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INAGAKI Fuyuhiko  稲垣 冬彦

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Researcher Number 70011757
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Affiliation (based on the past Project Information) *help 2018: 公益財団法人微生物化学研究会, 微生物化学研究所, 客員研究員
2011 – 2018: 北海道大学, 先端生命科学研究科(研究院), 特任教授
2016: 公益財団法人微生物化学研究会, 微生物化学研究所, 客員研究員
2014: 北海道大学, 先端生命科学研究科(研究院), 教授
2013 – 2014: 北海道大学, 先端生命科学研究科(研究院), その他 … More
2013: 北海道大学, 先端生命科学研究科, 教授
2010 – 2011: 北海道大学, 大学院・先端生命科学研究院, 特任教授
2006 – 2009: 北海道大学, 大学院・薬学研究院, 教授
2007: Hokkaido University, 大学院・薬学研究科, 教授
1999 – 2005: Grad. School of Pharm., Hokkaido Univ., Prof., 大学院・薬学研究科, 教授
1998: Tokyo Metropolitan Institute of Medical Science, Researcher, 生理活性物質研究部門, 部長
1998: 財団法人東京都臨床医学総合研究所, 生理活性物質研究部門, 研究員
1997 – 1998: (財)東京都臨床医学総合研究所, 生理活性物質研究部門, 研究員
1995 – 1997: (財)東京都臨床医学総合研究所, 生理活性物質研究部, 部長
1996: 東京臨床医学総合研究所, 生理活性物質研究部門, 部長
1996: 財団法人 東京都臨床医学総合研究所, 生理活性物質研究部門, 研究員
1994 – 1995: (財)東京都臨床医学総合研究所, 生理活性物質研究部門, 部長
1994 – 1995: Tokyo Metropolitan Institute of Medical Science Researcher, 生理活性物質研究部門, 研究員
1993 – 1994: (財)東京都臨床医学総合研究所, 部長
1993: 東京都臨床医学総合研究所, 生理活性物質研究部門, 部長
1993: 財団法人 東京都臨床医学総合研究所, 生理活性物質研究部門, 研究員
1989 – 1992: 東京都臨床医学総合研究所, 室長
1991: (財)東京都臨床医学総合研究所, 生理活性物質研究部, 研究員
1991: The Tokyo Metropolitan Institute of Medical Science, 生理活性物質研究部門, 研究員
1990: (財)東京都臨床医学総合研究所, 生理活性物質研究部門, 室長
1988: Tokyo Metropolitan Institute of Medical Science, Section Chief, 生理活性物質研究部門
1987: (財)東京都臨床医学総合研究所, 生理活性物質研究部門, 室長 Less
Review Section/Research Field
Principal Investigator
Structural biochemistry / Biological Sciences / 物質生物化学 / Biological pharmacy
Except Principal Investigator
Complex systems / Biological Sciences / 物質生物化学
Keywords
Principal Investigator
NMR / SH3 / Grb2 / SH2 / N-WASP / 好中球活性酸素発生系 / Vav / デストリン / 立体構造 / SH3ドメイン … More / SH3 domain / Ash / フィロポディア / 二成分系 / リン酸基転移反応 / 嫌気センサー / TPR motif / Rac / X線結晶構造解析 / 蛋白質間相互作用 / 新規NMR技術 / protein-protein interaction / コフィリン / スペクトル解析システム / 多元的情報伝達 / 細胞質内シグナル / 核内シグナル / モエシン / 低分子量G蛋白 / コアクチベータ / CBP / 自然免疫 / NADPH酸化酵素 / PXドメイン / インターフェロン産生系 / TLR / TIR / IRF-3 / リン酸化 / Βgrp / β1-3グルカン / インターフェロン / 活性制御 / RLR / βGRP / TIRドメイン / TICAM1 / TRIF / TRAM / 細胞質因子 / p40 / ファゴソーム / PI(3)P / RIGI / CARDドメイン / ウイルス感染 / RIG-1 / MDA-5 / LGP2 / RNA結合ループ / dsRNA / 5'ppp-ssRNA / 二重連鎖DNA / チロシンキナーゼ / 過度的複合体 / 同位体ラベル / ナノディスク / 過渡的複合体 / ドッキング計算 / 架橋実験 / Cb1-b / E3リガーゼ / 自己免疫疾患 / ガン化 / RING / チロシンリン酸化 / ユビキチン化 / PI / エフェクタータンパク質 / FYVEドメイン / PH / PX / 生理活性ペプチド / 全重水素化リン脂質ミセル / ディスタンスジオメトリ- / 膜融合性ペプチド / 構造ー機能相関 / Bioactive peptides / Perdeuterated micelles / Distance geometry / EGFレセプター / シグナル伝達 / Sosペフチド / EGF / Sosペプチド / distance geometry / solution structure / erabutoxin b / heregulin alpha / IGF-II / proline-rich peptide / Shc / Sos / ミッドカイン / Link / GRB2 / 神経突起伸長 / ArcB / Tob / リン酸化チロシン / プロリンに富むペプチド / 溶液構造 / Ras / ポリプロリンヘリックス / Solution Structure / three dimensional structure of protein / X-ray crystallography / destrin / midkine / ドメイン工学 / 蛋白質スプライシング反応 / p67^<phox> / p47^<phox> / 緩和時間 / リンカー / フレキシビリティー / シス-トランス異性 / X線小角散乱 / 動的構造 / Grb2 domain engineering / Neutrophil / P67ィイD1phoxィエD1 / P47ィイD1phoxィエD1 / 情報伝達 / 細胞質内シグナル伝達 / 核内シグナル伝達 / 班会議 / シンポジウム / ワークショップ / 備品整備 / 班研究会 / signal transduction / intracellular signal transduction / nuclear signal transduction / novel NMR techniques / PRR領域 / 蛋白質立体構造 / radixin / IP3 / PTB様ドメイン / Vav-nSH3 / PRR / Grb2-cSH3 / バキュロウィルス / 多核体病ウィルス / Rho / タイトジャンクション / 好中級活性酸素発生系 / PBI / PB2 / Neurop / praline rich region / tertiary structure IP3 / 活性化機構 / 自己阻害 / p47タンデムSH3 / PRRペプチド / phagocyte oxidation system / activation mechanism / auto inhibition / p47 tandem SH3 domains / PRR peptide / αーブンガロトキシン / 単クローン抗体 / ハイブリドーマ / 無血清培地化 / 全重水素ラベル / Fab / エピトープ / α-ブンガロトキシン / ヘビ神経毒タンパク / 核磁気共鳴 / alpha-Bungarotoxin / Monoclonal antibody / hybridoma / Fab fragment / epitope Deuterium labell … More
Except Principal Investigator
NMR / 化学合成 / 蛋白質 / シグナル伝達 / 構造生物学 / シアル酸 / プロテオグリカン / 高次構造 / 転写因子 / 相互作用 / 核磁気共鳴法 / タンパク質 / 電子顕微鏡 / ガングリオシドGD_3 / ガングリオシドGQ_<1b> / セレブロシド / シアリルトランスフェラ-ゼ / 光アフィニティラベル法 / ノイラミニダ-ゼ / GQ1b / KDN / 光アフィニティ-ラベル法 / GM1 / ガングリオシド / 酵素合成 / GD_3 / N-アセチルラクトサミン型糖脂質 / sLe^xガングリオシド類縁体 / シンビオラシド / コンフォメーション / aFGF / ヘパリン / セレクチン / LTA / ビオチン化プローブ / ヒアルロニダーゼ / LIF / GAG / シアロ複合糖質 / リポタイコ酸 / 光アフィニティープローブ / ピューロマイシン / コンドロイチン硫酸 / ユビキチン / リピドA / リガンド / グアニジドガラクトース / セラミド / X線 / DNA / 領域とりまとめ / X線結晶構造解析 / 一分子計測学 / ケミカルバイオロジー / X線結晶構造解析 / ケミカル・バイオロジ / ケミカルバイオロジ / 生化学 / 細胞生物学 / 分子生物学 / 生物物理学 / X線結晶学 / 複合体 / 糖タンパク質 / 糖脂質 / レクチン / 糖転移酸素 / 糖鎖構造 / 糖鎖認識抗体 / 糖転移酵素 / エンドグリコシダ-ゼ / モノクロ-ン抗体 / エリスロポエチン / Glycoprotein / Glycolipid / Proteoglycan / Glycan structure / Glycosyltransferase / Lectin / Glycan synthesis / Monoclonal antibody / X線結晶 / 分子認識 / Structural Biology / X-ray Crystallography / Signal Transduction / Transcription / DNA-binding Proteins / RNA-binding Proteins / Molecular Biology / 国際共同研究 / 海外派遣 / 海外研究者受入 / 海外講演者招聘 / 海外研究者招聘 / 海外共同研究者受入 / タンパク質結晶 / 動的構造 / 結晶コンタクト / 融合タンパク質 / MBP / Tom20 / Tim21 / X線結晶解析 / X線小角散乱 / X線結晶解析 / 高速AFM / シグナル配列 / X線小角散乱 / 電子顕微鏡単粒子解析 / 高速AFM / オリゴ糖転移酵素 / ミトコンドリア Less
  • Research Projects

    (24 results)
  • Research Products

    (58 results)
  • Co-Researchers

    (73 People)
  •  Support activities aimed at international network formation in the research area of dynamic structural life sciences

    • Principal Investigator
      Kohda Daisuke
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      Kyushu University
  •  Rational design of crystal contact-free space in protein crystals for analyzing spatial distribution of motions within protein molecules

    • Principal Investigator
      Kohda Daisuke
    • Project Period (FY)
      2014 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      Kyushu University
  •  Structural basis of cell-signaling complexes mediating signal perception, transduction and responses.

    • Principal Investigator
      HAKOSHIMA Toshio
    • Project Period (FY)
      2010 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Nara Institute of Science and Technology
  •  Structural analysis of CBL protein complexes as a signal suppressorPrincipal Investigator

    • Principal Investigator
      INAGAKI Fuyuhiko
    • Project Period (FY)
      2010 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Hokkaido University
  •  Integrative understanding of biological processes mediated by transient macromolecul ar complexes; New technology for visualizing physiologically metastable states

    • Principal Investigator
      SHIMADA Ichio
    • Project Period (FY)
      2009 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      The University of Tokyo
  •  RIG-I、MDA-5からIRF-3に至るシグナル伝達の構造生物学Principal Investigator

    • Principal Investigator
      稲垣 冬彦
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Hokkaido University
  •  Structural Biology of Innate ImmunityPrincipal Investigator

    • Principal Investigator
      INAGAKI Fuyuhiko
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Biological pharmacy
    • Research Institution
      Hokkaido University
  •  Structural Biology of Phagocyte oxidationPrincipal Investigator

    • Principal Investigator
      INAGAKI Fuyuhiko
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Structural biochemistry
    • Research Institution
      Hokkaido University
  •  Protein-protein interaction in intracellular signal transductionPrincipal Investigator

    • Principal Investigator
      INAGAKI Fuyuhiko
    • Project Period (FY)
      1998 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Biological Sciences
    • Research Institution
      HOKKAIDO UNIVERSITY
      Tokyo Metropolitan Organization for Medical Research
  •  Protein-protein interaction in intracellular signal transductionPrincipal Investigator

    • Principal Investigator
      INAGAKI Fuyuhiko
    • Project Period (FY)
      1998 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Biological Sciences
    • Research Institution
      Hokkaido University
      Tokyo Metropolitan Organization for Medical Research
  •  構造生物学にもとづくシグナル伝達機構の解明Principal Investigator

    • Principal Investigator
      稲垣 冬彦
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Structural biochemistry
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  Structural studies on signal transduction related to Ash/Grb2Principal Investigator

    • Principal Investigator
      INAGAKI Fuyuhiko
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Structural biochemistry
    • Research Institution
      HOKKAIDO UNIVERSITY
      Tokyo Metropolitan Organization for Medical Research
  •  糖鎖及び糖鎖複合体の解析・分子設計及び再構成

    • Principal Investigator
      小川 智也
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  Analyses of Signal Transduction Mechanisms based on Protein Structures

    • Principal Investigator
      NISHIMURA Yoshifumi
    • Project Period (FY)
      1994 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Yokohama City University
  •  Role of three dimensional structure of proteins in signal transductionPrincipal Investigator

    • Principal Investigator
      INAGAKI Fuyuhiko
    • Project Period (FY)
      1994 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  NMRによるコフィリン、デストリンの立体構造解析と機能相関Principal Investigator

    • Principal Investigator
      稲垣 冬彦
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  蛋白質の高次構造に基づくシグナル認識機構の解明

    • Principal Investigator
      NISHIMURA Yoshifumi
    • Project Period (FY)
      1993
    • Research Institution
      Yokohama City University
  •  Elucidation of Molecular Mechanism of Signal Transduction Mediated by Growth Factor-Receptor SystemPrincipal Investigator

    • Principal Investigator
      INAGAKI Fuyuhiko
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Structural biochemistry
    • Research Institution
      Tokyo Metropolitan Institute of Medical Science
  •  ガングリオシドの化学合成

    • Principal Investigator
      芝 哲夫
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Protein Research Foundation
  •  ガングリオシド糖鎖の化学合成

    • Principal Investigator
      芝 哲夫
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Protein Research Foundation
  •  ガングリオシド糖鎖の化学合成

    • Principal Investigator
      芝 哲夫
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Protein Research Foundation
  •  Structure -Function relationship of Membrane Bound Peptides Using DPC MicellesPrincipal Investigator

    • Principal Investigator
      INAGAKI Fuyuhiko
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      物質生物化学
    • Research Institution
      The Tokyo Metropolitan Institute of Medical Science
  •  Studies on Glycobilogy

    • Principal Investigator
      KAWASAKI Toshisuke, 木幡 陽
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      物質生物化学
    • Research Institution
      Kyoto University
      The University of Tokyo
  •  Molecular Recognition of Antigen Determinant by Monoclonal Antibody Specific to Neurotoxins from Snake VenomsPrincipal Investigator

    • Principal Investigator
      INAGAKI Fuyuhiko
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      物質生物化学
    • Research Institution
      Tokyo Metropolitan Institute of Medical Science

All 2014 2013 2012 2011 2010 2009 2008 2007 2006 2003 2002 Other

All Journal Article Presentation Patent

  • [Journal Article] The N-terminal domain of TIR domain-containing adaptor molecule-1, TICAM-1.2014

    • Author(s)
      Kumeta H, Sakakibara H, Enokizono Y, Ogura K, Horiuchi M, Matsumoto M, Seya T, Inagaki F.
    • Journal Title

      J. Biomolec. NMR

      Volume: 58(3) Pages: 227-230

    • DOI

      10.1007/s10858-014-9819-1

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22121008, KAKENHI-PROJECT-23590558, KAKENHI-PROJECT-24560954
  • [Journal Article] Structural basis of starvation-induced assembly of the autophagy intiation complex2014

    • Author(s)
      Yuko Fujioka, Sho W Suzuki, Hayashi Yamamoto, Chika Kondo-Kakuta, Yayoi Kimura, Hisashi Hirano, Rinji Akada, Fuyuhiko Inagaki, Yoshinori Ohsumi, Nobuo N Noda
    • Journal Title

      Nature Structural & Molcular Biology

      Volume: 21(発表確定) Pages: 513-21

    • DOI

      10.1038/nsmb.2822

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-12J08262, KAKENHI-PROJECT-12J40279, KAKENHI-PLANNED-22121008, KAKENHI-PROJECT-23000015, KAKENHI-PROJECT-24770182, KAKENHI-PLANNED-25111004, KAKENHI-PUBLICLY-26111508, KAKENHI-PROJECT-26870828
  • [Journal Article] Practical applications of hydrostatic pressure to refold proteins from inclusion bodies for NMR structural studies2013

    • Author(s)
      Ogura K., Kobashigawa Y., Saio T., Kumeta H., Torikai S., Inagaki F.
    • Journal Title

      Protein Engineering, Design and Selection

      Volume: 26(6) Pages: 409-16

    • DOI

      10.1093/protein/gzt012

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22121008, KAKENHI-PROJECT-22570109, KAKENHI-PUBLICLY-24121701
  • [Journal Article] Structures and interface mapping of the TIR domain-containing adaptor molecules involved in interferon signaling.2013

    • Author(s)
      Enokizono Y, Kumeta H, Funami K, Horiuchi M, Sarmiento J, Yamashita K, Standley DM, Matsumoto M, Seya T, Inagaki F.
    • Journal Title

      Proc. Natl. Acad. Sci. U. S. A.

      Volume: 110(49) Pages: 19908-13

    • DOI

      10.1073/pnas.1222811110

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22114008, KAKENHI-PLANNED-22121008, KAKENHI-PROJECT-23390120, KAKENHI-PROJECT-23590558, KAKENHI-PROJECT-24560954, KAKENHI-PROJECT-24659214
  • [Journal Article] High-Throughput Evaluation Method for Drug Association with Pregnane X Receptor (PXR) Using Differential Scanning Fluorometry.2013

    • Author(s)
      Sekiguchi M., Kobashigawa Y., Moriguchi H., Kawasaki M., Yuda M, Teramura T., Inagaki F.
    • Journal Title

      J Biomol Screen

      Volume: 18(9) Pages: 1084-91

    • DOI

      10.1177/1087057113491826

    • Data Source
      KAKENHI-PLANNED-22121008
  • [Journal Article] The Domain Organization of p67phox, a Protein Required for Activation of the Superoxide-Producing NADPH Oxidase in Phagocytes.2009

    • Author(s)
      Yuzawa S., Miyano K., Honbou K., Inagaki F., Sumimoto H.
    • Journal Title

      J Innate Immun. 1

      Pages: 543-555

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109002
  • [Journal Article] Solution structure of the silkworm βGRP/GNBP3 N-terminal domain reveals the mechanism for β-1, 3-glucan-specific recognition.2009

    • Author(s)
      Takahasi K., Ochiai M., Horiuchi M., Kumeta H., Ogura K., Ashida M., Inagaki F.
    • Journal Title

      Proc Natl Acad Sci U S A 106

      Pages: 11679-11684

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109002
  • [Journal Article] 細胞内シグナル伝達2008

    • Author(s)
      稲垣冬彦
    • Journal Title

      蛋白質核酸酵素 53

      Pages: 600-603

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109002
  • [Journal Article] Nonself RNA-Sensing Mechanism of RIG-I Helicase and Activation of Antiviral Immune Responses.2008

    • Author(s)
      Takahasi K., Yoneyama M., Nishihori T., Hirai R., Kumeta H., Narita R., Gale M. Jr, Inagaki F, Fujita T.
    • Journal Title

      Mol. Cell 29

      Pages: 428-440

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109002
  • [Journal Article] 極性発現に必要なPB1ドメイン間の相互作用2008

    • Author(s)
      稲垣冬彦
    • Journal Title

      生体の科学 58

      Pages: 402-403

    • Data Source
      KAKENHI-PROJECT-17109002
  • [Journal Article] 細胞内シグナル伝達2008

    • Author(s)
      稲垣冬彦
    • Journal Title

      蛋白質核酸酵素 53(Invited)

      Pages: 600-603

    • Data Source
      KAKENHI-PROJECT-19041003
  • [Journal Article] 極性発現に必要なPB1ドメイン間の相互作用2007

    • Author(s)
      稲垣冬彦
    • Journal Title

      生体の科学 58

      Pages: 402-403

    • Data Source
      KAKENHI-PROJECT-19041003
  • [Journal Article] Full-length p40phox structure suggests a basis for regulation mechanism of its membrane binding.2007

    • Author(s)
      Honbou K., Minakami R., Yuzawa S., Takeya R., Suzuki N.N., Kamakura S., Sumimoto H., Inagaki F.
    • Journal Title

      EMBO J 26

      Pages: 1176-1186

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109002
  • [Journal Article] Grb2 SH2の構造を基盤とした抗ガン剤の設計2007

    • Author(s)
      稲垣冬彦
    • Journal Title

      医薬ジャーナル 43

      Pages: 5-10

    • Data Source
      KAKENHI-PROJECT-17109002
  • [Journal Article] Grb2 SH2の構造を基盤とした抗ガン剤の設計2007

    • Author(s)
      稲垣冬彦
    • Journal Title

      医薬ジャーナル 43

      Pages: 5-10

    • Data Source
      KAKENHI-PROJECT-19041003
  • [Journal Article] Activation of the superoxide-producing phagocyte NADPH oxidase requires co-operation between the tandem SH3 domains of p47phox in recognition of a polyproline type II helix and an adjacent alpha-helix of p22phox.2006

    • Author(s)
      Nobuhisa I., Takeya R., Ogura K., Ueno N., Kohda D., Inagaki F. Sumimoto H.
    • Journal Title

      Biochem. J 396

      Pages: 183-192

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109002
  • [Journal Article] NMR Solution Structure of the Tandem Src Homology 3 Domains p47phox Complexed with a p22phox-derived Proline-rich Peptide.2006

    • Author(s)
      Ogura K., Nobuhisa I., Yuzawa S., Takeya R., Torikai S., Saikawa K., Sumimoto H., Inagaki F.
    • Journal Title

      J. Biol. Chem 281

      Pages: 3660-3668

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17109002
  • [Journal Article] SH3相互の新規認識2003

    • Author(s)
      稲垣冬彦
    • Journal Title

      Medical Science Digest 29,2

      Pages: 30-33

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14208076
  • [Journal Article] Grb2を介するシグナル伝達の構造生物学2002

    • Author(s)
      稲垣冬彦
    • Journal Title

      生化学 74

      Pages: 1229-1236

    • NAID

      10010298445

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14208076
  • [Journal Article] Solution structures of cytosolic RNA sensor MDA5 and LGP2 C-terminal domains: identification of the RNA recognition loop in RIG-I-like receptors.

    • Author(s)
      Takahasi K., Kumeta H., Tsuduki N., Narita R., Shigemoto T., Hirai R., Yoneyama M., Horiuchi M., Ogura K., Fujita T., Inagaki F.
    • Journal Title

      J Biol Chem

      Pages: 17465-17474

    • NAID

      120001415118

    • Data Source
      KAKENHI-PROJECT-17109002
  • [Patent] リン酸化タンパク質の製法2006

    • Inventor(s)
      小橋川敬博, 内藤雅人, 稲垣冬彦
    • Industrial Property Rights Holder
      北海道大学
    • Industrial Property Number
      2005-359966
    • Filing Date
      2006-02-21
    • Data Source
      KAKENHI-PROJECT-17109002
  • [Patent] シグナル伝達活性を有する細胞質蛋白質の活性制御方法2003

    • Inventor(s)
      稲垣 冬彦, 橋田 修吉
    • Industrial Property Rights Holder
      北海道大学
    • Industrial Property Number
      2003-409281
    • Filing Date
      2003-12-08
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14208076
  • [Patent] NADPHオキシダーゼ活性を阻害するポリペプチド2003

    • Inventor(s)
      稲垣 冬彦, 橋田 修吉
    • Industrial Property Rights Holder
      北海道大学
    • Industrial Property Number
      2003-409282
    • Filing Date
      2003-12-08
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14208076
  • [Presentation] Paramagnetic lanthanide probe visualizes change of domain orientation induced by substrate and inhibitor binding and is a useful tool for drug screening.2014

    • Author(s)
      稲垣 冬彦
    • Organizer
      第5回日台NMRシンポジウム
    • Place of Presentation
      北海道大学百年記念会館(北海道札幌市)
    • Year and Date
      2014-09-29
    • Data Source
      KAKENHI-PLANNED-22121008
  • [Presentation] 常磁性イオンを利用した長距離情報の取得/Acquirement of long distance information using paramagnetic ion.2014

    • Author(s)
      稲垣 冬彦
    • Organizer
      第14回日本蛋白質科学会年会
    • Place of Presentation
      ワークピア横浜/横浜産貿ホール マリネリア(神奈川県横浜市)
    • Year and Date
      2014-06-27
    • Data Source
      KAKENHI-PLANNED-22121008
  • [Presentation] Ligand-driven conformational changes of MurD characterized by paramagnetic NMR.2013

    • Author(s)
      稲垣 冬彦
    • Organizer
      第52回 NMR 討論会
    • Place of Presentation
      石川県立音楽堂(石川県金沢市)
    • Data Source
      KAKENHI-PLANNED-22121008
  • [Presentation] Ligand-driven conformational changes of MurD characterized by paramagnetic NMR2013

    • Author(s)
      稲垣 冬彦
    • Organizer
      APNMR5(5th Asia-Pacific NMR Symposium in conjunction with ANZMAG 2013)
    • Place of Presentation
      Brisbane Convention and Exhibition Centre, Australia
    • Data Source
      KAKENHI-PLANNED-22121008
  • [Presentation] 金属イオンを利用した古くて新しい常磁性 NMR 解析2013

    • Author(s)
      稲垣 冬彦
    • Organizer
      第36回日本分子生物学会年会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Invited
    • Data Source
      KAKENHI-PLANNED-22121008
  • [Presentation] NMR-based drug discovery utilizing paramagnetic lanthanide probe2012

    • Author(s)
      Fuyuhiko INAGAKI
    • Organizer
      International Conference on Magnetic Resonance in Biological Systems2012
    • Place of Presentation
      Lyon Convention Centre (フランス)
    • Year and Date
      2012-08-19
    • Invited
    • Data Source
      KAKENHI-PLANNED-22121008
  • [Presentation] シグナル抑制因子CBLの分子複合体構造と病因変異の解析2012

    • Author(s)
      稲垣冬彦
    • Organizer
      新学術領域研究「構造細胞生物学」 平成24年度全体会議・総括班会議
    • Place of Presentation
      湯本富士屋ホテル(神奈川県)
    • Year and Date
      2012-06-13
    • Data Source
      KAKENHI-PLANNED-22121008
  • [Presentation] Structural Biology of Innate Immunity2012

    • Author(s)
      Fuyuhiko INAGAKI
    • Organizer
      Towards Comprehensive Understandingf of Immune Dynamism2012
    • Place of Presentation
      Osaka University(吹田市)
    • Year and Date
      2012-10-29
    • Invited
    • Data Source
      KAKENHI-PLANNED-22121008
  • [Presentation] Phosphorylation induced conformation change and its biological implication2011

    • Author(s)
      稲垣冬彦
    • Organizer
      第49回日本生物物理学会年会
    • Place of Presentation
      兵庫県立大学姫路書写キャンパス(姫路)(招待講演)
    • Data Source
      KAKENHI-PLANNED-22121008
  • [Presentation] シグナル抑制因子CBLの分子複合体構造と病因変異の解析2011

    • Author(s)
      稲垣冬彦
    • Organizer
      第2回全体会議新学術領域研究「構造細胞生物学」
    • Place of Presentation
      ホテル日航奈良(奈良)
    • Data Source
      KAKENHI-PLANNED-22121008
  • [Presentation] 複合体構造研究の一工夫2011

    • Author(s)
      箱嶋敏雄, 稲垣冬彦
    • Organizer
      第11回蛋白質科学会年会
    • Place of Presentation
      吹田市
    • Year and Date
      2011-06-09
    • Data Source
      KAKENHI-ORGANIZER-22121001
  • [Presentation] Lanthanide probe method and its application to ligand screening2011

    • Author(s)
      Fuyuhiko Inagaki
    • Organizer
      平成23年度日本分光学会年次講演会
    • Place of Presentation
      理化学研究所横浜研究所交流棟(横浜)(招待講演)
    • Data Source
      KAKENHI-PLANNED-22121008
  • [Presentation] Application of the paframagnetic lanthanide probe using a tag : structural analysis, ligand screening, and signal assignment2011

    • Author(s)
      Fuyuhiko Inagaki
    • Organizer
      ISNMR2011
    • Place of Presentation
      大さん橋ホール(横浜)
    • Data Source
      KAKENHI-PLANNED-22121008
  • [Presentation] Development and application of NMR tools useful for structural cell biology2011

    • Author(s)
      稲垣冬彦
    • Organizer
      第11回日本蛋白質科学会年会
    • Place of Presentation
      ホテル阪急エキスポパーク(大阪)(招待講演)
    • Data Source
      KAKENHI-PLANNED-22121008
  • [Presentation] Structural and Functional Studies of Proteins by NMR2011

    • Author(s)
      稲垣冬彦
    • Organizer
      プロテイン・アイランド・松山国際シンポジウム2011
    • Place of Presentation
      松山全日空ホテル(松山)(招待講演)
    • Data Source
      KAKENHI-PLANNED-22121008
  • [Presentation] NMR studies of molecular interaction using PCS and anodisc.2010

    • Author(s)
      Fuyuhiko Inagaki
    • Organizer
      2010 International Chemical Congress of Pacific Basin Societies
    • Place of Presentation
      Hawaii Convention Center (Honolulu)(招待講演)
    • Data Source
      KAKENHI-PLANNED-22121008
  • [Presentation] Soft interaction in phagocyte oxidation system2009

    • Author(s)
      稲垣冬彦
    • Organizer
      International Symposium on Molecular Soft Interactions in Biological Systems
    • Place of Presentation
      千里ライフサイエンスセンター
    • Data Source
      KAKENHI-PROJECT-17109002
  • [Presentation] Structural biology of autophagy2008

    • Author(s)
      Fuyuhiko Inagaki
    • Organizer
      The 9th RIES-Hokudai International Symposium
    • Place of Presentation
      Sapporo創造的研究イニシアティブ"sousei"
    • Data Source
      KAKENHI-PROJECT-17109002
  • [Presentation] Structural Biology of Autophagy. International Conference On Structural Genomics Organization2008

    • Author(s)
      Fuyuhiko Inagaki
    • Organizer
      International Conference On Structural Genomics Organization
    • Place of Presentation
      University of Oxford
    • Data Source
      KAKENHI-PROJECT-17109002
  • [Presentation] Structural basis for the transforming activity of human-cancer related signaling adaptor protein CRK2008

    • Author(s)
      Fuyuhiko Inagaki
    • Organizer
      International Conference Magnetic in Biological Systems
    • Place of Presentation
      San Diego
    • Data Source
      KAKENHI-PROJECT-19041003
  • [Presentation] NMR構造生物学の新展開2008

    • Author(s)
      稲垣冬彦
    • Organizer
      平成20年度日本分光学会NMR分光部会シンポジウム
    • Place of Presentation
      東京大学薬学部講堂
    • Year and Date
      2008-09-01
    • Data Source
      KAKENHI-PROJECT-19041003
  • [Presentation] Structural Biology of Autophagy. International Conference On Structural Genomics Organization2008

    • Author(s)
      Fuyuhiko Inagaki
    • Organizer
      International Conference On Structural Genomics Organization
    • Place of Presentation
      University of Oxford
    • Data Source
      KAKENHI-PROJECT-19041003
  • [Presentation] Structural basis for the transforming activity of human-cancer related s ignaling adaptor protein CRK2008

    • Author(s)
      Fuyuhiko Inagaki
    • Organizer
      International Conference Magnetic in Biological Systems
    • Place of Presentation
      San Diego
    • Data Source
      KAKENHI-PROJECT-17109002
  • [Presentation] 常磁性ランタニドプローブ法のタンパク質構造解析への応用2008

    • Author(s)
      稲垣冬彦
    • Organizer
      BMB2008
    • Place of Presentation
      神戸ポートアイランド
    • Data Source
      KAKENHI-PROJECT-19041003
  • [Presentation] 常磁性ランタニドプローブ法のタンパク室構造解析への応用2008

    • Author(s)
      稲垣冬彦
    • Organizer
      BMB2008
    • Place of Presentation
      神戸ポートアイランド
    • Data Source
      KAKENHI-PROJECT-17109002
  • [Presentation] Solution structure of RIG-like receptor C-terminal domains2008

    • Author(s)
      Fuyuhiko Inagaki
    • Organizer
      回日本免疫学会総会・学術集会・国際シンポジウム
    • Place of Presentation
      国立京都国際会館
    • Data Source
      KAKENHI-PROJECT-19041003
  • [Presentation] Solution structure of RIG-like receptor C-terminal domains2008

    • Author(s)
      Fuyuhiko Inagaki
    • Organizer
      回日本免疫学会総会・学術集会・国際シンポジウム
    • Place of Presentation
      国立京都国際会館
    • Data Source
      KAKENHI-PROJECT-17109002
  • [Presentation] NMR構造生物学の新展開2008

    • Author(s)
      稲垣冬彦
    • Organizer
      平成20年度日本分光学会NMR分光部会シンポジウム
    • Place of Presentation
      東京大学薬学部講堂
    • Year and Date
      2008-09-01
    • Data Source
      KAKENHI-PROJECT-17109002
  • [Presentation] Structural Basis for the regulation of Phagocyte NADPH Oxidase Activity2007

    • Author(s)
      Fuyuhiko Inagaki
    • Organizer
      The 16th ISMAR conference
    • Place of Presentation
      Kenting, Taiwan
    • Data Source
      KAKENHI-PROJECT-17109002
  • [Presentation] Structural basis for the transforming activity of human cancer-related signaling adaptor protein CRK2007

    • Author(s)
      Fuyuhiko Inagaki
    • Organizer
      よこはまNMR構造生物学研究会「International Symposium on Drug Discovery and Design by NMR」
    • Place of Presentation
      横浜 理化学研究所横浜研究所 交流棟ホール
    • Year and Date
      2007-10-22
    • Data Source
      KAKENHI-PROJECT-17109002
  • [Presentation] Structural basis for superoxide generation by phagocyte NADPH oxidase2007

    • Author(s)
      Fuyuhiko Inagaki
    • Organizer
      The 2nd Asia-Pacific NMR Symposium
    • Place of Presentation
      Hsinchu, Taiwan. Lakeshore Hotel
    • Data Source
      KAKENHI-PROJECT-17109002
  • [Presentation] Structural basis for the transforming activity of human cancer-related signaling adaptor protein CRK2007

    • Author(s)
      稲垣冬彦
    • Organizer
      よこはまNMR構造生物学研究会「International Symposium on Drug Discovery and Design by NMR」
    • Place of Presentation
      横浜 理化学研究所横浜研究所交流ホール
    • Year and Date
      2007-10-22
    • Data Source
      KAKENHI-PROJECT-19041003
  • [Presentation] Structural Basis for the regulation of Phagocyte NADPH Oxidase Activity. The 16th ISMAR conference2007

    • Author(s)
      Fuyuhiko Inagaki
    • Organizer
      The 16th ISMAR conference,
    • Place of Presentation
      Taiwan Howard Beach Resort Kenting
    • Data Source
      KAKENHI-PROJECT-17109002
  • [Presentation] Structural analysis of human cancer related adaptor protein Crk and its biological implications.2007

    • Author(s)
      Fuyuhiko Inagaki
    • Organizer
      The KIAS-Soongsil Conference on Protein Structure and Function(7th Conference)
    • Place of Presentation
      Seoul, Korea. Soongsil University
    • Data Source
      KAKENHI-PROJECT-17109002
  • [Presentation] Paramagnetic lanthanide probe visualizes change of domain orientation induced by substrate and inhibitor binding and is a useful tool for drug screening.

    • Author(s)
      稲垣 冬彦
    • Organizer
      ICMRBS 2014
    • Place of Presentation
      ハイアット リージェンシー (アメリカ合衆国)
    • Year and Date
      2014-08-24 – 2014-08-29
    • Data Source
      KAKENHI-PLANNED-22121008
  • 1.  KOHDA Daisuke (80186618)
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  • 2.  SHIRAKAWA Masahiro (00202119)
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  • 48.  KYOUGOKU Yoshimasa (90012632)
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  • 49.  TSUKITA Shoichiro (50155347)
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  • 50.  KASE Ryouichi (20150203)
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  • 51.  KITAGAWA Hisayo (70124451)
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  • 52.  金岡 祐一 (50001029)
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  • 53.  隅田 泰生 (70179282)
    # of Collaborated Projects: 1 results
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  • 54.  木曽 真 (90092931)
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  • 55.  梶本 哲也 (80185777)
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  • 56.  楠本 正一 (30028253)
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  • 57.  高橋 清大 (90399965)
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  • 58.  木幡 陽 (30030852)
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  • 59.  大沢 利昭 (40012603)
    # of Collaborated Projects: 1 results
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  • 60.  伊倉 光彦 (00142688)
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  • 61.  今川 正良 (20136823)
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  • 62.  寺澤 宏明 (10300956)
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  • 63.  小椋 賢治 (14780469)
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  • 64.  安藤 敏夫 (50184320)
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  • 65.  西田 紀貴 (50456183)
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  • 66.  杉田 有治 (80311190)
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  • 67.  塚崎 智也 (80436716)
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  • 68.  TAMA FLORENCE (20648191)
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  • 69.  瀬谷 司
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  • 70.  松本 美佐子
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    # of Collaborated Products: 2 results
  • 71.  大隅 良典
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    # of Collaborated Products: 1 results
  • 72.  山本 林
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    # of Collaborated Products: 1 results
  • 73.  藤岡 優子(野田優子)
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    # of Collaborated Products: 1 results

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