Ohno Shigeo 大野茂男

… Alternative Names

Researcher Number	10142027
Other IDs	https://orcid.org/0000-0002-1294-5269
External Links
Affiliation (Current)	2020: 順天堂大学, 医学(系)研究科(研究院), 特任教授 2020: 横浜市立大学, 医学研究科, 特任教授
Affiliation (based on the past Project Information) *help	2017: 横浜市立大学, 大学院医学系研究科, 講師 2015 – 2016: 横浜市立大学, 医学研究科, 教授 2014 – 2015: 横浜市立大学, 大学院医学系研究科, 教授 2011 – 2014: 横浜市立大学, 医学(系)研究科(研究院), 教授 2004 – 2012: 横浜市立大学, 医学研究科, 教授 … More
Review Section/Research Field	Principal Investigator Biological Sciences / Functional biochemistry / General medical chemistry / General medical chemistry / Human genetics / Human genetics / Cell biology / Pathological medical chemistry / Pathological medical chemistry Except Principal Investigator 物質生物化学 … More
Keywords	Principal Investigator プロテインキナーゼC / ASIP / プロテインキナーゼ / aPKC / PKC関連酵素 / 転写活性化 / ホルボールエステル / ジアシルグリセロール / ナンセンス変異 / PAR-3 … More Except Principal Investigator プロテインキナーゼC / 細胞内情報伝達 / Signal transduction / thyrotropin-releasing hormone / 細胞極性 / プロテインキナ-ゼC / ホルボ-ルエステル / カルシウムイオン / ホルモン / Protein kinase C / Hormone / Phorbol ester / 遺伝子診断 / 細胞増殖 / 細胞接着 / 細胞死 / 毛包幹細胞 / 脱毛 / 創傷治癒 / ヒストン遺伝子 / protein kinase C / IIIa / ホルボ-ルエステル受容体 / セリン・スレオニンリン酸化酵素 / Calcium / Protein-serine / threonine kinase / シグナル伝達 / がん遺伝子 / がん抑制遺伝子 / DNA修復 / apoptosis / Grb2 / SH3 / SH2 / NMR / ホルボールエステル / 脳下垂体培養細胞 / リン酸化 / Secretory mechanism / Pituitary clonal cells / Phosphorylation / von Hippel-Lindau病 / von Hippel-Lindau (VHL) disease / vinculin / actin fiber / PKCδ / 脱顆粒 / RBL-2H3細胞 / トランスロケーション / ヒスタミン / 炎症 / 遺伝子導入法 / ヘキソサミニダーゼ / von Hippel-Liedem病 / 発症病態 / 家系解析 / 家系登録 / 腎細胞癌 / 網膜血管腫 / 中枢神経血管芽腫 / VHL病 / 国際間交流研究 / がん / 細胞運動 / 組織 / 増殖 / 分化 / 浸潤 / 転移 / 浸潤・転移 / 接着 / 細胞外マトリックス / 休眠 / 遺伝子改変マウス / 毛包形成 / 皮膚幹細胞 / 皮膚発癌 / 幹細胞 / リボソームRNA遺伝子 / 転写因子 / 欠失変異体 / 点突然変異体 / 競合実験プロモーター / Tiプラスミド / 遺伝子移入植物 / rDNA / LTR / カルシウムプロテアーゼ遺伝子 / メタロチオネイン遺伝子 / トランス転写因子 / プロモター構造 / クロマチン構造 / カルシウムプロテア-ゼ / calcium protease / phorbol ester / GPIIb / インテグリンα_<IIb>β_3 / 血小板無力症 / 血小板凝集 / 血小板フィブリノゲン / 血漿フィブリノゲン / インテグリンα_<IIb> β_3 / IIIa複合体 / Fibrinogen結合部位 / PCR法 / cDNA異常 / 血小板凝集能欠損 / Platelet GPIIb / Integrin alpha_<IIb> beta_3 / Thrombasthenia / Platelet Aggregation / Intra-Platelet Fibrinogen / Plasma Fibrinogen / ダウンレギュレ-ション / セリン・スレオニリン酸化酵素 / プロテインクナ-ゼC / phorbol ester receptor / Down regulation / 細胞分化 / 細胞間相互作用 / がん転移 / ヒトがん / がん細胞 / ヒトゲノム / 2国間共同研究 / cell growth / cell differentiation / signal transduction / cell-cell interaction / cancer metastasis / human cancer / oncogene / tumor suppressor gene / Shc / Sos / デストリン / ミッドカイン / Link / Ash / 立体構造 / N-WASP / フィロポディア / 二成分系 / リン酸基転移反応 / 嫌気センサー / GRB2 / 神経突起伸長 / ArcB / Tob / リン酸化チロシン / プロリンに富むペプチド / 溶液構造 / Ras / ポリプロリンヘリックス / Solution Structure / three dimensional structure of protein / X-ray crystallography / destrin / midkine / 分泌制御機構 / 分泌機構 / 遺伝子導入 / 下垂体細胞 / 分子生物学 / Protein kinase C' / 遺伝相談 / 遺伝性腫瘍 / von Hippel-Lindau disease / genetic diagnosis / genetic counseling / 分泌 / ホリボールエステル / PKC Substrate / action fiber / 重合 / atypical protein kinase C・(aPKC) / VHL癌抑制遺伝子 / 胚細胞変異 / atypical protein kinase cλ / VHL遺伝子 / 癌抑制遺伝子 / atypical protein kinase C・(aPKC・) / アポトーシス / ノックアウトマウス / B細胞 / 増殖制御 / ジーンターゲティング / ES細胞 / ICE様プロテアーゼ / knockout mice / singal transduction / B cell / proliferation control / カルシウムプロテアーゼ / CANP / カルモジュリン / EFハンド構造 / プロファーゼ / プロテアーゼインヒビター / カルシウム / プロテアーゼ / 血小板膜糖蛋白GPIb / トロンビン結合部位 / 血小板膜GPIb / トロンビン凝集 / von Willebrand因子結合部位 / Platelet membrane GPIb / Thrombin-binding site / ヒトレトロウイルス / ヒトがん遺伝子 / 発がん / サイトカイン / 増殖因子 / International Exchange Program / Human Gene Mapping / Oncogenes / Tumor Suppressor Genes / Cytokines / Growth Factors / French-Japanese collaborative programe in cancer research / German-Japanese collaborative program in cancer research / リン脂質 / ジアシルグリセロ-ル / ホルボールエステル受容体 / ジアシルグリセロール / ホルボールエメテル / Phorbol ester receptor / Phospholipid / Diacylglycerol / 上皮菅腔組織形成 / 菅腔生物学 / 国際シンポジウム / 総括班 / 管腔生物学 / 上皮管腔組織形成 / ホームページ / 計画研究 / ニュースレター / aPKC / 毛包新生 / 細胞移動 / Wnt経路 / 休眠機構 Less

Regulatory mechanism of hair follicle stem cell quiescence by cell polariry protein aPKC
- Principal Investigator
  
  OSADA Shin-Ichi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Akita University
Mechanism for the maintenance of skin stem cells by a cell polarity protein
- Principal Investigator
  
  OSADA Shin-Ichi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Akita University
  Nippon Medical School
Regulation of cell polarity and cell fates in tissue stem/progenitor cellsPrincipal Investigator
- Principal Investigator
  
  OHNO Shigeo
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Yokohama City University
Nephrin cycle : Analyses of the dynamic state of the podocyte slit diaphragm proteins in vivo and in vitroPrincipal Investigator
- Principal Investigator
  
  OHNO Shigeo
- Project Period (FY)
  2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Yokohama City University
Regulation of polarity signaling during morphogenesis, remodeling, and breakdown of epithelial tubular structure
- Principal Investigator
  
  Kikuchi Akira
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Molecular mechanisms of the polarity-regulating signalingPrincipal Investigator
- Principal Investigator
  
  OHNO Shigeo
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Cell biology
- Research Institution
  Yokohama City University
Cell Polarity Signaling and CancerPrincipal Investigator
- Principal Investigator
  
  OHNO Shigeo
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Yokohama City University
Molecular mechanism of mammalian mRNA surveillancePrincipal Investigator
- Principal Investigator
  
  OHNO Shigeo
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General medical chemistry
- Research Institution
  Yokohama City University
Disorganization of cell and tissue systems in cancer
- Principal Investigator
  
  TAKAI Yoshimi
- Project Period (FY)
  2004 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
  Osaka University
ナンセンスmRNA分解系の特異的な抑制による変異遺伝子機能回復の可能性の検討Principal Investigator
- Principal Investigator
  
  大野茂男
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Human genetics
- Research Institution
  Yokohama City University
Molecular mechanism of mammalian mRNA surveillancePrincipal Investigator
- Principal Investigator
  
  OHNO Shigeo
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General medical chemistry
- Research Institution
  Yokohama City University Graduate School of Medical Science
ナンセンスmRNA分解系の特異的な抑制による変異遺伝子機能回復の可能性の検討Principal Investigator
- Principal Investigator
  
  大野茂男
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Human genetics
- Research Institution
  Yokohama City University
Molecular mechanism of mammalian mRNA surveillancePrincipal Investigator
- Principal Investigator
  
  OHNO Shigeo
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Yokohama City University
Signaling mechanism of epithelial cell-cell attachment and cell polarity.Principal Investigator
- Principal Investigator
  
  OHNO Shigeo
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Yokohama City University
脊髄動物の初期胚におけるPAR及びaPKCの動態と極性の決定機構Principal Investigator
- Principal Investigator
  
  大野茂男
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Yokohama City University
Analyses of the universal molecular machinary involved in cell polarizationPrincipal Investigator
- Principal Investigator
  
  OHNO Shigeo
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Functional biochemistry
- Research Institution
  Yokohama City University School of Medicine
ヒッペル・リンドウ病の遺伝子診断に関する国際間交流研究
- Principal Investigator
  
  SHUIN Tarou
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  Urology
- Research Institution
  高知医科大学
血管内皮細胞の細胞間相互作用とPKCPrincipal Investigator
- Principal Investigator
  
  大野茂男
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Yokohama City University
Intra-cellular signaling cascades involved in cellular stress responsesPrincipal Investigator
- Principal Investigator
  
  OHNO Shigeo
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Yokohama City University School of Medicine
VHL tumor suppressor gene : Identification its function for cell growth inhibition and cell ular apoptosis for kidne cancer to develop new modality of treatment
- Principal Investigator
  
  SHUIN Taro
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Kochi Medical School
Analysis of sinnalling pathway of apoptosis degradation using PKCδ gene-targeting mice
- Principal Investigator
  
  NAKAYAMA Kei-ichi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Molecular biology
- Research Institution
  Kyushu University
Manipulation of the interaction between protein kinase C and its specific substrate proteinsPrincipal Investigator
- Principal Investigator
  
  OHNO Shigeo
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Yokohama City University School of Medicine
細胞接着と細胞増殖におけるC-キナーゼの役割Principal Investigator
- Principal Investigator
  
  大野茂男
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Yokohama City University
炎症起因物質の放出過程におけるCキナーゼ分子種の役割と作用機構に関する研究
- Principal Investigator
  
  秋田朗子
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
International study of von Hippel-Lindau disease
- Principal Investigator
  
  SHUIN Tarou
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Kochi Meidcal School
Study on the PKC isozymes-mediated mechanism in the regulated secretion.
- Principal Investigator
  
  AKITA Yoshiko
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内分泌・代謝学
- Research Institution
  The Tokyo Metropolitan Institute of Medical Science
Cooperation and information exchange with European countries.
- Principal Investigator
  
  KUROKI Toshio
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Showa University
  The University of Tokyo
Role of three dimensional structure of proteins in signal transduction
- Principal Investigator
  
  INAGAKI Fuyuhiko
- Project Period (FY)
  1994 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
Study on the roles of protein kinase Cisozymes in hormonal secretory process.
- Principal Investigator
  
  AKITA Yoshiko
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内分泌・代謝学
- Research Institution
  The Tokyo Metropolitan Institute of Medical Science
細胞増殖におけるプロテインキナーゼC群の機能の分子生物学的解析Principal Investigator
- Principal Investigator
  
  大野茂男
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Yokohama City University
Action mechanisms of dominant negative protein kinase C ; identification of PKC binding proteinsPrincipal Investigator
- Principal Investigator
  
  OHNO Shigeo
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Yokohama City University
細胞増殖におけるプロテインキナ-ゼC群の機能の分子生物学的解析Principal Investigator
- Principal Investigator
  
  大野茂男
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Yokohama City University
  Tokyo Metropolitan Organization for Medical Research
Identification and Functional Analysis of Protein Kinase C-Related GenePrincipal Investigator
- Principal Investigator
  
  OHNO Shigeo
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  YOKOHAMA CITY UNIVERSITY SCHOOL OF MEDICINE
Functional Domains on Human Platelet Glycoprotein IIb/IIIa.
- Principal Investigator
  
  TANOUE Kenjiro
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Tokyo Metropolitan Institute of Medical Science.
Study on the roles of protein kinase C isozymes in stimulus-responses
- Principal Investigator
  
  AKITA Yoshiko
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  代謝生物化学
- Research Institution
  The Tokyo Metropolitan Institute of Medical Science
細胞増殖におけるプロティンキナ-ゼC群の機能の分子生物学的研究Principal Investigator
- Principal Investigator
  
  大野茂男
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
プロテインキナ-ゼC群の分子多様性及びその構造と機能の分子生物学的解析Principal Investigator
- Principal Investigator
  
  大野茂男
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
Function of Calcium-Dependent Protease in Down Regulation of Protein Dinase C
- Principal Investigator
  
  SUZUKI Koichi
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  物質生物化学
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
細胞増殖におけるプロテインキナーゼCの機能の分子生物学的研究Principal Investigator
- Principal Investigator
  
  大野茂男
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
Cooperation and Information Exchange with European Countries
- Principal Investigator
  
  KUROKI Toshio
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Institute of Medical Science, University of Tokyo
Study of the roles of protein kinase C isozymes in the signal transduction
- Principal Investigator
  
  AKITA Yoshiko
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  物質生物化学
- Research Institution
  The Tokyo Metropolitan Institute of Medical Science
クロマチン・レベルの制御シグナル
- Principal Investigator
  
  岩淵雅樹
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Hokkaido University
カルシウム依存性プロテアーゼのドメイン構造と活性の発現制御
- Principal Investigator
  
  鈴木紘一
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  物質生物化学
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
cDNA cloning of thrombin-receptor on platelet membrane glycoprotein Ib.
- Principal Investigator
  
  TANOUE Kenjiro
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
クロマチン・レベルの制御シグナル
- Principal Investigator
  
  村松正実
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  The University of Tokyo

[Book] Cell Polarity 1 Biological Role and Basic Mechanisms(The PAR3-aPKC-PAR6 Complex)2015
- Author(s)
  Ohno S, Goulas S, Hirose T
- Total Pages
  11
- Publisher
  Springer
- Data Source
  KAKENHI-PLANNED-23112003
[Book] 医学のあゆみ(細胞極性制御因子とHippoシグナルの接点)2014
- Author(s)
  山下和成, 大野茂男
- Total Pages
  6
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PLANNED-23112003
[Book] 生化学・第2版2007
- Author(s)
  大野茂男
- Total Pages
  217
- Publisher
  東京化学同人
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] Regulation of Asymmetric Division by Atypical Protein Kinase C Influences Early Specification of CD8(+) T Lymphocyte Fates.2016
- Author(s)
  Metz P. J, Lopez J, Kim S. H, Akimoto K, Ohno S, Chang J. T
- Journal Title
  
  Sci Rep
  
  Volume: 6 Pages: 19182-19182
- DOI
  10.1038/srep19182
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23112003
[Journal Article] Aberrant Expression of the Cell Polarity Regulator aPKClambda/iota is Associated With Disease Progression in Cervical Intraepithelial Neoplasia (CIN): A Possible Marker for Predicting CIN Prognosis.2016
- Author(s)
  Mizushima T, Asai-Sato M, Akimoto K, Nagashima Y, Taguri M, Sasaki K, Nakaya M. A, Asano R, Tokinaga A, Kiyono T, Hirahara F, Ohno S, Miyagi E
- Journal Title
  
  Int J Gynecol Pathol
  
  Volume: 35 Pages: 106-17
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23112003
[Journal Article] Atypical protein kinase C isoform, aPKCλ, is Essential for Maintaining Hair Follicle Stem Cell Quiescence2015
- Author(s)
  Shin-Ichi Osada, Naoko Minematsu, Fumino Oda, Kazunori Akimoto, Seiji Kawana and Shigeo Ohno
- Journal Title
  
  J Invest Dermatol
  
  Volume: 未定
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24591669
[Journal Article] Aberrant activation of atypical protein kinase C in carbon tetrachloride-induced oxidative stress provokes a disturbance of cell polarity and sealing of bile canalicular lumen.2015
- Author(s)
  Horikoshi Y, Kitatani K, Toriumi K, Fukunishi N, Itoh Y, Nakamura N, Ohno S, Matsura T, Takekoshi S
- Journal Title
  
  Am J Pathol
  
  Volume: 185 Pages: 958-968
- DOI
  10.1016/j.ajpath.2014.12.015
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23112003
[Journal Article] Regulation of Asymmetric Division and CD8+ T Lymphocyte Fate Specification by Protein Kinase Czeta and Protein Kinase Clambda/iota.2015
- Author(s)
  Metz P. J, Arsenio J, Kakaradov B, Kim S. H, Remedios K. A, Oakley K, Akimoto K, Ohno S, Yeo G. W, Chang J. T
- Journal Title
  
  J Immunol
  
  Volume: 194 Pages: 2249-2259
- DOI
  10.4049/jimmunol.1401652
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23112003
[Journal Article] The PAR3-aPKC Complex2015
- Author(s)
  Ohno, S., Goulas, S. and Hirose, T.
- Journal Title
  
  Cell Polarity, K. Ebnet. Switzerland, Springer International Publishing
  
  Volume: 1 Pages: 3-23
- DOI
  10.1007/978-3-319-14463-4_1
- Data Source
  KAKENHI-PLANNED-23112003
[Journal Article] 細胞極性制御因子とHippoシグナルの接点.2015
- Author(s)
  山下和成, 大野茂男
- Journal Title
  
  別冊・医学のあゆみ　広がるHippo pathway研究-癌から各種疾患へ
  
  Volume: なし Pages: 7-12
- Data Source
  KAKENHI-PLANNED-23112003
[Journal Article] Regulation of epithelial cell polarity by PAR-3 depends on Girdin transcription and Girdin-Galphai3 signaling.2015
- Author(s)
  Sasaki K, Kakuwa T, Akimoto K, Koga H, Ohno S
- Journal Title
  
  J Cell Sci
  
  Volume: 128 Pages: 2244-58
- DOI
  10.1242/jcs.160879
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-23112003
[Journal Article] Tumor suppressor protein Lgl mediates G1 cell cycle arrest at high cell density by forming an Lgl-VprBP-DDB1 complex.2015
- Author(s)
  Yamashita K, Ide M, Furukawa K. T, Suzuki A, Hirano H, Ohno S
- Journal Title
  
  Mol Biol Cell
  
  Volume: 26 Pages: 2426-38
- DOI
  10.1091/mbc.e14-10-1462
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-23112003
[Journal Article] Atypical Protein Kinase C Isoform, aPKClambda, Is Essential for Maintaining Hair Follicle Stem Cell Quiescence.2015
- Author(s)
  Osada S, Minematsu N, Oda F, Akimoto K, Kawana S, Ohno S
- Journal Title
  
  J Invest Dermatol
  
  Volume: 135 Pages: 2584-2592
- DOI
  10.1038/jid.2015.222
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09755, KAKENHI-PLANNED-23112003
[Journal Article] MTCL1 crosslinks and stabilizes non-centrosomal microtubules on the Golgi membrane.2014
- Author(s)
  Yoshinori Sato, Kenji Hayashi, Yoshiko Amano, Mikiko Takahashi, Shigenobu Yonemura, Ikuko Hayashi, Hiroko Hirose, Shigeo Ohno, Atsushi Suzuki
- Journal Title
  
  Nat Commun
  
  Volume: 5:5266 Pages: 1-14
- DOI
  10.1038/ncomms6266
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-14J09939, KAKENHI-PLANNED-23112003
[Journal Article] Loss of aPKCλ in differentiated neurons disrupts the polarity complex but does not induce obvious neuronal loss or disorientation in mouse brains.2014
- Author(s)
  Yamanaka, T., Tosaki, A., Kurosawa, M., Akimoto, K., Hirose, T., Ohno, S., Hattori, N. & Nukina, N.
- Journal Title
  
  PLoS One
  
  Volume: 8
- DOI
  10.1371/journal.pone.0084036
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22110004, KAKENHI-PLANNED-23112003, KAKENHI-PROJECT-23700430, KAKENHI-PUBLICLY-24111553, KAKENHI-PROJECT-24659436
[Journal Article] Colorectal laterally spreading tumors show characteristic expression of cell polarity factors, including atypical protein kinase C lambda/iota, E-cadherin, beta-catenin and basement membrane component.2014
- Author(s)
  chikawa Y, Nagashima Y, Morioka K, Akimoto K, Kojima Y, Ishikawa T, Goto A, Kobayashi N, Watanabe K, Ota M, Fujii S, Kawamata M, Takagawa R, Kunizaki C, Takahashi H, Nakajima A, Maeda S, Shimada H, Inayama Y, Ohno S, Endo I
- Journal Title
  
  Oncol Lett
  
  Volume: 8 Pages: 977-984
- DOI
  10.3892/ol.2014.2271
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23112003
[Journal Article] The phosphorylation of HIV-1 Gag by atypical protein kinase C facilitates viral infectivity by promoting Vpr incorporation into virions2014
- Author(s)
  Kudoh A, Takahama S, Sawasaki T, Ode H, Yokoyama M, Okayama A, Ishikawa A, Miyakawa K, Matsunaga S, Kimura H, Sugiura W, Sato H, Hirano H, Ohno S, Yamamoto N, Ryo A
- Journal Title
  
  Retrovirology.
  
  Volume: 11 Pages: 9-9
- DOI
  10.1186/1742-4690-11-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-23112003, KAKENHI-PROJECT-24390115, KAKENHI-PROJECT-24790447
[Journal Article] aPKCλ maintains the integrity of the glomerular slit diaphragm through trafficking of nephrin to the cell surface2014
- Author(s)
  Satoh D, Hirose T, Harita Y, Daimon C, Harada T, Kurihara H, Yamashita A, Ohno S.
- Journal Title
  
  J Biochem
  
  Volume: 156(2) Pages: 115-126
- DOI
  10.1093/jb/mvu022
- NAID
  40020155095
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-21115004, KAKENHI-PROJECT-23687025, KAKENHI-PROJECT-24390259, KAKENHI-PROJECT-24591214, KAKENHI-PROJECT-25461617, KAKENHI-PLANNED-23112003
[Journal Article] 2) A novel PAR-1-binding protein, MTCL1, plays critical roles in organizing microtubules in polarizing epithelial cells.2013
- Author(s)
  Sato Y, Akitsu M, Amano Y, Yamashita K, Ide M, Shimada K, Yamashita A, Hirano H, Arakawa N, Maki T, Hayashi I, Ohno S, Suzuki A.
- Journal Title
  
  J Cell Sci
  
  Volume: 126(Pt 20) Pages: 4671-4683
- DOI
  10.1242/jcs.127845
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-21115004, KAKENHI-PLANNED-21116004, KAKENHI-PLANNED-23112003, KAKENHI-PROJECT-23687025, KAKENHI-PROJECT-25460695
[Journal Article] Inhibition of SMG-8, a subunit of SMG-1, ameliorates the mutant phenotype exacerbated by nonsense-mediated mRNA decay without cytotoxicity.2013
- Author(s)
  Usuki F, Yamashita A, Shiraishi T, Shiga A, Onodera O, Higuchi I, Ohno S
- Journal Title
  
  Proc Natl Acad Sci
  
  Volume: 110 Pages: 15037-15042
- DOI
  10.1073/pnas.1300654110
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-23112003, KAKENHI-PROJECT-23687025, KAKENHI-PROJECT-25460402
[Journal Article] aPKCλ/ι is a beneficial prognostic marker for pancreatic neoplasms2013
- Author(s)
  Kato S, Akimoto K, Nagashima Y, Ishiguro H, Kubota K, Kobayashi N, Hosono K, Watanabe S, Sekino Y, Sato T, Sasaki K, Nakaigawa N, Kubota Y, Inayama Y, Endo I, Ohno S, Maeda S, Nakajima A
- Journal Title
  
  Pancreatology
  
  Volume: 13 Pages: 360-8
- DOI
  10.1016/j.pan.2013.05.006
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23112003, KAKENHI-PROJECT-23590429, KAKENHI-PROJECT-24790714
[Journal Article] Conditionally replicative adenoviral vectors for imaging the effect of chemotherapy on pancreatic cancer cells.2013
- Author(s)
  Kimura J, Ono H. A, Kosaka T, Nagashima Y, Hirai S, Ohno S, Aoki K, Julia D, Yamamoto M, Kunisaki C, Endo I
- Journal Title
  
  Cancer Sci
  
  Volume: 104 Pages: 1083-1090
- DOI
  10.1111/cas.12196
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23112003, KAKENHI-PROJECT-23590429
[Journal Article] Spatial regulation of VEGF receptor endocytosis in angiogenesis.2013
- Author(s)
  Nakayama, M.
- Journal Title
  
  endocytosis in angiogenesis. Nat Cell Biol
  
  Volume: 15 Pages: 249-260
- DOI
  10.1038/ncb2679
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20227006, KAKENHI-PROJECT-22247030, KAKENHI-PLANNED-23112003, KAKENHI-PROJECT-23790342, KAKENHI-PUBLICLY-23123518
[Journal Article] Polarity-dependent distribution of angiomotin localizes Hippo signaling in preimplantation embryos2013
- Author(s)
  Hirate Y, Hirahara S, Inoue K-i, Suzuki A, Alarcon VB, Akimoto K, Hirai T, Hara T, Adachi M, Chida K, Ohno S, Marikawa Y, Nakao K, Shimono A, Sasaki H
- Journal Title
  
  Curr Biol.
  
  Volume: 23 Pages: 1181-1194
- DOI
  10.1016/j.cub.2013.05.014
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-21116003, KAKENHI-PLANNED-21116004, KAKENHI-PLANNED-23112003, KAKENHI-PROJECT-23247036, KAKENHI-PROJECT-25440112, KAKENHI-PROJECT-25460362
[Journal Article] The interaction of Kinesin-1 with its adaptor protein JIP1 can be regulated via proteins binding to the JIP1-PTB domain2013
- Author(s)
  Satake T, et al.
- Journal Title
  
  BMC Cell Biol
  
  Volume: 14 Pages: 12-12
- DOI
  10.1186/1471-2121-14-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570184, KAKENHI-PROJECT-22247030, KAKENHI-PLANNED-23112003
[Journal Article] High expression of KIBRA in low aPKC-expressing gastric cancer correlates with lymphatic invasion and poor prognosis.2013
- Author(s)
  Y. Yoshihama, Y. Izumisawa, K. Akimoto, Y. Satoh, T. Mizushima, K. Satoh, K. Chida, R. Takagawa, H. Akiyama, Y. Ichikawa, C. Kunisaki, Y. Inayama, I. Endo, Y. Nagashima and S. Ohno
- Journal Title
  
  Cancer Sci
  
  Volume: 104 Pages: 259-265
- DOI
  10.1111/cas.12066
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22247030, KAKENHI-PLANNED-23112003, KAKENHI-PROJECT-23590429
[Journal Article] Analysis of interferon-beta mRNA stability control after poly(I : C) stimulation using RNA metabolic labeling by ethynyluridine2012
- Author(s)
  Abe K, Ishigami T, Shyu A. B, Ohno S, Umemura S, Yamashita A
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 428(1) Pages: 44-49
- DOI
  10.1016/j.bbrc.2012.09.144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22247030, KAKENHI-PROJECT-23591221, KAKENHI-PROJECT-23687025, KAKENHI-PUBLICLY-23112718, KAKENHI-PLANNED-21115004
[Journal Article] Integrated regulation of PIKK-mediated stress responses by AAA+ proteins RUVBL1 and RUVBL22012
- Author(s)
  Izumi N, Yamashita A and Ohno S
- Journal Title
  
  Nucleus
  
  Volume: 3 Pages: 29-43
- DOI
  10.4161/nucl.18926
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22247030, KAKENHI-PUBLICLY-23112718, KAKENHI-PROJECT-23687025
[Journal Article] PAR-1/MARK: a kinase essential for maintaining the dynamic state of microtubules.2012
- Author(s)
  Hayashi K, Suzuki A, Ohno S
- Journal Title
  
  Cell Struct Funct
  
  Volume: 37(1) Pages: 21-25
- NAID
  130004053887
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22247030
[Journal Article] PAR-1/MARK: a kinase essential for maintaining the dynamic state of microtubules2012
- Author(s)
  Hayashi K, Suzuki A and Ohno S
- Journal Title
  
  Cell Struct Funct
  
  Volume: 37 Pages: 21-5
- NAID
  130004053887
- URL
  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=22139392
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22247030
[Journal Article] N- and C-terminal Upfl phosphorylations create binding platforms for SMG-6 and SMG-5:SMG-7 during NMD2012
- Author(s)
  Okada-Katsuhata Y, Yamashita A, Kutsuzawa K, Izumi N, Hirahara F, Ohno S
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: 40 Pages: 1251-1251
- DOI
  10.1093/nar/gkr791
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J02706, KAKENHI-PLANNED-21115004, KAKENHI-PROJECT-22247030, KAKENHI-PLANNED-23112003, KAKENHI-PUBLICLY-23112718, KAKENHI-PROJECT-23687025
[Journal Article] Integrated regulation of PIKK-mediated stress responses by AAA+ proteins RUVBL1 and RUVBL2.2012
- Author(s)
  Izumi N, Yamashita A, Ohno S
- Journal Title
  
  Nucleus
  
  Volume: 3(1) Pages: 29-43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22247030
[Journal Article] Tumor type-dependent function of the par3 polarity protein in skin tumorigenesis.2012
- Author(s)
  S. Iden, W. E. van Riel, R. Schafer, J. Y. Song, T. Hirose, S. Ohno and J. G. Collard
- Journal Title
  
  Cancer Cell.
  
  Volume: 22 Pages: 389-403
- DOI
  10.1016/j.ccr.2012.08.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22247030, KAKENHI-PLANNED-23112003, KAKENHI-PROJECT-23790342, KAKENHI-PUBLICLY-23123518
[Journal Article] Heat shock protein 90 regulates phosphatidylinositol 3-kinase-related protein kinase family proteins together with the RUVBL1/2 and Tel2-containing co-factor complex.2012
- Author(s)
  Izumi N, Yamashita A, Hirano H, Ohno S
- Journal Title
  
  Cancer Sci.
  
  Volume: 103 Pages: 50-57
- DOI
  10.1111/j.1349-7006.2011.02112.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J02706, KAKENHI-PLANNED-21115004, KAKENHI-PROJECT-22247030, KAKENHI-PLANNED-23112003, KAKENHI-PUBLICLY-23112718, KAKENHI-PROJECT-23687025
[Journal Article] PAR-1/MARK: a kinase essential for maintaining the dynamic state of microtubules.2012
- Author(s)
  Hayashi K, Suzuki A, Ohno S
- Journal Title
  
  Cell Struct Funct
  
  Volume: 37(1) Pages: 21-25
- NAID
  130004053887
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23112003
[Journal Article] Regulation of the alternative splicing of sarcoplasmic reticulum Ca(2)(+)-ATPase1 (SERCA1) by phorbol 12-myristate 13-acetate (PMA) via a PKC pathway.2012
- Author(s)
  Zhao Y, Koebis M, Suo S, Ohno S, Ishiura S.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 423 Pages: 212-217
- DOI
  10.1016/j.bbrc.2012.05.033
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J08975, KAKENHI-PROJECT-22247030
[Journal Article] Integrated regulation of PIKK-mediated stress responses by AAA+ proteins RUVBL1 and RUVBL2.2012
- Author(s)
  Izumi N, Yamashita A, Ohno S
- Journal Title
  
  Nucleus
  
  Volume: 3(1) Pages: 29-43
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23112003
[Journal Article] The KIBRA-aPKC connection: A potential regulator of membrane trafficking and cell polarity.2012
- Author(s)
  Y. Yoshihama, K. Chida and S. Ohno
- Journal Title
  
  Commun Integr Biol
  
  Volume: 5 Pages: 146-151
- DOI
  10.4161/cib.18849
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22247030, KAKENHI-PLANNED-23112003
[Journal Article] Axon formation in neocortical neurons depends on stage-specific regulation of microtubule stability by the DLK-JNK pathway.2011
- Author(s)
  Hirai S-I, Banba Y, Satake T, Ohno S
- Journal Title
  
  J. Neuroscience
  
  Volume: 31(17) Pages: 6468-6480
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23112003
[Journal Article] The nonsense-mediated mRNA decay SMG-1 kinase is regulated by large-scale conformational changes controlled by SMG-8.2011
- Author(s)
  Arias-Palomo E, Yamashita A, Fernandez IS, Nunez-Ramirez R, Bamba Y, Izumi N, Ohno S, Llorca O.
- Journal Title
  
  Genes Dev.
  
  Volume: 25(2) Pages: 153-164
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22247030
[Journal Article] KIBRA Suppresses Apical Exocytosis through Inhibition of aPKC Kinase Activity in Epithelial Cells.2011
- Author(s)
  Yoshihama Y, Sasaki K , Horikoshi Y, Suzuki A, Ohtsuka T, Hakuno F, Takahashi S-I, Ohno S, Chida K
- Journal Title
  
  Current Biol.
  
  Volume: 21(8) Pages: 705-711
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22247030
[Journal Article] KIBRA Suppresses Apical Exocytosis through Inhibition of aPKC Kinase Activity in Epithelial Cells2011
- Author(s)
  Yoshihama Y, Sasaki K, Horikoshi Y, Suzuki A, Ohtsuka T, Hakuno F, Takahashi S-I, Ohno S, Chida K
- Journal Title
  
  Current Biol.
  
  Volume: 21 Pages: 705-711
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659174
[Journal Article] The co-expression of aPKCλ/ι and IL-6 in prostate cancer tissue correlates with biochemical recurrence.2011
- Author(s)
  Ishiguro H, Akimoto K, Nagashima Y, Kagawa E, Sasaki T, Sano J, Takagawa R, Fujinami K, Sasaki K, Aoki I, Ohno S
- Journal Title
  
  Cancer Science
  
  Volume: 102(8) Pages: 1576-1581
- NAID
  10030242512
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23112003
[Journal Article] Phosphoinositide binding by par-3 involved in par-3 localization.2011
- Author(s)
  Horikoshi Y, Hamada S, Ohno S, Suetsugu S
- Journal Title
  
  Cell Structure and Function
  
  Volume: 36(1) Pages: 97-102
- NAID
  40019163941
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22247030
[Journal Article] Characterization of SMG-9, an essential component of the nonsense-mediated mRNA decay. SMG1C complex.2011
- Author(s)
  Fernandez IS, Yamashita A, Arias-Palomo E, Bamba Y, Bartolome RA, Canales MA, Teixido J, Ohno S, Llorca O
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: 39(1) Pages: 347-358
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22247030
[Journal Article] The co-expression of aPKCλ/ι and IL-6 in prostate cancer tissue correlates with biochemical recurrence.2011
- Author(s)
  Ishiguro H, Akimoto K, Nagashima Y, Kagawa E, Sasaki T, Sano J, Takagawa R, Fujinami K, Sasaki K, Aoki I, Ohno S, Kubota Y, Uemura H
- Journal Title
  
  Cancer Science
  
  Volume: 102(8) Pages: 1576-1581
- NAID
  10030242512
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22247030
[Journal Article] Co-expression of atypical protein kinase C l/i and interleukin-6 in prostate cancer tissue correlates with biochemical recurrence.2011
- Author(s)
  Ishiguro H, Akimoto K, Nagashima Y, Kagawa E, Sasaki T, Sano J, Takagawa R, Fujinami K, Sasaki K, Aoki I, Ohno S, Kubota Y and Uemura H
- Journal Title
  
  Cancer Sciience
  
  Volume: 102 Pages: 1576-1581
- DOI
  10.1111/j.1349-7006.2011.01972.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22247030, KAKENHI-PROJECT-23590429, KAKENHI-PROJECT-23791798
[Journal Article] A novel role for hSMG-1 in stress granule formation.2011
- Author(s)
  Brown J A, Roberts T L, Richards R, Woods R, Birrell G, Lim YC, Ohno S, Yamashita A, Abraham RT, Gueven N, Lavin MF
- Journal Title
  
  Mol Cell Biol
  
  Volume: 31(22) Pages: 4417-4429
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23112003
[Journal Article] Phosphoinositide binding by par-3 involved in par-3 localization2011
- Author(s)
  Horikoshi Y, Hamada S, Ohno S and Suetsugu S:
- Journal Title
  
  Cell Structure and Function
  
  Volume: 36 Pages: 97-102
- NAID
  40019163941
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/21467691
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22247030
[Journal Article] Axon formation in neocortical neurons depends on stage-specific regulation of microtubule stability by the DLK-JNK pathway.2011
- Author(s)
  Hirai S-I, Banba Y, Satake T, Ohno S
- Journal Title
  
  J. Neuroscience
  
  Volume: 31(17) Pages: 6468-6480
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22247030
[Journal Article] Axon formation in neocortical neurons depends on stage-specific regulation of microtubule stability by the DLK-JNK pathway2011
- Author(s)
  Hirai S-I, Banba Y, Satake T and Ohno S:
- Journal Title
  
  J. Neuroscience
  
  Volume: 3 Pages: 6468-6480
- DOI
  10.1523/jneurosci.5038-10.2011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22247030
[Journal Article] Phosphoinositide binding by par-3 involved in par-3 localization.2011
- Author(s)
  Horikoshi Y, Hamada S, Ohno S, Suetsugu S
- Journal Title
  
  Cell Structure and Function
  
  Volume: 36(1) Pages: 97-102
- NAID
  40019163941
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23112003
[Journal Article] A novel role for hSMG-1 in stress granule formation.2011
- Author(s)
  Brown J A, Roberts T L, Richards R, Woods R, Birrell G, Lim YC, Ohno S, Yamashita A, Abraham RT, Gueven N, Lavin MF
- Journal Title
  
  Mol Cell Biol
  
  Volume: 31(22) Pages: 4417-4429
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22247030
[Journal Article] KIBRA Suppresses Apical Exocytosis through Inhibition of aPKC Kinase Activity in Epithelial Cells2011
- Author(s)
  Yoshihama Y, Sasaki K, Horikoshi Y, Suzuki A, Ohtsuka T, Hakuno F, Takahashi S-I, Ohno S, Chida K
- Journal Title
  
  Current Biol
  
  Volume: 21(8) Pages: 705-711
- URL
  http://www.ncbi.nlm.nih.gov/pubmed?term=21497093
- Data Source
  KAKENHI-PROJECT-23659174
[Journal Article] Maintenance of dendritic spine morphology by partitioning-defective 1b through regulation of microtubule growth.2011
- Author(s)
  Hayashi K, Suzuki A, Hirai S, Kurihara Y, Hoogenraad CC, Ohno S
- Journal Title
  
  J Neurosci
  
  Volume: 31(34) Pages: 12094-12103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22247030
[Journal Article] Maintenance of dendritic spine morphology by partitioning-defective 1b through regulation of microtubulegrowthJ Neurosci2011
- Author(s)
  Hayashi K, Suzuki A, Hirai S, Kurihara Y, Hoogenraad CC, Ohno S
- Journal Title
  
  J Neurosci
  
  Volume: 31 Pages: 12094-12103
- DOI
  10.1523/jneurosci.0751-11.2011
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21116004, KAKENHI-PROJECT-21570184, KAKENHI-PROJECT-22247030
[Journal Article] KIBRA Suppresses Apical Exocytosis through Inhibition of aPKC Kinase Activity in Epithelial Cells.2011
- Author(s)
  Yoshihama Y, Sasaki K, Horikoshi Y, Suzuki A, Ohtsuka T, Hakuno F, Takahashi S-I, Ohno S, Chida K
- Journal Title
  
  Current Biol
  
  Volume: 21 Pages: 1-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22247030
[Journal Article] Axon Formation in Neocortical Neurons Depends on Stage-Specific Regulation of Microtubule Stability by the Dual Leucine Zipper Kinase-c-Jun N-terminal Kinase Pathway.2011
- Author(s)
  Hirai S, Banba Y, Satake T, Ohno S
- Journal Title
  
  J Neuroscience
  
  Volume: 31(17) Pages: 6468-6480
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22247030
[Journal Article] KIBRA Suppresses Apical Exocytosis through Inhibition of aPKC Kinase Activity in Epithelial Cells2011
- Author(s)
  Yohei Yoshihama
- Journal Title
  
  Curr Biol
  
  Volume: 21 Pages: 705-711
- DOI
  10.1016/j.cub.2011.03.029
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-09J05317, KAKENHI-PLANNED-21116004, KAKENHI-PROJECT-21580345, KAKENHI-PROJECT-22247030, KAKENHI-PROJECT-23790379
[Journal Article] Maintenance of dendritic spine morphology by partitioning-defective 1b through regulation of microtubule growth.2011
- Author(s)
  Hayashi K, Suzuki A, Hirai S, Kurihara Y, Hoogenraad CC, Ohno S
- Journal Title
  
  J Neurosci
  
  Volume: 31(34) Pages: 12094-12103
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23112003
[Journal Article] KIBRA Suppresses Apical Exocytosis through Inhibition of aPKC Kinase Activity in Epithelial Cells. Current Biol.2011
- Author(s)
  Yoshihama Y, Sasaki K , Horikoshi Y, Suzuki A, Ohtsuka T, Hakuno F, Takahashi S-I, Ohno S, Chida K
- Journal Title
  
  Current Biol
  
  Volume: 21(8) Pages: 705-711
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23112003
[Journal Article] Analysis of Nonsense-Mediated mRNA Decay by Monitoring mRNA Half-Lives in Mammalian Cells.2010
- Author(s)
  Yamashita A, Ohno S
- Journal Title
  
  Cold Spring Harbor Protocols
  
  Volume: (2)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22247030
[Journal Article] AAA+ proteins RUVBL1 and RUVBL2 coordinate PIKK family and function in nonsense-mediated mRNA decay.2010
- Author(s)
  Izumi N, Yamashita A, Iwamatsu A, Kurata R, Nakamura H, Saari B, Hirano H, Anderson P, Ohno S
- Journal Title
  
  Science Signaling 3(116)
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] ASPP2 regulates epithelial cell polarity through the PAR complex.2010
- Author(s)
  Cong W, Hirose T, Harita Y, Yamashita A, Mizuno K, Hirano H, Ohno S
- Journal Title
  
  Curr.Biol.
  
  Volume: 20(15) Pages: 1408-1414
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22247030
[Journal Article] The 8th and 9th tandem spectrin-like repeats of utrophin cooperatively form a functional unit to interact with polarity-regulating kinase PAR-1b.2010
- Author(s)
  Yamashita K, Suzuki A, Satoh Y, Ide M, Amano Y, Masuda-Hirata M, Hayashi Y.K, Hamada K, Ogata K, Ohno S
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 391(1) Pages: 812-817
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22247030
[Journal Article] AAA+ proteins RUVBL1 and RUVBL2 coordinate PIKK family and function in nonsense-mediated mRNA decay.2010
- Author(s)
  Izumi N, Yamashita A, Iwamatsu A, Kurata R, Nakamura H, Saari B, Hirano H, Anderson P, Ohno S
- Journal Title
  
  Science Signaling
  
  Volume: 3(116)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22247030
[Journal Article] AAA+ proteins RUVBL1 and RUVBL2 coordinate PIKK family and function in nonsense-mediated Mrna decay.2010
- Author(s)
  Inumi N, Yamashita A, Iwamatsu A, Kurata R, Nakamura H, Saari B, Hirano H, Anderson P, Ohno S
- Journal Title
  
  Science Signaling 3(116)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] ASPP2 regulates epithelial cell polarity through the PAR complex2010
- Author(s)
  Cong W, Hirose T, Harita Y, Yamashita A, Mizuno K, Hirano H and Ohno S
- Journal Title
  
  Curr Biol
  
  Volume: 20 Pages: 1408-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22247030
[Journal Article] AAA+ proteins RUVBL1 and RUVBL2 coordinate PIKK activity and function in nonsense-mediated mRNA decay2010
- Author(s)
  Izumi N, Yamashita A, Iwamatsu A, Kurata R, Nakamura H, Saari B, HiranoH, Anderson P and Ohno S
- Journal Title
  
  Sci Signal
  
  Volume: 116 Pages: 27-27
- DOI
  10.1126/scisignal.2000468
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22247030
[Journal Article] Intracellular polarity protein PAR-1 regulates extracellular laminin assembly by regulating the dystroglycan Complex2009
- Author(s)
  Masuda-Hirata M, Suzuki A, Amano Y, Yamashita K, Ide M, Yamanaka T, Sakai M, Imamura Mand Ohno S
- Journal Title
  
  Genes to Cells (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] aPKClambda/iota promotes growth of prostate cancer cells in an autocrine manner through transcriptional activation of interleukin-6.2009
- Author(s)
  Ishiguro H, Akimoto K, Nagashima Y, Kojima Y, Sasaki T, Ishiguro-Imagawa Y, Nakaigawa N, Ohno S, Kubota Y, Uemura H
- Journal Title
  
  Proc Natl Acad Sci USA 106(38)
  
  Pages: 16369-16374
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] aPKCλ/ιpromotes growth of prostate cancer cells in an autocrine manner through transcriptional activation of interleukin-6.2009
- Author(s)
  Ishiguro H, Akimoto K, Nagashima Y, Kojima Y, Sasaki T, Ishiguro-Imagawa Y, Nakaigawa N, Ohno S, Kubota Y, Uemura H.
- Journal Title
  
  Proc Natl Acad Sci USA. 106(38)
  
  Pages: 16369-16374
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16060101
[Journal Article] An essential role of the universal polarity protein, aPKCλ, on the maintenance of podocyte slit diaphragms.2009
- Author(s)
  Hirose T, Satoh D, Kurihara H, Kusaka C, Hirose H, Akimoto K, Matsusaka T, Ichikawa I, Noda T, Ohno S.
- Journal Title
  
  PLoS One. 4(1)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16060101
[Journal Article] Interaction between PAR-3 and the aPKC-PAR-6 complex is indispensable for apical domain development of epithelial cells.2009
- Author(s)
  Horikoshi Y, Suzuki A, Yamanaka T, Sasaki K, Mizuno K, Sawada H, Yonmura S, Ohno S
- Journal Title
  
  Journal of Cell Science 122(10)
  
  Pages: 1595-1606
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] An essential role of the universal polarity protein, aPKClambda, on the maintenance of podocyte slit diaphragms2009
- Author(s)
  Hirose, T.
- Journal Title
  
  PLoS ON 4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16060101
[Journal Article] An essential role of the aPKC-Aurora A-NDEL1 pathway in neurite elongationby modulation of microtubule dynamics.2009
- Author(s)
  Mori D, Yamada M, Mimori-Kiyosue Y, Shirai Y, Suzuki A, Ohno S, Saya H, Wynshaw-Boris A, Hirotsune S
- Journal Title
  
  Nat Cell Biol 11(9)
  
  Pages: 1057-1068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] A cell polarity protein aPKC1ambda is required for eye lens formation and growth.2009
- Author(s)
  Sugiyama Y, Akimoto K, Robinson M.L, Ohno S, Qinlan R.A
- Journal Title
  
  Dev Biol 336(2)
  
  Pages: 246-256
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] An essential role of the universal polarity protein, aPKClambda, on the maintenance of podocyte slit diaphragms.2009
- Author(s)
  Hirose T, Satoh D, Kurihara H, Kusaka C, Hirose H, Akimoto K, Matsusaka T, Ichikawa I, Noda T, Ohno S
- Journal Title
  
  PLoS ONE 4(1)
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] An essential role of the universal polarity protein, aPKC1ambda, on the maintenance of podocyte slit diaphragms.2009
- Author(s)
  Hirose T, Satoh D, Kurihara H, Kusaka C, Hirose H, Akimoto K, Matsusaka T, Ichikawa I, Noda T, Ohno S
- Journal Title
  
  PLoS ONE 4(1)
  
  Pages: 4194-4194
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] The 8th and 9th tandem spectrin-like repeats of utrophin cooperatively form a functional unit to interact with polarity-regulating kinase PAR-1b.2009
- Author(s)
  Yamashita K, Suzuki a, Satoh Y, Ide M, Amano Y, Masuda-Hirata M, Hayasi Y.K, Hamada K, Ogata K, Ohno S
- Journal Title
  
  Biochem Biophys Res.Commun 391(1)
  
  Pages: 812-817
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] Interaction between PAR-3 and the aPKC-PAR-6 complex is indispensable for apical domain development of epithelial cells2009
- Author(s)
  Horikoshi Y, Suzuki A, Yamanaka T, Sasaki K, Mizuno K, Sawada H, Yonemura S, Ohno S
- Journal Title
  
  Journal of Cell Science 122(10)
  
  Pages: 1595-1606
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated Mrna decay.2009
- Author(s)
  Yamashita A, Izumi N, Kashima I, Ohnishi T, Saari B, Katsuhata Y, Muramatsu R, Morita T, Iwamatsu A, Hachiya T, Kurata R, Hirano H, Anderson P, Ohno S
- Journal Title
  
  Genes & Development 23(9)
  
  Pages: 1091-1105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] Interaction between PAR-3 and the aPKC-PAR-6 complex is indispensable for apical domain development of epithelial cells.2009
- Author(s)
  Horikoshi Y, Suzuki A, Yamanaka T, Sasaki K, Mizuno K, Sawada H, Yonemura S, Ohno S
- Journal Title
  
  J. Cell Science 122(10)
  
  Pages: 1595-1606
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay2009
- Author(s)
  Yamashita A, Izumi N, Kashima I, Ohnishi T, Saari B, Katsuhata Y, Muramatsu R, Morita T, Iwamatsu A, Hachiya T, Kurata R, Hirano H, Anderson P, Ohno S
- Journal Title
  
  Genes & Development 23(9)
  
  Pages: 1091-1105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] An essential role of the universal polarity protein, aPKClambda, on the maintenance of podocyte slit diaphragms2009
- Author(s)
  Hirose T, Satoh D, KuriharaH, Kusaka C, Hirose H, Akimoto K, Matsusaka T, Ichikawa I, Noda T, Ohno S
- Journal Title
  
  PLoS ONE 4(1)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] High expression of atypical protein kinase C lambda/iota in gastric cancer as a prognostic factor for recurrence.2009
- Author(s)
  Takagawa R, Akimoto K, Ichikawa Y, Akiyama H, Kojima Y, Ishiguro H, Inayama Y, Aoki I, Kunisaki C, Endo I, Nagashima Y, Ohno S
- Journal Title
  
  Ann Surg Oncol 17(1)
  
  Pages: 81-88
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] A cell polarity protein aPKClambda is required for eye lens formation and growth.2009
- Author(s)
  Sugiyama Y, Akimoto K, Robinson M L, Ohno S, Quinlan R A
- Journal Title
  
  Dev Biol 336(2)
  
  Pages: 246-256
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] aPKClambda/iota promotes growth of prostate cancer cells in an autocrine manner through transcriptional activation of interleukin-6.2009
- Author(s)
  Ishiguro H, Akimoto K, Nagashima Y, Kojima Y, Sasaki T, Ishiguro-Imagawa Y, Nakaigawa N, Ohno S, Kubota Y, Uemura H
- Journal Title
  
  Proc Natl Acad Sci U S A 106(38)
  
  Pages: 16369-16374
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] Intracellular polarity protein PAR-1 regulates extracellular laminin assembly by regulating the dystroglycan complex.2009
- Author(s)
  Masuda-Hirata M, Suzuki A, Amano Y, Yamashita K, Ide M, Yamanaka T, Sakai M, Imamura M, Ohno S
- Journal Title
  
  Genes Cells 14(7)
  
  Pages: 835-850
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] An essential role of the aPKC-Aurora A-NDEL1 pathway in neurite elongation by modulation of microtubule dynamics.2009
- Author(s)
  Mori D, Yamada M, Mimori-Kiyosue Y, Shirai Y, Suzuki A, Ohno S, Saya H, Wynshaw-Boris A, Hirotsune S
- Journal Title
  
  Nat Cell Biol 11(9)
  
  Pages: 1057-1068
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay.2009
- Author(s)
  Yamashita A, Izumi N, Kashima I, Ohnishi T, Saari B, Katsuhata Y, Muramatsu R, Morita T, Iwamatsu A, Hachiya T, Kurata R, Hirano H, Anderson P, Ohno S
- Journal Title
  
  Genes Dev. 23(9)
  
  Pages: 1091-1105
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] High expression of atypical protein kinase C lambda/iota in gastric cancer as aprognostic factor for recurrence.2009
- Author(s)
  Takagawa R, Akimoto K, Ichikawa Y, Akiyama H, Kojima Y, Ishiguro H, Inayama Y, Aoki I, Kunisaki C, Endo I, Ngashima Y, Ohno S
- Journal Title
  
  Ann Surg Oncol 17(1)
  
  Pages: 81-88
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] The overexpression and altered localization of the atypical protein kinase C lambda/iota in breast cancer correlates with the pathologic type of these tumors2008
- Author(s)
  Kojima Y, Akimoto K, Nagashima Y, Ishiguro H, Shirai S, Chishima T, Ichikawa Y, Ichikawa T, Sasaki T, Kubota Y, InayamaY, Aoki I, Ohno S, Shimada H
- Journal Title
  
  Hum Pathol 39(6)
  
  Pages: 824-831
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] aPKC restricts the basolateral determinant PtdIns(3, 4, 5)P3 to the basal region.2008
- Author(s)
  Takahama S, Hirose T, Ohno S
- Journal Title
  
  Biochem Biophys Res Commun 368(2)
  
  Pages: 249-255
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] .aPKC restricts the basolateral determinant PtdIns(3,4,5)P3 to the basal region2008
- Author(s)
  Takahama S, Hirose T, Ohno S
- Journal Title
  
  Biochem.Biophys.Res.Commun 368(2)
  
  Pages: 249-255
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] Role of Lgl/Dlg/Scribble in the regulation of epithelial junction, polarity and growth.2008
- Author(s)
  Yamanaka T, Ohno S
- Journal Title
  
  Front Biosci 13
  
  Pages: 6693-6707
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] aPKC enables development of zonula adherens by antagonizing centripetal contraction of the circumferential actomyosin cables.2008
- Author(s)
  Kishikawa M, Suzuki A, Ohno S
- Journal Title
  
  J Cell Sci 121(Pt15)
  
  Pages: 2481-2492
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] Rho-kinase phosphorylates PAR-3 and disrupts PAR complex formation2008
- Author(s)
  Nakayma M, Goto TM, Sugimoto M, Nishimura T, Shinagawa T, Ohno S, Amano M, Kaibuchi K
- Journal Title
  
  Dev.Cell 14(2)
  
  Pages: 205-215
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] Rho-kinase phosphorylates PAR-3 and disrupts PAR complex formation.2008
- Author(s)
  Nakayama M, Goto T. M, Sugimoto M, Nishimura T, Shinagawa T, Ohno S, Amano M, Kaibuchi K
- Journal Title
  
  Dev Cell 14(2)
  
  Pages: 205-215
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] aPKC enables development of zonula adherens by antagonizing centripeta 1 contraction of the circumferential actomyosin cables2008
- Author(s)
  Kishikawa M, Suzuki A, Ohno S
- Journal Title
  
  Journal of Cell Science 121(Pt15)
  
  Pages: 2481-2492
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] aPKC restricts the basolateral determinant PtdIns(3,4,5)P3 to the basal region2008
- Author(s)
  Takahama S, Hirose T, Ohno S
- Journal Title
  
  Biochem. Biophys. Res. Commun 368(2)
  
  Pages: 249-255
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] The over- expression and altered localization of the atypical protein kinase C lambda/iota in breast cancer correlates with the pathologic type of these tumors.2008
- Author(s)
  Kojima Y, Akimoto K, Nagashima Y, Ishiguro H, Shirai S, Chishima T, Ichikawa Y, Ishikawa T, Sasaki T, Kubota Y, Inayama Y, Aoki I, Ohno S, Shimada H
- Journal Title
  
  Hum Pathol 39(6)
  
  Pages: 824-831
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] Helicobacter pylori CagA targets PARI/MARK kinase disrupt epitheila1 ecll polarity2007
- Author(s)
  Saadat I, Higashi H, Obuse C, Umeda M, Murata-Kamiya N, Saito Y, Lu H, Ohnishi N, Axuma T, Suzuki A, Ohno S, Hatakeyama M
- Journal Title
  
  Nature 447(7142)
  
  Pages: 330-333
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] Extrinsic Wnt signalling controls the polarity component aPKC.2007
- Author(s)
  Ohno S
- Journal Title
  
  Nat. Cell Biol. 9(7)
  
  Pages: 738-740
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] Distant N-and C-terminal domains are required for intrinsic kinase activity of SMG-1, a critical component of nonsense-mediated mRNA decay.2007
- Author(s)
  Morita T, Yamashita A, Kashima I, Ogata K, Ishiura S, Ohno S
- Journal Title
  
  J. Biol., Chem. 282(11)
  
  Pages: 7799-7808
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17209010
[Journal Article] Distant N-and C-terminaldomains are required for intrins kinase activi ty Of SMG-1, a critical component of nonsense-mediated mRNA decay2007
- Author(s)
  Morita T, Yamashit A, Kashima I, Ogata K, Ishiura S, Ohno S
- Journal Title
  
  J.Biol, Chem 282(11)
  
  Pages: 7799-7808
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] Distant N- and C-terminal domains are required for intrinsic kinase activity of SMG-1,a critical component of nonsense-mediated mRNA decay.2007
- Author(s)
  Morita T, Yamashita A, Kashima I, 0gata K, Ishiura S, Ohno S
- Journal Title
  
  J.Biol.,Chem. 282(11),
  
  Pages: 7799-7808
- Data Source
  KAKENHI-PROJECT-17209010
[Journal Article] Distant N-and C-terminal domains are required for intrinsic kinase activity of SMG-1, a critical component of nonsense-mediated mRNA decay.2007
- Author(s)
  Morita T, Yamashita A, Kashima I, Ogata K, Ishiura S, Ohno S
- Journal Title
  
  J.Biol., Chem. 282(11)
  
  Pages: 7799-7808
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209010
[Journal Article] Neonatal pancreatic cells redifferentiate into both neural and pancreatic li neages2007
- Author(s)
  Zhao W, Hirose T, Ishikawa M, Oshima Y, Hirai S, Ohno S, Taniguchi H
- Journal Title
  
  Bioche, Biophys.Res.Commun 352(1)
  
  Pages: 84-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] Polarity-regulating kinase partitioning- defective 1/microtubule affinity-regulating kinase 2 negatively regulates development of dendrites on hippocampal neurons.2007
- Author(s)
  Terabayashi T, Itoh T. J, Yamaguchi H, Yoshimura Y, Funato Y, Ohno S, Miki H
- Journal Title
  
  J Neurosci 27(48)
  
  Pages: 13098-107
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] Helicobacter pylori CagA targets PAR1/MARK kinase to disrupt epithelial cell polarity.2007
- Author(s)
  Saadat I, Higashi H, Obuse C, Umeda M, Murata-Kamiya N, Saito Y, Lu H, Ohnishi N, Azuma T, Suzuki A, Ohno S, Hatakeyama M
- Journal Title
  
  Nature 447(7142)
  
  Pages: 330-333
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] Extrinsic Wnt singalling controls the polarity component aPKC2007
- Author(s)
  Ohno S
- Journal Title
  
  Nat.Cell Biol. 9(7)
  
  Pages: 738-740
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] Loss of Partitiong-defective-3/Isotye-Specific Interacting Protein(Par-3/ASIP)in the Elongating Spermatid of RA175(IGSF4A/SynCAM)Deficieen Mice2007
- Author(s)
  Fujita E, Tanabe Y, Hirose T, Suzuki A, Aurrand-Lions M, Kasahara T, Imhof B.A, Ohno S, Momoi T
- Journal Title
  
  AmericanJ.Pathology 171(6)
  
  Pages: 1800-1810
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] Neonatal pancreatic cells redifferentiate into both neural and pancreatic lineages. Biochem.2007
- Author(s)
  Zhao W, Hirose T, Ishikawa M, Oshima Y, Hirai S, Ohno S, Taniguchi H
- Journal Title
  
  Biophys. Res. Commun. 352(1)
  
  Pages: 84-90
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] Polarity-regulating kinase Parlb/MARK2 negatively regulates development of dendrites on hippocampal neurons2007
- Author(s)
  Terabayshi T, Itoh T.J, Yamaguchi H, Yoshimura Y, Funato Y, Ohno S, Miki H
- Journal Title
  
  J.Neuroscience 27(48)
  
  Pages: 13098-13107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] Distant N- and C-terminal domains are required for intrinsic kinase activity of SMG-1, a critical component of nonsense-mediated mRNA decay.2007
- Author(s)
  Morita T, Yamashita A, Kashima I, Ogata K, Ishiura S, Ohno S
- Journal Title
  
  J. Biol. Chem. 282(11)
  
  Pages: 7799-7808
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] Loss of partitioning-defective-3/isotype -specific interacting protein (par-3/ASIP) in the elongating spermatid of RA175 (IGSF4A/SynCAM)-deficient mice.2007
- Author(s)
  Fujita E, Tanabe Y, Hirose T, Aurrand-Lions M, Kasahara T, Imhof B. A, Ohno S, Momoi T
- Journal Title
  
  Am J Pathol 171(6)
  
  Pages: 1800-10
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] mRNA品質管理システムにおけるナンセンスコドン認識の分子機構2006
- Author(s)
  鹿島勲, 山下暁朗, 大野茂男
- Journal Title
  
  実験医学 24(7)
  
  Pages: 963-966
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17209010
[Journal Article] JNK activator DLK regulates axon growth and neuronal migration in the developing cerebral cortex.2006
- Author(s)
  Hirai S-I, Cui1 DF, Miyata T, Ogawa M, Kiyonari H, Suda Y, Aizawa S, Banba Y, Ohno S
- Journal Title
  
  J. Neuroscience 15,26(46)
  
  Pages: 11992-12002
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] Lgl mediates apical domain disassembly by suppressing PAR-3/aPKC/PAR-6 complex to orient apical membrane polarity.2006
- Author(s)
  Yamanaka T, Horikoshi Y, Izumi N, Suzuki A, Mizuno K, Ohno S
- Journal Title
  
  J. Cell Science 119
  
  Pages: 2107-2118
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] Lgl mediates apical domain disassembly by suppressing PAR-3/aPKC/PAR-6 complex to orient apical membrane polarity.2006
- Author(s)
  Yamanaka T, Horikoshi Y, Izumi N, Suzuki A, Mizuno K, Ohno S
- Journal Title
  
  J.Cell Science 119
  
  Pages: 2107-2118
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] An association between the initial SMG-1-Upfl-eRF1-eRF3 complex and exon junction complex on mRNP is required for the SMG-1-mediated phosphorylation of Upf1 during nonsense-mediated mRNA decay.2006
- Author(s)
  Kashima I, Yamashita A, Izumi N, Kataoka N, Morishita R, Hoshino S, Ohno M, Dreyfuss G, Ohno S
- Journal Title
  
  Genes Dev. 20(3)
  
  Pages: 355-367
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] Specific inhibition of nonsense-mediated mRNA decay components,SMG-1 or Upf1, rescues the phenotype of Ullrich's disease fibroblasts.2006
- Author(s)
  Usuki F, Yamashita A, Kashima I, Higuchi I, Mitsuhiro Osame M, Ohno S
- Journal Title
  
  Molecular Therapy 14,3
  
  Pages: 351-360
- Data Source
  KAKENHI-PROJECT-17209010
[Journal Article] Binding of a novel SMG-1-Upfl-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upflphosphorylation and nonsense-mediated mRNA decay.2006
- Author(s)
  Kashima I, Yamashita A, Izumi N, Kataoka N, Morishita R, Hoshino S, Ohno M, Dreyfuss G, Ohno S
- Journal Title
  
  Genes Dev. 20(3)
  
  Pages: 355-367
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209010
[Journal Article] Inactivation of aPKC λ results in a loss of adherens junctions in neuroepithelial cells without affecting neurogenesis in mouse neocortex.2006
- Author(s)
  Imai F, Hirai S-I, Akimoto K, Koyama H, Miyata T, Ogawa M, Noguchi S, Sasaoka T, Noda T, Ohno S
- Journal Title
  
  Development 133(9)
  
  Pages: 1735-1744
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] The role of SMG-1-Mediated phosphorylation of UPF1 in NMD.2006
- Author(s)
  Yamashita A, Kashima I, Ohno S
- Journal Title
  
  In Nonsense-Mediated mRNA Decay, Maquat, Landes Bioscience (ISBN No. 1-58706-296-8)
  
  Pages: 85-95
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209010
[Journal Article] The PAR-aPKC system : lessons in polarity.2006
- Author(s)
  Suzuki A, Ohno S
- Journal Title
  
  J.Cell Science 119
  
  Pages: 979-987
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1phosphorylation and nonsense-mediated mRNA decay.2006
- Author(s)
  Kashima I, Yamashita A, Izumi N, Kataoka N, Morishita R, Hoshino S, Ohno M, Dreyfuss G, Ohno S
- Journal Title
  
  Genes Dev. 20(3)
  
  Pages: 355-367
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17209010
[Journal Article] Inactivation of aPKCλresults in a loss of adherens junctions in neuroepithelial cells without affecting neurogenesis in mouse neocortex.2006
- Author(s)
  Imai F, Hirai S-I, Akimoto K, Koyama H, Miyata T, Ogawa M, Noguchi S, Sasaoka T, Noda T, Ohno S
- Journal Title
  
  Development 133(9)
  
  Pages: 1735-1744
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] The PAR-aPKC system: lessons in polarity.2006
- Author(s)
  Suzuki A, Ohno S
- Journal Title
  
  J Cell Sci 119
  
  Pages: 979-987
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] A distinct PAR complex associates physically with VE-cadherin in vertebrate endothelial cells.2006
- Author(s)
  Iden S, Rehder D, August B, Suzuki A, Wolburg-Buchholz K, Woburg H, Ohno S, Behrens J, Vestweber D, Klaus E
- Journal Title
  
  EMBO Rep. 7(12)
  
  Pages: 1239-1246
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] An association between the initial SMG-1-Upf1-eRF1-eRF3 complex and exon junction complex on mRNP is required for the SMG-1-mediated phosphorylation of Upf1 during nonsense-mediated mRNA decay.2006
- Author(s)
  Kashima I, Yamashita A, lzumi N, Kataoka N, Morishita R, Hoshino S, Ohno M, Dreyfuss G, Ohno S
- Journal Title
  
  Genes Dev. 20(3)
  
  Pages: 355-367
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] Specific inhibition of nonsense-mediated mRNA decay components, SMG-1 or Upf1, rescues the phenotype of Ullrich's disease fibroblasts.2006
- Author(s)
  Usuki F, Yamashita A, Kashima I, Higuchi I, Mitsuhiro, Osame M, Ohno S
- Journal Title
  
  Molecular Therapy 14(3)
  
  Pages: 351-360
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17209010
[Journal Article] PAR3 is essential for cyst-mediated epicardial development by establishing apical cortical domains.2006
- Author(s)
  Hirose T, Karasawa M, Sugitani Y, Fujisawa M, Akimoto K, Ohno S, Noda T
- Journal Title
  
  Development 133(7)
  
  Pages: 1389-1398
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upflphosphorylation and nonsense-mediated mRNA decay.2006
- Author(s)
  Kashima I, Yamashita A, Izumi N, Kataoka N, Morishita R, Hoshino S, Ohno M, Dreyfuss G, Ohno S
- Journal Title
  
  Genes Dev. 20(3)
  
  Pages: 355-367
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] Binding of a novel SMG-1-Upf1 -eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphory- lation and nonsense-mediated mRNA decay.2006
- Author(s)
  Kashima I, Yamashita A, Izumi N, Kataoka N, Morishita R, Hoshino S, Ohno M, Dreyfuss G, Ohno S
- Journal Title
  
  Genes Dev. 20(3)
  
  Pages: 355-367
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] Specific inhibition of nonsense-mediated mRNA decay components, SMG-1 or Upfl, rescues the phenotype of Ulrich' s disease fibroblasts.2006
- Author(s)
  Usuki F, Yamashita A, Kashima I, Higuchi I, Mitsuhiro Osame M, Ohno S
- Journal Title
  
  Molecular Therapy 14, 3
  
  Pages: 351-360
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209010
[Journal Article] The role of SMG-1-mediated phosphorylation of UPF1 in NMD.2006
- Author(s)
  Yamashita A, Kashima I, Ohno S
- Journal Title
  
  In Nonsense-Mediated mRNA decay
  
  Pages: 85-95
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17209010
[Journal Article] The {gamma}-Parvin-Integrin-Linked Kinase complex is critically involved in leukocyte-substrate interaction.2006
- Author(s)
  Yoshimi R, Yamaji S, Suzuki A, Mishima W, Okamura M, Obana T, Matsuda C, Miwa Y, Ohno S, Ishigatsubo Y
- Journal Title
  
  J.Immunology 176(6)
  
  Pages: 13611-13624
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] An association between the initial SMG-1-Upf1-eRF1-eRF3 complex and exon junction complex on mRNP is required for the SMG-1-mediated phosphorylation of Upf1 during nonsense-mediated mRNA decay.2006
- Author(s)
  Kashima I, Yamashita A, Izumi N, Kataoka N, Morishita R, Hoshino S, Ohno M, Dreyfuss G, Ohno S
- Journal Title
  
  Genes Dev. 20(3)
  
  Pages: 355-367
- Data Source
  KAKENHI-PROJECT-17209010
[Journal Article] PAR-6-PAR-3 mediates Cdc42-induced Rac activation through the Rac GEFs STEF/Tiam1.2005
- Author(s)
  Nishimura T, Yamaguchi T, Kato K, Yoshizawa M, Nabeshima Y, Ohno S, Hoshino M, Kaibuchi K
- Journal Title
  
  Nat.Cell Biol. 7(3)
  
  Pages: 270-277
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] The role of SMG-1 on nonsense-mediated mRNA decay.2005
- Author(s)
  Yamashita A, Kashima I, Ohno S
- Journal Title
  
  Biochem Biophys. Acta (Proteins and Proteomics), Inhibitors of Protein Kinases 1754(1-2)
  
  Pages: 305-315
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17209010
[Journal Article] Behavior of tight junction, adherens-junction and cell polarity proteins during HNF-4alpha-induced epithelial polarization.2005
- Author(s)
  Satohisa S, Chiba H, Osanai M, Ohno S, Kojima T, Saito T, Sawada N
- Journal Title
  
  Exp.Cell Res. 310(1)
  
  Pages: 66-78
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] PAR-6-PAR-3 mediates Cdc42-induced Rac activation through the Rac GEFs STEF/Tiam1.2005
- Author(s)
  Nishimura T, Yamaguchi T, Kato K, Yoshizawa M, Nabeshima Y, Ohno S, Hoshino M, Kaibuchi K
- Journal Title
  
  Nat. Cell Biol. 7(3)
  
  Pages: 270-277
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] Expression of MUK/DLK/ZPK, an activator of the JNK pathway, in the nervous systems of the developing mouse embryo.2005
- Author(s)
  Hirai S-I, Kawaguchi A, Suenaga J, Ono M, Cui de F, Ohno S
- Journal Title
  
  Gene Expr.Patterns 5(4)
  
  Pages: 517-523
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] The role of SMG-1 on nonsense-mediated mRNA decay. Biochem Biophys. Acta (Proteins and Proteomics)2005
- Author(s)
  Yamashita A, Kashima I, Ohno S
- Journal Title
  
  Inhibitors of Protein Kinases 1754(1-2)
  
  Pages: 305-315
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209010
[Journal Article] Function of aPKClambda in differentiating photoreceptors is required for proper lamination of mouse retina.2005
- Author(s)
  Koike C, Nishida A, Akimoto K, Nakaya M-A, Noda T, Ohno S, Furukawa T
- Journal Title
  
  J.Neurosci. 25(44)
  
  Pages: 10290-10298
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] The role of SMG-1 on nonsense-mediated mRNA decay.2005
- Author(s)
  Yamashita A, Kashima I, Ohno S
- Journal Title
  
  Biochem Biophys.Acta (Proteins and Proteomics), Inhibitors of Protein Kinases 1754(1-2)
  
  Pages: 305-315
- Data Source
  KAKENHI-PROJECT-17209010
[Journal Article] Asymmetric distribution of PAR proteins in the mouse embryo begins at the 8-cell stage during compaction.2005
- Author(s)
  Vinot S, Le T, Ohno S, Pawson T, Maro B, Louvet-Vallee S
- Journal Title
  
  Dev.Biol. 282(2)
  
  Pages: 307-319
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] Behavior of tight-junction, adherens-junction and cell polarity proteins during HNF-4alpha-induced epithelial polarization.2005
- Author(s)
  Satohisa S, Chiba H, Osanai M, Ohno S, Kojima T, Saito T, Sawada N
- Journal Title
  
  Exp.Cell Res. 310(1)
  
  Pages: 66-78
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] Role of SMG-1-Mediated phosphorylation of Upf1 in NMD. in Nonsense-Mediated mRNA decay.2005
- Author(s)
  Yamashita A, Kashima I, Ohno S
- Journal Title
  
  Maquat, Landes Bioscience, (ISBN No.1-58706-296-8) -
  
  Pages: 85-95
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] The role of SMG-1 on nonsense-mediated mRNA decay.2005
- Author(s)
  Yamashita A, Kashima I, Ohno S
- Journal Title
  
  Biochem Biophys.Acta (Proteins and Proteomics), Inhibitors of Protein Kinases 1754(1-2)
  
  Pages: 305-315
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] Role of SMG-1-Mediated Phosphorylation of Upf1 in NMD. In Nonsense-Mediated mRNA Decay,2005
- Author(s)
  Yamashita A, Kashima I, Ohno S
- Journal Title
  
  Maquat, Landes Bioscience, (ISBN No.1-58706-296-8)
  
  Pages: 85-95
- Data Source
  KAKENHI-PROJECT-17209010
[Journal Article] The first CH domain of affixin activates Cdc42 and Rac1 through a1 phaPIX, a Cdc42/Rac1-specific guanine nucleotide exchanging factor.2004
- Author(s)
  Mishima W, Suzuki A, Yamaji S, Yoshimi R, Ueda A, Kaneko T, Tanaka J, Miwa Y, Ohno S, Ishigatsubo Y
- Journal Title
  
  Genes Cells 9(3)
  
  Pages: 193-204
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209013
[Journal Article] Affixin interacts with α-actin and mediates integrin signaling for reorganization of F-actin induced by initial cell-substrate interaction2004
- Author(s)
  Yamaji, S., Suzuki, A., Kanamori, H., Mishima, W., Yoshimi, R., Takasaki, H., Takabayashi, M., Fujimaki, K., Fujisawa, S., Ohno, S., Ishigatsubo, Y.
- Journal Title
  
  J. Cell Biology 165(4)
  
  Pages: 539-551
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209013
[Journal Article] hUPF1のリン酸化と脱リン酸化によるmRNA監視複合体リモデリング2004
- Author(s)
  山下暁朗, 鹿島勲, 大野茂男
- Journal Title
  
  実験医学 22(4)
  
  Pages: 522-525
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209013
[Journal Article] Role of the PAR-3-KIF3 complex in the establishment of neuronal polarity2004
- Author(s)
  Nishimura, T., Kato, K., Yamaguchi, T., Fukata, Y., Ohno, S., Kaibuchi, K.
- Journal Title
  
  Nat. Cell Biol. 6(4)
  
  Pages: 328-334
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209013
[Journal Article] aPKC acts upstream of PAR-1b in both the establishment and maintenance of mammalian epithelial polarity.2004
- Author(s)
  Suzuki A, Hirata M, Amano Y, Izumi N, Miwa Y, Ohno S
- Journal Title
  
  Curr Biolology 14(16)
  
  Pages: 1425-1435
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12219215
[Journal Article] The first CH domain of affixin activates Cdc42 and Rac1 through alphaPIX, a Cdc42/Rac1-specific guanine nucleotide exchanging factor.2004
- Author(s)
  Mishima W, Suzuki A, Yamaji S, Yoshimi R, Ueda A, Kaneko T, Tanaka J, Miwa Y, Ohno S
- Journal Title
  
  Genes Cells 9(3)
  
  Pages: 193-204
- Data Source
  KAKENHI-PROJECT-15209013
[Journal Article] Inhibition of nonsense-mediated mRNA decay rescues the phenotype in Ullrich's disease.2004
- Author(s)
  Usuki F, Yamashita A, Higuchi I, Ohnishi T, Shiraishi T, Osame M, Ohno S.
- Journal Title
  
  Ann Neurol. 55(5)
  
  Pages: 740-744
- Data Source
  KAKENHI-PROJECT-12219215
[Journal Article] Inhibition of nonsense-mediated mRNA decay rescues the phenotype in Ullrich's disease.2004
- Author(s)
  Usuki F, Yamashita A, Higuchi I, Ohnishi T, Shiraishi T, Osame M, Ohno S.
- Journal Title
  
  Ann Neurol. 55(5)
  
  Pages: 740-744
- Data Source
  KAKENHI-PROJECT-15209013
[Journal Article] Affixin interacts with alpha-actinin and mediates integrin signaling for reorganization of F-actin induced by initiat cell-substrate interaction.2004
- Author(s)
  Fujisawa S, Ohno S, Ishigatsubo Y.
- Journal Title
  
  J Cell Biol 165(4)
  
  Pages: 539-551
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12219215
[Journal Article] Junctional adhesion molecules (JAMs) : more molecules with dual functions?2004
- Author(s)
  Ebnet K, Suzuki A, Ohno S, Vestweber D
- Journal Title
  
  J Cell Sci 117(Pt 1)
  
  Pages: 19-29
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12219215
[Journal Article] The first CH domain of affixin activates Cdc42 and Rac1 through alphaPIX, a Cdc42/Rac1-specific guanine nucleotide exchanging factor2004
- Author(s)
  Mishima, W., Suzuki, A., Yamaji, S., Yoshimi, R., Ueda, A., Kaneko, T., Tanaka, J., Miwa, Y., Ohno, S., Ishigatsubo, Y.
- Journal Title
  
  Genes Cells 9(3)
  
  Pages: 193-204
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209013
[Journal Article] Affixin interacts with alpha-actinin and mediates integrin signaling for reorganization of F-actin induced by initial cell-substrate interaction.2004
- Author(s)
  Fujisawa S, Ohno S, Ishigatsubo Y.
- Journal Title
  
  J Cell Biol. 165(4)
  
  Pages: 539-551
- Data Source
  KAKENHI-PROJECT-12219215
[Journal Article] Junctional adhesion molecules (JAMs) : more molecules with dual functions?2004
- Author(s)
  Ebnet K, Suzuki A, Ohno S, Vestweber D
- Journal Title
  
  J Cell Sci. 117(Pt1)
  
  Pages: 19-29
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12219215
[Journal Article] Affixin interacts with alpha-actinin and mediates integrin signaling for reorganization of F-actin induced by initial cell-substrate interaction.2004
- Author(s)
  Yamaji S, Suzuki A, Kanamori H, Mishima W, Yoshimi R, Takasaki H, Takabayashi M, Fujimaki K, Fujisawa S, Ohno S, Ishigatsubo Y
- Journal Title
  
  J.Cell Biol. 165(4)
  
  Pages: 539-551
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209013
[Journal Article] aPKC acts upstream of PAR-1b in both the establishment and maintenance of mammalian epithelial polarity.2004
- Author(s)
  Suzuki A, Hirata M, Kamimura K, Maniwa R, Yamanaka T, Mizuno K, Kishikawa M, Hirose H, Amano Y, Izumi N, Miwa Y, Ohno S.
- Journal Title
  
  Curr Biology 14(16)
  
  Pages: 1425-1435
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12219215
[Journal Article] Affixin interacts with alpha-actinin and mediates integrin signaling for reorganization of F-actin induced by initial cell-substrate interaction.2004
- Author(s)
  Fujisawa S, Ohno S, Ishigatsubo Y.
- Journal Title
  
  J Cell Biol. 165(4)
  
  Pages: 539-551
- Data Source
  KAKENHI-PROJECT-15209013
[Journal Article] Affixin interacts with alpha-actinin and mediates integrin signaling for reorganization of F-actin induced by initial cell-substrate interaction.2004
- Author(s)
  Fujisawa S, Ohno S, Ishigatsubo Y
- Journal Title
  
  J Cell Biol. 165(4)
  
  Pages: 539-551
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12219215
[Journal Article] Junctional adhesion molecules (JAMs) : more molecules with dual functions?2004
- Author(s)
  Ebnet K, Suzuki A, Ohno S, Vestweber D.
- Journal Title
  
  J Cell Sci. 117(Pt1)
  
  Pages: 19-29
- Data Source
  KAKENHI-PROJECT-12219215
[Journal Article] functional adhesion molecules (JAMs) : more molecules with dual functions?2004
- Author(s)
  Ebnet K, Suzuki A, Ohno S, Vestweber D
- Journal Title
  
  J.Cell Sci. 117(Pt1)
  
  Pages: 19-29
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209013
[Journal Article] Inhibition of nonsense-mediated mRNA decay rescues the phenotype in Ullrich's disease2004
- Author(s)
  Usuki, F., Yamashita, A., Higuchi, I., Ohnishi, T., Shiraishi, T., Osame, M., Ohno, S.
- Journal Title
  
  Annals of Neurology 55
  
  Pages: 740-744
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209013
[Journal Article] The first CH domain of affixin activates Cdc42 and Rac1 through alphaPIX, a Cdc42/Rac1-specific guanine nucleotide exchanging factor.2004
- Author(s)
  Mishima W, Suzuki A, Yamaji S, Yoshimi R, Ueda A, Kaneko T, Tanaka J, Miwa Y, Ohno S
- Journal Title
  
  Genes Cells 9(3)
  
  Pages: 193-204
- Data Source
  KAKENHI-PROJECT-12219215
[Journal Article] Junctional adhesion molecules (JAMs): more molecules with dual functions?2004
- Author(s)
  Ebnet, K., Suzuki, A., Ohno, S., Vestweber, D.
- Journal Title
  
  J. Cell Sci. 117(Pt 1)
  
  Pages: 19-29
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209013
[Journal Article] Role of the PAR-3-KIF3 complex in the establishment of neuronal polarity.2004
- Author(s)
  Nishimura T, Kato K, Yamaguchi T, Fukata Y, Ohno S, Kaibuchi K.
- Journal Title
  
  Nat Cell Biol. 6(4)
  
  Pages: 328-334
- Data Source
  KAKENHI-PROJECT-15209013
[Journal Article] Junctional adhesion molecules (JAMs) : more molecules with dual functions?2004
- Author(s)
  Ebnet K, Suzuki A, Ohno S, Vestweber D.
- Journal Title
  
  J Cell Sci. 117(Pt1)
  
  Pages: 19-29
- Data Source
  KAKENHI-PROJECT-15209013
[Journal Article] Role of the PAR-3-KIF3 complex in the establishment of neuronal polarity.2004
- Author(s)
  Nishimura T, Kato K, Yamaguchi T, Fukata Y, Ohno S, Kaibuchi K
- Journal Title
  
  Nat Cell Biol. 6(4)
  
  Pages: 328-334
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12219215
[Journal Article] Inhibition of nonsense-mediated mRNA decay rescues the phenotype in Ullrich's disease.2004
- Author(s)
  Usuki F, Yamashita A, Higuchi I, Ohnishi T, Shiraishi T, Osame M, Ohno S
- Journal Title
  
  Ann.Neurol. 55(5)
  
  Pages: 740-744
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209013
[Journal Article] Role of the PAR-3-KIF3 complex in the establishment of neuronal polarity.2004
- Author(s)
  Nishimura T, Kato K, Yamaguchi T, Fukata Y, Ohno S, Kaibuchi K
- Journal Title
  
  Nat.Cell Biol. 6(4)
  
  Pages: 328-334
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209013
[Journal Article] Role of the PAR-3-KIF3 complex in the establishment of neuronal polarity.2004
- Author(s)
  Nishimura T, Kato K, Yamaguchi T, Fukata Y, Ohno S, Kaibuchi K.
- Journal Title
  
  Nat Cell Biol. 6(4)
  
  Pages: 328-334
- Data Source
  KAKENHI-PROJECT-12219215
[Journal Article] Role of the PAR-3-KIF3 complex in the establishment of neuronal polarity..2004
- Author(s)
  Nishimura T, Kato K, Yamaguchi T, Fukata Y, Ohno S, Kaibuchi K.
- Journal Title
  
  Nat Cell Biol 6(4)
  
  Pages: 328-334
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12219215
[Journal Article] Phosphorylation of hUPF1 Induces Formation of mRNA Surveillance Complexes Containing hSMG-5 and hSMG-7.2003
- Author(s)
  Ohnishi, T., Yamashita, A, Matthias W., Hentze, M.W., Anderson, P., Ohno, S
- Journal Title
  
  Molecular Cell 12(5)
  
  Pages: 1187-1200
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12219215
[Journal Article] Mammalian Lg1 forms a protein complex with PAR-6 and aPKC independently of PAR-3 to regulate epithelial cell polarity2003
- Author(s)
  Yamanaka, T., Horikoshi, Y., Sugiyama, Y., Ishiyama, C., Suzuki, A., Hirose, T., Iwamatsu, A., Shinohara, A., Ohno, S.
- Journal Title
  
  Current Biology 13
  
  Pages: 734-743
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209013
[Journal Article] Mammalian Lg1 forms a protein complex with PAR-6 and aPKC independently of PAR-3 to regulate epithelial cell polarity.2003
- Author(s)
  Yamanaka, T., Horikoshi, Y., Sugiyama, Y., Ishiyama, C., Suzuki, A., Hirose, T., Iwamatsut, A., Shinohara, A., Ohno, S.
- Journal Title
  
  Current Biology 13
  
  Pages: 734-743
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12219215
[Journal Article] Self-association of PAR-3 mediated by the conserved N-terminal domain contributes to the development of epithelial tight junctions.2003
- Author(s)
  Mizuno, K., Suzuki, A., Hirose, T., Kitamura, K., Kutsuzawa, Y., Futaki, M., Amano, Y., Ohno, S.
- Journal Title
  
  J. Biol. Chem. 278(33)
  
  Pages: 31240-31250
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12219215
[Journal Article] Self-association of PAR-3 mediated by the conserved N-terminal domain contributes to the development of epithelial tight junctions.2003
- Author(s)
  Mizuno K, Suzuki A, Hirose T, Kitamura K, Kutsuzawa K, Futaki M, Amano Y, Ohnos S
- Journal Title
  
  J.Biol.Chem 278(33)
  
  Pages: 31240-31250
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209013
[Journal Article] Protein Kinase Cl/i (PKCl/i): A PKC isotype essential for the development of multicellular organisms2003
- Author(s)
  Suzuki, A., Akimoto, K., Ohno, S.
- Journal Title
  
  J. Biochemistry 133
  
  Pages: 9-16
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209013
[Journal Article] Protein kinase C 1/I (PKC 1/I): aPKC isotype essential for the development of multicellular organism.2003
- Author(s)
  Suzuki A, Akimoto K, Ohno S
- Journal Title
  
  J.Biochem (Tokyo) 133(1)
  
  Pages: 9-16
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209013
[Journal Article] Self-association of PAR-3 mediated by the conserved N-terminal domain contributes to the development of epithelial tight junctions2003
- Author(s)
  Mizuno, K., Suzuki, A., Hirose, T., Kitamura, K., Kutsuzawa, K., Futaki, M., Amano, Y., Ohno, S.
- Journal Title
  
  J. Biol. Chem. 278(33)
  
  Pages: 31240-31250
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209013
[Journal Article] Phosphorylation of hUPF1 Induces Formation of mRNA Surveillance Complexes Containing hSMG-5 and hSMG-7.2003
- Author(s)
  Ohnishi, T., Yamashita, A., Kashima, I., Schell, T., Anders, K.R., Grimson, A., Hachiya, T., Matthias W.Hentze, M.W., Anderson, P., Ohno, S.
- Journal Title
  
  Molecular Cell 12(5)
  
  Pages: 1187-200
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12219215
[Journal Article] Loss of von Hippel-Lindau protein causes cell density-dependent deregulation of CyclinD1 expression through Hypoxia-inducible factor2003
- Author(s)
  Baba, M., Hirai, S-I., Yamada-Okabe, H., Hamada, K., Tabuchi, H., Kobayashi, K., Kondo, K., Yoshida, M., Yamashita, A., Kishida, T., Nakaigawa, N., Nagashima, Y., Kubota, Y., Yao, M., Ohno, S.
- Journal Title
  
  Oncogene 22
  
  Pages: 2728-2739
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209013
[Journal Article] The second phase activation of protein kinase C δ at late G1 is required for DNA synthesis in serum-induced cell cycle progression2003
- Author(s)
  Kitamura, K., Mizuno, K., Etoh, A., Akita, Y., Miyamoto, A., Nakayama, K-I., Ohno, S.
- Journal Title
  
  Genes to Cells 8
  
  Pages: 311-324
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209013
[Journal Article] Mammalian Lgl forms a protein complex with PAR-6 and aPKC independently of PAR-3 to regulate epithelial cell polarity.2003
- Author(s)
  Yamanaka T, Horikoshi Y, Sugiyama Y, Ishiyama C, Suzuki A, Hirose T, Iwamatsu A, Shinohara A, Ohno S
- Journal Title
  
  Current Biology 13(9)
  
  Pages: 734-743
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209013
[Journal Article] Self-association of PAR-3 mediated by the conserved N-terminal domain contributes to the development of epithelial tight junctions.2003
- Author(s)
  Mizuno, K., Suzuki, A., Hirose, T., Kitamura, K., Kutsuzawa, Y., Amano, Y., Ohno, S.
- Journal Title
  
  J. Biol. Chem. 278(33)
  
  Pages: 31240-31250
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12219215
[Journal Article] The second phase activation of protein kinase Cd at late G1 is required for DNA synthesis in serum-induced cell cycle progression.2003
- Author(s)
  Kitamura K, Mizuno K, Etoh A, Akita Y, Miyamoto A, Nakayama K-I, Ohno S
- Journal Title
  
  Genes to Cells 8
  
  Pages: 311-324
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209013
[Journal Article] Phosphorylation of hUPF1 Induces Formation of mRNA Surveillance Complexes Containing hSMG-5 and hSMG-72003
- Author(s)
  Ohnishi, T., Yamashita, A., Kashima, I., Schell, T., Anders, K.R., Grimson, A., Hachiya, T., Hentze, M.W., Anderson, P., Ohno, S.
- Journal Title
  
  Molecular Cell 12
  
  Pages: 1187-1200
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209013
[Journal Article] Phosphorylation of hUPF1 Induces Formation of mRNA Surveillance Complexes Containing hSMG-5 and hSMG-7.2003
- Author(s)
  Ohnishi T, Yamashita A, Kashima I, Schell T, Anders K R, Grimson A, Hachiya T, Hentze M W, Anderson P, Ohno S
- Journal Title
  
  Molecular Cell 12(5)
  
  Pages: 1187-1200
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209013
[Journal Article] Mammalian Lgl forms a protein complex with PAR-6 and aPKC independently of PAR-3 to regulate epithelial cell polarity.2003
- Author(s)
  Yamanaka, T., Horikoshi, Y., Shinohara, A, Ohno, S.
- Journal Title
  
  Current Biology 13(9)
  
  Pages: 734-743
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12219215
[Journal Article] Loss of von Hippel-Lindau protein causes cell density-dependent deregulation of CyclinD1 expression through Hypoxia-inducible factor.2003
- Author(s)
  Baba M, Hirai S-I, Yamada-Okabe H, Hamada K, Tabuchi H, Kobayashi K, Kondo K, Yoshida M, Yamashita A, Kishida T, Nakaigawa N, Nagashima Y, Kubota Y, Yao M, Ohno S
- Journal Title
  
  Oncogene 22(18)
  
  Pages: 2728-2738
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209013
[Journal Article] Increased proliferation of B cells and auto-immunity in mice lacking protein kinase Cdelta.2002
- Author(s)
  Miyamoto, A., Nakayama, K., Imaki, H., Ohno, S., Nakayama, K-I.
- Journal Title
  
  Nature 416
  
  Pages: 865-869
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12219215
[Journal Article] K-I. : Increased proliferation of B cells and auto-immunity in mice lacking protein kinase C delta.2002
- Author(s)
  Miyamoto, A., Nakayama, K., Imaki, H., Hirose, S., Jiang, Y., Abe, M., Tsukiyama, T., Nagahama, H., Ohno, S., Hatakeyama, S., Nakayama
- Journal Title
  
  Nature 416
  
  Pages: 865-869
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12219215
[Journal Article] aPKC kinase activity is required for the asymmetric differentiation of the premature junctional complex during epithelial cell polarizatioin.2002
- Author(s)
  Suzuki, A., Ishiyama, C., Hashiba, K., Shimizu, M., Ebnet, K., Takai, Y., Ohno, S
- Journal Title
  
  J.Cell Science 115
  
  Pages: 3565-3573
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12219215
[Journal Article] aPKC kinase activity is required for the asymmetric differentiation of the premature junctional complex during epithelial cell polarization.2002
- Author(s)
  Suzuki, A., Ishiyama, C., Hashiba, K., Shimizu, M., Ebnet, K., Takai, Y.Ohno, S.
- Journal Title
  
  J. Cell Science 115
  
  Pages: 3565-3573
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12219215
[Journal Article] Role of Lgl/Dlg/Scribble in the regulation of epithelial junction, polarity and growth
- Author(s)
  Yamanaka T, Ohno S
- Journal Title
  
  Frontiers in Bioscience (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] The overexpression and altered localization of the atypical Protein Kinase C lambda/iota in breast cancer correlates with the pathological type of these tumors
- Author(s)
  Kojima Y, Akimoto K, Nagashima Y, Ishiguro H, Shirai S, Chishima T, Ichikawa Y, Insiakama T, Sasaki T, Knbota Y, Knbota Y, Inayama Y, Aoki I, Ohno S, Shimada H
- Journal Title
  
  Human Pathology (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] Specific inhibition of nonsense-mediated mRNA decay components, SMG-1 or Upf1, rescues the phenotype of Ullrich's disease fibroblasts.
- Author(s)
  Usuki F, Yamashita A, Kashima I, Higuchi I, Mitsuhiro Osame M, Ohno S
- Journal Title
  
  Molecular Therapy (in press)
- Data Source
  KAKENHI-PROJECT-17209010
[Journal Article] ASPP2 Regulates Epithelial Cell Polarity through the PAR Complex.
- Author(s)
  Cong W, Hirose T, Harita Y, YamashitaA, Mizuno K, Hirano H, Ohno S.
- Journal Title
  
  Current Biology (in press)
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] Expression and localisation of apical junctional complex proteins in lens epithelial cells
- Author(s)
  Sugiyama Y, Prescott A.R, Tholozan^a F M D, Ohno S, Quinlan R A
- Journal Title
  
  Experimental Eye Research (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] Symmetrically dividing cell specific division axes alteration obsered in proteasome depleted C.elegans embryo
- Author(s)
  Sugiyama Y, Nishimura AOhno S
- Journal Title
  
  Mechanisms of Development (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] PAR-3 is essential for cyst-mediated epicardial development by establishing apical cortical domains.
- Author(s)
  Hirose, T.
- Journal Title
  
  Development in press
- Data Source
  KAKENHI-PROJECT-16060101
[Patent] 子宮頸がんの予防を目的とした前がん病変の増悪および軽快を予見する検査方法2014
- Inventor(s)
  大野茂男、水島大一、宮城悦子、佐藤美紀子、平原史樹、他
- Industrial Property Rights Holder
  大野茂男、水島大一、宮城悦子、佐藤美紀子、平原史樹、他
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-019201
- Filing Date
  2014-02-04
- Data Source
  KAKENHI-PLANNED-23112003
[Patent] 初期乳がんモデル用動物2009
- Inventor(s)
  秋本和憲、大野茂男
- Industrial Property Rights Holder
  公立大学法人横浜市立大学
- Filing Date
  2009-06-18
- Data Source
  KAKENHI-PROJECT-17014076
[Patent] 初期乳がんモデル用動物2007
- Inventor(s)
  秋本和憲、野田哲生、大野茂男
- Industrial Property Rights Holder
  横浜市立大学
- Industrial Property Number
  2007-167036
- Filing Date
  2007-06-25
- Data Source
  KAKENHI-PROJECT-17014076
[Patent] mRNAサーベイランス経路を制御するタンパク質2007
- Inventor(s)
  山下暁朗、大野茂男
- Industrial Property Rights Holder
  横浜市立大学
- Industrial Property Number
  2007-179140
- Filing Date
  2007-07-08
- Data Source
  KAKENHI-PROJECT-17014076
[Patent] SMG-1特異的siRNA及びmRNAサーベイランス機構抑制剤2003
- Inventor(s)
  大野茂男, 山下暁朗, 大西哲生
- Industrial Property Rights Holder
  科学技術振興事業団, 横浜市
- Industrial Property Number
  2003-191243
- Filing Date
  2003-07-03
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209013
[Patent] SMG-1特異的siRNA及びmRNAサーベイランス機構抑制剤2003
- Inventor(s)
  大野茂男, 山下暁朗, 大西哲生
- Industrial Property Rights Holder
  科学技術振興事業団, 横浜
- Industrial Property Number
  2003-191243
- Filing Date
  2003-07-03
- Data Source
  KAKENHI-PROJECT-12219215
[Patent] NMD阻害剤のスクリーニング方法2003
- Inventor(s)
  大野茂男, 鹿島勲
- Industrial Property Rights Holder
  セルフリーサイエンス
- Filing Date
  2003
- Data Source
  KAKENHI-PROJECT-12219215
[Patent] SMG-1特異的simRNA及びRNAサーベイランス機構抑制剤2003
- Inventor(s)
  大野茂男, 山下暁朗, 大西哲生
- Industrial Property Rights Holder
  科学技術振興事業団, 横浜
- Industrial Property Number
  2003-191243
- Filing Date
  2003-07-03
- Data Source
  KAKENHI-PROJECT-15209013
[Patent] NMD阻害剤のスクリーニング方法2003
- Inventor(s)
  大野茂男, 鹿島勲
- Industrial Property Rights Holder
  セルフリーサイエンス
- Filing Date
  2003
- Data Source
  KAKENHI-PROJECT-15209013
[Patent] NMD阻害剤のスクリーニング方法2003
- Inventor(s)
  大野茂男, 鹿島勲
- Industrial Property Rights Holder
  セルフリーサイエンス
- Industrial Property Number
  2004-304925
- Filing Date
  2003-10-20
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209013
[Presentation] Atypical protein kinase C isoform，aPKCλ，regulates directional cell migration during wound healing2017
- Author(s)
  Shin-Ichi Osada，Natsuko Noguchi，Tomonori Hirose，Tomoko Suzuki，Masami Kagaya，Kazuhiro Chida，Shigeo Ohno and Motomu Manabe
- Organizer
  日本研究皮膚科学会第42回年次学術大会・総会
- Data Source
  KAKENHI-PROJECT-15K09755
[Presentation] Differential rules of atypical protein kinase C isoforms in wound healing2017
- Author(s)
  Shin-Ichi Osada，Natsuko Noguchi，Tomonori Hirose，Tomoko Suzuki，Masami Kagaya，Kazuhiro Chida，Shigeo Ohno and Motomu Manabe
- Organizer
  47th Annual European Society for Dermatological Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09755
[Presentation] Differential Regulation of wound healing by atypical protein kinase C isoforms．2017
- Author(s)
  Natsuko Noguchi，Shin-Ichi Osada，Tomonori Hirose，Tomoko Suzuki，Masami Kagaya，Kazuhiro Chida，Shigeo Ohno and Motomu Manabe
- Organizer
  第31回表皮細胞研究会
- Data Source
  KAKENHI-PROJECT-15K09755
[Presentation] A cell polarity protein，aPKCλ，regulates hair follicle regeneration after wounding．2017
- Author(s)
  Shin-Ichi Osada，Natsuko Noguchi，Tomonori Hirose，Tomoko Suzuki，Masami Kagaya，Kazuhiro Chida，Shigeo Ohno and Motomu Manabe
- Organizer
  10th World Congress for Hair Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09755
[Presentation] 細胞の形と運命をつなぐメカニズム：細胞極性タンパク質.2016
- Author(s)
  大野茂男
- Organizer
  平成27年度　文部科学省　新学術領域研究　がん研究分野の特性等を踏まえた支援活動　公開シンポジウム
- Place of Presentation
  一橋講堂　学術総合センター2F(東京都千代田区)
- Year and Date
  2016-02-08
- Data Source
  KAKENHI-PLANNED-23112003
[Presentation] 細胞のランドマークを掘る.2015
- Author(s)
  大野　茂男
- Organizer
  日本学術振興会　学術システム研究センター　生物系科学専門調査班ＯＢＯＧセミナー　第4回・生物系科学における学術研究の動向を探る
- Place of Presentation
  丸駒温泉旅館(北海道千歳市)
- Year and Date
  2015-01-11
- Invited
- Data Source
  KAKENHI-PLANNED-23112003
[Presentation] スフィアアッセイを用いた乳腺組織幹細胞の解析.2015
- Author(s)
  高柳亜由美, 佐々木和教, 秋本和憲, 大野茂男
- Organizer
  第５９回日本薬学会関東支部大会
- Place of Presentation
  日本大学薬学部(千葉県船橋市)
- Year and Date
  2015-09-12
- Data Source
  KAKENHI-PLANNED-23112003
[Presentation] 一次繊毛におけるヘッジホッグ・シグナル伝達系の調節機構に対する細胞極性制御因子の関係.2015
- Author(s)
  廣瀬智威, 風間宏美, 藤田龍平, 大野茂男
- Organizer
  BMB2015（第38回日本分子生物学会年会、第88回日本生化学会大会合同大会）
- Place of Presentation
  神戸ポートアイランド(兵庫県神戸市)
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PLANNED-23112003
[Presentation] The roles of aPKC on the maintenance of mammary tubular structure.2015
- Author(s)
  大野茂男
- Organizer
  新学術領域研究「上皮管腔組織形成」第２回国際シンポジウム
- Place of Presentation
  北海道大学医学部学友会館「フラテ」大ホール (北海道札幌市)
- Year and Date
  2015-08-22
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23112003
[Presentation] A cell polarity protein, aPKCλ, is essential for hair follicle stem cell quiescence2015
- Author(s)
  Osada S, Minematsu N, Oda F, Akimoto K, Kawana S, Ohno S
- Organizer
  第３８回分子生物学会年会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K09755
[Presentation] 上皮細胞特有のアクチン骨格によるYAP/TAZの制御機構を介した増殖制御機構.2015
- Author(s)
  古川可奈, 山下和成, 大野茂男
- Organizer
  BMB2015（第38回日本分子生物学会年会、第88回日本生化学会大会合同大会）
- Place of Presentation
  神戸ポートアイランド(兵庫県神戸市)
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PLANNED-23112003
[Presentation] 細胞極性因子aPKCλは毛包幹細胞の維持に必要である2014
- Author(s)
  長田真一，峰松直子，小田文乃，秋本和憲，川名誠司，眞鍋　求，大野茂男
- Organizer
  第22回毛髪科学研究会
- Place of Presentation
  東京
- Year and Date
  2014-11-29
- Data Source
  KAKENHI-PROJECT-24591669
[Presentation] 細胞極性制御の翻訳後修飾異常と疾患.2014
- Author(s)
  大野　茂男
- Organizer
  文部科学省イノベーションシステム整備事業　先端融合領域イノベーション創出拠点形成プログラム「翻訳後修飾プロテオミクス医療研究拠点の形成」　第5回公開シンポジウム　進む新しい医療研究拠点の形成
- Place of Presentation
  県民共済みらいホール (神奈川県横浜市)
- Year and Date
  2014-08-19
- Data Source
  KAKENHI-PLANNED-23112003
[Presentation] aPKC suppresses the growth of mammary luminal progenitors through a novel mechanism involving ErbB2.2014
- Author(s)
  Ohno S
- Organizer
  14th Japanese-German Cancer Workshop
- Place of Presentation
  Charite Comprehensive Cancer Center (Berlin,Germany)
- Year and Date
  2014-11-15
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23112003
[Presentation] Regulation of epithelial cell polarity by PAR3 depends on Girdin transcription and Girdin-Galphai3 signaling.2014
- Author(s)
  Ohno S
- Organizer
  COLD SPRING HARBOR ASIA CONFERENCES Dynamics of Cellular Behavior During Development and Disease,
- Place of Presentation
  Grand Dushu Lake hotel(Suzhou,China)
- Year and Date
  2014-11-17
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23112003
[Presentation] aPKCλ maintains the integrity of the glomerular slit diaphragm through trafficking of nephrin to the cell surface.2014
- Author(s)
  Ohno S
- Organizer
  The Fourth Shanghai International Forum on Acute and Chronic Kidney Injury
- Place of Presentation
  Renaissance Pudong Hotel (Shanghai,China)
- Year and Date
  2014-10-24
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23112003
[Presentation] The Roles of aPKCλin Maintaining Epidermal Homeostasis2014
- Author(s)
  長田真一，峰松直子，小田文乃，秋本和憲，川名誠司，眞鍋　求，大野茂男
- Organizer
  第38回表皮細胞研究会
- Place of Presentation
  鹿児島
- Year and Date
  2014-12-06
- Data Source
  KAKENHI-PROJECT-24591669
[Presentation] aPKC suppresses the growth of mammary luminal progenitors through a novel mechanism involving ErbB2.2014
- Author(s)
  大野　茂男
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜 (神奈川県横浜市)
- Year and Date
  2014-09-26
- Invited
- Data Source
  KAKENHI-PLANNED-23112003
[Presentation] Atypical PKC connects cell polarity and cancer.2014
- Author(s)
  Ohno S
- Organizer
  Federation of American Societies for Experimental Biology
- Place of Presentation
  Steamboat Grand Resort(Steamboat Springs,Colorado,USA )
- Year and Date
  2014-07-28
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23112003
[Presentation] Formation of mRNA surveillance complex during aberrant termination recognition.2013
- Author(s)
  Yamashtia A, Uchiyama A, Kataoka N, Kurosawa H, Nakamura Y, Ohno S
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド(兵庫県神戸市)
- Year and Date
  2013-12-04
- Data Source
  KAKENHI-PLANNED-23112003
[Presentation] An efficient affinity purification method for interaction proteomics in mammalian cells.2013
- Author(s)
  Yamashita A, Kurosawa H, Hirano H, Ohno S
- Organizer
  HUPO 12th Annual World Congress
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2013-09-16
- Data Source
  KAKENHI-PLANNED-23112003
[Presentation] The molecular mechanism by which Lgl, the aPKC-interacting protein, suppress cell proliferation.2013
- Author(s)
  Yamashita K, Ide M, Furukawa K, Suzuki A, Hirano H, Ohno S
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド(兵庫県神戸市)
- Year and Date
  2013-12-04
- Data Source
  KAKENHI-PLANNED-23112003
[Presentation] p50 stabilizes the cell surface E-cadherin and regulates development and maturation of tight Junctions through the PAR complex.2013
- Author(s)
  Fujikawa Y, Harita Y, Hirose T, Yamashita A, Sasaki K, Hirano H, Ohno S
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド(兵庫県神戸市)
- Year and Date
  2013-12-05
- Data Source
  KAKENHI-PLANNED-23112003
[Presentation] MTCL1 plays an essential role in polarized clustering of the Golgi complex through its microtubule crosslinking and stabilizing activity.2013
- Author(s)
  Sato Y, Hayashi K, Amano Y, Takahashi M, Yonemura S, Hayashi I, Ohno S, Suzuki A
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド(兵庫県神戸市)
- Year and Date
  2013-12-04
- Data Source
  KAKENHI-PLANNED-23112003
[Presentation] aPKC suppresses the growth of mammary luminal progenitors through a novel mechanism involving ErbB2.2013
- Author(s)
  Ohno S
- Organizer
  新学術領域研究「上皮管腔組織形成」第一回国際シンポジウム the first International Meeting for Epithelial tubulology
- Place of Presentation
  北海道大学　学術交流会館(北海道札幌市)
- Year and Date
  2013-06-22
- Data Source
  KAKENHI-PLANNED-23112003
[Presentation] 正常乳腺上皮細胞前駆細胞と乳がん幹細胞の細胞分離技術と解析.2012
- Author(s)
  秋本和憲, 佐々木和教, 中谷雅明, 大野茂男
- Organizer
  新学術領域研究「上皮管腔組織形成」第2回技術講習会
- Place of Presentation
  先端医療センター研究棟１階BD神戸ラボ(兵庫県神戸市)
- Data Source
  KAKENHI-PLANNED-23112003
[Presentation] 細胞極性タンパク質PAR-3による遺伝子発現制御を介した、上皮細胞極性の分子機構.2012
- Author(s)
  佐々木和教, 角和　卓, 秋本和憲, 古閑比佐志, 大野茂男
- Organizer
  平成24年度科研費新学術領域研究「がん若手ワークショップ」
- Place of Presentation
  蓼科グランドホテル滝の湯(長野県茅野市)
- Data Source
  KAKENHI-PLANNED-23112003
[Presentation] 神経幹前駆細胞の運命決定に対するPAR3の機能解析.2012
- Author(s)
  廣瀬智威, 杉谷善信, 日下智保, 野田哲生, 大野茂男
- Organizer
  新学術領域「大脳新皮質構築」平成24年度夏の班会議、及び2012年度包括脳ネットワーク夏のワークショップ
- Place of Presentation
  仙台国際センター(宮城県仙台市）
- Data Source
  KAKENHI-PLANNED-23112003
[Presentation] Specific inhibition of SMG-8 rescues effectively the mutant phenotypes exacerbated by nonsense-mediated mRNA decay without cell toxicity.2012
- Author(s)
  Yamashita A, Usuki F, Ohno S
- Organizer
  2012 CSHL Meeting on Translational Control
- Place of Presentation
  Cold Spring Harbor Laboratory（NY, USA）
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] A Novel Microtubule Binding Protein, MARKAP1, Regulates Stability of the Golgi-Nucleated Microtubules and Directional Cell Migration.2012
- Author(s)
  Satoh Y, Hayashi K, Amano Y, Takahashi M, Hayashi I, Ohno S, Suzuki A
- Organizer
  American Society for Cell Biology ( ASCB) 2012 Annual Meeting
- Place of Presentation
  Moscone Center, San Francisco(San Francisco, USA)
- Data Source
  KAKENHI-PLANNED-23112003
[Presentation] 上皮組織の形成と維持における極性タンパク質の役割2012
- Author(s)
  大野茂男
- Organizer
  第117回日本解剖学会総会・全国学術集会、シンポジウム、細胞極性化の原理と整理機能
- Place of Presentation
  甲府
- Year and Date
  2012-03-28
- Data Source
  KAKENHI-PROJECT-23659174
[Presentation] 細胞極性制御因子aPKCによる乳腺上皮前駆細胞の増殖制御と乳がんにおけるその破綻.2012
- Author(s)
  秋本和憲, 長嶋洋治, 石黒　斉, 鄭　允文, 佐々木和教, 谷口英樹, 野田哲生, 大野茂男
- Organizer
  第３０回日本ヒト細胞学会学術集会シンポジウム
- Place of Presentation
  梅田スカイビル(大阪府）
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] Epithelial cell polarity and the PAR-aPKC complex2012
- Author(s)
  Ohno S
- Organizer
  Molecular Structure and Function of the Apical Junctional Complex in Epithelia and Endothelia
- Place of Presentation
  Merida, Mexico.
- Year and Date
  2012-11-02
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] Integrated regulation of PIKK-mediated stress responses by AAA+ proteins RUVBL1 and RUVBL22012
- Author(s)
  Ohno S
- Organizer
  First International Workshop on Pontin (RUVBL1) and Reptin (RUVBL2)
- Place of Presentation
  Bordeaux, France
- Year and Date
  2012-10-18
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] 細胞極性化の原理と生理機能2012
- Author(s)
  大野茂男
- Organizer
  第117回解剖学会総会・全国学術集会
- Place of Presentation
  山梨大学甲府キャンパス(山梨県).
- Year and Date
  2012-03-28
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] Signaling Crosstalk between Cell Polarity and Cell Growth/Apoptosis2012
- Author(s)
  Ohno S
- Organizer
  第33回日本分子生物学会年会第83回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド(兵庫県).
- Year and Date
  2012-12-07
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] The regulators and the effectors of the aPKC-PAR.2012
- Author(s)
  Ohno S
- Organizer
  The regulators and the effectors of the aPKC-PAR. SFB Symposium 2012 "Molecular Cell Dynamics"
- Place of Presentation
  Munster, Germany.
- Year and Date
  2012-06-01
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] 細胞極性制御因子aPKCによる乳腺上皮前駆細胞の増殖制御と乳がんにおけるその破綻.2012
- Author(s)
  秋本和憲, 長嶋洋治, 石黒　斉, 鄭　允文, 佐々木和教, 谷口英樹, 野田哲生, 大野茂男
- Organizer
  第３０回日本ヒト細胞学会学術集会シンポジウム
- Place of Presentation
  梅田スカイビル(大阪府大阪市)
- Data Source
  KAKENHI-PLANNED-23112003
[Presentation] A Novel Microtubule Binding Protein, MARKAP1, Regulates Stability of the Golgi-Nucleated Microtubules and Directional Cell Migration.2012
- Author(s)
  Satoh Y, Hayashi K, Amano Y, Takahashi M, Hayashi I, Ohno S, Suzuki A
- Organizer
  American Society for Cell Biology ( ASCB) 2012 Annual Meeting
- Place of Presentation
  Moscone Center, San Francisco（San Francisco, USA）
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] Epithelial cell polarity and the Par-aPKC complex2011
- Author(s)
  Ohno S
- Organizer
  5th International Epithelial-Mesenchymal Transition Meeting
- Place of Presentation
  Biopolis, Singapore
- Year and Date
  2011-10-13
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] Cell polarity and the maintenance and disruption of epithelial tissues2011
- Author(s)
  Ohno S
- Organizer
  US-Japan Summer Conference on Cancer
- Place of Presentation
  Duarte, CA, USA.
- Year and Date
  2011-08-05
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] Molecular mechanisms regulating the turnover of nephrin ; the role of cell polarity regulator, aPKC2011
- Author(s)
  Satoh D, Harita Y, Daimon C, Hirose T, Kurihara H, Ohno S
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-23659174
[Presentation] Molecular mechanisms regulating the turnover of nephrin ; the role of cell polarity regulator, aPKC2011
- Author(s)
  Satoh D, Harita Y, Daimon C, Hirose T, Kurihara H, Ohno S
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-23659174
[Presentation] Cell polarity and cancer. 2011 International Symposium on Infectious Disease and Signal Transduction2011
- Author(s)
  Ohno S
- Organizer
  2011 Taiwan-Japan Joint Symposium on Cell Signaling and Gene Regulation
- Place of Presentation
  Tainan City, Taiwan
- Year and Date
  2011-11-20
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] ASPP2 regulates epithelial cell polarity through the PAR complex.2010
- Author(s)
  Ohno S
- Organizer
  The 50th American Society for Cell Biology Annual Meeting
- Place of Presentation
  Philadelphia, USA(招待講演)
- Year and Date
  2010-12-15
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] 細胞極性制御因子aPKCλによる上皮前駆細胞の増殖制御とその破綻2010
- Author(s)
  秋本和憲, 鄭允文, 長嶋洋治, 石黒斉, 佐々木和教, 金民大, 李斌, 角和卓, 谷口英樹, 野田哲生, 大野茂男
- Organizer
  第33回日本分子生物学会年会第83回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] Inside-out signalling effects on extracellular membrane and polarity2010
- Author(s)
  Ohno S
- Organizer
  The 8th International Podocyte Conference
- Place of Presentation
  Bristol, UK
- Year and Date
  2010-06-08
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] Regulation of Girdin/GIV/Ccdc88A expression by PAR-3 is required for establishment of epithelial cell polarity.2010
- Author(s)
  Sasaki K, Ohno S
- Organizer
  The 69th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Osaka International Convention Center
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] Regulatory mechanism of kinesin-1 motor activity through JIP1.2010
- Author(s)
  Satake T, Hirano H, Yamanaka Y, Ohno S, Hirai S-I
- Organizer
  第33回日本分子生物学会年会第83回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] 細胞極性によるHippo経路の抑制がマウス着床前胚における位置依存的な細胞分化をつかさどる2010
- Author(s)
  平手良和, 平原志乃, 井上健一, 中尾和貴, 鈴木厚, 秋本和憲, 大野茂男, 平井孝明, 千田和広, Marikawa Y, Vernadeth A, 佐々木洋
- Organizer
  第33回日本分子生物学会年会第83回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド(ポスター発表)
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] The cell polarity proteins, aPKC-Par complex, regulate the turnover of nephrin to maintain slit diaphragm integrity.2010
- Author(s)
  Satoh D, Harita Y, Daimon C, Hirose T, Ohno S
- Organizer
  AMERICAN SOCIETY OF NEPHROLOGY Renal Week 2010
- Place of Presentation
  Colorado, USA
- Year and Date
  2010-11-19
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] Maintenance of dendritic spine morphology by PAR1b through regulation of microtubule dynamics.2010
- Author(s)
  林健二, 鈴木厚, 大野茂男
- Organizer
  第33回日本分子生物学会年会第83回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] 細胞極性によるHippo経路の抑制がマウス着床前胚における位置依存的な細胞分化をつかさどる2010
- Author(s)
  平手良和, 平原志乃, 井上健一, 中尾和貴, 鈴木厚, 秋本和憲, 大野茂男, 平井孝明, 千田和広, Marikawa Y, Vernadeth A, 佐々木洋
- Organizer
  第33回日本分子生物学会年会第83回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド(口頭発表)
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] 新規PAR1結合タンパク質p250は, 微小管安定化タンパク質である2010
- Author(s)
  鈴木厚, 佐藤由典, 秋津真志, 天野芳子, 大野茂男
- Organizer
  第62回日本細胞生物学会大会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2010-05-20
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] Signaling Crosstalk between Cell Polarity and Cell Growth/Apoptosis.2010
- Author(s)
  Ohno S
- Organizer
  第33回日本分子生物学会年会第83回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド(招待講演)
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] Inside-out signalling effects on extracellular membrane and polarity.2010
- Author(s)
  Ohno S
- Organizer
  The 8th International Podocyte Conference
- Place of Presentation
  Bristol UK(招待講演)
- Year and Date
  2010-06-08
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] Apoptosis-Stimulating Protein of p53 (ASPP2) isinvolved in the PAR Complex to Regulate Epithelial Cell Polarity.2010
- Author(s)
  叢偉立, 廣瀬智威, 山下暁朗, 水野恵子, 張田豊, 平野久, 大野茂男
- Organizer
  第62回日本細胞生物学会大会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2010-05-19
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] aPKC and IL-6 expression in prostate cancer tissues.2010
- Author(s)
  Ishiguro H, Akimoto K, Nagashima Y, Kagawa E, Sasaki T, Sano J, Takagawa R, Sasaki K, Fujinami K, Aoki I, Ohno S, Kubota Y, Uemura H
- Organizer
  The 69th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Osaka International Convention Center
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] 微量RNAからの次世代シークエンスライブラリー構築法の改善2010
- Author(s)
  馬場しほ, 山下暁朗, 大野茂男
- Organizer
  第33回日本分子生物学会年会第83回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] KIBRA suppresses apical exocytosis through inhibition of aPKC kinase activity in epithelial cells.2010
- Author(s)
  Yoshihama Y, Sasaki K, Horokoshi Y, Ohtsuka T, Hakuno F, Takahashi S-I, Suzuki A, Ohno S, Chida K
- Organizer
  The 50th American Society for Cell Biology Annual Meeting
- Place of Presentation
  Philadelphia, USA
- Year and Date
  2010-12-14
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] KIBRA suppresses apical exocytosis through inhibition of aPKC kinase activity in epithelial cells.2010
- Author(s)
  Yoshihama Y, Sasaki K, Horokoshi Y, Ohtsuka T, Hakuno F, Takahashi S-I, Suzuki A, Ohno S, Chida K
- Organizer
  第33回日本分子生物学会年会第83回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] Axon formation in neocortical neurons depends on the stage-specific stabilization of microtubules by DLK-JNK pathway.2010
- Author(s)
  Hirai S-I, Banba Y, Satake T, Ohno S
- Organizer
  第33回日本分子生物学会年会第83回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] mRNA品質管理機構制御因子SMG-1の構想と生理機能2010
- Author(s)
  山下暁朗, Ernesto A P, Israel F S, 番場由美, 星野耕二, 上村博司, Oscar L I, 大野茂男
- Organizer
  第33回日本分子生物学会年会第83回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] 細胞シグナリングと疾患モデルのプロテオミクス第7回大会2009
- Author(s)
  大野茂男
- Organizer
  日本ヒトプロテオーム機構(JHUPO)
- Place of Presentation
  東京
- Year and Date
  2009-07-27
- Data Source
  KAKENHI-PROJECT-17014076
[Presentation] 細胞シグナリングと疾患モデルのプロテオミクス2009
- Author(s)
  S.Ohno
- Organizer
  日本ヒトプロテオーム機構(JHUPO)第7回大会
- Place of Presentation
  北里大学薬学部(東京都)
- Year and Date
  2009-07-27
- Data Source
  KAKENHI-PROJECT-16060101
[Presentation] Epithelial Cell Polarity and the PAR-aPKC System2009
- Author(s)
  Ohno, S.
- Organizer
  The seventh annual CDB Symposium "Shape and Polarity" RIKEN
- Place of Presentation
  Kobe
- Year and Date
  2009-03-23
- Data Source
  KAKENHI-PROJECT-16060101
[Presentation] 細胞シグナリングと疾患モデルのプロテオミクス2009
- Author(s)
  大野茂男
- Organizer
  日本ヒトプロテオーム機構第7回大会
- Place of Presentation
  北里大学薬学部(東京都)
- Year and Date
  2009-07-27
- Data Source
  KAKENHI-PROJECT-16060101
[Presentation] Possible involvement of PAR-3 in the regulation of slit diaphragm through the direct interaction with Nephrin2008
- Author(s)
  Satoh D, Hirose T, Kurihara H, Ohno S
- Organizer
  The 7th International Podocyte Conference
- Place of Presentation
  Toronto, Canada
- Data Source
  KAKENHI-PROJECT-17014076
[Presentation] The cell polarity protein aPKCλ plays a critical role in the maintenance of podocyte slit diaphragms2008
- Author(s)
  Hirose T, Satoh D, Kurihara H, Akimoto K, Matsusaka T, Ichikawa I, Noda, T, Ohno S
- Organizer
  The 7th International Podocyte Conference
- Place of Presentation
  Toronto, Canada
- Data Source
  KAKENHI-PROJECT-17014076
[Presentation] Conditional depletion of aPKCλ in eye lens causes microphthalmia and cataract2008
- Author(s)
  Sugiyama Y, Akimoto K, Robinson M. L, Quinlan, R. A, Ohno S
- Organizer
  ARVO (Association for Research in Vision and Ophthalmology) 2008Annual Meeting, 2008
- Place of Presentation
  Florida USA
- Data Source
  KAKENHI-PROJECT-17014076
[Presentation] The formation of SMG-1 : Upfl : eRF1 : eRF3 complex (SURF) on ribosomes precedes translation-dependent-Upfl phosphorylation during nonsense-medi ated mRNA decay2008
- Author(s)
  Yamashita A, Kashima I, Izumi N, Katsuhata Y, Muramatsu R, Ohno S
- Organizer
  THE 21st NAITO CONFERENCE"Nuclear Dynamics and RNA[I]"
- Place of Presentation
  Yamanashi, Japan
- Data Source
  KAKENHI-PROJECT-17014076
[Presentation] The cell polarity protein, aPKClambda, plays a critical rolein the maintenance of podocyte slit diaphragms, specific type if epithelial intercellular junctions2008
- Author(s)
  Hirose T, Satoh D, Kurihara H, kusaka C, Hirose H, Akimoto K, Matsusaka T, Ichikawa I, Noda T, Ohno S
- Organizer
  BMB2008
- Place of Presentation
  Kobe
- Data Source
  KAKENHI-PROJECT-17014076
[Presentation] Translation Termination Complex During Nonsense-Mediated MRNA Decay2008
- Author(s)
  Yamashita A, Izumi N, Kashima I, Katsuhata Y, Muramatsu R, Ohno S
- Organizer
  2008 Cold spring harver labatory meeting on translational control
- Place of Presentation
  New York, USA
- Data Source
  KAKENHI-PROJECT-17014076
[Presentation] Conditionally Replicative Adenoviral Vectors for the Treatment of Gastric Cancer2008
- Author(s)
  Kosaka T, Ono H, Kunisaki C, Julia D, Ohno S, Yamamoto M, Shimada H
- Organizer
  The 67th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Nagoya
- Data Source
  KAKENHI-PROJECT-17014076
[Presentation] The role of aPKC lambda in prostate cancer progression2008
- Author(s)
  Ishiguro H, Akimoto K, Nagashima Y, Kojima Y, Ishiguro Y, Sasaki T, Umemura H, Ohno S, Kubota Y
- Organizer
  The 67th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Nagoya
- Data Source
  KAKENHI-PROJECT-17014076
[Presentation] aPKC1 regulates mammary-gland morphogenesis through the transcriptiona 1 suppression of ErbB2/HER-2 gene2008
- Author(s)
  Akimoto K, Nagashima K, Ishiguro H, Kojima Y, Kim M, Sasaki K, Noda T, Ohno S
- Organizer
  Second JCA-AACR Special Joint Conference, The Latest Advances in Breast Cancer Research : From Basic Science to Therapeutics
- Place of Presentation
  Awaji, Hyogo, Japan
- Data Source
  KAKENHI-PROJECT-17014076
[Presentation] The SMG-1:SMG-8:p60 Complex Regulated Phosphorylation OF Upf1 Is Required For The Dissociation Of eRFs From mRNA Surveillance Complex During Nonsense-mediated mRNA decay2007
- Author(s)
  Yamashita A, Kashima I, Izumi N, Ohnishi T, Anderson P, Ohno S.
- Organizer
  第12回国際RNA学会年会
- Place of Presentation
  University of Wisconsin,Madison
- Year and Date
  2007-06-03
- Data Source
  KAKENHI-PROJECT-17014076
[Presentation] The SMG-1:SMG-8:p60 Complex Regulated Phosphorylation Of Upf1Is Repuired For The Dissociation Of eRFs From mRNA Surveillance Complex During Nonsense-mediated mRNA decay2007
- Author(s)
  Yamashita A, Izumi N, Kashima I, Ohnishi T, Amderson P, Ohno S.
- Organizer
  第9回日本RNA学会年会
- Place of Presentation
  名古屋
- Year and Date
  2007-07-28
- Data Source
  KAKENHI-PROJECT-17014076
[Presentation] The role of PAR1/MARK polarity kinase in the interaction between Heli civacter pylori CagA and SHP2 oncoprotein2007
- Author(s)
  紙谷尚子, Iraj Saadat, 東秀明, 小布施力史, 梅田真由美, 齊藤康弘, Huaischeng Lu, 大西なおみ, 東健, 鈴木厚, 大野茂男, 畠山昌則
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-17014076
[Presentation] The role of the PAR-aPKC complex in epithelial morphogenesis and tum origenesis2007
- Author(s)
  大野茂男
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-17014076
[Presentation] Defective cell polarity in kidney podocytes causes severe glomerular disease2007
- Author(s)
  Hirose T, Satoh D, Kuriharawa I, Noda T, Ohno S
- Organizer
  Yokohama City University 21st Century COE Program, Cell Polarity 2007-International symposium on CellPolarity Ststem and Future Medicine
- Place of Presentation
  Hayamn
- Year and Date
  2007-12-09
- Data Source
  KAKENHI-PROJECT-17014076
[Presentation] Polarity protein PAR-1b regulates extracellular laminin organization through regulation of the utrophin-dystroglycan complex2007
- Author(s)
  Suzuki A, Amano Y, Yamashita K, Ohno S
- Organizer
  Yokchama Ciyt University 21st Century COEProgram Cell Polarity2007-International Symposium, Cell Polarity System and Future Medicine
- Place of Presentation
  Hayama
- Year and Date
  2007-12-10
- Data Source
  KAKENHI-PROJECT-17014076
[Presentation] 細胞極性タンパク質、PAR-1bはユーロフィン・ジストログカン複合体制御することを介して細胞外ラミニンの集積を制御している2007
- Author(s)
  鈴木厚、山下和成、大野茂男
- Organizer
  BMB2007-第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-11
- Data Source
  KAKENHI-PROJECT-17014076
[Presentation] Defective cell polarity in kidney podocytes causes severe glomerular disease2007
- Author(s)
  Hirose, T.
- Organizer
  Yokohama City University 21st Century COE Program, Cell Polarity 2007-International Symposium on Cell Polarity System and Future Medicine
- Place of Presentation
  Hayama, Kanagawa
- Year and Date
  2007-12-09
- Data Source
  KAKENHI-PROJECT-16060101
[Presentation] mRNAの品質鹽機構〜分子機構とその振作技術の物学・医学への展開〜2007
- Author(s)
  大野茂男
- Organizer
  日本生化学北陸支部会
- Place of Presentation
  金沢
- Year and Date
  2007-05-26
- Data Source
  KAKENHI-PROJECT-17014076
[Presentation] A novel signaling pathway by which PAR-aPKC system regulates cell-substate interaction2007
- Author(s)
  鈴木厚、山下和成、天野芳子、大野茂男
- Organizer
  第40回日本発生生物学会, 第59回細胞生物学会合同大会シンポジウム
- Place of Presentation
  福岡
- Year and Date
  2007-05-30
- Data Source
  KAKENHI-PROJECT-17014076
[Presentation] Par-1結合タンパク質p250は、微小管の結束化および安定化に関与するタンパク質である.
- Author(s)
  佐藤由典, 秋津真志, 林健二, 天野芳子, 大野茂男, 鈴木厚
- Organizer
  第63回日本細胞生物学会大会
- Place of Presentation
  北海道大学　クラーク会館、学術交流会館(北海道)
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] SMG-1, PIKK Family Kinase, Regulates mRNA Surveillance.
- Author(s)
  Yamashita A, Kurosawa H, Ohno S
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡（福岡県）
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] The nuclear localization and overexpression of atypical protein kinase C in cervical cancer correlate with prognosis.
- Author(s)
  Mizushima　T, Akimoto K, Nagashima Y, Mogami T, Sato M, Miyagi E, Kameda Y, Inayama Y, Ohashi K, Aoki I, Ohno S, Hirahara F
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌、さっぽろ芸術館、札幌市教育文化会館（北海道）
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] A new microtubule binding protein, p250, regulates the directional migration of epithelial cells.
- Author(s)
  佐藤由典, 秋津真志, 林健二, 天野芳子, 林郁子, 大野茂男, 鈴木厚
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] Prognostic impact of aPKC λ/ι expression in pancreatic cancer.
- Author(s)
  Kato S, Akimoto K, Nagashima Y, Ishiguro H, Kobayashi N, Maeda S, Ohno S, Nakajima A
- Organizer
  70th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  名古屋国際会議場（愛知県）
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] p50 Regulates Epithelial Cell Polarity by Inhibiting E-cadherin endocytosis.
- Author(s)
  Fujikawa Y, Hirose T, Harita Y, Sasaki K, Yamashita K, Yamashita A, Hirano H, Ohno S
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡(福岡県福岡市)
- Data Source
  KAKENHI-PLANNED-23112003
[Presentation] Analysis of Physiological Function of MARKAP1 in the Cerebellum.
- Author(s)
  Satake T, Hayashi K, Yamashita K, Satoh Y, Ohno S, Suzuki A
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡(福岡県福岡市)
- Data Source
  KAKENHI-PLANNED-23112003
[Presentation] JNK Facilitates the Formation of Epithelial Cell Sheet.
- Author(s)
  Furukawa K, Ohno S, Hirai S-I
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡(福岡県福岡市)
- Data Source
  KAKENHI-PLANNED-23112003
[Presentation] The regulators and the effectors of the aPKC-PAR.
- Author(s)
  Ohno S
- Organizer
  SFB Symposium 2012 "Molecular Cell Dynamics"
- Place of Presentation
  Max Planck Institut（ミュンスター, Germany)
- Invited
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] 限外濾過膜としてのスリット膜のターンオーバーとそのメカニズム.
- Author(s)
  佐藤大輔, 張田豊, 大門主税, 栗原秀剛, 廣瀬智威, 大野茂男
- Organizer
  第100回東京腎生理集談会
- Place of Presentation
  獨協医科大学（東京都）
- Data Source
  KAKENHI-PLANNED-23112003
[Presentation] Epithelial cell polarity and the PAR-aPKC complex.
- Author(s)
  Ohno S
- Organizer
  Molecular Structure and Function of the Apical Junctional Complex in Epithelia and Endothelia
- Place of Presentation
  Hyatt Regency(Merida, Mexico)
- Invited
- Data Source
  KAKENHI-PLANNED-23112003
[Presentation] Epithelial cell polarity and the Par-aPKC complex.
- Author(s)
  Ohno S
- Organizer
  5th International Epithelial-Mesenchymal Transition Meeting
- Place of Presentation
  College of Medicine, National Cheng Kung University.Taipei Medical University（Biopolis, Singapore）
- Invited
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] Maintenance of Dendritic Spine Morphology by PAR1b through Regulation of Microtubule Growth.
- Author(s)
  Hayashi K, Suzuki A, Hoogenraad C. C, Ohno S
- Organizer
  2011 The American Society for Cell Biology Annual Meeting
- Place of Presentation
  Colorado Convention Center（Denver, Colorado, USA）
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] Epithelial cell polarity and the Par-aPKC complex.
- Author(s)
  Ohno S
- Organizer
  5th International Epithelial-Mesenchymal Transition Meeting
- Place of Presentation
  College of Medicine, National Cheng Kung University.Taipei Medical University.(Biopolis, Singapore)
- Invited
- Data Source
  KAKENHI-PLANNED-23112003
[Presentation] ガン抑制遺伝子Lglは、VprBPと結合することによって、単層の上皮構造を維持している.
- Author(s)
  山下和成, 井出真理子, 村松玲子, 鈴木厚, 平野久, 大野茂男
- Organizer
  第63回日本細胞生物学会大会
- Place of Presentation
  北海道大学　クラーク会館、学術交流会館（北海道）
- Data Source
  KAKENHI-PLANNED-23112003
[Presentation] A novel microtubule binding protein, MARKAP1, cooperates with PAR-1 for the development of the lateral microtubule bundles in epithelial cells.
- Author(s)
  Akitsu M, Satoh Y, Amano Y, Yamashita K, Yamashita A, Maki T, Hayashi I, Hirano H, Ohno S, Suzuki A
- Organizer
  American Society for Cell Biology ( ASCB) 2012 Annual Meeting
- Place of Presentation
  Moscone Center, San Francisco（San Francisco, USA）
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] 乳腺前駆細胞の増殖を制御する新規aPKC-ErbB2枢軸.
- Author(s)
  大野茂男
- Organizer
  平成24年度文部科学省新学術領域研究、がん研究分野の特性等を踏まえた支援活動、公開シンポジウム
- Place of Presentation
  学術総合センター(東京都千代田区)
- Invited
- Data Source
  KAKENHI-PLANNED-23112003
[Presentation] aPKC λ regulates mammary luminal progenitor cell propagation and it’s disruption in a subpopulation of breast cancer.
- Author(s)
  Akimoto K, Nagashima Y, Ishiguro H, Zheng Y-W, Sasaki K, Kojima Y, Taniguchi H, Ohno S
- Organizer
  70th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  名古屋国際会議場（愛知県）
- Data Source
  KAKENHI-PLANNED-23112003
[Presentation] Cell polarity and the maintenance and disruption of epithelial tissues.
- Author(s)
  Ohno S
- Organizer
  US-Japan Summer Conference on Cancer, Diabetes and Inflammation
- Place of Presentation
  Beckman Center Lecture Hall（Duarte, CA, USA）
- Invited
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] IL-6 遺伝子発現における mRNA 転写後制御機構の解析.
- Author(s)
  安部開人, 山下暁朗, Ann-Bin Shyu, 石上友章, 大野茂男, 梅村敏
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] Integrated regulation of PIKK-mediated stress responses by AAA+ proteins RUVBL1 and RUVBL2.
- Author(s)
  Ohno S
- Organizer
  First International Workshop on Pontin (RUVBL1) and Reptin (RUVBL2)
- Place of Presentation
  The European Institute for Chemistry and Biology (IECB)（Bordeaux, France）
- Invited
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] Prognostic impact of aPKC λ/ι expression in pancreatic cancer.
- Author(s)
  Kato S, Akimoto K, Nagashima Y, Ishiguro H, Kobayashi N, Maeda S, Ohno S, Nakajima A
- Organizer
  70th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  名古屋国際会議場（愛知県）
- Data Source
  KAKENHI-PLANNED-23112003
[Presentation] A novel microtubule binding protein, MARKAP1, cooperates with PAR-1 for the development of the lateral microtubule bundles in epithelial cells.
- Author(s)
  Akitsu M, Satoh Y, Amano Y, Yamashita K, Yamashita A, Maki T, Hayashi I, Hirano H, Ohno S, Suzuki A
- Organizer
  American Society for Cell Biology ( ASCB) 2012 Annual Meeting
- Place of Presentation
  Moscone Center, San Francisco(San Francisco, USA)
- Data Source
  KAKENHI-PLANNED-23112003
[Presentation] A Novel Microtubule Binding Protein, MARKAP, plays essential roles for the Golgi-Ribbon Formation by Regulating Golgi-Nucleated Microtubules.
- Author(s)
  Satoh Y, Hayashi K, Amano Y, Maki T, Hayashi I, Ohno S, Suzuki A
- Organizer
  Joint Meeting of The 45th Annual Meeting of the Japanese Society of Developmental Biologists & The 64th Annual Meeting of the Japan Society for Cell Biology
- Place of Presentation
  Kobe International Conference Center.The Kobe Chamber of Commerce and Industry.(Kobe, Hyougo)
- Data Source
  KAKENHI-PLANNED-23112003
[Presentation] aPKC λ regulates mammary luminal progenitor cell propagation and it’s disruption in a subpopulation of breast cancer.
- Author(s)
  Akimoto K, Nagashima Y, Ishiguro H, Zheng Y-W, Sasaki K, Kojima Y, Taniguchi H, Ohno S
- Organizer
  70th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  名古屋国際会議場（愛知県）
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] MARKAP1 cooperates with PAR-1/MARK for development of epithelial polarity by regulating microtubule organization.
- Author(s)
  Akitsu M, Satoh Y, Amano Y, Ohno S, Suzuki A
- Organizer
  Joint Meeting of The 45th Annual Meeting of the Japanese Society of Developmental Biologists & The 64th Annual Meeting of the Japan Society for Cell Biology
- Place of Presentation
  Kobe International Conference Center.The Kobe Chamber of Commerce and Industry.(Kobe, Hyougo)
- Data Source
  KAKENHI-PLANNED-23112003
[Presentation] p50 Regulates Epithelial Cell Polarity by Inhibiting E-cadherin endocytosis.
- Author(s)
  Fujikawa Y, Hirose T, Harita Y, Sasaki K, Yamashita K, Yamashita A, Hirano H, Ohno S
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡（福岡県）
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] PAR-3 mediates the expression of Girdin/GIV/Ccdc88a to regulate epithelial cell polarity.
- Author(s)
  Sasaki K, Kakuwa T, Koga H, Ohno S
- Organizer
  US-Japan Conference on Inflammation, Diabetes and Cancer
- Place of Presentation
  Beckman Center Lecture Hall（Duarte, CA, USA）
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] PAR3 is required for restricting symmetric proliferative divisions in mouse neutral precursor cells.
- Author(s)
  Hirose T, Sugitani Y, Kusaka C, Noda T, Ohno S
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Data Source
  KAKENHI-PLANNED-23112003
[Presentation] Cell polarity and cancer.
- Author(s)
  Ohno S
- Organizer
  2011 International Symposium on Infectious Disease and Signal Transduction, 2011 Taiwan-Japan Joint Symposium on Cell Signaling and Gene Regulation
- Place of Presentation
  College of Medicine, National Cheng Kung University（Tainan City, Taiwan)
- Invited
- Data Source
  KAKENHI-PLANNED-23112003
[Presentation] The nuclear localization and overexpression of atypical protein kinase C in cervical cancer correlate with prognosis.
- Author(s)
  Mizushima　T, Akimoto K, Nagashima Y, Mogami T, Sato M, Miyagi E, Kameda Y, Inayama Y, Ohashi K, Aoki I, Ohno S, Hirahara F
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌、さっぽろ芸術館、札幌市教育文化会館(北海道札幌市)
- Data Source
  KAKENHI-PLANNED-23112003
[Presentation] 新規微小統合タンパク質MARKAP(PAR-1/MARK Associated protein)による、Golgi体のリボン構造形式の制御機構の解析.
- Author(s)
  佐藤由典, 林健二, 天野芳子, 高橋美樹子, 米村重信, 林郁子, 大野茂男, 鈴木厚
- Organizer
  第65回日本細胞生物学会大会
- Place of Presentation
  ウインクあいち(愛知県名古屋市)
- Year and Date
  2013-06-19 – 2013-06-21
- Data Source
  KAKENHI-PLANNED-23112003
[Presentation] MARKAP1 cooperates with PAR-1/MARK for development of epithelial polarity by regulating microtubule organization.
- Author(s)
  Akitsu M, Satoh Y, Amano Y, Ohno S, Suzuki A
- Organizer
  Joint Meeting of The 45th Annual Meeting of the Japanese Society of Developmental Biologists & The 64th Annual Meeting of the Japan Society for Cell Biology
- Place of Presentation
  Kobe International Conference Center.The Kobe Chamber of Commerce and Industry(兵庫県）
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] Par-1結合タンパク質p250は、微小管の結束化および安定化に関与するタンパク質である.
- Author(s)
  佐藤由典, 秋津真志, 林健二, 天野芳子, 大野茂男, 鈴木厚
- Organizer
  第63回日本細胞生物学会大会
- Place of Presentation
  北海道大学　クラーク会館、学術交流会館（北海道）
- Data Source
  KAKENHI-PLANNED-23112003
[Presentation] Cell polarity and cancer.
- Author(s)
  Ohno S
- Organizer
  2011 International Symposium on Infectious Disease and Signal Transduction, 2011 Taiwan-Japan Joint Symposium on Cell Signaling and Gene Regulation
- Place of Presentation
  College of Medicine, National Cheng Kung University（Tainan City, Taiwan）
- Invited
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] A new microtubule binding protein, p250, regulates the directional migration of epithelial cells.
- Author(s)
  佐藤由典, 秋津真志, 林健二, 天野芳子, 林郁子, 大野茂男, 鈴木厚
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Data Source
  KAKENHI-PLANNED-23112003
[Presentation] Molecular mechanisms regulating the turnover of nephrin; the role of cell polarity regulator, aPKC.
- Author(s)
  Satoh D, Harita Y, Daimon C, Hirose T, Kurihara H, Ohno S
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Data Source
  KAKENHI-PLANNED-23112003
[Presentation] Transcriptional Timing Determines the Stability of Interferon-beta mRNA.
- Author(s)
  Abe K, Ishigami T, Ann-Bin S, Ohno S, Umemura S, Yamashita A
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡（福岡県）
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] Cell polarity and the maintenance and disruption of epithelial tissues.
- Author(s)
  Ohno S
- Organizer
  US-Japan Summer Conference on Cancer, Diabetes and Inflammation
- Place of Presentation
  Beckman Center Lecture Hall（Duarte, CA, USA）
- Invited
- Data Source
  KAKENHI-PLANNED-23112003
[Presentation] PAR3 is required for restricting symmetric proliferative divisions in mouse neutral precursor cells.
- Author(s)
  Hirose T, Sugitani Y, Kusaka C, Noda T, Ohno S
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] An Apicobasal Cell Polarity Protein aPKCλ regulates the hair follicle cycling and Hair Follicle Stem Cells Homeostasis
- Author(s)
  Osada S，Minematsu N，Oda F，Akimoto K，Kawana S and Ohno S
- Organizer
  The 44th Annual European Society for Dermatological Research Meeting
- Place of Presentation
  Copenhagen, Denmark
- Year and Date
  2014-09-10 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-24591669
[Presentation] Maintenance of Dendritic Spine Morphology by PAR1b through Regulation of Microtubule Growth.
- Author(s)
  Hayashi K, Suzuki A, Hoogenraad C. C, Ohno S
- Organizer
  2011 The American Society for Cell Biology Annual Meeting
- Place of Presentation
  Colorado Convention Center(Denver, Colorado, USA)
- Data Source
  KAKENHI-PLANNED-23112003
[Presentation] Molecular mechanisms regulating the turnover of nephrin; the role of cell polarity regulator, aPKC.
- Author(s)
  Satoh D, Harita Y, Daimon C, Hirose T, Kurihara H, Ohno S
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] 細胞極性化の原理と生理機能.
- Author(s)
  大野茂男
- Organizer
  第117回解剖学会総会・全国学術集会
- Place of Presentation
  山梨大学甲府キャンパス（山梨県）
- Invited
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] Maintenance of Dendritic Spine Morphology by PAR1b through Regulation of Microtubule Dynamics.
- Author(s)
  林健二, 鈴木厚, 平井秀一, 栗原靖之, Casper C Hoogenraad, 大野茂男
- Organizer
  第63回日本細胞生物学会大会
- Place of Presentation
  北海道大学　クラーク会館、学術交流会館(北海道)
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] 限外濾過膜としてのスリット膜のターンオーバーとそのメカニズム.
- Author(s)
  佐藤大輔, 張田豊, 大門主税, 栗原秀剛, 廣瀬智威, 大野茂男
- Organizer
  第100回東京腎生理集談会
- Place of Presentation
  第100回東京腎生理集談会（東京都）
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] Epithelial cell polarity and the PAR-aPKC complex.
- Author(s)
  Ohno S
- Organizer
  Molecular Structure and Function of the Apical Junctional Complex in Epithelia and Endothelia
- Place of Presentation
  Hyatt Regency（Merida, Mexico）
- Invited
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] PAR-3 mediates the expression of Girdin/GIV/Ccdc88a to regulate epithelial cell polarity.
- Author(s)
  Sasaki K, Kakuwa T, Koga H, Ohno S
- Organizer
  US-Japan Summer Conference on Cancer, Diabetes and Inflammation
- Place of Presentation
  Beckman Center Lecture Hall（Duarte, CA, USA）
- Data Source
  KAKENHI-PLANNED-23112003
[Presentation] The regulators and the effectors of the aPKC-PAR.
- Author(s)
  Ohno S
- Organizer
  SFB Symposium 2012 "Molecular Cell Dynamics"
- Place of Presentation
  Max Planck Institut(Munster, Germany)
- Invited
- Data Source
  KAKENHI-PLANNED-23112003
[Presentation] IL-6 遺伝子発現における mRNA 転写後制御機構の解析.
- Author(s)
  安部開人, 山下暁朗, Ann-Bin Shyu, 石上友章, 大野茂男, 梅村敏
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Data Source
  KAKENHI-PLANNED-23112003
[Presentation] aPKClambda regulates mammary luminal progenitor cell propagation and its disruption in a subpopulation of breast cancer.
- Author(s)
  Akimoto K, Nagashima Y, Ishiguro H, Zheng Y W, Osato N, Sasaki K, Kojima Y, Tamura T, Taniguchi H, Noda T, Ohno S
- Organizer
  US-Japan Summer Conference on Cancer, Diabetes and Inflammation
- Place of Presentation
  Beckman Center Lecture Hall（Duarte, CA, USA）
- Data Source
  KAKENHI-PLANNED-23112003
[Presentation] Analysis of Physiological Function of MARKAP1 in the Cerebellum.
- Author(s)
  Satake T, Hayashi K, Yamashita K, Satoh Y, Ohno S, Suzuki A
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡（福岡県）
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] Maintenance of Dendritic Spine Morphology by PAR1b through Regulation of Microtubule Dynamics.
- Author(s)
  林健二, 鈴木厚, 平井秀一, 栗原靖之, Casper C Hoogenraad, 大野茂男
- Organizer
  第63回日本細胞生物学会大会
- Place of Presentation
  北海道大学　クラーク会館、学術交流会館（北海道）
- Data Source
  KAKENHI-PLANNED-23112003
[Presentation] aPKClambda regulates mammary luminal progenitor cell propagation and its disruption in a subpopulation of breast cancer.
- Author(s)
  Akimoto K, Nagashima Y, Ishiguro H, Zheng Y W, Osato N, Sasaki K, Kojima Y, Tamura T, Taniguchi H, Noda T, Ohno S
- Organizer
  US-Japan Summer Conference on Cancer, Diabetes and Inflammation
- Place of Presentation
  Beckman Center Lecture Hall（Duarte, CA, USA）
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] 細胞極性化の原理と生理機能.
- Author(s)
  大野茂男
- Organizer
  第117回解剖学会総会・全国学術集会
- Place of Presentation
  山梨大学甲府キャンパス（山梨県）
- Invited
- Data Source
  KAKENHI-PLANNED-23112003
[Presentation] A Novel Microtubule Binding Protein, MARKAP, plays essential roles for the Golgi-Ribbon Formation by Regulating Golgi-Nucleated Microtubules.
- Author(s)
  Satoh Y, Hayashi K, Amano Y, Maki T, Hayashi I, Ohno S, Suzuki A
- Organizer
  Joint Meeting of The 45th Annual Meeting of the Japanese Society of Developmental Biologists & The 64th Annual Meeting of the Japan Society for Cell Biology
- Place of Presentation
  Kobe International Conference Center.The Kobe Chamber of Commerce and Industry(兵庫県）
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] JNK Facilitates the Formation of Epithelial Cell Sheet.
- Author(s)
  Furukawa K, Ohno S, Hirai S-I
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡（福岡県）
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] A Cell Polarity Protein，aPKCλ，is Essential for Maintaining Hair Follicle Stem Cell Quiescence and Hair Follicle Regeneration
- Author(s)
  長田真一，峰松直子，小田文乃，秋本和憲，川名誠司，大野茂男
- Organizer
  第39回日本研究皮膚科学会年次学術大会
- Place of Presentation
  大阪
- Year and Date
  2014-12-12 – 2014-12-14
- Data Source
  KAKENHI-PROJECT-24591669
[Presentation] ガン抑制遺伝子Lglは、VprBPと結合することによって、単層の上皮構造を維持している.
- Author(s)
  山下和成, 井出真理子, 村松玲子, 鈴木厚, 平野久, 大野茂男
- Organizer
  第63回日本細胞生物学会大会
- Place of Presentation
  北海道大学　クラーク会館、学術交流会館(北海道)
- Data Source
  KAKENHI-PROJECT-22247030

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149. HARITA Yutaka

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
150. 石上友章

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
151. 荒川憲昭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
152. 臼杵扶佐子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
153. 石黒斉

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
154. 細野邦広

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
155. 山中智行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
156. 貫名信行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
157. 青木一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
158. 梁明秀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
159. 佐々木洋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
160. 平手良和

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
161. 足立誠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
162. 稲山嘉明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
163. 伯野史彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
164. 栗原秀剛

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ohno Shigeo 大野 茂男

HIROSE Tomonori 廣瀬 智威

OHNO Shigeo 大野 茂男

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Regulation of cell polarity and cell fates in tissue stem/progenitor cellsPrincipal Investigator

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Nephrin cycle : Analyses of the dynamic state of the podocyte slit diaphragm proteins in vivo and in vitroPrincipal Investigator

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Molecular mechanisms of the polarity-regulating signalingPrincipal Investigator

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Cell Polarity Signaling and CancerPrincipal Investigator

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Molecular mechanism of mammalian mRNA surveillancePrincipal Investigator

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ナンセンスmRNA分解系の特異的な抑制による変異遺伝子機能回復の可能性の検討Principal Investigator

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Molecular mechanism of mammalian mRNA surveillancePrincipal Investigator

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ナンセンスmRNA分解系の特異的な抑制による変異遺伝子機能回復の可能性の検討Principal Investigator

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Molecular mechanism of mammalian mRNA surveillancePrincipal Investigator

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Ohno Shigeo 大野茂男

HIROSE Tomonori 廣瀬智威

OHNO Shigeo 大野茂男