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Mizumoto Kiyohisa  水本 清久

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MIZUMOTO Kiyohisa  水本 清久

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Researcher Number 80092344
External Links
Affiliation (Current) 2022: 北里大学, 薬学部, 名誉教授
Affiliation (based on the past Project Information) *help 2013: 公益財団法人微生物化学研究会, 微生物化学研究所, 研究アドバイザー
2006: Kitasato University, Professor Emeritus, Vice-President
2006: 北里大学, 名誉教授, 副学長
1997 – 2005: 北里大学, 薬学部, 教授
1991 – 1995: 北里大学, 薬学部, 教授 … More
1986 – 1990: 東京大学, 医科学研究所, 助教授
1987: Institute of Medical Science, University of Tokyo, 医学科研究所, 助教授
1986: 東大, 医科学研究所, 助教授 Less
Review Section/Research Field
Principal Investigator
Virology / Biological Sciences / 代謝生物化学
Except Principal Investigator
Structural biochemistry / Virology / General medical chemistry / Molecular biology / Biological pharmacy / 分子遺伝学・分子生理学
Keywords
Principal Investigator
キャップ構造 / キャッピング酵素遺伝子 / RNAポリメラーゼII / 転写開始複合体 / mRNAグアニル酸転移酵素 / センダイウイルス / mRNAキャッピング酵素 / キャッピング酵素 / RNA5'-トリホスファターゼ / RNAポリメラ-ゼII … More / mRNAキャップ構造 / in vitro転写反応 / mRNAキャッピング / mRNA(グアニン-7-)メチル基転移酵素 / インフルエンザウイルス / RNA依存RNA合成酵素 / 宿主因子 / ATP加水分解 / RNA依存RNAポリメラーゼ / Sendai virus / RNA-dependent RNA polymerase / 前転写開始複合体 / <in>___ー <vitro>___ー転写 / ATP水解要求性 / 転写因子 / キャッピング酵素動態 / Xenopus laevis / Cryza sativa / RNAウイルス転写キャッピング / RNAウイルス / HVJ / 微小管 / RNAポリメラーゼ【II】転写開始複合体 / キャッピング酵素抗体 / RNA5′-トリホスファターゼ / 遺伝子破壊 / RNAポリメサーゼII / 転写開始反応 / パラミクソウイルス / マイナス鎖RNAゲノム / 転写 / mRNAキャップ / チューブリン / ウイルスmRNA合成 / キャップメチル化酵素 / ウイルスLタンパク質 / マイナス鎮RNAゲノム / ウイルスmRNA / パラミフソウイルス / パラミクソウイルス科 / Paramyxovirus / negative-strand RNA genome / host factor / transcription / mRNA cap / tubulin / mRNA品質管理 / 翻訳アレスト / プロテアソーム / キャッピング / ノンストップmRNA / ポリ(A)鎖 / 転写開始 / mRNA分解制御 / 転写複合体 / RNAポリメラーゼII(POl II) / pol II-CTD / elF4G / キャップ結合因子(CBC) / RNAポリメラーゼII(pol II) / pol II CTD / 固定化鋳型 / eIF4G / cap structure / RNA polvmerase II / Influenza virus / mRNA surveillance aystem / translation repression / 酵素ーGMP共有結合中間体 / 活性中心 / 酵母 / センダイヴイルス / RNA5'-トリホスファタ-ゼ / 酵素-GMP共有結合中間体 / RNA5'トリフォスファターゼ / Cap Structure / mRNA Capping Enzyme / mRNA Guanylyltransferase / Enzyme-GMP Covalent Intermediate / Active Center / Yeast / Transcription Initiation Complex / Sendai Virus … More
Except Principal Investigator
キャップ構造 / インフルエンザウイルス / 転写 / RNAレプリコン / mRNA / キャッピング酵素 / RNA polymerase II / Transcription / 病原性 / 宿主分子 / ウイルス / エンドヌクレアーゼ / 出芽酵母 / 温度感受性変異株 / mRNAキャッピング酵素 / mRNAキャップメチルトランスフェラーゼ / mRNAキャップ構造 / RNAプロセシング / RNAポリメラーゼII / mRNA capping enzyme / mRNA cap methyltransferase / mRNA cap structure / RNA processing / in vitro転写反応 / Capping enzyme / Cap structure / in vitro transcription / Transcription factor / 重点領域研究 / 組織作り / ニュ-スレタ- / シンポジウム / ポリオウイルス / パラミキソウイルス / RNA複製 / 翻訳 / ウイルスRNA / ウイルス蛋白質 / 複製 / トランスジェニックマウス / 臓器向性 / 宿主域 / 組織分布 / RNAポリメラーゼ / 質量分析フットプリント法 / 抗ウイルス薬 / 構造変化 / mRNAスプライシング / 結合因子 / 組織特異的フィブロイン遺伝子発現 / シグナル領域 / DNA-タンパク質因子複合体 / アンチュドン / 終結因子 / 研究推進 / 研究費 / プロジェクト / 教育体制 / 研究支援組織 / キヤツピング / グアニル酸転移酵素 / 温度感受性変位株 / キャッピング / Capping / Yeast / Guanylyltransferase / Temperature-sensitive mutants / 転写因子 / in vitro 転写反応 / S.cerevisiae / RNA依存RNAポリメラーゼ / マイナス鎖RNAゲノム / in vitro / Influenza virus / Endonuclease / RNA dependent RNA polymerase / Negative strand RNA genome / In vitro / リン酸化CTD / 転写開始反応 / C-terminal domain / Protein phosphorylation / 転写開始調節 / 転写終結調節 / DNA複製調節 / スプライシング / 調節配列 / 調節タンパク質 / 分子デザイン / スプライシング調節 / 核酸調節配列 / regulation of transcription initiation / regulation of transcription termination / regulation of replication / regulation of splicing / regulatory sequence / regulatory protein / shutoff / 熱ショック / 亜ヒ酸ソーダ / ストレス蛋白質 / インフルエンザウィルス / 亜匕酸ソーダ / 蛋白質生合成 / InfluenzaA virus / Temperature-sensitive (ts) mutant / Shutoff / Heat shock / Sodium arsenite / Cadmium chloride Less
  • Research Projects

    (27 results)
  • Research Products

    (58 results)
  • Co-Researchers

    (35 People)
  •  Identification of a novel inhibitor of influenza virus polymerase based on inhibition of conformational change required for cap-dependent endonuclease activity

    • Principal Investigator
      YAMASAKI Manabu
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      General medical chemistry
    • Research Institution
      Microbial Chemistry Research Foundation
  •  Messenger RNA regulation by 5'-cap structurePrincipal Investigator

    • Principal Investigator
      MIZUMOTO Kiyohisa
    • Project Period (FY)
      2002 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kitasato University
  •  Characterization of influenza virus cap-dependent endonuclease

    • Principal Investigator
      IWAMA Minako
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kitasato University
  •  Involvement of mRNA capping enzyme in transcription initiation

    • Principal Investigator
      SHIBAGAKI Yoshio
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Structural biochemistry
    • Research Institution
      Kitasato University
  •  mRNAキャッピングシステムの機能Principal Investigator

    • Principal Investigator
      水本 清久
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kitasato University
  •  Structure and function of mRNA capping enzyme system

    • Principal Investigator
      TSUKAMOTO Toshihiko
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Structural biochemistry
    • Research Institution
      Kitasato University
  •  mRNAキャッピングシステムの機能Principal Investigator

    • Principal Investigator
      水本 清久
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kitasato University
  •  Mechanism of transcription of Paramyxovirus genome : Purification and characterization of host factorsPrincipal Investigator

    • Principal Investigator
      MIZUMOTO Kiyohisa
    • Project Period (FY)
      1999 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Virology
    • Research Institution
      Kitasato University
  •  Sructural and function analysis of yeast mRNA capping enzyme in transcription reaction.

    • Principal Investigator
      SHIBAGAKI Yoshio
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Structural biochemistry
    • Research Institution
      Kitasato University
  •  mRNAキャッピングシステムの機能Principal Investigator

    • Principal Investigator
      水本 清久
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kitasato University
  •  Structure and function of mRNA capping enzyme

    • Principal Investigator
      TSUKAMOTO Toshihiko
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Structural biochemistry
    • Research Institution
      Kitasato University
  •  mRNAキャッピングシステムの機能Principal Investigator

    • Principal Investigator
      水本 清久
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kitasato University
  •  RNAレプリコン

    • Principal Investigator
      野本 明男
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  Toward understanding of regulation of mRNA capping and functions of the cap structure.

    • Principal Investigator
      YAMAGISHI Masahiro
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Molecular biology
    • Research Institution
      Aichi Cancer Center
      National Institute of Genetics
  •  ウイルス病原性の分子的基盤

    • Principal Investigator
      永井 美之
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Virology
    • Research Institution
      The University of Tokyo
  •  RNAレプリコン

    • Principal Investigator
      野本 明男
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Institution
      The University of Tokyo
  •  RNAポリメラ-ゼII転写開始複合体の活性化機構Principal Investigator

    • Principal Investigator
      水本 清久
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  ウイルス研究推進のための調査研究

    • Principal Investigator
      石浜 明
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Virology
    • Research Institution
      National Institute of Genetics
  •  RNAポリメラーゼIIによる転写開始の酵素機構Principal Investigator

    • Principal Investigator
      水本 清久
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  Studies on the Mechanism of Formation of mRNA 5'-Terminal Cap Structure and its FunctionPrincipal Investigator

    • Principal Investigator
      MIZUMOTO Kiyohisa
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      代謝生物化学
    • Research Institution
      The University of Tokyo
  •  DNA・RNAとタンパク質の相互作用による機能ドメインの形成

    • Principal Investigator
      志村 令郎
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      Kyoto University
  •  mRNAキャッピング酵素の構造と機能Principal Investigator

    • Principal Investigator
      水本 清久
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      The University of Tokyo
  •  RNAポリメサーゼIIによる転写開始の酵素機構Principal Investigator

    • Principal Investigator
      水本 清久
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  RNA依存RNA合成酵素系による転写シグナルの認識Principal Investigator

    • Principal Investigator
      水本 清久
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      The University of Tokyo
  •  mRNAキャッピング酵素分子とその遺伝子の構造と機能Principal Investigator

    • Principal Investigator
      水本 清久
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      The University of Tokyo
  •  Molecular desighn of regulatory system

    • Principal Investigator
      AIBA Hiroji
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      分子遺伝学・分子生理学
    • Research Institution
      University of Tsukuba
  •  Shutoff of host protein synthesis during infection by influenza A virus

    • Principal Investigator
      SHIMIZU Kazufumi
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Virology
    • Research Institution
      Nihon University School of Medicine

All 2014 2013 2006 2005 2004 2003 2002 Other

All Journal Article Presentation

  • [Journal Article] The essential role for the RNA triphosphatase Cet1p in nuclear import of the mRNA capping enzyme Cet1p-Ceg1p complex of Saccharomyces cerevisiae2013

    • Author(s)
      Naoki Takizawa, Toshinobu Fujiwara, Manabu Yamasaki, Ayako Saito, Akira Fukao, Akio Nomoto, Kiyobisa Mizumoto
    • Journal Title

      PLoS One

      Volume: 8(10)

    • DOI

      10.1371/journal.pone.0078000

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J02416, KAKENHI-PROJECT-23390113, KAKENHI-PUBLICLY-24115715, KAKENHI-PROJECT-24659139, KAKENHI-PROJECT-25291007, KAKENHI-PROJECT-25670151, KAKENHI-PROJECT-25871077
  • [Journal Article] Characterization of monoclonal antibodies directed against the canine distemper virus nucleocapsid protein.2006

    • Author(s)
      Masuda。M., Sato, H., Kamata, H., Katsuo, T., Takenaka, A., Miura。R., Yoneda, M., Tsukiyama-Kohara。K., Mizumoto. K. & Kai C
    • Journal Title

      Comp. Immunol. Microbiol. Infect. Dis. 29

      Pages: 157-165

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-14035104
  • [Journal Article] Characterization of monoclonal antibodies directed against the canine distemper virus nucleocapsid protein.2006

    • Author(s)
      Masuda, M, Sato, H., Kamata, H., Katsuo, T., Takenaka, A., Miura, R., Yoneda, M., Tsukiyama-Kohara, K., Mizumoto. K. & Kai, C.
    • Journal Title

      Comp. Immunol. Microbiol. Infect. Dis. 29

      Pages: 157-165

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14035104
  • [Journal Article] The ARF tumor suppressor inhibits BCL6-mediated transcriptionalrepression.2005

    • Author(s)
      Suzuki, H., Kurita, M., Mizumoto. K., Moriyama, M., Aiso, S., Nishimoto, I., Matsuoka, M.
    • Journal Title

      Biochem. Biophys. Res. Commun 326

      Pages: 242-248

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-14035104
  • [Journal Article] The ARF tumor suppressor inhibits BCL6-mediated transcriptional repression.2005

    • Author(s)
      Suzuki, H., Kurita, M., Mizumoto, K., Moriyama, M., Aiso, S., Nishimoto, I., Matsuoka, M.
    • Journal Title

      Biochem.Biophys.Res.Commun. 326

      Pages: 242-248

    • Data Source
      KAKENHI-PROJECT-14035104
  • [Journal Article] Sendai virus RNA-dependent RNA polymerase L protein catalyzes cap methylation of virus specific mRNA.2005

    • Author(s)
      Ogino, T., Kobayashi, M., Iwama, M., Mizumoto, K.
    • Journal Title

      J.Biol.Chem. 280

      Pages: 4429-4435

    • Data Source
      KAKENHI-PROJECT-14035104
  • [Journal Article] Molecular determinants for subcellular localization of hepatitis C virus core protein.2005

    • Author(s)
      Suzuki, R., Sakamoto, S., Tsutsumi, T., Rikimaru, A., Tanaka, K., Shimoike, T., Moriishi, K., Iwasaki, T., Mizumoto. K., Matsuura, Y., Miyamura, T. & Suzuki, T.
    • Journal Title

      J. Virol. 79

      Pages: 1271-1281

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14035104
  • [Journal Article] Sendaivirus RNA-dependent RNA polymerase L protein catalyzes cap methylation of virus specific mRNA.2005

    • Author(s)
      T.Ogino, M.Kobatashi, M.Iwama, K.Mizumoto
    • Journal Title

      J.Biol.Chem. 280

      Pages: 4429-4435

    • Data Source
      KAKENHI-PROJECT-14035104
  • [Journal Article] The ARF tumor suppressor inhibits BCL6-mediated trenscriptional repression.2005

    • Author(s)
      H.Suzuki, M.Kurita, K.Mizumoto, M.Moriyama, S.Aiso, I.Nishimoto, M.Matsuoke
    • Journal Title

      Biochem.Biophys.Res.Commun. 326

      Pages: 242-248

    • Data Source
      KAKENHI-PROJECT-14035104
  • [Journal Article] Molecular determinants for subcellular localization of hepatitis C virus core protein.2005

    • Author(s)
      R.Suzuki, S.Sakamoto, T.Tsutsum, A.Rikimaru, K.Tanaka, T.Shimoike, K.Moriishi, T.Iwasaki, K.Mizumoto, Y.Matsuura, T.Miyamura, T.Suzuki
    • Journal Title

      J.Virol. 79

      Pages: 1271-1281

    • Data Source
      KAKENHI-PROJECT-14035104
  • [Journal Article] Molecular determinants for subcellular localization of hepatitis C virus core protein.2005

    • Author(s)
      Suzuki, R., Sakamoto, S., Tsutsumi, T., Rikimaru, A., Tanaka, K., Shimoike, T., Moriishi, K., Iwasaki, T., Mizumoto. K., Matsuura, Y, Miyamura, T., Suzuki, T.
    • Journal Title

      J. Virol、 79

      Pages: 1271-1281

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-14035104
  • [Journal Article] Sendai virus RNA-dependent RNA polymerase L protein catalyzes capmethylation of virus specific mRNA.2005

    • Author(s)
      Ogino, T., Kobayashi, M., Iwama, M., Mizumoto. K.
    • Journal Title

      J. Biol. Chem、 280

      Pages: 4429-4435

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-14035104
  • [Journal Article] Molecular determinants for subcellular localization of hepatitis C virus core protein.2005

    • Author(s)
      Suzuki, R., Sakamoto, S., Tsutsumi, T., Rikimaru, A, Tanaka, K., Shimoike, T., Moriishi, K., Iwasaki, T., Mizumoto, K., Masuura, Y., Miyamura, T., Susuki, T.
    • Journal Title

      J.Virol. 79

      Pages: 1271-1281

    • Data Source
      KAKENHI-PROJECT-14035104
  • [Journal Article] Sendai viras RNA-dependent RNA polymerase L protein catalyzes cap methylation of virus specific mRNA.2005

    • Author(s)
      Ogino, T., Kobayashi, M., Iwama, M. & Mizumoto. K.
    • Journal Title

      J. Biol. Chem. 280

      Pages: 4429-4435

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14035104
  • [Journal Article] Functional interaction of mRNA capping enzyme with RNA polymerase II2004

    • Author(s)
      Wada, K., Shibagaki, Y., Hisatake, K., Fukuda, A., Mizumoto, K.
    • Journal Title

      Seikagaku 76

      Pages: 855-855

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14580630
  • [Journal Article] Overexpression of CR/periphilin downregulates Cdc7 expression and in duces S-phase arrest.2004

    • Author(s)
      Kurita, M., Suzuki, H., Masai, H., Mizumoto, K., Ogata, E., Nishimoto, I., Aiso, S. & Matsuoka, M.
    • Journal Title

      Biochem. Bwphys. Res. Commun. 324

      Pages: 554-561

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14035104
  • [Journal Article] Overexpression of CR/periphilin downregulates Cdc7 expression and inducesS-phase arrest.2004

    • Author(s)
      Kurita. M., Suzuki, H., Masai, H., Mizumoto. K.. Ogata, E., Nishimoto, I., Aiso, S., Matsuoka, M.
    • Journal Title

      Biochem. Biophys. Res. Commun. 324

      Pages: 554-561

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-14035104
  • [Journal Article] Mulyople domains of the mouse P19 (ARF)tumor suppressor are involved inp53-independent apoptosis.2003

    • Author(s)
      Matsuoka, M., Kurita, M., Sudo, H., Mizumoto. K. Nishimoto, I., Ogata, E.
    • Journal Title

      Biochem. Biophys. Res. Commun. 301

      Pages: 1000-1010

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-14035104
  • [Journal Article] Interaction of cellular tubulin with Sendai virus M orotein regulates transcription of viral genome.2003

    • Author(s)
      Ogino, T., Iwama, M., Ohsawa, Y. & Mizumoto. K.
    • Journal Title

      Biochem. Biophys. Res. Commn. 311

      Pages: 283-293

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14035104
  • [Journal Article] The role of mRNA capping enzyme in pol II transcription initiation2003

    • Author(s)
      Shibagaki, Y., Nojima, T., Matsui, H., Hisatake, K., Fukuda, A., Mizumoto, K.
    • Journal Title

      The New Frontier of RNA Science RNA 2003 Kyoto Abstract

      Pages: 175-175

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14580630
  • [Journal Article] pl9ARF-induced p53-independent apoptosis largely occurs through BAX.2003

    • Author(s)
      Suzuki, H., Kurita, M., Mizumoto. K., Nishimoto, I., Ogata, E., Matsuoka, M.
    • Journal Title

      Biochem. Biophys. Res. Commun. 312

      Pages: 1273-1277

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-14035104
  • [Journal Article] Interaction of cellular tubulin with Sendai virus M protein regulatestranscription of viral genome.2003

    • Author(s)
      Ogino, T., Iwama, M., Ohsawa, Y., Mizumoto, K.
    • Journal Title

      Biochem. Biophys. Res. Comm. n 311

      Pages: 283-293

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-14035104
  • [Journal Article] pl9ARF-induced p53-independent apoptosis largely occurs through BAX.2003

    • Author(s)
      Suzuki, H., Kurita, M., Mizumoto. K.. Nishimoto. I., Ogata, E. & Matsuoka, M.
    • Journal Title

      Biochem. Biophys. Res. Commun. 312

      Pages: 1273-1277

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14035104
  • [Journal Article] The role of mRNA capping enzyme in pol II transcription initiation2003

    • Author(s)
      Shibagaki, Y., Nojima, T., Hisatake, K., Fukuda, A., Mizumoto, K.
    • Journal Title

      Seikagaku 75

      Pages: 939-939

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14580630
  • [Journal Article] Mulyople domains of the mouse PI 9 (ARF) tumor suppressor are involved in p53-independent apoptosis.2003

    • Author(s)
      Matsuoka, M., Kurita, M., Sudo, H., Mizumoto. K., Nishimoto. I., Ogata, E.
    • Journal Title

      Biochem. Biophys. Res. Commun. 301

      Pages: 1000-1010

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14035104
  • [Journal Article] Minimum molecular architectures for transcription and replication of the influenza virus.2002

    • Author(s)
      Honda, A., Mizumoto. K. & Ishihama, A.
    • Journal Title

      Proc. Nail. Acad. Sci. USA 99

      Pages: 13166-13171

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14035104
  • [Journal Article] Involvement of mRNA capping enzyme in pol II initiation complex2002

    • Author(s)
      Shibagaki, Y., Hisatake, K., Fukuda, A., Fukamachi, N., Tsukamoto, T., Mizumoto, K.
    • Journal Title

      Seikagaku 74

      Pages: 1001-1001

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14580630
  • [Journal Article] Minimum molecular architectures for transcription and replication of the influenza virus.2002

    • Author(s)
      Honda, A., Mizumoto. K. &Ishihama, A.
    • Journal Title

      Proc. Natl. Acad. Sci. USA 99

      Pages: 13166-13171

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-14035104
  • [Journal Article] Differential effect of ik3-l/Cables on p53- and p73-induced cell death.2002

    • Author(s)
      Tsuji, K., Mizumoto. K., Yamochi, T., Nishimoto, I., Matsuoka, M.
    • Journal Title

      J. Biol. Chem. 277

      Pages: 2951-2957

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14035104
  • [Journal Article] Interaction of S-adenosylhomocysteine hydrolase of Xenopus laevis withmRNA(guanine-7-)methyltransferase : Implication on its nuclear compartmentalisation and on cap methvlation of hnRNA.2002

    • Author(s)
      Radomski, N., Barreto, G., Kaufmann, C, Yokosuka, J., Mizumoto, K. & Dreyer, C.
    • Journal Title

      Biochem. Biophys. Acta 1590

      Pages: 93-102

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-14035104
  • [Journal Article] Differential effect of ik3-I/Cables on p53- and p73-induced cell death.2002

    • Author(s)
      Tsuji, K., Mizumoto. K, Yamochi, T., Nishimoto, I., Matsuoka, M.
    • Journal Title

      J. Biol. Chem. 277

      Pages: 2951-2957

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-14035104
  • [Journal Article] Proteomic analysis of human brain identifies -enolase as a novel autoantigen in Hashimoto's encephalopathy.2002

    • Author(s)
      Ochi, H., Horiuchi, I., Araki, N., Toda, T., Araki, T., Sato, K., Murai, H., Osoegawa, M., Yamada, T., Okamura, K., Ogino, T., Mizumoto. K., Yamashita, H., Saya, H., J. Kira
    • Journal Title

      FEBS Lett. 528

      Pages: 197-202

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14035104
  • [Journal Article] Interaction of S-adenosylhomocysteine hydrolase of Xenopus laevis with mRNA(guanine-7-)methyltransferase: Implication on its nuclear compartmentalisation and on cap methylation of hnRNA.2002

    • Author(s)
      Radomski, N., Barreto, G., Kaufmann, C, Yokosuka, J., Mizumoto. K. & Dreyer, C.
    • Journal Title

      Biochem. Biophys. Acta 1590

      Pages: 93-102

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14035104
  • [Journal Article] p53-independent apoptosis is induced by the pl9ARF tumor suppressor.2002

    • Author(s)
      Tsuji, K., Mizumoto. K., Sudo, H., Kouyama, K., Ogata, E. & Matsuoka, M.
    • Journal Title

      Biochem. Biophys. Res. Commun. 295

      Pages: 621-629

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14035104
  • [Journal Article] Proteomic analysis of human brain identifies -enolase as a novel autoantigen in Hashimoto's encephalopathy.2002

    • Author(s)
      Ochi, H., Horiuchi, I., Araki, N., Toda, T., Araki, T., Sato, K., Murai, H., Osoegawa, M., Yamada, T., Okamura, K., Ogino, T., Mizumoto. K., Yamashita, H., Saya, H., J. Kira
    • Journal Title

      FEBS Lett 528

      Pages: 197-202

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-14035104
  • [Journal Article] p53-independent apoptosis is induced by the pl9ARF tumor suppressor.2002

    • Author(s)
      Tsuji, K., Mizumoto. K., Sudo, H., Kouyama, K., Ogata, E., Matsuoka, M.
    • Journal Title

      Biochem. Biophys. Res. Commun 295

      Pages: 621-629

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-14035104
  • [Presentation] 新規RNA 5'-トリホスファターゼ阻害物質MI481-42F6 A, B, CおよびDに関する研究2014

    • Author(s)
      梅北まや、五十嵐雅之、澤竜一、山崎学、林千草、波多野和樹、藤原俊伸、水本清久、野本明男
    • Organizer
      日本農芸化学会2014年度大会
    • Place of Presentation
      明治大学生田キャンパス(川崎市)
    • Year and Date
      2014-03-30
    • Data Source
      KAKENHI-PROJECT-24659139
  • [Presentation] インフルエンザウイルスRNAポリメラーゼがもつキャップ依存エンドヌクレアーゼ活性を阻害する低分子化合物の探索2013

    • Author(s)
      山崎学、滝沢直己、藤原俊伸、水本清久、野本明男
    • Organizer
      第61回日本ウイルス学会学術集会
    • Place of Presentation
      神戸国際会議場(神戸市)
    • Year and Date
      2013-11-11
    • Data Source
      KAKENHI-PROJECT-24659139
  • [Presentation] Analysis of capped RNA by boronate affinity PAGE2006

    • Author(s)
      Yoshio Shibagaki, Kiyohisa Mizumoto
    • Organizer
      20th IUBMB International Congress of Biochemistry and Morecular Biology and nth FAOBMB Congress
    • Place of Presentation
      Kyoto, Japan
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14035104
  • [Presentation] The mechanism of capping of RNA polymerase II transcripts - The timing of cap formation2006

    • Author(s)
      Tetsuro Komatsu, Yoshio Shibagaki, Kiyohisa Mizumoto
    • Organizer
      20th IUBMB International Congress of Biochemistry andMorecular Biology and nth FAOBMB Congress
    • Place of Presentation
      Kyoto, Japan
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14035104
  • [Presentation] Analysis of capped RNA by boronate affinity PAGE2006

    • Author(s)
      Yoshio Shibagaki, Kiyohisa Mizumoto
    • Organizer
      20th IUBMB International Congress of Biochemistry and Morecular Biology and 11th FAOBMB Congress
    • Place of Presentation
      Kyoto
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14035104
  • [Presentation] Characterizaation of cap-dependent endonuclease activily associated with influenza vims RNA polymerase.- the comparison of type A and type B viruses2006

    • Author(s)
      Chitose Wakai, Takatoshi Saito, Minako Iwama, Yujiro Suzuki, Kiyohisa Mizumoto
    • Organizer
      20th IUBMB International Congress of Biochemistry and Morecular Biology and 11th FAOBMB Congress
    • Place of Presentation
      Kyoto
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14035104
  • [Presentation] The mechanism of capping of RNA polymerase II transcripts - The timing of cap formation2006

    • Author(s)
      Tetsuro Komatsu, Yoshio Shibagaki, Kiyohisa Mizumoto
    • Organizer
      20th IUBMB International Congress of Biochemistry and Morecular Biology and 11th FAOBMB Congress
    • Place of Presentation
      Kyoto
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14035104
  • [Presentation] Characterizaation of cap-dependent endonuclease activity associated with influenzavirus RNA polymerase - the comparison of type A and type B viruses2006

    • Author(s)
      Chitose Wakai, Takatoshi Saito, MinakoIwama, Yujiro Suzuki, Kiyohisa Mizumoto
    • Organizer
      20th IUBMB International Congress of Biochemistry and Morecular Biology and l 1th FAOBMB Congress
    • Place of Presentation
      Kyoto, Japan
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14035104
  • [Presentation] Functional analysis of helicase and kinase activities of TFIIH2005

    • Author(s)
      Hisatake K, Fukuda A, Shibagaki Y, Nakafuo T, Shimada M, Mizumoto K, Nogi Y
    • Organizer
      The 26th Annual Meeting The Molecular Biology Society of Japan, Symposium
    • Place of Presentation
      Kobe
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14035104
  • [Presentation] Catalytic Properties of Capped RNA Endonuclease Associated with InfluenzaVirus RNA Polym erase - The Comparison of Type A and Type B Viruses2005

    • Author(s)
      Wakai C, Saito T, Iwama M, Suzuki Y, Mizumoto K
    • Organizer
      XIIIth International Congress of Virology
    • Place of Presentation
      San Francisco, USA
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14035104
  • [Presentation] Catalytic Properties of Capped RNA Endonuclease Associated with Influenza Virus RNA Polymerase - The Comparison of Type A and Type B Viruses2005

    • Author(s)
      Wakai C, Saito T, Iwama M, Suzuki Y, Mizumoto K
    • Organizer
      XIIIth International Congress of Virology
    • Place of Presentation
      San Francisco
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14035104
  • [Presentation] Analysis of protein factors required for in vitro transcription of Sendai virus genome.2004

    • Author(s)
      Mizumoto K
    • Organizer
      The 25th Annual Meeting The molecular Biology Society of Japan, Workshop
    • Place of Presentation
      Yokohama
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14035104
  • [Presentation] センダイウイルスRNA依存RNAポリメラーゼ(Lタンパク質)はウイルス特異的のmRNAのキャップをメチル化する2003

    • Author(s)
      荻野朝朗, 小林正樹, 岩間美奈子, 水本清久
    • Organizer
      国際シンポジウム「RNA研究のフロンティア」
    • Place of Presentation
      Kyoto, Japan
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14035104
  • [Presentation] 転写初期反応におけるRNA polymerase II によるmRNAキャップ化酵素の役割2003

    • Author(s)
      柴垣芳夫, 野島孝之, 松井博紀, 久武幸司, 福田綾, 水本清久
    • Organizer
      国際シンポジウム「RNA研究のフロンティア」
    • Place of Presentation
      Kyoto, Japan
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14035104
  • [Presentation] Sendai virus RNA-dependent RNA polymerase (L protein) catalyzes cap methylation of virus-specific mRNA2003

    • Author(s)
      Ogino T, Kobayashi M, Iwama M, Mizumoto K.
    • Organizer
      RNA2003 Kyoto
    • Place of Presentation
      Kyoto
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14035104
  • [Presentation] THIIHのヘリガーゼとキナーゼ活性の機能解析2003

    • Author(s)
      久武幸司, 福田綾, 柴垣芳夫, 中太智義, 嶋田美穂, 水本清久, 禾康壽
    • Organizer
      第26回日本分子生物学会年会シンポジウム
    • Place of Presentation
      神戸、日本
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14035104
  • [Presentation] インフルエンザウイルスRNAポリメラーゼの活性と特異性の制御2003

    • Author(s)
      本田文江, 岡本拓人, 水本清久, 清水一史, 宮尾憲孝, 石浜明
    • Organizer
      日本ウイルス学会第51回学術集会・総会ワークシヨップ
    • Place of Presentation
      京都、日本
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14035104
  • [Presentation] Involvement of mRNA capping enzyme in transcription initiation by RNA polymerase II2003

    • Author(s)
      Shibagaki Y, Nojima T, Matsui H, Hisatake K, Fukuda A, Mizumoto K.
    • Organizer
      RNA2003 Kyoto
    • Place of Presentation
      Kyoto
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14035104
  • [Presentation] Regulation of activities and specificity of influenza vims RNA polymerase2002

    • Author(s)
      Honda F, Okamoto T, Mizumoto K, Shimizu K, Miyao K, Ishihama A.
    • Organizer
      The 51st Annual Meeting of The Japanese Society for Virology
    • Place of Presentation
      Kyoto
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14035104
  • [Presentation] センダイウイルスゲノムの転写に関与する宿主因子群の解析2002

    • Author(s)
      水本清久
    • Organizer
      第25回日本分子生物学会年会フーグショップ
    • Place of Presentation
      横浜、日本
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14035104
  • [Presentation] 新規RNA5’-トリホスファターゼ阻害物質MI481-42F6 A,B,CおよびDに関する研究

    • Author(s)
      梅北まや、五十嵐雅之、澤竜一、山崎学、林千草、波多野和樹、藤原俊伸、水本清久、野本明男
    • Organizer
      日本農芸化学会2014年度大会
    • Place of Presentation
      明治大学生田キャンパス(川崎市)
    • Data Source
      KAKENHI-PROJECT-24659139
  • [Presentation] インフルエンザウイルスRNAポリメラーゼがもつキャップ依存エンドヌクレアーゼ活性を阻害する低分子化合物の探索

    • Author(s)
      山崎学、滝沢直己、藤原俊伸、水本清久、野本明男
    • Organizer
      第61回日本ウイルス学会学術集会
    • Place of Presentation
      神戸国際会議場(神戸市)
    • Data Source
      KAKENHI-PROJECT-24659139
  • 1.  野本 明男 (70112670)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 1 results
  • 2.  石浜 明 (80019869)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  TSUKAMOTO Toshihiko (10236862)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  永井 美之 (20022874)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  永田 恭介 (40180492)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  TANAKA Michiko (60114550)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  OHSHIMA Yasumi (90037606)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  IWAMA Minako (10223421)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  SHIBAGAKI Yoshio (90235565)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 10.  岡田 吉美 (30011703)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  YAMASAKI Manabu (50442570)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 12.  TAKIZAWA Naoki (50448502)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 13.  YAMAGISHI Masahiro (00220252)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  OGINO Tomoaki (80312213)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  INADA Toshifumi (40242812)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  HISATAKE Koji (70271236)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 17.  AIBA Hiroji (20025662)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  HANDA Hiroshi (80107432)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  ISHII Shunsuke (00124785)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  NAKAMURA Yoshikazu (40114590)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  SHIMIZU Kazufumi (50004677)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  SUGANO Junjo (80192756)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  吉田 光昭 (80012607)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  豊島 久真男 (90029760)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  吉倉 廣 (60012754)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  豊田 春香 (10197973)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  田代 真人 (90111343)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  岩崎 憲太郎 (90009986)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  志村 令郎 (60025426)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  重定 勝哉 (40009626)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  山尾 文明 (10158074)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  鈴木 義昭 (50132733)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  有賀 寛芳 (20143505)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  渋田 博 (70012721)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  藤原 俊伸
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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