Udaka Keiko 宇高恵子

… Alternative Names

Researcher Number	40263066
Other IDs
External Links
Affiliation (Current)	2019: 高知大学, 教育研究部医療学系基礎医学部門, 教授
Affiliation (based on the past Project Information) *help	2016 – 2019: 高知大学, 教育研究部医療学系基礎医学部門, 教授 2013 – 2015: 高知大学, 医歯学系, 教授 2012 – 2013: 高知大学, 教育研究部医療学系, 教授 2011: 高知大学, 教育研究部・医療学系, 教授 2009: Kochi University, 教育研究部・医療学系, 教授 … More
Review Section/Research Field	Principal Investigator Biological Sciences / Immunology / Basic Section 50020:Tumor diagnostics and therapeutics-related / Applied genomics Except Principal Investigator Biomedical engineering/Biomaterial science and engineering / Virology / Pathobiological dentistry/Dental radiology / Gastroenterology / Infectious disease medicine / Urology … More
Keywords	Principal Investigator MHC / ペプチド / T細胞 / エピトープ / ライブラリー / レパートリー / peptide / 特異性 / トランスレーショナルリサーチ / 免疫学 … More Except Principal Investigator ペプチドワクチン / Th標的ペプチド / 免疫学 / ワクチン / CTL標的ペプチド / 口腔扁平上皮癌 / 細胞傷害性Tリンパ球 / 抗脾腫効果 / 胚中心 / Germinal center / チップ技術 / Class switch recombination / 細胞傷害活性 / ランダムペプチドライブラリー / クラススイッチ領域 / Affinity maturation / ペプチド癌ワクチン / 生体材料 / Bursa Fabricius / 腫瘍特異的Th / ウイルス / 癌 / 前がん状態 / NATURAL KILLER CELL / CD8陽性Tリンパ球 / Immunoglobulin / 腫瘍免疫 / 抗原親和性成熟 / リポソーム / シグナル配列 / 抗原提示 / RETROVIRUS / エクソソーム / IMMUNE PROTECTION / NPハプテン / Tリンパ球 / ヘルパーT細胞 / がんワクチン / 感染症治療学 / LAK細胞 / 低酸素 / CD4陽性Tリンパ球 / 高親和性 / Gagシグナル配列 / Env抗原 / NK細胞 / 抗腫瘍免疫 / ナノ医療 / Gag抗原 / PCR method / 感染症 / PCR法 / クラススイッチ組換え / 人口ペプチド設計 / 免疫グロブリン / HIF-1α / FBL-3腫瘍 / 抑制性T細胞 / サイトゾルデリバリー / リンパ球幼若化試験 / モロニ-ウイルス / 細胞傷害性T細胞 / 自己免疫反応 / 抗原エピトープ / 炭酸脱水酵素 / PSA / Gene conversion / ナチュラルキラー / 自己免疫性膵炎 / HLA / pH応答性高分子 / フレンドウイルス / がん治療 / CYTOTOXICITY / 薬物送達システム / ペプチド免疫 / 細胞傷害反応 / Point mutation / 膜融合 / 抗原親和性 / システイン含有ペプチド / 抗体遺伝子 / ブルサ / モデルマウス / 動物 / miRNA / TLYMPHOCYTE / クラススイツチ組換え / 制御性T細胞 / IL-2産生 / ナノワクチン / 腫瘍特異的CTL / 前立腺癌 / 血管内皮細胞 / FITCハプテン / バイオマーカー / 点突然変異 / 組換えワクシニアウイルス / 腫瘍拒絶 / アジュバント / エピトープ / 抗腫瘍効果 / 免疫抑制解除 / 感染防御 / 樹状細胞 / 細胞質デリバリー / VACCINE / がん抗原ペプチド / レトロウイルス / がん免疫療法 / LEUKEMIA / ナノバイオ / 人工ペプチド設計 / EPITOPE / 体細胞突然変異 / 白血病 / 遺伝子変換 / TGF-β / env領域ペプチド / EBV / ペプチド / CTLエピトープ / 抗体 Less

腫瘍血管内皮細胞の抗原提示能を活かした次世代がん免疫療法の基盤研究Principal InvestigatorOngoing
- Principal Investigator
  
  宇高恵子
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kochi University
ヘルパーT細胞への抗原提示に注目した腫瘍免疫反応の場における血管内皮細胞の解析Ongoing
- Principal Investigator
  
  清水健之
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kochi University
Development of Zika fever- and AIDS-peptide vaccine using next generation chip, T-ISAACOngoing
- Principal Investigator
  
  村口篤
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Infectious disease medicine
- Research Institution
  University of Toyama
新規診断・治療法の開発に向けた口腔扁平上皮癌細胞由来エクソソームの解析Ongoing
- Principal Investigator
  
  山本哲也
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Kochi University
腫瘍におけるネオ・セルフ生成機構Principal InvestigatorOngoing
- Principal Investigator
  
  宇高恵子
- Project Period (FY)
  2016 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kochi University
Fabrication of highly active antigen nanocarriers by integration of immunity-inducing functions and their application to cancer immunotherapy
- Principal Investigator
  
  YUBA Eiji
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Osaka Prefecture University
合目的機能の統合によるオールインワンナノメディシンの開発と非侵襲がん治療への展開
- Principal Investigator
  
  河野健司
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Osaka Prefecture University
血管内皮細胞ＭＨＣ分子の抗原提示能の解析と臨床応用Principal Investigator
- Principal Investigator
  
  宇高恵子
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kochi University
Effects of hypoxic environment and HIF-1 on antitumor immune response of oral squamous cell carcinoma
- Principal Investigator
  
  YAMAMOTO TETSUYA
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Kochi University
自己免疫性膵炎における特異的免疫応答の検討
- Principal Investigator
  
  西森功
- Project Period (FY)
  2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kochi University
Construction of a system to develop immunotherapy by exploiting the computational algorithm to identify HLA-binding peptides.Principal Investigator
- Principal Investigator
  
  UDAKA Keiko
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied genomics
- Research Institution
  Kochi University
進行・再発前立腺癌に対するPSAペプチド癌ワクチン及び新規アジュバントの開発
- Principal Investigator
  
  飯山達雄
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Urology
- Research Institution
  Kochi University
小児の難治性EBウイルス感染症に対する効率的ペプチドワクチンの新規開発
- Principal Investigator
  
  細川卓利
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pediatrics
- Research Institution
  Kochi University
HLA結合性ペプチド予測による免疫標的探索法の開発Principal Investigator
- Principal Investigator
  
  宇高恵子
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kochi University
ゲノムワイドのMHC class I結合性ペプチド探索自動化データベースPrincipal Investigator
- Principal Investigator
  
  宇高恵子
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  高知医科大学
MHC class I分子結合性ガン抗原の探索とガン抗原認識機構の研究Principal Investigator
- Principal Investigator
  
  宇高恵子
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
MECHANISMS OF PROTECTION AGAINST RETROVIRAL INFECTIONS INDUCED WITH A SINGLE-EPITOPE CD4^+ T-CELL VACCINE
- Principal Investigator
  
  MIYAZAWA Masaaki
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  KINKI UNIVERSITY
T細胞抗原の特異性の由来についてPrincipal Investigator
- Principal Investigator
  
  宇高恵子
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyoto University
腫癌拒絶抗原の解析とペプチドワクチンの設計
- Principal Investigator
  
  山岸秀夫
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
MHCとペプチドの相補的会合の研究Principal Investigator
- Principal Investigator
  
  宇高恵子
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
ペプチドライブラリーを用いたCTLの特異性の解析Principal Investigator
- Principal Investigator
  
  宇高恵子
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
Specificity analysis of cytotoxic T lymphocytes with peptide libraries.Principal Investigator
- Principal Investigator
  
  UDAKA Keiko
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  KYOTO UNIVERSITY
Studies on chicken immunoglobulin gene moditication and attinity maturation
- Principal Investigator
  
  YAMAGISHI Hideo
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  Health Research Foundation
  Kyoto University
腫瘍拒絶抗原の解析とペプチドワクチンの検討
- Principal Investigator
  
  YAMAGISHI Hideo
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
ペプチドライブラリーを用いたMHC‐ペプチド複合体の相補的安定化要因の解析Principal Investigator
- Principal Investigator
  
  宇高恵子
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
ペプチドライブラリーを用いたCTLエピトープの解析Principal Investigator
- Principal Investigator
  
  宇高恵子
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
ペプチドライブラリーを用いたCTLエピトープの解析Principal Investigator
- Principal Investigator
  
  宇高恵子
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
ペプチドライブラリーを用いたMHC-ペプチド複合体の相補的安定化要因の解析Principal Investigator
- Principal Investigator
  
  宇高恵子
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
任意のT細胞エピトープ同定法の開発Principal Investigator
- Principal Investigator
  
  UDAKA Keiko
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  KYOTO UNIVERSITY

All 2018 2017 2016 2015 2012 2011 2010 2009 2008 2007 2004

All Journal Article Presentation

[Journal Article] Knockout of the interleukin-36 receptor protects against renal ischemia-reperfusion injury by reduction of proinflammatory cytokines2018
- Author(s)
  Nishikawa H, Taniguchi Y, Matsumoto T, Arima N, Masaki M, Shimamura Y, Inoue K, Horino T, Fujimoto S, Ohko K, Komatsu T, Udaka K, Sano S, Terada Y.
- Journal Title
  
  Kidney International
  
  Volume: 93 Pages: 599-614
- DOI
  10.1016/j.kint.2017.09.017
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19491, KAKENHI-PLANNED-16H06498, KAKENHI-PROJECT-16K14611
[Journal Article] Therapy with transcutaneous administration of imiquimod combined with oral administration of sorafenib suppresses renal cell carcinoma growing in an orthotopic mouse model2017
- Author(s)
  Karashima Takashi、Udaka Keiko、Niimura Mayumi、Suzuki Katsuhide、Osakabe Hiroto、Shimamoto Tsutomu、Fukata Satoshi、Inoue Keiji、Kuroda Naoto、Seiki Motoharu、Shuin Taro
- Journal Title
  
  Oncol. Lett.
  
  Volume: 14 Pages: 1162-1166
- DOI
  10.3892/ol.2017.6235
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06498, KAKENHI-PROJECT-15H03024, KAKENHI-PROJECT-15K10593
[Journal Article] がん免疫療法　-がん完治に向けての新たな治療法の探索-2017
- Author(s)
  宇高恵子
- Journal Title
  
  日本臨床
  
  Volume: 75 Pages: 170-173
- Data Source
  KAKENHI-PLANNED-16H06498
[Journal Article] 免疫機構によるがん細胞攻撃の仕組み2017
- Author(s)
  宇高恵子
- Journal Title
  
  日本臨床
  
  Volume: 75 Pages: 170-173
- Data Source
  KAKENHI-PROJECT-15H03024
[Journal Article] Improvement of peptide-based tumor immunotherapy using pH-sensitive fusogenic polymer-modified liposomes2016
- Author(s)
  Y. Yoshizaki, E. Yuba, T. Komatsu, K. Udaka, A. Harada, K. Kono
- Journal Title
  
  Molecules
  
  Volume: 21 Pages: 1284-1284
- DOI
  10.3390/molecules21101284
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06498, KAKENHI-PROJECT-15H03024, KAKENHI-PROJECT-15J12180, KAKENHI-PROJECT-16K14611, KAKENHI-PROJECT-26242049
[Journal Article] MHC: a Meta aproach to predict peptides binding to MHC molecules2010
- Author(s)
  Hu, X., Zhou, W., Udaka K., Mamitsuka H., Zhu S., Meta
- Journal Title
  
  Nucleic Acids Res (Epub ahead of print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19510209
[Journal Article] Lipid-mediated presentation of MHC clas II molecules guides thymocytes to the CD4 lineage2009
- Author(s)
  Komaniwa S., Hayashi H., Kawamoto H., Sato S.B., Ikawa T., Katsura Y., Udaka K
- Journal Title
  
  Eur J Immunol 39
  
  Pages: 1-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19510209
[Journal Article] Wilms' tumor 1 gene expression is increased in hepatocellular carcinoma and associated with por prognosis2008
- Author(s)
  Sera T., Hiasa Y., Mashiba T., Tokumoto Y., Hiroka M., Konishi I., Matsuura B., Michitaka K., Udaka K., Onji M
- Journal Title
  
  Eur J Cancer 44(4)
  
  Pages: 600-608
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19510209
[Journal Article] Identification of a WT1 protein-derived peptide, WT1187 as an HLA-A*0206-restricted, WT1-specific CTL epitope2008
- Author(s)
  Li Z., Oka Y., Tsuboi A., Kawakami Y., Udaka K., Oji Y., Sugiyama H. (計20名中17番目)
- Journal Title
  
  Microbiology and Immunology 52(1)
  
  Pages: 551-558
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19510209
[Journal Article] Wilms' tumor gene WT1 peptide-based immunotherapy induced a minimal response in a patient with advanced therapy-resistant multiple myeloma2007
- Author(s)
  Tsuboi A., Oka Y., Udaka K., Kawase I., Sugiyama H. (計21名中19番目
- Journal Title
  
  Int J Hematol 86(5)
  
  Pages: 414-417
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19510209
[Journal Article] Potent CTL induction by a whole cell Pertussis vaccine in anti-tumor peptide immunotherapy2007
- Author(s)
  Yano A, Udaka K, et. al.
- Journal Title
  
  Microbiology and Immunology 51
  
  Pages: 689-699
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19510209
[Journal Article] WT1(Wilms' tumor 1)peptide immunotherapy for renal cell carci noma2007
- Author(s)
  Iiyama Y, Udaka K, et. al.
- Journal Title
  
  Microbiology and Immunology 51
  
  Pages: 519-530
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659415
[Journal Article] WT1(Wilms' tumor 1) peptide immunotherapy for renal cell carcinoma2007
- Author(s)
  Iiyama Y, Udaka K, et. al.
- Journal Title
  
  Microbiology and Immunology 51
  
  Pages: 519-530
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19510209
[Journal Article] Potent CTL induction by a whole cell Pertussis vacine in anti-tumor peptide immunotherapy2007
- Author(s)
  Yano A., Komatsu T., Ishibashi M., Udaka K
- Journal Title
  
  Microbiol Immunol 51(7)
  
  Pages: 685-699
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19510209
[Journal Article] WT1 (Wilms' tumor 1) peptide immunotherapy for renal cell carcinoma2007
- Author(s)
  Iiyama T., Takeda S., Udaka K., Takeuchi T., Adachi Y.C., Shuin T., Ohtsuki Y., Oka Y., Tsuboi A., Nakatsuka S., Eliseeva O.A., Oji Y., Nakajima H., Kawakami M., Nishida S., Shirakata T., Sugiyama H
- Journal Title
  
  Microbiol Imunol 51(5)
  
  Pages: 519-530
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19510209
[Journal Article] WT1 peptide-based immunotherapy for patients with lung cancer : Report of two cases.2004
- Author(s)
  A.Tsuboi, K.Udaka, H.Sugiyama., et al.
- Journal Title
  
  Microbiol Immunol 48
  
  Pages: 175-184
- Data Source
  KAKENHI-PROJECT-16014217
[Journal Article] Induction of WT1(Wilms' tumor gene)-specific cytotoxic T lymphocytes by WT1 peptide vaccine and the resultant cancer regression.2004
- Author(s)
  Yoshihiro Oka, K.Udaka, H.Sugiyama., et al.
- Journal Title
  
  Proc Natl Acad Sci USA 101
  
  Pages: 13885-13890
- Data Source
  KAKENHI-PROJECT-16014217
[Presentation] Topical application of nano-sized, bactericidal polymer particles ameliorates hapten-induced dermatitis.2017
- Author(s)
  Udaka K, Kasai M, Ayano Kawaguchi, Kamijima R, Matsuzaki S, Suzuki K, Yamamoto M, Sano S, Shirotake S
- Organizer
  日本研究皮膚科学会第42回年次学術大会・総会
- Data Source
  KAKENHI-PROJECT-17H04219
[Presentation] Topical application of nano-sized, bactericidal polymer particles ameliorates hapten-induced dermatitis.2017
- Author(s)
  Udaka K, Kasai M, Kawaguchi A, Kamijima R, Matsuzaki S, Suzuki K, Yamamoto M, Sano S, Shirotake S
- Organizer
  日本研究皮膚科学会第42回年次学術大会・総会
- Data Source
  KAKENHI-PLANNED-16H06498
[Presentation] pH応答性高分子修飾リポゾームの抗原ペプチドデリバリーキャリアとしての機能2017
- Author(s)
  弓場英司、能崎優太、原田敦史、宇高恵子、西村泰治、河野健司
- Organizer
  第33回日本ＤＤＳ学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04219
[Presentation] Extravasation of CTLs occurs by recognizing the MHC-peptide complexes cross-presented by vascular endothelial cells.2017
- Author(s)
  Komatsu T, Iwade R, Kijima M, Sato T, Udaka K
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PLANNED-16H06498
[Presentation] Novel WT1 peptide vaccination for newly diagnosed malignant gliomas2017
- Author(s)
  Y. Kawasaki, K. Udaka, T. Ueba
- Organizer
  The 36th Sapporo International cancer Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03024
[Presentation] Construction of a TAP deficient HLA class I-binding assay system with the use of CRISPR/Cas9 system2017
- Author(s)
  Shimizu T, Komatsu T, Udaka K
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04219
[Presentation] Novel WT1 peptide vaccination for newly diagnosed malignant gliomas.2017
- Author(s)
  Kawasaki Y, Udaka K, Ueba T
- Organizer
  The 36th Sapporo Intrnational cancer Symposium
- Data Source
  KAKENHI-PROJECT-17H04219
[Presentation] 腫瘍に対するＴ細胞戦略2017
- Author(s)
  宇高恵子
- Organizer
  第65回ＮＰＯ法人日本口腔科学会中国・四国地方部会
- Invited
- Data Source
  KAKENHI-PLANNED-16H06498
[Presentation] A phase I study of novel multi-HLA binding peptides and a new combination of immune adjutants against solid tumors2017
- Author(s)
  H. Matsui, S. Hazama, K. Tamada, K. Udaka, Y. Koki, T. Uematsu, H. Arima, H. Furukawa, T. Miyakawa, S. Doi, M. Nakajima, M. Kitahara, S. Kanekiyo, Y. Tokumitsu, M. Iida, Y. Tokuhisa, K. Sakamoto, N. Suzuki, S. Takeda, S. Yamamoto, S. Yoshino, T. Ueno, H. Nagano
- Organizer
  American Society of Clinical Oncology (ASCO) 2017 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03024
[Presentation] A phase I study of novel multi-HLA binding peptides and a new combination of immune adjutants against solid tumors.2017
- Author(s)
  Matsui H, Hazama S, Tamada K, Udaka K, Koki Y, Uematsu T, Arima H, Furukawa H, Miyakawa T, Doi S, Nakajima M, Kitahara M, Kanekiyo S, Tokumitsu Y, Iida M, Tokuhisa Y, Sakamoto K, Suzuki N, Takeda S, Yamamoto S, Yoshino S, Ueno T, Nagano H
- Organizer
  2017 American Society of Clinical Oncology Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04219
[Presentation] Extravasation of CTLs occurs by recognizing the MHC-peptide complexes cross-presented by vascular endothelial cells.2017
- Author(s)
  Komatsu T, Iwade R, Kijima M, Sato T, Udaka K
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04219
[Presentation] Construction of a TAP deficient HLA class I-binding assay system with the use of CRISPR/Cas9 system2017
- Author(s)
  T. Shimizu, T. Komatsu, K.Udaka
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-15H03024
[Presentation] Construction of a TAP deficient HLA class I-binding assay system with the use of CRISPR/Cas9 system2017
- Author(s)
  Shimizu T, Komatsu T, Udaka K
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PLANNED-16H06498
[Presentation] pH応答性高分子修飾リポゾームの抗原ペプチドデリバリーキャリアとしての機能2017
- Author(s)
  弓場英司、能崎優太、原田敦史、宇高恵子、西村泰治、河野健司
- Organizer
  第33回日本ＤＤＳ学会学術集会
- Data Source
  KAKENHI-PLANNED-16H06498
[Presentation] Application with nano-sized cyanoacryl particles ameliorates experimental dermatitis through the bacteriocidal activity.2017
- Author(s)
  Kasai M, Sano S, Udaka K
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04219
[Presentation] Application with nano-sized cyanoacryl particles ameliorates experimental dermatitis through the bacteriocidal activity2017
- Author(s)
  M. Kasai, S. Sano, K. Udaka
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-15H03024
[Presentation] Topical application of nano-sized, bactericidal polymer particles ameliorates hapten-induced dermatitis2017
- Author(s)
  K. Udaka, M. Kasai, A. Kawaguchi, R. Kamijima, S. Matsuzaki, K. Suzuki, M. Yamamoto, S. Sano, S. Shirotake
- Organizer
  日本研究皮膚科学会第42回年次学術大会・総会
- Data Source
  KAKENHI-PROJECT-15H03024
[Presentation] Extravasation of CTLs occurs by recognizing the MHC-peptide complexes cross-presented by vascular endothelial cells2017
- Author(s)
  T. Komatsu, R. Iwade, M. Kijima, T. Sato, K. Udaka
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-15H03024
[Presentation] Novel WT1 peptide vaccination for newly diagnosed malignant gliomas.2017
- Author(s)
  Kawanishi Y, Udaka K, Ueba T
- Organizer
  The 36th Sapporo Intrnational cancer Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06498
[Presentation] pH応答性多糖修飾リポソームの抗原ペプチドデリバリキャリアとしての機能2017
- Author(s)
  弓場英司，能﨑優太，原田敦史，宇高恵子，西村泰治，河野健司
- Organizer
  第33回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-15H03024
[Presentation] 腫瘍に対するＴ細胞戦略2017
- Author(s)
  宇高恵子
- Organizer
  第65回ＮＰＯ法人日本口腔科学会中国・四国地方部会
- Data Source
  KAKENHI-PROJECT-15H03024
[Presentation] 腫瘍に対するＴ細胞戦略2017
- Author(s)
  宇高恵子
- Organizer
  第65回ＮＰＯ法人日本口腔科学会中国・四国地方部会
- Data Source
  KAKENHI-PROJECT-17H04219
[Presentation] A phase I study of novel multi-HLA binding peptides and a new combination of immune adjutants against solid tumors.2017
- Author(s)
  Matsui H, Hazama S, Tamada K, Udaka K, Koki Y, Uematsu T, Arima H, Furukawa H, Miyakawa T, Doi S, Nakajima M, Kitahara M, Kanekiyo S, Tokumitsu Y, Iida M, Tokuhisa Y, Sakamoto K, Suzuki N, Takeda S, Yamamoto S, Yoshino S, Ueno T, Nagano H
- Organizer
  Annual Meeting of the American Society of Clinical Oncology（ASCO）
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06498
[Presentation] 血管内皮細胞のＨＬＡクラスＩＩ発現は、Ｔ細胞浸潤及び膵腫瘍に対する傷害活性と関連する2016
- Author(s)
  宇高恵子、木岐　淳、西森　功、西原利治、小松利広、西岡千恵、鈴木勝英
- Organizer
  第８回血液疾患免疫療法学会学術集会
- Place of Presentation
  北海道大学（北海道札幌市）
- Year and Date
  2016-09-03
- Data Source
  KAKENHI-PLANNED-16H06498
[Presentation] 血管内皮細胞のＨＬＡクラスＩＩ発現は、Ｔ細胞浸潤及び膵腫瘍に対する傷害活性と関連する2016
- Author(s)
  宇高恵子、木岐　淳、西森　功、西原利治、小松利広、西岡千恵、鈴木勝英
- Organizer
  第８回血液疾患免疫療法学会
- Place of Presentation
  北海道大学(北海道札幌市）
- Data Source
  KAKENHI-PROJECT-15H03024
[Presentation] Ｔopical treatment with nano-sized particles of cyanoacryl polymer ameliorates experimental dermatitis through backteriocidal effect.2016
- Author(s)
  Yamamoto M, Kasai M, Kawaguchi A, Kamijima R, Suzuki K, Shirotake S, Sano S, Udaka K.
- Organizer
  日本研究皮膚科学会第４１回年次学術大会総会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-12-09
- Data Source
  KAKENHI-PLANNED-16H06498
[Presentation] 血管内皮細胞のクロスプレゼンテーションによるＣＴＬの固形腫瘍への抗原特異的浸潤2016
- Author(s)
  岩出良介、横山水紀、小松利広、木嶋美香、笠井道之、清水健之、佐藤健人、宇高恵子
- Organizer
  第１５回四国免疫フォーラム
- Place of Presentation
  高知大学医学部(高知県南国市)
- Data Source
  KAKENHI-PROJECT-15H03024
[Presentation] がん免疫療法の開発戦略　-抗原提示の視点から-2016
- Author(s)
  宇高恵子
- Organizer
  日本臨床麻酔学会第３６回大会
- Place of Presentation
  ザ　クラウンパレス新阪急高知（高知県高知市）
- Year and Date
  2016-11-03
- Invited
- Data Source
  KAKENHI-PLANNED-16H06498
[Presentation] Topical treatment with nano-sized particles of cyanoacryl polymer ameliorates experimental dermatitis through backteriocidal effect.2016
- Author(s)
  Yamamoto M, Kasai M, Kawaguchi A, Kamijima R, Suzuki K, Shirotake S, Sano S, Udaka K
- Organizer
  日本研究皮膚科学会第４１回年次学術大会・総会
- Place of Presentation
  仙台国際センター(宮城県仙台市)
- Year and Date
  2016-12-09
- Data Source
  KAKENHI-PROJECT-15H03024
[Presentation] がん免疫療法の開発戦略　-抗原提示の視点から-2016
- Author(s)
  宇高　恵子
- Organizer
  日本臨床麻酔学会第３６回大会
- Place of Presentation
  高知県立県民文化ホール(高知県高知市)
- Invited
- Data Source
  KAKENHI-PROJECT-15H03024
[Presentation] How do antigen specific DC4 and CD8 T cells contribute to the development of anexperimental contact dermatitis?2016
- Author(s)
  Okunaga I, Shimizu T, Udaka K
- Organizer
  第45回日本免疫学会学術集会
- Place of Presentation
  沖縄コンベンションセンター（沖縄県宜野湾市）
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PLANNED-16H06498
[Presentation] 血管内皮細胞のクロスプレゼンテーションによるCTLの固形腫瘍への抗原特異的浸潤2016
- Author(s)
  岩出良介、横山水紀、小松利広、木嶋美香、笠井道之、清水健之、佐藤健人、宇高恵子
- Organizer
  第15回四国免疫フォーラム
- Place of Presentation
  高知県南国市、高知大学医学部
- Year and Date
  2016-06-25
- Data Source
  KAKENHI-PROJECT-26242049
[Presentation] 血管内皮細胞のHLAクラスⅡ発現は、T細胞浸潤及び膵腫瘍に対する傷害活性と関連する2016
- Author(s)
  宇高恵子、木岐淳、西森功、西原利治、小松利広、西岡千恵、鈴木勝英
- Organizer
  第8回血液疾患免疫療法学会
- Place of Presentation
  北海道札幌市、北海道大学
- Year and Date
  2016-09-03
- Data Source
  KAKENHI-PROJECT-26242049
[Presentation] Cross-presentation of tumor antigen by endothelial cells promotes infiltration of tumor specific CTLs.2016
- Author(s)
  Komatsu T, Iwade,R, Sato T, Udaka K
- Organizer
  第45回日本免疫学会学術集会
- Place of Presentation
  沖縄コンベンションセンター（沖縄県宜野湾市）
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PLANNED-16H06498
[Presentation] がん免疫療法の開発戦略 -抗原提示の視点から-2016
- Author(s)
  宇高恵子
- Organizer
  日本臨床麻酔学会第36回大会
- Place of Presentation
  高知県高知市、高知県立県民文化ホール
- Year and Date
  2016-11-04
- Invited
- Data Source
  KAKENHI-PROJECT-26242049
[Presentation] Cross-presentation of tumor antigen by endothelial cells promotes infiltration of tumor specific CTLs2016
- Author(s)
  Komatsu T, Iwade　R, Sato T, Udaka K
- Organizer
  第45回日本免疫学会学術集会
- Place of Presentation
  沖縄コンベンションセンター(沖縄県宜野湾市)
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-15H03024
[Presentation] How do antigen specific DC4 and CD8 T cells contribute to the development of anexperimental contact dermatitis?2016
- Author(s)
  Okunaga I, Shimizu T, Udaka K
- Organizer
  第45回日本免疫学会学術集会
- Place of Presentation
  沖縄コンベンションセンター(沖縄県宜野湾市)
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-15H03024
[Presentation] HLA class II-binding peptides exhibit more promiscuous binding to allomorphs than the HLA class I-binding peptides2015
- Author(s)
  Udaka K, Kasajima R, Chi S, Arima N, Komatsu T
- Organizer
  第44回日本免疫学会学術集会
- Place of Presentation
  札幌、札幌コンベンションセンター
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-15H03024
[Presentation] 血管内皮細胞による腫瘍細胞の取り込みに関わるopsonin活性について2015
- Author(s)
  小松利広、宇高恵子
- Organizer
  第１４回四国免疫フォーラム
- Place of Presentation
  松山、愛媛大学
- Year and Date
  2015-06-20
- Data Source
  KAKENHI-PROJECT-15H03024
[Presentation] Presentation of tumor antigens in the context of MHC class II molecules by the endothelial cells in solid tumors grown in vivo2015
- Author(s)
  Udaka K, Komatsu T, Ichikawa Y, Kuroe S
- Organizer
  ICCIM2015 International Conference of Cancer Immunotherapy and Macrophages 2015(がん免疫療法・マクロファージ国際会議2015)
- Place of Presentation
  東京、東京大学
- Year and Date
  2015-07-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03024
[Presentation] A minimal influence of glycosylation of ganglioside on the in vivo Th1-dominant responses in mouse2012
- Author(s)
  UDAKA K　et al.
- Organizer
  第４１回日本免疫学会学術集会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2012-12-05
- Data Source
  KAKENHI-PUBLICLY-23133505
[Presentation] 腫瘍抗原の提示とＴ細胞の浸潤機構2012
- Author(s)
  宇高恵子　他
- Organizer
  第22回ＫＴＣＣ（kyoto T Cell Conference）
- Place of Presentation
  京都市和順会館
- Year and Date
  2012-07-06
- Data Source
  KAKENHI-PUBLICLY-23133505
[Presentation] 悪性腫瘍のペプチド免疫療法-なりたちと展望-2012
- Author(s)
  宇高恵子
- Organizer
  日本組織適合性学会近畿地方会
- Place of Presentation
  参天製薬株式会社本社(大阪府)(招待講演)
- Year and Date
  2012-02-05
- Data Source
  KAKENHI-PUBLICLY-23133505
[Presentation] 固形腫瘍における組織抗原の提示機構2012
- Author(s)
  宇高恵子　他
- Organizer
  第16回日本がん免疫学会
- Place of Presentation
  北海道大学
- Year and Date
  2012-07-26
- Data Source
  KAKENHI-PUBLICLY-23133505
[Presentation] How do T cells find their way into solid tumors?2011
- Author(s)
  宇高恵子
- Organizer
  日本がん免疫学会
- Place of Presentation
  千里ライフサイエンスセンター(大阪府)(シンポジウム)
- Year and Date
  2011-07-01
- Data Source
  KAKENHI-PUBLICLY-23133505
[Presentation] 自己免疫性膵炎における制御性t細胞とHLA-DRB1*0405結合-炭酸脱水酵素IVペプチドに対する細胞性免疫応答の検討2009
- Author(s)
  麻植啓輔木岐淳、耕崎拓大、西森功、宇高恵子
- Organizer
  第46回日本消化器学会総会
- Place of Presentation
  松山
- Data Source
  KAKENHI-PROJECT-19510209
[Presentation] 慢性C型肝炎に対するペプチド免疫療法の開発2009
- Author(s)
  宇高恵子
- Organizer
  四国免疫フォーラム
- Place of Presentation
  香川県木田郡
- Year and Date
  2009-06-27
- Data Source
  KAKENHI-PROJECT-19510209
[Presentation] クラスI結合性ペプチドの計算予測を活用した、がんの免疫療法の開発シンポジウム「理論解析と実験から見出される生物物理学」2008
- Author(s)
  宇高恵子
- Organizer
  日本生物物理学会第46回年会
- Place of Presentation
  福岡、福岡国際会議場
- Year and Date
  2008-12-03
- Data Source
  KAKENHI-PROJECT-19510209
[Presentation] HLAクラスI結合性ペプチドの計算予測を活用した、がんの免疫療法の開発シンポジウム「理論解析と実験から見出される生物理学」2008
- Author(s)
  宇高恵子
- Organizer
  日本生物理学会第46回年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-19510209
[Presentation] 抗腫瘍ペプチド免疫療法における百日咳ワクチンのctl誘導活性2007
- Author(s)
  矢野有紗、宇高恵子, 他
- Organizer
  第37回日本免疫学会総会
- Place of Presentation
  東京
- Year and Date
  2007-11-22
- Data Source
  KAKENHI-PROJECT-19510209
[Presentation] Designing T cell epitope peptides that bind promiscuously to several HLA class I molecules2007
- Author(s)
  宇高恵子, 他
- Organizer
  日本生物物理学会第45回年会
- Place of Presentation
  横浜
- Year and Date
  2007-12-21
- Data Source
  KAKENHI-PROJECT-19510209
[Presentation] 抗腫瘍ペプチド免疫療法における百日咳ワクチンのCTL誘導活性2007
- Author(s)
  矢野有紗, 小松利広, 宇高恵子
- Organizer
  第37回日本免疫学会総会
- Place of Presentation
  東京都港区・グランドプリンスホテル新高輪
- Year and Date
  2007-11-22
- Data Source
  KAKENHI-PROJECT-19510209
[Presentation] A mouse model of peptide immunotherapy for hepatitis C Virus2007
- Author(s)
  KATAOKA S., UDAKA K., et al
- Organizer
  第37回日本免疫学会総会
- Place of Presentation
  東京
- Year and Date
  2007-11-20
- Data Source
  KAKENHI-PROJECT-19510209
[Presentation] Peg-IFNリバビリン併用療法後の新しい免疫療法の開発をめざして-ペプチドワクチン-2007
- Author(s)
  日浅陽一、眞柴寿枝、宇高恵子、恩地森一
- Organizer
  日本インターフェロンサイトカイ学会シンポジウム
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19510209
[Presentation] A mouse model of peptide immunotherapy for hepatitis C Virus2007
- Author(s)
  Kataoka S, Udaka K., et. al.
- Organizer
  第37回日本免疫学会総会
- Place of Presentation
  東京都港区・グランドプリンスホテル新高輪
- Year and Date
  2007-11-20
- Data Source
  KAKENHI-PROJECT-19510209
[Presentation] Designing T cell epitope peptides that bind promiscuously to several HLA class I molecules2007
- Author(s)
  Udaka K, et. al.
- Organizer
  日本生物物理学会第45回年会
- Place of Presentation
  神奈川県横浜市・パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-19510209

1. YAMAGISHI Hideo (90025429)

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2. YAMAMOTO TETSUYA (00200824)

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3. SASABE Eri (40363288)

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4. KITAMURA Naoya (70351921)

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5. YUBA Eiji (80582296)

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7. YAMADA Tomohiro (60335619)

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8. RI Yasuhiro (70587526)

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10. EKINO Shigeo (30125273)

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33. 小松利広 (90598517)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
34. KURODA Naoto

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. 辛島尚

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. 島村芳子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Udaka Keiko 宇高 恵子

UDAKA Keiko 宇高 恵子

宇高 恵子 ウダカ ケイコ

Research Projects

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腫瘍血管内皮細胞の抗原提示能を活かした次世代がん免疫療法の基盤研究Principal InvestigatorOngoing

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ヘルパーT細胞への抗原提示に注目した腫瘍免疫反応の場における血管内皮細胞の解析Ongoing

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Development of Zika fever- and AIDS-peptide vaccine using next generation chip, T-ISAACOngoing

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新規診断・治療法の開発に向けた口腔扁平上皮癌細胞由来エクソソームの解析Ongoing

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腫瘍におけるネオ・セルフ生成機構Principal InvestigatorOngoing

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血管内皮細胞ＭＨＣ分子の抗原提示能の解析と臨床応用Principal Investigator

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Construction of a system to develop immunotherapy by exploiting the computational algorithm to identify HLA-binding peptides.Principal Investigator

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HLA結合性ペプチド予測による免疫標的探索法の開発Principal Investigator

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Udaka Keiko 宇高恵子

UDAKA Keiko 宇高恵子

宇高恵子ウダカケイコ