Chou Kyokukou 張旭紅

… Alternative Names

張旭紅チヨウキヨクコウ

ZHANG Xuhong 張旭紅

ZHANG Zuhong 張旭紅

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Researcher Number	10292442
Other IDs
Affiliation (Current)	2025: 山形大学, 大学院医学系研究科, 助教
Affiliation (based on the past Project Information) *help	2025: 山形大学, 大学院医学系研究科, 助教 2020 – 2023: 山形大学, 大学院医学系研究科, 助教 2014: 山形大学, 大学院医学系研究科, 助教 2013 – 2014: 山形大学, 医学(系)研究科(研究院), 助教 2012: 山形大学, 医学系研究院, 助教 1998 – 2006: YAMAGATA UNIVERSITY SCHOOL OF MEDICINE,DEPARTMENT OF BIOCHEMISTRY,INSTRUCTOR, 医学部, 助手
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 56050:Otorhinolaryngology-related Except Principal Investigator Functional biochemistry / Basic Section 53030:Respiratory medicine-related / Functional biochemistry / Structural biochemistry / Gastroenterology / Living organism molecular science
Keywords	Principal Investigator 口腔癌 / 核酸医薬 / microRNA / 核酸外用薬 / 核酸薬外用薬 / miRNA Except Principal Investigator CO / ヘムオキシゲナーゼ / ビリベルジン / ビリルビン … More / ヘムの分解 / 酸素活性化機構 / 酵素活性化 / Hmu O / 酵素活性化機構 / ヘム / Corynebacterium diphtheriae / ジフテリア菌 / シアノバクテリア / ベルドヘム / BILIVERDIN / OXYGEN ACTIVATION / HEME OXYGENASE / ビリベルジン還元酵素 / Heme oxygenase / ピリルビン / 細菌のヘム分解酵素 / オキシゲナーゼ / 非小細胞肺癌 / CTOS作製 / 長鎖非コードRNA / スフェロイド / オルガノイド / 肺癌 / lncRNA / Soybean, GmHO-1 / Cyanobacterium / Biliverdin / Verdoheme / Hydroxyheme / Oxygen activation / ショウジョウバエ / 過酸化水素 / 鉄 / ピリベルジン / 大豆ヘムオキシゲナーゼ / ヒドロキシヘム / 酸素活性化 / CYANOBACTERIUM / VERDOHEME / meso-HYDROXYHEME / HYDROPEROXO SPECIES / メソヒドロキシヘム / ヒドロペルオキソ / BILIRUBIN / BILIVERDIN REDUCTASE / INTERMEDIARY STEP / HEME DEGRADATION / ピリペルジン / 中間過程 / ヘム分解 / Bilirubin / biliverdin / Activation of oxygen / Heme degradation enzyme / Heme degradation / オキシグナーゼ / ヘムオキシグナーゼ / HmuO / 肝がん / 診断マーカー / 分子標的治療 / microRNA / 肝癌 / 環境変化 / 反応調節 / 環境応答機構 / ESI-MSによる逐次反応速度論解析 / 酸性化環境への適応 / 酸素消費の速度論解析 / 酵素活性の微調節 Less

口腔癌治療用RNA医薬のDDS最適化研究Principal Investigator
- Principal Investigator
  
  張旭紅
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Yamagata University
Development of a microRNA-based drug against oral cancerPrincipal Investigator
- Principal Investigator
  
  張旭紅
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Yamagata University
Attempt to establish a novel therapeutic approach targeting long non-coding RNAs for EGFR-TKI-resistant lung cancer
- Principal Investigator
  
  SHO Ri
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Yamagata University
A translational research on miR-224: towards novel diagnostic and therapeutic approach for hepatocellular carcinoma
- Principal Investigator
  
  SHO Ri
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Yamagata University
Heme oxygenase strategy for circumventing environmental changes_fine tuning of activity
- Principal Investigator
  
  MIGITA Taiko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Living organism molecular science
- Research Institution
  Yamaguchi University
Mechanism of heme degradation by heme oxygenase and diversity of heme oxygenase among the various organisms
- Principal Investigator
  
  YOSHIDA Tadashi
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Yamagata University
Mechanism of heme degradation by heme oxygenase and the interaction of heme
- Principal Investigator
  
  YOSHIDA Tadashi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Yamagata University
Relation between the structure and the oxygen acitivation of heme oxygenase reaction
- Principal Investigator
  
  YOSHIDA Tadashi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  YAMAGATA UNIVERSITY
ヘムオキシゲナーゼの構造と機能との関連(特に酸素活性化について)
- Principal Investigator
  
  YOSHIDA Tadashi
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Yamagata University
Mechanism of heme degradation by heme oxygenase
- Principal Investigator
  
  YOSHIDA Tadashi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  Structural biochemistry
- Research Institution
  YAMAGATA UNIVERSITY
Molucular mechanisms of oxygen activation at the three steps in heme oxygenase reaction
- Principal Investigator
  
  YOSHIDA Tadashi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  YAMAGATA UNIVERSITY

All 2023 2022 2021 2020 2013 2012 2011 2005 2004 Other

All Journal Article Presentation

[Journal Article] Protein expresses ey The ho2 gene of the cyane-lacterium Synechocystis sp. pcc 68a3 is a true2005
- Author(s)
  Zhang Xuhong
- Journal Title
  
  FEBS Journal 272
  
  Pages: 1012-1022
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16570108
[Journal Article] Protein expressed by the ho2 gene of the cyanobacterium Synechocystis sp. PCC6803 is a true heme oxygenase2005
- Author(s)
  Zhang X. et al.
- Journal Title
  
  FEBS J. 272
  
  Pages: 1012-1022
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16570108
[Journal Article] Protein expressed by the ho2 gene of the cyanobacterium Synechocystis sp.PCC 6803 is a true heme oxygenase2005
- Author(s)
  Zhang Xuhong
- Journal Title
  
  FEBS Journal 272
  
  Pages: 1012-1022
- Data Source
  KAKENHI-PROJECT-16570108
[Journal Article] Unique features of recombinant heme oxygenase of Drosophila melanogaster compared with those of other heme oxygenases studied2004
- Author(s)
  Zhang Xuhong
- Journal Title
  
  European Journal of Biochemistry 271
  
  Pages: 1713-1724
- Data Source
  KAKENHI-PROJECT-16570108
[Journal Article] Unique feature of recompinant heme oxggenase of Drosophila melanegaster comparea with2004
- Author(s)
  Zhang Xuhong
- Journal Title
  
  European Journal of Biochemietry 271
  
  Pages: 1713-1724
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16570108
[Journal Article] Unique features of recombinant heme oxygenase of Drosophila melanogaster compared with those of other heme oxygenase studied2004
- Author(s)
  Zhang X. et al.
- Journal Title
  
  Eur.J.Biochem 271
  
  Pages: 1713-1724
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16570108
[Presentation] miR-223を用いた口腔がんに対する新規RNAベース治療法の確立に関する研究2023
- Author(s)
  邵力, 張旭紅, 千田邦明, 伊藤吏, 橘寛彦, 惣宇利正善, 今田恒夫
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K08559
[Presentation] 治療用RNAスクリーニングのプラットフォームとしての患者由来腫瘍オルガノイドの確立における課題2023
- Author(s)
  邵力、張旭紅、鈴木潤、渡辺光、塩野知志、千田邦明、伊藤吏、惣宇利正善、今田恒夫
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K09720
[Presentation] miR-223を用いた口腔がんに対する新規RNAベース治療法の確立に関する研究2023
- Author(s)
  邵力、張旭紅、千田邦明、伊藤吏、橘寛彦、惣宇利正善、今田恒夫
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K09720
[Presentation] 治療用RNAのスクリーニングのための患者由来の腫瘍オルガノイドの確立における課題2023
- Author(s)
  邵力, 張旭紅, 鈴木潤, 渡辺光, 塩野知志, 千田邦明, 伊藤吏, 惣宇利正善, 今田恒夫
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20K08559
[Presentation] 薬物反応試験のための患者由来の肺癌オルガノイドモデルの構築2022
- Author(s)
  邵力、張旭紅、鈴木潤、高森聡、塩野知志、惣宇利正善、今田恒夫.
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20K08559
[Presentation] 薬物反応試験のための患者由来の肺癌オルガノイドモデルの構築2022
- Author(s)
  邵力、張旭紅、鈴木潤、高森聡、塩野知志、惣宇利正善、今田恒夫
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K09720
[Presentation] ゲフィチニブ耐性非小細胞肺がん細胞株におけるlncRNA S180122の発現亢進と上皮間葉転換の促進2021
- Author(s)
  1.邵力、張旭紅、鈴木潤、鈴木克幸、高森聡、大泉弘幸、惣宇利正善、今田恒夫
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20K08559
[Presentation] Establishment of Patient-Derived Oral Cancer Organoid Cultures.2020
- Author(s)
  2.Tachibana H, Sho R, Zhang XH, Ozaki H, Koike S, Karakami K, Konta T.
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K08559
[Presentation] LncRNA S180122 modulates EMT in human non-small cell lung cancer cells.2020
- Author(s)
  Sho R, Zhang XH, Suzuki J, Osaki T, Souri M, Konta T.
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K08559
[Presentation] Is microRNA-224 a potential therapeutic target for HCC?2013
- Author(s)
  Zhang XH, Sho R, Watanabe H, et al
- Organizer
  第86回日本生化学会
- Place of Presentation
  パシフィコ横浜（横浜）
- Data Source
  KAKENHI-PROJECT-24590953
[Presentation] Identification of miR-224 target genes and pathways related to hepatocellular carcinoma2012
- Author(s)
  Zhang XH, Sho R, Watanabe H, et al
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場 (福岡)
- Data Source
  KAKENHI-PROJECT-24590953
[Presentation] The Use of RNAi-based Screens to Identify Host Factors Involved in HCV Replication2012
- Author(s)
  Sho R, Zhang XH, Watanabe H, et al
- Organizer
  The 10th JSH Single Topic Conference “Hepatitis C:Best Practice Based on Science”
- Place of Presentation
  KEIO PLAZA HOTEL (Shinjuku, Tokyo)
- Data Source
  KAKENHI-PROJECT-24590953
[Presentation] 反応環境に応答したヘムオキシゲナーゼによるヘム分解の微調整2011
- Author(s)
  高田さゆり・佐藤道比古・張旭紅・右田たい子
- Organizer
  日本生物物理学会第49回年会
- Place of Presentation
  兵庫県立大学姫路書写キャンパス(姫路市)
- Year and Date
  2011-09-18
- Data Source
  KAKENHI-PROJECT-22510232
[Presentation] Fine tuning of the heme catabolism by heme oxygenase in response to the reaction milieu2011
- Author(s)
  高田さゆり・佐藤道比古・張極紅・右田たい子
- Organizer
  日本生物物理学会第49回年会
- Place of Presentation
  兵庫県立大書写キャンパス(姫路市)
- Year and Date
  2011-09-18
- Data Source
  KAKENHI-PROJECT-22510232
[Presentation] ヘムオキシゲナーゼ反応のプロトン・酸素濃度依存性2011
- Author(s)
  高田さゆり・張旭紅・佐藤道比古・右田たい子
- Organizer
  第38回生体分子科学討論会
- Place of Presentation
  筑波大学大学会館(つくば市)
- Year and Date
  2011-06-23
- Data Source
  KAKENHI-PROJECT-22510232
[Presentation] ヘムオキシゲナーゼ反応のプロトン・酸素濃度依存性2011
- Author(s)
  高田さゆり・張極紅・佐藤道比古・右田たい子
- Organizer
  第38回生体分子科学討論会
- Place of Presentation
  筑波大学(つくば市)
- Year and Date
  2011-06-23
- Data Source
  KAKENHI-PROJECT-22510232
[Presentation] ヒト肝癌細胞異種移植モデルを用いたantagomiR-224の抗腫瘍活性の検討
- Author(s)
  邵力,張旭紅, 福田直樹等
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館・グランドプリンスホテル京都, 京都
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-24590953

1. YOSHIDA Tadashi (10004673)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
2. MIGITA Taiko (90159161)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
3. SATO Michihiko (00135344)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
4. SHO Ri (80344787)

# of Collaborated Projects: 4 results

# of Collaborated Products: 13 results
5. FUJII Hiroshi (80228957)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. OZAKI Shinichi (40280581)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. MIGITA Kouto (90116757)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
8. WATANABE Hisayoshi (00332536)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
9. ISHII Rika (60466612)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 鈴木潤 (70533925)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
11. 濱田顕 (80772954)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 千田邦明 (20571665)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. 尾崎司 (60380565)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. OLSOH John S

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Chou Kyokukou 張 旭紅

張 旭紅 チヨウ キヨクコウ

ZHANG Xuhong 張 旭紅

ZHANG Zuhong 張 旭紅

Research Projects

Research Products

Co-Researchers

口腔癌治療用RNA医薬のDDS最適化研究Principal Investigator

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Development of a microRNA-based drug against oral cancerPrincipal Investigator

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[Journal Article] Protein expresses ey The ho2 gene of the cyane-lacterium Synechocystis sp. pcc 68a3 is a true2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Protein expressed by the ho2 gene of the cyanobacterium Synechocystis sp. PCC6803 is a true heme oxygenase2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Protein expressed by the ho2 gene of the cyanobacterium Synechocystis sp.PCC 6803 is a true heme oxygenase2005

Author(s)

Journal Title

Data Source

[Journal Article] Unique features of recombinant heme oxygenase of Drosophila melanogaster compared with those of other heme oxygenases studied2004

Author(s)

Journal Title

Chou Kyokukou 張旭紅

張旭紅チヨウキヨクコウ

ZHANG Xuhong 張旭紅

ZHANG Zuhong 張旭紅