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TAKIZAWA Haruhiko  滝澤 温彦

ORCIDConnect your ORCID iD *help
… Alternative Names

滝沢 温彦  タキサワ ハルヒコ

滝澤 温彦  タキサワ ハルヒコ

高澤 温彦  タキサワ ハルヒコ

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Researcher Number 60154944
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2007 – 2009: 大阪大学, 大学院・理学研究科, 教授
2004 – 2006: 大阪大学, 理学研究科, 教授
2005: Osaka University, Graduate School of Science, Department of Biological Sciences, Professor, 大学院理学研究科, 教授
1999 – 2003: 大阪大学, 大学院・理学研究科, 教授
1997 – 1999: 大阪大学, 大学院・理学研究科, 助教授 … More
1996: 大阪大学, 大学院・理学研究科, 助手
1994 – 1995: 大阪大学, 理学部, 助手
1992: 大阪大学, 理学部, 助手
1988 – 1989: 大阪大学, 理学部, 助手 Less
Review Section/Research Field
Principal Investigator
代謝生物化学 / Molecular biology / Biological Sciences
Except Principal Investigator
Biological Sciences / Molecular biology
Keywords
Principal Investigator
MCM蛋白質 / MCM / DNA複製 / 分泌反応 / 分泌顆粒 / 血小板 / 複製ライセンス因子 / 複製開始複合体 / 無細胞複製系 / DNA replication … More / Cdc45 / GINS / カルシウム / 構成的タンパク質リン酸化 / タンパク質リン酸化酵素 / アフリカツメガエル卵 / 無細胞DNA複製系 / DNA複製開始機構 / 核構造 / DNA複製開始許可因子 / 真核生物DNA複製 / ツメガエル卵 / Zn フィンガー / ツメガエル / 核輸送 / カルシウムシグナル / セロトニン分泌 / マイクロフィラメント / 染色体複製 / 複製開始領域 / 複製開始装置 / 複製開始制御 / DNA複製関連遺伝子 / ORC / CDC7 / CDC45 / 染色体 / DNAポリメラーゼ / 複製必須配列 / Cdc7-Dbf4キナーゼ / P1蛋白質 / DNA複製遺伝子の発現制御 / 転写制御因子間相互作用 / DNA複製開始領域 / DNA複製開始蛋白質 / P1ファミリー蛋白質 / CDC7類似キナーゼ / 複製関連遺伝子 / 転写調節因子 / DREF / chromosome replication / replication origin / replication initiation apparatus / regulation of initiation / replication-related gene / クロマチン / MCMタンパク質 / Cdc45タンパク質 / アフリカツメガエル卵抽出液 / クロマチン結合蛋白質 / ORC蛋白質 / ヒストン / DNA複製開始 / P1ファミリー / ヒストンH3 / アフリカツメガエル卵無細胞系 / chromatin / Xenopus egg extract / Cell free replication system / レプリソーム / ChIP-chip法 / 複製チェックポイント制御機構 / DNA複製因子 / 複製ライセンス化 / 複製チェックポイント / RecQ4 / Sld2 / Tof1 / Tim1 / Csm3 / Tipin / 複製フォーク / Mrc1 / geminin / Dpb11 / Cut5 / TopBP1 / DNA複製制御 / S期CDK / アフリカツメガエル / DNAヘリカーゼ / Mcmタンパク質 / Initiation complex / rep liso me / ChIP-chip method / Replication checkpoint … More
Except Principal Investigator
DNA複製 / 複製蛋白 / 複製起点 / 染色体分配 / 細胞分裂 / ライセンス因子 / チェックポイント / 複製開始複合体 / 細胞周期 / 複製チェックポイント / 染色体 / リン酸化制御 / 複製開始点 / 複製開始蛋白 / 複製装置 / 複製開始の調節 / SeqA / DnaA / 複製開始 / DNAヘリカーゼ / 複製開始前複合体 / リン酸化 / 複製開始点認識 / チェックポイント制御 / 細胞周期制御 / 複製開始点認識複合体 / クロマチン / セントロメア / テロメア / MCMヘリカーゼ / 分裂酵母 / ヘテロクロマチン / クロマチン構造 / 複製チェッポイント / 遺伝学 / 核酸 / ゲノム / 蛋白質 / 微生物 Less
  • Research Projects

    (14 results)
  • Research Products

    (36 results)
  • Co-Researchers

    (15 People)
  •  Studies on molecular assembly of replication proteins and regulation of their functions in initiation of chromosome DNA replication

    • Principal Investigator
      MASUKATA Hisao
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  Regulation of initiation and elongation stages of DNA replicationPrincipal Investigator

    • Principal Investigator
      TAKISAWA Haruhiko
    • Project Period (FY)
      2001 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  Mcm蛋白質ならびにMcmと相互作用する蛋白質複合体による複製モニター機構

    • Principal Investigator
      升方 久夫
    • Project Period (FY)
      1999 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  細胞複製装置:染色体の複製・分配機構

    • Principal Investigator
      平賀 壮太 (平賀 壯太 / 平賀 莊太)
    • Project Period (FY)
      1996 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kumamoto University
  •  Regulation of initiation of chromosome replicationPrincipal Investigator

    • Principal Investigator
      TAKISAWA Haruhiko
    • Project Period (FY)
      1996 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Graduate School of Science, Osaka University
  •  Studies on the factors required for the formation of high-order chromatin structure.Principal Investigator

    • Principal Investigator
      TAKISAWA Haruhiko
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Molecular biology
    • Research Institution
      Osaka University
  •  真核細胞DNA複製ライセンス因子の同定とその機能の解明Principal Investigator

    • Principal Investigator
      滝澤 温彦
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  核構造に依存したDNA複製開始機構Principal Investigator

    • Principal Investigator
      滝澤 温彦
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  細胞複製装置:染色体の複製・分配機構

    • Principal Investigator
      平賀 壯太
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Molecular biology
    • Research Institution
      Kumamoto University
  •  アフリカツメガエル卵無細胞系における核構造に依存したDNA複製開始機構Principal Investigator

    • Principal Investigator
      滝澤 温彦
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  真核生物DNA複製開始許可因子の同定Principal Investigator

    • Principal Investigator
      滝澤 温彦
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  構成的に活性化されているタンパク質リン酸化酵素の深索Principal Investigator

    • Principal Investigator
      滝澤 温彦
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      代謝生物化学
    • Research Institution
      Osaka University
  •  カルシウムイオンによる血小板細胞内顆粒分秘の制御機構Principal Investigator

    • Principal Investigator
      高澤 温彦
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  カルシウムイオンによる血小板細胞内顆粒分泌の制御機構Principal Investigator

    • Principal Investigator
      滝澤 温彦
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University

All 2011 2009 2008 2007 2006 2005 2004 2003

All Journal Article Presentation Book Patent

  • [Book] 生化学事典第4版 (大島泰郎・今堀和友編)2007

    • Author(s)
      滝澤 温彦
    • Total Pages
      1616
    • Publisher
      東京化学同人
    • Data Source
      KAKENHI-PROJECT-17080003
  • [Book] 細胞核のダイナミックス 再構成核におけるDNA複製の解析2004

    • Author(s)
      久保田弓子, 滝澤温彦
    • Total Pages
      12
    • Publisher
      シュプリンガー・フェアラーク東京
    • Data Source
      KAKENHI-PROJECT-13043029
  • [Journal Article] Inter-origin cooperativity of geminin action establishes an all-or-none switch for replication origin licensing.2011

    • Author(s)
      Ode KL, Fujimoto K, Kubota Y, Takisawa H.
    • Journal Title

      Gene Cells. 16

      Pages: 380-396

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17080003
  • [Journal Article] アフリカツメガエル卵抽出液におけるpreRC形成2009

    • Author(s)
      大出晃士、滝澤温彦
    • Journal Title

      蛋白質核酸酵素

      Volume: 54(4) Pages: 334-342

    • Data Source
      KAKENHI-PROJECT-17080003
  • [Journal Article] An auxin-based degron system for the rapid depletion of proteins in animal cells and yeast.2009

    • Author(s)
      Nishimura K, Fukagawa T, Takisawa H., Kakimoto T, Kanemaki M
    • Journal Title

      Nature Methods 12

      Pages: 917-922

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17080003
  • [Journal Article] An auxin-based degron system for the rapid depletion of proteins in animal cells and yeast.2009

    • Author(s)
      Nishimura, K., Takisawa, H., et. al.
    • Journal Title

      Nature Methods

      Volume: 12 Pages: 917-922

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17080003
  • [Journal Article] Replisome progression complex links DNA replication to sister chromatid cohesion in Xenopus egg extracts.2009

    • Author(s)
      Tanaka H, Kubota Y, Tsujimura T, Kumano M, Masai H, Takisawa H.
    • Journal Title

      Genes Cells 14

      Pages: 949-963

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17080003
  • [Journal Article] Replisome progression complex links DNA replication to sister chromatid cohesion in Xenopus egg extracts.2009

    • Author(s)
      Tanaka, H., Takisawa, H., et.al.
    • Journal Title

      Genes Cells

      Volume: 14 Pages: 949-963

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17080003
  • [Journal Article] アフリカツメガエル卵抽出液におけるpreRC形成.蛋白質核酸酵素-増刊号2009

    • Author(s)
      大出晃士,滝澤温彦
    • Journal Title

      染色体サイクル(共立出版) 54巻4号

      Pages: 334-342

    • Data Source
      KAKENHI-PROJECT-17080003
  • [Journal Article] 複製フォーク形成複合体の染色体サイクルにおける働き2008

    • Author(s)
      鐘巻将人,久保田弓子,滝澤温彦
    • Journal Title

      細胞工学(秀潤社) 27巻10号

      Pages: 992-997

    • Data Source
      KAKENHI-PROJECT-17080003
  • [Journal Article] Regulation of Replication Licensing by Acetyltransferase Hbol.2006

    • Author(s)
      Iizuka, M., Matsui, T., Takisawa, H., Smith, M.M.
    • Journal Title

      Mol. Cell. Biol. 26(3)

      Pages: 1098-1108

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13043029
  • [Journal Article] The N-terminal noncatalytic region of Xenopus RecQ4 is required for chromatin binding of DNA polymerase a in the initiation of DNA replication.2006

    • Author(s)
      Matsuno, K., Kumano, M., Kubota, Y., Hashimoto, Y., Takisawa, H.
    • Journal Title

      Mol. Cell. Biol. 26(13)

      Pages: 4843-4852

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13043029
  • [Journal Article] Localization of MCM2-7, Cdc45, and GINS to the Site of DNA Unwinding during Eukaryotic DNA.2006

    • Author(s)
      Pacek, M., Tutter, A.V., Kubota, Y., Takisawa, H., Walter, J.C.
    • Journal Title

      Mol. Cell 21(4)

      Pages: 581-587

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13043029
  • [Journal Article] The phosphorylated C-terminal domain of Xenopus Cut5 directly mediates ATR-dependent activation of Chkl2006

    • Author(s)
      Hashimoto, Y., Tsujimura, T.Sugino, A., Takisawa, H.
    • Journal Title

      Genes Cells 11(9)

      Pages: 993-1007

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13043029
  • [Journal Article] The N-terminal noncatalytic region of Xenopus RecQ4 is required for chromatin binding of DNA polymerase a in the initiation of DNA replication.2006

    • Author(s)
      Matsuno K, Kumano M, Kubota Y, Hashimoto Y, Takisawa H
    • Journal Title

      Mol.Cell.Biol. 26

      Pages: 4843-4852

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17080003
  • [Journal Article] Localization of MCM2-7, Cdc45 and GINS to the site of DNA unwinding during eukaryotic DNA replication.2006

    • Author(s)
      Pacek M, Tutter AV, Kubota Y, Takisawa H., Walter JC
    • Journal Title

      Mol.Cell 21

      Pages: 581-587

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17080003
  • [Journal Article] The phosphorylated C-terminal domain of Xenopus Cut5 directly mediates ATR-dependent activation of Chk1.2006

    • Author(s)
      Hashimoto Y, Tsujimura T, Sugino A, Takisawa H.
    • Journal Title

      Genes Cells 11

      Pages: 993-1007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17080003
  • [Journal Article] Intrinsic nuclear import activity of geminin is essential to prevent re-initiation of DNA replication in Xenopus eggs.2005

    • Author(s)
      Yoshida K, Takisawa H., Kubota Y
    • Journal Title

      Genes Cells 10

      Pages: 63-73

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17080003
  • [Journal Article] Intrinsic nuclear import activity of geminin is essential to prevent re-initiation of DNA replication in Xenopus eggs.2005

    • Author(s)
      Yoshida, K., Takisawa, H., Kubota, Y.
    • Journal Title

      Genes Cells 10(1)

      Pages: 63-73

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13043029
  • [Journal Article] DNA複製装置-レプリソームの形成・維持を制御する機構2005

    • Author(s)
      久保田弓子,橋本吉民,滝澤温彦
    • Journal Title

      化学と生物(日本農芸化学会) 43巻8号

      Pages: 519-527

    • NAID

      10019044376

    • Data Source
      KAKENHI-PROJECT-17080003
  • [Journal Article] DNA複製のライセンス化制御2005

    • Author(s)
      吉田和真,滝澤温彦,久保田弓子
    • Journal Title

      実験医学(羊土社) 23巻9号

      Pages: 1340-1346

    • Data Source
      KAKENHI-PROJECT-17080003
  • [Journal Article] DNA複製装置、レプリソームの形成・維持を制御する機構2005

    • Author(s)
      滝澤温彦, 橋本吉民, 久保田弓子
    • Journal Title

      化学と生物 43(8)

      Pages: 61-67

    • NAID

      10019044376

    • Data Source
      KAKENHI-PROJECT-17080003
  • [Journal Article] Xenopus Cut5 is essential for a CDK-dependent process in the initiation of DNA replication.2003

    • Author(s)
      Hashimoto, Y., Takisawa, H.
    • Journal Title

      EMBOJ. 22(10)

      Pages: 2526-2535

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13043029
  • [Journal Article] A novel ring-like complex of Xenopus proteins essential for the initiation of DNA replication.2003

    • Author(s)
      Kubota' Y., Takase' Y., Komori, Y., Hashimoto, Y., Arata, T., Kamimura, Y., Araki, H., Takisawa, H.
    • Journal Title

      Genes & Dev. 17(9)

      Pages: 1141-1152

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13043029
  • [Journal Article] CDK-and Cdc45-dependent priming of the MCM complex on chromatin during S-phase in Xenopus egg extracts.2003

    • Author(s)
      Masuda, T., Mimura, S., Takisawa, H.
    • Journal Title

      Genes Cells 8(2)

      Pages: 145-161

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13043029
  • [Patent] 非植物生物におけるオーキシン誘導的蛋白質分解系2007

    • Inventor(s)
      鐘巻将人、西村浩平、柿本辰男、滝澤温彦
    • Industrial Property Rights Holder
      鐘巻将人、西村浩平、柿本辰男、滝澤温彦
    • Patent Publication Number
      2008-187958
    • Filing Date
      2007
    • Data Source
      KAKENHI-PROJECT-17080003
  • [Presentation] Replisome formation and sister chromatid cohesion in Xenopus egg extracts.2009

    • Author(s)
      H.Takisawa
    • Organizer
      Switzerlan-Japan joint meeting on Chromosome Dynamics and Genome Stability
    • Place of Presentation
      Villars-sur-Ollons, Switzerland(招待講演)
    • Data Source
      KAKENHI-PROJECT-17080003
  • [Presentation] Exploring factors involving maintenance and re-start of the stalled forks by using a novel method to induce rapid degradation in budding yeast.2009

    • Author(s)
      K.Nishimura, H.Takisawa
    • Organizer
      Eukaryotic DNA replication and genome maintenance
    • Place of Presentation
      Cold Spring Harbor, NY, USA
    • Data Source
      KAKENHI-PROJECT-17080003
  • [Presentation] CDK activity is required for the RecQ4-dependent process of the initiation of DNA replication in Xenopus egg extracts.2009

    • Author(s)
      Y.Kubota, H.Takisawa
    • Organizer
      Eukaryotic DNA replication and genome maintenance
    • Place of Presentation
      Cold Spring Harbor, NY, USA(招待講演)
    • Data Source
      KAKENHI-PROJECT-17080003
  • [Presentation] Coupling of initiation of DNA replication and establishment of sister chromatid cohesion in Xenopus egg extracts.2009

    • Author(s)
      H.Takisawa
    • Organizer
      ASBMB symposium, Experimental Biology, 2009,(招待講演)
    • Place of Presentation
      New Orleans, USA.
    • Data Source
      KAKENHI-PROJECT-17080003
  • [Presentation] Replisome formation and sister chromatid cohesion in Xenopus egg extracts.2009

    • Author(s)
      H.Takisawa
    • Organizer
      Switzerlan-Japan joint meeting on Chromosome Dynamics and Genome Stability,(招待講演)
    • Place of Presentation
      Villars-sur-Ollons, Switzerland.
    • Data Source
      KAKENHI-PROJECT-17080003
  • [Presentation] Geminin inhibits origin licensing through a novel feedback pathway.2009

    • Author(s)
      K.Ode, H.Takisawa
    • Organizer
      Eukaryotic DNA replication and genome maintenance
    • Place of Presentation
      Cold Spring Harbor, NY, USA
    • Data Source
      KAKENHI-PROJECT-17080003
  • [Presentation] ヒストンシャペロンFACTは複製伸長反応において複製フォークの安定化に関わる2009

    • Author(s)
      中村淳児、滝澤温彦
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜(パシフィコ横浜、神奈川県)(招待講演)
    • Data Source
      KAKENHI-PROJECT-17080003
  • [Presentation] Coupling of initiation of DNA replication and establishment of sister chromatid cohesion in Xenopus egg extracts.2009

    • Author(s)
      H.Takisawa
    • Organizer
      ASBMB symposium, Experimental Biology 2009
    • Place of Presentation
      New Orleans, USA(招待講演)
    • Data Source
      KAKENHI-PROJECT-17080003
  • [Presentation] Xenopus AND-1 and. Tim-Tipin, components of replication fork progression complex, are required for establishment of sister chromatid cohesion2008

    • Author(s)
      H. Takisawa
    • Organizer
      The 6^<th> 3R Symposium
    • Place of Presentation
      つま恋、静岡
    • Data Source
      KAKENHI-PROJECT-17080003
  • [Presentation] Xenopus卵抽出液を用いた染色体複製装置の分子構築解析2007

    • Author(s)
      滝澤 温彦
    • Organizer
      第30回日本分子生物学会年会/第80回日本生化学会大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-17080003
  • 1.  MASUKATA Hisao (00199689)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 2.  MATSUKAGE Akio (90019571)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  平賀 壯太 (40027321)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  ISHIMI Yukio (80159772)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  SHIRAHIGE Katsuhiko (90273854)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  杉野 明雄 (90231737)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  MASAI Hisao (40229349)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  荻原 哲 (30169221)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  吉田 松年 (70090420)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  伊藤 嘉明 (80004612)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  吉川 寛 (70019876)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  柳田 充弘 (80025428)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  岡崎 恒子 (10022584)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  片山 勉 (70264059)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  SHINOMIYA Tomoyuki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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