Nagashima Takeshi 長嶋健

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NAGASHIMA Takeshi 長嶋健

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Researcher Number	60292710
Other IDs
Affiliation (Current)	2023: 千葉大学, 医学部附属病院, 准教授
Affiliation (based on the past Project Information) *help	2013 – 2022: 千葉大学, 医学部附属病院, 准教授 2014: 千葉大学医学部附属病院, 臓器制御外科学, 准教授 2011 – 2012: 千葉大学, 医学部附属病院, 講師 2010: 千葉大学, 医学部附属病院, 助教
Review Section/Research Field	Except Principal Investigator General surgery / Basic Section 55010:General surgery and pediatric surgery-related / Biological pharmacy
Keywords	Except Principal Investigator 乳癌 / 乳腺外科学 / 転移性乳癌 / ホスト環境 / 癌幹細胞ニッチ / シナプス / 環境移植 / ALDH1 / Tenascin C / プロテオミクス … More / 細胞間マトリックス / ｾﾝﾁﾈﾙﾘﾝﾊﾟ節 / 有機アニオン輸送ポリペプチド / エストロゲン前駆体 / 乳がん / エストロゲン受容体 / 分子生物学的研究 / トランスポーター / 細胞外マトリックス / 治療抵抗性 / ニッチ / 化学療法抵抗性 / テネイシンC / 癌間質相互作用 / 脂肪細胞 / 非浸潤性乳癌 / バイオマーカ― / 抗体療法 / 遺伝子治療 / 前脂肪細胞 / Luminal type / estrogen signal / breast cancer / animal model / endocrine therapy / 微小管阻害剤 / 抗腫瘍効果 / 増殖抑制効果 / 有害事象 / 新規抗がん剤 Less

in vivoエストロゲン非依存性乳癌細胞株による内分泌療法抵抗性機序の解析研究
- Principal Investigator
  
  山田英幸
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Chiba University
二重機能を有する抗酸化物質による難治性乳癌に対する新たな治療戦略
- Principal Investigator
  
  高田護
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Chiba University
Antibody therapy using gene-transduced adipocytes for breast cancer
- Principal Investigator
  
  Fujimoto Hiroshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Chiba University
Comprehensive gene and protein analysis of ductal carcinoma in situ for novel prognostic biomarkers
- Principal Investigator
  
  Sangai Takafumi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Chiba University
Correlation of Extra cellular matrix as niche to chemo-resistance in breast cancer patients
- Principal Investigator
  
  SAKAKIBARA Masahiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Chiba University
Characterization of cancer-associated adipocytes and evaluation of its role in breast cancer
- Principal Investigator
  
  FUJIMOTO Hiroshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Saitama Medical University
  Chiba University
腫瘍免疫応答を用いた腋窩リンパ節転移陽性乳癌の腋窩ステージング
- Principal Investigator
  
  鈴木ティベリュウ浩志
- Project Period (FY)
  2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Chiba University
Impact of transporters for uptake of estrogen precursors on progression of breast cancer cells
- Principal Investigator
  
  JUN Matsumoto
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Biological pharmacy
- Research Institution
  International University of Health and Welfare
The responsiveness of ALDH1-positive cells to chemotherapy in metastatic lesions and its prognostic significance in patients with breast cancer
- Principal Investigator
  
  SAKAKIBARA Masahiro
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Chiba University

All 2021 2020 2016 2015 2012 Other

All Journal Article Presentation

[Journal Article] Practical approach to prevent COVID-19 infection at breast cancer screening2021
- Author(s)
  Takada Mamoru、Tanaka Gaku、Hashimoto Hideyuki、Hirai Yasuyuki、Fukushima Taichi、Nagashima Takeshi、Otsuka Masayuki、Imazeki Fumio
- Journal Title
  
  Breast Cancer
  
  Volume: 28 Pages: 969-976
- DOI
  10.1007/s12282-021-01235-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16824, KAKENHI-PROJECT-21K08638
[Journal Article] Anti-HER2 antibody therapy using gene-transduced adipocytes for HER2-positive breast cancer2020
- Author(s)
  Takahito Masuda, Hiroshi Fujimoto, Ryotaro Teranaka, Masayuki Kuroda, Yasuyuki, Aoyagi, Takeshi Nagashima, Takafumi Sangai, Mamoru Takada, Ayako, Nakagawa, Yoshitaka Kubota, Koutaro Yokote, Masayuki Ohtsuka
- Journal Title
  
  Breast Cancer Research and Treatment
  
  Volume: 180 Pages: 625-634
- DOI
  10.1007/s10549-020-05581-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08588
[Journal Article] Organic anion transporting polypeptide 2B1 expression correlates with uptake of estrone-3-sulfate and cell proliferation in estrogen receptor-positive breast cancer cells2015
- Author(s)
  Jun Matsumoto, Noritaka Ariyoshi, Masahiro Sakakibara, Takeo Nakanishi, Yoshiyuki Okubo, Nobumitsu Shiina, Kaoru Fujisaki, Takeshi Nagashima, Yukio Nakatani, Ikumi Tamai, Harumi Yamada, Hiroshi Takeda and Itsuko Ishii
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 30 Issue: 2 Pages: 133-141
- DOI
  10.1016/j.dmpk.2014.10.005
- NAID
  210000170465
- ISSN
  1347-4367
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25893224
[Journal Article] Cancer-mediated adipose reversion promotes cancer cell migration via IL-6 and MCP-12015
- Author(s)
  Kaoru Fujisaki,Hiroshi Fujimoto, Takafumi Sangai, Takeshi Nagashima, Masahiro Sakakibara, Nobumitsu Shiina, Masayuki Kuroda, Yasuyuki Aoyagi, Masaru Miyazaki
- Journal Title
  
  Breast Cancer Research and Treatment
  
  Volume: 150 Pages: 255-263
- DOI
  10.1007/s10549-015-3318-2
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461942
[Journal Article] ALDH1-positive cells in axillary lymph node metastases after chemotherapy as a prognostic factor in patients with node-positive breast cancer2012
- Author(s)
  Masahiro Sakakibara, Toshihiko Fujimori, Tetsutaro Miyoshi, Takeshi Nagashima, Hiroshi Fujimoto, Hiroshi Tiberu Suzuki, Yohsuke Ohki, Koya Fushimi, Jissei Yokomizo, Yukio Nakatani and Masaru Miyazaki
- Journal Title
  
  Cancer
  
  Volume: 118(16) Pages: 3899-910
- Data Source
  KAKENHI-PROJECT-22591423
[Presentation] cancer-associated adipocyte (CAA)の特徴と癌進展に果たす役割2016
- Author(s)
  藤本浩司、藤咲薫、三階貴史、長嶋健、榊原雅裕、矢形寛、宮崎勝
- Organizer
  第24回日本乳癌学会学術総会
- Place of Presentation
  東京
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-26461942
[Presentation] Impact of OATP2B1 expression on cell proliferation in ER-positive breast cancer.
- Author(s)
  Jun Matsumoto, Noritaka Ariyoshi, Masahiro Sakakibara, Takeo Nakanishi, Ikumi Tamai, Takeshi Nagashima and Itsuko Ishii.
- Organizer
  10th International ISSX Meeting
- Place of Presentation
  Toronto, Canada
- Data Source
  KAKENHI-PROJECT-25893224
[Presentation] Uptake of an Estrogen Precursor in Estrogen Receptor-Positive Breast Cancer Cells: Focusing on Organic Anion Transporting Polypeptide 2B1
- Author(s)
  Jun Matsumoto, Noritaka Ariyoshi, Masahiro Sakakibara, Takeo Nakanishi, Yoshiyuki Okubo, Nobumitsu Shiina, Kaoru Fujisaki, Yukio Nakatani, Ikumi Tamai, Takeshi Nagashima, Harumi Yamada, Hiroshi Takeda and Itsuko Ishii
- Organizer
  World congress on Pharmacology
- Place of Presentation
  Brisbane, Australia
- Year and Date
  2015-07-20 – 2015-07-22
- Data Source
  KAKENHI-PROJECT-25893224

1. SAKAKIBARA Masahiro (70375632)

# of Collaborated Projects: 6 results

# of Collaborated Products: 6 results
2. FUJIMOTO Hiroshi (60456027)

# of Collaborated Projects: 6 results

# of Collaborated Products: 3 results
3. MIYAZAKI Masaru (70166156)

# of Collaborated Projects: 5 results

# of Collaborated Products: 3 results
4. Sangai Takafumi (00375685)

# of Collaborated Projects: 5 results

# of Collaborated Products: 3 results
5. 大塚将之 (90334185)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
6. 榊原淳太 (20896427)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 高田護 (90800392)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
8. JUN Matsumoto (60709012)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
9. ISHII Itsuko (00202929)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
10. ARIYOSHI Noritaka (00243957)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
11. TAMAI Ikumi (20155237)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
12. NAKANISHI Takeo (30541742)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
13. 鈴木ティベリュウ浩志 (30456032)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 羽山晶子 (80758251)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 岩瀬俊明 (90738254)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 黒田正幸 (00253005)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
17. 窪田吉孝 (10375735)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
18. 山田英幸 (30925102)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. Sato Mamoru

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Nagashima Takeshi 長嶋 健

NAGASHIMA Takeshi 長嶋 健

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[Journal Article] Practical approach to prevent COVID-19 infection at breast cancer screening2021

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[Journal Article] Anti-HER2 antibody therapy using gene-transduced adipocytes for HER2-positive breast cancer2020

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[Journal Article] Organic anion transporting polypeptide 2B1 expression correlates with uptake of estrone-3-sulfate and cell proliferation in estrogen receptor-positive breast cancer cells2015

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[Journal Article] Cancer-mediated adipose reversion promotes cancer cell migration via IL-6 and MCP-12015

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[Journal Article] ALDH1-positive cells in axillary lymph node metastases after chemotherapy as a prognostic factor in patients with node-positive breast cancer2012

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[Presentation] cancer-associated adipocyte (CAA)の特徴と癌進展に果たす役割2016

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Nagashima Takeshi 長嶋健

NAGASHIMA Takeshi 長嶋健