tamai ikumi 玉井郁巳

… Alternative Names

TAMAI Ikumi 玉井郁巳

玉井郁己タマイイクミ

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Researcher Number	20155237
Other IDs
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Affiliation (Current)	2022: 金沢大学, 薬学系, 教授
Affiliation (based on the past Project Information) *help	2008 – 2022: Kanazawa University, 薬学系, 教授 2015: 金沢大学, 医薬保健研究域薬学系, 教授 2007 – 2008: 金沢大学, 自然科学研究科, 教授 2002 – 2007: Tokyo University of Science, Pharmaceutical Sciences, Professor, 薬学部, 教授 2001: Kanazawa University, Pharmaceutical Sciences, Assistant Professor, 薬学部, 助教授 … More 1998 – 2000: Kanazawa University, Graduate School, Associate Professor, 大学院・自然科学研究科, 助教授 1998 – 2000: 金沢大学, 自然科学研究科, 助教授 1999: Kanazawa University, Graduate School, Associate Professor, 自然科学研究所, 助教授 1996 – 1997: Kanazawa University, Pharmaceutics, Assistant Professor, 薬学部, 助教授 1993 – 1995: Kanazawa University, Pharmaceutics, Assistant Professor, 薬学部, 講師 1992: 金沢大学, 薬学部, 助手 1987: FAC. PHARM. SCI., KANAZAWA UNIV. RESEARCH ASSISTANT, 薬学部, 助手 1986: 金沢大学, 薬学部, 教務職員 Less
Review Section/Research Field	Principal Investigator Medical pharmacy / 応用薬理学・医療系薬学 / Physical pharmacy / Biological pharmacy / 医薬分子機能学 / Medium-sized Section 47:Pharmaceutical sciences and related fields / Basic Section 47060:Clinical pharmacy-related Except Principal Investigator 応用薬理学・医療系薬学 / Physical pharmacy / Radiation science … More / Medical pharmacy / Science and Engineering / Digestive surgery / Biological pharmacy / Basic Section 48010:Anatomy-related / Basic Section 52040:Radiological sciences-related / 医薬分子機能学 / Biological Sciences / Applied pharmacology / Physical pharmacy / Laboratory animal science / Digestive surgery / Drug development chemistry / Basic Section 47060:Clinical pharmacy-related Less
Keywords	Principal Investigator トランスポーター / OATP / 薬物動態 / OCTN / 消化管吸収 / 薬物間相互作用 / transporter / ドラッグデリバリー / 血液脳関門 / 胆汁中排泄 … More / 消化管 / 輸送体 / マイクロRNA / 食品 / ナノ粒子 / アフリカツメガエル卵母細胞 / 担体輸送 / 薬物輸送 / 担体介在輸送 / 肝取り込み / 有機アニオン / 肝毒性 / 肝臓 / 有機アニオントランスポーター / 尿酸 / 高尿酸血症 / 再吸収 / 可視化 / MRP2 / 肝細胞 / BCRP / 薬物相互作用 / 膜輸送 / カルニチン / 有機カチオン / drugs / carnitine / 毒性 / Transporter / 栄養素 / 消化管機能 / 薬食相互作用 / OATP2B1 / 発現調節 / 外来性遺伝子発現 / β-ラクタム抗生物質 / ジペプチドトランスポーター / ペプチド輸送 / モノカルボン酸輸送 / 遺伝子クローニング / モノクルボン酸 / 血球 / 分化 / 増殖 / アミノ酸 / アルギニン / CAT1 / 薬物動態学 / 動物種差 / 体内動態 / 種差 / βラクタム抗生物質 / ナフシリン / 腎臓 / 尿酸値変動 / URAT1 / URATv1 / 発現系 / 尿酸排泄促進薬 / ベンズブロマロン / ロサルタン / OAT / in vitro発現系 / 薬物毒性 / BSEP / 胆汁うっ滞 / オルガネラ / 副作用 / 胆汁排泄 / 薬物誘導性肝障害 / ドネペジル / シロスタゾール / Local DDI / Local-DDI / 心毒性 / ドラッグデリバリー / P-糖蛋白 / モノカルボン酸 / β-アミノ酸 / トランスポート / 培養細胞 / 脳毛細血管内皮細胞 / Blood-brain barrier / carrier-mediated transport / drug delivery / drug disposition / P-glycoprotein / monocarboxylic acid / beta-amino acid / カルニチン欠乏症 / 腎血吸収 / 尿細管分泌 / 薬物 / 能動分泌 / 遺伝疾患 / organic cations / carnitine deficiency / renal reabsorption / avtive secretion / 脳 / 中枢解毒 / 脳毛細血管内皮 / アストロサイト / 排出輸送 / 共培養 / 内皮細胞 / 密着結合 / 中枢デリバリー / 脳解毒 / P-糖タンパク / 脳毛細血管 / blood-brain barrier / brain capillary indothelial cell / carnitine transporter / amino acid transporter / monocarboxylic acid transporter / astrocyte / coculture / 基質選択性 / 腎 / 肝 / substrate specificity / organic anion / organic cation / liver / 輸送 / 遺伝子多型 / 核内受容体 / 遺伝子発現調節 / 発現調節機構 / 尿中排泄 / 有機カチオントランスポーター / Membrane transport / Toxicity / Drug interaction / Genetic polymorphism / Nuclear receptor / Regulation of gene expression / 乳癌 / ホルモン療法 / エストロン硫酸 / 細胞増殖 / 抱合型エストロゲン / MCF7細胞 / ホルモン / 生理活性 / 乳がん / エストロゲン / エストロン / MCF7 / Breast Cancer / Hormone therapy / Estrone sulfate / Cell growth / Conjugatedestrogen / MCF7 cells / 食品ナノ粒子 / 食品高分子 / 発現変動 / カテキン / 相互作用 / 食品成分 / 薬学 / 嗜好飲料 / 個体間変動 / 筋肉 / 筋毒性 / 予測マーカー / 食品作用 / 食品由来微粒子 / 食品由来マイクロベシクル / 食品由来高分子成分 / リンゴ / ASBT / NDFIP1 / CD38 / 痛風 / 受容体 / センサー / 脂質代謝 / 臓器間相互作用 … More Except Principal Investigator トランスポーター / 血液脳関門 / JTS-1 / transporter / P-糖蛋白質 / 有機カチオン / オリゴペプチド / 消化管吸収 / ドラッグデリバリー / Drug Delivery System / 遺伝子発現 / 脳毛細血管内皮細胞 / カルニチン / 生体防御 / β-ラクタム抗生物質 / P-糖タンパク質 / 抗がん剤 / アデノウイルス / 薬物体内動態 / 定量PCR / アニオン性PEG誘導体 / DNAマイクロアレイ / 抗癌剤耐性遺伝子 / ヒト培養細胞 / 腫瘍診断薬 / 設計戦略 / 遺伝子発現解析 / 分子イメージング / モノカルボン酸 / P-glycoprotein / drug delivery / 多剤耐性 / ビンクリスチン / ゼノバイオティクス / 有機アニオン / ペプチド / 組織分布 / ドラックデリバリー / アデノウィルス / ポリエチレンイミン / 分子標的治療 / DDS / 糖尿病 / 消化管 / アミノ酸トランスポータ / 化学療法 / 薬物動態学 / 経口吸収 / 輸送体 / がん / 機能性分子発現系 / 薬物トランスポータ / ポストＦＤＧ製剤 / Caco-2 / 培養細胞 / Blood-brain barrier / blood-brain barrier / doxorubicin / secondary active transport / monocarboxylic acid transporter / peptides / adsorptive-mediated endocytosis / 全身性カルニチン欠乏症 / トランスポータ / monocarboxylic acid / quantitative PCR / 遺伝子治療 / 画像診断薬 / 核医学 / SPECT / アフリカツメガエル / 卵母細胞 / ウリジン / 輸送担体 / 組織標的化 / 小腸吸収 / 薬物分子設計 / P‐糖蛋白質 / サイクロスポリンA / 脳虚血 / 能動排出 / ノックアウトマウス / 異物排出トランスポーター / 薬物相互作用 / テトラエチルアンモニウム / 尿細管再吸収 / 尿細管分泌 / シンクロナイゼーション / 遺伝子クローニン / ニューキノロン抗菌薬 / クローニング / 突然変異 / 遺伝子欠損動物 / green fluoresscet protein / 蛍光顕微鏡 / ゼノバイオティックス / 小腸上皮細胞 / 異物排泄 / 薬物代謝酵素 / 消化菅分泌 / 発現変動 / 体内動態 / アンチセンス / ノックアウト / CMVプロモーター / オセルタミビル / 相互作用 / PEPT1 / 高分子複合体 / 配糖体 / ヘキソーストランスポーター / インクレチン / デンドリマー / SGLT1 / GLP-1 / 糖鎖 / 機能性分子発現解析 / ポストFDG / PET製剤 / 腫瘍集積性 / アミノレブリン酸 / プロトポルフィリン / フェロキラターゼ / 光力学療法 / プロトポルフォリン / 薬物排泄 / 光力学診断 / 蛍光診断 / 薬学 / 徐放性製剤 / 代謝酵素 / 薬物間相互作用 / 生体分子 / 薬物動態・代謝学 / 前立腺癌 / ホルモン / 去勢抵抗性 / 前立腺がん / OATP / 幹細胞 / 白血病 / ポストＦＤＧ / 細胞集積機序 / 腫瘍細胞集積機序 / 尿酸輸送体 / 尿酸 / インスリン / 解糖系 / 精神神経疾患 / 治療効果 / 個体差要因 / 薬物代謝酵素活性 / 個別化薬物療法 / 放射性画像診断薬 / 個体差 / 治療効果判定 / 分子標的 / 放射性診断薬 / 神経化学的評価 / 有機アニオン輸送ポリペプチド / エストロゲン前駆体 / 乳がん / エストロゲン受容体 / 分子生物学的研究 / プロトン共輸送 / 内皮細胞 / P糖蛋白質 / Monocarboxylic acid / Proton cotransport / Gene expression / beta-Lactam antibiotics / Brain caillary endothelial cells / P-Glycoprotein / β-alanine / absorptive-mediated endocytosis / blood-brain-barrier / P-glycoprptein / drug efflux pump / amino acids / blood-brain barrer / doxonibicin / taurine / monocarboxylic acid transpoter / MCT1 / beta-alanine / マウス / 疾患モデル / 脂肪肝 / 精子 / 心肥大 / 遺伝子量 / mice / animal model / fatty liver / sperm / cardiac hypertrophy / carnitine / cultured cells / 薬物動態 / H^+-輸送担体 / HCO3^--逆輸送担体 / H^+-逆輸送担体 / カルニチンNa^+-輸送担体 / 全身性カルチニン欠乏症 / JVSマウス / pharmacokinetics / organic cation / Carnitine / 遺伝子発現系 / エンドサイトーシス / H^+輸送担体 / HCO3^-交換輸送担体 / valacyclovir / L-dopa-L-phenylalanine / ペプチド化プロドラッグ / intestinal absorption / peptide / gene expression / drug delivery endocytosis / アデノウイルスベクター / SNP / ポリロタキサン / 腎排泄 / H1アンタゴニスト / 輸送駆動力 / absorption / drug disposition / systemic carintine deficiency / adenovirus vector / single nucleotide polymorphism / グリシルザルコシン / 腫瘍 / ベスタチン / グリシルサルコシン / ヌードマウス / トラックデリバリー / oligopeptide / anti-cancer reagent / bestatine / tumor / nude mouse / 分子標的冶療 / Transferrin結合PEG-リポソーム / ドラッグデリバリーシステム / インテリジェント化 / トランスフェリン-PEG-リポソーム / Oxaliplatin / Qplex / 癌抑制遺伝子 / Transporter / Anticancer resistant gene / DNA Microarray / Molecular targeting therapy / Anionic Polyethylene glycol / Transfferin binding PEG-Liposome / JTS-1,4DDS / ターゲティング / DNAマクロアレイ / JTS-1、4 DDS / Polyethyleneimine / anionic PEG complex / Gene Therapy / Multidrug resistant gene / Targeting / 加齢変動 / ジペプチド輸送系 / 有機アニオン輸送系 / 血清蛋白結合 / 抗菌薬 / セファゾリン / ジプペチド輸送系 / 抗菌性抗生物質 / Tissue distribution / Peptide transport system / Organic anion transport system / Serum protein binding / Antimicrobial agent / <beta>-lactam antibiotics / cefazolin / フラボノイド / TEDB / 多剤耐性がん / Collateral sensitivity / 多剤耐性がん細胞 / フラボノイド誘導体 / 異所性P-糖タンパク / 有糸分裂阻害効果 / 機能性分子安定発現系 / ポストFDG 製剤 / アミノ酸トランスポーター / 薬物トランスポーター / 癌関連トランスポーター / 開発戦略 / 個別化治療 / 個別化医療 / 小動物イメージング / 精子形成 / 細胞接着分子 / ミトコンドリア / 鞭毛形成 / 免疫沈降 / 質量分析 / 細胞小器官 / 形態形成 / 細胞小器官の配置 / 水分 / モデリング＆シミュレーション / SGLT / セラノスティクス / PET / がん細胞 / 治療標的 / レドックス制御 / ダウン症候群 / 精巣 / 精子形成障害 / 男性不妊症 / トリソミー / 原因遺伝子 Less

細胞内レドックス制御を司るがん幹細胞治療の標的トランスポーター画像診断薬の開発
- Principal Investigator
  
  川井恵一
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Kanazawa University
血清尿酸値を感受する尿酸センサーの同定と生理作用Principal Investigator
- Principal Investigator
  
  玉井郁巳
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Kanazawa University
ナトリウム共役能動輸送型糖輸送体を標的としたセラノスティクス薬剤の開発
- Principal Investigator
  
  小林正和
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Kanazawa University
A search of novel genes involved in spermatogenesis failure of Down syndrome model mice
- Principal Investigator
  
  若山友彦
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48010:Anatomy-related
- Research Institution
  Kumamoto University
Quantitative Prediction of Oral Drug Absorption by Kinetically Analyzing Gastrointestinal Water Dynamics
- Principal Investigator
  
  白坂善之
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Kanazawa University
Regulation of intestinal function via microRNA from fruit-derived microvesiclesPrincipal Investigator
- Principal Investigator
  
  Tamai Ikumi
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  Kanazawa University
Molecular mechanism of organelle positioning and flagellar formation regulated by cell adhesion molecule
- Principal Investigator
  
  Wakayama Tomohiko
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48010:Anatomy-related
- Research Institution
  Kumamoto University
Drug-food interaction on transportersPrincipal Investigator
- Principal Investigator
  
  TAMAI IKUMI
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kanazawa University
Micro RNA-mediated expressional regulation of transportersPrincipal Investigator
- Principal Investigator
  
  Ikumi Tamai
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Medical pharmacy
- Research Institution
  Kanazawa University
Development strategy of tumor diagnostic agent by system upregulated functional biomolecule based on expression analysis of tumor associated transporter
- Principal Investigator
  
  KAWAI Keiichi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Kanazawa University
Development of high accuracy multidrug resistance prediction method using SPECT imaging for individualized anticancer therapy
- Principal Investigator
  
  KOBAYASHI Masato
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Kanazawa University
Local drug-drug interaction of donepezil with cilostazol at BCRP transporterPrincipal Investigator
- Principal Investigator
  
  Tamai Ikumi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Medical pharmacy
- Research Institution
  Kanazawa University
Development of a molecular targeted radiolabeled diagnostic agent useful for personalized drug therapy of psychoneurotic diseases
- Principal Investigator
  
  KAWAI Keiichi
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Kanazawa University
Impact of transporters for uptake of estrogen precursors on progression of breast cancer cells
- Principal Investigator
  
  JUN Matsumoto
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Biological pharmacy
- Research Institution
  International University of Health and Welfare
Chemical biology of MDR cancer selective cytotoxicity using natural product derivatives
- Principal Investigator
  
  Goto Kyoko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Drug development chemistry
- Research Institution
  Kanazawa University
The design strategy for tumor diagnostic agents utilizing the functional biomolecule expression system based on gene expression analysis of tumor cells
- Principal Investigator
  
  KAWAI Keiichi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Kanazawa University
Exploration of association mechanism between hyperuricemia and insulin resistance
- Principal Investigator
  
  KOMORI Hisakazu
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Medical pharmacy
- Research Institution
  Kanazawa University
Regional Difference in the Effect of Influx/Efflux Transporters and Metabolic Enzymes on Intestinal Drug Absorption
- Principal Investigator
  
  SHIRASAKA Yoshiyuki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kanazawa University
New rational for chemotherapy targeting transporters expressed in cancer stem cells
- Principal Investigator
  
  NAKANISHI Takeo
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kanazawa University
Application of Sandwich-cultured hepatocytes for analysis of drug-drug interaction on bile canalicular transportersPrincipal Investigator
- Principal Investigator
  
  TAMAI Ikumi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Medical pharmacy
- Research Institution
  Kanazawa University
Clarification and evaluation of regulation mechanism of uric acidPrincipal Investigator
- Principal Investigator
  
  TAMAI Ikumi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kanazawa University
Manipulation of gastrointestinal functions by polymeric conjugates bearing glucosides, oral anti-diabetic drugs
- Principal Investigator
  
  SAKUMA Shinji
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Setsunan University
細胞内オルガネラ膜トランスポーター活性の定量的可視化による薬物の細胞毒性評価Principal Investigator
- Principal Investigator
  
  玉井郁巳
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Medical pharmacy
- Research Institution
  Kanazawa University
The probe design strategy of post-FDG tumor diagnostic agents based on the functional biomolecule expression analysis of human cultured cells
- Principal Investigator
  
  KAWAI Keiichi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Kanazawa University
Evaluation of molecular mechanisms of tumor-specific protoporphyr in accumulation induced by 5-aminolevulinic acid
- Principal Investigator
  
  NAKANISHI Takeo
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Biological pharmacy
- Research Institution
  Kanazawa University
Species difference in hepatic disposition of organic anionsPrincipal Investigator
- Principal Investigator
  
  TAMAI Ikumi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kanazawa University
  Tokyo University of Science
The mechanism and its inter-individual variability of the Blood-Brain Barrier penetration of anti-influenza drug, oseltamivir
- Principal Investigator
  
  MORIMOTO Kaori
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Takasaki University of Health and Welfare
トランスポーター発現プロファイルに基づく細胞分化・増殖制御手法Principal Investigator
- Principal Investigator
  
  玉井郁巳
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Medical pharmacy
- Research Institution
  Tokyo University of Science
Establishment of Novel Anti-Hormone Therapy of Breast Cancer based on the Inhibition of Uptake Transporter of Conjugated Estrogen by Cancer Cells.Principal Investigator
- Principal Investigator
  
  TAMAI Ikumi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  TOKYO UNIVERSITY OF SCIENCE
トランスポーターを応用したインテリジェントDDSによる癌分子標的治療
- Principal Investigator
  
  YANAGIE Hironobu
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  The University of Tokyo
Drug Toxicity Induced by Alteration of Transporter ActivityPrincipal Investigator
- Principal Investigator
  
  TAMAI Ikumi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  TOKYO UNIVERSITY OF SCIENCE
Development of Gene Therapy with Nanotechnology derived Intelligent Drug Deliver Systems
- Principal Investigator
  
  YANAGIE Hironobu
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  The University of Tokyo
アンチセンス発現アデノウイルスを用いたトランスポーターの薬物体内動態制御機能評価
- Principal Investigator
  
  辻彰
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kanazawa University
ゼノバイオティックスの取り込みと排出輸送がシンクロナイズした生体防御機構
- Principal Investigator
  
  辻彰
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Kanazawa University
STUDIES FOR THE MECHANISM OF MULTIPLICITY IN SUBSTRATE SPECIFICITY OF TRANSPORTERS.Principal Investigator
- Principal Investigator
  
  TAMAI Ikumi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  TOKYO UNIVERSITY OF SCIENCE
  Kanazawa University
Molecular Targeting Therapy with Intelligent Drug Delivery System using Transporter
- Principal Investigator
  
  YANAGIE Hironobu, 吉崎巖
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  THE UNIVERSITY OF TOKYO
トランスポーター発現アデノウイルスベクターを用いたペプチド様抗がん剤の脳腫瘍送達
- Principal Investigator
  
  崔吉道
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
Drug Delivery based on Multiplicity of Various Membrane Transporters
- Principal Investigator
  
  TSUJI Akira
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kanazawa University
Delivery of peptide-mimetic drugs to tumors utilizing oligopeptide transporters
- Principal Investigator
  
  TSUJI Akira
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  KANAZAWA UNIVERSITY
Evaluation of the blood-brain barrier based on the functional analysis of transporters using newly developed techniques.Principal Investigator
- Principal Investigator
  
  TAMAI Ikumi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  KANAZAWA UNIVERSITY
ゼノバイオティックス取り込み・排出輸送と化学変換がシンクロナイズした生体防御機構
- Principal Investigator
  
  辻彰
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Science and Engineering
- Research Institution
  Kanazawa University
薬物トランスポーター群の分子認識・輸送の多様性の解明とその創薬への応用
- Principal Investigator
  
  辻彰
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  医薬分子機能学
- Research Institution
  Kanazawa University
Functional characterization and relevance of carnitine transporter OCTN2 to secondary carnitine deficiency.Principal Investigator
- Principal Investigator
  
  TAMAI Ikumi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  医薬分子機能学
- Research Institution
  KANAZAWA UNIVERSITY
薬物相互作用による血液脳関門輸送系・排出ポンプ機能修飾と薬物中枢移行変動
- Principal Investigator
  
  辻彰
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kanazawa University
Drug deliver by utilization of tissue specific transportes.
- Principal Investigator
  
  TSUJI Akira
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  KANAZAWA UNIVERSITY
Intestinal absorption of drugs mediated by transporters in intestinal epithelial cells
- Principal Investigator
  
  TSUJI Akira
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  KANAZAWA UNIVERSITY
Molecular mechanism of blood-brain barrier transport of drugs.Principal Investigator
- Principal Investigator
  
  TAMAI Ikumi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  KANAZAWA UNIVERSITY
モノカルボン酸輸送系の組織特異的機能発現とドラッグテリバリーへの応用Principal Investigator
- Principal Investigator
  
  玉井郁巳
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kanazawa University
Evaluation of disease model traits in cultured cells derived from carnitine deficient JVS mice
- Principal Investigator
  
  HAYAKAWA Jun-ichiro
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Kanazawa University
外来性遺伝子発現系を用いた小腸上皮薬物担体輸送機構の解明Principal Investigator
- Principal Investigator
  
  玉井郁己
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kanazawa University
Blood-brain barrier functioning as dynamic interface and drug delivery to the brain
- Principal Investigator
  
  TSUJI Akira
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kanazawa University
P‐糖蛋白質の血液脳関門機能解明と薬物脳移行制御法の開発
- Principal Investigator
  
  辻彰
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kanazawa University
小腸上皮薬物担体輸送の分子機構論的解明と薬物の経口デリバリーへの応用Principal Investigator
- Principal Investigator
  
  玉井郁巳
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kanazawa University
アフリカツメガエル卵母細胞発現系を用いた薬物輸送機構の分子論的解析
- Principal Investigator
  
  TERASAKI Tetsuya
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kanazawa University
Clarification of transcellular transport mechanism of drugs utilizing tissue cultured cell systems
- Principal Investigator
  
  TSUJI Akira
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kanazawa University
Quantitative analysis of factors determining age-related change in tissue distribution of animicrobial agents
- Principal Investigator
  
  TSUJI Akira
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  KANAZAWA UNIVERSITY

[Book] 臨床薬学テキストシリーズ、循環器／腎・泌尿器／代謝／内分泌、2020
- Author(s)
  玉井郁巳
- Total Pages
  381
- Publisher
  中山書店
- ISBN
- Data Source
  KAKENHI-PROJECT-16H05111
[Book] 月刊薬事2016
- Author(s)
  玉井郁巳
- Total Pages
  218
- Publisher
  薬事日報社
- Data Source
  KAKENHI-PROJECT-16H05111
[Book] 医療薬学VI薬の体内運命2016
- Author(s)
  玉井郁巳
- Total Pages
  195
- Publisher
  東京化学同人
- Data Source
  KAKENHI-PROJECT-16H05111
[Book] 薬物の消化管吸収予測研究最前線2010
- Author(s)
  玉井郁巳, ら共著
- Total Pages
  130
- Publisher
  株式会社メディカルドゥ
- Data Source
  KAKENHI-PROJECT-21659038
[Book] 薬物代謝学・医療薬学・医薬品開発の基礎として、第3版2010
- Author(s)
  玉井郁巳, ら共著
- Total Pages
  250
- Publisher
  東京化学同人
- Data Source
  KAKENHI-PROJECT-21659038
[Book] 細胞の構造とオルガネラ2010
- Author(s)
  玉井郁巳, ら共著
- Total Pages
  271
- Publisher
  廣川書店
- Data Source
  KAKENHI-PROJECT-21659038
[Book] 薬物の消化管吸収予測研究最前線2010
- Author(s)
  玉井郁巳, ら共著
- Total Pages
  130
- Publisher
  株式会社メディカルドゥ
- Data Source
  KAKENHI-PROJECT-21390044
[Book] 薬物代謝学・医療薬学・医薬品開発の基礎として、第3版2010
- Author(s)
  玉井郁巳, ら共著
- Total Pages
  250
- Publisher
  東京化学同人
- Data Source
  KAKENHI-PROJECT-21390044
[Book] 細胞の構造とオルガネラ2010
- Author(s)
  玉井郁巳, ら共著
- Total Pages
  271
- Publisher
  廣川書店
- Data Source
  KAKENHI-PROJECT-21390044
[Book] 薬物トランスポーター活用ライブラリー2009
- Author(s)
  玉井郁巳, ら共著
- Total Pages
  246
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-21659038
[Book] 薬と疾病IB。薬の効くプロセス(2)薬剤2009
- Author(s)
  玉井郁巳
- Total Pages
  192
- Publisher
  東京化学同人
- Data Source
  KAKENHI-PROJECT-21390044
[Book] 薬と疾病IB。薬の効くプロセス(2)薬剤2009
- Author(s)
  玉井郁巳, ら共著
- Total Pages
  192
- Publisher
  東京化学同人
- Data Source
  KAKENHI-PROJECT-21659038
[Book] 薬と疾病IB。薬の効くプロセス (2) 薬剤2009
- Author(s)
  玉井郁巳, ら共著
- Total Pages
  192
- Publisher
  東京化学同人
- Data Source
  KAKENHI-PROJECT-21390044
[Book] 臨床薬物動態学2009
- Author(s)
  玉井郁巳
- Total Pages
  415
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-21390044
[Book] 臨床薬物動態学2009
- Author(s)
  玉井郁巳, ら共著
- Total Pages
  415
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-21390044
[Book] 薬物トランスポーター活用ライブラリー2009
- Author(s)
  玉井郁巳, ら共著
- Total Pages
  246
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-21390044
[Book] 最新トランスポーター研究 : 消化管と肝臓2009
- Author(s)
  玉井郁巳
- Total Pages
  259
- Publisher
  株式会社メディカルドゥ
- Data Source
  KAKENHI-PROJECT-19390046
[Book] 臨床薬物動態学2009
- Author(s)
  玉井郁巳, ら共著
- Total Pages
  415
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-21659038
[Book] 薬物トランスポーター活用ライブラリー2009
- Author(s)
  玉井郁巳
- Total Pages
  246
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-21390044
[Book] 創薬支援研究の展望2008
- Author(s)
  荻原琢男、森本かおり、玉井郁巳
- Publisher
  株式会社シーエムシー出版
- Data Source
  KAKENHI-PROJECT-19599023
[Book] 最新創薬学2007 -薬物動態学特性の解析は創薬のキーワード-2007
- Author(s)
  色川正憲, 玉井郁巳
- Total Pages
  308
- Publisher
  株式会社メディカルドゥ
- Data Source
  KAKENHI-PROJECT-17390046
[Book] 最新創薬学2007 -薬物動態学特性の解析は創薬のキーワード-2007
- Author(s)
  色川正憲, 玉井郁巳
- Total Pages
  303
- Publisher
  株式会社メディカルドウ
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390046
[Journal Article] Multiple Transport Mechanisms Involved in the Intestinal Absorption of Metformin: Impact on the Nonlinear Absorption Kinetics2022
- Author(s)
  Yoshiyuki Shirasaka, Maria Seki, Marie Hatakeyama, Yuko Kurokawa, Hiroki Uchiyama, Miyuki Takemura, YugoYasugi, Hisanao Kishimoto, Ikumi Tamai, Joanne Wang, Katsuhisa Inoue
- Journal Title
  
  Journal of Pharmaceutical Sciences
  
  Volume: 111 Pages: 1531-1541
- DOI
  10.1016/j.xphs.2022.01.008
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21J21599, KAKENHI-PROJECT-20K07165
[Journal Article] 食品成分と薬物の相互作用2022
- Author(s)
  玉井郁巳、朱秋楠
- Journal Title
  
  実験医学増刊
  
  Volume: 40-7 Pages: 70-77
- Data Source
  KAKENHI-PROJECT-20K21474
[Journal Article] Model Analysis of the Apparent Saturation Kinetics of Purine Nucleobase Uptake in Cells co-Expressing Transporter and Metabolic Enzyme2021
- Author(s)
  Suzuki Satoru、Inoue Katsuhisa、Tamai Ikumi、Shirasaka Yoshiyuki
- Journal Title
  
  Pharmaceutical Research
  
  Volume: 38 Pages: 1585-1592
- DOI
  10.1007/s11095-021-03086-w
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21J12535, KAKENHI-PROJECT-20K07165
[Journal Article] A novel fluorescence-based method to evaluate ileal apical sodium-dependent bile acid transporter ASBT.2021
- Author(s)
  Zhu Q, Komori H, Imamura R, Tamai I.
- Journal Title
  
  Journal of Pharmaceutical Sciences
  
  Volume: 110 Pages: 1392-1400
- DOI
  10.1016/j.xphs.2020.11.030
- Data Source
  KAKENHI-PROJECT-20K21474
[Journal Article] MicroRNAs in apple-derived nanoparticles modulate intestinal expression of OATP2B1/SLCO2B1 in humans.2021
- Author(s)
  Komori H, Fujita D, Shirasaki Y, Zhu Q, Iwamoto Y, Nakanishi T, Nakajima N, Tamai I.
- Journal Title
  
  Drug Meatbolism and Disposition
  
  Volume: 49 Pages: 803-809
- DOI
  10.1124/dmd.121.000380
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21474
[Journal Article] Biological distribution of orally administrated [123I]MIBG for estimation of gastrointestinal tract absorption2021
- Author(s)
  Kobayashi M, Mizutani A, Muranaka Y, Nishi K, Komori H, Nishii R, Shikano N, Nakanishi T, Tamai I, Kawai K
- Journal Title
  
  Pharmaceutics
  
  Volume: 14 Pages: 61-61
- DOI
  10.3390/pharmaceutics14010061
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02865
[Journal Article] Uptake Pathway of Apple-derived Nanoparticle by Intestinal Cells to Deliver its Cargo2021
- Author(s)
  Arai M, Komori H, Fujita D, Tamai I
- Journal Title
  
  Pharmaceutical Research
  
  Volume: 38 Pages: 523-530
- DOI
  10.1007/s11095-021-03018-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21474, KAKENHI-PROJECT-19K16408
[Journal Article] 尿酸再吸収トランスポーターURAT1＆GLUT92021
- Author(s)
  玉井郁巳
- Journal Title
  
  ファルマシア 57:897-901, 2021.
  
  Volume: 57 Pages: 897-901
- NAID
  130008095686
- Data Source
  KAKENHI-PROJECT-21H02641
[Journal Article] Influence of osmolality on gastrointestinal fluid volume and drug absorption: potential impact on oral salt supplementation2021
- Author(s)
  Miyuki Takemura, Yuki Tanaka, Katsuhisa Inoue, Ikumi Tamai and Yoshiyuki Shirasaka
- Journal Title
  
  Journal of Pharmaceutical Health Care and Sciences
  
  Volume: 7:29 Pages: 29-29
- DOI
  10.1186/s40780-021-00212-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21J21599, KAKENHI-PROJECT-20K07165
[Journal Article] Inhibition of the Hepatic Uptake of (99m)Tc-Tetrofosmin Using an Organic Cation Transporter Blocker2021
- Author(s)
  Nishi K, Kobayashi M, Kikuchi M, Mizutani A, Muranaka Y, Tamai I, Kawai K, Kudo T.
- Journal Title
  
  Pharmaceutics
  
  Volume: 13 Pages: 1073-1073
- DOI
  10.3390/pharmaceutics13071073
- NAID
  120007172275
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02865, KAKENHI-PROJECT-20K08053
[Journal Article] CD38 activation by monosodium urate crystals contributes to inflammatory response in macrophages.2021
- Author(s)
  Wen S, Arakawa H, Tamai I
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 581 Pages: 6-11
- DOI
  10.1016/j.bbrc.2021.10.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-20H05745, KAKENHI-PROJECT-21H02641
[Journal Article] 3CL Protease Inhibitors with an Electrophilic Arylketone Moiety as Anti-SARS-CoV-2 Agents2021
- Author(s)
  Konno S、Kobayashi K、Senda M、Funai Y、Seki Y、Tamai I、Schakel L、Sakata K、Pillaiyar T、Taguchi A、Taniguchi A、Gutschow M、Muller CE.、Takeuchi K、Hirohama M、Kawaguchi A、Kojima M、Senda T、Shirasaka Y、Kamitani W、Hayashi Y
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 65 Pages: 2926-2939
- DOI
  10.1021/acs.jmedchem.1c00665
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07137, KAKENHI-PROJECT-20K22723, KAKENHI-PROJECT-19H03475, KAKENHI-PROJECT-21J12536, KAKENHI-PROJECT-20K07165, KAKENHI-PROJECT-21K07036
[Journal Article] ABCG2 requires a single aromatic amino acid to "clamp" substrates and inhibitors into the binding pocket.2020
- Author(s)
  Gose T, Shafi T, Fukuda Y, Das S, Wang Y, Allcock A, Gavan McHarg A, Lynch J, Chen T, Tamai I, Shelat A, Ford RC, Schuetz JD.
- Journal Title
  
  FASEB Journal
  
  Volume: 34 Pages: 4890-4903
- DOI
  10.1096/fj.201902338rr
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05111
[Journal Article] Identification of the Uptake Transporter Responsible for Distribution of Acotiamide into Stomach Tissue.2020
- Author(s)
  Hirayama M, Hoshino Y, Yoshii K, Toda R, Kawabata Y, Nakanishi T, Tamai I.
- Journal Title
  
  Molecular Pharmaceutics
  
  Volume: 17 Pages: 1071-1078
- DOI
  10.1021/acs.molpharmaceut.9b00894
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05111
[Journal Article] Post-transcriptional regulation of OATP2B1 transporter by a microRNA, miR-242020
- Author(s)
  Liu W, Nakano M, Nakanishi T, Nakajima M, Tamai I.
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 35 Issue: 6 Pages: 515-521
- DOI
  10.1016/j.dmpk.2020.07.007
- NAID
  50014656610
- ISSN
  1347-4367
- Data Source
  KAKENHI-PROJECT-20K21474
[Journal Article] Identification of the Catechin Uptake Transporter Responsible for Intestinal Absorption of Epigallocatechin Gallate in Mice.2019
- Author(s)
  Kobayashi M., Nishi K., Mizutani A., Hokama T., Matsue M., Tsujikawa T., Nakanishi T., Nishii R., Tamai I., Kawai K.
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Pages: 13413-13413
- DOI
  10.1038/s41598-019-50049-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19508, KAKENHI-PROJECT-16H05111, KAKENHI-PROJECT-16H05397, KAKENHI-PROJECT-17K10447, KAKENHI-PROJECT-16KK0200
[Journal Article] 4)Changes of drug pharmacokinetics mediated by downregulation of kidney organic cation transporters Mate1 and Oct2 in a rat model of hyperuricemia.2019
- Author(s)
  Nishizawa Kei、Yoda Noriaki、Morokado Fumi、Komori Hisakazu、Nakanishi Takeo、Tamai Ikumi
- Journal Title
  
  PLoS One
  
  Volume: 14 Pages: 0214862-0214862
- DOI
  10.1371/journal.pone.0214862
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15500, KAKENHI-PROJECT-16H05111
[Journal Article] Effect of endogenous multidrug resistance 1 and P-glycoprotein expression on anticancer drug resistance in colon cancer cell lines.2019
- Author(s)
  Washio I, Nakanishi T, Ishiguro N, Bister B, Tamai I.
- Journal Title
  
  Biopharmaceutics and Drug Disposition
  
  Volume: 40 Pages: 32-43
- DOI
  10.1002/bdd.2167
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05111
[Journal Article] Identification of MRP2 as a targetable factor limiting oxaliplatin accumulation and response in gastrointestinal cancer.2019
- Author(s)
  Myint K, Biswas R, Li Y, Jong N, Jamieson S, Liu J, Han C, Squire C, Merien F, Lu J, Nakanishi T, Tamai I, McKeage M.
- Journal Title
  
  Scientific Report
  
  Volume: 9 Pages: 2245-2245
- DOI
  10.1038/s41598-019-38667-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05111
[Journal Article] Sandwich-Cultured Hepatocytes for Mechanistic Understanding of Hepatic Disposition of Parent Drugs and Metabolites by Transporter-Enzyme Interplay.2018
- Author(s)
  Matsunaga N, Fukuchi Y, Imawaka H, Tamai I.
- Journal Title
  
  Drug Metabolism and Disposition
  
  Volume: 46 Pages: 680-691
- DOI
  10.1124/dmd.117.079236
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05111
[Journal Article] Apple-Derived Nanoparticles Modulate Expression of Organic-Anion-Transporting Polypeptide (OATP) 2B1 in Caco-2 Cells.2018
- Author(s)
  Fujita D, Arai T, Komori H, Shirasaki Y, Wakayama T, Nakanishi T, Tamai I.
- Journal Title
  
  Molecular Pharmaceutics
  
  Volume: 15 Pages: 5772-5780
- DOI
  10.1021/acs.molpharmaceut.8b00921
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05111
[Journal Article] Contribution of equilibrative nucleoside transporter(s) to intestinal basolateral and apical transporters of anticancer trifluridine.2018
- Author(s)
  Takahashi K, Yoshisue K, Chiba M, Nakanishi T, Tamai I
- Journal Title
  
  Biopharmaceutics & Drug Disposition
  
  Volume: 39 Pages: 38-46
- DOI
  10.1002/bdd.2110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05111, KAKENHI-PROJECT-16K15158
[Journal Article] Hyperuricemia enhances intracellular urate accumulation via down-regulation of cell-surface BCRP/ABCG2 expression in vascular endothelial cells.2018
- Author(s)
  Hisakazu Komori, Kazuyuki Yamada, Ikumi Tamai
- Journal Title
  
  Biochimica Biophysica Acta
  
  Volume: 1860(5) Pages: 973-980
- DOI
  10.1016/j.bbamem.2018.01.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15500, KAKENHI-PROJECT-16H05111
[Journal Article] 消化管トランスポーター基質を利用した経口DDSの現状と今後の展開2018
- Author(s)
  藤田大地、玉井郁巳
- Journal Title
  
  Drug Delivery System
  
  Volume: 33 Pages: 377-389
- NAID
  130007604264
- Data Source
  KAKENHI-PROJECT-16H05111
[Journal Article] Molecular localization and characterization of multiple binding sites of organic anion transporting polypeptide 2B1 (OATP2B1) as the mechanism for substrate and modulator dependent drug-drug interaction.2017
- Author(s)
  Hoshino Y, Fujita D, Nakanishi T, Tamai I.
- Journal Title
  
  Med Chem Commun
  
  Volume: 7 Pages: 1757-1782
- DOI
  10.1039/c6md00235h
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16H05111
[Journal Article] Revisiting the role of gut wall in the face of orally administered drugs: Why now and to what effect?2017
- Author(s)
  Rostami-Hodjegan A, Tamai I, Pang S.
- Journal Title
  
  Biopharmaceutics & Drug Disposition
  
  Volume: 38 Pages: 87-93
- DOI
  10.1002/bdd.2071
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05111, KAKENHI-PROJECT-16K15158
[Journal Article] Association of miR-145 with statin-induced skeletal muscle toxicity in human rhabdomyosarcoma RD cells.2017
- Author(s)
  Saito S, Nakanishi T, Shirasaki Y, Nakajima M, Tamai I.
- Journal Title
  
  Journal of Pharmaceutical Sciences
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K15158
[Journal Article] Organic Anion Transporting Polypeptide (OATP)2B1 Contributes to Gastrointestinal Toxicity of Anticancer Drug SN-38, Active Metabolite of CPT-11.2017
- Author(s)
  Fujita D, Saito Y, Nakanishi T, Tamai I.
- Journal Title
  
  Drug Metabolism and Disposition
  
  Volume: 44 Pages: 1-7
- DOI
  10.1124/dmd.115.066712
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16H05111
[Journal Article] Local drug-drug interactoin of donepezil with cilostazol at breast cancer resistance protein (ABCG2) increases drug accumulation in heart2016
- Author(s)
  Takeuchi R, Shinozaki K, Nakanishi T, Tamai I
- Journal Title
  
  Drug Metabolism and Disposition
  
  Volume: 44 Pages: 68-74
- DOI
  10.1124/dmd.115.066654
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26670075
[Journal Article] Organic anion transporting polypeptide 2B1 expression correlates with uptake of estrone-3-sulfate and cell proliferation in estrogen receptor-positive breast cancer cells2015
- Author(s)
  Jun Matsumoto, Noritaka Ariyoshi, Masahiro Sakakibara, Takeo Nakanishi, Yoshiyuki Okubo, Nobumitsu Shiina, Kaoru Fujisaki, Takeshi Nagashima, Yukio Nakatani, Ikumi Tamai, Harumi Yamada, Hiroshi Takeda and Itsuko Ishii
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 30 Issue: 2 Pages: 133-141
- DOI
  10.1016/j.dmpk.2014.10.005
- NAID
  210000170465
- ISSN
  1347-4367
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25893224
[Journal Article] Accumulation of trans-1-Amino-3-18F-fluorocyclobutanecarboxylic Acid in Prostate Cancer due to Androgen-induced Expression of Amino-acid Transporters.2014
- Author(s)
  Okudaira H, Oka S, Ono M, Nakanishi T, Shuster DM, Kobayashi M, Goodman MM, Tamai I, Kawai K, Shirakami Y.
- Journal Title
  
  Mol. Imaging Biol.
  
  Volume: 16 Pages: 756-764
- DOI
  10.1007/s11307-014-0756-x
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24601008, KAKENHI-PROJECT-24659558, KAKENHI-PROJECT-25293260
[Journal Article] Transporter-mediated drug interaction2014
- Author(s)
  Hisakazu Komori and Ikumi Tamai
- Journal Title
  
  Folia Pharmacol. Jpn.
  
  Volume: 143 Issue: 5 Pages: 243-248
- DOI
  10.1254/fpj.143.243
- NAID
  130004827696
- ISSN
  0015-5691, 1347-8397
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890073
[Journal Article] Substrate- and dose-dependent drug interactions with grapefruit juice caused by multiple binding sites on OATP2B12014
- Author(s)
  Shirasaka Y, Mori T, Murata Y, Nakanishi T, and Tamai I
- Journal Title
  
  Pharm Res
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590175
[Journal Article] Transport mechanism of hepatic uptake and bile excretion in clinical hepatobiliary scintigraphy with 99mTc-N-pyridoxyl-5-methyltryptophan.2014
- Author(s)
  Kobayashi M, Nakanishi T, Nishi K, Higaki Y, Okudaira H, Ono M, Tsujiuchi T, Mizutani A, Nishii R, Tamai I, Arano Y, Kawai K.
- Journal Title
  
  Nucl. Med. Biol.
  
  Volume: 4 Pages: 338-342
- DOI
  10.1016/j.nucmedbio.2014.01.004
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23300361, KAKENHI-PROJECT-24601008, KAKENHI-PROJECT-24659558, KAKENHI-PROJECT-25293260
[Journal Article] Substrate- and dose-dependent drug interactions with grapefruit juice caused by multiple binding sites on OATP2B1.2014
- Author(s)
  Shirasaka Y, Mori T, Murata Y, Nakanishi T, and Tamai I.
- Journal Title
  
  Pharm Res.
  
  Volume: In Press
- DOI
  10.1007/s11095-014-1305-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590175
[Journal Article] 薬物トランスポーターと相互作用2014
- Author(s)
  小森久和、玉井郁巳
- Journal Title
  
  日本薬理学雑誌
  
  Volume: 143 Pages: 243-248
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890073
[Journal Article] Long-lasting inhibitory effect of apple and orange juices, but not grapefruit juice, on OATP2B1- mediated drug absorption2013
- Author(s)
  Shirasaka Y, Shichiri M, Murata Y, Mori T, Nakanishi T, and Tamai I
- Journal Title
  
  Drug Metab Dispos
  
  Volume: 41(3) Pages: 615-621
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590175
[Journal Article] Major active components in grapefruit, orange and apple juices responsible for OATP2B1-mediated drug interactions.2013
- Author(s)
  Shirasaka Y., Shichiri M, Nakanishi T., and Tamai I.
- Journal Title
  
  J Pharm Sci.
  
  Volume: 102 Pages: 280-288
- DOI
  10.1002/jps.23357
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590175
[Journal Article] MDR1 is related to intestinal epithelial injury induced by acetylsalicylic acid.2013
- Author(s)
  Kugai M, Uchiyama K, Tsuji T, Yoriki H, Fukui A, Qin Y, Higashimura Y, Mizushima K, Yoshida N, Katada K, Kamada K, Handa O, Takagi T, Konishi H, Yagi N, Yoshikawa T, Shirasaka Y, Tamai I, Naito Y, and Itoh Y.
- Journal Title
  
  Cell Physiol Biochem.
  
  Volume: 32 Pages: 942-950
- DOI
  10.1159/000354497
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590175, KAKENHI-PROJECT-25750050
[Journal Article] Kinetic Analyses of Trans-1-amino-3-18F-fluorocyclobutanecarboxylic Acid Transport in Xenopus Laevis Oocytes Expressing Human ASCT2 and SNAT2.2013
- Author(s)
  Okudaira H, Nakanishi T, Oka S, Kobayashi M, Tamagami H, Schuster DM, Goodman MM, Shirakami Y, Tamai I, Kawai K.
- Journal Title
  
  Nucl. Med. Biol.
  
  Volume: 40 Pages: 670-675
- DOI
  10.1016/j.nucmedbio.2013.03.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24601008, KAKENHI-PROJECT-24659558, KAKENHI-PROJECT-25293260
[Journal Article] Major active components in grapefruit, orange and apple juices responsible for OATP2B1-mediated drug interactions.2013
- Author(s)
  Shirasaka Y, Shichiri M, Mori T, Nakanishi T, and Tamai I.
- Journal Title
  
  J Pharm Sci.
  
  Volume: 102 Pages: 3418-3426
- DOI
  10.1002/jps.23653
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590175
[Journal Article] Long-lasting inhibitory effect of apple and orange juices, but not grapefruit juice, on OATP2B1-mediated drug absorption.2013
- Author(s)
  Shirasaka Y., Shichiri M, and Tamai I.
- Journal Title
  
  Drug Metab Dispos.
  
  Volume: 41 Pages: 615-621
- DOI
  10.1124/dmd.112.049635
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590175
[Journal Article] MDR1 is related to intestinal epithelial injury induced by acetylsalicylic acid2013
- Author(s)
  Kugai M, Uchiyama K, Tsuji T, Yoriki H, Fukui A, Qin Y, Higashimura Y, Mizushima K, Yoshida N, Katada K, Kamada K, Handa O, Takagi T, Konishi H, Yagi N, Yoshikawa T, Shirasaka Y, Tamai I, Naito Y, and Itoh Y
- Journal Title
  
  Cell Physiol Biochem
  
  Volume: 32(4) Pages: 942-950
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590175
[Journal Article] Major active components in grapefruit, orange and apple juices responsible for OATP2B1-mediated drug interactions2013
- Author(s)
  Shirasaka Y, Shichiri M, Mori T, Nakanishi T, and Tamai I
- Journal Title
  
  J Pharm Sci
  
  Volume: 102(9) Pages: 3418-3426
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590175
[Journal Article] A Putative Role of Organic Anion Transporting Polypeptides (OATPs) In Cell Survival of Hormone-Dependent Breast and Prostate Cancers2013
- Author(s)
  Nakanishi T, Tamai I
- Journal Title
  
  J Cancer Res Therap Oncol
  
  Volume: 1 Pages: 1-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590176
[Journal Article] Extra-renal elimination of uric acid via intestinal efflux transporter BCRP/ABCG22012
- Author(s)
  Hosomi A., Nakanishi T., Fujita T., Tamai I.
- Journal Title
  
  PLoS One
  
  Volume: 7(2)
- NAID
  120003959482
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390044
[Journal Article] Enhanced Expression of Organic Anion Transporting Polypeptides (OATPs) in Androgen Receptor-positive Prostate Cancer Cells: Possible Role of OATP1A2 in Adaptive Cell Growth under Androgen-depleted Conditions.2012
- Author(s)
  Arakawa H, Nakanishi T, Yanagihara C, Nishimoto T, Wakayama T, Mizokami A, Namiki M, Kawai K, Tamai I.
- Journal Title
  
  Biochem. Pharmacol.
  
  Volume: 84 Pages: 1070-1077
- DOI
  10.1016/j.bcp.2012.07.026
- NAID
  120004997008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590176, KAKENHI-PROJECT-24659558
[Journal Article] Extra-renal elimination of uric acid via intestinal efflux transporter BCRP/ABCG22012
- Author(s)
  Hosomi A, Nakanishi T, Fujita T, Tamai I
- Journal Title
  
  PLoS One
  
  Volume: 7(2)
- NAID
  120003959482
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390044
[Journal Article] Involvement of Functional Groups on the Surface of Carboxyl Group-Terminated Polyamidoamine Dendrimers Bearing Arbutin in Inhibition of Na(+)/Glucose Cotransporter 1 (SGLT1)-Mediated d-Glucose Uptake.2012
- Author(s)
  Sakuma S., Kanamitsu S., Teraoka Y., Masaoka Y., Kataoka M., Yamashita S., Shirasaka Y., Tamai I., Muraoka M., Nakatsuji Y., Kida T., and Akashi M.
- Journal Title
  
  Mol Pharm.
  
  Volume: 9 Pages: 922-929
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590175
[Journal Article] Synthesis of [^<11>C]uric acid, using [^<11>C] phosgene, as a possible biomarker in PET imaging for diagnosis of gout2012
- Author(s)
  Yashio K, Katayama Y, Takashima T, Ishiguro N, Doi H, Suzuki M, Wada Y, Tamai I, Watanabe Y
- Journal Title
  
  Bioorg Med Chem Lett
  
  Volume: 22(1) Pages: 115-9
- DOI
  10.1016/j.bmcl.2011.11.055
- NAID
  120003752522
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390044
[Journal Article] Application of quantitative time-lapse imaging (QTLI) for evaluation of Mrp2-based drug-drug interaction induced by liver metabolites.2012
- Author(s)
  Nakanishi T, Ikenaga M, Fukuda H, Matsunaga N, Tamai I.
- Journal Title
  
  Toxicology and Applied Pharmacology
  
  Volume: 263 Pages: 244-250
- Data Source
  KAKENHI-PROJECT-23659076
[Journal Article] Application ofquantitative time-lapse imaging(QTLI) for evaluation of Mrp2-baseddrug-drug interaction induced byliver metabolites.2012
- Author(s)
  Nakanishi T, Ikenaga M, Fukuda H, Matsunaga N, Tamai I
- Journal Title
  
  Toxicol ApplPharmacol
  
  Volume: 263(2) Pages: 244-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659076
[Journal Article] Synthesis of[^<11> C] uric acid, using[^<11> C] phosgene, as a possible biomarker in PET imaging for diagnosis of gout2012
- Author(s)
  Yashio K., Katayama Y., Takashima T., Ishiguro N., Doi H, Suzuki M., Wada Y., Tamai I., Watanabe Y.
- Journal Title
  
  Bioorg Med Chem Lett
  
  Volume: 22(1) Pages: 115-9
- NAID
  120003752522
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390044
[Journal Article] Functional pleiotropy of organic anion transporting polypeptide OATP2B1 due to multiple binding sites.2012
- Author(s)
  Shirasaka Y., Mori T., Shichiri M., Nakanishi T., and Tamai I.
- Journal Title
  
  Drug Metab Pharmacokinet
  
  Volume: In press
- NAID
  130004463259
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590175
[Journal Article] Functional pleiotropy of organic anion transporting polypeptide OATP2B1 due to multiple binding sites2012
- Author(s)
  Shirasaka Y, Mori T, Shichiri M, Nakanishi T, and Tamai I
- Journal Title
  
  Drug Metab Pharmacokinet
  
  Volume: 27(3) Pages: 360-364
- NAID
  130004463259
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590175
[Journal Article] Involvement of Functional Groups on the Surface of Carboxyl Group-Terminated Polyamidoamine Dendrimers Bearing Arbutin in Inhibition of Na(+)/Glucose Cotransporter 1 (SGLT1)-Mediated d-Glucose Uptake2012
- Author(s)
  Sakuma S, Kanamitsu S, Teraoka Y, Masaoka Y, Kataoka M, Yamashita S, Shirasaka Y, Tamai I, Muraoka M, Nakatsuji Y, Kida T, and Akashi M
- Journal Title
  
  Mol Pharm
  
  Volume: 9(4) Pages: 922-929
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590175
[Journal Article] Active intestinal absorption of fluoroquinolone antibacterial agent ciprofloxacin by organic anion transporting polypeptide.2012
- Author(s)
  Arakawa H., Shirasaka Y., Haga M., Nakanishi T., and Tamai I.
- Journal Title
  
  Biopharm Drug Dispos.
  
  Volume: 33 Pages: 332-341
- DOI
  10.1002/bdd.1809
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590175
[Journal Article] Active intestinal absorption of fluoroquinolone antibacterial agent ciprofloxacin by organic anion transporting polypeptide, Oatp1a52012
- Author(s)
  Arakawa H, Shirasaka Y, Haga M, Nakanishi T, and Tamai I
- Journal Title
  
  Biopharm Drug Dispos
  
  Volume: 33(6) Pages: 332-341
- NAID
  120004997009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590175
[Journal Article] Quantitative time-lapse imaging (QTLI)-based analysis of drug-drug interaction mediated by hepatobiliary transporter, multidrug associated protein 2, in sandwich-cultured rat hepatocytes2011
- Author(s)
  Takeo Nakanishil, Yuta Shibuel, Yoko Fukuyamal, Kenji Yoshida2, Hajime Fukudal, Yoshiyuki Shirasakal, Ikumi Tamail, 2
- Journal Title
  
  Drug Metab.Dispos.
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659038
[Journal Article] Quantitative time-lapse imaging-based analysis of drug-drug interaction mediated by hepatobiliary transporter, multidrug resistance-associated protein 2, in sandwich-cultured rat hepatocytes.2011
- Author(s)
  Nakanishi T., Shibue Y., Fukuyama Y., Yoshida K., Fukuda H., Shirasaka Y., Tamai I
- Journal Title
  
  Drug Metabolism Disposition
  
  Volume: 39(6) Pages: 984-991
- DOI
  10.1124/dmd.111.038059
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659076
[Journal Article] Identification and functional characterization of uric acid transporter Uratl (Slc22a12) in rats.2011
- Author(s)
  Sato M, Wakayama T, Mamada H, Shirasaka Y, Nakanishi T, Tamai I.
- Journal Title
  
  Biochim Biophys Acta.
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390044
[Journal Article] Organic cation transporter-mediated renal secretion of ipratropium and tiotropium in rats and humans.2011
- Author(s)
  Nakanishi T, Haruta T, Shirasaka Y, Tamai I
- Journal Title
  
  Drug Metab Dispos.
  
  Volume: 39(1) Pages: 117-122
- DOI
  10.1124/dmd.110.035402
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390044
[Journal Article] Functional Characterization of Apical Transporters Expressed in Rat Proximal Tubular Cells(PTCs) in Primary Culture2011
- Author(s)
  Nakanishi T., Fukushi A., Sato M., Yoshifuji M., Gose T., Shirasaka Y., Ohe K., Kobayashi M., Kawai K., Tamai I
- Journal Title
  
  Mol. Pharm
  
  Volume: 8 Pages: 2142-2150
- Data Source
  KAKENHI-PROJECT-21659286
[Journal Article] Intestinal Absorption Mechanism of Tebipenem Pivoxil, a Novel Oral Carbapenem : Involvement of Human OATP Family in Apical Membrane Ti-ansport.2011
- Author(s)
  Kato K., Shirasaka Y., Kuraoka E., Kikuchi A., Iguchi M., Suzuki H., Shirasaka S., Kurosawa T., Tamai I.
- Journal Title
  
  Mol.Pharm
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659038
[Journal Article] Functional characterization of apical transporters expressed inrat proximal tubular cells (PTCs) in primary culture2011
- Author(s)
  Nakanishi T., Fukushi A., Sato M., Yoshifuji M., Gose T., Shirasaka Y., Ohe K., Kobayashi M., Kawai K., Tamai I.
- Journal Title
  
  Mol Pharm
  
  Volume: 8(6) Pages: 2142-50
- DOI
  10.1021/mp200096r
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390044
[Journal Article] Differential effect of grapefruit juice on intestinal absorption of statins due to inhibition of organic anion transporting polypeptide and/or P-glycoprotein.2011
- Author(s)
  Shirasaka Y., Suzuki K., Nakanishi T., and Tamai I.
- Journal Title
  
  J Pharm Sci
  
  Volume: 100 Pages: 3843-3853
- DOI
  10.1002/jps.22586
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590175
[Journal Article] Intestinal Absorption of HMG-CoA Reductase Inhibitor Pitavastatin Mediated by Organic Anion Transporting Polypeptide and P-Glycoprotein/Multidrug Resistance 1.2011
- Author(s)
  Shirasaka Y, Suzuki K, Shichiri M, Nakanishi T, Tamai I.
- Journal Title
  
  Drug Metab Pharmacokinet.
  
  Volume: in press
- NAID
  130004463175
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659038
[Journal Article] Putative Transport Mechanism and Intracellular Fate of Anti-18F-FACBC(Trans-1-amino-3-F^<18>-fluorocyclobutanecarboxylic Acid) in Human Prostate Cancer2011
- Author(s)
  Okudaira H., Shikano N., Nishii R., Miyagi T., Yoshimoto M., Kobayashi M., Ohe K., Nakanishi T., Tamai I., Namiki M., Kawai K
- Journal Title
  
  J. Nucl. Med
  
  Volume: 52 Pages: 822-829
- Data Source
  KAKENHI-PROJECT-21659286
[Journal Article] Identification and functional characterization of uric acid transporter Urat1(Slc22a12) in rats2011
- Author(s)
  Sato M., Wakayama T., Mamada H., Shirasaka Y., Nakanishi T., Tamai I.
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: 1808(6) Pages: 1441-1447
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390044
[Journal Article] Hepatic Uptake of {gamma}-Butyrobetaine, a Precursor of Carnitine Biosynthesis, in Rats.2010
- Author(s)
  Fujita M, Nakanishi T, Shibue Y, Kobayashi D, Moseley RH, Shirasaka Y, Tamai I.
- Journal Title
  
  Am.J.Physiol.Gastrointest Liver Physiol. (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659038
[Journal Article] Quantitation of Talinolol in Rat Plasma By LC-MS-MS.2010
- Author(s)
  Li Y., Shirasaka Y., Langguth P.Tamai I
- Journal Title
  
  J.Chromatogr Sci.
  
  Volume: 48 Pages: 367-370
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659038
[Journal Article] Transport of ipratropium, an anti-chronic obstructive pulmonary disease(COPD)drug, is mediated by organic cation/carnitine transporters in human bronchial epithelial cells : Implications for carrier-mediated pulmonary absorption.2010
- Author(s)
  Nakamura T, Nakanishi T, Haruta T, Shirasaka Y, Keogh JP, Tamai I.
- Journal Title
  
  Molecular Pharmaceutics 7
  
  Pages: 187-195
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659038
[Journal Article] Hepatic Uptake of {gamma}-Butyrobetaine, a Precursor of Carnitine Biosynthesis, in Rats2010
- Author(s)
  Fujita M, Nakanishi T, Shibue Y, Kobayashi D, Moseley RH, Shirasaka Y, Tamai I.
- Journal Title
  
  Am.J.Physiol.Gastrointest Liver Physiol (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390044
[Journal Article] Renal Secretion of Uric Acid by Organic Anion Transporter 2 (OAT2/SLC22A7) in Human2010
- Author(s)
  Sato M., Mamada H., Anzai N., Shirasaka Y., Nakanishi T., Tamai I.
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume: 33(3) Issue: 3 Pages: 498-503
- DOI
  10.1248/bpb.33.498
- NAID
  130000248105
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390044
[Journal Article] Estimation of transporters involved in the hepatobiliary transport of TA-0201CA using sandwich-cultured rat hepatocytes from normal and Mrp2-deficient rats.2010
- Author(s)
  Fukuda H., Ohashi R., Ohashi N., Yabuuchi H., Tamai I.
- Journal Title
  
  Drug Metab.Dispos
  
  Volume: 38 Pages: 1505-1513
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659038
[Journal Article] Angiotensin II Receptor Blockers Induce Alteration of Serum Uric Acid Level via Renal Uric Acid Transporters, A Review of the Authors' Current Research, 33, 149-161 (2009)2010
- Author(s)
  Sato M., Anzai N., Tamai I.
- Journal Title
  
  Gout and Nucleic Acid Research 33
  
  Pages: 149-161
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390044
[Journal Article] Renal secretion of uric acid by organic anion transporter 2 (OAT2/SLC22A7)2010
- Author(s)
  Sato M., Mamada H., Anzai N., Shirasaka Y., Nakanishi T., Tamai I.
- Journal Title
  
  Biol.Pharm.Bull.
  
  Volume: 33(3) Pages: 498-503
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390044
[Journal Article] Renal secretion of uric acid by organic anion transporter 2 (OAT2/SLC22 A7)2010
- Author(s)
  Sato M., Mamada H., Anzai N., Shirasaka Y., Nakanishi T., Tamai I.
- Journal Title
  
  Biol.Pharm.Bull. 33
  
  Pages: 498-503
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390044
[Journal Article] Carboxyl group-terminated polyamidoamine dendrimers bearing glucosides inhibit intestinal hexose transporter-mediated D-glucose uptake2010
- Author(s)
  Shinji Sakuma, Yumi Teraoka, Tomokazu Sagawa, Yoshie Masaoka, Makoto Kataoka, Shinji Yamashita, Yoshiyuki Shirasaka, Ikumi Tamai, Yusuke Ikumi, Toshiyuki Kida, Mitsuru Akashi
- Journal Title
  
  Eur. J. Pharm. Biopharm
  
  Volume: 75(3) Pages: 366-374
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590051
[Journal Article] Transport of ipratropium, an anti-chronic obstructive pulmonary diseasedrug, is mediated by organic cat ionlcarnitine transporters in human bronchial epithelial cells : implications for carrier-mediated pulmonary absorption.2010
- Author(s)
  Nakamura T., Nakanishi T., Haruta T., Shirasaka Y., Keogh JP., Tamai I.
- Journal Title
  
  Mol.Phann.
  
  Volume: 7 Pages: 187-195
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659038
[Journal Article] Intestinal absorption of HMG-CoA reductase inhibitor pravastatin mediated by organic anion transporting polypeptide.2010
- Author(s)
  Shirasaka Y., Suzuki K., Nakanishi T., Tamai I.
- Journal Title
  
  Pharw.Res.
  
  Volume: 27 Pages: 2141-2149
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659038
[Journal Article] Involvement of choline Iransporter-like (CTL) proteins, CTL1 and CTL2, in glucocorticoid-induced acceleration of phosphatidylcholine syniesis via increased choline uptake.2010
- Author(s)
  Nakamura R., Ishigaro N., Oyabu M., Nakanishi T., Shirasaka Y., Maeda T., Tamai I
- Journal Title
  
  Biol Pharm.Bull.
  
  Volume: 33(4) Pages: 691-696
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659038
[Journal Article] Involvement of choline transporter-like(CTL)proteins, CTL1 and CTL2, in glucocorticoid-induced acceleration of phosphatidylcholine syntesis via increased choline uptake.2010
- Author(s)
  Nakamura R., Ishiguro N., Oyabu M., Nakanishi T., Shirasaka Y., Maeda T., Tamai I.
- Journal Title
  
  Biol.Pharm.Bull. 33(In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659038
[Journal Article] Angiotensin II Receptor Blockers Induce Alteration of Serum Uric Acid Level via Renal Uric Acid Transporters2009
- Author(s)
  Sato M., Anzai N., Tamai I.
- Journal Title
  
  Gout and Nucleic Acid Research
  
  Volume: 33 Pages: 149-161
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390044
[Journal Article] Organic Anion Transporter OAT1 Is Involved in Renal Handling of Citrulline2009
- Author(s)
  Nakakariya M, Shima Y, Shirasaka Y, Mitsuoka K, Nakanishi T, Tamai I.
- Journal Title
  
  Am.J.Physiol.Renal Physiol. 297
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390044
[Journal Article] Hepatic Uptake of{ gamma}-Butyrobetaine, a Precursor of Carnitine Biosynthesis2009
- Author(s)
  Fujita M., Nakanishi T., Shibue Y., Kobayashi D., Moseley RH., Shirasaka Y., Tamai I.
- Journal Title
  
  Gastrointest Liver Physiol
  
  Volume: 297
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390044
[Journal Article] Concentration-dependent effect of naringin on intestinal absorption of betal-adrenoreceptor antagonist talinolol mediated by P-glycoprotein and organic anion transporting Polypeptide(Oatp).2009
- Author(s)
  Shirasaka Y, Li Y, Shibue Y, Kuraoka E, Spahn-Langguth H, Kato Y, Langguth P, Tamai I.
- Journal Title
  
  Pharm.Res. 26
  
  Pages: 560-570
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659038
[Journal Article] Oseltamivir (Tamiflu^<TM>) is a substrate of PEPT1.2009
- Author(s)
  Ogihara T, Kano T, Wagatsuma T, Wada S, Yabuuchi H, Enomoto S, Morimoto K, Shirasaka Y, Kobayashi S, Tamai I.
- Journal Title
  
  Drug Metab.Dispos. 37
  
  Pages: 1671-1681
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659038
[Journal Article] Organic Anion Transporter OAT1 Is Involved in Renal Handling of Citrulline2009
- Author(s)
  Nakakariya M., Shima Y., Shirasaka Y., Mitsuoka K., Nakanishi T., Tamai I.
- Journal Title
  
  Am. J. Physiol
  
  Volume: 297
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390044
[Journal Article] 動態における薬物トランスポーターの役割、消化管と肝臓2009
- Author(s)
  玉井郁巳
- Journal Title
  
  (株)メディカルドゥ
- Data Source
  KAKENHI-PROJECT-19390046
[Journal Article] Oseltamivir (Tamiflu) Efflux Transport at the Blood-Brain Barrier via P-glycoprotein.2008
- Author(s)
  Morimoto K, Nakakariya M, Shirasaka Y, Kakinuma C, Fujita T, Tamai I, Ogihara T.
- Journal Title
  
  Drug Metab Dispos 36
  
  Pages: 6-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19599023
[Journal Article] Predominant contribution of rat organic anion transporting polypeptide-2 (Oatp2) to hepatic uptake of beta-lactam antibiotics.2008
- Author(s)
  Nakakariya M, Shimada T, Irokawa M, Koibuchi H, Iwanaga T, Yabuuchi H, Maeda T, Tamai I.
- Journal Title
  
  Pharm. Res. 25
  
  Pages: 578-585
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390046
[Journal Article] Involvement of organic anion transporting polypeptide 1a5 (Oatp1a5) in the intestinal absorption of endothelin receptor antagonist in rats2008
- Author(s)
  Tani, T., Gram, LK., Arakawa, H., Kikuchi, A., Chiba, M., Ishii, Y., Steffansen, B., Tamai, I.
- Journal Title
  
  Phram. Res 25
  
  Pages: 1085-1091
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390046
[Journal Article] Effect of plasma protein binding on in vitro-in vivo correlation of biliary excretion of drugs evaluated by sandwich-cultured rat hepatocytes2008
- Author(s)
  Fukuda H., Ohashi R., Tsuda-Tsukimoto M., Tamai I.
- Journal Title
  
  Drug Metab. Dispos 36
  
  Pages: 1275-1282
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390046
[Journal Article] Identification and species similarity of OATP transporters responsible for hepatic uptake of s-lactam antibiotics2008
- Author(s)
  Nakakariya M., Shimada T., Irokawa M., Maeda T., Tamai I.
- Journal Title
  
  Drug Metab. Pharmacoki 23(5)
  
  Pages: 347-355
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390046
[Journal Article] Effect of plasma protein binding on in vitro-in vivo correlation of biliary excretion of drugs evaluated by sandwich-cultured rat hepatocytes.2008
- Author(s)
  Fukuda H, Ohashi R, Tsuda-Tsukimoto M, Tamai I.
- Journal Title
  
  Drug Metab. Dispos. 36
  
  Pages: 1275-1282
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390046
[Journal Article] Effect of glucocorticoid receptor ligand dexamethasone on the expression of the organic cation transport in rat liver2008
- Author(s)
  Maeda T., Yotsumoto T., Oyabu M., Tamai I.
- Journal Title
  
  Drug Metab. Pharmacoki 23(1)
  
  Pages: 67-72
- NAID
  10024187802
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390046
[Journal Article] Characterization of Oatp-mediated hepatic uptake of nafcillin, a high biliary excretion type of β-lactam antibiotics2008
- Author(s)
  Nakakariya M., Shimada D., Koibuchi H., Irokawa M., Iwanaga T., Yabuuchi H., Maeda T., Tamai I.
- Journal Title
  
  Pharm. Res 25(3)
  
  Pages: 578-585
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390046
[Journal Article] Involvement of Organic Anion Transporting Polypeptide la 5(Oatp la5)in the Intestinal Absorption of Endothelin Receptor Antagonist in Rats.2008
- Author(s)
  Tani T, Gram LK, Arakawa H, Kikuchi A, Chiba M, Ishii Y, Steffansen B, Tamai I
- Journal Title
  
  Pharmaceutical Research. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390046
[Journal Article] Identification and species similarity of OATP transporters responsible for hepatic uptake of beta-lactam antibiotics.2008
- Author(s)
  Nakakariya M, Shimada T, Irokawa M, Maeda T, Tamai I.
- Journal Title
  
  Drug Metab. Pharmacokinet. 23
  
  Pages: 347-355
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390046
[Journal Article] Predominant Contribution of Rat Organic Anion Transporting Polypeptide-2(Oatp2)to Hepatic Uptake of beta-Lactam Antibiotics.2008
- Author(s)
  Nakakariya M, Shimada T, Irokawa M, Koibuchi H, Iwanaga T, Yabuuchi H, Maeda T, Tamai I
- Journal Title
  
  Pharmaceutical Research. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390046
[Journal Article] Effect of glucocorticoid receptor ligand dexamethasone on the expression of the organic cation transport in rat liver.2008
- Author(s)
  Maeda T., Yotsumoto T., Oyabu M., Tamai I.
- Journal Title
  
  Drug Metab. Pharmacoki. 23
  
  Pages: 67-72
- NAID
  10024187802
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390046
[Journal Article] Mechanism of the Regulation of OCTN1 Transporter (SLC22A4) by Rheumatoid Arthritis-Associated Transcriptional Factor RUNX1 and Inflammatory Cytokines.2007
- Author(s)
  Maeda T, Hirayama M, Kobayashi D, Miyazawa K, Tamai I
- Journal Title
  
  DRUG METABOLISM AND DISPOSITION 35
  
  Pages: 394-401
- Data Source
  KAKENHI-PROJECT-17659049
[Journal Article] Decreased Proliferation and Erythroid Differentiation of K562 Cells by siRNA-induced Depression of OCTN1 (SLC22A4) Transporter Gene.2007
- Author(s)
  Nakamura T, Sugiura S, Kobayashi D, Yoshida K, Yabuuchi Y, Aizawa S, Maeda T, Tamai I
- Journal Title
  
  PHARMACEUTICAL RESEARCH (in press)
- Data Source
  KAKENHI-PROJECT-17659049
[Journal Article] Characterization of Human OATP2B1 (SLCO2B1) Gene Promoter Regulation.2006
- Author(s)
  Maeda T., Hirayama M., Higashi R., Sato M., Tamai I.
- Journal Title
  
  PHARMACEUTICAL RESEARCH 23
  
  Pages: 513-520
- Data Source
  KAKENHI-PROJECT-17659049
[Journal Article] L-arginine import via cationic amino acid transporter CAT1 is essential for both differentiation and proliferation of erythrocytes.2006
- Author(s)
  Shima Y, Maeda T, Aizawa S, Tsuboi I, Kobayashi D, Kato R, Tamai I.
- Journal Title
  
  BLOOD 107
  
  Pages: 1352-1356
- Data Source
  KAKENHI-PROJECT-17659049
[Journal Article] Role of polyamine derived from arginine in differentiation and proliferation of human blood cells.2006
- Author(s)
  Maeda T, Wakasawa T, Shima Y, Tsuboi I, Aizawa S, Tamai I.
- Journal Title
  
  BIOLOGICAL & PHARMACEUTICAL BULLETIN 29
  
  Pages: 231-239
- NAID
  110005663951
- Data Source
  KAKENHI-PROJECT-17659049
[Journal Article] Suppression of cell proliferation by inhibition of estrone-3-sulfate transporter in estrogen-dependent breast cancer cells.2005
- Author(s)
  Nozawa T, Suzuki M, Yabuuchi H, Irokawa M, Tshji A, Tamai I.
- Journal Title
  
  PHARMACEUTICAL RESEARCH. 22
  
  Pages: 1634-1641
- Data Source
  KAKENHI-PROJECT-17390046
[Journal Article] Suppression of cell proliferation by inhibition of estrone-3-sulfate transporter in estrogen-dependent breast canser cells2005
- Author(s)
  Nozawa T, Suzuki M, Yabuuchi H, Irokawa, M, Tsuji A, Tamai I
- Journal Title
  
  Pharmaceutical Research 22
  
  Pages: 1634-1641
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390046
[Journal Article] Role of organic anion transporter OATP1B2 (OATP-C) in hepatic uptake of iripotecan and its active metabolite, ------2005
- Author(s)
  Nozawa T., Minami H., Sugiura S., Tsuji A., Tamai I.
- Journal Title
  
  DRUG METABOLISMM AND DISPOSITION 33(3)
  
  Pages: 434-439
- Data Source
  KAKENHI-PROJECT-15390051
[Journal Article] Involvement of estrone-3-sulfate transporters in proliferation of hormone=dependent breast cancer cells.2004
- Author(s)
  Nozawa T, Suzuki M, Takahashi K, Yabuuchi H, Tamai I
- Journal Title
  
  Journal of Pharmacology and Experimental Therapeutics 311(3)
  
  Pages: 1032-1037
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390046
[Journal Article] Involvement of OCTN1(SLC22A4) in pH-dependent transport of organic cations2004
- Author(s)
  Tamai I. et al.
- Journal Title
  
  Molecular Pharmaceutics 1
  
  Pages: 57-66
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390051
[Journal Article] Functional Characterization of pH-Sensitive Organic Anion Transporting Polypeptide OATP-B in Human2004
- Author(s)
  Nozawa T., Imai K., Nezu J., Tsuji A., Tamai I.
- Journal Title
  
  JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 308(2)
  
  Pages: 438-445
- Data Source
  KAKENHI-PROJECT-15390051
[Journal Article] Involvement of OCTN1(SLC22A4) in pH-Dependent Transport of Organic Cation2004
- Author(s)
  Ikumi Tamai
- Journal Title
  
  Molecular Pharmaceutics 1
  
  Pages: 57-66
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390051
[Journal Article] Involvement of OCTNI(SLC22A4)in pH-Dependent Transport of Organic Cation2003
- Author(s)
  Ikumi Tamai
- Journal Title
  
  Molecular Phamaceutics Vol.11 No.1
  
  Pages: 55-66
- Data Source
  KAKENHI-PROJECT-15390389
[Journal Article] Involvement of OCTN1(SLC22A4) in pH-Dependent Transport of Organic Cation2003
- Author(s)
  Ikumi Tamai
- Journal Title
  
  Molecular Pharmaceutidcs Vol.11,No.1
  
  Pages: 55-66
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390389
[Journal Article] Enhanced Intestinal Absorption of Drugs by Activation of Peptide Transporter PEPT1 Using Proton-Releasing Polymer2003
- Author(s)
  Ikumi Tamai
- Journal Title
  
  J.Pharmaceutical Science Vol.92 No.11
  
  Pages: 2208-2216
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13557104
[Journal Article] Enhanced Intestinal Absorption of Drugs by Activation of Peptide Transporter PEPT1 Using Proton-Releasing Polymer.2003
- Author(s)
  Ikumi Tamai
- Journal Title
  
  Journal of Pharmaceutical Science Vol.92, No. 11
  
  Pages: 2208-2216
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390389
[Journal Article] Involvement of OCTN1(SLC22A4) in pH-Dependent Transport of Organic Cation2003
- Author(s)
  Ikumi Tamai
- Journal Title
  
  Molecular Pharmaceutidcs Vol.11, No.1
  
  Pages: 55-66
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13557104
[Journal Article] Enhanced Intestinal Absorption of Drugs by Activation of Peptide Transporter PEPT1 Using Proton-Releasing Polymer.2003
- Author(s)
  Ikumi Tamai
- Journal Title
  
  Journal Of Pharmaceutical Science Vol.92, No.11
  
  Pages: 2208-2216
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13557104
[Journal Article] Enhanced Intestinal Absorption of Drugs by Activation of Peptide Transporter PEP T1 Using Proton-Releasing Polymer2003
- Author(s)
  Ikumi Tamai
- Journal Title
  
  Journal of Pharmaceutical Science Vol.92 No.11
  
  Pages: 2208-2216
- Data Source
  KAKENHI-PROJECT-15659308
[Journal Article] Enhanced Intestinal Absorption of Drugs by Activation of Peptide Tranporter PEPT1 Using Proton-Releasing Ploymer2003
- Author(s)
  Ikumi Tamai
- Journal Title
  
  Jounal of Pharmaceutical Science Vol.92,No.11
  
  Pages: 2208-2216
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390389
[Journal Article] Involvement of OCTN1 (SLC22A4) in pH-Dependent Transport of Organic2003
- Author(s)
  Ikumi Tamai
- Journal Title
  
  Molecular Pharmaceutidcs Vol.11, No.1
  
  Pages: 55-66
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13557104
[Journal Article] Enhanced Intestinal Absorption of Drugs by Activation of Peptide Transporter PEP T1 Using Proton-Releasing Polymer2003
- Author(s)
  Ikumi Tamai
- Journal Title
  
  Journal of Pharmaceutical Science Vol.92 No.11
  
  Pages: 2208-2216
- Data Source
  KAKENHI-PROJECT-15390389
[Journal Article] Involvement of human organic anion transporting polypeptide OATP-B (SLC21A9) in pH-dependent transport across intestinal apical membrane2003
- Author(s)
  Kobayashi D., Nozawa T., Imai K., Nezu J., Tsuji A., Tamai I.
- Journal Title
  
  JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 306(2)
  
  Pages: 703-708
- Data Source
  KAKENHI-PROJECT-15390051
[Journal Article] Involvement of OCTN1 (SLC22A4) in pH-Dependent Transport of Organic Cation.2003
- Author(s)
  Ikumi Tamai
- Journal Title
  
  Molecular Pharmaceutidcs (11), 1
  
  Pages: 55-66
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390389
[Journal Article] Involvement of functional groups on the surface of carboxyl group-terminated polyamidoamine dendrimers bearing arbutin in inhibition of Na+/glucose cotransporter 1(SGLT1)-mediated D-glucose uptake
- Author(s)
  Shinji Sakuma, Shun Kanamitsu, Yumi Teraoka, Yoshie Masaoka, Makoto Kataoka, Shinji Yamashita, Yoshiyuki Shirasaka, Ikumi Tamai, Masahiro Muraoka, Yohji Nakatsuji, Toshiyuki Kida, Mitsuru Akashi
- Journal Title
  
  Mol. Pharmaceutics
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590051
[Journal Article] Oseltamivir (Tamiflu^<TM>) is a substrate of PEPT1.
- Author(s)
  Ogihara T, Kano T, Wagatsuma T, Wada S, Yabuuchi H, Enomoto S, Morimoto K, Shirasaka Y, Kobayashi S, Tamai I.
- Journal Title
  
  Drug Metab Dispos in press
  
  Pages: 0-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19599023
[Journal Article] Identification of transporter molecule responsible in the uptake of conjugated form of estrigen by hormone-dependent breast cancer cells.
- Author(s)
  Irokawa M., Nozawa T., Kuraoka E, Suzuki M., Maeda T., Tamai I.
- Journal Title
  
  (In preparation)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390046
[Patent] 分子イメージングにより代謝機能を測定するための検査薬2012
- Inventor(s)
  川井恵一、玉井郁巳、国嶋崇隆太、中西猛夫、小林正和
- Industrial Property Rights Holder
  金沢大学
- Industrial Property Number
  2012-044231
- Filing Date
  2012-02-29
- Data Source
  KAKENHI-PROJECT-23659076
[Presentation] 薬物の消化管初回通過代謝における膜透過性/代謝活性の相互干渉とその細胞動態解析2022
- Author(s)
  八杉優護、白坂善之、鈴木悟、玉井郁巳
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20K07165
[Presentation] CD38 activation contributes to gouty inflammation in vitro2022
- Author(s)
  Wen S, Arakawa S, Tamai I.
- Organizer
  日本痛風・尿酸核酸学会総会
- Data Source
  KAKENHI-PROJECT-21H02641
[Presentation] Quantitative analysis of the effect of osmolality on beverage-drug interaction by evaluating saccharide absorption2021
- Author(s)
  Miyuki Takemura, Yoshiyuki Shirasaka, Kazuki Inanaga, Sayaka Ogi, Ikumi Tamai
- Organizer
  日本薬物動態学会第36回年会
- Data Source
  KAKENHI-PROJECT-20K07165
[Presentation] Quantitative analysis of the effect of absorption characteristics on CYP3A-mediated intestinal drug-drug interactions using physiologically based pharmacokinetic absorption model2021
- Author(s)
  Satoru Suzuki, Yoshiyuki Shirasaka, Emika Murayama, Ikumi Tamai
- Organizer
  日本薬物動態学会第36回年会
- Data Source
  KAKENHI-PROJECT-20K07165
[Presentation] リンゴ由来ナノ粒子中の高分子成分による回腸胆汁酸輸送体ASBTの発現調節2021
- Author(s)
  臼井紳也、小森久和、岩本結、稲永上輝、白坂善之、玉井郁巳
- Organizer
  第133回日本薬学会北陸支部
- Data Source
  KAKENHI-PROJECT-20K21474
[Presentation] Transporter-mediated Regulation and Drug Interaction of Serum Uric Acid2021
- Author(s)
  Ikumi Tamai
- Organizer
  Forbidden City International Pharmacist Conference 2021 China
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02641
[Presentation] Constipation-relieving effect of apple due to down-regulation of ASBT2021
- Author(s)
  Qiunan Zhu, Takehiro Okaguchi, Ryusuke Iwai, Hisakazu Komori, Yoshiyuki Shirasaka, Ikumi Tamai
- Organizer
  日本薬物動態学会第36回年会
- Data Source
  KAKENHI-PROJECT-20K21474
[Presentation] セロトニン動態/腸内細菌叢の因果解析に基づく薬物性消化器毒性発現機構の定量的解明2021
- Author(s)
  関裕太、白坂善之、鮒井悠汰、浅地英、玉井郁巳
- Organizer
  第15回次世代を担う若手医療薬科学シンポジウム
- Data Source
  KAKENHI-PROJECT-20K07165
[Presentation] Mechanistic analysis of drug-induced gastrointestinal toxicity caused by altered disposition of serotonin2021
- Author(s)
  uta Funai, Yoshiyuki Shirasaka, Yuta Seki, Suguru Asaji, Ikumi Tamai
- Organizer
  日本薬物動態学会第36回年会
- Data Source
  KAKENHI-PROJECT-20K07165
[Presentation] セロトニン動態変動に起因した薬物性消化器毒性の発現機構解析2021
- Author(s)
  鮒井悠汰、白坂善之、関裕太、玉井郁巳
- Organizer
  日本薬剤学会第36年会
- Data Source
  KAKENHI-PROJECT-20K07165
[Presentation] Down-regulation of OATP2B1/SLCO2B1 Expression by MicroRNAs in Apple-derived Nanoparticles2021
- Author(s)
  Hisakazu Komori, Daichi Fujita, Yuma Shirasaki, Mayumi Arai,Qiunan Zhu, Ikumi Tamai
- Organizer
  日本薬物動態学会第36回年会
- Data Source
  KAKENHI-PROJECT-20K21474
[Presentation] A novel fluorescence-based method to evaluate the ileal apical sodium-dependent bile acid transporter ASBT2020
- Author(s)
  Qiunan Zhu, Hisakazu Komori, Rikako Imamura, Ikumi Tamai
- Organizer
  トランスポーター研究会、関東
- Data Source
  KAKENHI-PROJECT-20K21474
[Presentation] Regulation of intestinal OATP2B1 by food-derived microRNA through apple nanoparticles2019
- Author(s)
  Ikumi Tamai, Daichi Fujita, Hisakazu Komori
- Organizer
  BioMedical Transporter 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05111
[Presentation] DDI・DFIによるOATP2B1の活性変動機構の多様性2019
- Author(s)
  藤田大地、荒井まゆみ、朱秋楠、小森久和、玉井郁巳
- Organizer
  第41回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-16H05111
[Presentation] Regulation of intestinal OATP2B1 by microRNA contained in apple-derived nanoparticle as cargo.2019
- Author(s)
  Fujita D, Shirasaki S, Komori H, Tamai I.
- Organizer
  第34回日本薬物動態学会年会
- Data Source
  KAKENHI-PROJECT-16H05111
[Presentation] Food Effect on Intestinal Transporters ASBT and OATP2B1.2019
- Author(s)
  Tamai I.
- Organizer
  Meet the Experts: Transporter Conference Seoul 2019,
- Data Source
  KAKENHI-PROJECT-16H05111
[Presentation] Regulatory effect of fruit-derived nanoparticle on intestinal transporters organic anion transporting polypeptide (OATP) 2B12019
- Author(s)
  Fujita D, Komori H, Shirasaki Y, Arai T, Iwamoto Y, Wakayama T, Nakanishi T, Tamai I
- Organizer
  ISEV2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05111
[Presentation] Laxative effect of apple through modulation of intestinal bile acid transporter ASBT.2019
- Author(s)
  2)Iwamoto Y, Iwai R, Fujita D, Zhu Q, Aosaki H, Komori H, Tamai I.
- Organizer
  第34回日本薬物動態学会年会
- Data Source
  KAKENHI-PROJECT-16H05111
[Presentation] Drug-Drug and Drug-Food Interactions on Transporters2018
- Author(s)
  Tamai I
- Organizer
  CPSA Shanghai 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05111
[Presentation] トランスポーター～医薬品の作用・動態～2018
- Author(s)
  玉井郁巳
- Organizer
  石川県病院薬剤師会学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-16H05111
[Presentation] Introduction: ADME-PK Studies for Improved Prediction and Development of Oral Drug Products.2018
- Author(s)
  Tamai I
- Organizer
  2018 International Meeting on 22nd MDO and 33rd JSSX
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05111
[Presentation] Mechanisms and Impact of Drug-Drug and Drug-Food Interaction on Transporters2018
- Author(s)
  Tamai I
- Organizer
  The 3rd Drug Transporter Forum
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05111
[Presentation] 高尿酸血症が及ぼす薬物トランスポーター発現ならびに薬物動態変動2018
- Author(s)
  西澤　慧、依田典朗、諸角芙美、表　早紀、荒川　大、中西猛夫、玉井郁巳
- Organizer
  第3回北陸高尿酸血症セミナー
- Data Source
  KAKENHI-PROJECT-16H05111
[Presentation] 果物由来ナノ粒子が及ぼす小腸輸送体への影響2018
- Author(s)
  藤田大地、荒井俊樹、白崎佑磨、岩本結、小森久和、中西猛夫、玉井郁巳
- Organizer
  第33回人約z学会年会
- Data Source
  KAKENHI-PROJECT-16H05111
[Presentation] Drug-Drug and Drug-Food Interaction on Transporters2018
- Author(s)
  Ikumi Tamai
- Organizer
  CPSA Shanghai 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15158
[Presentation] Mechanism and Impact of Drug-Drug and Drug-Food Interactions on Transporters2018
- Author(s)
  Ikumi Tamai
- Organizer
  3rd Drug Transporter International Forum
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05111
[Presentation] Regulatory Effect of Fruit-derived Nanoparticle on Intestinal Transporters2018
- Author(s)
  Daichi Fujita, Toshiki Arai, Yuma Shirasaki, Yui Iwamoto, Hisakazu Komori, Takeo Nakanishi, Ikumi Tamai
- Organizer
  Experimental Biology 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15158
[Presentation] 薬物吸収とトランスポーター2018
- Author(s)
  玉井郁巳
- Organizer
  第35回　日本TDM学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-16H05111
[Presentation] Down regulation of intestinal bile acid transporter ASBT by apple-derived nanoparticles2018
- Author(s)
  Iwamoto Y, Fujita D, Arai T, Shirasaki　Y, Aosaki　H, Arai　M,　Wakayama T, Komori H, Nakanishi T, Tamaia I
- Organizer
  2018 International Meeting on 22nd MDO and 33rd JSSX
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05111
[Presentation] Drug-Drug and Drug-Food Interaction on Transporters2018
- Author(s)
  Ikumi Tamai
- Organizer
  CPSA Shanghai 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05111
[Presentation] 薬物吸収とトランスポーター2018
- Author(s)
  玉井郁巳
- Organizer
  日本TDM学会
- Invited
- Data Source
  KAKENHI-PROJECT-16H05111
[Presentation] Regulatory Effect of Fruit-derived Nanoparticle on Intestinal Transporters2018
- Author(s)
  Arai T, Shirasaki Y, Komori H, Nakanishi T, Tamai I
- Organizer
  EB2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05111
[Presentation] Regulatory Effect of Fruit-derived Nanoparticle on Intestinal Transporters2018
- Author(s)
  Daichi Fujita, Toshiki Arai, Yuma Shirasaki, Yui Iwamoto, Hisamazu Komori, Takeo Nakanishi, Ikumi Tamai
- Organizer
  Experimental Biology 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05111
[Presentation] Mechanism and Impact of Drug-Drug and Drug-Food Interactions on Transporters2018
- Author(s)
  Ikumi Tamai
- Organizer
  3rd Drug Transporter International Forum
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15158
[Presentation] 薬物吸収とトランスポーター2018
- Author(s)
  玉井郁巳
- Organizer
  日本TDM学会
- Invited
- Data Source
  KAKENHI-PROJECT-16K15158
[Presentation] Food-Drug and Drug-Drug Interactions2017
- Author(s)
  Ikumi Tamai
- Organizer
  Meet the Expert, Transporter Conference, 2017
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15158
[Presentation] 果物由来ナノ粒子が及ぼす小腸輸送体への影響2017
- Author(s)
  荒井俊樹、白崎佑磨、小森久和、中西猛夫、玉井郁巳
- Organizer
  日本薬学会年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-16K15158
[Presentation] Effect of Fruit-derived nanoparticle on intestinal transporters2017
- Author(s)
  Toshiki Arai, Yuma Shirasaki, Daichi Fujita, Takeo Nakanishi, Ikumi Tamai
- Organizer
  第32回日本薬物動態学会年会
- Data Source
  KAKENHI-PROJECT-16K15158
[Presentation] Food-Drug and Drug-Drug Interactions2017
- Author(s)
  Ikumi Tamai
- Organizer
  Meet the Expert, Transporter Conference, 2017
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05111
[Presentation] Effect of Fruit-derived nanoparticle on intestinal transporters2017
- Author(s)
  Toshiki Arai, Yuma Shirasaki, Daichi Fujita, Takeo Nakanishi, Ikumi Tamai
- Organizer
  第32回日本薬物動態学会年会
- Data Source
  KAKENHI-PROJECT-16H05111
[Presentation] Involvement of intestinal transporter OATP2B1 in gastrointestinal toxicity induced by SN-38, an active metabolite of anticancer irinotecan.2016
- Author(s)
  Fujita D, Nakanishi T, Tamai I
- Organizer
  The Globalization Pharmaceutics Education Network(GPEN) 2016
- Place of Presentation
  Lawrence, Kansas, USA
- Year and Date
  2016-11-09
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05111
[Presentation] 食品による薬物の消化管動態影響因子の活性変動の評価2016
- Author(s)
  Miki Y, Nakanishi T, Tamai I
- Organizer
  日本薬物動態学会第31回年会
- Place of Presentation
  松本
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-16H05111
[Presentation] トランスポーターでわかってきた薬物動態と生理機構2016
- Author(s)
  玉井郁巳
- Organizer
  日本薬物動態学会第31年会
- Place of Presentation
  松本
- Year and Date
  2016-10-13
- Invited
- Data Source
  KAKENHI-PROJECT-16H05111
[Presentation] Drug-Food Interaction and Evaluation2016
- Author(s)
  玉井郁巳
- Organizer
  日本薬物動態学会第31年会
- Place of Presentation
  松本市
- Year and Date
  2016-10-13
- Invited
- Data Source
  KAKENHI-PROJECT-16H05111
[Presentation] Risk and Benefit of Local DDI on Transporters2015
- Author(s)
  玉井郁巳
- Organizer
  日本薬剤学会　経口吸収フォーカスグループ第6回合宿討論会
- Place of Presentation
  金沢
- Year and Date
  2015-12-11
- Invited
- Data Source
  KAKENHI-PROJECT-26670075
[Presentation] Time to Consider Local DDI on Transporters2015
- Author(s)
  Ikumi Tamai,
- Organizer
  Seminar at University of Manchester, UK
- Place of Presentation
  Manchester, UK
- Year and Date
  2015-12-16
- Invited
- Data Source
  KAKENHI-PROJECT-26670075
[Presentation] Local DDI on Transporters2015
- Author(s)
  IkumiTamai
- Organizer
  TRIUMPH Symposium, Transporter-mediated Drug-Drug Interaction
- Place of Presentation
  東京
- Year and Date
  2015-07-08
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670075
[Presentation] ABC輸送体上での薬物相互作用に起因するDonepezilの心毒性リスク2015
- Author(s)
  Takeuchi R, Shinozaki K, Nakanishi T, Tamai I.
- Organizer
  日本薬剤学会第30年会
- Place of Presentation
  長崎
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26670075
[Presentation] 輸送体上での薬物間相互作用に起因するドネペジルの心毒性2014
- Author(s)
  竹内僚太、篠崎幸喜、玉井郁巳
- Organizer
  日本薬学会北陸支部第126回例会
- Place of Presentation
  金沢大学
- Year and Date
  2014-11-16
- Data Source
  KAKENHI-PROJECT-26670075
[Presentation] Cardiotoxicity of donepezil due to the drug-drug interaction on the efflux transporter in the heart2014
- Author(s)
  Takeuchi R. Tamai I
- Organizer
  The Globalization of Pharmaceutics Education Network (GPEN)
- Place of Presentation
  Helsinki, Finland
- Year and Date
  2014-08-28
- Data Source
  KAKENHI-PROJECT-26670075
[Presentation] 血管内皮細胞における尿酸輸送体を介した酸化ストレス調節2013
- Author(s)
  小森久和,安西尚彦,中西猛夫,玉井郁巳
- Organizer
  第46回日本痛風・核酸代謝学会総会
- Place of Presentation
  京王プラザホテル
- Year and Date
  2013-02-14
- Data Source
  KAKENHI-PROJECT-24890073
[Presentation] アンドロゲン受容体陽性前立腺がん細胞の増殖におけるOATPの役割2013
- Author(s)
  中西猛夫、荒川大、玉井郁巳
- Organizer
  日本薬学会医療薬科学部会　次世代を担う若手医療薬科学シンポジウム
- Place of Presentation
  仙台
- Invited
- Data Source
  KAKENHI-PROJECT-23590176
[Presentation] A possible enhanced effect of coffee constituents on intestinal urate excretion via BCRP2013
- Author(s)
  生川幸司、小森久和、中西猛夫、玉井郁巳
- Organizer
  日本薬物動態学会第28回年会
- Place of Presentation
  タワーホール船堀（東京）
- Data Source
  KAKENHI-PROJECT-24890073
[Presentation] A possible enhanced effect of coffee constituents on intestinal urate excretion via BCRP2013
- Author(s)
  生川幸司,小森久和,中西猛夫,玉井郁巳
- Organizer
  日本薬物動態学会第28年会
- Place of Presentation
  タワーホール船堀
- Year and Date
  2013-10-09
- Data Source
  KAKENHI-PROJECT-24890073
[Presentation] Negative transcriptional regulation of organic anion transporting polypeptide (OATP) 1A2 in androgen receptor (AR)-positive prostate cancer cells2013
- Author(s)
  柳原千泰、中西猛夫、西本朋弘、早川人希、玉井郁巳
- Organizer
  日本薬物動態学会第28年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590176
[Presentation] 血管内皮細胞障害への尿酸輸送体の関与2013
- Author(s)
  小森久和,安西尚彦,中西猛夫,玉井郁巳
- Organizer
  第23回北陸尿酸談話会
- Place of Presentation
  KKRホテル金沢
- Year and Date
  2013-03-02
- Data Source
  KAKENHI-PROJECT-24890073
[Presentation] Involvement of renal reabsorptive transporters in insulin-dependent increase of serum uric acid2013
- Author(s)
  小森久和,大箭考平,中西猛夫,玉井郁巳
- Organizer
  日本薬物動態学会第28年会
- Place of Presentation
  タワーホール船堀
- Year and Date
  2013-10-09
- Data Source
  KAKENHI-PROJECT-24890073
[Presentation] Involvement of renal reabsorptive transporters in insulin-dependent increase of serum uric acid2013
- Author(s)
  小森久和、大箭考平、中西猛夫、玉井郁巳
- Organizer
  日本薬物動態学会第28回年会
- Place of Presentation
  タワーホール船堀（東京）
- Data Source
  KAKENHI-PROJECT-24890073
[Presentation] Effect of drugs on renal urate reabsorption : evaluation by URAT1/URATv1 co-expressing cells2012
- Author(s)
  大箭考平,中西猛夫,小森久和,玉井郁巳
- Organizer
  日本薬物動態学会第27年会
- Place of Presentation
  タワーホール船堀
- Year and Date
  2012-11-20
- Data Source
  KAKENHI-PROJECT-24890073
[Presentation] Long-Lasting Effect of Fruit Juice on Intestinal Absorptive Transporter OATP2B12012
- Author(s)
  Yukiko Murata, Megumi Shichiri, Takanori Mori, Yoshiyuki Shirasaka, Takeo Nakanishi and Ikumi Tamai
- Organizer
  第26回日本薬物動態学会年会
- Place of Presentation
  タワーホール船橋/千葉
- Year and Date
  2012-11-21
- Data Source
  KAKENHI-PROJECT-23590175
[Presentation] In vitro evidence for functional interplay of SMCT1 and URAT1 for renal reabsorption of urate2012
- Author(s)
  盧楊,中西猛夫,小森久和,玉井郁巳
- Organizer
  日本薬物動態学会第27年会
- Place of Presentation
  タワーホール船堀
- Year and Date
  2012-11-20
- Data Source
  KAKENHI-PROJECT-24890073
[Presentation] Intestinal Transporters for oral Delivery and Detoxification2012
- Author(s)
  Ikumi Tamai
- Organizer
  International Symposium on PPF Molecular Pharmacokinetics Luncheon Seminar
- Place of Presentation
  一ツ橋ホール(東京都)
- Year and Date
  2012-01-17
- Data Source
  KAKENHI-PROJECT-21390044
[Presentation] Analysis of Drug Interaction on Bile Canalicular Transporters. International Symposium on PPF Molecular Pharmacokinetics2012
- Author(s)
  Ikumi Tamai
- Place of Presentation
  Hitotsubashi-Hall, Tokyo, Japan
- Year and Date
  2012-01-17
- Data Source
  KAKENHI-PROJECT-23659076
[Presentation] Intestinal Transporters for oral Delivery and Detoxification2012
- Author(s)
  Ikumi Tamai
- Organizer
  International Symposium on PPF Molecular Pharmacokinetics Luncheon Seminar
- Place of Presentation
  一ツ橋ホール(東京都)(招待講演)
- Year and Date
  2012-01-17
- Data Source
  KAKENHI-PROJECT-21390044
[Presentation] A Role of Prostaglandin Transporter in Regulating PGE2 Release from Human Bronchial BEAS-2B Cells under Inflammatory Conditions2012
- Author(s)
  Yoshiyuki Shirasaka, Takeo Nakanishi, Taku Kasai, Megumi Scichiri, Kazuyuki Hayashi, Akio Nishiura, and Ikumi Tamai
- Organizer
  第26回日本薬物動態学会年会
- Place of Presentation
  タワーホール船橋/千葉
- Year and Date
  2012-11-21
- Data Source
  KAKENHI-PROJECT-23590175
[Presentation] α1-acid glycoprotein exerts protective effect against hemolysis-induced oxidative stress via the enhancement of CD163 expression2012
- Author(s)
  小森久和,渡邊博志,首藤剛,小玉あずさ,甲斐博文,小田切優樹,玉井郁巳,丸山徹
- Organizer
  日本薬物動態学会第27年会
- Place of Presentation
  タワーホール船堀
- Year and Date
  2012-11-20
- Data Source
  KAKENHI-PROJECT-24890073
[Presentation] Substrate-Dependent Drug-Grapefruit Juice Interactions Caused by Multiple Binding Sites on OATP2B12012
- Author(s)
  Takanori Mori, Yoshiyuki Shirasaka, Yukiko Murata, Takeo Nakanishi and Ikumi Tamai
- Organizer
  第26回日本薬物動態学会年会
- Place of Presentation
  タワーホール船橋/千葉
- Year and Date
  2012-11-21
- Data Source
  KAKENHI-PROJECT-23590175
[Presentation] Interplay and difference of transporters and enzymes in drug absorption, disposition and action2012
- Author(s)
  Ikumi Tamai
- Organizer
  50thAnniversary Symposium on Cytochrome P450 in Fukuoka
- Place of Presentation
  Kyushu University, Fukuoka, Japan.
- Year and Date
  2012-12-02
- Data Source
  KAKENHI-PROJECT-23659076
[Presentation] Application ofquantitative time-lapse imaging (QTLI)for evaluation of MRP2/MRP2-baseddrug-drug interaction in rat andhuman hepatocytes2012
- Author(s)
  Ikumi Tamai
- Organizer
  The 27thJSSX Annual Meeting
- Place of Presentation
  タワーホール船堀,東京
- Year and Date
  2012-11-20
- Data Source
  KAKENHI-PROJECT-23659076
[Presentation] 消化管膜機能制御に基づく抗糖尿病作用を有する配糖体-高分子複合体の精密設計2012
- Author(s)
  佐久間信至, 金光俊, 寺岡裕美, 政岡祥江, 片岡誠, 山下伸二, 白坂善之, 玉井郁巳, 村岡雅弘, 中辻洋司, 木田敏之, 明石満
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-21590051
[Presentation] Transport Mechanism of Trans-1-amino-3-F^<18>-fluorocyclobutanecarboxylic Acid(F^<18>-FACBC) in Human Prostate Cancer2012
- Author(s)
  Okudaira H., Shikano N., Nishii R., Miyagi T., Yoshimoto M., Kobayashi M., Ohe K., Nakanishi T., Namiki M., Tamai I., Kawai K
- Organizer
  International Symposium on Past, Present and Future of Molecular Pharmacokinetics
- Place of Presentation
  University of Tokyo(Japan)
- Year and Date
  2012-01-16
- Data Source
  KAKENHI-PROJECT-21659286
[Presentation] OATP transporters is involved in intestinal absorption of urate2012
- Author(s)
  生川幸司,御勢智香,小森久和,中西猛夫,玉井郁巳
- Organizer
  日本薬物動態学会第27年会
- Place of Presentation
  タワーホール船堀
- Year and Date
  2012-11-20
- Data Source
  KAKENHI-PROJECT-24890073
[Presentation] 前立腺癌細胞におけるトランスポーターを介したアンドロゲン供給調節機構の解明2012
- Author(s)
  西本朋弘、中西猛夫、柳原千泰、荒川大、玉井郁巳
- Organizer
  日本薬剤学会第27年会
- Place of Presentation
  神戸国際会議場（兵庫県）
- Data Source
  KAKENHI-PROJECT-23590176
[Presentation] Mechanism and Interaction of Absorptive Drug Transporters2011
- Author(s)
  Ikumi Tamai
- Organizer
  4^<th> Asia Pacific Regional Meeting of ISSX
- Place of Presentation
  台湾
- Year and Date
  2011-04-23
- Data Source
  KAKENHI-PROJECT-21390044
[Presentation] 腎・肝トランスポーターの生理機能を反映させた薬物影響評価系の構築2011
- Author(s)
  Ikumi Tamai
- Organizer
  第38回日本トキシコロジ-学会学術年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2011-07-13
- Data Source
  KAKENHI-PROJECT-21390044
[Presentation] FUNCTIONAL PLEIOTROPY OF OATP2B1 DUE TO MULTIPLE BINDING SITES2011
- Author(s)
  Yoshiyuki Shirasaka, Takanori Mori, Megumi Shichiri, Satoshi Koyama, Yukiko Murata, Yusuke Hoshino, Takeo Nakanishi and Ikumi Tamai
- Organizer
  第26回日本薬物動態学会
- Place of Presentation
  広島国際会議場（広島県）
- Data Source
  KAKENHI-PROJECT-23590175
[Presentation] シンポジウム「痛風・高尿酸血症:最近の進歩」医薬品による血中尿酸値制御2011
- Author(s)
  玉井郁巳
- Organizer
  日本薬学会第131年会
- Place of Presentation
  東日本大震災のため誌上開催招待講演
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-21390044
[Presentation] シンポジウム「痛風・高尿酸血症:最近の進歩」医薬品による血中尿酸値制御2011
- Author(s)
  玉井郁巳
- Organizer
  日本薬学会第131年会
- Place of Presentation
  ツインメッセ静岡(静岡県)
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-21390044
[Presentation] デンドリマー型アルブチンの化学構造とSGLT1(Na+/糖共輸送体)の阻害活性との相関の検証2011
- Author(s)
  金光俊, 佐久間信至, 寺岡裕美, 政岡祥江, 片岡誠, 山下伸二, 白坂善之, 玉井郁巳, 村岡雅弘, 中辻洋司, 木田敏之, 明石満
- Organizer
  第27回日本DDS学会
- Place of Presentation
  東京
- Year and Date
  2011-06-09
- Data Source
  KAKENHI-PROJECT-21590051
[Presentation] Variability of Fruit Juice-Drug Interaction in Absorption Process Caused by Multiple Binding Sites on OATP2B12011
- Author(s)
  Takanori Mori, Yoshiyuki Shirasaka, Megumi Shichiri, Satoshi Koyama, Yukiko Murata, Yusuke Hoshino, Takeo Nakanishi, and Ikumi Tamai
- Organizer
  第26回日本薬物動態学会年会
- Place of Presentation
  広島国際会議場/広島
- Year and Date
  2011-11-16
- Data Source
  KAKENHI-PROJECT-23590175
[Presentation] 腎・肝トランスポーターの生理機能を反映させた薬物影響評価系の構築2011
- Author(s)
  Ikumi Tamai
- Organizer
  第38回日本トキシコロジー学会学術年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2011-07-13
- Data Source
  KAKENHI-PROJECT-21390044
[Presentation] In vitro蛍光イメージング(QTLI)法を用いたMRP2機能変動評価－肝代謝を考慮した薬物間相互作用予測への応用－2011
- Author(s)
  池永美穂、中西猛夫、福田元、白坂善之、玉井郁巳
- Organizer
  日本薬学会北支部第123回例会
- Place of Presentation
  金沢大学
- Data Source
  KAKENHI-PROJECT-23659076
[Presentation] Functional Pleiotropy of OATP2B1 Due to Multiple Binding Sites2011
- Author(s)
  Yoshiyuki Shirasaka, Takanori Mori, Megumi Shichiri, Satoshi Koyama, Yukiko Murata, Yusuke Hoshino, Takeo Nakanishi, and Ikumi Tamai
- Organizer
  第26回日本薬物動態学会年会
- Place of Presentation
  広島国際会議場/広島
- Year and Date
  2011-11-16
- Data Source
  KAKENHI-PROJECT-23590175
[Presentation] Attenuation of Oral Absorption of P-glycoprotein Substrate Drugs by Administrating in Controlled-Release Formulation2011
- Author(s)
  Yoshiyuki Shirasaka, Takeo Nakanishi, Peter Langguth, and Ikumi Tamai
- Organizer
  International Symposium on BA/BE of Oral Drug Products
- Place of Presentation
  Kobe International Conference Center/Kobe, Japan
- Year and Date
  2011-06-30
- Data Source
  KAKENHI-PROJECT-23590175
[Presentation] Intestinal OATP Transporters as Target for Drug Absorption and Interaction2011
- Author(s)
  Ikumi Tamai
- Organizer
  AAPS Annual Meeting, Round Table Discussion
- Place of Presentation
  Water E.Washington Convention Center Washington DC,(米国)
- Year and Date
  2011-10-25
- Data Source
  KAKENHI-PROJECT-21390044
[Presentation] P-gpを介した薬物吸収動態解析に基づいた徐放性製剤設計の最適化2011
- Author(s)
  白坂善之、Peter Langguth、中西猛夫、玉井郁巳
- Organizer
  日本薬剤学会第26年会
- Place of Presentation
  タワーホール船堀（東京都）
- Data Source
  KAKENHI-PROJECT-23590175
[Presentation] Extra-Renal Excretion of Uric Acid in Rats2011
- Author(s)
  Atsushi Hosomi, Takeo Nakanishi, Ikumi Tamai
- Organizer
  14th International Symposium on Purine and Pyrimidme Metabolism in Man
- Place of Presentation
  京王プラザホテル(東京都)
- Year and Date
  2011-02-21
- Data Source
  KAKENHI-PROJECT-21390044
[Presentation] 薬物間相互作用間相互作用の予測:薬物吸収過程における薬物間相互作用取り込みトランスポーター2011
- Author(s)
  Ikumi Tamai
- Organizer
  CBI学会研究会
- Place of Presentation
  東京大学薬学系総合研究棟講堂(東京都)
- Year and Date
  2011-12-05
- Data Source
  KAKENHI-PROJECT-21390044
[Presentation] Drug Absorption and Interaction on Intestinal Influx/Uptake Transporters2011
- Author(s)
  Ikumi Tamai
- Organizer
  26^<th> JSSX Annual Meeting
- Place of Presentation
  広島国際会議場(広島県)
- Year and Date
  2011-11-18
- Data Source
  KAKENHI-PROJECT-21390044
[Presentation] Role of Absorptive Transporter : Impact on Oral BA and DDI2011
- Author(s)
  Ikumi Tamai
- Organizer
  International Symposium on BA/BE of Oral Drug Products
- Place of Presentation
  神戸コンベンションセンター(兵庫県)
- Year and Date
  2011-06-29
- Data Source
  KAKENHI-PROJECT-21390044
[Presentation] Drug Absorption and Interaction on Intestinal Transporters2011
- Author(s)
  Ikumi Tamai, Yoshiyuki Shirasaka, and Takeo Nakanishi
- Organizer
  第26回日本薬物動態学会年会
- Place of Presentation
  広島国際会議場/広島
- Year and Date
  2011-11-16
- Data Source
  KAKENHI-PROJECT-23590175
[Presentation] 高分子と生体膜の相互作用を利用した新たな治療戦略2011
- Author(s)
  Ikumi Tamai
- Organizer
  日本膜学会第33年会シンポジウム
- Place of Presentation
  産業技術総合研究所(東京都)
- Year and Date
  2011-05-13
- Data Source
  KAKENHI-PROJECT-21390044
[Presentation] Upregulation of organic anion transporting polypeptides (OATPs) under the androgen-depletion conditions; A possible molecular mechanism for castration resistance in prostate cancer.2011
- Author(s)
  荒川大、中西猛夫、白坂義之、玉井郁巳
- Organizer
  日本薬物動態学会第26年会
- Place of Presentation
  広島国際会議場（広島県）
- Data Source
  KAKENHI-PROJECT-23590176
[Presentation] Inhibitory effect of arbutin conjugated to polyamidoamine dendrimers on intestinal glucose transport2011
- Author(s)
  Shun Kanamitsu, Shinji Sakuma, Yumi Teraoka, Yoshie Masaoka, Makoto Kataoka, Shinji Yamashita, Yoshiyuki Shirasaka, Ikumi Tamai, Masahiro Muraoka, Yohji Nakatsuji, Toshiyuki Kida, Mitsuru Akashi
- Organizer
  International Symposium on BA/BE of Oral Drug Products
- Place of Presentation
  Kobe, Japan
- Year and Date
  2011-06-30
- Data Source
  KAKENHI-PROJECT-21590051
[Presentation] VARIABILITY OF FRUIT JUICE-DRUG INTERACTION IN ABSORPTION PROCESS CAUSED BY MULTIPLE BINDING SITES ON OATP2B12011
- Author(s)
  Takanori Mori, Yoshiyuki Shirasaka, Megumi Shichiri, Satoshi Koyama, Yukiko Murata, Yusuke Hoshino, Takeo Nakanishi and Ikumi Tamai
- Organizer
  第26回日本薬物動態学会
- Place of Presentation
  広島国際会議場（広島県）
- Data Source
  KAKENHI-PROJECT-23590175
[Presentation] Attenuation of Oral Absorption of P-glycoprotein Substrate Drugs by Administrating in Controlled-Release Formulation2011
- Author(s)
  Yoshiyuki Shirasaka, Takeo Nakanishi, Peter Langguth, and Ikumi Tamai
- Organizer
  International Symposium on BA/BE of Oral Drug Products
- Place of Presentation
  Kobe International Conference Center（兵庫県）
- Data Source
  KAKENHI-PROJECT-23590175
[Presentation] P-gpを介した薬物吸収動態解析に基づいた徐放性製剤設計の最適化2011
- Author(s)
  白坂善之、Peter Langguth、中西猛夫、玉井郁巳
- Organizer
  日本薬剤学会第26年会
- Place of Presentation
  タワーホール船堀/東京
- Year and Date
  2011-05-29
- Data Source
  KAKENHI-PROJECT-23590175
[Presentation] 消化管に発現する薬物トランスポーターと薬効・毒性2011
- Author(s)
  Ikumi Tamai
- Organizer
  第18回HAB研究機構学術年会シンポジウム
- Place of Presentation
  昭和大学上条講堂(東京都)
- Year and Date
  2011-05-20
- Data Source
  KAKENHI-PROJECT-21390044
[Presentation] Intestinal OATPT ransporters as Target for Drug Absorption and Interaction, AAPS Annual Meeting2011
- Author(s)
  Ikumi Tamai
- Organizer
  Round Table Discussion
- Place of Presentation
  Water E. Washington Convention Center(USA)
- Year and Date
  2011-10-25
- Data Source
  KAKENHI-PROJECT-21390044
[Presentation] Differential Interaction of Fruit Juices with Transporter-Mediated Absorption of Drugs2011
- Author(s)
  Megumi Shichiri, Yoshiyuki Shirasaka, Takanori Mori, Takeo Nakanishi, and Ikumi Tamai
- Organizer
  The 4th Asian Pacific ISSX Regional Meeting
- Place of Presentation
  Tainan, Taiwan
- Year and Date
  2011-04-24
- Data Source
  KAKENHI-PROJECT-23590175
[Presentation] Mechanism and Interaction of Absorptive Drug Transporters2011
- Author(s)
  Ikumi Tamai
- Organizer
  4^<th> Asia Pacific Regional Meeting of ISSX
- Place of Presentation
  国立成功大学(台湾)
- Year and Date
  2011-04-23
- Data Source
  KAKENHI-PROJECT-21390044
[Presentation] DRUG ABSORPTION AND INTERACTION ON INTESTINAL TRANSPORTERS2011
- Author(s)
  Ikumi Tamai, Yoshiyuki Shirasaka, Takeo Nakanishi
- Organizer
  第26回日本薬物動態学会
- Place of Presentation
  広島国際会議場（広島県）
- Data Source
  KAKENHI-PROJECT-23590175
[Presentation] Upregulation of organic anion transporting polypeptides (OATPs) under the androgen-depletion conditions; A possible molecular mechanism for castration resistance in prostate cancer.2011
- Author(s)
  荒川大、中西猛夫、白坂義之、玉井郁巳
- Organizer
  日本薬物動態学会第26年会
- Place of Presentation
  広島国際会議場（広島）
- Data Source
  KAKENHI-PROJECT-23590176
[Presentation] シンポジウム「小腸上皮細胞の機能特性を利用した医薬品吸収促進戦略」Influx/Effluxトランスポーターによる薬物の消化管吸収制御機構2011
- Author(s)
  白坂善之、中西猛夫、玉井郁巳
- Organizer
  日本薬学会第131年会
- Place of Presentation
  東日本大震災のため誌上開催
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-21659038
[Presentation] In vitro蛍光イメージング(QTL1)法を用いたMRP2機能変動評価-肝代謝を考慮した薬物間相互作用予測への応用-2011
- Author(s)
  Ikumi Tamai
- Organizer
  日本薬学会北陸支部第123回例会
- Place of Presentation
  金沢大学(石川県)
- Year and Date
  2011-11-27
- Data Source
  KAKENHI-PROJECT-23659076
[Presentation] 消化管における取り込みトランスポーターと排出トランスポーターの協関2011
- Author(s)
  Ikumi Tamai
- Organizer
  創剤フォーラム第17回シンポジウム
- Place of Presentation
  アルカディア市ヶ谷(東京都)
- Year and Date
  2011-09-30
- Data Source
  KAKENHI-PROJECT-21390044
[Presentation] QUANTITATIVE VISUALIZATION OF LIVER BILE CANALICULAR TRANSPORTER ACTIVITY BY TIME-LAPSE IMAGING TO EVALUATEDRUG-DRUG INTERACTION IN SANDWICH-CULTURED HEPATOCYTES2010
- Author(s)
  Ikumi Tamai, Yoko Fukuyama, Yuta Shibue, Takeo Nakanishi
- Organizer
  9TH INTERNATIONAL MEETING OF ISSX
- Place of Presentation
  Istanbul Lutfi Kirdar Convention and Exhibition Center-Harbiye、(トルコ)
- Year and Date
  2010-09-06
- Data Source
  KAKENHI-PROJECT-21659038
[Presentation] DIFFERENTIAL TRANSPORTER-MEDIATED INTBRACTION OF FRUITJUICE WITH INTESTINAL ABSORPTION OF PRAVASTATIN ANDPITAVASTATIN IN RATS2010
- Author(s)
  Yoshiyuki Shirasaka, Kensuke Suzuki, Takeo Nakanishi, Ikumi Tamai
- Organizer
  第25回日本薬物動態学会年会
- Place of Presentation
  大宮ソニックシティ(埼玉県)
- Year and Date
  2010-10-08
- Data Source
  KAKENHI-PROJECT-21659038
[Presentation] トランスポーターを介したHMG・CoA還元酵索阻害薬の消化IS吸収動態2010
- Author(s)
  白坂善之、鈴木健介、中西猛夫、玉井郁己
- Organizer
  第25回日本薬剤学会年会
- Place of Presentation
  あわぎんホール徳島県郷土文化会館(徳島県)
- Year and Date
  2010-05-12
- Data Source
  KAKENHI-PROJECT-21659038
[Presentation] 医薬品・食品の吸収動態と相互作用2010
- Author(s)
  玉井郁巳
- Organizer
  フードサイエンス棟竣工記念シンポジウム(招そ寺講演)
- Place of Presentation
  東京大学(東京都)
- Year and Date
  2010-12-11
- Data Source
  KAKENHI-PROJECT-21390044
[Presentation] 医薬品・食品の吸収動態と相互作用2010
- Author(s)
  玉井郁巳
- Organizer
  フードサイエンス棟竣工記念シンポジウム
- Place of Presentation
  東京大学(東京都)
- Year and Date
  2010-12-11
- Data Source
  KAKENHI-PROJECT-21390044
[Presentation] イプラトロピウムの気道吸収における有機カチオン/カルニチントランスポーターの関与2010
- Author(s)
  春田恒満、中西猛夫、長谷川佳駿、白坂善之、玉井郁巳
- Organizer
  日本薬学会北陸支部第122回例会
- Place of Presentation
  北陸大学(石川県)
- Year and Date
  2010-11-21
- Data Source
  KAKENHI-PROJECT-21659038
[Presentation] トランスポ-タ-と医薬品の作用・副作用2010
- Author(s)
  玉井郁巳
- Organizer
  応用トキシコロジー:リカレント講座
- Place of Presentation
  金沢大学サテライト・プラザ金沢市(石川県)
- Year and Date
  2010-09-30
- Data Source
  KAKENHI-PROJECT-21390044
[Presentation] Differential Interaction of Grapefruit Juice with Intestinal Absorption of HMG-CoA Reductase Inhibitors Pravastatin and Pitavastatin2010
- Author(s)
  Y.Shirasaka.K.Suzuki, T.Nakanishi.I.Tamai
- Organizer
  Globalization of Pharmaceutics Education Network (GPEN) Meeting
- Place of Presentation
  University of North Carolina(米国)
- Year and Date
  2010-11-11
- Data Source
  KAKENHI-PROJECT-21659038
[Presentation] サポートからリードへ:トランスポーターと創薬・医薬品開発2010
- Author(s)
  玉井郁巳
- Organizer
  第31回臨床薬理学会年会
- Place of Presentation
  国立京都国際会館(京都府) 招待講演
- Year and Date
  2010-12-03
- Data Source
  KAKENHI-PROJECT-21390044
[Presentation] Involvement and Interaction of Transporters in Intestinal and Pulmonary Absorption of Drugs.2010
- Author(s)
  Ikumi Tamai
- Organizer
  AAPS Annual Meeting, Symposium
- Place of Presentation
  Morial Convention Center(米国)(招待講演)
- Year and Date
  2010-11-18
- Data Source
  KAKENHI-PROJECT-21659038
[Presentation] ラットを用いた薬物による尿酸動態変動の評価2010
- Author(s)
  佐藤正延, 嶋田翔, 細見篤史, 中西猛夫, 玉井郁巳
- Organizer
  第43回痛風核酸代謝学会年会
- Place of Presentation
  大阪国際交流センター、(大阪市)
- Year and Date
  2010-02-26
- Data Source
  KAKENHI-PROJECT-21390044
[Presentation] トランスポーターと医薬品の作用・副作用2010
- Author(s)
  玉井郁巳
- Organizer
  応用トキシコロジー:リカレント講座
- Place of Presentation
  金沢大学サテライト・プラザ、(石川県)(招待講演)
- Year and Date
  2010-09-30
- Data Source
  KAKENHI-PROJECT-21659038
[Presentation] トランスポーターと医薬品の作用・副作用2010
- Author(s)
  玉井郁巳
- Organizer
  応用トキシコロジー:リカレント講座
- Place of Presentation
  金沢大学サテライト・プラザ(石川県) 招待講演
- Year and Date
  2010-09-30
- Data Source
  KAKENHI-PROJECT-21390044
[Presentation] Renal and Intestinal Transport and Interactions2010
- Author(s)
  Ikumi Tamai
- Organizer
  Globalization of Pharmaceutics Education Network(GPEN) Meeting
- Place of Presentation
  University of North Carolina(米国)
- Year and Date
  2010-11-11
- Data Source
  KAKENHI-PROJECT-21390044
[Presentation] DIFFFRENTIAL lNTERACTI0N OF FRUIT JUICES ON TRANSPORTIER-MLDIATED ABSORPTION OF DRUGS2010
- Author(s)
  Megumi Shichiri, Yoshiyuki Shirasaka, Takanori Mori, Takeo Nakanishi, Ikumi Tainai
- Organizer
  第25回日本薬物動態学会年会
- Place of Presentation
  大宮ソニックシティ(埼玉県)
- Year and Date
  2010-10-08
- Data Source
  KAKENHI-PROJECT-21659038
[Presentation] ヒト癌細胞株におけるOAT2を介した光線力学療法薬5・アミノレブリン酸の細胞膜輸送2010
- Author(s)
  小川哲朗、中西猛夫、白坂善之、長崎幸夫、松井裕史、玉井郁己
- Organizer
  第25回日本薬剤学会年会
- Place of Presentation
  あわぎんホール徳勧県郷土文化会館(徳島県)
- Year and Date
  2010-05-12
- Data Source
  KAKENHI-PROJECT-21659038
[Presentation] Uric Acid Transporter-Mediated Uricosuric Effect of RDEA594, A Metab olite of Antiviral Agent RDEA8062010
- Author(s)
  Mayuko Yoshifuji, Masanobu Sato, Li-Tain Yeh, Kohei Ohya, Yoshiyuki Shirasaka, Takeo Nakanishi, Ikumi Tamai
- Organizer
  Globalization of Pharmaceutics Education Network (GPEN) Meeting
- Place of Presentation
  University of North Carolina,チャペルヒル,NC,米国
- Year and Date
  2010-11-11
- Data Source
  KAKENHI-PROJECT-21390044
[Presentation] SYSTEM L AMINO ACID TRANSPORTER 1(LAT1)IS A POSSIBLE TARGET FOR COMBINATION THERAPY WITH ANTIPROLIFERATIVE AMINOPEPTIDASE INHIBITORS IN HUMAN OVARIAN CANCER A ND LUKEMIA CELLS2010
- Author(s)
  Takeo Nakanishi, Douglas, D Ross,Hiroshi Arakawa, Ikumi Tagmai
- Organizer
  第25回日本薬物動態学会年会
- Place of Presentation
  大宮ソニックシティ(埼玉県)
- Year and Date
  2010-10-08
- Data Source
  KAKENHI-PROJECT-21659038
[Presentation] ヒト癌細胞株におけるOAT2を介した光線力学療法薬5-アミノレブリン酸の細胞膜輸送2010
- Author(s)
  小川哲郎、中西猛夫、白坂善之、松井裕史、玉井郁巳
- Organizer
  日本薬剤学会第25年会
- Place of Presentation
  あわぎんホール徳島県強度文化会館(徳島市、徳島)
- Year and Date
  2010-05-14
- Data Source
  KAKENHI-PROJECT-21890084
[Presentation] COPD治療薬の体内動態におけるトランスポーターの役割2010
- Author(s)
  中西猛夫、春田恒満、長谷川佳駿、白坂善之、玉井郁己
- Organizer
  第32回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  富山国際会議場(富山県)
- Year and Date
  2010-11-29
- Data Source
  KAKENHI-PROJECT-21659038
[Presentation] 消化管吸収過程における薬物とミルクのペプチドトランスポーター(PEPT 1)を介した相互作用の解析2010
- Author(s)
  小林彰子、我妻瑤恵、森本かおり、叶隆、和田翔、白坂善之、玉井郁巳、荻原琢男
- Organizer
  第25回日本薬剤学会年会
- Place of Presentation
  あわぎんホール徳島県郷土文化会館(徳島県)
- Year and Date
  2010-05-12
- Data Source
  KAKENHI-PROJECT-21659038
[Presentation] TRACHEAL ABSORPTION OF AN ANTICHOLINERGIC BRONCHODI LATOR IPRATROPIUM VIA ORGANIC CATION TRANSPORTERS2010
- Author(s)
  Tsunemitsu Haruta, Takeo Nakanishi, Yoshitaka Hasegawa, Miho Ikenaga, Ikumi Tamai
- Organizer
  第25回日本薬鋤態学会年会
- Place of Presentation
  大宮ソニックシティ(埼玉県)
- Year and Date
  2010-10-08
- Data Source
  KAKENHI-PROJECT-21390044
[Presentation] DIFFERENTIAL EXPRESSION OF ORGANIC CATION TRANSPORTERS IN RAT DORSAL ROOT GANGLIA2010
- Author(s)
  Nancy N Jong, Johnson J Liu, Mark J McKeage, Takeo Nakanishi, Ikumi Tamai
- Organizer
  第25回日本薬物動態学会年会
- Place of Presentation
  大宮ソニックシティ(埼玉県)
- Year and Date
  2010-10-08
- Data Source
  KAKENHI-PROJECT-21659038
[Presentation] サポートからリードへ:トランスポ-タ-と創薬・医薬品開発2010
- Author(s)
  玉井郁巳
- Organizer
  第31回臨床薬理学会年会
- Place of Presentation
  国立京都国際会館(京都府)
- Year and Date
  2010-12-03
- Data Source
  KAKENHI-PROJECT-21390044
[Presentation] quantitative Visualization for Bile Canalicular transporter function using Sandwich・?culatured rat hepatocytes2010
- Author(s)
  Yoko Fukuyama, Takeo Nakanishi, Miho Ikenaga, Yoshiyuki Shirasaka, Ikumi Tamai
- Organizer
  第25回日本薬物動態学会年会
- Place of Presentation
  大宮ソニックシティ(埼玉県)
- Year and Date
  2010-10-08
- Data Source
  KAKENHI-PROJECT-21659038
[Presentation] Renal and Intestinal Transport and Interactions2010
- Author(s)
  Ikumi Tamai
- Organizer
  Globalization of Pharmaceutics Education Network (GPEN) Meeting
- Place of Presentation
  University of North Carolina,チャペルヒル,NC,米国招待講演
- Year and Date
  2010-11-11
- Data Source
  KAKENHI-PROJECT-21390044
[Presentation] Role of Intestinal and Hepatic OATPs in Drug Absorption and Disposition2009
- Author(s)
  玉井郁巳
- Organizer
  3^<rd> Asian-Pacific ISSX Meeting
- Place of Presentation
  インペリアルクイーンズパークホテル、バンコク市、(タイ)
- Year and Date
  2009-05-10
- Data Source
  KAKENHI-PROJECT-21390044
[Presentation] がんの診断と治療へのトランスポーター活性の利用2009
- Author(s)
  玉井郁巳
- Organizer
  日本医療薬学会年会
- Place of Presentation
  長崎医師会館、(長崎市)
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-21390044
[Presentation] Drug transporters as target for drug delivery and cancer therapy.2009
- Author(s)
  Nakannishi T., Tamai I.
- Organizer
  Asian Federation of Pharmaceutical Scientists
- Place of Presentation
  九州大学(福岡市)
- Year and Date
  2009-10-16
- Data Source
  KAKENHI-PROJECT-21659038
[Presentation] A Molecular Mechanism of Hepatic Uptake of γ-Butyrobetaine, a Precursor of Carnitine Biosynthesis2009
- Author(s)
  Fujita M., Nakanishi T., Shibue Y., Fukuyama Y., Shirasaka Y., Tamai I.
- Organizer
  生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  大阪大学(大阪)
- Data Source
  KAKENHI-PROJECT-21659038
[Presentation] 尿酸代謝に及ぼすARBの影響2009
- Author(s)
  玉井郁巳
- Organizer
  高血圧診療UpDate研究会
- Place of Presentation
  ホテル金沢 (金沢市)
- Year and Date
  2009-10-15
- Data Source
  KAKENHI-PROJECT-21390044
[Presentation] 医薬品の吸収にトランスポーターはどこまだ関わるか2009
- Author(s)
  玉井郁巳
- Organizer
  創薬薬理フォーラム第17回シンポジウム
- Place of Presentation
  長井記念館、(東京)
- Year and Date
  2009-09-10
- Data Source
  KAKENHI-PROJECT-21390044
[Presentation] ここまでわかってきた消化管吸収における薬物吸収分子機構薬物の吸収性を調節する消化管トランスポーター2009
- Author(s)
  玉井郁巳
- Organizer
  第28臨床薬理阿蘇九重カンファレンス
- Place of Presentation
  ハウステンボス(長崎県)
- Year and Date
  2009-07-18
- Data Source
  KAKENHI-PROJECT-21390044
[Presentation] がんの診断と治療へのトランスポーター活性の利用2009
- Author(s)
  玉井郁巳
- Organizer
  日本医療薬学会年会
- Place of Presentation
  長崎医師会館(長崎県)
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-21390044
[Presentation] 尿酸代謝に及ぼすARBの影響2009
- Author(s)
  玉井郁巳
- Organizer
  高血圧診療Up Date研究会
- Place of Presentation
  ホテル金沢(石川県)
- Year and Date
  2009-10-15
- Data Source
  KAKENHI-PROJECT-21390044
[Presentation] Transporters Involved in Uricosuric and Antiuricosuric Effects of Anti-hypertensives2009
- Author(s)
  Tamai I
- Organizer
  米国腎臓学会年会
- Place of Presentation
  サンジエゴコンベンションセンター(米国)
- Year and Date
  2009-10-30
- Data Source
  KAKENHI-PROJECT-21390044
[Presentation] Role of Intestinal and Hepatic OATPs in Drug Absorption and Disposition2009
- Author(s)
  Tamai I
- Organizer
  3^<rd> Asian-Pacific ISSX Meeting
- Place of Presentation
  インペリアルクイーンズパークホテル(タイ)
- Year and Date
  2009-05-10
- Data Source
  KAKENHI-PROJECT-21390044
[Presentation] TDMとトランスポーター研究2009
- Author(s)
  玉井郁巳
- Organizer
  日本TDM学会学術年会
- Place of Presentation
  新潟コンベンションセンター(新潟県)
- Year and Date
  2009-06-13
- Data Source
  KAKENHI-PROJECT-21390044
[Presentation] Role of Intestinal and Hepatic OATPs in Drug Absorption and Disposition.2009
- Author(s)
  玉井郁巳
- Organizer
  3^<rd> Asian-Pacific ISSX Meeting
- Place of Presentation
  インペリアルクイーンズパークホテル、バンコク市、(タイ)
- Year and Date
  2009-05-10
- Data Source
  KAKENHI-PROJECT-21659038
[Presentation] 医薬品の吸収にトランスポーターはどこまだ関わるか2009
- Author(s)
  玉井郁巳
- Organizer
  創薬薬理フォーラム第17回シンポジウム
- Place of Presentation
  長井記念館(東京都)
- Year and Date
  2009-09-10
- Data Source
  KAKENHI-PROJECT-21390044
[Presentation] 医薬品の吸収にトランスポーターはどこまだ関わるか2009
- Author(s)
  玉井郁巳
- Organizer
  創薬薬理フォーラム第17回シンポジウム
- Place of Presentation
  長井記念館(東京)
- Year and Date
  2009-09-10
- Data Source
  KAKENHI-PROJECT-21659038
[Presentation] Transporters Involved in Uricosuric and Antiuricosuric Effects of Anti-hypertensives2009
- Author(s)
  玉井郁巳, 佐藤正延
- Organizer
  米国腎臓学会年会
- Place of Presentation
  サンジエゴコンペンションセンター、サンジエゴ市、(米国)
- Year and Date
  2009-10-30
- Data Source
  KAKENHI-PROJECT-21390044
[Presentation] TDMとトランスポーター研究2009
- Author(s)
  玉井郁巳
- Organizer
  日本TDM学会学術年会
- Place of Presentation
  新潟コンベンションセンター、(新潟市)
- Year and Date
  2009-06-13
- Data Source
  KAKENHI-PROJECT-21390044
[Presentation] ここまでわかってきた消化管吸収における薬物吸収分子機構薬物の吸収性を調節する消化管トランスポーター2009
- Author(s)
  玉井郁巳
- Organizer
  第28臨床薬理阿蘇九重カンファレンス
- Place of Presentation
  ハウステンボス、(佐世保市)
- Year and Date
  2009-07-18
- Data Source
  KAKENHI-PROJECT-21390044
[Presentation] ここまでわかってきた消化管吸収における薬物吸収分子機構薬物の吸収性を調節する消化管トランスポーター2009
- Author(s)
  玉井郁巳
- Organizer
  第28臨床薬理阿蘇九重カンファレンス
- Place of Presentation
  ハウステンボス(佐世保市)
- Year and Date
  2009-07-18
- Data Source
  KAKENHI-PROJECT-21659038
[Presentation] TDMとトランスポーター研究2009
- Author(s)
  玉井郁巳
- Organizer
  日本TDM学会学術年会
- Place of Presentation
  新潟コンベンションセンター(新潟市)
- Year and Date
  2009-06-13
- Data Source
  KAKENHI-PROJECT-21659038
[Presentation] がんの診断と治療へのトランスポーター活性の利用2009
- Author(s)
  玉井郁巳
- Organizer
  日本医療薬学会年会
- Place of Presentation
  長崎医師会館(長崎市)
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-21659038
[Presentation] グルコース側鎖を有する高分子複合体の経口抗糖尿病薬としての可能性評価2009
- Author(s)
  寺岡裕美, 佐久間信至, 政岡祥江, 片岡誠, 山下伸二, 白坂善之, 玉井郁巳, 木田敏之, 明石満
- Organizer
  第31回日本バイオマテリアル学会大会
- Place of Presentation
  京都
- Year and Date
  2009-11-16
- Data Source
  KAKENHI-PROJECT-21590051
[Presentation] Polyamidoamine dendrimers enhance inhibitory effect of arbutin on SGLT1-mediated glucose uptake through their conjugation2009
- Author(s)
  Yumi Teraoka, Shinji Sakuma, Yoshie Masaoka, Makoto Kataoka, Shinji Yamashita, Yoshiyuki Shirasaka, Ikumi Tamai, Toshiyuki Kida, Mitsuru Akashi
- Organizer
  2009 American Association of Pharmaceutical Scientists(AAPS) Annual Meeting and Exposition
- Place of Presentation
  Los Angeles, CA
- Year and Date
  2009-11-11
- Data Source
  KAKENHI-PROJECT-21590051
[Presentation] 末端にグリコシル基を持つデンドリマーによるNa+/糖共輸送体阻害能の検証2009
- Author(s)
  寺岡裕美, 佐久間信至, 政岡祥江, 片岡誠, 山下伸二, 白坂善之, 玉井郁巳, 木田敏之, 明石満
- Organizer
  第25回日本DDS学会
- Place of Presentation
  東京
- Year and Date
  2009-07-03
- Data Source
  KAKENHI-PROJECT-21590051
[Presentation] トランスポーターと創薬 : メジャーをおさえてニッチで攻める2008
- Author(s)
  玉井郁巳
- Organizer
  日本薬物動態学会
- Place of Presentation
  熊本市
- Year and Date
  2008-11-01
- Data Source
  KAKENHI-PROJECT-19390046
[Presentation] ROLE OF ORGANIC ANION TRANSPORTING POLYPEPTIDE 1A4 IN HEPATIC UPTAKE OF NAFCILLIN IN RATS.2008
- Author(s)
  Yasushi Morohashi, Taiki Shimada, Yuta Shibue, Yoshiyuki Shirasaka, Yukio Kato, Ikumi Tamai
- Organizer
  日本薬物動態学会
- Place of Presentation
  熊本市
- Year and Date
  2008-10-31
- Data Source
  KAKENHI-PROJECT-19390046
[Presentation] 有機アニオントランスポーターを利用した医薬品の吸収・組織移行至適化と薬効標的への応用2008
- Author(s)
  玉井郁巳
- Organizer
  日本DDS学会
- Place of Presentation
  東京
- Year and Date
  2008-06-29
- Data Source
  KAKENHI-PROJECT-19390046
[Presentation] ROLE OF ORGANIC ANION TRANSPORTING POLYPEPTIDE 1A4 IN HEPATIC UPTAKE OF NAFCILLIN IN RATS2008
- Author(s)
  Yasushi Morohashi, Taiki Shimada, Yuta Shibue, Yoshiyuki Shirasaka, Yukio Kato, Ikumi Tamai
- Organizer
  日本薬物動態学会
- Place of Presentation
  熊本
- Year and Date
  2008-10-31
- Data Source
  KAKENHI-PROJECT-19390046
[Presentation] Drug-induced Inhibition and Activation of Physiological Transporters :2008
- Author(s)
  Ikumi Tamai
- Organizer
  Asian-Pacific ISSX Meeting
- Place of Presentation
  Shanghai, China
- Year and Date
  2008-05-10
- Data Source
  KAKENHI-PROJECT-19390046
[Presentation] Sandwich cultureを評価系として用いた肝トランスポーター活性可視化に関する研究2008
- Author(s)
  吉田憲司、中村利通、白坂善之、玉井郁巳
- Organizer
  第128回日本薬学会年会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-19390046
[Presentation] 有機アニオントランスポーターを利用した医薬品の吸収・組織移行至適化と薬効標的への応用2008
- Author(s)
  玉井郁巳
- Organizer
  日本DDS 学会
- Place of Presentation
  東京
- Year and Date
  2008-06-29
- Data Source
  KAKENHI-PROJECT-19390046
[Presentation] トランスポーターと創薬 : メジャーをおさえてニッチで攻める2008
- Author(s)
  玉井郁巳
- Organizer
  日本薬物動態学会
- Place of Presentation
  熊本
- Year and Date
  2008-11-01
- Data Source
  KAKENHI-PROJECT-19390046
[Presentation] Drug-induced Inhibition and Activation of Physiological Transporters2008
- Author(s)
  Ikumi Tamai
- Organizer
  Asian-Pacific ISSX Meeting
- Place of Presentation
  Shanghai, China
- Year and Date
  2008-05-10
- Data Source
  KAKENHI-PROJECT-19390046
[Presentation] Sandwich culture を評価系として用いた肝トランスポーター活性可視化に関する研究2008
- Author(s)
  吉田憲司、中村利通、白坂善之、玉井郁巳
- Organizer
  第128 回日本薬学会年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-19390046
[Presentation] Comparison of Hepatic Uptake of Beta-Lactam Antibiotics Mediated by OATP Transporters between Rat and Human2007
- Author(s)
  Masanori Irokawa, Taiki Shimada, Masanori Nakakariya, Yoshiyuki Shirasaka and Ikumi Tamai
- Organizer
  第29回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-19390046
[Presentation] Comparison of Hepatic Uptake of Beta-Lactam Antibiotics Mediated by OATP Transporters between Rat and Human2007
- Author(s)
  Masanori Irokawa, Taiki Shimada, Masanori Nakakariya, Yoshiyuki Shirasaka,and Ikumi Tamai
- Organizer
  第29 回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  仙台
- Year and Date
  2007-11-27
- Data Source
  KAKENHI-PROJECT-19390046
[Presentation] Substrate-Dependent Drug-Grapefruit Juice Interactions Caused by Multiple Binding Sites on OATP2B1
- Author(s)
  Takanori Mori, Yoshiyuki Shirasaka, Yukiko Murata, Takeo Nakanishi and Ikumi Tamai.
- Organizer
  第26回日本薬物動態学会年会
- Place of Presentation
  タワーホール船橋（東京都）
- Data Source
  KAKENHI-PROJECT-23590175
[Presentation] Transport Mechanism of Trans-1-amino-3-18F-fluorocyclobutanecarboxylic Acid (18F-FACBC) PET Radiotracer in Human Prostate Cancer.
- Author(s)
  Okudaira H., Oka S., Nakanishi T., Kobayashi M., Tamagami H., Schuster D.M., Goodman M.M., Shirakami Y., Tamai I., Kawai K.
- Organizer
  The Society of Nuclear Medicine 60th Annual Meeting
- Place of Presentation
  Vancouver Convention Centre (Canada)
- Data Source
  KAKENHI-PROJECT-25293260
[Presentation] A Role of Prostaglandin Transporter in Regulating PGE2 Release from Human Bronchial BEAS-2B Cells under Inflammatory Conditions
- Author(s)
  Yoshiyuki Shirasaka, Takeo Nakanishi, Taku Kasai, Megumi Scichiri, Kazuyuki Hayashi, Akio Nishiura, and Ikumi Tamai.
- Organizer
  第26回日本薬物動態学会年会
- Place of Presentation
  タワーホール船橋（東京都）
- Data Source
  KAKENHI-PROJECT-23590175
[Presentation] Uptake of an Estrogen Precursor in Estrogen Receptor-Positive Breast Cancer Cells: Focusing on Organic Anion Transporting Polypeptide 2B1
- Author(s)
  Jun Matsumoto, Noritaka Ariyoshi, Masahiro Sakakibara, Takeo Nakanishi, Yoshiyuki Okubo, Nobumitsu Shiina, Kaoru Fujisaki, Yukio Nakatani, Ikumi Tamai, Takeshi Nagashima, Harumi Yamada, Hiroshi Takeda and Itsuko Ishii
- Organizer
  World congress on Pharmacology
- Place of Presentation
  Brisbane, Australia
- Year and Date
  2015-07-20 – 2015-07-22
- Data Source
  KAKENHI-PROJECT-25893224
[Presentation] Transport Mechanism of Trans-1-amino-3-18F-fluorocyclobutanecarboxylic Acid (18F-FACBC) PET Radiotracer in Human Prostate Cancer.
- Author(s)
  Okudaira H., Oka S., Nakanishi T., Kobayashi M., Tamagami H., Schuster D.M., Goodman M.M., Shirakami Y., Tamai I., Kawai K.
- Organizer
  The Society of Nuclear Medicine 60th Annual Meeting
- Place of Presentation
  Vancouver Convention Centre (Canada)
- Data Source
  KAKENHI-PROJECT-24659558
[Presentation] Long-Lasting Effect of Fruit Juice on Intestinal Absorptive Transporter OATP2B1
- Author(s)
  Yukiko Murata, Megumi Shichiri, Takanori Mori, Yoshiyuki Shirasaka, Takeo Nakanishi and Ikumi Tamai.
- Organizer
  第26回日本薬物動態学会年会
- Place of Presentation
  タワーホール船橋（東京都）
- Data Source
  KAKENHI-PROJECT-23590175
[Presentation] Impact of OATP2B1 expression on cell proliferation in ER-positive breast cancer.
- Author(s)
  Jun Matsumoto, Noritaka Ariyoshi, Masahiro Sakakibara, Takeo Nakanishi, Ikumi Tamai, Takeshi Nagashima and Itsuko Ishii.
- Organizer
  10th International ISSX Meeting
- Place of Presentation
  Toronto, Canada
- Data Source
  KAKENHI-PROJECT-25893224
[Presentation] Application of quantitative time-laspe imaging(QTL1) for evaluation of MRP2/MRP2-based drug-drug interaction in rat and human hepatocytes.
- Author(s)
  池永美穂、、中西猛夫、福田元、松永憲和、玉井郁巳
- Organizer
  The 27th JSSX Annual Meeting
- Place of Presentation
  タワーホール船堀（東京都）
- Data Source
  KAKENHI-PROJECT-23659076

1. TSUJI Akira (10019664)

# of Collaborated Projects: 19 results

# of Collaborated Products: 0 results
2. SAI Yoshimichi (40262589)

# of Collaborated Projects: 10 results

# of Collaborated Products: 0 results
3. NAKANISHI Takeo (30541742)

# of Collaborated Projects: 8 results

# of Collaborated Products: 52 results
4. SHIRASAKA Yoshiyuki (60453833)

# of Collaborated Projects: 7 results

# of Collaborated Products: 85 results
5. KAWAI Keiichi (30204663)

# of Collaborated Projects: 7 results

# of Collaborated Products: 12 results
6. KUNISHIMA Munetaka (10214975)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
7. KOBAYASHI Masato (30444235)

# of Collaborated Projects: 5 results

# of Collaborated Products: 7 results
8. Wakayama Tomohiko (70305100)

# of Collaborated Projects: 5 results

# of Collaborated Products: 3 results
9. YANAGIE Hironobu (30212278)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
10. AIZAWA Shin (30202443)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
11. MARUYAMA Kazuo (30130040)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
12. MAEDA Tomoji (60303294)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
13. OKAZAWA Hidehiko (50360813)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
14. TERASAKI Tetsuya (60155463)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. ERIGUCHI Masazumi (10114406)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
16. KIDA Toshiyuki (20234297)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
17. NISHII Ryuichi (60463212)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
18. 間賀田泰寛 (20209399)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
19. 中島美紀 (70266162)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
20. 水谷明日香 (00828452)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
21. MORIMOTO Kaori (90401009)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
22. OGIHARA Takuo (80448886)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
23. SAKUMA Shinji (80388644)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
24. YAMASHITA Shinji (00158156)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
25. AKASHI Mitsuru (20145460)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
26. FUJIBAYASHI Yasuhisa (50165411)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. KOMORI Hisakazu (00634180)

# of Collaborated Projects: 1 results

# of Collaborated Products: 15 results
28. JUN Matsumoto (60709012)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
29. ISHII Itsuko (00202929)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
30. ARIYOSHI Noritaka (00243957)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
31. NAGASHIMA Takeshi (60292710)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
32. SAKAKIBARA Masahiro (70375632)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
33. HAYAKAWA Jun-ichiro (50110622)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. KUWAJIMA Masamichi (00205262)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. HASHIMOTO Noriyoshi (50242524)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. HAGA Makoto (70110666)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. KIZU Ryoichi (80143915)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. TANI Kenzaburo (00183864)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. KONO Kenji (90215187)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. KOYAMA Yoshiyuki (00162090)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. Goto Kyoko (50180245)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
42. SHIKANO Naoto (80295435)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
43. NISHI Kodai (10719496)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
44. 石田康 (20212897)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
45. 久下裕司 (70321958)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
46. 吉崎巖 (70200970)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
47. 荒川大 (40709028)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
48. 鷲山幸信 (80313675)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
49. 絹谷清剛 (20281024)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
50. 若林大志 (60622818)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
51. 菅原太一 (30758412)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
52. Takeuchi Ryota

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
53. KIDANI Yoshinori

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
54. GOTO Masuo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
55. INNIS B Robert

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
56. 喜谷喜徳

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
57. KAWAGUCHI Atsushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
58. 水谷陽一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
59. 中嶋美紀

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
60. 東村泰希

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
61. 工藤崇

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
62. 今野翔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

tamai ikumi 玉井 郁巳

TAMAI Ikumi 玉井 郁巳

玉井 郁己 タマイ イクミ

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血清尿酸値を感受する尿酸センサーの同定と生理作用Principal Investigator

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Regulation of intestinal function via microRNA from fruit-derived microvesiclesPrincipal Investigator

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Drug-food interaction on transportersPrincipal Investigator

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Micro RNA-mediated expressional regulation of transportersPrincipal Investigator

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Local drug-drug interaction of donepezil with cilostazol at BCRP transporterPrincipal Investigator

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tamai ikumi 玉井郁巳

TAMAI Ikumi 玉井郁巳

玉井郁己タマイイクミ