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Kuroda Masayuki  黒田 正幸

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… Alternative Names

KURODA Masayuki  黒田 正幸

黒田 正幸  クロダ マサユキ

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Researcher Number 00253005
Other IDs
Affiliation (Current) 2022: 千葉大学, 医学部附属病院, 特任准教授
Affiliation (based on the past Project Information) *help 2013 – 2021: 千葉大学, 医学部附属病院, 特任准教授
2003 – 2006: 高知大学, 医学部, 助手
1999 – 2002: 高知医科大学, 医学部, 助手
1996: Okayama University, Gene Research Center, 遺伝子実験施設, 助手
1994: 岡山大学, 遺伝子実験施設, 助手
Review Section/Research Field
Principal Investigator
Virology / Metabolomics / Plastic surgery / Basic Section 56070:Plastic and reconstructive surgery-related
Except Principal Investigator
Pediatrics / Virology / Basic Section 56070:Plastic and reconstructive surgery-related / Virology / Plastic surgery / Basic Section 55010:General surgery and pediatric surgery-related
Keywords
Principal Investigator
脂肪細胞 / 移植 / アデノウイルスベクター / EBウイルス / 遺伝子治療 / 脂肪幹細胞 / 脂肪組織 / アルツハイマー認知症 / ネプリライシン / アルツハイマー … More / アミロイドβ / アルツハイマー病 / BDNF / 前駆脂肪細胞 / 輸送 / 加工 / 生着率向上 / ex vivo 遺伝子治療 … More
Except Principal Investigator
dominant-negative EBNA1 / 遺伝子治療 / gene therapy / 脂肪細胞 / エピジェネティクス / ウイルス / 感染症 / Epstein-Barr virus / 上皮細胞 / EBウイルス(EBV) / EBV陽性腫瘍 / Epstein-Barr virus(EBV) / EBウイルス / T / サイトカイン / cytokines / 脂肪移植 / DNAメチル化 / 皮下脂肪 / 癌 / ワクチン / EBV / ペプチドワクチン / CTLエピトープ / 能動輸送 / エネルギー共役 / シンポーター / アンチポーター / 機能部位 / Active transport / Energy coupling / Symporter / Antiporter / Functional domain / BARF0遺伝子 / 細胞悪性化 / 癌化 / BARF0 gene / Epithelial cells / Malignant change / EBV関連腫瘍 / アデノウイルスベクター / アポトーシス / EBV-associated cancers / adenovirus vector / apoptosis / 慢性活動性EBV感染症 / Epstein-Barr virus (EBV) / chronic active EBV infection / 発癌責任遺伝子 / マイクロアレイ / NK細胞腫瘍 / 上皮細胞腫瘍 / NK細胞 / oncogenic genes / microarray / NK cell tumor / epithelial tumor / CTL活性 / Enstein-Barr virus(EBV) / infectious diseases / CTL / 細胞分化 / 皮下脂肪組織 / メチル化 / メタボリックシンドローム / 乳癌 / 抗体療法 / 前脂肪細胞 / ヒストン修飾 / 多分化能 / 体性幹細胞 / 分化 / アンチエイジング / 機械学習 / シングルセル解析 Less
  • Research Projects

    (15 results)
  • Research Products

    (18 results)
  • Co-Researchers

    (21 People)
  •  エピジェネティクス編集技術を用いた革新的脂肪移植治療法開発に資する基盤的研究

    • Principal Investigator
      三川 信之
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56070:Plastic and reconstructive surgery-related
    • Research Institution
      Chiba University
  •  Study on improvement of transplantation efficiency of adipocyte gene therapy product by approach from engrafted cells after transplantationPrincipal Investigator

    • Principal Investigator
      黒田 正幸
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56070:Plastic and reconstructive surgery-related
    • Research Institution
      Chiba University
  •  Establishment of epignenetic genome-edited adipocyte for multiple purposes

    • Principal Investigator
      窪田 吉孝
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56070:Plastic and reconstructive surgery-related
    • Research Institution
      Chiba University
  •  Antibody therapy using gene-transduced adipocytes for breast cancer

    • Principal Investigator
      Fujimoto Hiroshi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Chiba University
  •  Establishment of transport / transplant formulation based on gene expression transition analysis in culture process of cultured preadipocytesPrincipal Investigator

    • Principal Investigator
      Kuroda Masayuki
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Plastic surgery
    • Research Institution
      Chiba University
  •  Cellular functional diffrences of adipocytes between superfical and deep subcutaneous fat layer

    • Principal Investigator
      KUBOTA YOSHITAKA
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Plastic surgery
    • Research Institution
      Chiba University
  •  Elucidation of restoration mechanisms in Alzheimer diseases by mobilized stem cells through activation of adipose tissuePrincipal Investigator

    • Principal Investigator
      KURODA Masayuki
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Chiba University
  •  Comprehensive analyses of therapeutic strategy against chronic active Epstein-Barr virus(EBV) infection

    • Principal Investigator
      WAKIGUCHI Hiroshi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Kochi University
  •  小児の難治性EBウイルス感染症に対する効率的ペプチドワクチンの新規開発

    • Principal Investigator
      細川 卓利
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Pediatrics
    • Research Institution
      Kochi University
  •  Comprehensive analyses of Epstein-Barr virus(EBV) -dependent cellular gene expressions responsible for the viral oncogenesis

    • Principal Investigator
      IMAI Shosuke
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Virology
    • Research Institution
      Kochi University
  •  Novel therapeutic strategy against chronic active Epstein-Barr virus (EBV) infection

    • Principal Investigator
      WAKIGUCHI Hiroshi
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Kochi University
  •  Basic research on novel Epstein-Barr virus(EBV)-specific gene therapy against uncontrollable EBV- associated diseases

    • Principal Investigator
      IMAI Shosuke
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Virology
    • Research Institution
      Kochi University
      高知大学(医学部)
  •  EBウイルス特異的治療用アデノウイルスベクターの作製Principal Investigator

    • Principal Investigator
      黒田 正幸
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Virology
    • Research Institution
      高知医科大学
  •  Function (s) of a novel Epstein-Barr virus latent gene, BARF0

    • Principal Investigator
      IMAI Shosuke
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Virology
    • Research Institution
      Kochi Medical School
  •  Molecular mechanism of energy coupling in active transport

    • Principal Investigator
      TSUCHIYA Tomofusa
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Okayama University

All 2020 2019 2018 2017 2006 2005 2004

All Journal Article Presentation Book

  • [Book] 第3章 基質レベルのATP合成に関する酵素,第4章 輸送タンパク質,「廣川タンパク質化学 第10巻 生体エネルギー・光合成」p105-177(土屋友房編)2004

    • Author(s)
      土屋友房, 黒田正幸(分担執筆)
    • Total Pages
      73
    • Publisher
      廣川書店
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590421
  • [Journal Article] Anti-HER2 antibody therapy using gene-transduced adipocytes for HER2-positive breast cancer2020

    • Author(s)
      Takahito Masuda, Hiroshi Fujimoto, Ryotaro Teranaka, Masayuki Kuroda, Yasuyuki, Aoyagi, Takeshi Nagashima, Takafumi Sangai, Mamoru Takada, Ayako, Nakagawa, Yoshitaka Kubota, Koutaro Yokote, Masayuki Ohtsuka
    • Journal Title

      Breast Cancer Research and Treatment

      Volume: 180 Pages: 625-634

    • DOI

      10.1007/s10549-020-05581-x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K08588
  • [Journal Article] A Novel Approach to the Treatment of Plasma Protein Deficiency: <i>Ex Vivo</i>-Manipulated Adipocytes for Sustained Secretion of Therapeutic Proteins2018

    • Author(s)
      Kuroda Masayuki、Saito Yasushi、Aso Masayuki、Yokote Koutaro
    • Journal Title

      CHEMICAL & PHARMACEUTICAL BULLETIN

      Volume: 66 Issue: 3 Pages: 217-224

    • DOI

      10.1248/cpb.c17-00786

    • NAID

      130006407125

    • ISSN
      0009-2363, 1347-5223
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K11530, KAKENHI-PROJECT-17K19643
  • [Journal Article] EBVと冑臨.「特集ヘルペスウイルス学-基礎・臨床研究の進歩-」2006

    • Author(s)
      今井 章介, 黒田 正幸, 石浦 嘉人, 小谷 典弘
    • Journal Title

      日本臨床 64(3)

      Pages: 651-656

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591190
  • [Journal Article] EBVと胃癌.「特集ヘルペスウイルス学-基礎・臨床研究の進歩-」2006

    • Author(s)
      今井, 章介, 黒田, 正幸, 石浦, 嘉人, 小谷, 典弘
    • Journal Title

      日本臨床 64(3)

      Pages: 651-656

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591190
  • [Journal Article] H. pylori感染以外の胃癌の成因(3)EBウイルスと胃癌2006

    • Author(s)
      今井, 章介, 黒田, 正幸, 松崎, 茂展, 他
    • Journal Title

      臨床消化器内科 21(8)

      Pages: 1125-1132

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591190
  • [Journal Article] 難治性EBウイルス関連疾患に対する新たな治療戦略2006

    • Author(s)
      今井 章介, 黒田 正幸, 小谷 典弘, 松崎 茂展
    • Journal Title

      臨床とウイルス 34(3)

      Pages: 158-163

    • NAID

      10017657263

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591190
  • [Journal Article] 難治性EBウイルス関連疾患に対する新たな治療戦略2006

    • Author(s)
      今井, 章介, 黒田, 正幸, 小谷, 典弘, 松崎, 茂展
    • Journal Title

      臨床とウイルス 34(3)

      Pages: 158-163

    • NAID

      10017657263

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591190
  • [Journal Article] H. pylori感染以外の胃癌の成因(3)EBウイルスと胃癌2006

    • Author(s)
      今井 章介, 黒田 正幸, 松崎 茂展, 他
    • Journal Title

      臨床消化器内科 21(8)

      Pages: 1125-1132

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591190
  • [Journal Article] 胃発癌に関わる因子とその重み-EBウイルスからの検討2005

    • Author(s)
      今井章介, 黒田正幸
    • Journal Title

      The GI Forefront (印刷中)

    • Data Source
      KAKENHI-PROJECT-15590421
  • [Presentation] 家族性LCAT欠損症を対象としたLCAT遺伝子導入脂肪細胞(LCAT-GMAC)による治療2020

    • Author(s)
      黒田正幸、石川耕、前澤善朗、三川信之、窪田吉孝、青栁靖之、浅田咲世、鬼武彰宣、切無澤美香、和田淳、山本徳男、花岡英紀、麻生雅是、齋藤康、横手幸太郎.
    • Organizer
      第52回日本動脈硬化学会総会・学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K11530
  • [Presentation] LCAT遺伝子導入脂肪細胞(LCAT-GMAC)による家族性LCAT欠損症の治療2020

    • Author(s)
      黒田 正幸、石川 耕、前澤 善朗、三川 信之、窪田 吉孝、青栁 靖之、浅田 咲世、鬼武 彰宣、切無澤 美香、和田 淳、山本 徳男、花岡 英紀、麻生 雅是、齋藤 康、横手 幸太郎
    • Organizer
      第52回日本動脈硬化学会総会・学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K09859
  • [Presentation] Genetically Modified Adipocytes, GMAC, for Regenerative Cell Medicine and Gene Therapy2019

    • Author(s)
      Kobayashi N, Kuroda M, Yokote K, Saito Y, Aso M
    • Organizer
      5th International Symposium for Medicinal Sciences
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11530
  • [Presentation] Gene/Cell Therapy for familial LCAT deficiency by Genetically Modified Adipocytes, GMAC.2019

    • Author(s)
      Kuroda M, Yamamoto T, Yokote K, Saito Y, Aso M.
    • Organizer
      3rd Annual cell therapy World ASIA
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11530
  • [Presentation] 家族性LACT欠損症に対する脂肪細胞を用いた遺伝子/再生医療技術による難病治療法の実用化研究.2018

    • Author(s)
      石川耕、黒田正幸、武城英明、和田淳、麻生雅是、齋藤康、横手幸太郎.
    • Organizer
      第50回日本動脈硬化学会総会・学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K11530
  • [Presentation] First in human clinical trial of treatment of familial LCAT deficiency syndrome by self-transplantation of therapeutic-enzyme secreting adipocytes.2018

    • Author(s)
      Kuroda M, Ishikawa K, Kubota Y, Mitsukawa N, Tawada A, Aoyagi Y, Asada S, Yamamoto T, Konno S, Tanaka S, Tanio M, Aso M, Saito Y, Wada J. Yokote K.
    • Organizer
      25th TERMIS (Tissue Engineering and Regenerative Medicine International Society) World Congress.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11530
  • [Presentation] A novel technology for lifelong treatment of intractable plasma protein deficiency: Ex vivo-manipulated adipocytes for sustained secretion of therapeutic proteins.2018

    • Author(s)
      Aoyagi Y, Kuroda M, Asada S, Onitake A, Kirinashizawa M, Yamamoto T, Tanaka S, Konno S, Tanio M, Saito Y, Yokote K, Aso M.
    • Organizer
      25th TERMIS (Tissue Engineering and Regenerative Medicine International Society) World Congress.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11530
  • [Presentation] 家族性LCAT欠損症-腎不全関連異常リポ蛋白の同定とLCAT分泌自己脂肪細胞の移植による持続的LCAT補充療法-2017

    • Author(s)
      1)黒田正幸、武城英明、和田淳、石川耕、麻生雅是、齋藤康、横手幸太郎
    • Organizer
      第49回日本動脈硬化学会総会・学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K11530
  • 1.  KUBOTA Yoshitaka (10375735)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 4 results
  • 2.  IMAI Shosuke (60232592)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 7 results
  • 3.  MAEDA Akihiko (50335931)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  WAKIGUCHI Hiroshi (10116519)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  三川 信之 (40595196)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  田中 知明 (50447299)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  BUJO Hideaki (80291300)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  TSUCHIYA Tomofusa (80012673)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  SHIMAMOTO Tadashi (90187443)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  TSUDA Masaaki (80132736)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  MATUMOTO Kenji (60181765)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  FUJIEDA Mikiya (60209020)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  Fujimoto Hiroshi (60456027)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 14.  細川 卓利 (10380312)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  宇高 恵子 (40263066)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  三階 貴史 (00375685)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 17.  長嶋 健 (60292710)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 18.  大塚 将之 (90334185)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 19.  MALONEY Peter C
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  PETER C. Mal
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  横手 幸太郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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