 42040:Laboratory animal science-related
Except Principal Investigator
Biological Sciences / Laboratory animal science / Laboratory animal science / Cell biology / Immunology
Keywords
Principal Investigator
実験動物学 / 病態モデル / 血球貪食症候群 / リソソーム病 / 遺伝子改変動物 / 血液疾患 / leaky現象 / V(D)J recombination / 免疫グロブリン / 免疫細胞分化 … More / 血液幹細胞 / SCIDマウス / JVS mice / Systemic carnitine deficiency / Oxygen consumption / Cold-induced thermogenesis / Body-core Temperature / Natural killer activity / Immunoresponse / life span / Legumain / AEP / リソソーム蓄積症 / プロテアーゼ / 疾患モデルマウス / レグマイン / 実験動物 / ゴーシェ細胞 / マクロファージ / 赤血球 / 糖転移酵素遺伝子 / 糖鎖抗原 / 癌特異抗原 / 基幹糖鎖構造 / ガラクトース / ノックアウトマウス / 化学発癌 / Carbohydrate / Knockout mice / Galactosyltransferase / Tumor antigen / Galactose / Chemical carcinogen / Skin tumor / Malignancy / レシピエント / 胚移植 / 近交系 / レシピエントマウス / 偽妊娠マウス … More
Except Principal Investigator
ガラクトース転移酵素 / ノックアウトマウス / 胎生致死 / 糖転移酵素遺伝子 / 遺伝子トラップ / 糖鎖 / セレクチン / 発生制御転写因子 / 原腸陥入 / 中胚葉誘導 / アデノウイルスベクター / IgA腎症 / 骨髄移植 / マウス / xid / beige / scid / IL-1 / 炎症反応 / Knockout mice / Inflammation / 遅延型接触過敏症反応 / 胎盤形成 / 腫瘍抗原 / シアリルLe^x / メチルコラントレン / 腫瘍糖鎖抗原 / 基幹糖鎖構造 / ルイス抗原 / 浸潤・転移 / 初期発生 / 複製開始点認識複合体 / Orc4 / トランスジェニックマウス / 胚性幹細胞 / DNA複製 / 細胞周期 / アスパラギンエンドペプチダーゼ / 抗原プロセッシング / 抗原提示 / 実験的自己免疫性脳脊髄炎 / ミエリン塩基性タンパク質 / 脾臓肥大 / 高IgA血症 / 遺伝子ノックアウトマウス / ネフローゼ / シアル酸生合成 / 行動解析 / 骨随移植 / ミオパチー / 記憶・学習 / 骨髄幹細胞 / ホーミング / nude / 紫外線 / 発がん / 骨髄細胞 / 免疫不全 / 可移植性 / NK細胞 / mouse / immunodeficient / carcinogenesis / UV irradiation / bone marrow / 疾患モデル / 脂肪肝 / 精子 / 心肥大 / トランスポーター / カルニチン / 培養細胞 / 遺伝子量 / mice / animal model / fatty liver / sperm / cardiac hypertrophy / transporter / carnitine / cultured cells / 抗体産生 / 接触過敏症反応 / 関節リウマチ / ストレス応答 / アポトーシス / T細胞フライミング / 細菌誘導性肝炎 / ディファレンシャル・ディスプレイ / エンドトキシンショック / Antibody Production / Contact Hypersensitivity / RheumatoidArthritis / Stress Response / Apoptosis / 皮膚創傷治癒 / ガラクトース糖鎖 / 遅延型過敏症 / コンジェニックマウス / Carbohydrate / Galactosyltransferase / Selectins / Skin wound healing / Embryonic lethal Less
  • Research Projects

    (21 results)
  • Research Products

    (15 results)
  • Co-Researchers

    (14 People)
  •  Development of new albino inbred strain mice for embryo-transfer recipientPrincipal Investigator

    • Principal Investigator
      Hashimoto Noriyoshi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 42040:Laboratory animal science-related
    • Research Institution
      Kanazawa University
  •  Identification of novel homing molecules of hematopoietic stem cells and development of efficient bone marrow transfer methods by modifying carbohydrates

    • Principal Investigator
      ASANO Masahide
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Laboratory animal science
    • Research Institution
      Kanazawa University
  •  Characterization of AEP/Legumain-deficient mice as a new model of lysosome diseasePrincipal Investigator

    • Principal Investigator
      HASHIMOTO Noriyoshi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory animal science
    • Research Institution
      Kanazawa University
  •  Development of mouse models for human diseases caused by impaired glycosylation and analysis of their mechanisms

    • Principal Investigator
      ASANO Masahide
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Laboratory animal science
    • Research Institution
      Kanazawa University
  •  Characterization of AEP/Legumain-deficient mice as a model of hemophagocytic syndrome-like diseasePrincipal Investigator

    • Principal Investigator
      HASHIMOTO Noriyoshi
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory animal science
    • Research Institution
      Kanazawa University
  •  β4-ガラクトース転移酵素-I欠損によるIga腎症発症機構の解析

    • Principal Investigator
      浅野 雅秀
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kanazawa University
  •  自己免疫疾患におけるアスパラギンエンドペプチダーゼによる免疫記憶の調節

    • Principal Investigator
      浅野 雅秀
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kanazawa University
  •  ORC4変異マウスを用いた個体レベルでの細胞周期研究

    • Principal Investigator
      浅野 雅秀
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Cell biology
    • Research Institution
      Kanazawa University
  •  Functional analysis of carbohydrate antigens in chemically induced tumor cells derived from beta-1,4-galactosyltransferase-I knockout micePrincipal Investigator

    • Principal Investigator
      HASHIMOTO Noriyoshi
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory animal science
    • Research Institution
      Kanazawa University
  •  改良遺伝子トラップ法による新規発生制御遺伝子の単離と機能解析

    • Principal Investigator
      浅野 雅秀
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kanazawa University
  •  改良遺伝子トラップ法による新規発生制御遺伝子の単離と機能解析

    • Principal Investigator
      浅野 雅秀
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Biological Sciences
    • Research Institution
      Kanazawa University
  •  糖転移酵素遺伝子欠損マウスを用いた発癌・転移における糖鎖機能の解析

    • Principal Investigator
      浅野 雅秀
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Kanazawa University
  •  Elucidation of individual roles of the galactosyl|ransferase gene family using gene knockout mice

    • Principal Investigator
      ASANO Masahide
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Laboratory animal science
    • Research Institution
      Kanazawa University
  •  ガラクトース転移酵素遺伝子ノックアウトマウスを用いた糖鎖機能の解析

    • Principal Investigator
      浅野 雅秀
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kanazawa University
  •  糖転移酵素遺伝子欠損マウスを用いた発癌・転移における糖鎖機能の解析

    • Principal Investigator
      浅野 雅秀
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Kanazawa University
  •  ガラクトース転移酵素遺伝子ノックアウトマウスを用いた糖鎖機能の解析

    • Principal Investigator
      ASANO Masahide
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kanazawa University
  •  Functional analysis of IL-1 in immune and stress responses using gene knockout mice

    • Principal Investigator
      ASANO Masahide
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Immunology
    • Research Institution
      Kanazawa University
      The University of Tokyo
  •  カルニチン欠乏症(JVS)マウスの病態発生に及ぼす環境ストレスの影響Principal Investigator

    • Principal Investigator
      橋本 憲佳
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Laboratory animal science
    • Research Institution
      Kanazawa University
  •  Evaluation of disease model traits in cultured cells derived from carnitine deficient JVS mice

    • Principal Investigator
      HAYAKAWA Jun-ichiro
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Laboratory animal science
    • Research Institution
      Kanazawa University
  •  免疫担当細胞の分化研究モデルとしてのLeaky SCIDマウスの確立Principal Investigator

    • Principal Investigator
      橋本 憲佳
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Laboratory animal science
    • Research Institution
      Kanazawa University
  •  Characterization of mice carrying multiple mutant genes which cause the different immunological defects.

    • Principal Investigator
      HAYAKAWA Jun-ichiro
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Laboratory animal science
    • Research Institution
      Kanazawa University

All 2018 2014 2011 2009 2007 2006 2005 2004 2003

All Journal Article Presentation

  • [Journal Article] Asparaginyl endopeptidase欠損マウスにおける血球貪食症候群様病態について2011

    • Author(s)
      浅野雅秀, 橋本憲佳
    • Journal Title

      血液内科

      Volume: 63(6) Pages: 634-639

    • URL

      http://www.kahyo.com/item/KS201112-636

    • Data Source
      KAKENHI-PROJECT-21500387
  • [Journal Article] Mice lacking asparaginyl endopeptidase develop disorders resembling hemophagocytic syndrome2009

    • Author(s)
      Chi-Bun Chan, Michiyo Abe, Noriyoshi Hashimoto, Chunhai Hao, Ifor R. Williams, Xia Liu, Shinji Nakao, Akitsugu Yamamoto, Chengyun Zheng, Jan-Inge Henter, Marie Meeths, Magnus Nordenskjold, Shi-Yong Li, Ikuko Hara-Nishimura, Masahide Asano, Keqiang Ye
    • Journal Title

      Proc Natl Acad Sci U S A 106(2)

      Pages: 468-473

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18500325
  • [Journal Article] Mice lacking asparaginyl endopeptidase develop disorders resembling hemophagocytic syndrome.2009

    • Author(s)
      Chan, C. B., Abe, M., Hashimoto, N., et al.
    • Journal Title

      Proceeding of the National Academy of Sciences of the United States of America 106

      Pages: 468-473

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18500325
  • [Journal Article] Development of immunoglobulin A nephropathy-like disease in β-1, 4-galactosyltransferase-I deficient mice2007

    • Author(s)
      Nishie, T., Miyaishi, O., Azuma, H., Kameyama, A., Naruse, C., Hashimoto, N., Yokoyama, H., Narimatsu, H., Wada, T., Asano, M.
    • Journal Title

      Am. J. Pathol. 170

      Pages: 447-459

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19300144
  • [Journal Article] Characterization of serum IgA in beta4GalT I-deficient mice developing IgAN-like disease.2005

    • Author(s)
      Asano M, Nishie T, Miyaishi O, Azuma H, Kameyama A, Naruse C, Hashimoto N, Yokoyama H, Narimatsu H, Wada T.
    • Journal Title

      Nephrology (Carlton) 10 Suppl 6

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15500298
  • [Journal Article] Analysis of human IgA nephropathy-like disease in galactosyltransferase KO mice.2004

    • Author(s)
      Nishie T, Miyaishi O, Naruse C, Hashimoto N, Asano M.
    • Journal Title

      Nephrology (Carlton) 9 Suppl 2

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15500298
  • [Journal Article] Impaired selectin-ligand biosynthesis and reduced inflammatory responses in beta-1,4-galactosyltransferase-I-deficient mice.2003

    • Author(s)
      Asano M, Nakae S, Kotani N, Shirafuji N, Nambu A, Hashimoto N, Kawashima H, Hirose M, Miyasaka M, Takasaki S, Iwakura Y.
    • Journal Title

      Blood 102(5)

      Pages: 1678-1685

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15500298
  • [Presentation] 胚移植レシピエントのための新規アルビノ近交系マウスの開発2018

    • Author(s)
      橋本憲佳,中村由季子,井之上幸範
    • Organizer
      第65回日本実験動物学会総会
    • Data Source
      KAKENHI-PROJECT-18K06026
  • [Presentation] 造血幹細胞の骨髄ホーミングにおける糖鎖の役割2014

    • Author(s)
      橋本憲佳, 田畑佳祐, 高垣聡一郎, 西江敏和, 浅野雅秀
    • Organizer
      第61回日本実験動物学会
    • Place of Presentation
      札幌コンベンションセンター(北海道)
    • Year and Date
      2014-05-15
    • Data Source
      KAKENHI-PROJECT-23650232
  • [Presentation] 造血幹細胞の骨髄ホーミングにおける糖鎖の役割2014

    • Author(s)
      橋本憲佳,田畑佳祐,高垣聡一郎,西江敏和,浅野雅秀
    • Organizer
      第61回日本実験動物学会
    • Place of Presentation
      札幌コンベンションセンター(北海道札幌市)
    • Data Source
      KAKENHI-PROJECT-23650232
  • [Presentation] AEP/Legumain欠損マウス骨髄における血球貪食症候群様病態の解析2011

    • Author(s)
      橋本憲佳
    • Organizer
      第58回日本実験動物学会総会
    • Place of Presentation
      タワーホール船堀(東京)
    • Year and Date
      2011-05-25
    • Data Source
      KAKENHI-PROJECT-21500387
  • [Presentation] AEP/Legumain欠損マウスにおける血球貪食症候群様病態の解析2009

    • Author(s)
      橋本憲佳
    • Organizer
      第56回日本実験動物学会
    • Place of Presentation
      大宮ソニックシティ(埼玉県)
    • Year and Date
      2009-05-15
    • Data Source
      KAKENHI-PROJECT-21500387
  • [Presentation] AEP/Legumain 欠損マウスにおける血球貪食症候群様病態の解析2009

    • Author(s)
      橋本憲佳, 他
    • Organizer
      第56回日本実験動物学会
    • Place of Presentation
      大宮ソニックシティ (埼玉県)
    • Data Source
      KAKENHI-PROJECT-21500387
  • [Presentation] AEP/Legumain欠損マウスにおける血球貪食症候群様病態の解析2007

    • Author(s)
      安陪道代、橋本憲佳、宮石理、中尾眞二、西村いくこ、浅野雅秀
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-18500325
  • [Presentation] Legumain(AEP)遺伝子欠損マウスは血球貪食症候群様の病態を呈する2006

    • Author(s)
      安陪道代, 橋本憲佳, 宮石理, 西村いくこ, 浅野雅秀
    • Organizer
      第53回日本実験動物学会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-18500325
  • 1.  ASANO Masahide (50251450)
    # of Collaborated Projects: 16 results
    # of Collaborated Products: 10 results
  • 2.  SUGIHARA Kazushi (10377418)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  成瀬 智恵 (30372486)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  YOSHIHARA Toru (00401935)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  SUDO Katsuko (50126091)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  IWAKURA Yoichiro (10089120)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  HAYAKAWA Jun-ichiro (50110622)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  ISHIGAKI Yasuto (20232275)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  AKAO Nobuaki (00126559)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  OHNO Shinsuke (70019868)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  NIKAIDO Osamu (60019669)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  KUWAJIMA Masamichi (00205262)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  TAMAI Ikumi (20155237)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  西村 いくこ (00241232)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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