Tokuda Hajime 徳田元

… Alternative Names

Researcher Number	40125943
Other IDs
External Links
Affiliation (Current)	2019: 盛岡大学, その他部局等, 名誉教授
Affiliation (based on the past Project Information) *help	2019: 盛岡大学, その他部局等, 名誉教授 2018: 盛岡大学, その他部局等, 学長 2016: 盛岡大学, 栄養科学部, 教授 2014: 盛岡大学, 栄養科学部, 教授 2012 – 2014: 盛岡大学, 栄養学部, 教授 … More
Review Section/Research Field	Principal Investigator Structural biochemistry / Biological Sciences / Applied microbiology / 代謝生物化学 / Functional biochemistry / 発酵・醸造 / Basic Section 38020:Applied microbiology-related Except Principal Investigator Biological Sciences / 機械工作 / Functional biochemistry … More
Keywords	Principal Investigator SecA / 大腸菌 / SecG / リポ蛋白質 / ABCトランスポーター / 膜局在化 / 蛋白質膜透過 / SecE / 分子シャペロン / SecY … More Except Principal Investigator 大腸菌 / 蛋白質の膜透過 / SecA / 蛋白質の分泌 / SecY / リポ蛋白質 / H^+ATPアーゼ / SecE / SecG / 腸炎ビブリオ / MPIase / タンパク質膜挿入 / 膜タンパク質 / 糖脂質酵素 / Sec蛋白質 / スルホロブス / Ydr / 膜蛋白質 / 鉄酸化細菌 / FtsH / タンパク質の膜透過 / ベン毛モーター / 細胞表層 / タンパク質輸送 / タンパク質膜透過 / タンパク質間挿入 / 細菌細胞表層 / 膜透過 / タンパク質の分泌 / 必須遺伝子 / X線結晶構造解析 / バクテリオロドプシン / リン脂質生合成 / シャペロニン / Na^+排出型呼吸鎖 / stress protein, / 構造生物学 / 外膜 / 細菌 / heat-shock protein, / シグナル配列 / トポロジー / SecD / SecF / 網羅的解析 / 分子シャペロン / 変異解析 / cytochrome P450 / 蛋白質 / チトクロムc-552 / 蛋白質の選別輸送 / ハロバクタリア / タンパク質膜挿入糖 / アーキロドプシン / stress, / SecYEG / GroEL / 局在化 / オルガネラ / 欠失変異株 / topolgy / 小胞輸送 / ハロバクテリア / ストレス蛋白質 / 熱ショックタンパク質 / プリオン / 糖脂質酵素MPIase / 可溶化剤 / 再構成 / インクルージョンボディ / endoplasmic reticulum / ストレス / 薬物代謝 / 小胞体 / 蛋白質分泌 / タンパク質 / Molecular chaperone, / フォールディング / chaperonin, / ABCトランスポーター / クローニング / 脂質修飾 / Hsp90 / タンパク質立体構造 / CdsA / シトクロムP450 / シグナルペプチド / トランスポーター / protein secretion, / YidC / signal sequence / 熱ショック蛋白質 / 膜輸送 / folding, / プロトン駆動力 / purion / 膜タンパク質可溶化剤 / ソーティング / 総括班 Less

膜外コンポーネントと共役して機能する新奇ABC輸送体の構造機能解析Ongoing
- Principal Investigator
  
  村上聡
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  Tokyo Institute of Technology
Molecular mechanisms underlying the selective membrane localization of bacterial lipoproteinsPrincipal InvestigatorOngoing
- Principal Investigator
  
  徳田元
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38020:Applied microbiology-related
- Research Institution
  Morioka College
Development of solubilizer dedicated for membrane proteins using glycolopozyme MPIase
- Principal Investigator
  
  NISHIYAMA Ken-ichi
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied biochemistry
- Research Institution
  Iwate University
Structure and function of glycolipozyme MPIase, involved in protein translocation across and integration into membranes
- Principal Investigator
  
  NISHIYAMA Ken-ichi
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Iwate University
Molecular mechanisms underlying the sorting of bacterial lipoproteins.Principal Investigator
- Principal Investigator
  
  TOKUDA Hajime
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied microbiology
- Research Institution
  Morioka College
Mechanism of substrate recognition by bacterial lipoprotein transport equipment
- Principal Investigator
  
  NARITA Shin-ichiro
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied microbiology
- Research Institution
  Kyoto University
  The University of Tokyo
Biogenesis of Escherichia coli cell envlope.Principal Investigator
- Principal Investigator
  
  TOKUDA Hajime
- Project Period (FY)
  2007 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Morioka College
  The University of Tokyo
Molecular mechanisms underlying the membrane sorting of bacterial lipoproteinsPrincipal Investigator
- Principal Investigator
  
  TOKUDA Hajime
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied microbiology
- Research Institution
  The University of Tokyo
Sorting and membrane localization of E.coli lipoproteinsPrincipal Investigator
- Principal Investigator
  
  TOKUDA Hajime
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Applied microbiology
- Research Institution
  University of Tokyo
Molecular Mechanisms underlying membrane localization and qualify control of lipoproteins in Escherichia coli cell surfacePrincipal Investigator
- Principal Investigator
  
  TOKUDA Hajime, 松山伸一
- Project Period (FY)
  2002 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
細菌リポ蛋白質の膜遊離を触媒する新規ABCトランスポーターの構造Principal Investigator
- Principal Investigator
  
  徳田元
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
大腸菌細胞表層におけるリポ蛋白質ネットワークの解明
- Principal Investigator
  
  松山伸一
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
大腸菌の全リポ蛋白質遺伝子の網羅的機能解析
- Principal Investigator
  
  松山伸一
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Development of the Expression System for Cytochrome P450 Based on the Folding Processes of Membrane Proteins
- Principal Investigator
  
  SAKAGUCHI Masao
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Functional biochemistry
- Research Institution
  KYUSHU UNIVERSITY
分泌蛋白質特異的Secチャネル複合体の構造・機能Principal Investigator
- Principal Investigator
  
  徳田元
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
Dynamic interaction between chaperone and its substrates
- Principal Investigator
  
  YOSHIDA Masasuke
- Project Period (FY)
  1997 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  KYOTO UNIVERSITY
Structure and function of protein translocation and localization systemPrincipal Investigator
- Principal Investigator
  
  TOKUDA Hajime
- Project Period (FY)
  1997 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  Structural biochemistry
- Research Institution
  University of Tokyo
分泌蛋白質特異的Secチャネルの構造と機能Principal Investigator
- Principal Investigator
  
  徳田元
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
Protein translocation across the cytoplasmic membrane of bacteriaPrincipal Investigator
- Principal Investigator
  
  TOKUDA Hajime
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Structural biochemistry
- Research Institution
  University of Tokyo
Structure and function of Sec factors involving protein translocationPrincipal Investigator
- Principal Investigator
  
  TOKUDA Hajime
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  University of Tokyo
大腸菌蛋白質膜透過系のキ-エンザイムSecAの構造と機能Principal Investigator
- Principal Investigator
  
  徳田元
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
Factors affecting the efficiency of protein secretion in E.coli.Principal Investigator
- Principal Investigator
  
  TOKUDA Hajime
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Institute of Molecular and Cellular Biosciences, University of Tokyo
大腸菌蛋白質膜透過系のキーエンザイムSecAの構造と機能Principal Investigator
- Principal Investigator
  
  徳田元
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
Reconstitution of the E.coli protein translocation machineryPrincipal Investigator
- Principal Investigator
  
  TOKUDA Hajime
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  University of Tokyo, Institute of Molecular and Cellular Biosciences
大腸菌蛋白質分泌の分子機構
- Principal Investigator
  
  水島昭二
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo University of Pharmacy and Life Science
  The University of Tokyo
再構成系による大腸菌蛋白質膜透過系の分子機構の解析Principal Investigator
- Principal Investigator
  
  徳田元
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  代謝生物化学
- Research Institution
  The University of Tokyo
精製標品を用いた再構成系による大腸菌蛋白質膜透過の分子機構Principal Investigator
- Principal Investigator
  
  徳田元
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  代謝生物化学
- Research Institution
  The University of Tokyo
蛋白質の膜透過と選別輸送の分子機構
- Principal Investigator
  
  多賀谷光男, 水島昭二
- Project Period (FY)
  1991 – 1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo University of Pharmacy and Life Science
  The University of Tokyo
原核細胞における蛋白質分泌の分子機構
- Principal Investigator
  
  水島昭二
- Project Period (FY)
  1991 – 1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo University of Pharmacy and Life Science
分必型タンパク質の膜透過の分子機構
- Principal Investigator
  
  水島昭二
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  機械工作
- Research Institution
  The University of Tokyo
再構成系とin vitro実験系による大腸菌蛋白質膜透過の分子機構の解析Principal Investigator
- Principal Investigator
  
  徳田元
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  代謝生物化学
- Research Institution
  The University of Tokyo
異環境生物のエネルギー
- Principal Investigator
  
  向畑恭男
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
異環境生物のエネルギー
- Principal Investigator
  
  向畑恭男
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
Properties and physiological roles of Na^+-motive respiratory chain in marine bacteria.Principal Investigator
- Principal Investigator
  
  TOKUDA Hajime
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  発酵・醸造
- Research Institution
  Chiba University

All 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2004 2003 Other

All Journal Article Presentation Book

[Book] Bacterial Membranes: Structural and Molecular Biology2014
- Author(s)
  Tokuda, H., Sander, P., Lee, B. L., Okuda, S., Grau, T., Tschumi, A., Brülle, J. K., Kurokawa, K., and Nakayama, H.
- Total Pages
  500
- Publisher
  Caiser Academic Press
- Data Source
  KAKENHI-PROJECT-22380049
[Book] Bacterial Lipoproteins ; Biogenesis, Trafficking and Function2012
- Author(s)
  Tokuda, H., 他8名
- Publisher
  Horizon Scientific Press(in press)
- Data Source
  KAKENHI-PROJECT-22380049
[Book] Bacterial Lipoproteins ; Biogenesis, Trafficking and Function2012
- Author(s)
  徳田元, 他8名
- Publisher
  Horizon Scientific Press(in press)
- Data Source
  KAKENHI-PLANNED-19058003
[Book] Biogenesis and membrane targeting of lipoproteins2010
- Author(s)
  Shin-ichiro Narita and Hajime Tokuda
- Publisher
  ASM Press
- Data Source
  KAKENHI-PROJECT-22780062
[Book] Sorting of bacterial lipoproteins to the outer membrane by the Lol system. In “Methods in Molecular Biology; Protein Secretion”, A. Economou (ed), DOI:10.1007/978-1-60327-412-8_7,2010
- Author(s)
  Narita, S., and Tokuda, H.
- Publisher
  Humana press
- Data Source
  KAKENHI-PLANNED-19058003
[Book] Methods in Molecular Biology ; Protein Secretion2010
- Author(s)
  Narita, S., Tokuda, H.
- Publisher
  Sorting of bacterial lipoproteins to the outer membrane by the Lol system
- Data Source
  KAKENHI-PROJECT-22380049
[Book] Sorting of bacterial lipoproteins to the outer membrane by the Lol system2010
- Author(s)
  Shin-ichiro Narita and Hajime Tokuda
- Publisher
  Humana Press
- Data Source
  KAKENHI-PROJECT-22780062
[Book] Sorting of bacterial lipoproteins to the outer membrane by the Lolsystem. In "Methods in Molecular Biology ; Protein Secretion"(A. Economou (ed))2010
- Author(s)
  Narita, S., Tokuda, H.
- Publisher
  Humana press
- Data Source
  KAKENHI-PROJECT-19380046
[Book] The function of the ABC transporter LolCDE in protein transport to the outer membrane of E. coli. In The Enzymes, vol. 25, DOI:10.1016/S1874-6047(07)25007-32007
- Author(s)
  Narita, S., and Tokuda, H.
- Data Source
  KAKENHI-PLANNED-19058003
[Book] The Periplasm2007
- Author(s)
  Tokuda, H.
- Total Pages
  415
- Publisher
  ASM press
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14037212
[Book] The function of the ABC transporter LolCDE in protein transport to the outer membrane of E. coli.2007
- Author(s)
  Narita, S., Tokuda, H.
- Publisher
  The Enzymes
- Data Source
  KAKENHI-PROJECT-19380046
[Book] ,Structure, function and transport of lipoproteins in Escherichia coli. In “The Periplasm”, M. Ehrmann (ed)2007
- Author(s)
  Tokuda, H., Matsuyama, S., and Tanaka-Masuda, K.
- Publisher
  ASM press
- Data Source
  KAKENHI-PLANNED-19058003
[Book] Structure, function and transport of lipoproteins in Escherichia coli. In "The Periplasm"(M. Ehrmann (ed))2007
- Author(s)
  Tokuda, H., Matsuyama, S., Tanaka-Masuda, K.
- Publisher
  ASM press
- Data Source
  KAKENHI-PROJECT-19380046
[Book] Bacterial lipoproteins; biogenesis, trafficking and function. In press Chapter 4 in Bacterial Membranes: Structural and Molecular Biology Han Remaut and Remi Fronzes, eds,
- Author(s)
  Tokuda, H., Sander, P., Lee, B. L., Okuda, S., Grau, T., Tschumi, A., Brulle, J. K., Kurokawa, K., and Nakayama, H.
- Publisher
  Horizon Scientific Press
- Data Source
  KAKENHI-PLANNED-19058003
[Book] Biogenesis and membrane targeting of lipoproteins. Chapter 4.3.7. In “Escherichia coli and Salmonella: cellular and molecular biology.” Bock, R. Curtiss III, J. B. Kaper, P. D. Karp, F. C. Neidhardt, T. Nystrom, J. M. Slauch, and C. L. Squires, and D. Ussery (ed), doi:10.1128/ecosal.4.3.7 (online journal).
- Author(s)
  Narita, S., and Tokuda, H.
- Publisher
  ASM Press. Washington, DC.
- Data Source
  KAKENHI-PLANNED-19058003
[Book] Biogenesis and membrane targeting of lipoproteins. In "E. coli and Salmonella"(Tracy Palmer (ed))
- Author(s)
  Narita, S., Tokuda, H.
- Publisher
  ASM Press
- Data Source
  KAKENHI-PROJECT-19380046
[Journal Article] Novel translocation intermediate allows re-evaluation of roles of ATP, proton motive force and SecG at the late stage of preprotein translocation2016
- Author(s)
  Nishiyama, K. and Tokuda, H.
- Journal Title
  
  Gene Cells
  
  Volume: ２１ Pages: 1353-1364
- DOI
  10.1111/gtc.12447
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-16H01374, KAKENHI-PROJECT-25291009, KAKENHI-PROJECT-15KT0073, KAKENHI-PROJECT-16K15083
[Journal Article] Small molecule inhibitors of Gram-negative lipoprotein trafficking discovered by phenotypic screening2015
- Author(s)
  McLeod, S. M., Fleming, P. R., MacCormack, K., McLaughlin, R. E., Whiteaker, J. D., Narita, S., Mori, M., Tokuda, H., and Miller, A. A.
- Journal Title
  
  J. Bacteriol.
  
  Volume: 197 Pages: 1075-1082
- DOI
  10.1128/jb.02352-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380049, KAKENHI-PROJECT-24570152
[Journal Article] Brown, D. G., and McLeod, S. M. Novel antibacterial targets and compounds revealed by a high throughput cell wall reporter assay.2015
- Author(s)
  Nayar, A. S., Dougherty, T. J., Ferguson, K. E., Granger, B. A., McWilliams, L., Stacey, C., Leach, L. J., Narita, S., Tokuda, H., Miller, A. A.
- Journal Title
  
  J. Bacteriol.
  
  Volume: 197
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380049
[Journal Article] Roles of the protruding loop of factor B essential for the localization of lipoproteins (LolB) in the anchoring of bacterial triacylated proteins to the outer membrane.2014
- Author(s)
  Hayashi, Y., Tsurumizu, R., Tsukahara, J., Takeda, K., Narita, S., Mori, M., Miki, K., and Tokuda, H.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 289 Pages: 10530-10539
- DOI
  10.1074/jbc.m113.539270
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380049, KAKENHI-PROJECT-24570152
[Journal Article] Glycolipozyme MPIase is essential for topology inversion of SecG during preprotein translocation2013
- Author(s)
  Moser, M., Nagamori, S., Huber, M., Tokuda, H., and Nishiyama, K.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 110 Pages: 9734-9739
- DOI
  10.1073/pnas.1303160110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380049, KAKENHI-PUBLICLY-24102503, KAKENHI-PROJECT-24591198, KAKENHI-PROJECT-25291009, KAKENHI-PROJECT-25660073, KAKENHI-PROJECT-21570110
[Journal Article] Functional differentiation of structurally similar membrane subunits of the ABC transporter LolCDE complex.2013
- Author(s)
  Mizutani, M., Mukaiyama, K., Xiao, J., Mori, M., Satou, R., Narita, S., Okuda, S., and Tokuda, H.
- Journal Title
  
  FEBS Letters
  
  Volume: 587 Pages: 23-29
- DOI
  10.1016/j.febslet.2012.11.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380049, KAKENHI-PROJECT-24570152
[Journal Article] Multiple SecA molecules drive protein translocation across a single translocon with SecG inversion2012
- Author(s)
  森田和宏、徳田元、西山賢一
- Journal Title
  
  J.Blol.Chem.
  
  Volume: 287 Pages: 455-464
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058003
[Journal Article] Defective lipoprotein sorting induces lolA expression through the Rcs stress response phosphorelay system2012
- Author(s)
  Tao, K., Narita, S., and Tokuda, H.
- Journal Title
  
  Journal of Bacteriology
  
  Volume: (in press) Pages: 3643-3650
- DOI
  10.1128/jb.00553-12
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058003, KAKENHI-PROJECT-22380049, KAKENHI-PROJECT-24570152
[Journal Article] MPIase is a glycolipozyme essential for membrane protein integration.2012
- Author(s)
  Nishiyama, K., Maeda,M., Yanagisawa,K., Nagase, R., Komura, H., Iwashita, T., Yamagaki, T., Kusumoto, S., Tokuda, H., Shimamoto, K.
- Journal Title
  
  Nat Commun
  
  Volume: 3 Pages: 1-10
- DOI
  10.1038/ncomms2267
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570110, KAKENHI-PROJECT-22310142, KAKENHI-PROJECT-22380049, KAKENHI-PUBLICLY-24102503
[Journal Article] Multiple SecA molecules drive protein translocation across a single translocon with SecG inversion.2012
- Author(s)
  Morita, K., Tokuda, H., and Nishiyama, K.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 287 Pages: 455-464
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058003
[Journal Article] Multiple SecA molecules drive protein translocation across a single translocon with SecG inversion.2012
- Author(s)
  Morita, K., Tokuda, H. and Nishiyama, K.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 287巻 Pages: 455-464
- DOI
  10.1074/jbc.m111.301754
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570110, KAKENHI-PROJECT-22380049
[Journal Article] Overexpression of LolCDE allows deletion of the Escherichia coli gene encoding apolipoprotein N-acyltransferase2011
- Author(s)
  Narita, S., Tokuda, H.
- Journal Title
  
  J.Bacteriol.
  
  Volume: 193 Pages: 4832-4840
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380049
[Journal Article] Overexpression of LolCDE allows deletion of the Escherichia coligene encoding apolipoprotein N-acyltransferase2011
- Author(s)
  成田新一郎、徳田元
- Journal Title
  
  J.Bacteriol.
  
  Volume: 193 Pages: 4832-4840
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058003
[Journal Article] Lipoprotein Sorting in Bacteria.2011
- Author(s)
  Okuda, S., and Tokuda, H.
- Journal Title
  
  Annu. Rev. Microbiol.
  
  Volume: 65 Pages: 239-259
- DOI
  10.1146/annurev-micro-090110-102859
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058003
[Journal Article] Over expression of LolCDE allows the deletion of the Escherichia coli gene encoding apolipoprotein N-acyltransferase2011
- Author(s)
  Shin-ichiro Narita and Hajime Tokuda
- Journal Title
  
  J. Bacteriol
  
  Volume: 193 Pages: 4832-4830
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22780062
[Journal Article] Lipoprotein Sorting in Bacteria2011
- Author(s)
  Okuda, S., Tokuda, H.
- Journal Title
  
  Annu.Rev.Microbiol.
  
  Volume: 65 Pages: 239-259
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380049
[Journal Article] Overexpression of LolCDE Allows Deletion of the Escherichia coli Overexpression of LolCDE alows deletion of the Eschericha coli gene2011
- Author(s)
  Narita, S., and Tokuda, H.
- Journal Title
  
  J.Bacteriol.
  
  Volume: 193 Pages: 4832-4840
- DOI
  10.1128/jb.05013-11
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058003, KAKENHI-PROJECT-22780062
[Journal Article] Application of an inducible system to engineer unmarked conditional mutants of essential genes of Pseudomonas aeruginosa.2010
- Author(s)
  Morita, Y., Narita, S., Tomida, J., Tokuda, H., and Kawamura, Y.
- Journal Title
  
  J. Microbiol. Methods
  
  Volume: 82 Pages: 205-213
- DOI
  10.1016/j.mimet.2010.06.001
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058003
[Journal Article] Biogenesis and membrane targeting of lipoproteins.In "E.coli and Salmonella"2010
- Author(s)
  Narita, S., Tokuda, H.
- Journal Title
  
  In "E.coli and Salmonella" Tracy Palmer(ed), ASM Press (掲載確定)
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058003
[Journal Article] Sorting of bacterial lipoproteins to the outer membrane by the Lol system2010
- Author(s)
  Narita, S., Tokuda, H.
- Journal Title
  
  n "Methods in Molecular Biology ; Protein secretion", A.Economou(ed), Humana press (掲載確定)
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058003
[Journal Article] A periplasmic LolA derivative with a lethal disulfide bond activates the Cpx stress response system.2010
- Author(s)
  Tao, K., Watanabe, S., Narita, S., and Tokuda, H.
- Journal Title
  
  J. Bacteriol.
  
  Volume: 192 Pages: 5657-5662
- DOI
  10.1128/jb.00821-10
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058003
[Journal Article] Biogenesis and membrane targeting of lipoproteins.2010
- Author(s)
  Shin-ichiro Narita, Hajime Tokuda
- Journal Title
  
  EcoSal-Escherichia coli and Salmonella : Cellular and Molecular Biology.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22780062
[Journal Article] Biogenesis and membrane targeting of lipoproteins2010
- Author(s)
  Narita, S., Tokuda, H.
- Journal Title
  
  Escherichia coli and Salmonella ; cellular and molecular biology
  
  Volume: Chapter4.3.7(online journal)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380049
[Journal Article] Novel mutations of the LolCDE complex causing outer membrane localization of lipoproteins despite their inner membrane retention signals2010
- Author(s)
  Chihiro Sakamoto, Rika Satou, Hajime Tokuda and Shin-ichiro Narita
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 401 Pages: 586-591
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22780062
[Journal Article] Novel mutations of the LolCDE complex causing outer membrane localization of lipoproteins despite their inner membrane retention signals2010
- Author(s)
  Sakamoto, C, Satou, R., Tokuda, H., Narita, S.
- Journal Title
  
  Biochem.Biophys.Res.Commun.
  
  Volume: 401 Pages: 586-591
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380049
[Journal Article] Novel mutations of the LolCDE complex causing outer membrane localization of lipoproteins despite their inner membrane retention signals.2010
- Author(s)
  Sakamoto, C., Satou, R., Tokuda, H., and Narita, S.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 401 Pages: 586-591
- DOI
  10.1016/j.bbrc.2010.09.106
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058003
[Journal Article] Novel mutations of the LolCDE complex causing outer membrane localization of lipoproteins despite their inner membrane retention signals.2010
- Author(s)
  Chihiro Sakamoto, Rika Satou, Hajime Tokuda, Shin-ichiro Narita
- Journal Title
  
  Biochem.Biophys.Res.Commun.
  
  Volume: 401 Pages: 586-591
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22780062
[Journal Article] A novel complete reconstitution system for membrane integration of the simplest membrane protein, Biochem. Biophys2010
- Author(s)
  Nishiyama, K., Maeda, M., Abe, M., Kanamori, T., Shimamoto, K., Kusumoto, S., Ueda, T., and Tokuda, H.
- Journal Title
  
  Res. Commun
  
  Volume: 394 Pages: 733-736
- DOI
  10.1016/j.bbrc.2010.03.061
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058003, KAKENHI-PROJECT-21570110
[Journal Article] A periplasmic LolA derivative with a lethal disulfide bond activates the Cpx stress response system2010
- Author(s)
  Tao, K., Watanabe, S., Narita, S., Tokuda, H.
- Journal Title
  
  J.Bacteriol.
  
  Volume: 192 Pages: 5657-5662
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380049
[Journal Article] Application of an inducible system to engineer unmarked conditional mutants of essential genes of Pseudomonas aeruginosa2010
- Author(s)
  Yuji Morita, Shin-ichiro Narita, Junko Tomida, Hajime Tokuda and Yoshiaki Kawamura
- Journal Title
  
  J. Microbiol. Methods
  
  Volume: 82 Pages: 205-213
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22780062
[Journal Article] A periplasmic LolA derivative with a lethal disulfide bond activates the Cpx stress response system2010
- Author(s)
  Kazuyuki Tao, Shoji Watanabe, Shin-ichiro Narita and Hajime Tokuda
- Journal Title
  
  J. Bacteriol
  
  Volume: 192 Pages: 5657-5662
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22780062
[Journal Article] A periplasmic LolA derivative with a lethal disulfide bond activates the Cpx stress response system.2010
- Author(s)
  Kazuyuki Tao, Shoji Watanabe, Shin-ichiro Narita, Hajime Tokuda
- Journal Title
  
  J.Bacteriol.
  
  Volume: 192 Pages: 5657-5662
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22780062
[Journal Article] Preparation of a highly translocation-competent proOmpA/SecB complex2010
- Author(s)
  Nishiyama, K., and Tokuda, H.
- Journal Title
  
  Protein Sci
  
  Volume: 19 Pages: 2402-2408
- DOI
  10.1002/pro.520
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058003, KAKENHI-PROJECT-21570110
[Journal Article] Sorting of bacterial lipoproteins to the outer membrane by the Lol system.2010
- Author(s)
  Shin-ichiro Narita, Hajime Tokuda
- Journal Title
  
  Methods in Molecular Biology
  
  Volume: 619 Pages: 117-129
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22780062
[Journal Article] A novel complete reconstitution system for membrane integration of the simplest membrane protein2010
- Author(s)
  Nishiyama, K., Maeda, M., Abe, M., Kanamori, T., Shimamoto, K., Kusumoto, S., Ueda, T., Tokuda, H.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 394
  
  Pages: 733-736
- Data Source
  KAKENHI-PROJECT-19380046
[Journal Article] Backbone resonance assignment for the outer membrane lipoprotein receptor LolB from Escherichia coli.2009
- Author(s)
  Nakada, S., Sakakura, M., Takahashi, H., Okuda, S., Tokuda, H., and Shimada, I.
- Journal Title
  
  Biomol. NMR Assign.
  
  Volume: 284 Pages: 121-123
- DOI
  10.1074/jbc.m109.001149
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058003
[Journal Article] Biogenesis of outer membranes in Gram-negative bacteria.2009
- Author(s)
  Tokuda, H.
- Journal Title
  
  Biosci. Biotechnol. Biochem.
  
  Volume: 73 Pages: 465-473
- DOI
  10.1007/978-1-60327-412-8_7
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058003
[Journal Article] Biochemical characterization of an ABC transporter LptBFGC complex required for the outer membrane sorting of lipopolysaccharides2009
- Author(s)
  Narita, S., Tokuda, H.
- Journal Title
  
  FEBS Lett. 583
  
  Pages: 2160-2164
- Data Source
  KAKENHI-PROJECT-19380046
[Journal Article] Structural investigation of the interaction between LolA and LolB using NMR.2009
- Author(s)
  Nakada, S., Sakakura, M., Takahashi, H., Okuda, S., Tokuda, H., Shimada, I.
- Journal Title
  
  J.Biol.Chem. 284
  
  Pages: 24634-24643
- Data Source
  KAKENHI-PROJECT-19380046
[Journal Article] Membrane topology and functional importance of the periplasmic region of ABC transporter LolCDE2009
- Author(s)
  Yasuda, M., Iguchi-Yokoyama, A., Matsuyama, S., Tokuda, H., Narita, S.
- Journal Title
  
  Biosci.Biotechnol.Biochem. 73
  
  Pages: 2310-2316
- Data Source
  KAKENHI-PROJECT-19380046
[Journal Article] Biogenesis of outer membranes in Gram-negative bacteria2009
- Author(s)
  Tokuda, H.
- Journal Title
  
  Biosci.Biotechnol.Biochem. 73
  
  Pages: 465-473
- Data Source
  KAKENHI-PROJECT-19380046
[Journal Article] Development of a functional in vitro integration system for an integral membrane protein, SecG.2009
- Author(s)
  Nishiyama, K., Tokuda, H.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 390
  
  Pages: 920-924
- Data Source
  KAKENHI-PROJECT-19380046
[Journal Article] Development of a functional in vitro integration system for an integral membrane protein, SecG2009
- Author(s)
  Nishiyama, K., Tokuda, H.
- Journal Title
  
  Biochem.Biophys.Res.Commun 390
  
  Pages: 920-924
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058003
[Journal Article] Biochemical characterization of an ABC transporter LptBFGC complex required for the outer membrane sorting of lipopolysaccharides2009
- Author(s)
  Narita, S., Tokuda, H.
- Journal Title
  
  FEBS Lett 583
  
  Pages: 2160-2164
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058003
[Journal Article] Model of mouth-to-mouth transfer of bacterial lipoproteins through inner membrane LolC, periplasmic LolA, and outer membrane LolB.2009
- Author(s)
  Okuda, S., Tokuda, H.
- Journal Title
  
  Proc.Natl.Acad.Sci., USA 106
  
  Pages: 5877-5882
- Data Source
  KAKENHI-PROJECT-19380046
[Journal Article] Dissection of the LolB function; lipoprotein binding, membrane targeting, and incorporation of lipoproteins into lipid bilayers.2009
- Author(s)
  Tsukahara, J., Mukaiyama, K., Okuda, S., Narita, S., and Tokuda, H.
- Journal Title
  
  FEBS J.
  
  Volume: 276 Pages: 4496-4504
- DOI
  10.1111/j.1742-4658.2009.07156.x
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058003
[Journal Article] Model of mouth-to-mouth transfer of bacterial lipoproteins through inner membrane LolC, periplasmic LolA, and outer membrane LolB.2009
- Author(s)
  Okuda, S., and Tokuda, H.
- Journal Title
  
  Proc. Natl. Acad. Sci., USA
  
  Volume: 106 Pages: 5877-5882
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058003
[Journal Article] Biochemical characterization of an ABC transporter LptBFGC complex required for the outer membrane sorting of lipopolysaccharides.2009
- Author(s)
  Narita, S., and Tokuda, H.
- Journal Title
  
  FEBS Lett.
  
  Volume: 583 Pages: 2160-2164
- DOI
  10.1016/j.febslet.2005.10.038
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058003
[Journal Article] Real time analysis of lipoprotein transfer from LolA to LolB by means of surface plasmon resonance2009
- Author(s)
  Tsukahara, J., Narita, S., Tokuda, H.
- Journal Title
  
  FEBS Lett. 583
  
  Pages: 2987-2990
- Data Source
  KAKENHI-PROJECT-19380046
[Journal Article] Biogenesis of outer membranes in Gram-negative bacteria2009
- Author(s)
  Tokuda, H.
- Journal Title
  
  Biosci.Biotechnol.Biochem 73
  
  Pages: 465-473
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058003
[Journal Article] Real time analysis of lipoprotein transfer from LolA to LolB by means of surface plasmon resonance.2009
- Author(s)
  Tsukahara, J., Narita, S., and Tokuda, H.
- Journal Title
  
  FEBS Lett.
  
  Volume: 583 Pages: 2987-2990
- DOI
  10.1016/j.febslet.2009.08.032
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058003
[Journal Article] Dissection of the LolB function ; lipoprotein binding, membrane targeting, and incorporation of lipoproteins into lipid bilayers2009
- Author(s)
  Tsukahara, J., Mukaiyama, K., Okuda, S., Narita, S., Tokuda, H.
- Journal Title
  
  FEBS J. 276
  
  Pages: 4496-4504
- Data Source
  KAKENHI-PROJECT-19380046
[Journal Article] Model of mouth-to-mouth transfer of bacterial lipoproteins through inner membrane LolC, periplasmic LolA, and outer membrane LolB.2009
- Author(s)
  Okuda, S., Tokuda, H.
- Journal Title
  
  Proc. Natl. Acad. Sci., USA 106
  
  Pages: 5877-5882
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058003
[Journal Article] Development of a functional in vitro integration system for an integral membrane protein, SecG, Biochem.Biophys2009
- Author(s)
  Nishiyama, K., and Tokuda, H.
- Journal Title
  
  Res. Commun
  
  Volume: 390 Pages: 920-924
- DOI
  10.1016/j.bbrc.2009.10.078
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058003, KAKENHI-PROJECT-21570110
[Journal Article] Molecular events involved in a single cycle of ligand transfer from an ATP-binding cassette transporter, LolCDE, to a molecular chaperone, LolA.2008
- Author(s)
  Taniguchi, N., Tokuda, H.
- Journal Title
  
  J. Biol. Chem. 283
  
  Pages: 8538-8544
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058003
[Journal Article] Opening and closing of the hydrophobic cavity of LolA coupled to lipoprotein binding and release.2008
- Author(s)
  Oguchi, Y., Takeda, K., Watanabe, S., Yokota, N., Miki, K., and Tokuda, H.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 283 Pages: 25414-25420
- DOI
  10.1074/jbc.m804736200
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058003
[Journal Article] A short helix in the C-terminal region of LolA is important for the specific membrane localization of lipoproteins.2008
- Author(s)
  Okuda, S., Watanabe, S., and Tokuda, H.
- Journal Title
  
  FEBS Lett.
  
  Volume: 582 Pages: 2247-2251
- DOI
  10.1016/j.febslet.2008.05.022
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058003
[Journal Article] Diacylglycerol specifically blocks spontaneous integration of membrane proteins and allows detection of a factor-assisted integration2008
- Author(s)
  Kawashima, Y., Miyazaki, E., Muller, M., Tokuda, H., Nishiyama, K.
- Journal Title
  
  J.Biol.Chem. 283
  
  Pages: 24489-24496
- Data Source
  KAKENHI-PROJECT-19380046
[Journal Article] Introduction of a lethal redox switch that controls the opening and closing of the hydrophobic cavity in LolA.2008
- Author(s)
  Watanabe, S., Oguchi, Y., Takeda, K., Miki, K., Tokuda, H.
- Journal Title
  
  J. Biol. Chem. 283
  
  Pages: 25421-25427
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058003
[Journal Article] Opening and closing of the hydrophobic cavity of LolA coupled to lipoprotein binding and release.2008
- Author(s)
  Oguchi, Y., Takeda, K., Watanabe, S., Yokota, N., Miki, K., Tokuda, H.
- Journal Title
  
  J. Biol. Chem. 283
  
  Pages: 25414-25420
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058003
[Journal Article] Opening and closing of the hydrophobic cavity of LolA coupled to lipoprotein binding and release2008
- Author(s)
  Oguchi, Y., Takeda, K., Watanabe, S., Yokota, N., Miki, K., Tokuda, H.
- Journal Title
  
  J.Biol.Chem. 283
  
  Pages: 25414-25420
- Data Source
  KAKENHI-PROJECT-19380046
[Journal Article] Molecular events involved in a single cycle of ligand transfer from an ATP-binding cassette transporter, LolCDE, to a molecular chaperone, LolA.2008
- Author(s)
  Taniguchi, N., Tokuda, H.
- Journal Title
  
  J.Biol.Chem. 283
  
  Pages: 8538-8544
- Data Source
  KAKENHI-PROJECT-19380046
[Journal Article] Diacylglycerol specifically blocks spontaneous integration of membrane proteins and allows detection of a factor-assisted integration.2008
- Author(s)
  Kawashima, Y., Miyazaki, E., Muller, M., Tokuda, H., and Nishiyama, K.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 283 Pages: 24489-24496
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058003
[Journal Article] A short helix in the C-terminal region of LolA is important for the specific membrane localization of lipoproteins2008
- Author(s)
  Okuda, S., Watanabe, S., Tokuda, H.
- Journal Title
  
  FEBS Lett. 582
  
  Pages: 2247-2251
- Data Source
  KAKENHI-PROJECT-19380046
[Journal Article] Introduction of a lethal redox switch that controls the opening and closing of the hydrophobic cavity in LolA.2008
- Author(s)
  Watanabe, S., Oguchi, Y., Takeda, K., Miki, K., and Tokuda, H.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 283 Pages: 25421-25427
- DOI
  10.1074/jbc.m804737200
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058003
[Journal Article] Introduction of a lethal redox switch that controls the opening and closing of the hydrophobic cavity in LolA.2008
- Author(s)
  Watanabe, S., Oguchi, Y., Takeda, K., Miki, K., Tokuda, H.
- Journal Title
  
  J.Biol.Chem. 283
  
  Pages: 25421-25427
- Data Source
  KAKENHI-PROJECT-19380046
[Journal Article] Diacylglycerol specifically blocks spontaneous integration of membrane proteins and allows detection of a factor-assisted integration.2008
- Author(s)
  Kawashima, Y., Miyazaki, E., Muller, M., Tokuda, H., Nishiyama, K.
- Journal Title
  
  J. Biol. Chem. 283
  
  Pages: 24489-24496
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058003
[Journal Article] Molecular events involved in a single cycle of ligand transfer from an ATP-binding cassette transporter, LolCDE, to a molecular chaperone, LolA.2008
- Author(s)
  Taniguchi, N., and Tokuda, H.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 283 Pages: 8538-8544
- DOI
  10.1074/jbc.m800026200
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058003
[Journal Article] Structure, function and transport of lipoproteins in Escherichia coli.2007
- Author(s)
  Tokuda, H.
- Journal Title
  
  The Periplasm, M. Ehrmann(ed), ASM press
  
  Pages: 67-79
- Data Source
  KAKENHI-PROJECT-14037212
[Journal Article] Structural studies of the Cpx pathway activator NlpE on the outer membrane of Escherichia coli.2007
- Author(s)
  Hirano, Y., Hossain, Md. M., Takeda, K., Tokuda, H., and Miki, K.
- Journal Title
  
  Structure
  
  Volume: 15 Pages: 963-976
- DOI
  10.1016/j.str.2007.06.014
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058003
[Journal Article] A new screening method to identify inhibitors of Lol (localization of lipoproteins) system, a novel antibacterial target2007
- Author(s)
  Ito, H., Ura, A., Oyamada, Y., Yoshida, H., Yamagishi, J., Narita, S., Matsuyama, S., Tokuda, H.
- Journal Title
  
  Microbiol.Immunol. 51
  
  Pages: 263-270
- Data Source
  KAKENHI-PROJECT-19380046
[Journal Article] Characterization of the Pseudomonas aeruginosa Lol system as a lipoprotein sorting mechanism2007
- Author(s)
  Tanaka, S., Narita, S., Tokuda, H.
- Journal Title
  
  J.Biol.Chem. 282
  
  Pages: 13379-13384
- Data Source
  KAKENHI-PROJECT-19380046
[Journal Article] Topology inversion of SecG is essential for the cytosolic SecA-dependent stimulation of protein translocation.2007
- Author(s)
  Sugai, R., Takemae, K., Tokuda, H., and Nishiyama, K.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 282 Pages: 29540-29548
- DOI
  10.1074/jbc.m704716200
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058003
[Journal Article] The Periplasm: Structure, function, and transport of lipoproteins in Escherichia coli.2007
- Author(s)
  Tokuda, H.
- Journal Title
  
  ASM press
  
  Pages: 67-79
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14037212
[Journal Article] A new screening method to identify inhibitors of Lol (localization of lipoproteins) system, a novel antibacterial target.2007
- Author(s)
  Ito, H., Ura, A., Oyamada, Y., Yoshida, H., Yamagishi, J., Narita, S., Matsuyama, S., and Tokuda, H.
- Journal Title
  
  Microbiol. Immunol.
  
  Volume: 51 Pages: 263-270
- URL
  http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1348-0421
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058003
[Journal Article] Amino acids at positions 3 and 4 determine the membrane specificity of Pseudomonas aeruginsoa lipoproteins2007
- Author(s)
  Narita, S., Tokuda, H.
- Journal Title
  
  J.Biol.Chem. 282
  
  Pages: 13372-13378
- Data Source
  KAKENHI-PROJECT-19380046
[Journal Article] Amino acids at positions 3 and 4 determine the membrane specificity of Pseudomonas aeruginsoa lipoproteins.2007
- Author(s)
  Narita, S., and Tokuda, H.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 282 Pages: 13372-13378
- DOI
  10.1074/jbc.m611839200
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058003
[Journal Article] Diverse effects of phospholipids on lipoprotein sorting and ATP hydrolysis by the ABC transporter LolCDE complex.2007
- Author(s)
  Miyamoto, S., and Tokuda, H.
- Journal Title
  
  Biochim. Biophys. Acta-Biomembranes
  
  Volume: 1768 Pages: 1848-1854
- DOI
  10.1016/j.bbamem.2007.04.005
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058003
[Journal Article] Large-scale preparation of the homogeneous LolA-lipoprotein complex and efficient in vitro transfer of lipoproteins to the outer membrane in a LolB-dependent manner.2007
- Author(s)
  Watanabe, S., Oguchi, Y., Yokota, N., and Tokuda, H.
- Journal Title
  
  Protein Sci.
  
  Volume: 16 Pages: 2741-2749
- DOI
  10.1110/ps.073101307
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058003
[Journal Article] Large-scale preparation of the homogeneous LolA-lipoprotein complex and efficient in vitro transfer of lipoproteins to the outer membrane in a LolB-dependent manner2007
- Author(s)
  Watanabe, S., Oguchi, Y., Yokota, N., Tokuda, H.
- Journal Title
  
  Protein Sci. 16
  
  Pages: 2741-2749
- Data Source
  KAKENHI-PROJECT-19380046
[Journal Article] Complete reconstitution of an ATP-binding cassette transporter LolCDE complex from separately isolated subunits.2007
- Author(s)
  Kanamaru, K., Miyamoto, S., Narita, S., and Tokuda, H.
- Journal Title
  
  FEBS J.
  
  Volume: 274 Pages: 3034-3043
- DOI
  10.1111/j.1742-4658.2007.05832.x
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058003
[Journal Article] Complete reconstitution of an ATP-binding cassette transporter LolCDE complex from separately isolated subunits2007
- Author(s)
  Kanamaru, K., Miyamoto, S., Narita, S., Tokuda, H.
- Journal Title
  
  FEBS J. 274
  
  Pages: 3034-3043
- Data Source
  KAKENHI-PROJECT-19380046
[Journal Article] Characterization of the Pseudomonas aeruginosa Lol system as a lipoprotein sorting mechanism.2007
- Author(s)
  Tanaka, S., Narita, S., and Tokuda, H.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 282 Pages: 13379-13384
- DOI
  10.1074/jbc.m611840200
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058003
[Journal Article] Diverse effects of phospholipids on lipoprotein sorting and ATP hydrolysis by the ABC transporter LolCDE complex.2007
- Author(s)
  Miyamoto, S., Tokuda, H.
- Journal Title
  
  Biochim.Biophys.Acta-Biomembranes 1768
  
  Pages: 1848-1854
- Data Source
  KAKENHI-PROJECT-19380046
[Journal Article] Structure, function and transport of lipoproteins in Escherichia coli.2006
- Author(s)
  Tokuda, H.
- Journal Title
  
  The Periplasm(M.Ehrmann(ed))(ASM press) (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15208009
[Journal Article] Structure, function and transport of lipoproteins in Escherichia coli.2006
- Author(s)
  Tokuda, H.
- Journal Title
  
  In The Periplasm, M. Ehrmann (ed), ASM press (印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15208009
[Journal Article] Structure, function and transport of lipoproteins in Escherichia coli.2006
- Author(s)
  Tokuda, H.
- Journal Title
  
  In The Periplasm(M.Ehrmann(ed))(ASM press) (印刷中)
- Data Source
  KAKENHI-PROJECT-14037212
[Journal Article] Structure, function and transport of lipoproteins in Escherichia coli.2006
- Author(s)
  Tokuda, H.
- Journal Title
  
  In The Periplasm (M.Ehrmann (ed)) (ASM press) (印刷中)
- Data Source
  KAKENHI-PROJECT-15208009
[Journal Article] 蛋白質輸送とエンベロープの形成(原核細胞)2004
- Author(s)
  徳田元
- Journal Title
  
  蛋白質核酸酵素 49
  
  Pages: 942-949
- Data Source
  KAKENHI-PROJECT-15208009
[Journal Article] 蛋白質輸送とエンベロープの形成(原核細胞)2004
- Author(s)
  徳田元
- Journal Title
  
  蛋白質・核酸・酵素 49
  
  Pages: 942-949
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15208009
[Journal Article] 蛋白質輸送とエンベロープの形成(原核細胞)2004
- Author(s)
  徳田元
- Journal Title
  
  蛋白質核酸酵素 49
  
  Pages: 942-949
- Data Source
  KAKENHI-PROJECT-14037212
[Journal Article] Protein trafficking and envelope biogenesis in bacteria.2004
- Author(s)
  Tokuda, H.
- Journal Title
  
  Protein, Nucleic acid, Enzyme 49
  
  Pages: 942-949
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15208009
[Journal Article] (Invited review) Sorting of lipoproteins to the outer membrane in E.coli.2004
- Author(s)
  Tokuda, H.
- Journal Title
  
  Biochim.Biophys.Acta. 1693
  
  Pages: 5-13
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15208009
[Journal Article] Sorting of lipoproteins to the outer membrane in E.coli.2004
- Author(s)
  Tokuda, H
- Journal Title
  
  BBA-Molecular Cell Research 1693
  
  Pages: 5-13
- Data Source
  KAKENHI-PROJECT-15208009
[Journal Article] (Invited review) Sorting of lipoproteins to the outer membrane in E.coli.2004
- Author(s)
  Tokuda, H.
- Journal Title
  
  Biophys. Acta. 1693
  
  Pages: 5-13
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15208009
[Journal Article] Sorting of lipoproteins to the outer membrane in E.coli.2004
- Author(s)
  Tokuda, H.
- Journal Title
  
  BBA-Molecular Cell Research 1693
  
  Pages: 5-13
- Data Source
  KAKENHI-PROJECT-14037212
[Presentation] タンパク質膜挿入・膜透過に関与する糖脂質酵素（Glycolipozyme）MPIaseの構造と機能2015
- Author(s)
  西山賢一、前田将秀、Moser Michael、楠本正一、徳田元、島本啓子
- Organizer
  日本農芸化学会2015年度大会　大会シンポジウム「天然物ケミカルバイオロジー研究の新展開」
- Place of Presentation
  岡山大学（岡山県岡山市）
- Year and Date
  2015-03-29
- Invited
- Data Source
  KAKENHI-PROJECT-25660073
[Presentation] タンパク質膜挿入・膜透過に関与する糖脂質酵素（Glycolipozyme）MPIaseの構造と機能2015
- Author(s)
  西山賢一、前田将秀、Moser Michael、楠本正一、徳田元、島本啓子
- Organizer
  日本農芸化学会2015年度大会　大会シンポジウム「天然物ケミカルバイオロジー研究の新展開」
- Place of Presentation
  岡山大学（岡山県岡山市）
- Year and Date
  2015-03-29
- Invited
- Data Source
  KAKENHI-PROJECT-25291009
[Presentation] 生育条件の変化に応答したLpp-ペプチドグリカントランスペプチダーゼ遺伝子の発現調節2012
- Author(s)
  青木将、福本玲、徳田元、松山伸一
- Organizer
  日本農芸化学会
- Place of Presentation
  京都女子大学
- Year and Date
  2012-03-24
- Data Source
  KAKENHI-PLANNED-19058003
[Presentation] 生育条件の変化に応答したLpp-ペプチドグリカントランスペプチダーゼ遺伝子の発現調節2012
- Author(s)
  青木将、福本玲、徳田元、松山伸一
- Organizer
  日本農芸化学会
- Place of Presentation
  京都女子大学
- Year and Date
  2012-03-24
- Data Source
  KAKENHI-PROJECT-22380049
[Presentation] How does the LolCDE complex recognize and release bacterial lipoproteins from the cytoplasmic membrane?2011
- Author(s)
  Tokuda, H.
- Organizer
  The JSPS/iCeMS International Symposium“ ABC2011 in Kyoto-ABC Proteins/Membrane Meso-domains/ES-iPS cells”
- Place of Presentation
  Kyoto University, Japan
- Data Source
  KAKENHI-PLANNED-19058003
[Presentation] Sorting of lipoproteins to the outer membrane of Gram-negative bacteria.2010
- Author(s)
  Tokuda, H.
- Organizer
  Final Keynote Address, FEBS Special Meeting “ATP-binding cassette proteins: from multidrug resistance to genetic diseases”
- Place of Presentation
  Innsbruck, Austria
- Data Source
  KAKENHI-PLANNED-19058003
[Presentation] 細菌リポタンパク質の外膜局在化を司るABCトランスポーターLolCDEの機能2010
- Author(s)
  成田新一郎、徳田元
- Organizer
  第5回トランスポーター研究会年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22780062
[Presentation] Sorting of lipoproteins to the outer membrane of Gram-negative bacteria2010
- Author(s)
  Tokuda, H.
- Organizer
  3rd FEBS Special Meetig "ATP-Binding Cassette Proteins : From Multidrug Resistance to Genetic Diseases"
- Place of Presentation
  Innsbruck(Austria)
- Year and Date
  2010-03-04
- Data Source
  KAKENHI-PROJECT-19380046
[Presentation] Sorting of lipoproteins to the outer membrane of Gram-negative bacteria2010
- Author(s)
  Tokuda, H.
- Organizer
  Final Keynote Address, FEBS Special Meeting "ATP-binding cassette proteins : from multidrug resistance to genetic diseases"
- Place of Presentation
  Innsbruck, Austria
- Data Source
  KAKENHI-PROJECT-19380046
[Presentation] Molecular events involved in a single cycle of ligand transfer from an ATP-binding cassette transporter LolCDE to a molecular chaperone LolA2008
- Author(s)
  Tokuda, H.
- Organizer
  FEBS Special Meeting "ATP-binding cassette proteins : from multidrug resistance to genetic diseases"
- Place of Presentation
  Innsbruck, Austria
- Data Source
  KAKENHI-PROJECT-19380046
[Presentation] 細菌リポタンパク質の選別と外膜局在化機構2008
- Author(s)
  徳田元
- Organizer
  第81回日本細菌学会総会
- Place of Presentation
  国立京都国際会館(京都)
- Year and Date
  2008-03-24
- Data Source
  KAKENHI-PROJECT-19380046
[Presentation] Molecular events involved in a single cycle of ligand transfer from an ATP-binding cassette transporter LolCDE to a molecular chaperone LoIA.2008
- Author(s)
  Tokuda, H.
- Organizer
  2nd FEBS Special Meeting"ATP-Binding Cassete Proteins"
- Place of Presentation
  Hotel Crauer Bar(Innsbruck,Austria)
- Year and Date
  2008-03-02
- Data Source
  KAKENHI-PROJECT-19380046
[Presentation] Molecular events involved in a single cycle of ligand transfer from an ATP-binding cassette transporter LolCDE to a molecular chaperone LolA2008
- Author(s)
  Tokuda, H.
- Organizer
  FEBS Special Meeting “ATP-binding cassette proteins: from multidrug resistance to genetic diseases”
- Place of Presentation
  Innsbruck, Austria
- Data Source
  KAKENHI-PLANNED-19058003
[Presentation] Sorting of lipoproteins to the outer membrane of Gram-negative bacteria.2007
- Author(s)
  Tokuda, H.
- Organizer
  The 2007 ASBMB meeting
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PLANNED-19058003
[Presentation] Sorting of lipoproteins to the outer membrane of gram-negative bacteria2007
- Author(s)
  Tokuda, H.
- Organizer
  ASBMB Annual Meeting
- Place of Presentation
  USA
- Year and Date
  2007-05-03
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14037212
[Presentation] Sorting of lipoproteins to the outer membrane of Gram-negative bacteria2007
- Author(s)
  Tokuda, H.
- Organizer
  The 2007 ASBMB meeting
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-19380046
[Presentation] Sorting of lipoproteins to the outer membrane of E. coli2006
- Author(s)
  Tokuda, H.
- Organizer
  ASM Conference on Protein traffic in Prokaryotes
- Place of Presentation
  Greece
- Year and Date
  2006-05-10
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14037212
[Presentation] Transport of Lipoproteins to the Outer Membranes by the LOLPathway2003
- Author(s)
  Tokuda, H.
- Organizer
  103rd American Society for Microbiology GeneralMeeting : Symposium : Protein Trafficking and Secretion
- Place of Presentation
  USA
- Year and Date
  2003-05-21
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14037212
[Presentation] Transport of Lipoproteins to the Outer Membranes by the Lol Pathway.2003
- Author(s)
  Tokuda, H.
- Organizer
  103rd American Society for Microbiology General Meeting : Symposium : Protein Trafficking and Secretion
- Place of Presentation
  USA
- Year and Date
  2003-03-21
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14037212
[Presentation] 多彩な機能を有するリポ蛋白質の膜局在化を触媒するLol経路
- Author(s)
  徳田　元
- Organizer
  日本農芸化学会
- Place of Presentation
  東北大学
- Invited
- Data Source
  KAKENHI-PROJECT-22380049
[Presentation] 大腸菌外膜リポ蛋白質輸送不全によるRcsリン酸リレー系に依存したlolA転写活性化の機構
- Author(s)
  垰和之、徳田　元
- Organizer
  日本農芸化学会
- Place of Presentation
  東北大学
- Data Source
  KAKENHI-PROJECT-22380049

1. MATSUYAMA Shin-ichi (50183108)

# of Collaborated Projects: 9 results

# of Collaborated Products: 4 results
2. NISIYAMA Kennichi (80291334)

# of Collaborated Projects: 4 results

# of Collaborated Products: 15 results
3. NARITA Shin-ichiro (30338751)

# of Collaborated Projects: 4 results

# of Collaborated Products: 34 results
4. 水島昭二 (50013313)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
5. ITO Koreaki (90027334)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. YOSHIDA Masasuke (90049073)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. OMURA Tsuneo (80029933)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. TAO Kazuyuki (00211996)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
9. SHIMAMOTO Keiko (70235638)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
10. 多賀谷光男 (30179569)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. 向畑恭男 (10028110)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. 山中健生 (40028113)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. 土屋友房 (80012673)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. 今栄康雄 (70022712)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. 村上聡 (30300966)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
16. TAKEDA Kazuki (30332290)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
17. WATANABE Makoto (20142408)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. YAMANE Kunio (20013336)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. HIRATA Hajime (40049052)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. ENDO Toshiya (70152014)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. GOTO Yuji (40153770)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. KOHNO Kenji (50142005)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. KUWAJIMA Kunihiro (70091444)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. FUNATSU Takashi (00190124)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. SAKAGUCHI Masao (30205736)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 内田欣哉 (60013330)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 中野明彦 (90142140)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 坪井昭三 (57004554)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 吉田匡 (10004673)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 勝沼信彦 (50035375)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 山根國男 (32001336)

# of Collaborated Projects: 1 results

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32. 南康文 (40181953)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 河田康志 (40177697)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 石川統 (70012482)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. KUSANO Kazutomi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. MOSER Michael

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
37. HUBER Maria

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. SASAKI Masaru

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. SATO Ryo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. ENDO Yuta

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. SAWASATO Katsuhiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
42. NISHIKAWA Hanako

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
43. SHIMIZU Yuko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
44. NAKAMURA Shota

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
45. SAIKUDO Mari

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
46. KUSUMOTO Shoichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
47. 永森收志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tokuda Hajime 徳田 元

徳田 元 トクダ ハジメ

TOKUDA Hajime 徳田 元

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Co-Researchers

膜外コンポーネントと共役して機能する新奇ABC輸送体の構造機能解析Ongoing

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Molecular mechanisms underlying the selective membrane localization of bacterial lipoproteinsPrincipal InvestigatorOngoing

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Molecular mechanisms underlying the sorting of bacterial lipoproteins.Principal Investigator

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Biogenesis of Escherichia coli cell envlope.Principal Investigator

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Molecular mechanisms underlying the membrane sorting of bacterial lipoproteinsPrincipal Investigator

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Sorting and membrane localization of E.coli lipoproteinsPrincipal Investigator

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Molecular Mechanisms underlying membrane localization and qualify control of lipoproteins in Escherichia coli cell surfacePrincipal Investigator

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細菌リポ蛋白質の膜遊離を触媒する新規ABCトランスポーターの構造Principal Investigator

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Tokuda Hajime 徳田元

徳田元トクダハジメ

TOKUDA Hajime 徳田元