Mizumoto Kiyohisa 水本清久

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MIZUMOTO Kiyohisa 水本清久

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Researcher Number	80092344
External Links
Affiliation (Current)	2025: 北里大学, 薬学部, 名誉教授
Affiliation (based on the past Project Information) *help	2013: 公益財団法人微生物化学研究会, 微生物化学研究所, 研究アドバイザー 2006: Kitasato University, Professor Emeritus, Vice-President 2006: 北里大学, 名誉教授, 副学長 1997 – 2005: 北里大学, 薬学部, 教授 1991 – 1995: 北里大学, 薬学部, 教授 … More 1986 – 1990: 東京大学, 医科学研究所, 助教授 1987: Institute of Medical Science, University of Tokyo, 医学科研究所, 助教授 1986: 東大, 医科学研究所, 助教授 Less
Review Section/Research Field	Principal Investigator 代謝生物化学 / Biological Sciences / Virology Except Principal Investigator Structural biochemistry / Virology / 分子遺伝学・分子生理学 / Biological pharmacy / Molecular biology / General medical chemistry
Keywords	Principal Investigator キャップ構造 / RNAポリメラーゼII / キャッピング酵素遺伝子 / 転写開始複合体 / センダイウイルス / mRNAグアニル酸転移酵素 / キャッピング酵素 / mRNAキャッピング酵素 / RNA5'-トリホスファターゼ / RNA-dependent RNA polymerase … More / Sendai virus / RNA依存RNAポリメラーゼ / ATP加水分解 / 宿主因子 / RNA依存RNA合成酵素 / インフルエンザウイルス / mRNA(グアニン-7-)メチル基転移酵素 / mRNAキャッピング / in vitro転写反応 / mRNAキャップ構造 / RNAポリメラ-ゼII / Sendai Virus / Transcription Initiation Complex / Yeast / Active Center / Enzyme-GMP Covalent Intermediate / mRNA Guanylyltransferase / mRNA Capping Enzyme / Cap Structure / RNA5'トリフォスファターゼ / 酵素-GMP共有結合中間体 / RNA5'-トリホスファタ-ゼ / センダイヴイルス / 酵母 / 活性中心 / 酵素ーGMP共有結合中間体 / translation repression / mRNA surveillance aystem / Influenza virus / RNA polvmerase II / cap structure / eIF4G / 固定化鋳型 / pol II CTD / RNAポリメラーゼII(pol II) / キャップ結合因子(CBC) / elF4G / pol II-CTD / RNAポリメラーゼII(POl II) / 転写複合体 / mRNA分解制御 / 転写開始 / ポリ(A)鎖 / ノンストップmRNA / キャッピング / プロテアソーム / 翻訳アレスト / mRNA品質管理 / tubulin / mRNA cap / transcription / host factor / negative-strand RNA genome / Paramyxovirus / パラミクソウイルス科 / パラミフソウイルス / ウイルスmRNA / マイナス鎮RNAゲノム / ウイルスLタンパク質 / キャップメチル化酵素 / ウイルスmRNA合成 / チューブリン / mRNAキャップ / 転写 / マイナス鎖RNAゲノム / パラミクソウイルス / 転写開始反応 / RNAポリメサーゼII / 遺伝子破壊 / RNA5′-トリホスファターゼ / キャッピング酵素抗体 / RNAポリメラーゼ【II】転写開始複合体 / 微小管 / HVJ / RNAウイルス / RNAウイルス転写キャッピング / Cryza sativa / Xenopus laevis / キャッピング酵素動態 / 転写因子 / ATP水解要求性 / <in>___ー <vitro>___ー転写 / 前転写開始複合体 … More Except Principal Investigator キャップ構造 / 転写 / インフルエンザウイルス / Transcription / RNA polymerase II / キャッピング酵素 / mRNA / RNAレプリコン / Transcription factor / in vitro transcription / Cap structure / Capping enzyme / in vitro転写反応 / RNA processing / mRNA cap structure / mRNA cap methyltransferase / mRNA capping enzyme / RNAポリメラーゼII / RNAプロセシング / mRNAキャップ構造 / mRNAキャップメチルトランスフェラーゼ / mRNAキャッピング酵素 / 温度感受性変異株 / 出芽酵母 / エンドヌクレアーゼ / ウイルス / 宿主分子 / 病原性 / Cadmium chloride / Sodium arsenite / Heat shock / Shutoff / Temperature-sensitive (ts) mutant / InfluenzaA virus / 蛋白質生合成 / 亜匕酸ソーダ / インフルエンザウィルス / ストレス蛋白質 / 亜ヒ酸ソーダ / 熱ショック / shutoff / regulatory protein / regulatory sequence / regulation of splicing / regulation of replication / regulation of transcription termination / regulation of transcription initiation / 核酸調節配列 / スプライシング調節 / 分子デザイン / 調節タンパク質 / 調節配列 / スプライシング / DNA複製調節 / 転写終結調節 / 転写開始調節 / Protein phosphorylation / C-terminal domain / 転写開始反応 / リン酸化CTD / In vitro / Negative strand RNA genome / RNA dependent RNA polymerase / Endonuclease / Influenza virus / in vitro / マイナス鎖RNAゲノム / RNA依存RNAポリメラーゼ / S.cerevisiae / in vitro 転写反応 / 転写因子 / Temperature-sensitive mutants / Guanylyltransferase / Yeast / Capping / キャッピング / 温度感受性変位株 / グアニル酸転移酵素 / キヤツピング / 研究支援組織 / 教育体制 / プロジェクト / 研究費 / 研究推進 / 終結因子 / アンチュドン / DNA-タンパク質因子複合体 / シグナル領域 / 組織特異的フィブロイン遺伝子発現 / 結合因子 / mRNAスプライシング / 構造変化 / 抗ウイルス薬 / 質量分析フットプリント法 / RNAポリメラーゼ / 組織分布 / 宿主域 / 臓器向性 / トランスジェニックマウス / 複製 / ウイルス蛋白質 / ウイルスRNA / 翻訳 / RNA複製 / パラミキソウイルス / ポリオウイルス / シンポジウム / ニュ-スレタ- / 組織作り / 重点領域研究 Less

Identification of a novel inhibitor of influenza virus polymerase based on inhibition of conformational change required for cap-dependent endonuclease activity
- Principal Investigator
  
  YAMASAKI Manabu
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  Microbial Chemistry Research Foundation
Messenger RNA regulation by 5'-cap structurePrincipal Investigator
- Principal Investigator
  
  MIZUMOTO Kiyohisa
- Project Period (FY)
  2002 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kitasato University
Characterization of influenza virus cap-dependent endonuclease
- Principal Investigator
  
  IWAMA Minako
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kitasato University
Involvement of mRNA capping enzyme in transcription initiation
- Principal Investigator
  
  SHIBAGAKI Yoshio
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kitasato University
mRNAキャッピングシステムの機能Principal Investigator
- Principal Investigator
  
  水本清久
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kitasato University
Structure and function of mRNA capping enzyme system
- Principal Investigator
  
  TSUKAMOTO Toshihiko
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kitasato University
mRNAキャッピングシステムの機能Principal Investigator
- Principal Investigator
  
  水本清久
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kitasato University
Mechanism of transcription of Paramyxovirus genome : Purification and characterization of host factorsPrincipal Investigator
- Principal Investigator
  
  MIZUMOTO Kiyohisa
- Project Period (FY)
  1999 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  Kitasato University
Sructural and function analysis of yeast mRNA capping enzyme in transcription reaction.
- Principal Investigator
  
  SHIBAGAKI Yoshio
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kitasato University
mRNAキャッピングシステムの機能Principal Investigator
- Principal Investigator
  
  水本清久
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kitasato University
Structure and function of mRNA capping enzyme
- Principal Investigator
  
  TSUKAMOTO Toshihiko
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kitasato University
mRNAキャッピングシステムの機能Principal Investigator
- Principal Investigator
  
  水本清久
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kitasato University
RNAレプリコン
- Principal Investigator
  
  野本明男
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
Toward understanding of regulation of mRNA capping and functions of the cap structure.
- Principal Investigator
  
  YAMAGISHI Masahiro
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  Aichi Cancer Center
  National Institute of Genetics
ウイルス病原性の分子的基盤
- Principal Investigator
  
  永井美之
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  Virology
- Research Institution
  The University of Tokyo
RNAレプリコン
- Principal Investigator
  
  野本明男
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Institution
  The University of Tokyo
RNAポリメラ-ゼII転写開始複合体の活性化機構Principal Investigator
- Principal Investigator
  
  水本清久
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
ウイルス研究推進のための調査研究
- Principal Investigator
  
  石浜明
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  Virology
- Research Institution
  National Institute of Genetics
RNAポリメラーゼIIによる転写開始の酵素機構Principal Investigator
- Principal Investigator
  
  水本清久
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
Studies on the Mechanism of Formation of mRNA 5'-Terminal Cap Structure and its FunctionPrincipal Investigator
- Principal Investigator
  
  MIZUMOTO Kiyohisa
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  代謝生物化学
- Research Institution
  The University of Tokyo
DNA・RNAとタンパク質の相互作用による機能ドメインの形成
- Principal Investigator
  
  志村令郎
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Kyoto University
mRNAキャッピング酵素の構造と機能Principal Investigator
- Principal Investigator
  
  水本清久
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  The University of Tokyo
RNAポリメサーゼIIによる転写開始の酵素機構Principal Investigator
- Principal Investigator
  
  水本清久
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
RNA依存RNA合成酵素系による転写シグナルの認識Principal Investigator
- Principal Investigator
  
  水本清久
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  The University of Tokyo
mRNAキャッピング酵素分子とその遺伝子の構造と機能Principal Investigator
- Principal Investigator
  
  水本清久
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  The University of Tokyo
Molecular desighn of regulatory system
- Principal Investigator
  
  AIBA Hiroji
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  分子遺伝学・分子生理学
- Research Institution
  University of Tsukuba
Shutoff of host protein synthesis during infection by influenza A virus
- Principal Investigator
  
  SHIMIZU Kazufumi
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  Nihon University School of Medicine

All 2014 2013 2006 2005 2004 2003 2002 Other

All Journal Article Presentation

[Journal Article] The essential role for the RNA triphosphatase Cetlp in nuclear import of the mRNA capping enzyme Cetlp-Ceglp complex of Saccharomyces cerevisiae2013
- Author(s)
  Naoki Takizawa, Toshinobu Fujiwara, Manabu Yamasaki, Ayako Saito, Akira Fukao, Akio Nomoto, Kiyobisa Mizumoto
- Journal Title
  
  ProsOne
  
  Volume: 8(10) Issue: 10 Pages: e78000-e78000
- DOI
  10.1371/journal.pone.0078000
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J02416, KAKENHI-PROJECT-23390113, KAKENHI-PUBLICLY-24115715, KAKENHI-PROJECT-24659139, KAKENHI-PROJECT-25291007, KAKENHI-PROJECT-25670151, KAKENHI-PROJECT-25871077
[Journal Article] Characterization of monoclonal antibodies directed against the canine distemper virus nucleocapsid protein.2006
- Author(s)
  Masuda。M., Sato, H., Kamata, H., Katsuo, T., Takenaka, A., Miura。R., Yoneda, M., Tsukiyama-Kohara。K., Mizumoto. K. & Kai C
- Journal Title
  
  Comp. Immunol. Microbiol. Infect. Dis. 29
  
  Pages: 157-165
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-14035104
[Journal Article] Characterization of monoclonal antibodies directed against the canine distemper virus nucleocapsid protein.2006
- Author(s)
  Masuda, M, Sato, H., Kamata, H., Katsuo, T., Takenaka, A., Miura, R., Yoneda, M., Tsukiyama-Kohara, K., Mizumoto. K. & Kai, C.
- Journal Title
  
  Comp. Immunol. Microbiol. Infect. Dis. 29
  
  Pages: 157-165
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035104
[Journal Article] The ARF tumor suppressor inhibits BCL6-mediated transcriptionalrepression.2005
- Author(s)
  Suzuki, H., Kurita, M., Mizumoto. K., Moriyama, M., Aiso, S., Nishimoto, I., Matsuoka, M.
- Journal Title
  
  Biochem. Biophys. Res. Commun 326
  
  Pages: 242-248
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-14035104
[Journal Article] The ARF tumor suppressor inhibits BCL6-mediated transcriptional repression.2005
- Author(s)
  Suzuki, H., Kurita, M., Mizumoto, K., Moriyama, M., Aiso, S., Nishimoto, I., Matsuoka, M.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 326
  
  Pages: 242-248
- Data Source
  KAKENHI-PROJECT-14035104
[Journal Article] Sendai virus RNA-dependent RNA polymerase L protein catalyzes cap methylation of virus specific mRNA.2005
- Author(s)
  Ogino, T., Kobayashi, M., Iwama, M., Mizumoto, K.
- Journal Title
  
  J.Biol.Chem. 280
  
  Pages: 4429-4435
- Data Source
  KAKENHI-PROJECT-14035104
[Journal Article] Molecular determinants for subcellular localization of hepatitis C virus core protein.2005
- Author(s)
  Suzuki, R., Sakamoto, S., Tsutsumi, T., Rikimaru, A., Tanaka, K., Shimoike, T., Moriishi, K., Iwasaki, T., Mizumoto. K., Matsuura, Y., Miyamura, T. & Suzuki, T.
- Journal Title
  
  J. Virol. 79
  
  Pages: 1271-1281
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035104
[Journal Article] Sendaivirus RNA-dependent RNA polymerase L protein catalyzes cap methylation of virus specific mRNA.2005
- Author(s)
  T.Ogino, M.Kobatashi, M.Iwama, K.Mizumoto
- Journal Title
  
  J.Biol.Chem. 280
  
  Pages: 4429-4435
- Data Source
  KAKENHI-PROJECT-14035104
[Journal Article] The ARF tumor suppressor inhibits BCL6-mediated trenscriptional repression.2005
- Author(s)
  H.Suzuki, M.Kurita, K.Mizumoto, M.Moriyama, S.Aiso, I.Nishimoto, M.Matsuoke
- Journal Title
  
  Biochem.Biophys.Res.Commun. 326
  
  Pages: 242-248
- Data Source
  KAKENHI-PROJECT-14035104
[Journal Article] Molecular determinants for subcellular localization of hepatitis C virus core protein.2005
- Author(s)
  R.Suzuki, S.Sakamoto, T.Tsutsum, A.Rikimaru, K.Tanaka, T.Shimoike, K.Moriishi, T.Iwasaki, K.Mizumoto, Y.Matsuura, T.Miyamura, T.Suzuki
- Journal Title
  
  J.Virol. 79
  
  Pages: 1271-1281
- Data Source
  KAKENHI-PROJECT-14035104
[Journal Article] Molecular determinants for subcellular localization of hepatitis C virus core protein.2005
- Author(s)
  Suzuki, R., Sakamoto, S., Tsutsumi, T., Rikimaru, A., Tanaka, K., Shimoike, T., Moriishi, K., Iwasaki, T., Mizumoto. K., Matsuura, Y, Miyamura, T., Suzuki, T.
- Journal Title
  
  J. Virol、 79
  
  Pages: 1271-1281
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-14035104
[Journal Article] Sendai virus RNA-dependent RNA polymerase L protein catalyzes capmethylation of virus specific mRNA.2005
- Author(s)
  Ogino, T., Kobayashi, M., Iwama, M., Mizumoto. K.
- Journal Title
  
  J. Biol. Chem、 280
  
  Pages: 4429-4435
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-14035104
[Journal Article] Molecular determinants for subcellular localization of hepatitis C virus core protein.2005
- Author(s)
  Suzuki, R., Sakamoto, S., Tsutsumi, T., Rikimaru, A, Tanaka, K., Shimoike, T., Moriishi, K., Iwasaki, T., Mizumoto, K., Masuura, Y., Miyamura, T., Susuki, T.
- Journal Title
  
  J.Virol. 79
  
  Pages: 1271-1281
- Data Source
  KAKENHI-PROJECT-14035104
[Journal Article] Sendai viras RNA-dependent RNA polymerase L protein catalyzes cap methylation of virus specific mRNA.2005
- Author(s)
  Ogino, T., Kobayashi, M., Iwama, M. & Mizumoto. K.
- Journal Title
  
  J. Biol. Chem. 280
  
  Pages: 4429-4435
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035104
[Journal Article] Functional interaction of mRNA capping enzyme with RNA polymerase II2004
- Author(s)
  Wada, K., Shibagaki, Y., Hisatake, K., Fukuda, A., Mizumoto, K.
- Journal Title
  
  Seikagaku 76
  
  Pages: 855-855
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14580630
[Journal Article] Overexpression of CR/periphilin downregulates Cdc7 expression and in duces S-phase arrest.2004
- Author(s)
  Kurita, M., Suzuki, H., Masai, H., Mizumoto, K., Ogata, E., Nishimoto, I., Aiso, S. & Matsuoka, M.
- Journal Title
  
  Biochem. Bwphys. Res. Commun. 324
  
  Pages: 554-561
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035104
[Journal Article] Overexpression of CR/periphilin downregulates Cdc7 expression and inducesS-phase arrest.2004
- Author(s)
  Kurita. M., Suzuki, H., Masai, H., Mizumoto. K.. Ogata, E., Nishimoto, I., Aiso, S., Matsuoka, M.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 324
  
  Pages: 554-561
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-14035104
[Journal Article] Mulyople domains of the mouse P19 (ARF)tumor suppressor are involved inp53-independent apoptosis.2003
- Author(s)
  Matsuoka, M., Kurita, M., Sudo, H., Mizumoto. K. Nishimoto, I., Ogata, E.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 301
  
  Pages: 1000-1010
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-14035104
[Journal Article] Interaction of cellular tubulin with Sendai virus M orotein regulates transcription of viral genome.2003
- Author(s)
  Ogino, T., Iwama, M., Ohsawa, Y. & Mizumoto. K.
- Journal Title
  
  Biochem. Biophys. Res. Commn. 311
  
  Pages: 283-293
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035104
[Journal Article] The role of mRNA capping enzyme in pol II transcription initiation2003
- Author(s)
  Shibagaki, Y., Nojima, T., Matsui, H., Hisatake, K., Fukuda, A., Mizumoto, K.
- Journal Title
  
  The New Frontier of RNA Science RNA 2003 Kyoto Abstract
  
  Pages: 175-175
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14580630
[Journal Article] pl9ARF-induced p53-independent apoptosis largely occurs through BAX.2003
- Author(s)
  Suzuki, H., Kurita, M., Mizumoto. K., Nishimoto, I., Ogata, E., Matsuoka, M.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 312
  
  Pages: 1273-1277
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-14035104
[Journal Article] Interaction of cellular tubulin with Sendai virus M protein regulatestranscription of viral genome.2003
- Author(s)
  Ogino, T., Iwama, M., Ohsawa, Y., Mizumoto, K.
- Journal Title
  
  Biochem. Biophys. Res. Comm. n 311
  
  Pages: 283-293
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-14035104
[Journal Article] pl9ARF-induced p53-independent apoptosis largely occurs through BAX.2003
- Author(s)
  Suzuki, H., Kurita, M., Mizumoto. K.. Nishimoto. I., Ogata, E. & Matsuoka, M.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 312
  
  Pages: 1273-1277
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035104
[Journal Article] The role of mRNA capping enzyme in pol II transcription initiation2003
- Author(s)
  Shibagaki, Y., Nojima, T., Hisatake, K., Fukuda, A., Mizumoto, K.
- Journal Title
  
  Seikagaku 75
  
  Pages: 939-939
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14580630
[Journal Article] Mulyople domains of the mouse PI 9 (ARF) tumor suppressor are involved in p53-independent apoptosis.2003
- Author(s)
  Matsuoka, M., Kurita, M., Sudo, H., Mizumoto. K., Nishimoto. I., Ogata, E.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 301
  
  Pages: 1000-1010
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035104
[Journal Article] Minimum molecular architectures for transcription and replication of the influenza virus.2002
- Author(s)
  Honda, A., Mizumoto. K. & Ishihama, A.
- Journal Title
  
  Proc. Nail. Acad. Sci. USA 99
  
  Pages: 13166-13171
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035104
[Journal Article] Involvement of mRNA capping enzyme in pol II initiation complex2002
- Author(s)
  Shibagaki, Y., Hisatake, K., Fukuda, A., Fukamachi, N., Tsukamoto, T., Mizumoto, K.
- Journal Title
  
  Seikagaku 74
  
  Pages: 1001-1001
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14580630
[Journal Article] Minimum molecular architectures for transcription and replication of the influenza virus.2002
- Author(s)
  Honda, A., Mizumoto. K. &Ishihama, A.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA 99
  
  Pages: 13166-13171
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-14035104
[Journal Article] Differential effect of ik3-l/Cables on p53- and p73-induced cell death.2002
- Author(s)
  Tsuji, K., Mizumoto. K., Yamochi, T., Nishimoto, I., Matsuoka, M.
- Journal Title
  
  J. Biol. Chem. 277
  
  Pages: 2951-2957
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035104
[Journal Article] Interaction of S-adenosylhomocysteine hydrolase of Xenopus laevis withmRNA(guanine-7-)methyltransferase : Implication on its nuclear compartmentalisation and on cap methvlation of hnRNA.2002
- Author(s)
  Radomski, N., Barreto, G., Kaufmann, C, Yokosuka, J., Mizumoto, K. & Dreyer, C.
- Journal Title
  
  Biochem. Biophys. Acta 1590
  
  Pages: 93-102
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-14035104
[Journal Article] Differential effect of ik3-I/Cables on p53- and p73-induced cell death.2002
- Author(s)
  Tsuji, K., Mizumoto. K, Yamochi, T., Nishimoto, I., Matsuoka, M.
- Journal Title
  
  J. Biol. Chem. 277
  
  Pages: 2951-2957
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-14035104
[Journal Article] Proteomic analysis of human brain identifies -enolase as a novel autoantigen in Hashimoto's encephalopathy.2002
- Author(s)
  Ochi, H., Horiuchi, I., Araki, N., Toda, T., Araki, T., Sato, K., Murai, H., Osoegawa, M., Yamada, T., Okamura, K., Ogino, T., Mizumoto. K., Yamashita, H., Saya, H., J. Kira
- Journal Title
  
  FEBS Lett. 528
  
  Pages: 197-202
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035104
[Journal Article] Interaction of S-adenosylhomocysteine hydrolase of Xenopus laevis with mRNA(guanine-7-)methyltransferase: Implication on its nuclear compartmentalisation and on cap methylation of hnRNA.2002
- Author(s)
  Radomski, N., Barreto, G., Kaufmann, C, Yokosuka, J., Mizumoto. K. & Dreyer, C.
- Journal Title
  
  Biochem. Biophys. Acta 1590
  
  Pages: 93-102
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035104
[Journal Article] p53-independent apoptosis is induced by the pl9ARF tumor suppressor.2002
- Author(s)
  Tsuji, K., Mizumoto. K., Sudo, H., Kouyama, K., Ogata, E. & Matsuoka, M.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 295
  
  Pages: 621-629
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035104
[Journal Article] Proteomic analysis of human brain identifies -enolase as a novel autoantigen in Hashimoto's encephalopathy.2002
- Author(s)
  Ochi, H., Horiuchi, I., Araki, N., Toda, T., Araki, T., Sato, K., Murai, H., Osoegawa, M., Yamada, T., Okamura, K., Ogino, T., Mizumoto. K., Yamashita, H., Saya, H., J. Kira
- Journal Title
  
  FEBS Lett 528
  
  Pages: 197-202
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-14035104
[Journal Article] p53-independent apoptosis is induced by the pl9ARF tumor suppressor.2002
- Author(s)
  Tsuji, K., Mizumoto. K., Sudo, H., Kouyama, K., Ogata, E., Matsuoka, M.
- Journal Title
  
  Biochem. Biophys. Res. Commun 295
  
  Pages: 621-629
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-14035104
[Presentation] 新規RNA 5'-トリホスファターゼ阻害物質MI481-42F6 A, B, CおよびDに関する研究2014
- Author(s)
  梅北まや、五十嵐雅之、澤竜一、山崎学、林千草、波多野和樹、藤原俊伸、水本清久、野本明男
- Organizer
  日本農芸化学会2014年度大会
- Place of Presentation
  明治大学生田キャンパス(川崎市)
- Year and Date
  2014-03-30
- Data Source
  KAKENHI-PROJECT-24659139
[Presentation] インフルエンザウイルスRNAポリメラーゼがもつキャップ依存エンドヌクレアーゼ活性を阻害する低分子化合物の探索2013
- Author(s)
  山崎学、滝沢直己、藤原俊伸、水本清久、野本明男
- Organizer
  第61回日本ウイルス学会学術集会
- Place of Presentation
  神戸国際会議場(神戸市)
- Year and Date
  2013-11-11
- Data Source
  KAKENHI-PROJECT-24659139
[Presentation] Analysis of capped RNA by boronate affinity PAGE2006
- Author(s)
  Yoshio Shibagaki, Kiyohisa Mizumoto
- Organizer
  20th IUBMB International Congress of Biochemistry and Morecular Biology and nth FAOBMB Congress
- Place of Presentation
  Kyoto, Japan
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14035104
[Presentation] The mechanism of capping of RNA polymerase II transcripts - The timing of cap formation2006
- Author(s)
  Tetsuro Komatsu, Yoshio Shibagaki, Kiyohisa Mizumoto
- Organizer
  20th IUBMB International Congress of Biochemistry andMorecular Biology and nth FAOBMB Congress
- Place of Presentation
  Kyoto, Japan
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14035104
[Presentation] Analysis of capped RNA by boronate affinity PAGE2006
- Author(s)
  Yoshio Shibagaki, Kiyohisa Mizumoto
- Organizer
  20th IUBMB International Congress of Biochemistry and Morecular Biology and 11th FAOBMB Congress
- Place of Presentation
  Kyoto
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035104
[Presentation] Characterizaation of cap-dependent endonuclease activily associated with influenza vims RNA polymerase.- the comparison of type A and type B viruses2006
- Author(s)
  Chitose Wakai, Takatoshi Saito, Minako Iwama, Yujiro Suzuki, Kiyohisa Mizumoto
- Organizer
  20th IUBMB International Congress of Biochemistry and Morecular Biology and 11th FAOBMB Congress
- Place of Presentation
  Kyoto
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035104
[Presentation] The mechanism of capping of RNA polymerase II transcripts - The timing of cap formation2006
- Author(s)
  Tetsuro Komatsu, Yoshio Shibagaki, Kiyohisa Mizumoto
- Organizer
  20th IUBMB International Congress of Biochemistry and Morecular Biology and 11th FAOBMB Congress
- Place of Presentation
  Kyoto
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035104
[Presentation] Characterizaation of cap-dependent endonuclease activity associated with influenzavirus RNA polymerase - the comparison of type A and type B viruses2006
- Author(s)
  Chitose Wakai, Takatoshi Saito, MinakoIwama, Yujiro Suzuki, Kiyohisa Mizumoto
- Organizer
  20th IUBMB International Congress of Biochemistry and Morecular Biology and l 1th FAOBMB Congress
- Place of Presentation
  Kyoto, Japan
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14035104
[Presentation] Functional analysis of helicase and kinase activities of TFIIH2005
- Author(s)
  Hisatake K, Fukuda A, Shibagaki Y, Nakafuo T, Shimada M, Mizumoto K, Nogi Y
- Organizer
  The 26th Annual Meeting The Molecular Biology Society of Japan, Symposium
- Place of Presentation
  Kobe
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035104
[Presentation] Catalytic Properties of Capped RNA Endonuclease Associated with InfluenzaVirus RNA Polym erase - The Comparison of Type A and Type B Viruses2005
- Author(s)
  Wakai C, Saito T, Iwama M, Suzuki Y, Mizumoto K
- Organizer
  XIIIth International Congress of Virology
- Place of Presentation
  San Francisco, USA
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14035104
[Presentation] Catalytic Properties of Capped RNA Endonuclease Associated with Influenza Virus RNA Polymerase - The Comparison of Type A and Type B Viruses2005
- Author(s)
  Wakai C, Saito T, Iwama M, Suzuki Y, Mizumoto K
- Organizer
  XIIIth International Congress of Virology
- Place of Presentation
  San Francisco
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035104
[Presentation] Analysis of protein factors required for in vitro transcription of Sendai virus genome.2004
- Author(s)
  Mizumoto K
- Organizer
  The 25th Annual Meeting The molecular Biology Society of Japan, Workshop
- Place of Presentation
  Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035104
[Presentation] センダイウイルスRNA依存RNAポリメラーゼ(Lタンパク質)はウイルス特異的のmRNAのキャップをメチル化する2003
- Author(s)
  荻野朝朗, 小林正樹, 岩間美奈子, 水本清久
- Organizer
  国際シンポジウム「RNA研究のフロンティア」
- Place of Presentation
  Kyoto, Japan
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14035104
[Presentation] 転写初期反応におけるRNA polymerase II によるmRNAキャップ化酵素の役割2003
- Author(s)
  柴垣芳夫, 野島孝之, 松井博紀, 久武幸司, 福田綾, 水本清久
- Organizer
  国際シンポジウム「RNA研究のフロンティア」
- Place of Presentation
  Kyoto, Japan
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14035104
[Presentation] Sendai virus RNA-dependent RNA polymerase (L protein) catalyzes cap methylation of virus-specific mRNA2003
- Author(s)
  Ogino T, Kobayashi M, Iwama M, Mizumoto K.
- Organizer
  RNA2003 Kyoto
- Place of Presentation
  Kyoto
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035104
[Presentation] THIIHのヘリガーゼとキナーゼ活性の機能解析2003
- Author(s)
  久武幸司, 福田綾, 柴垣芳夫, 中太智義, 嶋田美穂, 水本清久, 禾康壽
- Organizer
  第26回日本分子生物学会年会シンポジウム
- Place of Presentation
  神戸、日本
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14035104
[Presentation] インフルエンザウイルスRNAポリメラーゼの活性と特異性の制御2003
- Author(s)
  本田文江, 岡本拓人, 水本清久, 清水一史, 宮尾憲孝, 石浜明
- Organizer
  日本ウイルス学会第51回学術集会・総会ワークシヨップ
- Place of Presentation
  京都、日本
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14035104
[Presentation] Involvement of mRNA capping enzyme in transcription initiation by RNA polymerase II2003
- Author(s)
  Shibagaki Y, Nojima T, Matsui H, Hisatake K, Fukuda A, Mizumoto K.
- Organizer
  RNA2003 Kyoto
- Place of Presentation
  Kyoto
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035104
[Presentation] Regulation of activities and specificity of influenza vims RNA polymerase2002
- Author(s)
  Honda F, Okamoto T, Mizumoto K, Shimizu K, Miyao K, Ishihama A.
- Organizer
  The 51st Annual Meeting of The Japanese Society for Virology
- Place of Presentation
  Kyoto
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14035104
[Presentation] センダイウイルスゲノムの転写に関与する宿主因子群の解析2002
- Author(s)
  水本清久
- Organizer
  第25回日本分子生物学会年会フーグショップ
- Place of Presentation
  横浜、日本
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14035104
[Presentation] 新規RNA5’-トリホスファターゼ阻害物質MI481-42F6 A,B,CおよびDに関する研究
- Author(s)
  梅北まや、五十嵐雅之、澤竜一、山崎学、林千草、波多野和樹、藤原俊伸、水本清久、野本明男
- Organizer
  日本農芸化学会2014年度大会
- Place of Presentation
  明治大学生田キャンパス（川崎市）
- Data Source
  KAKENHI-PROJECT-24659139
[Presentation] インフルエンザウイルスRNAポリメラーゼがもつキャップ依存エンドヌクレアーゼ活性を阻害する低分子化合物の探索
- Author(s)
  山崎学、滝沢直己、藤原俊伸、水本清久、野本明男
- Organizer
  第61回日本ウイルス学会学術集会
- Place of Presentation
  神戸国際会議場（神戸市）
- Data Source
  KAKENHI-PROJECT-24659139

1. 野本明男 (70112670)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. 石浜明 (80019869)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. TSUKAMOTO Toshihiko (10236862)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. 永井美之 (20022874)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. 永田恭介 (40180492)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. TANAKA Michiko (60114550)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. OHSHIMA Yasumi (90037606)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. IWAMA Minako (10223421)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. SHIBAGAKI Yoshio (90235565)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
10. 岡田吉美 (30011703)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. YAMASAKI Manabu (50442570)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
12. TAKIZAWA Naoki (50448502)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. YAMAGISHI Masahiro (00220252)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. OGINO Tomoaki (80312213)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. INADA Toshifumi (40242812)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. HISATAKE Koji (70271236)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
17. AIBA Hiroji (20025662)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. HANDA Hiroshi (80107432)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. ISHII Shunsuke (00124785)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. NAKAMURA Yoshikazu (40114590)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. SHIMIZU Kazufumi (50004677)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. SUGANO Junjo (80192756)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 吉田光昭 (80012607)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 豊島久真男 (90029760)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 吉倉廣 (60012754)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 豊田春香 (10197973)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 田代真人 (90111343)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 岩崎憲太郎 (90009986)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 志村令郎 (60025426)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 重定勝哉 (40009626)

# of Collaborated Projects: 1 results

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31. 山尾文明 (10158074)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 鈴木義昭 (50132733)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 有賀寛芳 (20143505)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 渋田博 (70012721)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Mizumoto Kiyohisa 水本 清久

MIZUMOTO Kiyohisa 水本 清久

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Messenger RNA regulation by 5'-cap structurePrincipal Investigator

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mRNAキャッピングシステムの機能Principal Investigator

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mRNAキャッピングシステムの機能Principal Investigator

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Mechanism of transcription of Paramyxovirus genome : Purification and characterization of host factorsPrincipal Investigator

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mRNAキャッピングシステムの機能Principal Investigator

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mRNAキャッピングシステムの機能Principal Investigator

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Mizumoto Kiyohisa 水本清久

MIZUMOTO Kiyohisa 水本清久