Kuroda Masayuki 黒田正幸

… Alternative Names

Researcher Number	00253005
Other IDs
Affiliation (Current)	2021: 千葉大学, 医学部附属病院, 特任准教授
Affiliation (based on the past Project Information) *help	2013 – 2020: 千葉大学, 医学部附属病院, 特任准教授 2003 – 2006: 高知大学, 医学部, 助手 1999 – 2002: 高知医科大学, 医学部, 助手 1996: Okayama University, Gene Research Center, 遺伝子実験施設, 助手 1994: 岡山大学, 遺伝子実験施設, 助手
Review Section/Research Field	Principal Investigator Virology / Metabolomics / Plastic surgery / Basic Section 56070:Plastic and reconstructive surgery-related Except Principal Investigator Pediatrics / Virology / Basic Section 56070:Plastic and reconstructive surgery-related / Virology / Plastic surgery / Basic Section 55010:General surgery and pediatric surgery-related
Keywords	Principal Investigator 脂肪細胞 / 移植 / アデノウイルスベクター / EBウイルス / 遺伝子治療 / 脂肪幹細胞 / 脂肪組織 / アルツハイマー認知症 / ネプリライシン / アルツハイマー … More Except Principal Investigator dominant-negative EBNA1 / 遺伝子治療 / gene therapy / 脂肪細胞 / エピジェネティクス / ウイルス / 感染症 / Epstein-Barr virus / 上皮細胞 / EBウイルス(EBV) / EBV陽性腫瘍 / Epstein-Barr virus(EBV) / EBウイルス / T / サイトカイン / cytokines / 脂肪移植 / 皮下脂肪 / 癌 / ワクチン / EBV / ペプチドワクチン / CTLエピトープ / 能動輸送 / エネルギー共役 / シンポーター / アンチポーター / 機能部位 / Active transport / Energy coupling / Symporter / Antiporter / Functional domain / BARF0遺伝子 / 細胞悪性化 / 癌化 / BARF0 gene / Epithelial cells / Malignant change / EBV関連腫瘍 / アデノウイルスベクター / アポトーシス / EBV-associated cancers / adenovirus vector / apoptosis / 慢性活動性EBV感染症 / Epstein-Barr virus (EBV) / chronic active EBV infection / 発癌責任遺伝子 / マイクロアレイ / NK細胞腫瘍 / 上皮細胞腫瘍 / NK細胞 / oncogenic genes / microarray / NK cell tumor / epithelial tumor / CTL活性 / Enstein-Barr virus(EBV) / infectious diseases / CTL / 細胞分化 / DNAメチル化 / 皮下脂肪組織 / メチル化 / メタボリックシンドローム / 乳癌 / 抗体療法 / 前脂肪細胞 / アンチエイジング / 機械学習 / シングルセル解析 / 多分化能 / 体性幹細胞 Less

エピジェネティクス編集技術を用いた革新的脂肪移植治療法開発に資する基盤的研究Ongoing
- Principal Investigator
  
  三川信之
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56070:Plastic and reconstructive surgery-related
- Research Institution
  Chiba University
Study on improvement of transplantation efficiency of adipocyte gene therapy product by approach from engrafted cells after transplantationPrincipal InvestigatorOngoing
- Principal Investigator
  
  黒田正幸
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56070:Plastic and reconstructive surgery-related
- Research Institution
  Chiba University
Establishment of epignenetic genome-edited adipocyte for multiple purposesOngoing
- Principal Investigator
  
  窪田吉孝
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56070:Plastic and reconstructive surgery-related
- Research Institution
  Chiba University
遺伝子改変前脂肪細胞を用いた乳癌抗体療法の開発Ongoing
- Principal Investigator
  
  藤本浩司
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Chiba University
Establishment of transport / transplant formulation based on gene expression transition analysis in culture process of cultured preadipocytesPrincipal Investigator
- Principal Investigator
  
  Kuroda Masayuki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Plastic surgery
- Research Institution
  Chiba University
Cellular functional diffrences of adipocytes between superfical and deep subcutaneous fat layer
- Principal Investigator
  
  KUBOTA YOSHITAKA
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Plastic surgery
- Research Institution
  Chiba University
Elucidation of restoration mechanisms in Alzheimer diseases by mobilized stem cells through activation of adipose tissuePrincipal Investigator
- Principal Investigator
  
  KURODA Masayuki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Chiba University
Comprehensive analyses of therapeutic strategy against chronic active Epstein-Barr virus(EBV) infection
- Principal Investigator
  
  WAKIGUCHI Hiroshi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kochi University
小児の難治性EBウイルス感染症に対する効率的ペプチドワクチンの新規開発
- Principal Investigator
  
  細川卓利
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pediatrics
- Research Institution
  Kochi University
Comprehensive analyses of Epstein-Barr virus(EBV) -dependent cellular gene expressions responsible for the viral oncogenesis
- Principal Investigator
  
  IMAI Shosuke
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Kochi University
Novel therapeutic strategy against chronic active Epstein-Barr virus (EBV) infection
- Principal Investigator
  
  WAKIGUCHI Hiroshi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kochi University
Basic research on novel Epstein-Barr virus(EBV)-specific gene therapy against uncontrollable EBV- associated diseases
- Principal Investigator
  
  IMAI Shosuke
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Kochi University
  高知大学(医学部)
EBウイルス特異的治療用アデノウイルスベクターの作製Principal Investigator
- Principal Investigator
  
  黒田正幸
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Virology
- Research Institution
  高知医科大学
Function (s) of a novel Epstein-Barr virus latent gene, BARF0
- Principal Investigator
  
  IMAI Shosuke
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Kochi Medical School
Molecular mechanism of energy coupling in active transport
- Principal Investigator
  
  TSUCHIYA Tomofusa
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Okayama University

All 2020 2019 2018 2017 2006 2005 2004

All Journal Article Presentation Book

[Book] 第3章基質レベルのATP合成に関する酵素,第4章輸送タンパク質,「廣川タンパク質化学第10巻生体エネルギー・光合成」p105-177(土屋友房編)2004
- Author(s)
  土屋友房, 黒田正幸(分担執筆)
- Total Pages
  73
- Publisher
  廣川書店
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590421
[Journal Article] Anti-HER2 antibody therapy using gene-transduced adipocytes for HER2-positive breast cancer2020
- Author(s)
  Takahito Masuda, Hiroshi Fujimoto, Ryotaro Teranaka, Masayuki Kuroda, Yasuyuki, Aoyagi, Takeshi Nagashima, Takafumi Sangai, Mamoru Takada, Ayako, Nakagawa, Yoshitaka Kubota, Koutaro Yokote, Masayuki Ohtsuka
- Journal Title
  
  Breast Cancer Research and Treatment
  
  Volume: 180 Pages: 625-634
- DOI
  10.1007/s10549-020-05581-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08588
[Journal Article] A Novel Approach to the Treatment of Plasma Protein Deficiency: <i>Ex Vivo</i>-Manipulated Adipocytes for Sustained Secretion of Therapeutic Proteins2018
- Author(s)
  Kuroda Masayuki、Saito Yasushi、Aso Masayuki、Yokote Koutaro
- Journal Title
  
  CHEMICAL & PHARMACEUTICAL BULLETIN
  
  Volume: 66 Issue: 3 Pages: 217-224
- DOI
  10.1248/cpb.c17-00786
- NAID
  130006407125
- ISSN
  0009-2363, 1347-5223
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11530, KAKENHI-PROJECT-17K19643
[Journal Article] EBVと冑臨.「特集ヘルペスウイルス学-基礎・臨床研究の進歩-」2006
- Author(s)
  今井章介, 黒田正幸, 石浦嘉人, 小谷典弘
- Journal Title
  
  日本臨床 64(3)
  
  Pages: 651-656
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591190
[Journal Article] EBVと胃癌.「特集ヘルペスウイルス学-基礎・臨床研究の進歩-」2006
- Author(s)
  今井, 章介, 黒田, 正幸, 石浦, 嘉人, 小谷, 典弘
- Journal Title
  
  日本臨床 64(3)
  
  Pages: 651-656
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591190
[Journal Article] H. pylori感染以外の胃癌の成因(3)EBウイルスと胃癌2006
- Author(s)
  今井, 章介, 黒田, 正幸, 松崎, 茂展, 他
- Journal Title
  
  臨床消化器内科 21(8)
  
  Pages: 1125-1132
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591190
[Journal Article] 難治性EBウイルス関連疾患に対する新たな治療戦略2006
- Author(s)
  今井章介, 黒田正幸, 小谷典弘, 松崎茂展
- Journal Title
  
  臨床とウイルス 34(3)
  
  Pages: 158-163
- NAID
  10017657263
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591190
[Journal Article] 難治性EBウイルス関連疾患に対する新たな治療戦略2006
- Author(s)
  今井, 章介, 黒田, 正幸, 小谷, 典弘, 松崎, 茂展
- Journal Title
  
  臨床とウイルス 34(3)
  
  Pages: 158-163
- NAID
  10017657263
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591190
[Journal Article] H. pylori感染以外の胃癌の成因(3)EBウイルスと胃癌2006
- Author(s)
  今井章介, 黒田正幸, 松崎茂展, 他
- Journal Title
  
  臨床消化器内科 21(8)
  
  Pages: 1125-1132
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591190
[Journal Article] 胃発癌に関わる因子とその重み-EBウイルスからの検討2005
- Author(s)
  今井章介, 黒田正幸
- Journal Title
  
  The GI Forefront (印刷中)
- Data Source
  KAKENHI-PROJECT-15590421
[Presentation] 家族性LCAT欠損症を対象としたLCAT遺伝子導入脂肪細胞（LCAT-GMAC）による治療2020
- Author(s)
  黒田正幸、石川耕、前澤善朗、三川信之、窪田吉孝、青栁靖之、浅田咲世、鬼武彰宣、切無澤美香、和田淳、山本徳男、花岡英紀、麻生雅是、齋藤康、横手幸太郎.
- Organizer
  第52回日本動脈硬化学会総会・学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17K11530
[Presentation] Genetically Modified Adipocytes, GMAC, for Regenerative Cell Medicine and Gene Therapy2019
- Author(s)
  Kobayashi N, Kuroda M, Yokote K, Saito Y, Aso M
- Organizer
  5th International Symposium for Medicinal Sciences
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11530
[Presentation] Gene/Cell Therapy for familial LCAT deficiency by Genetically Modified Adipocytes, GMAC.2019
- Author(s)
  Kuroda M, Yamamoto T, Yokote K, Saito Y, Aso M.
- Organizer
  3rd Annual cell therapy World ASIA
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11530
[Presentation] 家族性LACT欠損症に対する脂肪細胞を用いた遺伝子/再生医療技術による難病治療法の実用化研究.2018
- Author(s)
  石川耕、黒田正幸、武城英明、和田淳、麻生雅是、齋藤康、横手幸太郎.
- Organizer
  第50回日本動脈硬化学会総会・学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17K11530
[Presentation] First in human clinical trial of treatment of familial LCAT deficiency syndrome by self-transplantation of therapeutic-enzyme secreting adipocytes.2018
- Author(s)
  Kuroda M, Ishikawa K, Kubota Y, Mitsukawa N, Tawada A, Aoyagi Y, Asada S, Yamamoto T, Konno S, Tanaka S, Tanio M, Aso M, Saito Y, Wada J. Yokote K.
- Organizer
  25th TERMIS (Tissue Engineering and Regenerative Medicine International Society) World Congress.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11530
[Presentation] A novel technology for lifelong treatment of intractable plasma protein deficiency: Ex vivo-manipulated adipocytes for sustained secretion of therapeutic proteins.2018
- Author(s)
  Aoyagi Y, Kuroda M, Asada S, Onitake A, Kirinashizawa M, Yamamoto T, Tanaka S, Konno S, Tanio M, Saito Y, Yokote K, Aso M.
- Organizer
  25th TERMIS (Tissue Engineering and Regenerative Medicine International Society) World Congress.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11530
[Presentation] 家族性LCAT欠損症－腎不全関連異常リポ蛋白の同定とLCAT分泌自己脂肪細胞の移植による持続的LCAT補充療法－2017
- Author(s)
  1)黒田正幸、武城英明、和田淳、石川耕、麻生雅是、齋藤康、横手幸太郎
- Organizer
  第49回日本動脈硬化学会総会・学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17K11530

1. KUBOTA Yoshitaka (10375735)

# of Collaborated Projects: 7 results

# of Collaborated Products: 3 results
2. IMAI Shosuke (60232592)

# of Collaborated Projects: 6 results

# of Collaborated Products: 7 results
3. MAEDA Akihiko (50335931)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. WAKIGUCHI Hiroshi (10116519)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. 三川信之 (40595196)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. 田中知明 (50447299)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. BUJO Hideaki (80291300)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. TSUCHIYA Tomofusa (80012673)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SHIMAMOTO Tadashi (90187443)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. TSUDA Masaaki (80132736)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. MATUMOTO Kenji (60181765)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. FUJIEDA Mikiya (60209020)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 細川卓利 (10380312)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 宇高恵子 (40263066)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 藤本浩司 (60456027)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
16. 三階貴史 (00375685)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
17. 長嶋健 (60292710)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
18. 大塚将之 (90334185)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
19. MALONEY Peter C

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. PETER C. Mal

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 横手幸太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kuroda Masayuki 黒田 正幸

KURODA Masayuki 黒田 正幸

黒田 正幸 クロダ マサユキ

Research Projects

Research Products

Co-Researchers

エピジェネティクス編集技術を用いた革新的脂肪移植治療法開発に資する基盤的研究Ongoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study on improvement of transplantation efficiency of adipocyte gene therapy product by approach from engrafted cells after transplantationPrincipal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of epignenetic genome-edited adipocyte for multiple purposesOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

遺伝子改変前脂肪細胞を用いた乳癌抗体療法の開発Ongoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of transport / transplant formulation based on gene expression transition analysis in culture process of cultured preadipocytesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of restoration mechanisms in Alzheimer diseases by mobilized stem cells through activation of adipose tissuePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

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Research Institution

Principal Investigator

Project Period (FY)

Research Category

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Research Institution

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

EBウイルス特異的治療用アデノウイルスベクターの作製Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Kuroda Masayuki 黒田正幸

KURODA Masayuki 黒田正幸

黒田正幸クロダマサユキ

[Book] 第3章基質レベルのATP合成に関する酵素,第4章輸送タンパク質,「廣川タンパク質化学第10巻生体エネルギー・光合成」p105-177(土屋友房編)2004