OSAME Mitsuhiro 納光弘

Researcher Number	10041435
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2005 – 2006: 鹿児島大学, 大学院医歯学総合研究科, 教授 2002 – 2005: Kagoshima University, Graduate School of Medicine and Dental Sciences, Professor, 大学院・医歯学総合研究科, 教授 1987 – 2002: 鹿児島大学, 医学部, 教授 1993: 鹿児島大学医学部, 教授 1993: 鹿児島大学, 医学部・, 教授 1991: 鹿児島大学, 医学部・第三内科(内科学・神経内科学), 教授
Review Section/Research Field	Principal Investigator Neurology / Neurology / 内科学一般 Except Principal Investigator Neurology / Neurology / Hematology / Immunology / 内科学一般 / Respiratory organ internal medicine / 神経内科学 / Pathological medical chemistry
Keywords	Principal Investigator HAM / HTLV-I / TSP / HTLVーI / ATL / HTLV-Iプロウイルス量 / HTLV-1 / ROC曲線 / HTLV-Iキャリア / PCR定量 … More / HTLV-I associated myelopathy / STLV / neurotropism / in situ hybridization / HAM発症 / 重回帰分析 / 疾患感受性 / 遺伝子多型 / HLA / 細胞傷害性Tリンパ球 / レトロウイルス / 成人T細胞白血病ウイルス / STLV-I / 成人T細胞白血病 / HTLV / neopterin / In situ hybridization / immunohistochemistry / Neurotropism / Polymelase chain reaction / 薬剤性横紋筋融解 / 細胞内カルシウム濃度 / ミオトニア / 細胞内Ca結合蛋白 / Caチャンネル / 宿主要因解析 / 逆転写酵素阻害剤 / HTLV-Iウィルス量 / cut off値 / 有効例、無効例 / 宿主因子 / Shh / Gli2 / RT-PCR / フローサイトメーター / 発症規定因子 / プロテオグリカン / aggrecan / VNTR / 感度 / 特異度 / 脳組織 / 関節組織 / 軟骨組織 / 細胞外基質 / 中枢神経組織 / 細胞障害性Tリンパ球 / ペプチド / MHC多量体 / HTLV-I associated mylopathy / HTLVーI脊髄症 / 脊髄症 / HTLVーI関連症候群 / シェグレン症候群 / HTLVーI筋炎 / Retrovirus / HTLV-II / HIV-I / HIV-II / SIV / HIV / Adult T-cell Leukemia / 分子疫学 / 系統解析 / 少数民族 / 分子系統解析 / ヒト細胞白血病 / STLV-1 / オランウータン / ピグミー / molecular epidemiology / phylogenetic analysis / ウイルス量 / ウイルス抗体価 / 感染細胞数 / proviral load / viral antibody / infected cell number / 宿主要因の解析 / ウイルス側の要因を解析 / 候補遺伝子解析 / Taxサブタイプ / 非HLA要因の解析 / HLA classI / HLA classII / プロウイルス量 / 細胞傷害性T細胞 / HAM occurrence / Analysis of Genetic Factors / Analysis of Viral Factors / ROC curve / Candidate Gene Analysis / Tax subtype / non-HLA factors / Regression Analysis / 治療開発 / 発症予測 / 選択的MMP阻害剤 / 疾患感受性遺伝子 / 予後判定 / dN / dS比 / 治療薬開発 / 高齢発症 / MMP / MMP阻害剤 / HTLM-Iプロウイルス量 / HTLV-I-associated myelopathy / HTLV-I proviral load / Therapy / Prognosis / metalloproteinase inhibitor / susceptible genes / cytotoxic T lymphocytes / ミエロパチ- / HAM@TSP / レトロウィルス / ミエロパチー / 痙性脊髄麻痺 / スローウィルス / ミオパチー / HTLVーIーassociated / Treatment / Blood Transfusion / Epidemiology / Clincal / HTLV-I Associated Myelopathy … More Except Principal Investigator HAM / HTLV-I / TSP / Desert hedgehog / エイズ / HIV / ATL / 血友病 / 免疫不全 / HTLV-1 / Thrombomodulin / Transgenic mouse / シュワン細胞 / collagen VI / レトロウィルス / HTLVー1 / 動脈硬化 / 脳血管性痴呆 / 成人T細胞白血病 / ヒト免疫不全ウイルス / サル免疫不全ウイルス / AIDS / SIV / トロンボモジュリン / MPTP / マ-モゼット / 培養血管内皮細胞 / Pathogenesis / Immunohistochemistry / Autopsy / AP-1 / GFAP / in situ PCR / immunohistochemistry / MMSE / Crow-Fukase syndrome / POEMS syndrome / VEGF / platelet / 性分化異常症 / 遺伝性末梢神経障害 / minifascicle / ノックアウトマウス / Hereditary neuropathy / ALS / HMSNP / KW / Ullrich病 / Collagen VI / Ullrich's disease / 末梢神経 / Schwann cell / Bethlem myopathy / collagenopathy / NG2 proteoglycan / experimental therapy / laminin β1 / 実験的アレルギ-性神経炎 / 自己免疫 / 脱髄 / 免疫調整剤 / 免疫異常 / レトロウイルス / 重感染 / 脳腱黄色腫症 / リポ蛋白代謝 / 動脈硬化症 / コレスタノ-ル / コレステロ-ル / 胆汁アルコ-ル / 植物ステロ-ル / 胆汁酸 / ウィルス疾患 / 免疫細胞活性化 / ADF / Thioredoxin / 慢性関節リウマチ / ウイルス疾患 / TRX / EBV / redox regulation / NFーkB / 転写活性因子 / ドリコール / イソプレン / HDL(高比重リポ蛋白) / アポリポ蛋白 / WHHL / アルツハイマー型痴呆 / 接触因子 / VHA-4 / VCAM-1 / MCP-1 / ICAM-1 / HTLV-I感染細胞 / 間質性肺炎 / BAL / CD4陽性細胞 / in sitiu PCR法 / ヒトT細胞白血病ウイルス / Adult T-cell leukemia / Human immunodeficiency virus / Simian immunodeficiency virus / Human T-cell leukemia virus / STLVー1 / STLV-1 / 血管内皮細胞 / サイクリックAMP / プロスタサイクリン / thrombomodulin / TNF / ILーI / 血栓症 / テラトカルチノ-マ / endothelial cells / cyclic AMP / cytokine / パーキンソン病 / 霊長類 / マーモセット / 中毒 / 神経変性疾患 / 老化 / パ-キンソン病 / Parkinson's disease / Primate / Common marmoset / Toxin / Degenerative disorder / Aging / トロンビン受容体 / 血管平滑筋細胞 / 冠動脈 / 冠動脈血栓症 / 冠動脈血栓〓 / endothelium / トロンビン / 腎系球体 / 膠原病 / Cultured Endothelilal Cells / Thrombin Receptor / Vascular Smooth Nusle Cells / Coronary Artery / Coronary Artery Thrombosis / Neuropathology / マーモゼット / 動物モデル / 神経病理 / 発症機序 / Neuropatholgy / Marmoset / カルニチン / 高アンモニア血症 / 尿素サイクル / 心肥大 / differential display / 長鎖不飽和脂肪酸 / JUS(juvenile Visceral Steatosi s)マウス / c-jun / JVS(Juvenile Visceral Steatosis)マウス / jvs(juvenile visceral steatosis)マウス / グルココルチコイド / Atrial natriuretic factor / 膜輸送活性 / 遺伝子発現 / Carnitine / Hyperammonemia / Urea cycle / Cardiac hypertrophy / Long-chain unsaturated fatty acid / JVS (Juvenile Visceral Steatosis) mouse / Differential display / ミトコンドリア脳筋症 / アポトーシス / Fas抗原 / タイプ2筋線維萎縮 / DNA異常 / ミオパチー / 眼病変 / Fas mRNA / タイプ2筋線維 / ミトコンドリアDNA / 培養筋芽細胞 / タイプ2線維 / Mitochondrial encephalomyopathy / Apoptosis / Fas antigen / Type 2 muscle fiber atrophy / DNA mutation / Myopathy / Ocular manifestations / 神経栄養因子 / ミッドカイン / 脳梗塞 / ラット / アストロサイト / 脳虚血けいれん / 胎児脳形成 / ヘパリン / 脳虚血 / BDNF / NGF / HSP70 / 神経細胞 / Neurotrophic factor / Midkine / cerebral infarction / rat / astrocytes / プロウイルス量 / 持続感染 / 免疫組織化学 / 分子病理 / ウイルス / proviral load / persistent infection / molecular pathology / 神経の加齢変化 / 痴呆 / 遺伝的素因 / 離島高齢者 / 脳血管障害 / ACE遺伝子多型 / ミトコンドリアDNA5178多型 / 神経疾患 / Aging effects on nervous system / Dementia / Genetic factors / Elders in an island community / Cerebrovascular disorders / Polymorphism of ACE gene / Mitochondria DNA 5178 / megakaryocyte / transgenic mouse / naked VEGF cDNA / neuropathy / nude mouse / matrix metalloproteinase / isoform / intraneural injection / coagulation / glioblastoma / 脳脊髄液細胞 / in situ hybridization法 / 免疫組織学的方法 / レーザスキャニングサイトメータ / cerebrospinal fluid cells / in situ hybridization / Laser Scanning Cytometer / transgenic mice / 性分化異常 / hedgehog / Gonadal dysgenesis / 遺伝性ニューロパチー / 連鎖解析 / 近位筋優位 / 第三染色体 / 候補遺伝子 / HMSN / Linkage analysis / Proximal dominant / Chromosome 3 / Candidate genes / HTLV-I関連脊髄症 / 細胞傷害性Tリンパ球 / 変異ウイルス / 同義置換 / 非同義置換 / HTLV-I関連脊髄症(HAM) / HTLV-I-associated myelopathy / cytotoxic T lymphocyte / mutant virus / viral evolution / 細胞外マトリックス / Protoglycan / Fibronectin受容体 / NGZproteoglycan / myosin heavy chain / fibronectin / Extracellular matrix / Proteoglycan / Fibronectin receptor / patched / 神経再生 / 行動解析 / 遺伝性抹消神経障害 / peripheral nervous system / Patched / lamininβ1 / tenascin C / CD44 / 実験的治療 / 糖尿病 / 再生 / うつ病 / peripheral nerve / diabetes mellitus / hereditary neuropathy / がん遺伝子 / がん抑制遺伝子 / ヒトレトロウイルス / ヒトがん遺伝子 / DNA修復 / 発がん / サイトカイン / 増殖因子 / International Exchange Program / Human Gene Mapping / Oncogenes / Tumor Suppressor Genes / Cytokines / Growth Factors / French-Japanese collaborative programe in cancer research / German-Japanese collaborative program in cancer research / HTLV-I関連疾患 / HTLV-I脊髄症 / ハム / HILV-I associated Myelopathy / HTLV-I-Associated / Spastic Paraparesis / Retrovirus / Polyarthritis / alpha-Interferon Less

中枢神経組織におけるウイルス特異的細胞傷害性Tリンパ球の検出Principal Investigator
- Principal Investigator
  
  納光弘
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Neurology
- Research Institution
  Kagoshima University
Study for the pathogenesis of neuropathy with Desert hedgehog gene mutation and development for the treatment
- Principal Investigator
  
  UMEHARA Fujio
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kagoshima University
Studies on pathophysiology and experimental therapy of Ullrich's disease with collagen VI deficiency.
- Principal Investigator
  
  HIGUCHI Itsuro
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kagoshima University
The study of neurological abnormalities in the patients with Desert hedgehog gene mutation
- Principal Investigator
  
  UMEHARA Fujio
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kagoshima University
中枢神経及び関節組織に共通のプロテオグリカンとCD44分子に関する研究Principal Investigator
- Principal Investigator
  
  納光弘
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Neurology
- Research Institution
  Kagoshima University
Exploitation of new therapies for HTLV-I-assotiated myelopathyPrincipal Investigator
- Principal Investigator
  
  OSAME Mitsuhiro
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Neurology
- Research Institution
  Kagoshima University
Cytotoxic T lymphocytes and viral mutations in HTLV-I-associated myelopathy
- Principal Investigator
  
  KUBOTA Ryuji
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kagoshima University
Pathological and molecular genetic studies on collagen VI deficient Ullrich's disease
- Principal Investigator
  
  HIGUCHI Itsuro
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kagoshima University
Research for hereditary neuropathy caused by desert hedgehog gene mutation
- Principal Investigator
  
  UMEHARA Fujio
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kagoshima University
Molecular analysis of a new type of hereditary motor sensory neuropathy with proximal dominant involvement
- Principal Investigator
  
  NAKAGAWA Masanori
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kyoto Prefectural University of Medicine
  Kagoshima University
Development of simultaneous and quantitative detection system of human T-lymphotropic virus type I proviral DNA and transcripts in cerebrospinal fluid cells from patients with human T-lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis.
- Principal Investigator
  
  MORITOYO Takashi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kagoshima University
レトロウイルス逆転写酵素阻害剤によるHAM新治療法開発に関する研究Principal Investigator
- Principal Investigator
  
  納光弘
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Neurology
- Research Institution
  Kagoshima University
Longitudinal study in an island community for aging effects on neurological findings and genetic factors on vascular dementia
- Principal Investigator
  
  NAKAGAWA Masanori
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kagoshima University
HAMの臨床病態・発症機序の解明並びに新治療法の開発に関する研究Principal Investigator
- Principal Investigator
  
  OSAME Mitsuhiro
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Kagoshima University
Research for the pathogenesis and treatment of Crow-Fukase syndrome
- Principal Investigator
  
  ARIMURA Kimiyoshi
- Project Period (FY)
  1999 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Kagoshima University
Research on Pathomechanism and a novel treatment of HTLV-I-associated myelopathy (HAM)Principal Investigator
- Principal Investigator
  
  OSAME Mitsuhiro
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Kagoshima University
HTLV-I感染者における間質性肺炎の研究
- Principal Investigator
  
  川畑政治
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kagoshima University
MOLECULAR PATHOLOGICAL ANALYSIS OF NERVOUS DISEASES CAUSED BY CHRONIC VIRAL INFECTION
- Principal Investigator
  
  IZUMO Shuji
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  KAGOSHIMA UNIVERSITY
筋細胞壊死におけるCa^<2+>依存性機構の解明Principal Investigator
- Principal Investigator
  
  納光弘
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kagoshima University
HAMにおける細胞接着因子の研究
- Principal Investigator
  
  UMEHARA Fujio
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kagoshima University
Pathology and Molecular Evolution of HTLV in AsiaPrincipal Investigator
- Principal Investigator
  
  OSAME Mitsuhiro
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  Neurology
- Research Institution
  Kagoshima University
The Effect of Neurotrophic Factor MK on the Expression and Repair of Brain injury
- Principal Investigator
  
  YOSHIDA Yoshihiro
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kagoshima University
Epidemiology and pathology of human retrovirus infectionPrincipal Investigator
- Principal Investigator
  
  OSAME Mitsuhiro
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Kagoshima University
Pathogenesis and pathophysiology of inherited carnitine deficiency using carnitine-deficient JVS mice
- Principal Investigator
  
  SAHEKI Takeyori
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kagoshima University
Study of apoptosis in mitochondrial diseases
- Principal Investigator
  
  NAKAGAWA Masanori
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kagoshima University
ドリコールの生理機能及び病的動態に関する研究
- Principal Investigator
  
  吉留宏明
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Kagoshima University
Epidemiology and pathology of human retro virus infection.Principal Investigator
- Principal Investigator
  
  OSAME Mitsuhiro
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Kagoshima Universitiy
Regulation of Expression of Thrombomodulin on the Cultured Human Umbilical Vein Endothelila Cells and Pathomechanism of Thrombosis
- Principal Investigator
  
  MARUYAMA Ikuro
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  KAGOSHIMA UNIVERSITY
Pathogenesis of HTLV-I-associated Myelopathy (HAM) ; Neuropathological Analysis and Establishment of Animal Model
- Principal Investigator
  
  IZUMO Shuji
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  神経内科学
- Research Institution
  KAHOSHIMA UNIVERSITY
エイズの総合的基礎研究柱4.エイズの病態に関する研究
- Principal Investigator
  
  高月清
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kumamoto University
ウィルス疾患における免疫細胞活性化異常に関する総合研究
- Principal Investigator
  
  YODOI Junji
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  Immunology
- Research Institution
  Kyoto University
Seroepidemiology of ATL/AIDS-related viruses and comparative virology and pathology
- Principal Investigator
  
  HAYAMI Masanori
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Kyoto University
RESEARCH FOR THE PATHOMECHANISM, EPIDEMILOGY AND TREATMENTS FOR HAM AND HTLV-I RELATED DISORDERS.Principal Investigator
- Principal Investigator
  
  OSAME Mitsuhiro
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  内科学一般
- Research Institution
  KAGOSHIMA UNIVERSITY
HTLVーIのneurotropismに関する研究(特にATLとHAMの病理組織をもちいたin situ hybridizationによるvirusの検索)Principal Investigator
- Principal Investigator
  
  納光弘
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kagoshima University
エイズの総合的基礎研究柱4.エイズの病態に関する研究
- Principal Investigator
  
  高月清
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kumamoto University
脳腱黄色腫症(CTX)における神経症状および動脈硬化発症機序に関する研究
- Principal Investigator
  
  栗山勝
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kagoshima University
HTLV-Iのneurotropismに関する研究(特にATLとHAMの病態組織をもちいたin situ liybridization によるvirusの検索)Principal Investigator
- Principal Investigator
  
  納光弘
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kagoshima University
An Investigation of the Expression of Thrombomodulin in Cultured Human Umbilical Vein Endothelial Cells
- Principal Investigator
  
  MARUYAMA Ikuro
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Kagoshima University
Effects of aging on MPTP-treated common marmosets
- Principal Investigator
  
  NOMOTO Masahiro
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  KAGOSHIMA UNIVERSITY
脱髄疾患の病態、治療に関する実験的研究
- Principal Investigator
  
  IZUMO S
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kagoshima University
エイズの総合的基礎研究柱4.エイズの病態に関する研究
- Principal Investigator
  
  TAKATSUKI Kiyoshi
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kumamoto University
Seroepidemiology of ATL・AIDS-related viruses, and comparative virology and pathology.
- Principal Investigator
  
  HAYAMI Masanori
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Kyoto University
Cooperation and Information Exchange with European Countries
- Principal Investigator
  
  KUROKI Toshio
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Institute of Medical Science, University of Tokyo
Research on pathogenesis, epidemiology and treatment for HTLV-I related neurological disorders
- Principal Investigator
  
  IGATA Akihiro
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  Neurology
- Research Institution
  Kagoshima University
Research of Clinical Features and Pathomechanism of HAMPrincipal Investigator
- Principal Investigator
  
  OSAME Mitsuhiro
- Project Period (FY)
  1987 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Kagoshima University

All 2006 2005 2003 2002

All Journal Article Book

[Book] Gann Monograph on Cancer Research No.502003
- Author(s)
  Fujio Umehara, Mitsuhiro Osame
- Total Pages
  7
- Publisher
  Japan Scientific Societies Press
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590900
[Journal Article] New mutation of gap junction protein beta1(GJB1) gene in X-linked hereditary motor and sensory neuropathy.2006
- Author(s)
  Fujio Umehara, Yumiko Arimura, Mitsuhiro Osame, S. Minato, Keiichi Nakahara.
- Journal Title
  
  J Peripher Nerv Syst 11(1)
  
  Pages: 96-97
- Data Source
  KAKENHI-PROJECT-17590884
[Journal Article] New mutation of gap junction protein beta1 (GJB1) gene in X-linked hereditary motor and sensory neuropathy.2006
- Author(s)
  Fujio Umehara, Yumiko Arimura, Mitsuhiro Osame, S. Minato, Keiichi Nakahara.
- Journal Title
  
  J Peripher Nerv Syst 11
  
  Pages: 96-97
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590884
[Journal Article] Early clinical signs and imaging findings in Gerstmann-Straussler-Scheinker syndrome (Pro102Leu).2006
- Author(s)
  Hitoshi Arata, Hiroshi Takashima, Ryuki Hirano, Hisanori Tomimitsu, Koichi Machigashira, Kotaro Izumi, Mitsuro Kikuno, A.R. Ng, Fujio Umehara, Takayo Arisato, Ryuichi Ohkubo, Y. Nakabeppu, M. Nakajo, Mitsuhiro Osame, Kimiyoshi Arimura.
- Journal Title
  
  Neurology 66
  
  Pages: 1672-1678
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590884
[Journal Article] New mutation of gap junction protein beta1 (GJB1) gene in X-linked hereditary motor and sensory neuropathy.2006
- Author(s)
  Fujio Umehara, Yumiko Arimura, Mitsuhiro Osame, et al.
- Journal Title
  
  J Peripher Nerv Syst 11(1)
  
  Pages: 96-97
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590884
[Journal Article] Relapsing cervical cord lesions on MRI in patients with HTLV-I-associated myelopathy.2006
- Author(s)
  Fujio Umehara, Hiroyasu Tokunaga, Yoichi Hokezu, Ei Hokonohara, Koichi Yoshishige, Tadafumi Shiraishi, Ryuichi Okubo, Mitsuhiro Osame.
- Journal Title
  
  Neurology 66
  
  Pages: 289-289
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590884
[Journal Article] MRI studies of spinal visceral larva migrans syndrome.2006
- Author(s)
  Fujio Umehara, Hideki Ookatsu, Daisuke Hayashi, Akifumi Uchida, Yukari Douchi, H.Kawabata, Rina Goto, Akihiro Hashiguchi, Eiji Matsuura, Ryuichi Okubo, Itsuro Higuchi, Kimiyoshi Arimura, Y.Nawa, Mitsuhiro Osame.
- Journal Title
  
  J Neurol Sci 249
  
  Pages: 7-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590884
[Journal Article] Unilateral toe-walking secondary to intramuscular hemangioma in the gastrocnemius.2006
- Author(s)
  Fujio Umehara, E.Matsuura, S.Kitajima, M.Osame.
- Journal Title
  
  Neurology 65
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590884
[Journal Article] Unilateral toe-walking secondary to intramuscular hemangioma in the gastrocnemius2005
- Author(s)
  Fujio Umehara, E.Matsuura, S.Kitajima, M.Osame.
- Journal Title
  
  Neurology 65・7
- Data Source
  KAKENHI-PROJECT-17590884
[Journal Article] Unilateral toe-walking secondary to intramuscular hemangioma in the gastrocnemius.2005
- Author(s)
  Fujio Umehara, E.Matsuura, S.Kitajima, M.Osame
- Journal Title
  
  Neurology 65(7)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590884
[Journal Article] 「研究成果報告書概要(欧文)」より2003
- Author(s)
  Fujio Umehara, Mitsuhiro Osame
- Journal Title
  
  Gann Monograph on Cancer Research(Japan scientific societies Press) No.55
- Data Source
  KAKENHI-PROJECT-15590900
[Journal Article] HAMの病態と治療2003
- Author(s)
  納光弘, 宇宿功市郎, 梅原藤雄, 斉藤峰輝, 古川良尚, 久保田龍二, 他
- Journal Title
  
  日本内科学会雑誌 92・9
  
  Pages: 65-74
- NAID
  10011058589
- Data Source
  KAKENHI-PROJECT-15590900
[Journal Article] HAMの病態と治療2003
- Author(s)
  納光弘, 宇宿功市郎, 梅原藤雄, 斉藤峰輝, 古川良尚, 久保田龍二, 他
- Journal Title
  
  日本内科学会雑誌 92
  
  Pages: 65-74
- NAID
  10011058589
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590900
[Journal Article] 「研究成果報告書概要(欧文)」より2003
- Author(s)
  M.Osame, K.Usuku, Fujio Umehara, M.Saito, Y.Furukawa, R.Kubota, et al.
- Journal Title
  
  Nippon Naika Gakkai Zasshi 92
  
  Pages: 65-74
- Data Source
  KAKENHI-PROJECT-15590900
[Journal Article] Pathological mechanisms of human T-cell lymphotropic virus type I-associated myelopathy (HAM/TSP).2002
- Author(s)
  Osame M.
- Journal Title
  
  J Neurovirol. 8(5)
  
  Pages: 359-364
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207031

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OSAME Mitsuhiro 納 光弘

Research Projects

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Co-Researchers

中枢神経組織におけるウイルス特異的細胞傷害性Tリンパ球の検出Principal Investigator

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中枢神経及び関節組織に共通のプロテオグリカンとCD44分子に関する研究Principal Investigator

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Exploitation of new therapies for HTLV-I-assotiated myelopathyPrincipal Investigator

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レトロウイルス逆転写酵素阻害剤によるHAM新治療法開発に関する研究Principal Investigator

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HAMの臨床病態・発症機序の解明並びに新治療法の開発に関する研究Principal Investigator

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OSAME Mitsuhiro 納光弘