TAKIZAWA Haruhiko 滝澤温彦

… Alternative Names

滝沢温彦タキサワハルヒコ

滝澤温彦タキサワハルヒコ

高澤温彦タキサワハルヒコ

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Researcher Number	60154944
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Affiliation (based on the past Project Information) *help	2007 – 2009: 大阪大学, 大学院・理学研究科, 教授 2004 – 2006: 大阪大学, 理学研究科, 教授 2005: Osaka University, Graduate School of Science, Department of Biological Sciences, Professor, 大学院理学研究科, 教授 1999 – 2003: 大阪大学, 大学院・理学研究科, 教授 1997 – 1999: 大阪大学, 大学院・理学研究科, 助教授 … More 1996: 大阪大学, 大学院・理学研究科, 助手 1994 – 1995: 大阪大学, 理学部, 助手 1992: 大阪大学, 理学部, 助手 1988 – 1989: 大阪大学, 理学部, 助手 Less
Review Section/Research Field	Principal Investigator 代謝生物化学 / Molecular biology / Biological Sciences Except Principal Investigator Biological Sciences / Molecular biology
Keywords	Principal Investigator MCM蛋白質 / MCM / DNA複製 / 分泌反応 / 分泌顆粒 / 血小板 / 複製ライセンス因子 / 複製開始複合体 / 無細胞複製系 / DNA replication … More / Cdc45 / GINS / カルシウム / 構成的タンパク質リン酸化 / タンパク質リン酸化酵素 / アフリカツメガエル卵 / 無細胞DNA複製系 / DNA複製開始機構 / 核構造 / DNA複製開始許可因子 / 真核生物DNA複製 / ツメガエル卵 / Zn フィンガー / ツメガエル / 核輸送 / カルシウムシグナル / セロトニン分泌 / マイクロフィラメント / 染色体複製 / 複製開始領域 / 複製開始装置 / 複製開始制御 / DNA複製関連遺伝子 / ORC / CDC7 / CDC45 / 染色体 / DNAポリメラーゼ / 複製必須配列 / Cdc7-Dbf4キナーゼ / P1蛋白質 / DNA複製遺伝子の発現制御 / 転写制御因子間相互作用 / DNA複製開始領域 / DNA複製開始蛋白質 / P1ファミリー蛋白質 / CDC7類似キナーゼ / 複製関連遺伝子 / 転写調節因子 / DREF / chromosome replication / replication origin / replication initiation apparatus / regulation of initiation / replication-related gene / クロマチン / MCMタンパク質 / Cdc45タンパク質 / アフリカツメガエル卵抽出液 / クロマチン結合蛋白質 / ORC蛋白質 / ヒストン / DNA複製開始 / P1ファミリー / ヒストンH3 / アフリカツメガエル卵無細胞系 / chromatin / Xenopus egg extract / Cell free replication system / レプリソーム / ChIP-chip法 / 複製チェックポイント制御機構 / DNA複製因子 / 複製ライセンス化 / 複製チェックポイント / RecQ4 / Sld2 / Tof1 / Tim1 / Csm3 / Tipin / 複製フォーク / Mrc1 / geminin / Dpb11 / Cut5 / TopBP1 / DNA複製制御 / S期CDK / アフリカツメガエル / DNAヘリカーゼ / Mcmタンパク質 / Initiation complex / rep liso me / ChIP-chip method / Replication checkpoint … More Except Principal Investigator DNA複製 / 複製蛋白 / 複製起点 / 染色体分配 / 細胞分裂 / ライセンス因子 / チェックポイント / 複製開始複合体 / 細胞周期 / 複製チェックポイント / 染色体 / リン酸化制御 / 複製開始点 / 複製開始蛋白 / 複製装置 / 複製開始の調節 / SeqA / DnaA / 複製開始 / DNAヘリカーゼ / 複製開始前複合体 / リン酸化 / 複製開始点認識 / チェックポイント制御 / 細胞周期制御 / 複製開始点認識複合体 / クロマチン / セントロメア / テロメア / MCMヘリカーゼ / 分裂酵母 / ヘテロクロマチン / クロマチン構造 / 複製チェッポイント / 遺伝学 / 核酸 / ゲノム / 蛋白質 / 微生物 Less

Studies on molecular assembly of replication proteins and regulation of their functions in initiation of chromosome DNA replication
- Principal Investigator
  
  MASUKATA Hisao
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Regulation of initiation and elongation stages of DNA replicationPrincipal Investigator
- Principal Investigator
  
  TAKISAWA Haruhiko
- Project Period (FY)
  2001 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Mcm蛋白質ならびにMcmと相互作用する蛋白質複合体による複製モニター機構
- Principal Investigator
  
  升方久夫
- Project Period (FY)
  1999 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
細胞複製装置:染色体の複製・分配機構
- Principal Investigator
  
  平賀壮太 (平賀壯太 / 平賀莊太)
- Project Period (FY)
  1996 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kumamoto University
Regulation of initiation of chromosome replicationPrincipal Investigator
- Principal Investigator
  
  TAKISAWA Haruhiko
- Project Period (FY)
  1996 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Graduate School of Science, Osaka University
Studies on the factors required for the formation of high-order chromatin structure.Principal Investigator
- Principal Investigator
  
  TAKISAWA Haruhiko
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Molecular biology
- Research Institution
  Osaka University
真核細胞DNA複製ライセンス因子の同定とその機能の解明Principal Investigator
- Principal Investigator
  
  滝澤温彦
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
核構造に依存したDNA複製開始機構Principal Investigator
- Principal Investigator
  
  滝澤温彦
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
細胞複製装置:染色体の複製・分配機構
- Principal Investigator
  
  平賀壯太
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  Molecular biology
- Research Institution
  Kumamoto University
アフリカツメガエル卵無細胞系における核構造に依存したDNA複製開始機構Principal Investigator
- Principal Investigator
  
  滝澤温彦
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
真核生物DNA複製開始許可因子の同定Principal Investigator
- Principal Investigator
  
  滝澤温彦
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
構成的に活性化されているタンパク質リン酸化酵素の深索Principal Investigator
- Principal Investigator
  
  滝澤温彦
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  代謝生物化学
- Research Institution
  Osaka University
カルシウムイオンによる血小板細胞内顆粒分秘の制御機構Principal Investigator
- Principal Investigator
  
  高澤温彦
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
カルシウムイオンによる血小板細胞内顆粒分泌の制御機構Principal Investigator
- Principal Investigator
  
  滝澤温彦
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University

All 2011 2009 2008 2007 2006 2005 2004 2003

All Journal Article Presentation Book Patent

[Book] 生化学事典第4版 (大島泰郎・今堀和友編)2007
- Author(s)
  滝澤温彦
- Total Pages
  1616
- Publisher
  東京化学同人
- Data Source
  KAKENHI-PROJECT-17080003
[Book] 細胞核のダイナミックス再構成核におけるDNA複製の解析2004
- Author(s)
  久保田弓子, 滝澤温彦
- Total Pages
  12
- Publisher
  シュプリンガー・フェアラーク東京
- Data Source
  KAKENHI-PROJECT-13043029
[Journal Article] Inter-origin cooperativity of geminin action establishes an all-or-none switch for replication origin licensing.2011
- Author(s)
  Ode KL, Fujimoto K, Kubota Y, Takisawa H.
- Journal Title
  
  Gene Cells. 16
  
  Pages: 380-396
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17080003
[Journal Article] アフリカツメガエル卵抽出液におけるpreRC形成2009
- Author(s)
  大出晃士、滝澤温彦
- Journal Title
  
  蛋白質核酸酵素
  
  Volume: 54(4) Pages: 334-342
- Data Source
  KAKENHI-PROJECT-17080003
[Journal Article] An auxin-based degron system for the rapid depletion of proteins in animal cells and yeast.2009
- Author(s)
  Nishimura K, Fukagawa T, Takisawa H., Kakimoto T, Kanemaki M
- Journal Title
  
  Nature Methods 12
  
  Pages: 917-922
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17080003
[Journal Article] An auxin-based degron system for the rapid depletion of proteins in animal cells and yeast.2009
- Author(s)
  Nishimura, K., Takisawa, H., et. al.
- Journal Title
  
  Nature Methods
  
  Volume: 12 Pages: 917-922
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17080003
[Journal Article] Replisome progression complex links DNA replication to sister chromatid cohesion in Xenopus egg extracts.2009
- Author(s)
  Tanaka H, Kubota Y, Tsujimura T, Kumano M, Masai H, Takisawa H.
- Journal Title
  
  Genes Cells 14
  
  Pages: 949-963
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17080003
[Journal Article] Replisome progression complex links DNA replication to sister chromatid cohesion in Xenopus egg extracts.2009
- Author(s)
  Tanaka, H., Takisawa, H., et.al.
- Journal Title
  
  Genes Cells
  
  Volume: 14 Pages: 949-963
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17080003
[Journal Article] アフリカツメガエル卵抽出液におけるpreRC形成.蛋白質核酸酵素-増刊号2009
- Author(s)
  大出晃士,滝澤温彦
- Journal Title
  
  染色体サイクル(共立出版) 54巻4号
  
  Pages: 334-342
- Data Source
  KAKENHI-PROJECT-17080003
[Journal Article] 複製フォーク形成複合体の染色体サイクルにおける働き2008
- Author(s)
  鐘巻将人,久保田弓子,滝澤温彦
- Journal Title
  
  細胞工学(秀潤社) 27巻10号
  
  Pages: 992-997
- Data Source
  KAKENHI-PROJECT-17080003
[Journal Article] Regulation of Replication Licensing by Acetyltransferase Hbol.2006
- Author(s)
  Iizuka, M., Matsui, T., Takisawa, H., Smith, M.M.
- Journal Title
  
  Mol. Cell. Biol. 26(3)
  
  Pages: 1098-1108
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13043029
[Journal Article] The N-terminal noncatalytic region of Xenopus RecQ4 is required for chromatin binding of DNA polymerase a in the initiation of DNA replication.2006
- Author(s)
  Matsuno, K., Kumano, M., Kubota, Y., Hashimoto, Y., Takisawa, H.
- Journal Title
  
  Mol. Cell. Biol. 26(13)
  
  Pages: 4843-4852
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13043029
[Journal Article] Localization of MCM2-7, Cdc45, and GINS to the Site of DNA Unwinding during Eukaryotic DNA.2006
- Author(s)
  Pacek, M., Tutter, A.V., Kubota, Y., Takisawa, H., Walter, J.C.
- Journal Title
  
  Mol. Cell 21(4)
  
  Pages: 581-587
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13043029
[Journal Article] The phosphorylated C-terminal domain of Xenopus Cut5 directly mediates ATR-dependent activation of Chkl2006
- Author(s)
  Hashimoto, Y., Tsujimura, T.Sugino, A., Takisawa, H.
- Journal Title
  
  Genes Cells 11(9)
  
  Pages: 993-1007
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13043029
[Journal Article] The N-terminal noncatalytic region of Xenopus RecQ4 is required for chromatin binding of DNA polymerase a in the initiation of DNA replication.2006
- Author(s)
  Matsuno K, Kumano M, Kubota Y, Hashimoto Y, Takisawa H
- Journal Title
  
  Mol.Cell.Biol. 26
  
  Pages: 4843-4852
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17080003
[Journal Article] Localization of MCM2-7, Cdc45 and GINS to the site of DNA unwinding during eukaryotic DNA replication.2006
- Author(s)
  Pacek M, Tutter AV, Kubota Y, Takisawa H., Walter JC
- Journal Title
  
  Mol.Cell 21
  
  Pages: 581-587
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17080003
[Journal Article] The phosphorylated C-terminal domain of Xenopus Cut5 directly mediates ATR-dependent activation of Chk1.2006
- Author(s)
  Hashimoto Y, Tsujimura T, Sugino A, Takisawa H.
- Journal Title
  
  Genes Cells 11
  
  Pages: 993-1007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17080003
[Journal Article] Intrinsic nuclear import activity of geminin is essential to prevent re-initiation of DNA replication in Xenopus eggs.2005
- Author(s)
  Yoshida K, Takisawa H., Kubota Y
- Journal Title
  
  Genes Cells 10
  
  Pages: 63-73
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17080003
[Journal Article] Intrinsic nuclear import activity of geminin is essential to prevent re-initiation of DNA replication in Xenopus eggs.2005
- Author(s)
  Yoshida, K., Takisawa, H., Kubota, Y.
- Journal Title
  
  Genes Cells 10(1)
  
  Pages: 63-73
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13043029
[Journal Article] DNA複製装置-レプリソームの形成・維持を制御する機構2005
- Author(s)
  久保田弓子,橋本吉民,滝澤温彦
- Journal Title
  
  化学と生物(日本農芸化学会) 43巻8号
  
  Pages: 519-527
- NAID
  10019044376
- Data Source
  KAKENHI-PROJECT-17080003
[Journal Article] DNA複製のライセンス化制御2005
- Author(s)
  吉田和真,滝澤温彦,久保田弓子
- Journal Title
  
  実験医学(羊土社) 23巻9号
  
  Pages: 1340-1346
- Data Source
  KAKENHI-PROJECT-17080003
[Journal Article] DNA複製装置、レプリソームの形成・維持を制御する機構2005
- Author(s)
  滝澤温彦, 橋本吉民, 久保田弓子
- Journal Title
  
  化学と生物 43(8)
  
  Pages: 61-67
- NAID
  10019044376
- Data Source
  KAKENHI-PROJECT-17080003
[Journal Article] Xenopus Cut5 is essential for a CDK-dependent process in the initiation of DNA replication.2003
- Author(s)
  Hashimoto, Y., Takisawa, H.
- Journal Title
  
  EMBOJ. 22(10)
  
  Pages: 2526-2535
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13043029
[Journal Article] A novel ring-like complex of Xenopus proteins essential for the initiation of DNA replication.2003
- Author(s)
  Kubota' Y., Takase' Y., Komori, Y., Hashimoto, Y., Arata, T., Kamimura, Y., Araki, H., Takisawa, H.
- Journal Title
  
  Genes ＆ Dev. 17(9)
  
  Pages: 1141-1152
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13043029
[Journal Article] CDK-and Cdc45-dependent priming of the MCM complex on chromatin during S-phase in Xenopus egg extracts.2003
- Author(s)
  Masuda, T., Mimura, S., Takisawa, H.
- Journal Title
  
  Genes Cells 8(2)
  
  Pages: 145-161
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13043029
[Patent] 非植物生物におけるオーキシン誘導的蛋白質分解系2007
- Inventor(s)
  鐘巻将人、西村浩平、柿本辰男、滝澤温彦
- Industrial Property Rights Holder
  鐘巻将人、西村浩平、柿本辰男、滝澤温彦
- Patent Publication Number
  2008-187958
- Filing Date
  2007
- Data Source
  KAKENHI-PROJECT-17080003
[Presentation] Replisome formation and sister chromatid cohesion in Xenopus egg extracts.2009
- Author(s)
  H.Takisawa
- Organizer
  Switzerlan-Japan joint meeting on Chromosome Dynamics and Genome Stability
- Place of Presentation
  Villars-sur-Ollons, Switzerland(招待講演)
- Data Source
  KAKENHI-PROJECT-17080003
[Presentation] Exploring factors involving maintenance and re-start of the stalled forks by using a novel method to induce rapid degradation in budding yeast.2009
- Author(s)
  K.Nishimura, H.Takisawa
- Organizer
  Eukaryotic DNA replication and genome maintenance
- Place of Presentation
  Cold Spring Harbor, NY, USA
- Data Source
  KAKENHI-PROJECT-17080003
[Presentation] CDK activity is required for the RecQ4-dependent process of the initiation of DNA replication in Xenopus egg extracts.2009
- Author(s)
  Y.Kubota, H.Takisawa
- Organizer
  Eukaryotic DNA replication and genome maintenance
- Place of Presentation
  Cold Spring Harbor, NY, USA(招待講演)
- Data Source
  KAKENHI-PROJECT-17080003
[Presentation] Coupling of initiation of DNA replication and establishment of sister chromatid cohesion in Xenopus egg extracts.2009
- Author(s)
  H.Takisawa
- Organizer
  ASBMB symposium, Experimental Biology, 2009,(招待講演)
- Place of Presentation
  New Orleans, USA.
- Data Source
  KAKENHI-PROJECT-17080003
[Presentation] Replisome formation and sister chromatid cohesion in Xenopus egg extracts.2009
- Author(s)
  H.Takisawa
- Organizer
  Switzerlan-Japan joint meeting on Chromosome Dynamics and Genome Stability,(招待講演)
- Place of Presentation
  Villars-sur-Ollons, Switzerland.
- Data Source
  KAKENHI-PROJECT-17080003
[Presentation] Geminin inhibits origin licensing through a novel feedback pathway.2009
- Author(s)
  K.Ode, H.Takisawa
- Organizer
  Eukaryotic DNA replication and genome maintenance
- Place of Presentation
  Cold Spring Harbor, NY, USA
- Data Source
  KAKENHI-PROJECT-17080003
[Presentation] ヒストンシャペロンFACTは複製伸長反応において複製フォークの安定化に関わる2009
- Author(s)
  中村淳児、滝澤温彦
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜(パシフィコ横浜、神奈川県)(招待講演)
- Data Source
  KAKENHI-PROJECT-17080003
[Presentation] Coupling of initiation of DNA replication and establishment of sister chromatid cohesion in Xenopus egg extracts.2009
- Author(s)
  H.Takisawa
- Organizer
  ASBMB symposium, Experimental Biology 2009
- Place of Presentation
  New Orleans, USA(招待講演)
- Data Source
  KAKENHI-PROJECT-17080003
[Presentation] Xenopus AND-1 and. Tim-Tipin, components of replication fork progression complex, are required for establishment of sister chromatid cohesion2008
- Author(s)
  H. Takisawa
- Organizer
  The 6^<th> 3R Symposium
- Place of Presentation
  つま恋、静岡
- Data Source
  KAKENHI-PROJECT-17080003
[Presentation] Xenopus卵抽出液を用いた染色体複製装置の分子構築解析2007
- Author(s)
  滝澤温彦
- Organizer
  第30回日本分子生物学会年会/第80回日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-17080003

1. MASUKATA Hisao (00199689)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. MATSUKAGE Akio (90019571)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. 平賀壯太 (40027321)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. ISHIMI Yukio (80159772)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. SHIRAHIGE Katsuhiko (90273854)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 杉野明雄 (90231737)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. MASAI Hisao (40229349)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 荻原哲 (30169221)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 吉田松年 (70090420)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 伊藤嘉明 (80004612)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 吉川寛 (70019876)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 柳田充弘 (80025428)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 岡崎恒子 (10022584)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 片山勉 (70264059)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. SHINOMIYA Tomoyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

TAKIZAWA Haruhiko 滝澤 温彦

滝沢 温彦 タキサワ ハルヒコ

滝澤 温彦 タキサワ ハルヒコ

高澤 温彦 タキサワ ハルヒコ

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Studies on molecular assembly of replication proteins and regulation of their functions in initiation of chromosome DNA replication

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Regulation of initiation and elongation stages of DNA replicationPrincipal Investigator

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Mcm蛋白質ならびにMcmと相互作用する蛋白質複合体による複製モニター機構

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細胞複製装置:染色体の複製・分配機構

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Regulation of initiation of chromosome replicationPrincipal Investigator

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Studies on the factors required for the formation of high-order chromatin structure.Principal Investigator

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真核細胞DNA複製ライセンス因子の同定とその機能の解明Principal Investigator

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核構造に依存したDNA複製開始機構Principal Investigator

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細胞複製装置:染色体の複製・分配機構

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アフリカツメガエル卵無細胞系における核構造に依存したDNA複製開始機構Principal Investigator

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真核生物DNA複製開始許可因子の同定Principal Investigator

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構成的に活性化されているタンパク質リン酸化酵素の深索Principal Investigator

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カルシウムイオンによる血小板細胞内顆粒分秘の制御機構Principal Investigator

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カルシウムイオンによる血小板細胞内顆粒分泌の制御機構Principal Investigator

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TAKIZAWA Haruhiko 滝澤温彦

滝沢温彦タキサワハルヒコ

滝澤温彦タキサワハルヒコ

高澤温彦タキサワハルヒコ

[Book] 細胞核のダイナミックス再構成核におけるDNA複製の解析2004