Goto Kyoko 後藤享子

… Alternative Names

Researcher Number	50180245
Other IDs	https://orcid.org/0000-0002-1642-6538
Affiliation (Current)	2022: 金沢大学, 薬学系, 准教授
Affiliation (based on the past Project Information) *help	2013 – 2021: 金沢大学, 薬学系, 准教授 1996: 金沢大学, 薬学部, 助手 1992 – 1994: 金沢大学, 薬学部, 助手 1990: 金沢大学, 薬学部 1990: 金沢大学, 薬学部, 助手 1988: 金沢大学, 薬学部, 教務職員
Review Section/Research Field	Principal Investigator Chemical pharmacy / Natural medicines / Drug development chemistry / Basic Section 47050:Environmental and natural pharmaceutical resources-related Except Principal Investigator Chemical pharmacy / Risk sciences of radiation and chemicals / Urology / Basic Section 56030:Urology-related / Basic Section 63020:Radiation influence-related
Keywords	Principal Investigator 生理活性天然物 / 熱帯雨林産植物 / 熱帯林産植物 / indolo[2,3-a]carbazole / 抗ガン作用 / Diels-Alder反応 / l-hydroxyindole / 抗がん剤リード / 熱帯林植物 / 抗がん剤候補 … More Except Principal Investigator ケミカルバイオロジー / ヌクレオチド除去修復 / 阻害剤 / 麦角アルカロイド / 1-ヒドロキシインドール / インドール / ファイトアレキシン / 低分子化合物 / 前立腺癌 / KSU1415 / ChanoclavineーI acid / 4位置換インド-ル / 2位置換インド-ル / 1ーヒドロキシインド-ル / セロトニン / メラトニン / 求核置換反応 / トリプトファン / アブラナ科植物 / 血小板凝集阻止 / アブラナ科の野菜 / インジゴ / インドロカルバゾール / 化合物ライブラリー / スクリーニング / タリウム化合物 / 4位置換インドール / 7位置換インドール / サイタル反応 / ニトロインドール / アジドインドール / 有機ケイ素化合物 / シスプラチン / オラパリブ / 癌治療 / 癌 / 遺伝学 / 遺伝子 / 薬学 / 微小環境 / 癌細胞間作用 / フラボノイド誘導体 / 抗癌剤耐性 / フラボノイド / 薬剤耐性 / 去勢抵抗性前立腺癌 / タキサン耐性 / クロストーク / taxane系耐性前立腺癌 / Taxane系耐性前立腺癌 / 去勢抵抗性 / タキサン抵抗性 / コーヒー / ジテルペン / DNA損傷プローブ Less

ジデルペンによる前立腺癌進展制御機構の解明と新規化合物の開発
- Principal Investigator
  
  泉浩二
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Kanazawa University
ヌクレオチド除去修復機構解明に向けたケミカルアプローチ
- Principal Investigator
  
  松永司
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 63020:Radiation influence-related
- Research Institution
  Kanazawa University
希少熱帯資源から新規創薬リードへの展開Principal Investigator
- Principal Investigator
  
  後藤享子
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Kanazawa University
The development of the innovative therapeutic drugs which targete crosstalk in the prostate cancer microenvironment
- Principal Investigator
  
  MIZOKAMI Atsushi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Kanazawa University
Mechanistic analysis of novel DNA repair inhibitors and their possible application to anticancer therapy
- Principal Investigator
  
  Matsunaga Tsukasa
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Kanazawa University
Phytochemistry study of Indonesian authigenic and traditional medicinal plantsPrincipal Investigator
- Principal Investigator
  
  Nakagawa-Goto Kyoko
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Natural medicines
- Research Institution
  Kanazawa University
Application of chemical biology to a mechanistic study of human nucleotide excision repair
- Principal Investigator
  
  MATSUNAGA Tsukasa
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Kanazawa University
Discovery of antitumor drug candidates from rainforest plantsPrincipal Investigator
- Principal Investigator
  
  Goto Kyoko
- Project Period (FY)
  2013 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Natural medicines
- Research Institution
  Kanazawa University
Chemical biology of MDR cancer selective cytotoxicity using natural product derivativesPrincipal Investigator
- Principal Investigator
  
  Goto Kyoko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Drug development chemistry
- Research Institution
  Kanazawa University
1-ヒドロキシインドール化学の展開と、循環器系疾患治療薬の開拓研究
- Principal Investigator
  
  染井正徳
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kanazawa University
新規抗ガン性indolo[2,3-a]carbazole化合物群の合成研究Principal Investigator
- Principal Investigator
  
  中川享子
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kanazawa University
薬理活性1-ヒドロキシインドール化合物群の合成と反応
- Principal Investigator
  
  染井正徳
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kanazawa University
薬理活性4位窒素置換benz[cd]indole化合物群の合成研究Principal Investigator
- Principal Investigator
  
  中川享子
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kanazawa University
薬理活性インド-ル化合物群の合成研究
- Principal Investigator
  
  染井正徳
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kanazawa University
2位に置換基を持つ新規な三環性麦角アルカロイド誘導体の合成研究Principal Investigator
- Principal Investigator
  
  中川享子
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kanazawa University
有機金属化合物を利用した環状化合物の新規クロスカップリング反応開拓研
- Principal Investigator
  
  染井正徳
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kanazawa University

All 2021 2020 2019 2018 2017 2016 2015 2013 Other

All Journal Article Presentation Patent

[Journal Article] Anti-proliferative and anti-migratory properties of coffee diterpenes kahweol acetate and cafestol in human renal cancer cells.2021
- Author(s)
  Makino T, Izumi K, Hiratsuka K, Kano H, Shimada T, Nakano T, Kadomoto S, Naito R, Iwamoto H, Yaegashi H, Shigehara K, Kadono Y, Nakata H, Saito Y, Nakagawa-Goto K, Sakai N, Iwata Y, Wada T, Mizokami A.
- Journal Title
  
  Scientific reports
  
  Volume: 11 Pages: 675-675
- DOI
  10.1038/s41598-020-80302-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08426, KAKENHI-PROJECT-19K09685, KAKENHI-PROJECT-20K09574
[Journal Article] Bicyclic Chalcones as Mitotic Inhibitors for Overcoming Androgen Receptor-Independent and Multidrug Resistant Prostate Cancer2021
- Author(s)
  Saito Y, Mizokami M, Maeda S, Takahashi K, Izumi K, Goto M, Nakagawa-Goto K
- Journal Title
  
  ACS Omega
  
  Volume: 6 Pages: 4842-4849
- DOI
  10.1021/acsomega.0c05822
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02583
[Journal Article] First Total Synthesis of a Pavine Alkaloid, (±)-Neocaryachine, and its Optical Resolution2020
- Author(s)
  Miura Y, Saito Y, Goto M, Nakagawa-Goto K.
- Journal Title
  
  Chem. Pharm. Bull
  
  Volume: 68 Pages: 899-902
- DOI
  10.1248/cpb.c20-00370
- NAID
  130007893858
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02583
[Journal Article] Palasanines A-E, 3,4-Methylenedioxyquinoline Alkaloids Fused with a Phenyl-14-oxabicyclo[3.2.1]octane Unit from Melochia umbellata var. deglabrata2020
- Author(s)
  Rahim A, Saito Y, Fukuyoshi S, Miyake K, Goto M, Chen CH, Alam G, Lee KH, Nakagawa-Goto K.
- Journal Title
  
  J. Nat. Prod.
  
  Volume: 83 Pages: 2931-2939
- DOI
  10.1021/acs.jnatprod.0c00454
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02583
[Journal Article] Development of an efficient scale-up synthesis for β3-adrenergic receptor agonist, ritobegron ethyl hydrochloride2020
- Author(s)
  Sonehara J, Tamai T, Isawa H, Hotei Y, Kasai K, Kikuchi N, Ishikawa T, Kobayashi M, Ozawa T, Suzuki R, Kobayashi M, Ainai T, Nishimura M, Saito Y, Nakagawa-Goto K
- Journal Title
  
  Org. Proc. Res. Dev
  
  Volume: 24 Pages: 1675-1682
- DOI
  10.1021/acs.oprd.0c00278
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02583
[Journal Article] Novel Furoquinolinones from an Indonesian Plant, Lunasia amara2020
- Author(s)
  M. Yamashita, Y. Saito, A. Rahim, S. iFukuyoshi, K. Miyake, M. Goto, K. Nakagawa-Goto
- Journal Title
  
  Tetrahedron Lett
  
  Volume: in press Pages: 151861-151861
- DOI
  10.1016/j.tetlet.2020.151861
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05811, KAKENHI-PROJECT-18H02583
[Journal Article] Spiro[3.5]nonenyl meroterpenoid lactones, cryptolaevilactones G-L, an ionone derivative and total synthesis of cryptolaevilactone M from Cryptocarya laevigata2019
- Author(s)
  Tsurumi F, Miura Y, Nakano M, Saito Y, Fukuyoshi S, Newman DJ, O’Keefe BR, Lee KH, Nakagawa-Goto K
- Journal Title
  
  J Nat Prod
  
  Volume: 82 Pages: 2368-2378
- DOI
  10.1021/acs.jnatprod.8b00732
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02583
[Journal Article] Prenylated acetophloroglucinol dimers from Acronychia trifoliolata: Structure elucidation and total synthesis2019
- Author(s)
  Miyake K, Morita C, Suzuki A, Matsushita N, Saito Y, Goto M, Newman DJ, O’Keefe BR, Lee KH, Nakagawa-Goto K
- Journal Title
  
  J Nat Prod
  
  Volume: 82 Pages: 2852-2858
- DOI
  10.1021/acs.jnatprod.9b00596
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02583
[Journal Article] Isolation, Structure Elucidation, and Antiproliferative Activity of Butanolides and Lignan Glycosides from the Fruit of Hernandia nymphaeifolia2019
- Author(s)
  Aimaiti S, Saito Y, Fukuyoshi S, Goto M, Miyake K, Newman DJ, O’Keefe BR, Lee KH, Nakagawa-Goto K
- Journal Title
  
  Molecules
  
  Volume: 24 Pages: 4005-4021
- DOI
  10.3390/molecules24214005
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02583
[Journal Article] Synthesis of 4-epi-parviflorons A, C and E: Structure-activity relationship study of antiproliferative abietane derivatives2019
- Author(s)
  Miyajima, Y.; Saito, Y.; Takeya, M.; Goto, M.; Nakagawa-Goto, K.
- Journal Title
  
  J Org Chem
  
  Volume: 84 Pages: 3239-3248
- DOI
  10.1021/acs.joc.8b02832
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14344, KAKENHI-PROJECT-18H02583
[Journal Article] Anti-proliferative and chemosensitizing effects of diarylheptanoids on human tumor cell lines2019
- Author(s)
  Miyagishi S, Saito Y, Goto M, Nakagawa-Goto K
- Journal Title
  
  ACS Omega
  
  Volume: 4 Pages: 2053-2062
- DOI
  10.1021/acsomega.8b03215
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02583
[Journal Article] Kleinhospitine E and cycloartane triterpenoids from Kleinhovia hospita L2018
- Author(s)
  Rahim A, Saito Y, Miyake K, Goto M, Chen CH, Alam G, Morris-Natchke S, Lee KH, Nakagawa-Goto K
- Journal Title
  
  J Nat Prod
  
  Volume: 81 Pages: 1619-1627
- DOI
  10.1021/acs.jnatprod.8b00211
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05811
[Journal Article] Corymbulosins I-W, Cytotoxic Clerodane Diterpenes from the Bark of Laetia corymbulosa2018
- Author(s)
  Aimaiti Simayijiang、Suzuki Airi、Saito Yohei、Fukuyoshi Shuichi、Goto Masuo、Miyake Katsunori、Newman David J.、O’Keefe Barry R.、Lee Kuo-Hsiung、Nakagawa-Goto Kyoko
- Journal Title
  
  The Journal of Organic Chemistry
  
  Volume: 83 Pages: 951-963
- DOI
  10.1021/acs.joc.7b02951
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293024
[Journal Article] 5’-Chloro-2,2’-dihydroxychalcone and Related Flavanoids as Treatments for Prostate Cancer2018
- Author(s)
  Saito Y, Mizokami A, Tsurimoto H, Izumi K, Goto M, Nakagawa-Goto K
- Journal Title
  
  Eur J Med Chem
  
  Volume: 157 Pages: 1143-1152
- DOI
  10.1016/j.ejmech.2018.08.069
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02583
[Journal Article] Total Synthesis of Antiproliferative Parvifloron F2018
- Author(s)
  Saito Yohei、Goto Masuo、Nakagawa-Goto Kyoko
- Journal Title
  
  Organic Letters
  
  Volume: 20 Pages: 628-631
- DOI
  10.1021/acs.orglett.7b03763
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293024
[Journal Article] Secondary Metabolites, Monoterpene?Polyketides Containing a Spiro[3.5]nonane from Cryptocarya laevigata2018
- Author(s)
  Tsurumi Fumika、Miura Yuta、Saito Yohei、Miyake Katsunori、Fujie Tetsuo、Newman David J.、O’Keefe Barry R.、Lee Kuo-Hsiung、Nakagawa-Goto Kyoko
- Journal Title
  
  Organic Letters
  
  Volume: 20 Pages: 2282-2286
- DOI
  10.1021/acs.orglett.8b00624
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293024
[Journal Article] Antiproliferative alkaloids from Alangium longiflorum, an endangered tropical plant species2018
- Author(s)
  Takeuchi M, Saito Y, Goto M, Miyake K, Newman DJ, O’Keefe BR, Lee KH, Nakagawa-Goto K.
- Journal Title
  
  J Nat Prod
  
  Volume: 81 Pages: 1884-1891
- DOI
  10.1021/acs.jnatprod.8b00411
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02583
[Journal Article] Phytoagent Deoxyelephantopin and Its Derivative Inhibit Triple Negative Breast Cancer Cell Activity through ROS-Mediated Exosomal Activity and Protein Functions2017
- Author(s)
  Shiau Jeng-Yuan、Chang Yong-Qun、Nakagawa-Goto Kyoko、Lee Kuo-Hsiung、Shyur Lie-Fen
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 8 Pages: 1-15
- DOI
  10.3389/fphar.2017.00398
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293024
[Journal Article] Phenylethylchromones with in vitro antitumor promoting activity from Aquilaria filarial2017
- Author(s)
  Suzuki A, Miyake K, Saito Y, Faradiba, Tokuda H, Takeuchi M, Suzuki N, Ichiishi E, Fujie T, Goto M, Sasaki S, Nakagawa-Goto K
- Journal Title
  
  Planta Medica
  
  Volume: 83 Pages: 300-305
- DOI
  10.1055/s-0042-110858
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293024
[Journal Article] Corymbulosins D-H, 2-hydroxy- and 2-oxo-clerodane diterpenes from the bark of Laetia corymbulosa2017
- Author(s)
  Suzuki A, Fukuyoshi S, Saito Y, Goto M, Miyake K, Newman DJ, O’Keefe BR, Lee KH, Nakagawa-Goto K
- Journal Title
  
  Journal of Natural Products
  
  Volume: ASAP
- DOI
  10.1021/acs.jnatprod.6b01151
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293024
[Journal Article] Phytoagent deoxyelephantopin derivative inhibits triple negative breast cancer cell activity by inducing oxidative stress-mediated paraptosis-like cell death2017
- Author(s)
  Shiau Jeng-Yuan、Nakagawa-Goto Kyoko、Lee Kuo-Hsiung、Shyur Lie-Fen
- Journal Title
  
  Oncotarget
  
  Volume: 8 Pages: 56942-56958
- DOI
  10.18632/oncotarget.18183
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293024
[Journal Article] (－)-Neocaryachine, An antiproliferative pavine alkaloid from Cryptocarya laevigata Induces DNA Double-strand Breaks2017
- Author(s)
  Suzuki Y, Saito Y, Goto M, Newman DJ, O’Keefe BR, Lee KH, Nakagawa-Goto K
- Journal Title
  
  Journal of Natural Products
  
  Volume: 80 Pages: 220-224
- DOI
  10.1021/acs.jnatprod.6b01153
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293024
[Journal Article] A Novel Clerodane Diterpene from <i>Vitex cofassus</i>2017
- Author(s)
  Rasyid FA, Fukuyoshi S, Ando H, Miyake K, Atsumi T, Fujie T, Saito Y, Goto M, Shinya T, Mikage M, Sasaki, Nakagawa-Gotoa K
- Journal Title
  
  CHEMICAL & PHARMACEUTICAL BULLETIN
  
  Volume: 65 Issue: 1 Pages: 116-120
- DOI
  10.1248/cpb.c16-00775
- NAID
  130005187753
- ISSN
  0009-2363, 1347-5223
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293024
[Journal Article] Antitubulin effects of aminobenzothiophene-substituted triethylated chromones2017
- Author(s)
  Kobayashi Yukiko、Saito Yohei、Goto Masuo、Nakagawa-Goto Kyoko
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 27 Pages: 2731-2735
- DOI
  10.1016/j.bmcl.2017.04.055
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293024
[Journal Article] Novel sesquiterpene lactone analogues as potent anti-breast cancer agents2016
- Author(s)
  Nakagawa-Goto K, Chen JY,　Cheng YT, Lee WL, Takeya, M, Saito Y, Lee KH, Shyur LF
- Journal Title
  
  Molecular Oncology
  
  Volume: -
- DOI
  10.1016/j.molonc.2016.03.002
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293024
[Journal Article] Total synthesis and in vitro anti tumor-promoting activity of racemic acetophenone monomers from Acronychia trifoliolata2016
- Author(s)
  Morita C, Kobayashi Y, Tokuda H, Saito Y, Miyake M, Suzuki N, Ichiishi E, Lee KH, Nakagawa-Goto K
- Journal Title
  
  Journal of Natural Products
  
  Volume: 79 Pages: 2890-2897
- DOI
  10.1021/acs.jnatprod.6b00646
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293024
[Journal Article] Triethylated chromones with substituted naphthalenes as novel tubulin inhibitors2016
- Author(s)
  Nakagawa-Goto K, Taniguchi Y, Watanabe Y, Oda A, Ohkoshi E, Hamel E, Lee KH, Goto M
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 24 Pages: 6048-6057
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293024
[Journal Article] Acetophenone monomers from Acronychia trifoliolata2016
- Author(s)
  Miyake M, Suzuki A, Morita C, Goto M, Newman DJ, O’Keefe B, Morris-Natschke SL, Lee KH, Nakagawa-Goto K
- Journal Title
  
  Journal of Natural Products
  
  Volume: 79 Pages: 2883-2889
- DOI
  10.1021/acs.jnatprod.6b00645
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293024
[Journal Article] A novel plant sesquiterpene lactone derivative DETD-35 suppresses BRAFV600E mutant melanoma growth and overcomes acquired vemurafenib resistance in mice2016
- Author(s)
  Feng JH, Nakagawa-Goto K, Lee KH, Shyur LF
- Journal Title
  
  Molecular Cancer Therapeutics
  
  Volume: -
- DOI
  10.1158/1535-7163.mct-15-0973
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293024
[Journal Article] Development of a novel class of tubulin inhibitor from desmosdumotin B with a hydroxylated bicyclic B-ring2015
- Author(s)
  Nakagawa-Goto K, Oda A, Hamel E, Ohkoshi E, Bastow KF, Lee KH, Goto M
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 58 Pages: 2378-2389
- DOI
  10.1021/jm501859j
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293024, KAKENHI-PROJECT-26460034, KAKENHI-PUBLICLY-15H01064, KAKENHI-PROJECT-25670054
[Patent] トリプルネガティブ乳がん選択的抗腫瘍活性を有するパルビフロロン誘導体2018
- Inventor(s)
  後藤享子、斎藤洋平、宮島由衣
- Industrial Property Rights Holder
  後藤享子、斎藤洋平、宮島由衣
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-25293024
[Patent] エピミノジベンゾアヌレン骨格を有する新規抗がん剤候補2016
- Inventor(s)
  後藤享子、鈴木結貴、齋藤洋平
- Industrial Property Rights Holder
  後藤享子、鈴木結貴、齋藤洋平
- Industrial Property Rights Type
  特許
- Filing Date
  2016-04-01
- Data Source
  KAKENHI-PROJECT-25293024
[Patent] Preparation of novel sesquiterpene derivatives and their use in inflammation and cancer treatment2015
- Inventor(s)
  Lee KH, Nakagawa-Goto K, et al
- Industrial Property Rights Holder
  Lee KH, Nakagawa-Goto K, et al
- Industrial Property Rights Type
  特許
- Filing Date
  2015-12-10
- Overseas
- Data Source
  KAKENHI-PROJECT-25293024
[Patent] Novel sesquiterpene derivatives and their use in inflammation or cancer treatment2015
- Inventor(s)
  Shyur LF, Nakagawa-Goto K, et al
- Industrial Property Rights Holder
  Shyur LF, Nakagawa-Goto K, et al
- Industrial Property Rights Type
  特許
- Filing Date
  2015-05-06
- Overseas
- Data Source
  KAKENHI-PROJECT-25293024
[Presentation] ブロモエレモフィランPC-Aの全合成と抗トリプルネガティブ乳がん選択性における構造活性相関研究2021
- Author(s)
  前田紗弥加，佐賀野　桃子，斎藤　洋平，後藤（中川）享子
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-18H02583
[Presentation] 再燃前立腺がんに有効なα置換フェニルスチリルケトン誘導体の創出と作用機序に関する研究2021
- Author(s)
  斎藤洋平，溝上敦，泉浩二，内藤伶奈人，後藤益生，後藤（中川）享子
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-18H02583
[Presentation] モノテルペン－ポリケチドCryptolaevilactone類の合成研究2021
- Author(s)
  三浦悠太，斎藤洋平，後藤（中川）享子
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-18H02583
[Presentation] 生体分子の化学修飾を志向した温和な条件におけるボロキサゾリドン形成2021
- Author(s)
  斎藤洋平，吉田菜々美，後藤（中川）享子
- Organizer
  日本化学会第101春季年会
- Data Source
  KAKENHI-PROJECT-18H02583
[Presentation] スピロ[3.5]ノナン骨格含有メロテルペノイドCryptolaevilactone類の全合成研究2020
- Author(s)
  三浦悠太，斎藤洋平，後藤（中川）享子
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-18H02583
[Presentation] 薬用生理活性天然物の単離精製・合成・メディシナルケミストリーへの展開2020
- Author(s)
  後藤（中川）享子
- Organizer
  日本薬学会第140年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02583
[Presentation] トリプルネガティブ乳がん選択的な細胞増殖抑制効果をもつエレモフィラン型セスキテルペンPC-Aの合成2020
- Author(s)
  前田紗弥加，佐賀野　桃子，斎藤　洋平，後藤（中川）享子
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-18H02583
[Presentation] 勢抵抗性前立腺がんに有効なカルコン誘導体の創出と標的タンパク質の探索2020
- Author(s)
  斎藤洋平，溝上敦，泉浩二，内藤伶奈人，後藤益生，後藤（中川）享子
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-18H02583
[Presentation] Acronychia trifoliolata 由来の新規アセトフェノンダイマー類の合成とがん細胞増殖抑制効果2019
- Author(s)
  松下夏子，森田千尋，斎藤洋平，後藤益生，後藤（中川）享子
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-18H02583
[Presentation] Thio-salvinal 誘導体群の合成，がん細胞増殖抑制効果と構造活性相関研究2019
- Author(s)
  吉田奈々美，小林由希子，斎藤洋平，後藤益生，後藤（中川）享子
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-18H02583
[Presentation] Cryptocarya laevigata由来モノテルペン-ポリケチドcryptolaevilactones A-Fの合成2019
- Author(s)
  三浦悠太，斎藤洋平，後藤（中川）享子
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-18H02583
[Presentation] トリプルネガティブ乳がん選択的に増殖抑制活性を示す天然物誘導体プローブの設計と合成2019
- Author(s)
  坂田耕一，斎藤洋平，後藤（中川）享子
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-18H02583
[Presentation] Cryptocarya laevigata由来モノテルペン-ポリケチドcryptolaevilactones A–Fの合成2019
- Author(s)
  三浦悠太，斎藤洋平，後藤（中川）享子
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-18H02583
[Presentation] 去勢抵抗性前立腺がん克服を目指したカルコン誘導体の創出2018
- Author(s)
  齋藤洋平、溝上敦、泉浩二、内藤伶奈人、後藤益生、後藤（中川）享子
- Organizer
  日本化学会第98春季年会
- Data Source
  KAKENHI-PROJECT-25293024
[Presentation] 熱帯雨林植物ハスノハギリ科Hernandia peltataの成分研究2018
- Author(s)
  Simayijiang Aimaiti、斎藤洋平、後藤益生、David J. Newman、Barry R. O’Keefe、 Kuo-Hsiung Lee、後藤（中川）享子
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-25293024
[Presentation] 新規ラクトン化合物Cryptolaevilactone M の合成と絶対立体構造の決定2018
- Author(s)
  中野美咲、齋藤洋平、後藤（中川）享子
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-25293024
[Presentation] 各種ベンゾチオフェンフラボノイド誘導体の合成とがん細胞増殖抑制効果2018
- Author(s)
  平澤幸香，谷口由花子，佐賀野桃子，斎藤洋平，後藤益生，後藤（中川）享子
- Organizer
  第36回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-18H02583
[Presentation] Quinoline Alkaloids from Melochia umbellata (Houtt.) Stapf. var. degrabrata2018
- Author(s)
  Abdul Rahim, Yohei Saito, Gemini Alam, Masuo Goto, Kyoko Nakagawa-Goto
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16H05811
[Presentation] 新規ラクトン化合物Cryptolaevilactones AーCの合成と絶対立体構造の決定2018
- Author(s)
  三浦悠太、齋藤洋平、後藤（中川）享子
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-25293024
[Presentation] ベンゾチオフェンフラボノイド誘導体のがん細胞増殖抑制効果と構造活性相関2018
- Author(s)
  平澤幸香、谷口由花子、齋藤洋平、後藤益生、後藤（中川）享子
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-25293024
[Presentation] ジアリールヘプタノイド誘導体のがん化学療法増感効果2018
- Author(s)
  宮岸佐衣，斎藤洋平，後藤益生，後藤（中川）享子
- Organizer
  第36回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-18H02583
[Presentation] 生理活性フラボノイドTEDB-TBのアミノ誘導体合成と活性評価2018
- Author(s)
  斎藤洋平，小林佑希子，後藤益生，後藤（中川）享子
- Organizer
  日本ケミカルバイオロジー学会第 13回年会
- Data Source
  KAKENHI-PROJECT-18H02583
[Presentation] エレモフィラン型セスキテルペンPC-Aの合成とトリプルネガティブ乳がん細胞選択的増殖抑制評価2018
- Author(s)
  佐賀野桃子，斎藤洋平，後藤益生，後藤（中川）享子
- Organizer
  第36回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-18H02583
[Presentation] Noreremophilane誘導体の合成とトリプルネガティブ乳がん細胞選択的増殖抑制効果2018
- Author(s)
  佐賀野桃子、齋藤洋平、後藤益生、後藤（中川）享子
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-25293024
[Presentation] 生理活性ジテルペン、パルビフロロンFの全合成2017
- Author(s)
  齋藤洋平、後藤益生、後藤（中川）享子
- Organizer
  日本化学会第97春季年会
- Place of Presentation
  東京
- Year and Date
  2017-03-22
- Data Source
  KAKENHI-PROJECT-25293024
[Presentation] 去勢抵抗性前立腺がんに有効なフラボノイド誘導体の創出研究2017
- Author(s)
  斎藤洋平、溝上敦、泉浩二、武澤雄太、後藤益生、後藤（中川）享子
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-27
- Data Source
  KAKENHI-PROJECT-25293024
[Presentation] 4-epi-Parvifloron類の合成と抗トリプルネガティブ乳がん選択性向上にむけての試み2017
- Author(s)
  宮島由衣、竹谷宗久、斎藤洋平、後藤益生、後藤（中川）享子
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-26
- Data Source
  KAKENHI-PROJECT-25293024
[Presentation] 天然物基本骨格から細胞周期阻害剤の創成2017
- Author(s)
  後藤（中川）享子
- Organizer
  第129回薬学会北陸支部例会
- Invited
- Data Source
  KAKENHI-PROJECT-25293024
[Presentation] Total Synthesis of Bioactive Diterpene, Parvifloron F2017
- Author(s)
  Saito Y, Goto M, Nakagawa-Goto K
- Organizer
  254th ACS National Meeting & Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293024
[Presentation] 4-epi-Parvifloron類の合成と抗トリプルネガティブ乳がん選択性向上にむけての試み2017
- Author(s)
  宮島由衣、竹谷宗久、斎藤洋平、後藤益生、後藤（中川）享子
- Organizer
  第15回次世代を担う若手のためのフィジカル・フォーラム
- Data Source
  KAKENHI-PROJECT-25293024
[Presentation] 熱帯雨林植物の成分研究：Acronychia trifoliolata に含有されるアセトフェノンダイマー2017
- Author(s)
  三宅克典、鈴木愛理、後藤益生、David J. Newman、Gordon M. Cragg、Barry O’Keefe、Kuo-Hsiung Lee、後藤（中川）享子
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-26
- Data Source
  KAKENHI-PROJECT-25293024
[Presentation] ヤナギ科Laetia corymbulosaから単離された新規クレロダンジテルペン, corymbulosins D-Lと抗腫瘍活性2017
- Author(s)
  鈴木愛理，SIMAYIJIANG AIMAITI、福吉修一、斎藤洋平、後藤益生、David J. Newman、Barry R. O’Keefe、 Kuo-Hsiung Lee、後藤（中川）享子
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-26
- Data Source
  KAKENHI-PROJECT-25293024
[Presentation] Kleinhospitine E and New Cycloartane Triterpenoids from Kleinhovia hospita Linn.2017
- Author(s)
  Abdul Rahim，Yohei Saito, Masuo Goto, Kyoko Nakagawa-Goto
- Organizer
  日本生薬学会第64回年会
- Data Source
  KAKENHI-PROJECT-16H05811
[Presentation] 抗腫瘍活性を有するパビンアルカロイドの合成、構造活性相関研究ならびに作用機序の解明2017
- Author(s)
  三浦悠太、鈴木結貴、斎藤洋平、後藤益生、後藤（中川）享子
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-27
- Data Source
  KAKENHI-PROJECT-25293024
[Presentation] Parvifloron類を含むアビエタン誘導体の抗腫瘍活性評価と構造活性相関2016
- Author(s)
  宮島由衣、斎藤洋平、竹谷宗久、後藤益生、後藤（中川）享子
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-25293024
[Presentation] TEDB-TB窒素置換誘導体の合成と抗腫瘍活性評価2016
- Author(s)
  小林佑希子、斎藤洋平、後藤益生、後藤（中川）享子
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-25670054
[Presentation] インドネシア産Agarwoodから単離された2-(2-Phenylethyl)chromone類と発がん抑制効果2016
- Author(s)
  鈴木愛理，FARADIBA　AbdulRasyid、三宅克典、斎藤洋平、徳田春邦、鈴木信孝、後藤益生、佐々木陽平、後藤（中川）享子
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-25293024
[Presentation] Acronychia trifoliolata含有のアセトフェノンモノマー体の合成2016
- Author(s)
  森田千尋、小林佑希子、斎藤洋平、三宅克典、後藤（中川）享子
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-25293024
[Presentation] 熱帯雨林植物の成分研究　Acronychia trifoliolataに含有されるアセトフェノンモノマー2016
- Author(s)
  三宅克典、鈴木愛理、後藤益生、David J.Newman、Gordon M. Cragg、Barry O’Keefe、Kuo-Hsiung Lee、後藤（中川）享子
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-25293024
[Presentation] ベンゾチオフェンフラボノイド誘導体の抗腫瘍活性と構造活性相関2016
- Author(s)
  谷口由花子、釣本浩行、斎藤洋平、後藤益生、後藤（中川）享子
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-25670054
[Presentation] ズキ科Alangium longiforumから単離されたアルカロイド成分2016
- Author(s)
  竹内美沙、斎藤洋平、後藤益生、David J. Newman、Gordon M. Cragg、Barry O’Keefe、Kuo-Hsiung Lee、後藤（中川）享子
- Organizer
  日本生薬学会第63回年会
- Place of Presentation
  富山
- Year and Date
  2016-09-24
- Data Source
  KAKENHI-PROJECT-25293024
[Presentation] Benzothiophenyl flavones as new classes of mitotic inhibitors2015
- Author(s)
  Taniguchi Y, Tsurimoto H, Saito Y, Hamel E, Goto M, Nakagawa-Goto K
- Organizer
  250th ACS National Meeting & Exposition
- Place of Presentation
  アメリカ、ボストン
- Year and Date
  2015-08-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25670054
[Presentation] A novel plant sesquiterpene lactone derivative DETD-35 suppresses BRAFV600E mutant melanoma growth and overcomes acquired vemurafenib resistance in mice2015
- Author(s)
  Jia-Hua Feng, Kyoko Nakagawa-Goto, Kuo-Hsiung Lee, Lie-Fen Shyur
- Organizer
  AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics
- Place of Presentation
  アメリカ　ボストン
- Year and Date
  2015-11-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293024
[Presentation] TEDB-TB Analogs as New Classes of Tubulin Inhibitors2013
- Author(s)
  後藤享子
- Organizer
  第246回アメリカ化学会ナショナルミーティング
- Place of Presentation
  インディアナポリス、アメリカ
- Data Source
  KAKENHI-PROJECT-25670054
[Presentation] Parviflorone 類の全合成と triple negative 乳がんを標的とした抗腫瘍活性評価
- Author(s)
  竹谷宗久、斎藤洋平、後藤益生、後藤（中川）享子
- Organizer
  日本薬学会第１３５年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25293024
[Presentation] 新規抗腫瘍活性ベンゾチオフェンフラボノイドの合成と構造活性相関研究
- Author(s)
  谷口由花子、釣本浩行、齋藤洋平、後藤益生、後藤（中川）享子
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-26 – 2015-03-28
- Invited
- Data Source
  KAKENHI-PROJECT-25670054

1. 染井正徳 (20110546)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. MATSUNAGA Tsukasa (60192340)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. INOBE Manabu (10312414)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. WAKASUGI Mitsuo (80345595)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. 三宅克典 (20597687)

# of Collaborated Projects: 3 results

# of Collaborated Products: 17 results
6. MIZOKAMI Atsushi (50248580)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
7. 斎藤洋平 (90723825)

# of Collaborated Projects: 2 results

# of Collaborated Products: 31 results
8. 泉浩二 (80646787)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
9. GOTO Masuo

# of Collaborated Projects: 2 results

# of Collaborated Products: 44 results
10. KUNISHIMA Munetaka (10214975)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. ODA Akifumi (50433511)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. TAMAI Ikumi (20155237)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 山田文夫 (80135087)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 向智里 (70143914)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 松浦顕教 (50836096)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. IWATA Yasunori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 角野佳史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Goto Kyoko 後藤 享子

中川 亨子 ナカガワ キョウコ

中川 享子 ナカガワ キョウコ

Research Projects

Research Products

Co-Researchers

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

希少熱帯資源から新規創薬リードへの展開Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Phytochemistry study of Indonesian authigenic and traditional medicinal plantsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Discovery of antitumor drug candidates from rainforest plantsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Chemical biology of MDR cancer selective cytotoxicity using natural product derivativesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

新規抗ガン性indolo[2,3-a]carbazole化合物群の合成研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

薬理活性4位窒素置換benz[cd]indole化合物群の合成研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Goto Kyoko 後藤享子

中川亨子ナカガワキョウコ

中川享子ナカガワキョウコ