MATSUYAMA Shin-ichi 松山伸一

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MATSUYAMA Shinichi 松山伸一

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Researcher Number	50183108
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2003 – 2009: 立教大学, 理学部, 教授 2004: 立教大学, 理学部・生命理学科, 教授 2000 – 2002: 東京大学, 分子細胞生物学研究所, 助教授 1995: University of Tokyo, Institute of Molecular and Cellular Biosciences, Associate, 分子細胞生物学研究所, 助教授 1993 – 1994: 東京大学, 分子細胞生物学研究所, 助手 1989 – 1992: 東京大学, 応用微生物研究所, 助手 1990: 東京大学応用微生物研究所, 助手
Review Section/Research Field	Principal Investigator Biological Sciences / Applied microbiology / Structural biochemistry / 応用微生物学・応用生物化学 Except Principal Investigator Biological Sciences / Functional biochemistry / 代謝生物化学 / 機械工作
Keywords	Principal Investigator 大腸菌 / リポ蛋白質 / 外膜 / 細胞表層 / 局在化 / リポタンパク質 / 化学療法剤 / Escherichia coli / outer membrane / lipoprotein … More / ATP / 生合成 / 内膜 / タンパク質輸送 / 必須遺伝子 / タンパク質局在化 / chemotherapentic / localization / biosynthesis / inner membrane / cell surface / sorting signal / ABC transporter / Lol system / membrane localization / 相互作用 / ABCトフンスボーター / 選別シグナル / ABCトランスポーター / Lolシステム / 膜局在化 / トランスペプチダーゼ / スクリーニング / グラム陰性細菌 / 網羅的解析 / 脂質修飾 / クローニング / 欠失変異株 / Secタンパク質 / タンパク質膜透過 … More Except Principal Investigator 大腸菌 / SecA / リポ蛋白質 / 再構成 / タンパク質の膜透過 / タンパク質の分泌 / SecG / リポタンパク質 / 細胞表層 / 膜局在化 / 分子シャペロン / ABCトランスポーター / 外膜 / 蛋白質膜透過 / シグナルペプチド / Reconstruction / outer mambrane / mambrane localization / Escherichia coli / molecular chaperone / ABC transporter / lipoprotein / タンパク質局在化 / プロテアーゼ / ペリプラズム / 品質管理 / Everted membrane vesicles / Precursor protein / Chaperone / E.coli / Protein secretion / Overproduction of Sec factors / Sec因子大量発現 / 蛋白質分泌装置 / 分泌型蛋白質 / SecB / 酸性リン脂質 / 反転膜小胞 / 前駆体蛋白質 / シャペロン / 蛋白質分泌 / Sec因子の大量発現 / プロテアーゼ【IV】 / バイオエナジェティックス / タンパク質の膜透過のエネルギー要求性 / シグナルペプチドペプチダーゼ / シグナルペプチターゼ / SecAタンパク質 / バイオエナジエティックス / タンパク質膜透過のエネルギー要求性 / タンパク質膜透過のin vitro系 / 膜タンパク質 / ビブリオ菌 / ATP / 生合成 / βバレル型タンパク質 / 蛋白質輸送 / Secトランスロコン / Lolシステム / 外膜形成 / エンベロープストレス / リポ多糖 / Lol 因子 / βバレル型蛋白質 / 細胞質膜 / プロテオリポソーム / ATPアーゼ / 再構成系 / ATPase / ス-パ-シグナルペプチド / 人工シグナルペプチド / シグナルペプチド疎水域 / シグナルペプチド正荷電域 / スーパーシグナルペプチド / プロトン駆動力 / SecF / SecD / SecE / SecY Less

Biogenesis of Escherichia coli cell envlope.
- Principal Investigator
  
  TOKUDA Hajime
- Project Period (FY)
  2007 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Morioka College
  The University of Tokyo
Analyses on periplasmic enzymes that covalently bind lipoproteins to peptidoglycan in Escherichia coliPrincipal Investigator
- Principal Investigator
  
  MATSUYAMA Shinichi
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied microbiology
- Research Institution
  Rikkyo University
Fundamental studies on development of chemotherapeutics targeting cell surface proteins which are essential for growth in Escherichia coliPrincipal Investigator
- Principal Investigator
  
  MATSUYAMA Shin-ichi
- Project Period (FY)
  2003 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied microbiology
- Research Institution
  Rikkyo University
Molecular Mechanisms underlying membrane localization and qualify control of lipoproteins in Escherichia coli cell surfacePrincipal Investigator
- Principal Investigator
  
  TOKUDA Hajime, 松山伸一
- Project Period (FY)
  2002 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
大腸菌細胞表層におけるリポ蛋白質ネットワークの解明Principal Investigator
- Principal Investigator
  
  松山伸一
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
グラム陰性細菌のリポ蛋白質を標的とする化学療法剤の開発Principal Investigator
- Principal Investigator
  
  松山伸一
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
大腸菌の全リポ蛋白質遺伝子の網羅的機能解析Principal Investigator
- Principal Investigator
  
  松山伸一
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Functional analyzes on an ABC transporter involved in the selective release of outer membrane lipoproteins from membranesPrincipal Investigator
- Principal Investigator
  
  MATSUYAMA Shin-ichi
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  The University of Tokyo
大腸菌蛋白質膜透過系のキ-エンザイムSecAの構造と機能
- Principal Investigator
  
  徳田元
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
大腸菌外膜リポタンパク質の外膜への局在化機構Principal Investigator
- Principal Investigator
  
  松山伸一
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  The University of Tokyo
Factors affecting the efficiency of protein secretion in E.coli.
- Principal Investigator
  
  TOKUDA Hajime
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Institute of Molecular and Cellular Biosciences, University of Tokyo
大腸菌蛋白質膜透過系のキーエンザイムSecAの構造と機能
- Principal Investigator
  
  徳田元
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
膜透過したタンパク質の膜からの放出に関する研究Principal Investigator
- Principal Investigator
  
  松山伸一
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Structural biochemistry
- Research Institution
  The University of Tokyo
分必型タンパク質の膜透過の分子機構
- Principal Investigator
  
  水島昭二
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  機械工作
- Research Institution
  The University of Tokyo
スーパーシグナルペプチドの開発と有用タンパク質の分泌生産への応用
- Principal Investigator
  
  水島昭二
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  代謝生物化学
- Research Institution
  The University of Tokyo
タンパク質の膜透過・分泌の機構
- Principal Investigator
  
  水島昭二
- Project Period (FY)
  1986 – 1989
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Research Institution
  The University of Tokyo
  Nagoya University

All 2012 2009 2007 2004

All Journal Article Presentation Book

[Book] ,Structure, function and transport of lipoproteins in Escherichia coli. In “The Periplasm”, M. Ehrmann (ed)2007
- Author(s)
  Tokuda, H., Matsuyama, S., and Tanaka-Masuda, K.
- Publisher
  ASM press
- Data Source
  KAKENHI-PLANNED-19058003
[Journal Article] Membrane Topology and Functional Importance of the Periplasmic Region of ABC Transporter LolCDE.2009
- Author(s)
  Yasuda M., Matsuyama S., 他
- Journal Title
  
  Biosci.Biotechnol.Biochem 73
  
  Pages: 2310-2316
- NAID
  10027547063
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19580099
[Journal Article] Membrane Topology and Functional Importance of the Periplasmic Region of ABC Transporter LolCDE.2009
- Author(s)
  Yasuda M., Iguchi-Yokoyama A., Matsuyama S., Tokuda H., Narita S.
- Journal Title
  
  Biosci. Biotechnol. Biochem. 73
  
  Pages: 2310-2316
- NAID
  10027547063
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19580099
[Journal Article] Structural investigation of the interaction between LolA and LolB using NMR.2009
- Author(s)
  Nakada, S., Sakakura, M., Takahashi, H., Okuda, S., Tokuda, H., and Shimada, I.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 284 Issue: 36 Pages: 24634-24643
- DOI
  10.1074/jbc.m109.001149
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058003
[Journal Article] A new screening method to identify inhibitors of Lol (localization of lipoproteins) system2007
- Author(s)
  Ito, H., Ura, A., Oyamada, Y., Yoshida, H., Yamagishi, J., Narita, S., Matsuyama, S., Tokuda, H.
- Journal Title
  
  a novel antibacterial target. Microbiol. Immunol 51
  
  Pages: 263-270
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19580099
[Journal Article] Structure, function and transport of lipoproteins in Escherichia coli. In The Periplasm, M. Ehrmann (ed)2007
- Author(s)
  Tokuda, H., Matsuyama, S., Tanaka-Masuda, K.
- Journal Title
  
  ASM press
  
  Pages: 67-79
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19580099
[Journal Article] A new screening method to identify inhibitors of Lol (localization of lipoproteins) system, a novel antibacterial target.2007
- Author(s)
  Ito, H., Ura, A., Oyamada, Y., Yoshida, H., Yamagishi, J., Narita, S., Matsuyama, S., and Tokuda, H.
- Journal Title
  
  Microbiol. Immunol.
  
  Volume: 51 Pages: 263-270
- NAID
  10020280998
- URL
  http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1348-0421
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058003
[Journal Article] 外膜蛋白質の輸送2004
- Author(s)
  松山伸一
- Journal Title
  
  蛋白質・核酸・酵素 49
  
  Pages: 965-966
- Data Source
  KAKENHI-PROJECT-15380056
[Presentation] 生育条件の変化に応答したLpp-ペプチドグリカントランスペプチダーゼ遺伝子の発現調節2012
- Author(s)
  青木将、福本玲、徳田元、松山伸一
- Organizer
  日本農芸化学会
- Place of Presentation
  京都女子大学
- Year and Date
  2012-03-24
- Data Source
  KAKENHI-PLANNED-19058003

1. TOKUDA Hajime (40125943)

# of Collaborated Projects: 9 results

# of Collaborated Products: 4 results
2. 水島昭二 (50013313)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. 内田欣哉 (60013330)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. NISIYAMA Kennichi (80291334)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. NARITA Shin-ichiro (30338751)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. TAO Kazuyuki (00211996)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. TAKEDA Kazuki (30332290)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 疋田千波 (60222238)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 市原茂幸 (30092993)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 山田寿美 (30089859)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

MATSUYAMA Shin-ichi 松山 伸一

MATSUYAMA Shinichi 松山 伸一

Research Projects

Research Products

Co-Researchers

Biogenesis of Escherichia coli cell envlope.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analyses on periplasmic enzymes that covalently bind lipoproteins to peptidoglycan in Escherichia coliPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Fundamental studies on development of chemotherapeutics targeting cell surface proteins which are essential for growth in Escherichia coliPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular Mechanisms underlying membrane localization and qualify control of lipoproteins in Escherichia coli cell surfacePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

大腸菌細胞表層におけるリポ蛋白質ネットワークの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

グラム陰性細菌のリポ蛋白質を標的とする化学療法剤の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

大腸菌の全リポ蛋白質遺伝子の網羅的機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional analyzes on an ABC transporter involved in the selective release of outer membrane lipoproteins from membranesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

大腸菌蛋白質膜透過系のキ-エンザイムSecAの構造と機能

Principal Investigator

Project Period (FY)

Research Category

Research Institution

大腸菌外膜リポタンパク質の外膜への局在化機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Factors affecting the efficiency of protein secretion in E.coli.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

大腸菌蛋白質膜透過系のキーエンザイムSecAの構造と機能

Principal Investigator

Project Period (FY)

Research Category

Research Institution

膜透過したタンパク質の膜からの放出に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

MATSUYAMA Shin-ichi 松山伸一

MATSUYAMA Shinichi 松山伸一