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YOSHIDA Tadashi
吉田 匡
Connect your ORCID iD
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Researcher Number
10004673
Other IDs
External Links
Affiliation (Current)
2022: 山形大学, 医学部, その他
Affiliation (based on the past Project Information)
*help
1987 – 2007: School of Med. Dept. of Molecular and Pathological Biochemistry, Professor, 医学部, 教授
1986 – 1987: 山形大学, 医学部, 助教授
1986: 山形大, 医学部, 助教授
Review Section/Research Field
Principal Investigator
Functional biochemistry
/
Structural biochemistry
/
General medical chemistry
/
代謝生物化学
/
Functional biochemistry
Except Principal Investigator
代謝生物化学
/
Functional biochemistry
/
Pathological medical chemistry
/
General medical chemistry
/
Cell biology
/
Functional biochemistry
Keywords
Principal Investigator
CO / ヘムオキシゲナーゼ / ビリベルジン / 酸素活性化機構 / ヘムの分解 / ヘム / ビリルビン / オキシゲナーゼ / 酵素活性化機構 / Heme oxygenase
…
More
/ Hmu O / 酵素活性化 / フマラーゼ / アイソザイム / ヘム分解 / ビソルビン / Bilirubin / 細菌のヘム分解酵素 / ピリルビン / ビリベルジン還元酵素 / HEME OXYGENASE / OXYGEN ACTIVATION / BILIVERDIN / ベルドヘム / シアノバクテリア / ジフテリア菌 / Corynebacterium diphtheriae / 核 / ミトコンドリア / ペルオキシソーム / 液泡 / プラスチド / 前駆体蛋白質 / 膜透過 / 液胞 / 翻訳調節 / COS細胞での発現 / 酸素親和性 / CO親和性 / 酸素活圧化 / ビソベルジン / ヘムオキシゲナ-ゼ / 大腸菌での発現 / 部位指定変異 / 小胞体への定着機構 / ヘムポケット / heme oxygenase / Expression in E. coli / site directed mutagenesis / Insertion mechanism to microsome / heme pocket / ビリベリジン / Oxygenase / O_2 activation mechanism / Heme / Degradation of heme / Bieiverdin / HmuO / ヘムオキシグナーゼ / オキシグナーゼ / Heme degradation / Heme degradation enzyme / Activation of oxygen / biliverdin / 中間過程 / ピリペルジン / HEME DEGRADATION / INTERMEDIARY STEP / BILIVERDIN REDUCTASE / BILIRUBIN / ヒドロペルオキソ / メソヒドロキシヘム / HYDROPEROXO SPECIES / meso-HYDROXYHEME / VERDOHEME / CYANOBACTERIUM / 酸素活性化 / ヒドロキシヘム / 大豆ヘムオキシゲナーゼ / ピリベルジン / 鉄 / 過酸化水素 / ショウジョウバエ / Oxygen activation / Hydroxyheme / Verdoheme / Biliverdin / Cyanobacterium / Soybean, GmHO-1 / 蛋白質カルボキシメチル化反応 / O-メチレーション / チュブリン / 高分子単微小管結合蛋白質 / 高分子量微小管結合蛋白質 / Protein carboxymethyltransferase / O-methylation / Tubulin / フマラ-ゼ / フマラ-ゼのcDNA / フマラ-ゼの生成 / フマラーゼのcDNA / フマラーゼの生成 / Fumarase / Isozyme / cDNA for fumarase / Production of fumarase
…
More
Except Principal Investigator
ヘムオキシゲナーゼ / ミトコンドリア / カドミウム / ヘム分解酵素 / mitochondria / 蛋白質の膜透過 / 蛋白質の選別輸送 / 総括班 / 遺伝子発現調節 / メタルレスポンシブエレメント / ストレスタンパク質 / ヒートショックタンパク質 / 転写調節 / ミトコンドリア蛋白質前駆体 / 輸送装置 / コンタクトサイト / 膜透過装置 / バイパス輸送 / 細胞質因子 / bypass-import / heme oxygenase / 膜透過 / 小胞輸送 / ソーティング / オルガネラ / タンパク質輸送 / 蛋白質の分泌 / 転写制御 / ストレス / ヘム / USF / 転写因子 / 蛋白質カルボキシメチル基転移酵素 / cDNAクロ-ニング / 老化 / 脳 / 蛋白質メチル化 / Sーアデノシルメチオニン / 神経生化学 / cDNA塩基配列解析 / 異常アスパラギン酸 / 蛋白質一次構造 / Protein carboxyl methyltransferase / Aging / cDNA for protein carboxyl methyltransferase / Brain / Methylation / 延長ペプチド / 前駆体蛋白質受容体 / 前駆体蛋白質 / mitochondrial protein precursor / presequence / import machinery / contact site / translocation machinery / ヘムオキシゲナ-ゼ / ストレス関連蛋白質 / CATアッセイ / 遺伝子発現 / transcriptional control / stress protein / heat shock protein / cadmium / HSP32 / degradation of heme / 蛋白質輸送 / 再輸送 / ポリン / 膜間腔蛋白質 / protein transport / transport machinery / re-translocation / porin / 蛋白質のターゲッティング / 蛋白質膜透過 / ミトコンドリア外膜 / ミトコンドリア内膜 / プレシークエンス / protein targeting / protein translocation / mitochondrial outer membrane / mitochondrial inner membrane / 酵素反応機構 / 生物種依存性 / 分子認識 / タンパク質 / 反応制御 / enzymatic reaction mechanism / specificity of species / molecular recognition / protein / regulation of reactions / 付加ペプチド / オルニナンアミノ基転移酵素前駆体 / 前駆体受容体 / 蛋白質細胞内局在化機構 / 附加ペプチド / オルニチンアミノ基転移酵素前駆体 / リポソーム / 細胞内局在化機構 / Mitochondria / Fxtra-peptide / Precursor of Ornithine aminotransferase / Cytosolic factor / Receptor for precursor protein
Less
Research Projects
(
27
results)
Research Products
(
1
results)
Co-Researchers
(
32
People)
Project Start Year (Newest)
Project Start Year (Oldest)
How different biological species make heme oxygenase suit their own needs?_Elucidation of the dependence of heme catabolism on species
Principal Investigator
MIGITA Taiko
Project Period (FY)
2006 – 2007
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Functional biochemistry
Research Institution
Yamaguchi University
Mechanism of heme degradation by heme oxygenase and diversity of heme oxygenase among the various organisms
Principal Investigator
Principal Investigator
YOSHIDA Tadashi
Project Period (FY)
2004 – 2006
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Functional biochemistry
Research Institution
Yamagata University
Mechanism of heme degradation by heme oxygenase and the interaction of heme
Principal Investigator
Principal Investigator
YOSHIDA Tadashi
Project Period (FY)
2002 – 2003
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Functional biochemistry
Research Institution
Yamagata University
Relation between the structure and the oxygen acitivation of heme oxygenase reaction
Principal Investigator
Principal Investigator
YOSHIDA Tadashi
Project Period (FY)
2000 – 2001
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Functional biochemistry
Research Institution
YAMAGATA UNIVERSITY
ヘムオキシゲナーゼの構造と機能との関連(特に酸素活性化について)
Principal Investigator
Principal Investigator
吉田 匡
Project Period (FY)
1999
Research Category
Grant-in-Aid for Scientific Research on Priority Areas (A)
Research Institution
Yamagata University
ヘムオキシゲナーゼの構造と機能との関連(特に酸素活性化について)
Principal Investigator
Principal Investigator
吉田 匡
Project Period (FY)
1998
Research Category
Grant-in-Aid for Scientific Research on Priority Areas (A)
Research Institution
Yamagata University
Mechanism of heme degradation by heme oxygenase
Principal Investigator
Principal Investigator
YOSHIDA Tadashi
Project Period (FY)
1998 – 1999
Research Category
Grant-in-Aid for Scientific Research (A).
Research Field
Structural biochemistry
Research Institution
YAMAGATA UNIVERSITY
Molecular Mechanism of Mitochondrial Protein Import and Sorting
Principal Investigator
ONO Hideyu
Project Period (FY)
1998 – 1999
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Cell biology
Research Institution
YAMAGATA UNIVERSITY
ヘムオキシゲナーゼの構造と機能との関連(特に酸素活性化について)
Principal Investigator
Principal Investigator
吉田 匡
Project Period (FY)
1997
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Yamagata University
Molucular mechanisms of oxygen activation at the three steps in heme oxygenase reaction
Principal Investigator
Principal Investigator
YOSHIDA Tadashi
Project Period (FY)
1997 – 1998
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Functional biochemistry
Research Institution
YAMAGATA UNIVERSITY
ヘムオキシゲナーゼの構造と機能との関連(特に酸素活性化について)
Principal Investigator
Principal Investigator
吉田 匡
Project Period (FY)
1996
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Yamagata University
重金属ストレスによる群特異的遺伝子転写調節機構の解明
Principal Investigator
佐藤 道比古
Project Period (FY)
1996
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Functional biochemistry
Research Institution
Yamagata University
ヘムオキシゲナーゼによるヘム分解の中間過程の解析
Principal Investigator
Principal Investigator
吉田 匡
Project Period (FY)
1996
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Functional biochemistry
Research Institution
Yamagata University
Molecular mechanism of heme degradation catalyzed by heme oxygenase
Principal Investigator
Principal Investigator
YOSHIDA Tadashi
Project Period (FY)
1996 – 1997
Research Category
Grant-in-Aid for international Scientific Research
Research Field
Structural biochemistry
Research Institution
YAMAGATA UNIVERSITY
ラットヘムオキシゲナーゼ遺伝子の重金属による転写調節機構
Principal Investigator
SATO Michihiko
Project Period (FY)
1994
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Functional biochemistry
Research Institution
Yamagata University
一つのmRNAから翻訳される二種のフマラーゼアイソザイムの生成機構
Principal Investigator
Principal Investigator
吉田 匡
Project Period (FY)
1993
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Functional biochemistry
Research Institution
Yamagata University
核、ミトコンドリア、ペルオキシソーム蛋白質局在化の分子機構
Principal Investigator
Principal Investigator
吉田 匡
Project Period (FY)
1992 – 1994
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Yamagata University
Mechanism of targeting and transport of mitochondrial precursor proteins to mitochondria
Principal Investigator
ISHIKAWA Kazunobu
,
斧 秀勇
Project Period (FY)
1992 – 1993
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
General medical chemistry
Research Institution
Yamagata University
蛋白質の膜透過と選別輸送の分子機構
Principal Investigator
水島 昭二
Project Period (FY)
1991
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
The University of Tokyo
蛋白質の膜透過と選別輸送の分子機構
Principal Investigator
多賀谷 光男
,
水島 昭二
Project Period (FY)
1991 – 1994
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Tokyo University of Pharmacy and Life Science
The University of Tokyo
On the role of heme oxygenase as a oxygen radical scavenger
Principal Investigator
SATO Michihiko
Project Period (FY)
1991 – 1992
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Pathological medical chemistry
Research Institution
Yamagata University
Molecular mechanism of recognition of mitochondrial protein precursor by mitochondria
Principal Investigator
ONO Hideyu
,
坪井 昭三
Project Period (FY)
1990 – 1991
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
代謝生物化学
Research Institution
Yamagata University
Relation between structure and function of heme oxygenase and its insertion mechanism to microsomal membranes
Principal Investigator
Principal Investigator
YOSHIDA Tadashi
Project Period (FY)
1990 – 1991
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
代謝生物化学
Research Institution
Yamagata University
On the Protein Carboxyl Methylation of the Aged Protein in the Brain
Principal Investigator
SATO Michihiko
Project Period (FY)
1989 – 1990
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
代謝生物化学
Research Institution
Yamagata University
Mechanism of the production of two isozymes of fumarase encoded from a single gene
Principal Investigator
Principal Investigator
YOSHIDA Tadashi
Project Period (FY)
1988 – 1989
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
General medical chemistry
Research Institution
Yamagata University
Research on the receptor for the precursors of mitochondrial proteins and the cytosolic factor required for their import
Principal Investigator
TUBOI Syozo
Project Period (FY)
1986 – 1987
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
代謝生物化学
Research Institution
Yamagata University School of Medicine, Department of Biochemistry
Protein carboxymethyltransferase and its physiological significance
Principal Investigator
Principal Investigator
YOSHIDA Tadashi
Project Period (FY)
1986 – 1987
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
General medical chemistry
Research Institution
Yamagata University
All
2006
All
Journal Article
[Journal Article] Migita
2006
Author(s)
Tomohiko, Gohya, Xuhong, Zhang, Tadashi, Yoshida, Catharina, T
Journal Title
the FEBS Journal 273
Pages
: 5384-5399
Description
「研究成果報告書概要(欧文)」より
Data Source
KAKENHI-PROJECT-18570130
# of Projects (Dsc)
# of Projects (Asc)
1.
SATO Michihiko
(00135344)
# of Collaborated Projects:
11 results
# of Collaborated Products:
0 results
2.
FUJII Hiroshi
(80228957)
# of Collaborated Projects:
8 results
# of Collaborated Products:
0 results
3.
ONO Hideyu
(40160915)
# of Collaborated Projects:
7 results
# of Collaborated Products:
0 results
4.
MIGITA Taiko
(90159161)
# of Collaborated Projects:
7 results
# of Collaborated Products:
0 results
5.
ZHANG Zuhong
(10292442)
# of Collaborated Projects:
6 results
# of Collaborated Products:
0 results
6.
ISHIKAWA Kazunobu
(80222959)
# of Collaborated Projects:
5 results
# of Collaborated Products:
0 results
7.
TUBOI Syozo
(70004554)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
8.
水島 昭二
(50013313)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
9.
大村 恒雄
(80029933)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
10.
多賀谷 光男
(30179569)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
11.
IUCHI Yoshihito
(60272069)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
12.
MIGITA Kouto
(90116757)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
13.
田代 裕
(40077558)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
14.
加藤 敬太郎
(70037571)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
15.
米田 悦啓
(80191667)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
16.
橋本 隆
(80009935)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
17.
長谷 俊治
(00127276)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
18.
伊藤 明夫
(30037379)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
19.
森 正敬
(40009650)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
20.
中野 明彦
(90142140)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
21.
徳田 元
(40125943)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
22.
勝沼 信彦
(50035375)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
23.
鈴木 民夫
(30206502)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
24.
野口 正人
(10124611)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
25.
OLSON John S.
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
26.
IKEDA-SAITO Masao
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
27.
周 虹
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
28.
ZHOU Hong
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
29.
兪 善昌
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
30.
ROUSSEAU Den
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
31.
IKEDAーSAITO マサオ
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
32.
OLSOH John S
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
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