KOBAYASHI EIJI 小林栄治

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KOBAYASHI Eiji 小林栄治

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Researcher Number	70459733
Other IDs
Affiliation (Current)	2025: 富山大学, 学術研究部医学系, 教授
Affiliation (based on the past Project Information) *help	2024: 富山大学, 学術研究部医学系, 教授 2019 – 2023: 富山大学, 学術研究部医学系, 助教 2012 – 2018: 富山大学, 大学院医学薬学研究部(医学), 助教
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Tumor therapeutics / Infectious disease medicine Except Principal Investigator Infectious disease medicine / Basic Section 49070:Immunology-related / Basic Section 54030:Infectious disease medicine-related / Tumor immunology
Keywords	Principal Investigator がん免疫 / T細胞受容体 / T細胞 / 抗原 / キメラ抗原受容体 / 腫瘍 / 抗原同定 / TCR / Treg / 制御性T細胞 … More / キメラ受容体 / アポトーシス / C型肝炎ウイルス / Cytotoxic T lymphocyte / ペプチドワクチン … More Except Principal Investigator T細胞受容体 / リンパ球チップ / cis相互作用 / ペプチド/MHC複合体 / 主要組織適合遺伝子複合体 / 抗原同定 / 次世代型免疫治療 / TCR遺伝子治療 / TCR様抗体 / 次世代型免疫療法 / ウイルス感染症 / チップ技術 / ペプチドワクチン / 感染症治療学 / T Cell Receptor / T cell receptor / 抗体 / 癌治療 / 感染症 / Ｔ細胞受容体 / Ｔリンパ球 / 個の免疫 / 免疫治療 / Tリンパ球 / がん特異的T細胞 / 抗原特異的T細胞 / 細胞チップ / 細胞免疫 Less

がん治療へ向けたサポートCARによる革新的なT細胞受容体療法の開発Principal Investigator
- Principal Investigator
  
  小林栄治
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  University of Toyama
単一T細胞上でのTCRとp/MHCの相互作用を用いたTCR抗原同定法の開発
- Principal Investigator
  
  岸裕幸
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  University of Toyama
Development of antigen identification system of tumor-infiltrating lymphocytesPrincipal Investigator
- Principal Investigator
  
  Kobayashi Eiji
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  University of Toyama
新型ウイルス感染症を標的とした新たな免疫治療法確立のための基盤研究
- Principal Investigator
  
  村口篤
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  University of Toyama
Identification of antigens of tumor-infiltrated regulatory T cells and analysis of tumor suppression systems based on the antigensPrincipal Investigator
- Principal Investigator
  
  Kobayashi Eiji
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  University of Toyama
Development of Zika fever- and AIDS-peptide vaccine using next generation chip, T-ISAAC
- Principal Investigator
  
  Muraguchi Atsushi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Infectious disease medicine
- Research Institution
  University of Toyama
Development of an innovative lymphocyte chip to establish personalized immuno-therapy for infectious diseases
- Principal Investigator
  
  MURAGUCHI Atsushi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Infectious disease medicine
- Research Institution
  University of Toyama
抗体療法とT細胞療法を融合したハイブリッド型がん免疫療法の有効性の検証Principal Investigator
- Principal Investigator
  
  小林栄治
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor therapeutics
- Research Institution
  University of Toyama
Challenge the infectious diseases and cancers using innovative array technology: Development of hTEC10
- Principal Investigator
  
  MURAGUCHI Atsushi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Infectious disease medicine
- Research Institution
  University of Toyama
Detection of cancer specific T cells on a chip
- Principal Investigator
  
  KISHI HIROYUKI
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor immunology
- Research Institution
  University of Toyama
Development of therapeutic hepatitis peptide vaccine using a novel T cell receptor cloning systemPrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Eiji
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Infectious disease medicine
- Research Institution
  University of Toyama

[Journal Article] Development of a Novel CD26-Targeted Chimeric Antigen Receptor T-Cell Therapy for CD26-Expressing T-Cell Malignancies2023
- Author(s)
  Kobayashi Eiji、Kamihara Yusuke、Arai Miho、Wada Akinori、Kikuchi Shohei、Hatano Ryo、Iwao Noriaki、Susukida Takeshi、Ozawa Tatsuhiko、Adachi Yuichi、Kishi Hiroyuki、Dang Nam H.、Yamada Taketo、Hayakawa Yoshihiro、Morimoto Chikao、Sato Tsutomu
- Journal Title
  
  Cells
  
  Volume: 12 Issue: 16 Pages: 2059-2059
- DOI
  10.3390/cells12162059
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06501, KAKENHI-PROJECT-22K19387, KAKENHI-PROJECT-21H02782, KAKENHI-PROJECT-23K27395
[Journal Article] Selection of highly responsive T cell receptors by an analysis combining the expression of multiple markers2023
- Author(s)
  My Thi Viet Ha, Hiroshi Hamana, Kiyomi Shitaoka, Abdul Hayee, Eiji Kobayashi, Toshiaki Yoshikawa, Tetsuya Nakatsura, Reiko Saikawa, Eri Sato, Mitsujiro Osawa, Yasumichi Hitoshi, Tung Son Dang, Tatsuhiko Ozawa, Hiroyuki Kishi
- Journal Title
  
  Cancer Science
  
  Volume: - Issue: 6 Pages: 2254-2264
- DOI
  10.1111/cas.15776
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16372, KAKENHI-PROJECT-21H02782, KAKENHI-PROJECT-21K18261, KAKENHI-PROJECT-21H02962, KAKENHI-PROJECT-23K27423
[Journal Article] DPP8 Selective Inhibitor Tominostat as a Novel and Broad-Spectrum Anticancer Agent against Hematological Malignancies2023
- Author(s)
  Kikuchi S, Wada A, Kamihara Y, Okazaki K, Jawaid P, Rehman MU, Kobayashi E, Susukida T, Minemura T, Nabe Y, Iwao N, Ozawa T, Hatano R, Yamada M, Kishi H, Matsuya Y, Mizuguchi M, Hayakawa Y, Dang NH, Sakamoto Y, Morimoto C, Sato T
- Journal Title
  
  Cells
  
  Volume: 12 Issue: 7 Pages: 1100-1100
- DOI
  10.3390/cells12071100
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K18261, KAKENHI-PROJECT-23K06501, KAKENHI-PROJECT-21K07237, KAKENHI-PROJECT-21H02782, KAKENHI-PROJECT-23K27395, KAKENHI-PROJECT-23K27423
[Journal Article] Gene modified NK cell line as a powerful tool for evaluation of cloned TCRs for TCR-T cell therapy2023
- Author(s)
  Kobayashi Eiji、Ozawa Tatsuhiko、Hamana Hiroshi、Muraguchi Atsushi、Kishi Hiroyuki
- Journal Title
  
  Cellular Immunology
  
  Volume: 383 Pages: 104656-104656
- DOI
  10.1016/j.cellimm.2022.104656
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02782, KAKENHI-PROJECT-21H02962, KAKENHI-PROJECT-21K18261, KAKENHI-PROJECT-23K27423
[Journal Article] N-glycan in the variable region of monoclonal ACPA (CCP-Ab1) promotes the exacerbation of experimental arthritis2023
- Author(s)
  Kawataka Masatoshi、Ouhara Kazuhisa、Kobayashi Eiji、Shinoda Koichiro、Tobe Kazuyuki、Fujimori Ryousuke、Mizuno Noriyoshi、Sugiyama Eiji、Ozawa Tatsuhiko、Kishi Hiroyuki
- Journal Title
  
  Rheumatology
  
  Volume: - Issue: 12 Pages: 3968-3977
- DOI
  10.1093/rheumatology/kead130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K09983, KAKENHI-PROJECT-21H02782, KAKENHI-PROJECT-21K18261, KAKENHI-PROJECT-21H02962, KAKENHI-PROJECT-23K27423
[Journal Article] Rapid cloning of antigen-specific T-cell receptors by leveraging the cis activation of T cells2022
- Author(s)
  Kobayashi E, Jin A, Hamana H, Shitaoka K, Tajiri K, Kusano S, Yokoyama S, Ozawa T, Obata T, Muraguchi A, Kishi H
- Journal Title
  
  Nat Biomed Eng
  
  Volume: 6 Issue: 7 Pages: 806-818
- DOI
  10.1038/s41551-022-00874-6
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K18261, KAKENHI-PROJECT-21H02782, KAKENHI-PROJECT-21H02962, KAKENHI-PROJECT-21H02966
[Journal Article] Evaluation of chimeric antigen receptor of humanized rabbit‐derived T cell receptor‐like antibody2022
- Author(s)
  Nakamura Tomoko、Kobayashi Eiji、Hamana Hiroshi、Hayakawa Yoshihiro、Muraguchi Atsushi、Hayashi Atsushi、Ozawa Tatsuhiko、Kishi Hiroyuki
- Journal Title
  
  Cancer Science
  
  Volume: 113 Issue: 10 Pages: 3321-3329
- DOI
  10.1111/cas.15478
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02782, KAKENHI-PROJECT-21H02962, KAKENHI-PROJECT-21H02966
[Journal Article] TCR function analysis using a novel system reveals the multiple unconventional tumor‐reactive T cells in human breast cancer‐infiltrating lymphocytes2021
- Author(s)
  Yamaguchi Satoshi、Hamana Hiroshi、Shitaoka Kiyomi、Sukegawa Kenta、Nagata Takuya、Hayee Abdul、Kobayashi Eiji、Ozawa Tatsuhiko、Fujii Tsutomu、Muraguchi Atsushi、Tobe Kazuyuki、Kishi Hiroyuki
- Journal Title
  
  European Journal of Immunology
  
  Volume: 51 Issue: 9 Pages: 2306-2316
- DOI
  10.1002/eji.202049070
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03730, KAKENHI-PROJECT-21H02782, KAKENHI-PROJECT-21H02962, KAKENHI-PROJECT-21H02966, KAKENHI-PROJECT-21K18261
[Journal Article] Rapid and efficient generation of T-cell receptor-like antibodies using chip-based single-cell analysis.2021
- Author(s)
  Ozawa T, Kobayashi E, Hamana H, Nakamura T, Lyu F, Hayashi A, Muraguchi A, Kishi H
- Journal Title
  
  Eur. J. Immunol.
  
  Volume: in press Issue: 7 Pages: 1850-1853
- DOI
  10.1002/eji.202049083
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06499, KAKENHI-PROJECT-18H02689, KAKENHI-PROJECT-21H02782, KAKENHI-PROJECT-21H02962, KAKENHI-PROJECT-21H02966, KAKENHI-PROJECT-21H02971
[Journal Article] Analysis of TCR repertoire and PD-1 expression in decidual and peripheral CD8+ T cells reveals distinct immune mechanisms in miscarriage and preeclampsia.2020
- Author(s)
  Morita K, Tsuda S, Kobayashi E, Hamana H, Tsuda K, Shima T, Nakashima A, Ushijima A, Kishi H, Saito S.
- Journal Title
  
  Front Immunol.
  
  Volume: 11 Pages: 1082-1082
- DOI
  10.3389/fimmu.2020.01082
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09750, KAKENHI-PLANNED-16H06499, KAKENHI-PROJECT-18K07321, KAKENHI-PROJECT-19K18690
[Journal Article] Relationship between T cell receptor clonotype and PD-1 expression of tumor-infiltrating lymphocytes in colorectal cancer.2020
- Author(s)
  Sukegawa K, Shitaoka K, Hamana H, Kobayashi E, Miyahara Y, Fujii K, Tsuda K, Saeki S, Nagata T, Ozawa T, Saito S, Fujii T, Muraguchi A, Shiku H, Kishi H.
- Journal Title
  
  Eur. J. Immunol.
  
  Volume: 50 Issue: 10 Pages: 1580-1590
- DOI
  10.1002/eji.201948399
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06499, KAKENHI-PROJECT-18H02689, KAKENHI-PROJECT-18K07321, KAKENHI-PROJECT-18K16301
[Journal Article] A novel and simple method to produce large amounts of recombinant soluble peptide/major histocompatibility complex monomers for analysis of antigen-specific human T cell receptors2019
- Author(s)
  Lyu Fulian、Ozawa Tatsuhiko、Hamana Hiroshi、Kobayashi Eiji、Muraguchi Atsushi、Kishi Hiroyuki
- Journal Title
  
  New Biotechnology
  
  Volume: 49 Pages: 169-177
- DOI
  10.1016/j.nbt.2018.11.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19441, KAKENHI-PLANNED-16H06499, KAKENHI-PROJECT-17H04219, KAKENHI-PROJECT-18H02689
[Journal Article] Identification of Tumoricidal TCRs from Tumor-Infiltrating Lymphocytes by Single-Cell Analysis2018
- Author(s)
  Shitaoka Kiyomi、Hamana Hiroshi、Kishi Hiroyuki、Hayakawa Yoshihiro、Kobayashi Eiji、Sukegawa Kenta、Piao Xiuhong、Lyu Fulian、Nagata Takuya、Sugiyama Daisuke、Nishikawa Hiroyoshi、Tanemura Atsushi、Katayama Ichiro、Murahashi Mutsunori、Takamatsu Yasushi、Tani Kenzaburo、Ozawa Tatsuhiko、Muraguchi Atsushi
- Journal Title
  
  Cancer Immunology Research
  
  Volume: 6 Issue: 4 Pages: 378-388
- DOI
  10.1158/2326-6066.cir-17-0489
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-16H06499, KAKENHI-PROJECT-15H04308, KAKENHI-PROJECT-15K09522, KAKENHI-PROJECT-18K19441, KAKENHI-PROJECT-17H01547, KAKENHI-PROJECT-15H04980, KAKENHI-PROJECT-17H04219, KAKENHI-PROJECT-17H06162, KAKENHI-PROJECT-17K09464
[Journal Article] Association Between High-Avidity T-Cell Receptors, Induced by α-Fetoprotein-Derived Peptides, and Anti-Tumor Effects in Patients With Hepatocellular Carcinoma2017
- Author(s)
  Nakagawa H, Mizukoshi E, Kobayashi E, Tamai T, Hamana H, Ozawa T, Kishi H, Kitahara M, Yamashita T, Arai K, Terashima T, Iida N, Fushimi K, Muraguchi A, Kaneko S
- Journal Title
  
  Gastroenterology
  
  Volume: 152 Issue: 6 Pages: 1395-1406
- DOI
  10.1053/j.gastro.2017.02.001
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06499, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-26293237, KAKENHI-PROJECT-16K15425, KAKENHI-PROJECT-15H04980, KAKENHI-PROJECT-15K09522
[Journal Article] Mechanosensing drives acuity ofαβT-cell recognition2017
- Author(s)
  Feng Yinnian、Brazin Kristine N.、Kobayashi Eiji、Mallis Robert J.、Reinherz Ellis L.、Lang Matthew J.
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 114 Issue: 39
- DOI
  10.1073/pnas.1703559114
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04219
[Journal Article] Immunological features of T cells induced by human telomerase reverse transcriptase-derived peptides in patients with hepatocellular carcinoma.2015
- Author(s)
  E Mizukoshi, H Nakagawa, M Kitahara, T Yamashita, K Arai, H Sunagozaka, K Fushimi, E Kobayashi, H Kishi, A Muraguchi, S Kaneko.
- Journal Title
  
  Cancer Lett
  
  Volume: 364 Issue: 2 Pages: 98-105
- DOI
  10.1016/j.canlet.2015.04.031
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-15H04308, KAKENHI-PROJECT-15H04980, KAKENHI-PROJECT-25460984, KAKENHI-PROJECT-25670463, KAKENHI-PROJECT-26293237
[Journal Article] Monoclonal Antibody Against Citrullinated Peptides Obtained From Rheumatoid Arthritis Patients Reacts With Numerous Citrullinated Microbial and Food Proteins2015
- Author(s)
  Reina Tsuda, Tatsuhiko Ozawa, Eiji Kobayashi, Hiroshi Hamana, Hirofumi Taki, Kazuyuki Tobe, Eiji Sugiyama, Masahiro Iwamoto, Johji Imura, Hiroyuki Kishi, Atsushi Muraguchi
- Journal Title
  
  Arthritis & Rheumatology
  
  Volume: 67 Issue: 8 Pages: 2020-2031
- DOI
  10.1002/art.39161
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K09522, KAKENHI-PROJECT-15H04980, KAKENHI-PROJECT-25670463, KAKENHI-PROJECT-26293237
[Journal Article] A novel system for cloning human TCRs : Cutting short the way to TCR-based anticancer therapy2014
- Author(s)
  Kobayashi E, Kishi H, Muraguchi A
- Journal Title
  
  Oncoimmunology
  
  Volume: 3(1)
- URL
  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960297/
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791019
[Journal Article] A novel system for cloning human TCRs : Cutting short the way to TCR-based anticancer therapy2014
- Author(s)
  Kobayashi E, Kishi H, Muraguchi A
- Journal Title
  
  Oncoimmunology
  
  Volume: 3 Issue: 1 Pages: e27258-e27258
- DOI
  10.4161/onci.27258
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390264, KAKENHI-PROJECT-24650630
[Journal Article] Retroviral vectors for homologous recombination provide efficient cloning and expression in mammalian cells2014
- Author(s)
  Kobayashi E, Kishi H, Ozawa T, Horii M, Hamana H, Nagai T, Muraguchi A
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 444 Issue: 3 Pages: 319-324
- DOI
  10.1016/j.bbrc.2014.01.049
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390264, KAKENHI-PROJECT-24650630, KAKENHI-PROJECT-24791019, KAKENHI-PUBLICLY-25133703, KAKENHI-PROJECT-25670463
[Journal Article] A chimeric antigen receptor for TRAIL-receptor 1 induces apoptosis in various types of tumor cells.2014
- Author(s)
  Kobayashi E, Kishi H, Ozawa T, Hamana H, Nakagawa H, Jin A, Lin Z, Muraguchi A.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 453 Issue: 4 Pages: 798-803
- DOI
  10.1016/j.bbrc.2014.10.024
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-25133703, KAKENHI-PROJECT-25670463, KAKENHI-PROJECT-26293237
[Journal Article] A novel system for cloning human TCRs: Cutting short the way to TCR-based anticancer therapy.2014
- Author(s)
  Kobayashi E, Kishi H, Muraguchi A.
- Journal Title
  
  Oncoimmunology
  
  Volume: 3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670463
[Journal Article] A novel system for cloning human TCRs: Cutting short the way to TCR-based anticancer therapy.2014
- Author(s)
  Kobayashi E, Kishi H, Muraguchi A
- Journal Title
  
  OncoImmunology
  
  Volume: 2
- Data Source
  KAKENHI-PROJECT-24650630
[Journal Article] A new cloning and expression system yields and validates TCRs from blood lymphocytes of patients with cancer within 10 days.2013
- Author(s)
  Kobayashi E., et al
- Journal Title
  
  Nature Medicne
  
  Volume: 19 Issue: 11 Pages: 1542-1546
- DOI
  10.1038/nm.3358
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11F01415, KAKENHI-PROJECT-23390264, KAKENHI-PROJECT-24650630, KAKENHI-PROJECT-24791019, KAKENHI-PUBLICLY-25133703, KAKENHI-PROJECT-25460984, KAKENHI-PROJECT-25670463
[Journal Article] The binding affinity of a soluble TCR-Fc fusion protein is significantly improved by crosslinkage with an anti-Cβ antibody2012
- Author(s)
  Ozawa T ., Horii M., Kobayashi E., Jin A., Kishi H., and Muraguchi A
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 422 Issue: 2 Pages: 245-249
- DOI
  10.1016/j.bbrc.2012.04.134
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390264, KAKENHI-PROJECT-23790617, KAKENHI-PROJECT-24650630, KAKENHI-PROJECT-24791019
[Journal Article] A novel rabbit immunospot array assay on a chip allows for the rapid generation of rabbit monoclonal antibodies with high affinity.2012
- Author(s)
  Ozawa T., et al
- Journal Title
  
  PLoS One
  
  Volume: 7 Issue: 12 Pages: e52383-e52383
- DOI
  10.1371/journal.pone.0052383
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11F01415, KAKENHI-PROJECT-23390264, KAKENHI-PROJECT-23790617, KAKENHI-PROJECT-24650630, KAKENHI-PROJECT-24791019
[Patent] 抗原特異的T細胞受容体の取得方法2014
- Inventor(s)
  小林栄治,岸裕幸,村口篤
- Industrial Property Rights Holder
  国立大学法人富山大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-007576
- Filing Date
  2014-01-20
- Data Source
  KAKENHI-PROJECT-24650630
[Patent] 抗原特異的T細胞受容体の取得方法2014
- Inventor(s)
  小林栄治, 岸裕幸, 村口篤
- Industrial Property Rights Holder
  国立大学法人富山大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-007576
- Filing Date
  2014-01-20
- Data Source
  KAKENHI-PROJECT-24791019
[Patent] 外来遺伝子導入用ベクター及び外来遺伝子が導入されたベクターの製造方法2013
- Inventor(s)
  堀井雅恵, 岸裕幸, 小林栄治, 小澤龍彦, 村口篤
- Industrial Property Rights Holder
  国立大学法人富山大学
- Industrial Property Rights Type
  特許
- Acquisition Date
  2013-04-19
- Data Source
  KAKENHI-PROJECT-24791019
[Patent] T細胞受容体のクローニング方法2013
- Inventor(s)
  村口篤,岸裕幸,小林栄治,小澤龍彦
- Industrial Property Rights Holder
  国立大学法人富山大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2012-016444
- Filing Date
  2013-07-25
- Data Source
  KAKENHI-PROJECT-24650630
[Patent] 外来遺伝子導入用ベクター及び外来遺伝子が導入されたベクターの製造方法2013
- Inventor(s)
  堀井雅恵,岸裕幸,小林栄治,小澤龍彦,村口篤
- Industrial Property Rights Holder
  国立大学法人富山大学
- Industrial Property Rights Type
  特許
- Acquisition Date
  2013-04-19
- Data Source
  KAKENHI-PROJECT-24650630
[Patent] T細胞の刺激方法およびその利用2013
- Inventor(s)
  岸裕幸,村口篤,浜名洋,小林栄治,小澤龍彦
- Industrial Property Rights Holder
  国立大学法人富山大学
- Industrial Property Rights Type
  特許
- Filing Date
  2013-03-06
- Overseas
- Data Source
  KAKENHI-PROJECT-24650630
[Patent] T細胞の刺激方法およびその利用2013
- Inventor(s)
  岸裕幸, 村口篤, 浜名洋, 小林栄治, 小澤龍彦
- Industrial Property Rights Holder
  国立大学法人富山大学
- Industrial Property Rights Type
  特許
- Filing Date
  2013-03-06
- Overseas
- Data Source
  KAKENHI-PROJECT-24791019
[Patent] T細胞受容体のクローニング方法2013
- Inventor(s)
  村口篤,岸裕幸,小林栄治,小澤龍彦
- Industrial Property Rights Holder
  国立大学法人富山大学
- Industrial Property Rights Type
  特許
- Filing Date
  2013-07-24
- Overseas
- Data Source
  KAKENHI-PROJECT-24650630
[Patent] T細胞受容体のクローニング方法2013
- Inventor(s)
  村口篤, 岸裕幸, 小林栄治, 小澤龍彦
- Industrial Property Rights Holder
  国立大学法人富山大学
- Industrial Property Rights Type
  特許
- Filing Date
  2013-07-24
- Overseas
- Data Source
  KAKENHI-PROJECT-24791019
[Patent] T細胞受容体のクローニング方法2012
- Inventor(s)
  村口篤, 岸裕幸, 小林栄治, 小澤龍彦
- Industrial Property Rights Holder
  国立大学法人富山大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2012-164442
- Filing Date
  2012-07-25
- Data Source
  KAKENHI-PROJECT-24791019
[Presentation] Development of a NK cell line to evaluate cytotoxicity of cloned TCRs2024
- Author(s)
  KOBAYASHI Eiji, OZAWA Tatsuhiko, MURAGUCHI Atsushi and KISHI Hiroyuki
- Organizer
  第52回日本免疫学会
- Data Source
  KAKENHI-PROJECT-21H02782
[Presentation] Evaluation of tumor infiltrating lymphocytes (TILs)-derived MR1 restricted TCRs of breast cancer patients2024
- Author(s)
  Abdul Hayee, Eiji Kobayashi, Hiroshi Hamana, Satoshi Yamaguchi, Ha Thi Viet My, Tatsuhiko Ozawa, Hiroyuki Kishi
- Organizer
  第52回日本免疫学会
- Data Source
  KAKENHI-PROJECT-21H02782
[Presentation] Comprehensive analysis of MR1-restricted TCR derived from infiltrating lymphocytes of breast cancer patients2023
- Author(s)
  Abdul Hayee, Eiji Kobayashi, Hiroshi Hamana, Satoshi Yamaguchi, Ha Thi Viet My, Tatsuhiko Ozawa, Hiroyuki Kishi
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K27423
[Presentation] Comprehensive analysis of MR1-restricted TCR derived from infiltrating lymphocytes of breast cancer patients2023
- Author(s)
  Abdul Hayee, Eiji Kobayashi, Hiroshi Hamana, Satoshi Yamaguchi, Ha Thi Viet My, Tatsuhiko Ozawa, Hiroyuki Kishi
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21H02782
[Presentation] T細胞リンパ腫・白血病のCD26を標的とした第3世代CAR-T細胞療法の開発2023
- Author(s)
  神原悠輔、小林栄治、洞口龍介、藤平琢磨、峯村友樹、奈邊愛美、菊地尚平、和田暁法、波多野良、岸　裕幸、森本幾夫、佐藤　勉
- Organizer
  第８５回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-23K27423
[Presentation] T細胞リンパ腫・白血病のCD26を標的とした第3世代CAR-T細胞療法の開発2023
- Author(s)
  神原悠輔、小林栄治、洞口龍介、藤平琢磨、峯村友樹、奈邊愛美、菊地尚平、和田暁法、波多野良、岸　裕幸、森本幾夫、佐藤　勉
- Organizer
  第85回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-21H02782
[Presentation] Rapid cloning of antigen-specific T-cell receptors by applying T cell cisactivation.2022
- Author(s)
  Kobayashi E, Ozawa T, Tajiri K, Kusano S, Yokoyama S, Muraugchi A, Kishi H.
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-21H02966
[Presentation] T-ISAAC法によるがん特異的TCRの同定2022
- Author(s)
  小林栄治, 下岡清美, 横山茂之, 岸裕幸
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21H02782
[Presentation] Selection of high avidity TCRs based on the expression of marker on BW cells2022
- Author(s)
  My H, Hamana H, Kobayashi E, Ozawa T, Hayee A, Kishi H
- Organizer
  第26回日本癌免疫学会総会
- Data Source
  KAKENHI-PROJECT-21H02966
[Presentation] Selection of highly responsive TCRs by analysis combining the expression of multiple markers on BW5147.3 T cells2022
- Author(s)
  My H, Hamana H, Kobayashi E, Ozawa T, Dang S, Hayee A, Kishi H
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-21H02966
[Presentation] Detection of HLAindependent T cell receptors derived from tumor infiltrating lymphocytes of breast cancer patients2022
- Author(s)
  Hayee A, Yamaguchi A, Hamana H, Shitaoka K, Kobayashi E, Ozawa T, My H, Muraguchi A, Kishi H.
- Organizer
  第26回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-21H02782
[Presentation] Analysis of HLA- class-I unrestricted T cell receptors obtained from tumor infiltrating lymphocytes of breast cancer patients2022
- Author(s)
  Hayee A, Yamaguchi S, Hamana H, Shitaoka K, Kobayashi E, Ozawa T, My H, Muraguchi A, Kishi H
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-21H02966
[Presentation] Rapid cloning of antigen-specific T-cell receptors by applying T cell cis-activation2022
- Author(s)
  Kobayashi E, Ozawa T, Tajiri K, Kusano S, Yokoyama S, Muraugchi A, Kishi H.
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-21H02782
[Presentation] Analysis of HLAclass- I unrestricted T cell receptors obtained from tumor infiltrating lymphocytes of breast cancer patients2022
- Author(s)
  Hayee A, Yamaguchi S, Hamana H, Shitaoka K, Kobayashi E, Ozawa T, My H, Muraguchi A, Kishi H.
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-21H02782
[Presentation] Selection of highly responsive TCRs by analysis combining the expression of multiple markers on BW5147.3 T cells2022
- Author(s)
  My H, Hamana H, Kobayashi E, Ozawa T, Dang S, Hayee A, Kishi H.
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-21H02782
[Presentation] Selection of high avidity TCRs based on the expression of marker on BW cells2022
- Author(s)
  My H, Hamana H, Kobayashi E, Ozawa T, Hayee A, Kishi H.
- Organizer
  第26回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-21H02782
[Presentation] T-ISAAC法によるがん特異的TCRの同定2022
- Author(s)
  小林栄治、下岡清美、横山茂之、岸裕幸
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21H02966
[Presentation] ISAAC法を用いたTCR様抗体の効率的な取得法の開発とがん免疫療法への応用2021
- Author(s)
  小澤龍彦, 中村友子, 小林栄治, 浜名　洋, 林　篤志, 村口　篤, 岸　裕幸
- Organizer
  第21回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-21H02782
[Presentation] 内在性抗原反応性TCRの網羅的スクリーニング法の開発および乳癌浸潤T細胞解析への応用.2021
- Author(s)
  山口智史, 浜名　洋, 小林栄治, 小澤龍彦, 村口　篤, 戸邉一之, 岸　裕幸.
- Organizer
  第25回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-21H02966
[Presentation] Characterization of HLA class I-unrestricted T cells found in tumor infiltrating lymphocytes of breast cancer patients2021
- Author(s)
  Abdul Hayee, Yamaguchi S, Hamana H, Shitaoka K, Kobayashi E, Ozawa T, Muraguchi A, Kishi H.
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21H02782
[Presentation] Humanization of rabbit-derived T cell receptor-like antibodies and their evaluation.2021
- Author(s)
  Nakamura T, Ozawa T, Kobayashi E, Hamana H, Muraguchi A, Kishi H.
- Organizer
  第50回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-21H02966
[Presentation] Identification of tumor antigen-specific TCRs using immunospot array assay on a chip(T-ISAAC) technology.2021
- Author(s)
  Kobayashi E, Ozawa T, Hamana H, Muraguchi A, Kishi H.
- Organizer
  第50回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-21H02966
[Presentation] Screening of neoantigen-specific TCRs using TAP fragment and Jurkat cells.2021
- Author(s)
  Hamana H, Miyahara Y, Kobayashi E, Ozawa T, Muraguchi A, Shiku H, Kishi H.
- Organizer
  第50回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-21H02966
[Presentation] Screening of neoantigen-specific TCRs using TAP fragment and Jurkat cells.2021
- Author(s)
  Hamana H, Miyahara Y, Kobayashi E, Ozawa T, Muraguchi A, Shiku H, Kishi H.
- Organizer
  第50回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-21H02782
[Presentation] Comprehensive TCR-function analysis in TILs of breast cancer revealed multiple tumor-reactive MR1-restricted TCRs2021
- Author(s)
  Kishi H, Yamaguchi S, Hamana H, Shitaoka K, Nagata T, Kobayashi E, Ozawa T, Muraguchi A.
- Organizer
  第50回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-21H02782
[Presentation] Comprehensive TCR-function analysis in TILs of breast cancer revealed multiple tumor-reactive MR1-restricted TCRs.2021
- Author(s)
  Kishi H, Yamaguchi S, Hamana H, Shitaoka K, Nagata T, Kobayashi E, Ozawa T, Muraguchi A.
- Organizer
  第50回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-21H02966
[Presentation] 汎用培養細胞株を用いたネオアンチゲン特異的TCRのクローニング2021
- Author(s)
  浜名　洋, 宮原慶裕, 小林栄治, 小澤龍彦, 村口　篤, 珠玖　洋, 岸　裕幸
- Organizer
  第25回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-21H02782
[Presentation] Characterization of HLA class I-unrestricted T cells found in tumor infiltrating lymphocytes of breast cancer patients.2021
- Author(s)
  Abdul Hayee, Yamaguchi S, Hamana H, Shitaoka K, Kobayashi E, Ozawa T, Muraguchi A, Kishi H.
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21H02966
[Presentation] Identification of tumor antigen-specific TCRs using immunospot array assay on a chip(T-ISAAC) technology2021
- Author(s)
  Kobayashi E, Ozawa T, Hamana H, Muraguchi A, Kishi H
- Organizer
  第50回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-21H02782
[Presentation] ISAAC法を用いたTCR様抗体の効率的な取得法の開発とがん免疫療法への応用.2021
- Author(s)
  小澤龍彦, 中村友子, 小林栄治, 浜名　洋, 林　篤, 村口　篤, 岸　裕幸.
- Organizer
  第21回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-21H02966
[Presentation] 汎用培養細胞株を用いたネオアンチゲン特異的TCRのクローニング.2021
- Author(s)
  浜名　洋, 宮原慶裕, 小林栄治, 小澤龍彦, 村口　篤, 珠玖　洋, 岸　裕幸.
- Organizer
  第25回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-21H02966
[Presentation] Humanization of rabbit-derived T cell receptor-like antibodies and their evaluation2021
- Author(s)
  Nakamura T, Ozawa T, Kobayashi E, Hamana H, Muraguchi A, Kishi H
- Organizer
  第50回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-21H02782
[Presentation] 正常妊娠と異常妊娠における脱落膜CD8+T細胞のTCRレパートリーとPD-1の発現についての検討2020
- Author(s)
  森田恵子，津田さやか，小林栄治，浜名　洋，津田　桂，島　友子，中島彰俊，岸　裕幸，齋藤　滋
- Organizer
  第28回日本胎盤学会学術集会
- Data Source
  KAKENHI-PROJECT-18K07321
[Presentation] 大腸がん浸潤リンパ球におけるTCRクロノタイプとPD-1の発現2020
- Author(s)
  岸　裕幸，下岡清美，小林栄治，宮原慶裕，津田　桂，佐伯しおり，長田拓哉，村口　篤，珠玖　洋
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K07321
[Presentation] Development of a novel tumor antigen-specific TCR cloning system using a microarray chip2020
- Author(s)
  KOBAYASHI Eiji, OZAWA Tatsuhiko, HAMANA hiroshi, MURAGUCHI Atsushi, KISHI Hiroyuki
- Organizer
  第24回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-18K07321
[Presentation] ISAAC法を用いたTCR様抗体の迅速作製とその応用2020
- Author(s)
  小澤龍彦，小林栄治，浜名　洋，村口　篤，岸　裕幸
- Organizer
  第24回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-18K07321
[Presentation] Jurkat細胞を用いたTCRのネオアンチゲン反応性解析2020
- Author(s)
  小澤龍彦，小林栄治，浜名　洋，村口　篤，岸　裕幸
- Organizer
  第28回日本胎盤学会学術集会
- Data Source
  KAKENHI-PROJECT-18K07321
[Presentation] Screening of tumor-reactive TCRs from TILs of breast cancer patients using a patients' HLA-transduced breast cancer cell line.2019
- Author(s)
  Hamana H, Shitaoka K, Sukegawa K, Saeki S, Nagata T, Kobayashi E, Ozawa T, Fujii T, Muraguchi A, Kishi H
- Organizer
  第49回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-18K07321
[Presentation] 腫瘍浸潤CD8+ T細胞におけるPD-1の発現はTCRレパトアに規定される2019
- Author(s)
  祐川　健太，佐伯しおり，下岡　清美，浜名　洋，宮原　慶裕，小林　栄治，長田任一哉，小澤　龍彦，藤井　努，珠玖　洋，村口　篤，岸　裕幸
- Organizer
  第23回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-18K07321
[Presentation] Clonally expanded populations of cytotoxic T cell in TILs and peripheral blood in endometrial cancer patients2019
- Author(s)
  津田　桂，浜名　洋，中島　彰俊，森田　恵子，津田さやか，島　友子，下岡　清美，小林　栄治，小澤　龍彦，村口　篤，岸　裕幸
- Organizer
  第23回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-18K07321
[Presentation] 患者HLA遺伝子導入乳がん細胞株を用いた乳がん患者TIL中の腫瘍反応性TCRの探索2019
- Author(s)
  浜名　洋，下岡　清美，祐川　健太，佐伯しおり，長田任一哉，小林　栄治，小澤　龍彦，藤井　努，村口　篤，岸　裕幸
- Organizer
  第23回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-18K07321
[Presentation] A novel TCR cloning system of peptide-specific T cells using immunospot array assay on a chip(T-ISAAC) technology.2019
- Author(s)
  Kobayashi E, Ozawa T, Hamana H, Shitaoka K, Muraguchi A, Kishi H.
- Organizer
  International Conference on Lymphocyte Engineering 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04219
[Presentation] Cloning of tumor antigen-specific TCRs using immunospot array assay on a chip (T-ISAAC) technology.2019
- Author(s)
  Kobayashi E, Ozawa T, Hamana H, Shitaoka K, Muraguchi A, Kishi H.
- Organizer
  第49回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04219
[Presentation] Common TCRβ repertoire was found in both decidual and peripheral CD8+ T cells in normal term pregnancy2019
- Author(s)
  Morita K, Kobayashi E, Tsuda S, Shitaoka K, Ozawa T, Hamana H, Saito S, Kishi H
- Organizer
  第49回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-18K07321
[Presentation] Clonally expanded populations of cytotoxic T cell in TILs and peripheral blood in endometrial cancer patients.2019
- Author(s)
  津田　桂，浜名　洋，中島　彰俊，森田　恵子，津田さやか，島　友子，下岡　清美，小林　栄治，小澤　龍彦，村口　篤，岸　裕幸．
- Organizer
  第23回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-17H04219
[Presentation] Screening of tumor-reactive TCRs from TILs of breast cancer patients using a patients' HLA-transduced breast cancer cell line.2019
- Author(s)
  Hamana H, Shitaoka K, Sukegawa K, Saeki S, Nagata T, Kobayashi E, Ozawa T, Fujii T, Muraguchi A, Kishi H.
- Organizer
  第49回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04219
[Presentation] 腫瘍浸潤CD8+ T細胞のTCRとPD-1の発現との関連：大腸癌における考察．2019
- Author(s)
  岸　裕幸，祐川　健太，下岡　清美，浜名　洋，小林　栄治，津田　桂，長田任一哉，佐伯しおり，小澤　龍彦，齋藤　滋，藤井　努，村口　篤
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K07321
[Presentation] 腫瘍浸潤CD8+ T細胞のTCRとPD-1の発現との関連：大腸癌における考察．2019
- Author(s)
  岸　裕幸，祐川　健太，下岡　清美，浜名　洋，小林　栄治，津田　桂，長田任一哉，佐伯しおり，小澤　龍彦，齋藤　滋，藤井　努，村口　篤．
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17H04219
[Presentation] Cloning of tumor antigen-specific TCRs using immunospot array assay on a chip (T-ISAAC) technology2019
- Author(s)
  Kobayashi E, Ozawa T, Hamana H, Shitaoka K, Muraguchi A, Kishi H
- Organizer
  第49回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-18K07321
[Presentation] 患者HLA遺伝子導入乳がん細胞株を用いた乳がん患者TIL中の腫瘍反応性TCRの探索．2019
- Author(s)
  浜名　洋，下岡　清美，祐川　健太，佐伯しおり，長田任一哉，小林　栄治，小澤　龍彦，藤井　努，村口　篤，岸　裕幸．
- Organizer
  第23回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-17H04219
[Presentation] A novel TCR cloning system of peptide-specific T cells using immunospot array assay on a chip(T-ISAAC) technology2019
- Author(s)
  Kobayashi E, Ozawa T, Hamana H, Shitaoka K, Muraguchi A, Kishi H.
- Organizer
  International Conference on Lymphocyte Engineering 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07321
[Presentation] TCR repertoire analysis of cytotoxic T cells in tumor-infiltrated lymphocytes and peripheral blood lymphocytes in endometrial cancers2019
- Author(s)
  Tsuda K, Hamana H, Nakashima A, Tsuda S, Shima T, Shitaoka K, Kobayashi E, Ozawa T, Kishi H
- Organizer
  第49回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-18K07321
[Presentation] 腫瘍浸潤CD8+ T細胞におけるPD-1の発現はTCRレパトアに規定される．2019
- Author(s)
  祐川　健太，佐伯しおり，下岡　清美，浜名　洋，宮原　慶裕，小林　栄治，長田任一哉，小澤　龍彦，藤井　努，珠玖　洋，村口　篤，岸　裕幸．
- Organizer
  第23回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-17H04219
[Presentation] The development of antigen detection system using yeast surface display library.2018
- Author(s)
  Ohnuki Y, Ozawa T, Hamana H, Kobayashi E, Lyu F, Muraguchi A, Kishi H.
- Organizer
  第47回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04219
[Presentation] TCR repertoire analysis of peptide-specific T cells using immunospot array assay on a chip (T-ISAAC) technology2018
- Author(s)
  KOBAYASHI Eiji, OZAWA Tatsuhiko, HAMANA Hiroshi, SHITAOKA Kiyomi, MURAGUCHI Atsushi and KISHI Hiroyuki
- Organizer
  第47回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-18K07321
[Presentation] T-ISAAC法を用いたペプチド特異的T細胞のTCRレパトア解析．2018
- Author(s)
  小林栄治，村口　篤，岸　裕幸．
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17H04219
[Presentation] 酵母表面ディスプレイ法を用いたTCRの抗原ペプチド/MHCライブラリーの作製とそのスクリーニング．2018
- Author(s)
  小澤龍彦，大貫　燿，浜名　洋，小林栄治，呂　福蓮，村口　篤，岸　裕幸．
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H04219
[Presentation] 効率的な大腸癌免疫療法の確立に向けた腫瘍浸潤リンパ球レパートリー解析．2018
- Author(s)
  祐川健太，浜名　洋，下岡清美，小林栄治，北條荘三，奧村知之，長田拓哉，村口　篤，岸　裕幸，藤井　努．
- Organizer
  第29回日本消化器癌発生学会総会
- Data Source
  KAKENHI-PROJECT-17H04219
[Presentation] A rapid and simple protocol for cDNA cloning of tumor antigen-specific TCR.2018
- Author(s)
  Hamana H, Ozawa T, Kobayashi E, Shitaoka K, Muraguchi A, Kishi H.
- Organizer
  第47回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04219
[Presentation] Tumor infiltrating lymphocyte repertoire analysis of colon cancer.2018
- Author(s)
  Sukegawa K, Hamana H, Shitaoka K, Kobayashi E, Saeki S, Nagata T, Fujii T, Muraguchi A, Kishi H.
- Organizer
  第47回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04219
[Presentation] TCR repertoire analysis of peptide-specific T cells using immunospot array assay on a chip (T-ISAAC) technology.2018
- Author(s)
  Kobayashi E, Ozawa T, Hamana H, Shitaoka K, Muraguchi A, Kishi H.
- Organizer
  第47回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04219
[Presentation] TILでクローナルなT細胞受容体は，腫瘍に対して細胞障害性を示し，腫瘍関連抗原を認識する．2018
- Author(s)
  下岡清美，浜名　洋，小林栄治，早川芳弘，村口　篤，岸　裕幸．
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17H04219
[Presentation] Clonally expanded populations of cytotoxic T cell in tumor infiltrated lymphocyte and peripheral blood in uterine endometrial cancer.2018
- Author(s)
  Tsuda K, Kishi H, Nakashima A, Hamana H, Tsuda S, Shima T, Shitaoka K, Kobayashi E, Ozawa T, Muraguchi A, Saito S.
- Organizer
  第47回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04219
[Presentation] Development of TCR-antigen identification system using “cis-interaction” of TCR and peptide/MHC complex on a T cell.2018
- Author(s)
  Yamaguchi S, Kishi H, Shitaoka K, Hamana H, Kobayashi E, Ozawa T, Muraguchi A.
- Organizer
  第47回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04219
[Presentation] TCR repertoire analysis of peptide-specific T cells using immunospot array assay on a chip (T-ISAAC) technology2018
- Author(s)
  KOBAYASHI Eiji, MURAGUCHI Atsushi, KISHI Hiroyuki
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K07321
[Presentation] T cell receptor (TCR) gene cloning from tumor infiltrating lymphocytes of breast cancer patients toward TCR gene therapy.2017
- Author(s)
  Hamana H, Nagata T, Shitaoka K, Sukegawa K, Ozawa T, Kobayashi E, Muraguchi A, Kishi H.
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04219
[Presentation] A novel method to produce high amounts of recombinant MHC/peptide complexes for isolation of antigen-specific human TCRs.2017
- Author(s)
  Lyu F, Ozawa T, Hamana H, Kobayashi E, Muraguchi A, Kishi H.
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04219
[Presentation] 関節リウマチ患者由来自己抗体が認識する非変性状態の抗原の同定と自己抗体誘導仮説．2017
- Author(s)
  小澤龍彦，津田玲奈，浜名　洋，小林栄治，多喜博文，戸邉一之，村口　篤，岸　裕幸．
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-17H04219
[Presentation] Majority of tumor infiltrating lymphocytes in B16F10 melanoma recognized tumor-associated antigens, but not melanoma-associated antigens or neoantigens.2017
- Author(s)
  Shitaoka K, Hamana H, Kobayashi E, Ozawa T, Hayakawa Y, Muraguchi A, Kishi H.
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04219
[Presentation] 内皮細胞HLA-class II DRとアロ応答するCD4 T細胞は，anti-A/B抗体接着により抑制される．2017
- Author(s)
  岩﨑研太，三輪祐子，打田和治，堀見孔星，松岡　裕，岡田　学，浜名　洋，岸　裕幸，村口　篤，小林孝彰．
- Organizer
  第26回日本組織適合性学会大会
- Data Source
  KAKENHI-PROJECT-17H04219
[Presentation] The model of antigen detection system using yeast surface display library.2017
- Author(s)
  Ohnuki Y, Ozawa T, Hamana H, Kobayashi E, Lyu F, Muraguchi A, Kishi H.
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04219
[Presentation] Evolution of anti-citrullinated peptide antibody (ACPA): analysis of autoantigen under native condition using a human monoclonal ACPA.2017
- Author(s)
  Ozawa T, Tsuda R, Hamana H, Kobayashi E, Taki H, Muraguchi A, Kishi H.
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04219
[Presentation] TCR repertoire analysis of antigen-specific T cells using immunospot array assay on a chip (T-ISAAC) technology.2017
- Author(s)
  Kobayashi E, Ozawa T, Hamana H, Lyu F, Muraguchi A, Kishi H.
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04219
[Presentation] Cis-interaction of TCRs and antigen/MHC class I complexes on CD8+ T cells causes their activation.2016
- Author(s)
  Kishi H, Jin A, Hamana H, Shitaoka K, Tajiri K, Kobayashi E, Kusano S, Yokoyama S, Ozawa T, Nagai T, Obata T, Hatakeyama S, Horii M, Hu Y, Zhang F, Muraguchi A.
- Organizer
  2016 International Congress of Immunology
- Place of Presentation
  Melbourne（豪州）
- Year and Date
  2016-08-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293237
[Presentation] メラノーマ患者および健常人の末梢血CD4+ T細胞の単一細胞レベルでのレパートリー解析．2014
- Author(s)
  岸　裕幸，浜名　洋，小林栄治，杉山大介，西川博嘉，鬼塚志乃，坂口志文，村口　篤．
- Organizer
  第6回血液疾患免疫療法研究会学術集会
- Place of Presentation
  京都
- Year and Date
  2014-09-06
- Data Source
  KAKENHI-PROJECT-25670463
[Presentation] メラノーマ患者および健常人の末梢血CD4+ T細胞の単一細胞レベルでのレパートリー解析．2014
- Author(s)
  岸　裕幸，浜名　洋，小林栄治，杉山大介，西川博嘉，鬼塚志乃，坂口志文，村口　篤．
- Organizer
  第6回血液疾患免疫療法研究会学術集会
- Place of Presentation
  京都
- Year and Date
  2014-09-06
- Data Source
  KAKENHI-PROJECT-26293237
[Presentation] hTEC4 system that enable us to clone TCR cDNA from antigen specific single T cells with in 4 days.2013
- Author(s)
  Hamana H, Kobayashi E, Kishi H, Ozawa T, Nakagawa H, Jin A, Muraguchi A
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-24650630
[Presentation] Cis-interaction of TCR and antigenic peptides with MHC class I molecules on a CD8+ T-cell.2013
- Author(s)
  Kishi H, Jin A, Hamana H, Tajiri K, Kobayashi E, Ozawa T, Muraguchi A
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-24650630
[Presentation] Cloning and functional analysis of human telomerase reverse transcriptase (hTERT)-specific TCRs from peptide-vaccinated patients2013
- Author(s)
  Eiji Kobayashi, Hidetoshi Nakagawa, Hiroshi Hamana, Hiroyuki Kishi, Tatsuhiko Ozawa, Aishun Jin and Atsushi Muraguchi
- Organizer
  第42回日本免疫学会総会
- Place of Presentation
  幕張
- Year and Date
  2013-12-11
- Data Source
  KAKENHI-PROJECT-24791019
[Presentation] Rapid generation of rabbit monoclonal antibodies against phosphorylated peptides and G-protein coupled receptor.2013
- Author(s)
  Ozawa T, Piao X, Kobayashi E, Jin A, Kishi H, Muraguchi A.
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-25670463
[Presentation] Detection of antigen-stimulated cytokine-secretion in human T-cells at single cell levels on a live cell chip.2013
- Author(s)
  Kishi H, Jin A, Hamana H, Tajiri K, Hatakeyama S, Kobayashi E, Ozawa T, Nagai T, Muraguchi A
- Organizer
  15th International Congress of Immunology
- Place of Presentation
  Milan
- Data Source
  KAKENHI-PROJECT-24650630
[Presentation] Functional analysis of anti-cyclic citrullinated protein antibodies derived from rheumatoid arthritis.2013
- Author(s)
  Tsuda R, Ozawa T, Kobayashi E, Taki H, Kishi H, Muraguchi A.
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-25670463
[Presentation] 末梢血リンパ球中の抗原特異的CD8^+T細胞およびT細胞受容体の網羅的・迅速解析2013
- Author(s)
  岸裕幸,小林栄治,水腰英四郎,小澤龍彦,浜名洋,長井輝美,中河秀俊,金艾順,金子周一,村口篤
- Organizer
  第5回造血器腫瘍免疫療法研究会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2013-08-24
- Data Source
  KAKENHI-PROJECT-24650630
[Presentation] がん抗原特異的TCR遺伝子の迅速クローニング法2013
- Author(s)
  小林栄治，水腰英四郎，岸　裕幸，金子周一，村口　篤
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24650630
[Presentation] hTEC4 system that enable us to clone TCR cDNA from antigen specific single T cells with in 4 days.2013
- Author(s)
  Hamana H, Kobayashi E, Kishi H, Ozawa T, Nakagawa H, Jin A, Muraguchi A.
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-25670463
[Presentation] Cloning of human antigen-specific TCRs can confer the candidates for cancer gene therapy2013
- Author(s)
  Eiji Kobayashi, Eishiro Mizukoshi, Hiroyuki Kishi, Hiroshi Hamana, Terumi Nagai, Tatsuhiko Ozawa ,Hidetoshi Nakagawa, Aishun Jin, Shuichi Kaneko and Atsushi Muraguchi
- Organizer
  15th International Congress of Immunology
- Place of Presentation
  Miilan, Italy
- Data Source
  KAKENHI-PROJECT-24791019
[Presentation] リン酸化ペプチド及びGPCR特異的ウサギモノクローナル抗体の迅速作製法の開発．2013
- Author(s)
  13) 小澤龍彦，朴　秀虹，小林栄治，竹田浩之，澤崎達也，周　越，櫻井宏明，安東嗣修，金　艾順，岸　裕幸，村口　篤．
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25670463
[Presentation] A novel cloning system of human antigen-specific TCRs can confer the candidates for cancer gene therapy2013
- Author(s)
  Eiji Kobayashi, Eishiro Mizukoshi, Hiroyuki Kishi, Tatsuhiko Ozawa, Hiroshi Hamana, Terumi Nagai, Hidetoshi Nakagawa, Aishun Jin, Shuichi Kaneko and Atsushi Muraguchi
- Organizer
  第７２回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24791019
[Presentation] Construction of T cell antigen-exploring system.2013
- Author(s)
  Piao X, Hamana H, Kishi H, Kobayashi E, Ozawa T, Muraguchi A.
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-25670463
[Presentation] Cis-interaction of TCR and antigenic peptides with MHC class I molecules on a CD8+ T-cell.2013
- Author(s)
  Kishi H, Jin A, Hamana H, Tajiri K, Kobayashi E, Ozawa T, Muraguchi A.
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-25670463
[Presentation] Detection of antigen-stimulated cytokine-secretion in human T-cells at single cell levels on a live cell chip2013
- Author(s)
  Kishi H, Jin A, Hamana H, Tajiri K, Hatakeyama S, Kobayashi E, Ozawa T, Nagai T, Muraguchi A
- Organizer
  15^<th> International Congress of Immunology
- Place of Presentation
  Milan
- Data Source
  KAKENHI-PROJECT-24650630
[Presentation] Cloning of human antigen-specific TCRs can confer the candidates for cancer gene therapy.2013
- Author(s)
  Kobayashi E, Mizukoshi E, Kishi H, Hamana H, Nagai T, Ozawa T, Nakagawa H, Jin A, Kaneko S, Muraguchi A.
- Organizer
  15th International Congress of Immunology
- Place of Presentation
  Milan
- Data Source
  KAKENHI-PROJECT-25670463
[Presentation] Cis-interaction of TCR and antigenic peptides with MHC class I molecules on a CD8^+ T-cell2013
- Author(s)
  Kishi H, Jin A, Hamana H, Tajiri K, Kobayashi E, Ozawa T, Muraguchi A
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-24650630
[Presentation] 末梢血リンパ球中の抗原特異的CD8+T細胞およびT細胞受容体の網羅的・迅速解析．2013
- Author(s)
  岸　裕幸，小林栄治，水腰英四郎，小澤龍彦，浜名　洋，長井輝美，中河秀俊，金　艾順，金子周一，村口　篤．
- Organizer
  第5回造血器腫瘍免疫療法研究会学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-25670463
[Presentation] Detection of antigen-stimulated cytokine-secretion in human T-cells at single cell levels on a live cell chip2013
- Author(s)
  Kishi H, Jin A, Hamana H, Tajiri K, Hatakeyama S, Kobayashi E, Ozawa T, Nagai T, Muraguchi A
- Organizer
  Measuring Antigen-Specific Immune Responses (MASIR) 2013
- Place of Presentation
  Dubrovnik
- Data Source
  KAKENHI-PROJECT-24650630
[Presentation] A monoclonal CCP-antibody derived from RA patients binds to several citrullinated antigens in the human cellular components.2013
- Author(s)
  Ozawa T, Tuda R, Kobayashi E, Hounoki H, Shinoda K, Taki H, Tobe K, Kishi H, Muraguchi A.
- Organizer
  15th International Congress of Immunology
- Place of Presentation
  Milan
- Data Source
  KAKENHI-PROJECT-25670463
[Presentation] Detection of antigen-stimulated cytokine-secretion in human T-cells at single cell levels on a live cell chip.2013
- Author(s)
  Kishi H, Jin A, Hamana H, Tajiri K, Hatakeyama S, Kobayashi E, Ozawa T, Nagai T, Muraguchi A.
- Organizer
  Measuring Antigen-Specific Immune Responses (MASIR) 2013
- Place of Presentation
  Dubrovnik
- Data Source
  KAKENHI-PROJECT-25670463
[Presentation] Cloning and functional analysis of human telomerase reverse transcriptase (hTERT)-specific TCRs from peptide-vaccinated patients.2013
- Author(s)
  Kobayashi E, Nakagawa H, Hamana H, Kishi H, Ozawa T, Jin A, Muraguchi A.
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-25670463
[Presentation] Cloning of human antigen-specific TCRs can confer the candidates for cancer gene therapy2013
- Author(s)
  Eiji Kobayashi, Eishiro Mizukoshi, Hiroyuki Kishi, Hiroshi Hamana, Terumi Nagai, Tatsuhiko Ozawa , Hidetoshi Nakagawa, Aishun Jin, Shuichi Kaneko and Atsushi Muraguchi
- Organizer
  15th International Congress of Immunology
- Place of Presentation
  Milan
- Year and Date
  2013-08-22
- Data Source
  KAKENHI-PROJECT-24791019
[Presentation] Construction of T cell antigen-exploring system.2013
- Author(s)
  Piao X, Hamana H, Kishi H, Kobayashi E, Ozawa T, Muraguchi A
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-24650630
[Presentation] Detection of antigen-stimulated cytokine-secretion in human T-cells at single cell levels on a live cell chip.2013
- Author(s)
  Kishi H, Jin A, Hamana H, Tajiri K, Hatakeyama S, Kobayashi E, Ozawa T, Nagai T, Muraguchi A
- Organizer
  Measuring Antigen-Specific Immune Responses (MASIR) 2013
- Place of Presentation
  Dubrovnik
- Data Source
  KAKENHI-PROJECT-24650630
[Presentation] Cloning of human antigen-specific TCRs can confer the candidates for cancer gene therapy.2013
- Author(s)
  Kobayashi E, Mizukoshi E, Kishi H, Hamana H, Nagai T, Ozawa T, Nakagawa H, Jin A, Kaneko S, Muraguchi A
- Organizer
  15th International Congress of Immunology
- Place of Presentation
  Milan
- Data Source
  KAKENHI-PROJECT-24650630
[Presentation] A novel cloning system of human antigen-specific TCRs can confer the candidates for cancer gene therapy2013
- Author(s)
  E.kobayashi, Mizukoshi E., Kishi H., Hamana H., Nagai T., Ozawa T., Nakagawa H., Jin A., Kaneko S., and Muraguchi A
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2013-10-03
- Data Source
  KAKENHI-PROJECT-24791019
[Presentation] Cloning and functional analysis of human telomerase reverse transcriptase (hTERT)-specific TCRs from peptide-vaccinated patients.2013
- Author(s)
  Kobayashi E, Nakagawa H, Hamana H, Kishi H, Ozawa T, Jin A, Muraguchi A
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-24650630
[Presentation] Comparison of α-fetoprotein-specific TCR repertoires from hepatocellular carcinoma patients after peptide vaccine treatment and healthy donors.2013
- Author(s)
  Nakagawa H, Kobayashi E, Hamana H, Ozawa T, Kishi H, Muraguchi A.
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-25670463
[Presentation] がん抗原特異的TCR遺伝子の迅速クローニング法．2013
- Author(s)
  小林栄治，水腰英四郎，岸　裕幸，金子周一，村口　篤．
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25670463
[Presentation] Comparison of -fetoprotein-specific TCR repertoires from hepatocellular carcinoma patients after peptide vaccine treatment and healthy donors.2013
- Author(s)
  Nakagawa H*, Kobayashi E, Hamana H, Ozawa T, Kishi H, Muraguchi A
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-24650630
[Presentation] Comparison of TCR repertoires in EBV-specific T cells detected by three different staining methods2012
- Author(s)
  浜名洋, 小林栄治, 岸裕幸, 小澤龍彦, 金艾順, 村口篤
- Organizer
  第41回日本免疫学会学術集会
- Place of Presentation
  神戸
- Year and Date
  2012-12-05
- Data Source
  KAKENHI-PROJECT-24791019
[Presentation] がんのTCR遺伝子治療にむけた候補TCR遺伝子の迅速クローニング法2012
- Author(s)
  岸裕幸,小林栄治,水腰英四郎,小澤龍彦,金子周一,村口篤
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24650630
[Presentation] Detection of antigen-stimulated cytokine secretion in human T-cells at single cell levels on a live cell chip2012
- Author(s)
  岸裕幸,金艾順,小林栄治,小澤龍彦,浜名洋,村口篤
- Organizer
  第41回日本免疫学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24650630
[Presentation] A novel human TCR efficient cloning system confers candidate for TCR gene therapy within 10 days.2012
- Author(s)
  Kobayashi E, et al
- Organizer
  27th Annual Meeting of Society for Immunotherapy of Cancer
- Place of Presentation
  North Bethesda, USA
- Data Source
  KAKENHI-PROJECT-24650630
[Presentation] The binding affinity of a soluble TCR-Fc fusion protein is significantly improved by crosslinkage with an anti-Cβ antibody2012
- Author(s)
  小澤龍彦, 小林栄治, 金艾順, 岸裕幸, 村口篤
- Organizer
  第41回日本免疫学会学術集会
- Place of Presentation
  神戸
- Year and Date
  2012-12-05
- Data Source
  KAKENHI-PROJECT-24791019
[Presentation] Detection of antigen-stimulated cytokine secretion in human T-cells at single cell levels on a live cell chip2012
- Author(s)
  岸裕幸, 金艾順, 小林栄治, 小澤龍彦, 浜名洋, 村口篤
- Organizer
  第41回日本免疫学会学術集会
- Place of Presentation
  神戸
- Year and Date
  2012-12-05
- Data Source
  KAKENHI-PROJECT-24791019
[Presentation] 抗原特異的T 細胞受容体遺伝子の超迅速クローニングシステムの構築2012
- Author(s)
  小林栄治, 水腰英四郎, 岸裕幸, 小澤龍彦, 浜名洋, 長井輝美, 金艾順, 金子周一, 村口篤
- Organizer
  第16回日本がん免疫学会総会
- Place of Presentation
  札幌
- Year and Date
  2012-07-26
- Data Source
  KAKENHI-PROJECT-24791019
[Presentation] Cloning of human antigen-specific TCRs can confer the candidates for cancer gene therapy．2012
- Author(s)
  小林　栄治　他
- Organizer
  第41回日本免疫学会学術集会
- Place of Presentation
  神　戸
- Data Source
  KAKENHI-PROJECT-24650630
[Presentation] がんのTCR 遺伝子治療にむけた候補TCR 遺伝子の迅速クローニング法2012
- Author(s)
  岸裕幸, 小林栄治, 水腰英四郎, 小澤龍彦, 金子周一, 村口篤
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PROJECT-24791019
[Presentation] マイクロウェルアレイチップを用いたウサギモノクローナル抗体の迅速作製法の開発2012
- Author(s)
  小澤龍彦, 朴秀虹, 小林栄治, 周越, 櫻井宏明, 安東嗣修, 金艾順, 岸裕幸, 村口篤
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Year and Date
  2012-12-11
- Data Source
  KAKENHI-PROJECT-24791019
[Presentation] A novel human TCR efficient cloning system confers candidate for TCR gene therapy within 10 days2012
- Author(s)
  E.kobayashi, Mizukoshi E., Kishi H., Hamana H., Nagai T., Ozawa T., Nakagawa H., Jin A., Kaneko S., and Muraguchi A
- Organizer
  27th Annual Meeting of Society for Immunotherapy of Cancer
- Place of Presentation
  North Bethesda
- Year and Date
  2012-10-26
- Data Source
  KAKENHI-PROJECT-24791019
[Presentation] メラノーマ患者および健常人PBMC中のCD4+ T細胞の単一細胞レベルでのレパートリー解析．
- Author(s)
  岸　裕幸，小林栄治，杉山大介，西川博嘉，坂口志文，村口　篤．
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25670463
[Presentation] がんペプチドワクチン療法におけるTCRレパートリーの経時的変化の検討．
- Author(s)
  中河秀俊，水腰英四郎，清家拓哉，山宮大典，米島　淳，稲田悠記，木田明彦，梶喜一郎，玉井利克，熊谷将史，寺島健志，北原征明，飯田宗穂，小林栄治，岸　裕幸，村口　篤，金子周一．
- Organizer
  第18回日本がん免疫学会総会
- Place of Presentation
  松山
- Year and Date
  2014-07-30 – 2014-08-01
- Data Source
  KAKENHI-PROJECT-25670463
[Presentation] Functional features of antigen-specific T-cell receptors reflected clinical responses of α-fetoprotein-derived peptides vaccine treatment for advanced hepatocellular carcinoma.
- Author(s)
  Nakagawa H, Mizukoshi E, Kobayashi E, Terashima T, Kitahara M, Iida N, Kishi H, Muraguchi A, Kaneko S.
- Organizer
  The 65th Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  Boston
- Year and Date
  2014-11-07 – 2014-11-11
- Data Source
  KAKENHI-PROJECT-26293237
[Presentation] Functional features of antigen-specific T-cell receptors reflected clinical responses of α-fetoprotein-derived peptides vaccine treatment for advanced hepatocellular carcinoma.
- Author(s)
  Nakagawa H, Mizukoshi E, Kobayashi E, Terashima T, Kitahara M, Iida N, Kishi H, Muraguchi A, Kaneko S.
- Organizer
  The 65th Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  Boston
- Year and Date
  2014-11-07 – 2014-11-11
- Data Source
  KAKENHI-PROJECT-25670463
[Presentation] メラノーマ患者および健常人PBMC中のCD4+ T細胞の単一細胞レベルでのレパートリー解析．
- Author(s)
  岸　裕幸，小林栄治，杉山大介，西川博嘉，坂口志文，村口　篤．
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26293237
[Presentation] GPCR特異的ウサギモノクローナル抗体の迅速作製法の開発．
- Author(s)
  小澤龍彦，朴　秀虹，小林栄治，竹田浩之，澤崎達也，岸　裕幸，村口　篤．
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25670463
[Presentation] 末梢血リンパ球中の抗原特異的CD8+T細胞およびT細胞受容体の網羅的・迅速解析
- Author(s)
  岸　裕幸，小林栄治，水腰英四郎，小澤龍彦，浜名　洋，長井輝美，中河秀俊，金　艾順，金子周一，村口　篤
- Organizer
  第5回造血器腫瘍免疫療法研究会学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24650630
[Presentation] Identification of T cell antigen by an artificial reporter-cell system.
- Author(s)
  Piao X, Kobayashi E, Kishi H, Hamana H, Ozawa T, Muraguchi A.
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  京都
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-26293237
[Presentation] がんペプチドワクチン療法におけるTCRレパートリーの経時的変化の検討．
- Author(s)
  中河秀俊，水腰英四郎，清家拓哉，山宮大典，米島　淳，稲田悠記，木田明彦，梶喜一郎，玉井利克，熊谷将史，寺島健志，北原征明，飯田宗穂，小林栄治，岸　裕幸，村口　篤，金子周一．
- Organizer
  第18回日本がん免疫学会総会
- Place of Presentation
  松山
- Year and Date
  2014-07-30 – 2014-08-01
- Data Source
  KAKENHI-PROJECT-26293237
[Presentation] GPCR特異的ウサギモノクローナル抗体の迅速作製法の開発．
- Author(s)
  小澤龍彦，朴　秀虹，小林栄治，竹田浩之，澤崎達也，岸　裕幸，村口　篤．
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26293237
[Presentation] Identification of T cell antigen by an artificial reporter-cell system.
- Author(s)
  Piao X, Kobayashi E, Kishi H, Hamana H, Ozawa T, Muraguchi A.
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  京都
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-25670463
[]

1. KISHI HIROYUKI (60186210)

# of Collaborated Projects: 6 results

# of Collaborated Products: 95 results
2. MURAGUCHI Atsushi (20174287)

# of Collaborated Projects: 5 results

# of Collaborated Products: 81 results
3. OZAWA Tatsuhiko (10432105)

# of Collaborated Projects: 5 results

# of Collaborated Products: 68 results
4. 浜名洋 (90551549)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
5. 宇高恵子 (40263066)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. KANEKO Shuichi (60185923)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
7. MIZUKOSHI Eishiro (90345611)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
8. 佐藤勉 (40404602)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. NAKASHIMA Akitoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 波多野良

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 下岡清美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 島友子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 戸辺一之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 應原一久

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KOBAYASHI EIJI 小林 栄治

KOBAYASHI Eiji 小林 栄治

Research Projects

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Co-Researchers

がん治療へ向けたサポートCARによる革新的なT細胞受容体療法の開発Principal Investigator

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単一T細胞上でのTCRとp/MHCの相互作用を用いたTCR抗原同定法の開発

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Development of antigen identification system of tumor-infiltrating lymphocytesPrincipal Investigator

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新型ウイルス感染症を標的とした新たな免疫治療法確立のための基盤研究

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Identification of antigens of tumor-infiltrated regulatory T cells and analysis of tumor suppression systems based on the antigensPrincipal Investigator

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Development of Zika fever- and AIDS-peptide vaccine using next generation chip, T-ISAAC

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Development of an innovative lymphocyte chip to establish personalized immuno-therapy for infectious diseases

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抗体療法とT細胞療法を融合したハイブリッド型がん免疫療法の有効性の検証Principal Investigator

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Challenge the infectious diseases and cancers using innovative array technology: Development of hTEC10

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Detection of cancer specific T cells on a chip

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Development of therapeutic hepatitis peptide vaccine using a novel T cell receptor cloning systemPrincipal Investigator

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[Journal Article] Development of a Novel CD26-Targeted Chimeric Antigen Receptor T-Cell Therapy for CD26-Expressing T-Cell Malignancies2023

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[Journal Article] Selection of highly responsive T cell receptors by an analysis combining the expression of multiple markers2023

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KOBAYASHI EIJI 小林栄治

KOBAYASHI Eiji 小林栄治