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ISHIKAWA Takatoshi  石川 隆俊

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… Alternative Names

石川 隆敏  イシカワ タカトシ

下山 隆俊

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Researcher Number 30085633
Affiliation (based on the past Project Information) *help 2000 – 2001: National Institution for Academic Degrees, Faculty of University Evaluation and Research, Professor, 構, 教授
2000: 国立大学評価機構, 教授
1997 – 1999: 東京大学, 大学院・医学系研究科, 教授
1989 – 1999: 東京大学, 医学部, 教授
1993 – 1995: 東京大学, 医学部(医), 教授 … More
1991: 東京大学, 医学部(医), 教授
1990: 東京大学, 医学部(医)・病理, 教授
1989 – 1990: 東京大学, 医学部・病理, 教授
1989: 癌研, 実験病理部, 部長
1989: 癌研究所, 実験病理部, 部長
1988: 癌研究所, 実験 病理部, 部長
1988: 癌研究所, 実験病理, 部長
1987 – 1988: (財)癌研究会, 癌研究所・実験病理部, 部長
1986 – 1987: 癌研究所, 実験病理部, 部長
1986: 癌研, 実験病理, 部長
1986: 癌研究会, その他, 研究員
1985: (財)癌研究会, その他, 研究員 Less
Review Section/Research Field
Principal Investigator
Experimental pathology
Except Principal Investigator
Experimental pathology / Human pathology / Circulatory organs internal medicine / Biological Sciences / Embryonic/Neonatal medicine / General anatomy (including Histology/Embryology)
Keywords
Principal Investigator
DNA修復 / イニシエーション / 前癌病変 / 化学発癌 / イニシエーター / 突然変異 / がん遺伝子 / DNA複製 / 発癌の修飾 / 細胞周期 … More / 発癌遺伝子 / DNA付加体形成 / イニシエ-ション / DNA損傷 / 宿主・臓器環境 / 発癌リスク / 細胞動態 / 活性酸素 / DNA鋳型活性 / メチルトランスフェラーゼ / アルキル化DNA / イニシエ-タ- / DNA付加体 / 発癌と宿主因子 / 発癌と環境因子 / 発癌物質 / 細胞回転 / ミューテーター遺伝子 / 突然変異上昇 / 遺伝子多型 / 多型タンパク不安定性 / replication error / hMSH3 / E2F4 / 遺伝子変異 / ミスマッチ修復 / MTH1遺伝子 / ヒト腫瘍 / APエンドヌクレアーゼ / AhR遺伝子 / 遺伝子ノックアウトマウス / ベンツピレン / 発がん感受性 / 芳香族炭化水素 / p450CYP1A1 / 薬物代謝酵素 / 転写誘導 / DNAー発癌物質付加体 / 発癌 / トランスジェニックマウス / 老化 / O^6-メチルグアニン / DNA損傷修復 / 発癌予防 / MGMT / Transgenic mice / O^6-methylguanine / Liver carcinogenesis / Nitrosamine / p53欠損 / ノックアウトマウス / 脳腫瘍 / 経胎盤発癌 / schwannoma / neu 遺伝子、活性化 / エチルニトロソウレア / neu遺伝子、活性化 / p53 / brain tumor / knockout mice / glioblastoma / medulloblastoma / apoptosis … More
Except Principal Investigator
DNA修復 / 代謝的活性化 / DNA付加体 / 肝癌 / C型肝炎 / 肝炎ウイルス / CYP1A1 / 発がん / ポリADPーリボシル化 / モノADPーリボシル化 / ミクロチスチン / CNーTPBP / DNA傷害 / ras遺伝子 / p53遺伝子 / 化学発癌 / 活性中間体 / アポトーシス / ウイルス性肝炎 / 輸血 / B型肝炎 / ミヤンマー国 / 鉄過剰症 / サラセミア / AhR遺伝子 / 遺伝子ノックアウトマウス / ジメチルベンツアントラセン / プログレッション / 発がん感受性 / がん遺伝子 / がん抑制遺伝子 / International Exchange Program / Oncogenes / Tumor Suppressor Genes / 色素性乾皮症 / トランスジェニックマウス / DNA repair / エンドヤリン1 / ジーンターゲティング / ノックアウト・マウス / 先天性疾患 / 神経堤細胞 / 発生 / エンドセリン / 血圧調節 / 胎児発達 / モデル動物 / Endothelin-1 / Gene-targeting / Congenital diseases / Neural crest / Development / hepatocellular carcinoma / Myanmar / CYP1B1 / Fas / ポリADPーリボース / ポリADPーリボース合成酵素 / モノADPーリボシル化酵素 / 情報伝達 / Gータンパク質 / 遺伝子発現 / オカダ酸クラスプロモーター / 発がんプロモーター / カリキュリンA / プロテインフォスファターゼ / アラキドン酸代謝 / メタロチオネイン / 遺伝子導入細胞 / ホタル・ルシフェラーゼ / メタロチオネイン遺伝子 / オカダ酸 / オカダ酸クラス発がんプロモ-タ- / 蛋白質脱リン酸化酵素2A / プロスタグランジンE_2 / protein kinase C / モノクロ-ン抗体 / mimー1タンパク質 / mybタンパク質 / Gタンパク質 / rhoタンパク質 / 癌原物質 / 種差 / 性差 / 臓器特異性 / ヒドロキシアリ-ルアミン / 食品中発がん物質ヘテロサイクリックアミン / IQによる扁平上皮がん / ラット大腸がん / ラット腎細胞がん / ウサギ腎芽腫 / WT遺伝子 / チトクロームP-450 / 細胞増殖 / P450 / アセチル化酵素 / Myb / ポリ(ADP-リボース)合成酵素(PAP) / PPly2 / p21 / MDM-2 / ラット肝発癌 / 鉄過剰 / ヤンゴン / ヘモグロビン等電点電気泳動 / 遺伝子検索 / p53変異 / 供血者 / 鉄欠乏 / シャンマー / マラリア / ヘモグロビン異常症 / 鉄代謝 / ジベンゾ[a, l]ピレン / 不死化;myc遺伝子 / 初代細胞 / トランスホーメーション / 初期胎児組織 / ショウジョウバエの劣性腫瘍遺伝子 / IL-2レセプターの発現 / ポリADP-リボース / ADP-リボシル化 / cDNA / モノクローン抗体 / マウス肝がんがん遺伝子 / ラット肝がんがん遺伝子 / rafの発現上昇 / 新しいがん遺伝子 / tcoがん遺伝子 / ゴールデンハムスター胎児培養細胞 / 染色体欠失 / ポリ(ADP-リボース)合成酵素 / モノ(ADP-リボース)合成酵素 / ポリ(ADP-リボース)合成酵素cDNA / 肝発がん / プロモーター / ポリ(ADP-リボシル)化 / モノ(ADP-リボシル)化 / IQ / raf / 放射線 / 直接誘発胸腺腫 / 間接誘発胸腺腫 / K-ras / 染 色体欠損 / プラスチック / 自然肝発がん / 高転移生 / 39KD蛋白質 / シグナル伝達 / がん細胞 / がん転移 / ヒトゲノム / 2国間共同研究 / がん遣伝子 / がん抑制遣伝子 / French-Japanese Collaborative Program in Cancer Research / German-Japanese Collaborative Program in Cancer Research / Signal Transduction / DNA Repair / Cancer Metastasis / 活性酵素 / 突然変異 / アルキル化剤 / ノックアウトマウス / 活性酸素 / 遺伝子ターゲッティング / ES細胞 / 紫外線 / モデルハウス / モデルマウス / xeroderma pigmentosum / active oxygen / carcinogenesis / mutation / alkylating agent / transgenic mice / knockout mice / O^6-メチルグアニン / メチルトランスフェラーゼ / 遺伝子欠損マウス / 疾患モデル / 0^6-メチルグアニン / 発癌予防 / O^6 -methylguanine / Methyltransferase / Transgenic mouse / Gene targeting mouse / Xeroderma pigmentosum / Animal model for disease / 血圧 / トランスジェニック・マウス / 先天性心疾患 / Knock-out mice / Blood pressure / Transgenic mice / 遺伝子多型 / 遺伝子 / ジ-ソターゲティング / 神経提細胞 / ジーンターダティング / 遺伝子診断 / Knock-out mouse / Polymorphism / Genetic diagnosis / 肝細胞癌 / 異常ヘモグロビン / ミヤンマー / 血清フェリチン / 自由鉄 / iron overload / thalassemia / hepatitis.B / hepatitis.C / hepatitis virus / abnormal hemoglobin / 心筋症 / 遺伝子治療 / サルコグリカン / AAVベクター / 予後 / 細胞骨格蛋白 / 薬物療法 / リポソーム / サイコグリカン / Gene / Therapy / rAAV / δ-SG / Lac Z / CMV / Echocardiography / ベンツピレン / ジベンゾ[a,l]ピレン / 芳香族炭化水素 / p450CYP1A1 / 薬物代謝酵素 / 転写誘導 / AhR gene / Knockout mice / Benzo[a]pyrene / DMBA / Dibenzo[a, l]pyrene / Progression / ミャンマー / 鉄 / 鉄反応エレメント結合蛋白 / Fas リガンド / 分子組織細胞化学 / Fasリガンド / 肝炎ウィルス / iron / iron-responsive element binding proteins / hepatitis viruses / apoptosis / Fas ligand / molecular histochemistry / ヒトレトロウイルス / ヒトがん遺伝子 / サイトカイン / 増殖因子 / Human Gene Mapping / Cytokines / Growth Factors / French-Japanese collaborative programe in cancer research / German-Japanese collaborative program in cancer research Less
  • Research Projects

    (41 results)
  • Co-Researchers

    (139 People)
  •  AhR遺伝子欠損マウスの発癌抵抗性に関する研究

    • Principal Investigator
      中鶴 陽子
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      The University of Tokyo
  •  Effect of iron as an environmental poisonous compound upon the precocious development of human hepatocellular carcinoma in Myanmar

    • Principal Investigator
      KOJI Takehiko
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General anatomy (including Histology/Embryology)
    • Research Institution
      Nagasaki University
  •  ミャンマー国肝がん発生要因としての輸血関連疾患と鉄過剰症の調査研究

    • Principal Investigator
      岡田 茂
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Okayama University
  •  AhR遺伝子欠損マウスの発癌抵抗性に関する研究Principal Investigator

    • Principal Investigator
      石川 隆俊
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokyo
  •  Role of carcinogenesis in aromatic hydrocarbons in Ah (dioxin) receptor knockout mice

    • Principal Investigator
      NAKATSURU Yoko
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      University of Tokyo
  •  ミャンマー国肝癌発生要因としてのサラセミア症の鉄過剰症と輸血関連疾患の調査研究

    • Principal Investigator
      岡田 茂
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Field
      Human pathology
    • Research Institution
      Okayama University
  •  Gene therapy of advanced heart failure

    • Principal Investigator
      TOYO-OKA Teruhiko
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      University of Tokyo
  •  ヒト発がんにおける複製・修復遺伝子の変異Principal Investigator

    • Principal Investigator
      石川 隆俊
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  Analysis of the brain tumor transplacentally induced in p53 knockout micePrincipal Investigator

    • Principal Investigator
      ISHIKAWA Takatoshi
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      The University of Tokyo
  •  Hepatocarcinogenetic Studies in Myanmar Thalassemiacs

    • Principal Investigator
      OKADA Shigeru
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      Human pathology
    • Research Institution
      OKAYAMA UNIVERSITY
  •  腫瘍細胞のDNA機能異常における核タンパク質の相互作用

    • Principal Investigator
      三輪 正直
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      University of Tsukuba
  •  Importance of DNA repair in carcinogenesis : Insight for transgene or gene targeting experiments.

    • Principal Investigator
      NAKATSURU Yoko
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      The University of Tokyo
  •  ESTABLISHMENT OF MICE DEFICTENT IN A VASOACTIVE PEPTIDE BY GENE TARGETING AND THEIR APPLICATION TO PATHOPHYSIOLOGICAL ANALYSIS

    • Principal Investigator
      KURIHARA Hiroki
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      University of Tokyo
  •  ESTABLISHMENT OF AN ANIMAL MODEL FOR CONGENITAL CRANIOFACIAL DISEASES BY GENE TARGETING AND DEVELOPMENT OF THEIR GENETIC DIAGNOSIS.

    • Principal Investigator
      KURIHARA Hiroki
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Embryonic/Neonatal medicine
    • Research Institution
      University of Tokyo
  •  宿主・臓器環境とイニシエーションリスクの変動Principal Investigator

    • Principal Investigator
      石川 隆俊
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  化学発癌における活性中間体の動態と標的臓器DNA傷害-臓器および種特異性との関連

    • Principal Investigator
      加藤 隆一
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Keio University
  •  Establishment of DNA repair-deficient or-superproficient mice and their development and molecular basis of genetic instability

    • Principal Investigator
      TANAKA Kiyoji
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  Initiation and Its Inhibition by Carcinogenes in transgenic Mice Carried with MGMT Gene.Principal Investigator

    • Principal Investigator
      ISHIKAWA Takatoshi
    • Project Period (FY)
      1993 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Experimental pathology
    • Research Institution
      University of Tokyo
  •  宿主・臓器環境とイニシエーションリスクの変動Principal Investigator

    • Principal Investigator
      石川 隆俊
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  化学発癌における活性中間体の動態と標的臓番DNA傷害ー臓器よおび種特異性との関連

    • Principal Investigator
      加藤 隆一
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Keio University
  •  ADPーリボシル化の調節と発がん

    • Principal Investigator
      三輪 正直
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      University of Tsukuba
  •  宿主・臓器環境とイニシエ-ションリスクの変動Principal Investigator

    • Principal Investigator
      石川 隆俊
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  化学発癌における活性中間体の動態と標的臓器DNA傷害ー臓器および種特異性との関連

    • Principal Investigator
      加藤 隆一
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Keio University
  •  実験動物がんのがん遺伝子

    • Principal Investigator
      NAGAO Minako
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  Cooperation and information exchange with European countries.

    • Principal Investigator
      KUROKI Toshio
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      University of Tokyo
  •  化学発癌におけるイニシエ-ション機構の解析Principal Investigator

    • Principal Investigator
      石川 隆俊
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  ADPーリボシル化の調節と発がん

    • Principal Investigator
      三輪 正直
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      University of Tsukuba
  •  発がんプロモーションの機構とその阻害

    • Principal Investigator
      藤木 博太
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  遺伝子導入による自己発光性哺乳類細胞の構築とその細胞癌化・分化の解析への応用

    • Principal Investigator
      宇多小路 正
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Japanese Foundation For Cancer Research
  •  発がんプロモ-ションの機構とその阻害

    • Principal Investigator
      藤木 博太
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  化学発癌におけるイニシエーション機構の解析Principal Investigator

    • Principal Investigator
      石川 隆俊
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  化学発癌におけるイニシエーション機構の解析Principal Investigator

    • Principal Investigator
      石川 隆俊
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Japanese Foundation For Cancer Research
  •  実験動物がんのがん遺伝子

    • Principal Investigator
      長尾 美奈子
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  Cooperation and Information Exchange with European Countries

    • Principal Investigator
      KUROKI Toshio
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Institute of Medical Science, University of Tokyo
  •  実験動物がんのがん遺伝子

    • Principal Investigator
      長尾 美奈子
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  細胞の不老不死と腫瘍遺伝子による試験管内発がんの関連

    • Principal Investigator
      近藤 宗平
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kinki University
  •  発がんにおける蛋白質のモノおよびポリADP-リボシル化について

    • Principal Investigator
      三輪 正直
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  発がんにおける蛋白質のモノおよびポリADPリボシル化について

    • Principal Investigator
      三輪 正直
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  発癌のイニシェーションの特性と修飾Principal Investigator

    • Principal Investigator
      石川 隆俊
    • Project Period (FY)
      1985
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Japanese Foundation For Cancer Research
  •  発癌のイニシェーションの特性と修飾Principal Investigator

    • Principal Investigator
      石川 隆俊
    • Project Period (FY)
      1985 – 1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Japanese Foundation For Cancer Research
  •  発癌のイニシエーションの特性と修飾Principal Investigator

    • Principal Investigator
      石川 隆俊
    • Project Period (FY)
      1985 – 1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Japanese Foundation For Cancer Research
  • 1.  NAKATSURU Youko (00237314)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 2.  OKADA Shigeru (60135556)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 3.  多田 万里子 (90073113)
    # of Collaborated Projects: 7 results
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