TSUCHIYA Tomofusa 土屋友房

Researcher Number	80012673
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2012: 立命館大学, 薬学部, 教授 2008 – 2010: Okayama University, 大学院・医歯薬学総合研究科, 教授 2006: Okayama University, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 大学院医歯薬学総合研究科, 教授 2005 – 2006: 岡山大学, 大学院・医歯薬学総合研究科, 教授 2004: 岡山大学, 薬学部, 教授 … More 1986 – 2002: 岡山大学, 薬学部, 教授 1986: 岡山大, 薬学部, 教授 1985: 岡山大学, 薬, 助教授 Less
Review Section/Research Field	Principal Investigator Biological pharmacy / Environmental pharmacy / Bacteriology (including Mycology) / 物質生物化学 Except Principal Investigator Biological pharmacy / Biological pharmacy / 医学一般
Keywords	Principal Investigator カチオン共役 / 腸炎ビブリオ / ATPase / 能動輸送 / アンチポーター / DnaA / ATP / MRSA / Active transport / シンポーター … More / 構造と機能 / ORC / DNA複製 / 多剤耐性菌 / 多剤排出ポンプ / 遺伝子 / Cation coupling / Symporter / Antiporter / Functional domain / 黄色ブドウ球菌 / イオン輸送系 / 緑膿菌 / ADP / 機能ドメイン / 一次構造 / Primary structure / アデノシン輸送 / フォルマイシン / セリン感受性 / pH感受性 / 遺伝子群 / ロダネ-ゼ / 大腸菌 / エネルギ-転換 / ATP合成 / 共役系 / イオン / トランスポータ / チャネル / シンポータ / アンチポ-タ / クローニング / CdC6p / 制御 / 試験管内 / 耐性系 / 医薬品開発 / 抗菌薬 / バイオフィルム形成阻害 / VRE / 抗菌物質 / バイオフィルム阻害物質 / 耐性菌 / 抗MRSA作用 / カチオン / 【Na^+】 / 【H^+】 / 輸送機構 / 輸送タンパク質 / 輸送制御 / 輸送系の構造 / Transport mechanism / Transport protein / Transport regulation / セリン / 生育阻害 / Serine / Growth inhibition / Genes / エネルギー共役 / 機能部位 / Energy coupling / Na+輸送系 / 耐塩性 / Na_+輸送系 / イオン輸送 / Vibro parahaemolyticus / Staphylococcus aureus / Na^+ transport system / halotorelance / antiporter / ion transport system / 能動輸送系 / 統一性と多様性 / シンポート系 / アンチポート系 / Structure and function / Unity and diversity / 薬剤排出系 / パッチクランプ / Drug extrusion system / Ion transport / Pseudomonas aeruginosa / Vibrio parahaemolyticus / Patch clamp / 活性調節 / リン脂質 / 酸性リン脂質 / 結晶構造解析 / 癌 / 開始因子 / ATP結合 / Cdc6p / DNA replication / regulation of activity / 全体像の解析 / 排出ポンプ阻害剤 / 肺炎桿菌 / スカイリン / 排出ポンプ阻害物質 / 感染症 / 抗生物質 / 耐性系阻害薬 / 系統的解析 / ポンプ阻害剤 / 有効物質 / multidrug resistant bacteria / multidrug efflux pump / P.aeruginosa / analysis of total picture / inhibitor of efflux pump / K.pneumoniae / skyrin / 輸送担体 / アミノ酸置換 / 機能変化 / 一次構造の変化 / 機能の変化 / 変異の同定 / Transport carrier / Amino acid substitution / Changes in function / 遺伝子解析 / ナトリウム … More Except Principal Investigator スルホロブス / 鉄酸化細菌 / ハロバクテリア / アーキロドプシン / 腸炎ビブリオ / H^+ATPアーゼ / ベン毛モーター / 遺伝子導入 / 液胞 / H^+ ATPアーゼ / H^+ PPiアーゼ / チトクロム酸化酵素 / DNA複製 / 癌 / 開始因子 / ATP結合 / ATPase / DnaA / ORC / Cdc6p / 細胞生物学 / 多剤排出ポンプ / 肺炎桿菌 / RND / 多剤耐性菌 / ハロバクタリア / Na^+排出型呼吸鎖 / チトクロムc-552 / バクテリオロドプシン / イオンチャネル / 水チャネル / トランスポータ / カルシウムポンプ / 構造・機能相関 / クローニング / ion channel / water channel / transporter / Ca pump / structure-function relation / cloning / 神経突起伸長 / シナプス形成 / 遺伝子発現 / リボプローブによるmRNA定量 / プロテインキナーゼ阻害剤 / トランスフェクション / レトロウイルスベクター / 脳内への外来遺伝子導入 / マウス脳cDNAバンク / 脳特異的cDNA / 脳内遺伝子発現 / 脳内mRNA定量 / RNA-RNAハイブリダイゼーション / 遺伝子発現制御 / 神経系ネットワーク / Neurite extension / Synapse formation / Gene expression / Specific mRNA quantitation / Riboprobes / Transfection / レトロウイルス / 細胞移植 / 小脳初代細胞 / 小脳 / ベクター / 中枢神経系 / 移植 / ウイルス感染 / 神経疾患治療 / Retrovirus-mediated gene transfer / Cerebellum / Primary culture / Transplantation / Gene therapy Less

Identification of multidrug resistance mechanisms in Klebsiella pneumoniae and analysis of the function of these gene products.
- Principal Investigator
  
  OGAWA Wakano
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Okayama University
Analysis of multidrug resistance systems in multidrug resistant bacteria and development of drugs effective on the resistant bacteriaPrincipal Investigator
- Principal Investigator
  
  TSUCHIYA Tomofusa
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental pharmacy
- Research Institution
  Okayama University
Systematic analysis of multidrug efflux pumps in multidrug resistant bacteria and development of pump inhibitorPrincipal Investigator
- Principal Investigator
  
  TSUCHIYA Tomofusa
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  OKYAMA UNIVERSITY
ガン化に伴うDNA複製開始制御の変化と、その抗がん剤の新規ターゲットとしての応用Principal Investigator
- Principal Investigator
  
  土屋友房
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Okayama University
複製開始蛋白質DnaAのX線結晶構造解析による高次構造の決定と機能部位解析
- Principal Investigator
  
  黒田照夫
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Okayama University
Tne initiator of chromosomal DNA replication in E. coli.Principal Investigator
- Principal Investigator
  
  TSUCHIYA Tomofusa, 黒田照夫
- Project Period (FY)
  1999 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  OKAYAMA UNIVERSITY
Unity and diversity in active transport in cell membransPrincipal Investigator
- Principal Investigator
  
  TSUCHIYA Tomofusa
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  Biological pharmacy
- Research Institution
  Okayama University
Structure and function of drug- and ion-extrusion systems in bacteriaPrincipal Investigator
- Principal Investigator
  
  TSUCHIYA Tomofusa
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  OKAYAMA UNIVERSITY
イオン駆動型トランスポーターとチャネルの構造・機能協関Principal Investigator
- Principal Investigator
  
  土屋友房
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Okayama University
Channel-Transporter Correlation
- Principal Investigator
  
  OKADA Yasunobu
- Project Period (FY)
  1995 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Okazaki National Research Institutes
Characteristics of ion tranport systems in Vibrio parahaemolyticus and Staphylococcus aureusPrincipal Investigator
- Principal Investigator
  
  TSUCHIYA Tomofusa
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Okayama University
Molecular mechanism of energy coupling in active transportPrincipal Investigator
- Principal Investigator
  
  TSUCHIYA Tomofusa
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Okayama University
Na^+/H^+アンチポーターとNa^+/H^+/基質シンポーターの共役系の解析Principal Investigator
- Principal Investigator
  
  土屋友房
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Okayama University
Structure and mechanism in cation-coupled transport systemsPrincipal Investigator
- Principal Investigator
  
  TSUCHIYA Tomofusa
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Okayama University
Analysis of factors involved in serine-sensitivity in bacterial cellsPrincipal Investigator
- Principal Investigator
  
  TSUCHIYA Tomofusa
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Okayama University
大腸菌のセリン感受性とpH感受性に関与する遺伝子群の解析Principal Investigator
- Principal Investigator
  
  土屋友房
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Okayama University
腸炎ビブリオのエネルギ-転系の特殊性Principal Investigator
- Principal Investigator
  
  土屋友房
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Okayama University
腸炎ビブリオ細胞膜におけるアデノシン・フォルマイシン輸送系の解析Principal Investigator
- Principal Investigator
  
  土屋友房
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Okayama University
異環境生物のエネルギー
- Principal Investigator
  
  向畑恭男
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Nagoya University
異環境生物のエネルギー
- Principal Investigator
  
  向畑恭男
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
Structure and mechanism in active transport systems for sugars, amino acids and ions.Principal Investigator
- Principal Investigator
  
  TSUCHIYA Tomofusa
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Okayama University
異環境生物のエネルギー
- Principal Investigator
  
  向畑恭男
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
Application of retrovirus-mediated gene transfer and cell transplantation for studying the structure and function of nervous systems at the level of gene action
- Principal Investigator
  
  TSUDA Masaaki
- Project Period (FY)
  1987 – 1989
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  医学一般
- Research Institution
  Okayama University, Faculty of Pharmaceutical Sciences
Approaches to study the structure and function of nervous systems at the level of gene expression
- Principal Investigator
  
  TSUDA Masaaki
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Okayama University, Fuculty of Pharmaceutlcal Sciences
Alterations in the primary structure of the active transport carrier and changes in the functionPrincipal Investigator
- Principal Investigator
  
  TSUCHIYA Tomofusa
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  物質生物化学
- Research Institution
  Okayama University
カチオン輸送蛋白質のカチオン認識機構に関する遺伝子工学的解析Principal Investigator
- Principal Investigator
  
  土屋友房
- Project Period (FY)
  1985
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Okayama University

All 2013 2012 2011 2010 2009 2008 2005 2004

All Journal Article Presentation Patent

[Journal Article] Functionally cloned pdrM from Streptococcus pneumoniae encodes a Na+ coupled multidrug efflux pump2013
- Author(s)
  Hashimoto K, Ogawa W, Nishioka T, Tsuchiya T, Kuroda T
- Journal Title
  
  PLoS One
  
  Volume: 8(3)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590064
[Journal Article] Functionally cloned pdrM from Streptococcus pneumoniae encodes a Na+ coupled multidrug efflux pump.2013
- Author(s)
  Hashimoto K, Ogawa W, Nishioka T, Tsuchiya T, Kuroda T
- Journal Title
  
  PLoS One
  
  Volume: 8(3)
- DOI
  10.1371/journal.pone.0059525
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590064
[Journal Article] Functional study of the novel multidrug efflux pump KexD from Klebsiella pneumoniae.2012
- Author(s)
  Ogawa W, Onishi M, Ni R, Tsuchiya T, Kuroda T
- Journal Title
  
  Gene
  
  Volume: 498(2) Pages: 177-182
- DOI
  10.1016/j.gene.2012.02.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590064
[Journal Article] Functional study of the novel multidrug efflux pump KexD from Klebsiella pneumoniae2012
- Author(s)
  Ogawa W, Onishi M, Ni R, Tsuchiya T, Kuroda T
- Journal Title
  
  Gene
  
  Volume: 498(2) Pages: 177-82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590064
[Journal Article] Quercetin diacylglycoside analogues showing dual inhibition of DNA gyrase and topoisomerase IV as novel antibacterial agents2011
- Author(s)
  Hossion AM, Zamami y Kandahary RK, Tsuchiya T, Ogawa W, Iwado A, Sasaki K
- Journal Title
  
  J Med Chem
  
  Volume: 54 Pages: 3686-3703
- DOI
  10.1021/jm200010x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590064
[Journal Article] Design, synthesis, and biological evaluation of a novel series of quercetin diacylglucosides as potent anti-MRSA and anti-VRE agents.2010
- Author(s)
  Hossion, A.M., N.Otsuka, R.K.Kandahary, T.Tsuchiya, W.Ogawa, A.Iwado, Y.Zamami, K.Sasaki.
- Journal Title
  
  Bioorg.Med.Chem.Lett. 20
  
  Pages: 5349-5352
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590120
[Journal Article] Design, synthesis, and biological evaluation of a novel series of quercetin diacylglucosides as potent anti-MRSA and anti-VRE agents.2010
- Author(s)
  Hossion AM, Otsuka N, Kandahary RK, Tsuchiya T, Ogawa W, Iwado A, Zamami Y, Sasaki K.
- Journal Title
  
  Bioorg Med Chem Lett.
  
  Volume: 20 Pages: 5349-5352
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590064
[Journal Article] Gene cloning and characterization of EfmA, a multidrug efflux pump, from Enterococcus faecium.2009
- Author(s)
  Nishioka, T., W.Ogawa, T.Kuroda, T.Katsu, T.Tsuchiya.
- Journal Title
  
  Biol.Pharm.Bull. 32
  
  Pages: 483-488
- NAID
  110007122697
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590120
[Journal Article] Gene cloning and characteristics of the RND-type multidrug efflux pump MuxABC-OpmB possessing two RND components in Pseudomonas aeruginosa.2009
- Author(s)
  Mima, T., N.Kohira, Y.Li, H.Sekiya, W.Ogawa, T.Kuroda, T.Tsuchiya.
- Journal Title
  
  Microbiology 155
  
  Pages: 3509-3517
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590120
[Journal Article] Effect of natural polyphenols on methicillin-resistant Staphylococcus aureus in relation to their chemical and physical properties.2009
- Author(s)
  Hatano, T., M.Kusuda, M.Tsugawa, S.Taniguchi, T.Tsuchiya, T.Yoshida.
- Journal Title
  
  Phytochem.Res.
  
  Pages: 31-47
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590120
[Journal Article] Synergistic effect of kaempferol glycosides purified from Laurus nobilis and fluoroquinolones on methicillin-resistant Staphylococcus aureus.2009
- Author(s)
  Liu, M.H., N.Otsuka, K.Noyori, S.Shiota, W.Ogawa, T.Kuroda, T.Hatano, T.Tsuchiya.
- Journal Title
  
  Biol.Pharm.Bull. 32
  
  Pages: 489-492
- NAID
  110007122695
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590120
[Journal Article] Enhancement of antibacterial effects of epigallocatechin gallate, using ascorbic acid.2008
- Author(s)
  Hatano, T., M.Tsugawa, M.Kusuda, S.Taniguchi, T.Yoshida, S.Shiota, T.Tsuchiya.
- Journal Title
  
  Phytochemistry 69
  
  Pages: 3111-3116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590120
[Journal Article] Anti-methicillin resistant Staphylococcus aureus (MRSA) compounds isolated from Laurus nobilis.2008
- Author(s)
  Otsuka, N., M.H.Liu, S.Shiota, W.Ogawa, T.Kuroda, T.Hatano, T.Tsuchiya.
- Journal Title
  
  Biol.Pharm.Bull. 31
  
  Pages: 1794-1797
- NAID
  110006878971
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590120
[Journal Article] Functional gene cloning and characterization of the SsmE multidrug efflux pump from Serratia marcescens.2008
- Author(s)
  Minato, Y., F.Shahcheraghi, W.Ogawa, T.Kuroda, T.Tsuchiya.
- Journal Title
  
  Biol.Pharm.Bull. 31
  
  Pages: 516-519
- NAID
  110006623085
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590120
[Journal Article] Identification of essential amino acid residues of the NorM Na+/multidrug antipoter in Vibrio parahaemolyticus2005
- Author(s)
  Masato Otsuka, Tomofusa Tsuchiya 外
- Journal Title
  
  J.Bacteriol. 187
  
  Pages: 1552-1558
- Data Source
  KAKENHI-PROJECT-16390131
[Journal Article] Remarkable synergies between baicalein and tetracycline, and baicaleir and β-lactams against methicillin-resistant Staphylococcus aureus2005
- Author(s)
  Mai Fujita, Tomofusa Tsuchiya 外
- Journal Title
  
  Microbiol.Immunol. (In press)
- Data Source
  KAKENHI-PROJECT-16390131
[Journal Article] Mechanisms of action of corilagin and tellimagrandin I that remarkably potentiate the activity of β-lactams against methicillin-resistant Staphylococcus aureus2004
- Author(s)
  Sumiko Shiota, Tomofusa Tsuchiya 外
- Journal Title
  
  Microbiol.Immunol. 48
  
  Pages: 67-73
- NAID
  50000379722
- Data Source
  KAKENHI-PROJECT-16390131
[Journal Article] A major Li^+ extrusion system NhaB of Pseudomonas aeruginosa : Comparison with the major Na^+ extrusion system NhaP2004
- Author(s)
  Teruo Kuroda, Tomofusa Tsuchiya 外
- Journal Title
  
  Microbiol.Immunol. 48
  
  Pages: 243-250
- NAID
  10012840106
- Data Source
  KAKENHI-PROJECT-16390131
[Patent] バイオフィルム形成阻害剤2010
- Inventor(s)
  土屋友房、塩田澄子
- Industrial Property Rights Holder
  土屋友房、塩田澄子
- Filing Date
  2010-05-04
- Overseas
- Data Source
  KAKENHI-PROJECT-20590120
[Patent] バイオフィルム形成阻害剤2009
- Inventor(s)
  土屋友房、塩田澄子
- Industrial Property Rights Holder
  土屋友房、塩田澄子
- Filing Date
  2009-04-13
- Data Source
  KAKENHI-PROJECT-20590120
[Presentation] 多剤耐性緑膿菌の出現と抗菌薬曝露の関係2013
- Author(s)
  藤岡孝浩,保田菜美,土屋友房,小川和加野,黒田照夫
- Organizer
  第86回日本細菌学会総会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-22590064
[Presentation] Serratia marcescensにおける新規消毒薬耐性因子の解析2013
- Author(s)
  峠雄太,小川和加野,土屋友房,後藤直正,黒田照夫
- Organizer
  第86回日本細菌学会総会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-22590064
[Presentation] Serratia marcescensの消毒薬クロルヘキシジンに対する耐性機構の解析2012
- Author(s)
  芳賀仁美、峠雄太、朝熊弘樹、小川和加野、後藤直正、土屋友房、黒田照夫
- Organizer
  第24回微生物シンポジウム
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22590064
[Presentation] 肺炎桿菌のMATE型多剤排出ポンプKrtM、DinF、YeeOの解析2012
- Author(s)
  堂段駿太、高桂鳳、岸野孝則、大西元康、土屋友房、黒田照夫、小川和加野
- Organizer
  第85回日本細菌学会総会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-22590064
[Presentation] Isolation and analysis of Klebsiella pneumoniae ATCC10031 multidrug resistant mutants2012
- Author(s)
  W. Ogawa, R. Ni, M. Mizusawa, M. Onishi, R. Kitagawa, T. Tsuchiya, and T. Kuroda
- Organizer
  II International Conference on Antimicrobial Research
- Place of Presentation
  Lisbon, Portugal
- Data Source
  KAKENHI-PROJECT-22590064
[Presentation] 大腸菌Giant Protoplastにおける新規大量発現系の構築2012
- Author(s)
  三上太郎、中村浩二、村井美知子、谷聖人、小川和加野、土屋友房、矢部勇、黒田照夫
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  博多
- Data Source
  KAKENHI-PROJECT-22590064
[Presentation] 多剤耐性肺炎桿菌 Oxa128株における RND型排出ポンプOqxABの解析2012
- Author(s)
  北川良子,倪蕊〓,大西元康,土屋友房,小川和加野,黒田照夫
- Organizer
  第65回日本細菌学会中国・四国支部総会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-22590064
[Presentation] 多剤耐性緑膿菌の分離及びその耐性メカニズムの解析2012
- Author(s)
  保田菜美、藤岡孝浩、藤田智子、土屋友房、小川和加野、黒田照夫
- Organizer
  第85回日本細菌学会総会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-22590064
[Presentation] 多剤耐性緑膿菌の分離及びその耐性メカニズムの解析2012
- Author(s)
  保田菜美、藤岡孝浩、藤田智子、土屋友房、小川和加野、黒田照夫
- Organizer
  第65回日本細菌学会中国・四国支部総会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-22590064
[Presentation] 肺炎桿菌のMATE型多剤排出ポンプKrtM、DinF2012
- Author(s)
  堂段駿太、高桂鳳、岸野孝則、大西元康、土屋友房、黒田照夫、小川和加野
- Organizer
  YeeOの解析(第85回日本細菌学会総会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-22590064
[Presentation] NA^+ TOLERANCE MECHANISM IN HALOPHILIC VIBRIO PAEAHAEMOLYTICUS2011
- Author(s)
  Teruo Kuroda, Yu Nagira, KiyohitoTani', Seiji Kojim, Mari Okuno, Makoto Miyazawa, Wakano Ogawa, Tomofusa Tsuchiya
- Organizer
  IUMS 2011
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22590064
[Presentation] Functional study of RND-type multidrug efflux pump KexD from Klebsiella pneumoniae2011
- Author(s)
  Wakano Ogawa, Motoyasu Onishi, Rui-ting Ni, Teruo Kuroda, and Tomofusa Tsuchiya
- Organizer
  IUMS2011
- Place of Presentation
  Sapporo, Japan
- Data Source
  KAKENHI-PROJECT-22590064
[Presentation] ブドウ球菌によるバイオフィルム形成能および安全性に対する高分子膜中の各種テルペノイドの影響について2011
- Author(s)
  塩田澄子、山田陽一、大塚智恵、内田多恵子、小川和加野、黒田照夫、土屋友房
- Organizer
  第56回ブドウ球菌研究会
- Place of Presentation
  高知
- Data Source
  KAKENHI-PROJECT-22590064
[Presentation] ブドウ球菌属によるバイオフィルム産生を抑制する物質2011
- Author(s)
  塩田澄子、大塚智恵、内田多恵子、山田陽一、小川和加野、黒田照夫、土屋友房
- Organizer
  第23回微生物シンポジウム
- Place of Presentation
  銚子、千葉
- Data Source
  KAKENHI-PROJECT-22590064
[Presentation] CLONING AND CHAEACTERIZATION OF WMA, A MULTIDRUG EFFLUX PUMP FROM VIBRIO VULNIFICUS2011
- Author(s)
  Eun-Woo Lee, Tae-Hwan Byun, Do-Kyun Kim, Young-Mog Kim, Myung-Suk Lee, Byung-Woo Kim, Wakano Ogawa, Teruo Kuroda, Tomofusa Tsuchiya
- Organizer
  IUMS 2011
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22590064
[Presentation] 肺炎桿菌の多剤耐性変異株の分離とその解析2011
- Author(s)
  小川和加野、水澤実名子、Ni Ruiting、大西元康、土屋友房、黒田照夫
- Organizer
  第33回生体膜と薬物の総合作用シンポジウム
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-22590064
[Presentation] Functional study of RND-type multidrug efflux pump KexD from Klebsiella pneumoniae2011
- Author(s)
  Wakano Ogawa, Motoyasu Onishi, Rui-ting Ni, Teruo Kuroda, Tomofusa Tsuchiya
- Organizer
  IUMS2011
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22590064
[Presentation] 肺炎桿菌のRND型多剤排出ポンプAcrABの性質2010
- Author(s)
  水澤実名子, 大西元康, 倪蕊〓, 小川和加野, 黒田照夫, 土屋友房
- Organizer
  第63回日本細菌学会中国・四国支部総会
- Place of Presentation
  愛媛県松山市
- Data Source
  KAKENHI-PROJECT-22590064
[Presentation] 肺炎桿菌のRND型多剤排出ポンプAcrABの性質2010
- Author(s)
  水澤実名子, 大西元康, 倪蕊〓, 小川和加野, 黒田照夫, 土屋友房
- Organizer
  第63回日本細菌学会中国・四国支部総会
- Place of Presentation
  松山
- Data Source
  KAKENHI-PROJECT-22590064
[Presentation] Novel 2",3",4",6"-o-substituted quercetin-3-o-galactosides and glucosides analogous as potent anti-MRSA and anti-VRE agents : Design, synthesis, sar and in-vitro assessment2010
- Author(s)
  Abugafar M.L.Hossion, Rafiya K.Kandahary, Tomofusa Tsuchiya, Wakano Ogawa, Yoshito Zamami, Kenji Sasakia
- Organizer
  XXIVth European Colloquium on Heterocyclic Chemistry (ECHC-2010)
- Place of Presentation
  Vienna University of Technology Vienna (Austria)
- Data Source
  KAKENHI-PROJECT-22590064
[Presentation] Serratia marcescensの消毒薬耐性系の解析2010
- Author(s)
  朝熊弘樹、芳賀仁美、小川和加野, 黒田照夫、後藤直正、土屋友房
- Organizer
  XXIVth European Colloquium on Heterocyclic Chemistry (ECHC-2010)
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22590064
[Presentation] 腸炎ビブリオのNa+耐性機構2010
- Author(s)
  柳樂優, 谷聖人, 宮澤誠, 小川和加野, 土屋友房, 黒田照夫
- Organizer
  第44回腸炎ビブリオシンポジウム
- Place of Presentation
  秋田
- Data Source
  KAKENHI-PROJECT-22590064
[Presentation] ブドウ球菌のバイオフィルム形成に対するAbietic acidと関連物質の影響2010
- Author(s)
  新谷真代、森江未希、野依久美子、黒田照夫、小川和加野、塩田澄子、土屋友房
- Organizer
  第55回日本ブドウ球菌研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590064
[Presentation] 腸炎ビブリオのNa+耐性に対するNa+/H+アンチポーターと呼吸鎖Na+ポンプの重要性2010
- Author(s)
  柳樂優, 谷聖人, 宮澤誠, 小川和加野, 土屋友房, 黒田照夫
- Organizer
  第22回微生物シンポジウム
- Place of Presentation
  愛媛県松山市
- Data Source
  KAKENHI-PROJECT-22590064
[Presentation] 肺炎桿菌の多剤排出ポンプと多剤耐性化2010
- Author(s)
  小川和加野、大西元康、Ni RuiTing、水澤実名子、岸野孝則、高桂鳳、黒田照夫、土屋友房
- Organizer
  第32回生体膜と薬物の総合作用シンポジウム
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-22590064
[Presentation] 肺炎桿菌の多剤排出ポンプと多剤耐性化2009
- Author(s)
  小川和加野、大西元康、Ni RuiTing、水澤実名子、岸野孝則、高桂鳳、黒田照夫、土屋友房
- Organizer
  第32回生体膜と薬物の総合作用シンポジウム
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-22590064

1. KURODA Teruo (80304327)

# of Collaborated Projects: 7 results

# of Collaborated Products: 30 results
2. TSUDA Masaaki (80132736)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
3. SHIMAMOTO Tadashi (90187443)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
4. 向畑恭男 (10028110)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. 今栄康雄 (70022712)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. 山中健生 (40028113)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. 吉田賢右 (90049073)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
8. WILSON Thomas H.

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
9. MASUDA Kazuhumi (00243486)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. MIO Mitsunobu (70190600)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. KURODA Masayuki (00253005)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. MIZUSHIMA Tohru (00264060)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. 月原冨武 (00032277)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. 徳田元 (40125943)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. OGAWA Wakano (90397878)

# of Collaborated Projects: 1 results

# of Collaborated Products: 32 results
16. OKADA Yasunobu (10025661)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. MARUMO Fumiaki (00050443)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. UEDA Kazumitsu (10151789)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. IMAI Masashi (40049010)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. TAKEGUCHI Noriaki (00019126)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. NEGISHI Kazuo (70116490)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. KOBAYASHI Sakae (90212654)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. ONO Katsuhiko (30152523)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. KAWAMURA Koki (40048286)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 前島正義 (80181577)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 山口明人 (60114336)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 野間昭典 (00132738)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 清野進 (80236067)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 笠原道弘 (40010102)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 乾賢一 (70034030)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 北里宏 (20079700)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 富田由妃 (10243487)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. MALONEY Peter C

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. KONINGS Wil, N

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. THOMAS H.Wil

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. PETER C. Mal

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. KONINGS Wil

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

TSUCHIYA Tomofusa 土屋 友房

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Analysis of multidrug resistance systems in multidrug resistant bacteria and development of drugs effective on the resistant bacteriaPrincipal Investigator

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Systematic analysis of multidrug efflux pumps in multidrug resistant bacteria and development of pump inhibitorPrincipal Investigator

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ガン化に伴うDNA複製開始制御の変化と、その抗がん剤の新規ターゲットとしての応用Principal Investigator

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Tne initiator of chromosomal DNA replication in E. coli.Principal Investigator

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Unity and diversity in active transport in cell membransPrincipal Investigator

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Structure and function of drug- and ion-extrusion systems in bacteriaPrincipal Investigator

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イオン駆動型トランスポーターとチャネルの構造・機能協関Principal Investigator

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Characteristics of ion tranport systems in Vibrio parahaemolyticus and Staphylococcus aureusPrincipal Investigator

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Molecular mechanism of energy coupling in active transportPrincipal Investigator

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Na^+/H^+アンチポーターとNa^+/H^+/基質シンポーターの共役系の解析Principal Investigator

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Structure and mechanism in cation-coupled transport systemsPrincipal Investigator

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Analysis of factors involved in serine-sensitivity in bacterial cellsPrincipal Investigator

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TSUCHIYA Tomofusa 土屋友房