KUSUMOTO Shoichi 楠本正一

… Alternative Names

楠本正一

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Researcher Number	30028253
Other IDs
Affiliation (based on the past Project Information) *help	2012: 公益財団法人サントリー生命科学財団, 生物有機科学研究所, 元所長 2012: 公益財団法人サントリー生命科学財団, 生物有機科学研究所, 所長 2009: 財)サントリー生物有機科学研究所, 所長 2007: (財)サントリー生物有機科学研究所, 所長 2002 – 2003: 大阪大学, 大学院・理学研究科, 教授 … More 1996 – 1999: 大阪大学, 大学院・理学研究科, 教授 1988 – 1995: 大阪大学, 理学部, 教授 1987: 大阪大学, 理学部, 助教授 Less
Review Section/Research Field	Principal Investigator 天然物有機化学 / Bioorganic chemistry Except Principal Investigator 天然物有機化学 / Chemistry related to living body / Living organism molecular science / Structural biochemistry / Bioorganic chemistry
Keywords	Principal Investigator リポ多糖 / 複合糖質 / 糖タンパク質 / 糖脂質 / 重水素標識 / 化学合成 / 生物活性 / 超分子 / 免疫増強活性 / 蛍光標識 … More / 天然有機化合物 / 抗腫瘍活性 / リポタイコ酸 / Immunostimulation / リピドA / グリコホリン / 糖転移酵素 / 細胞増殖 / 立体配座 / ノイラミン酸 / 精密構造認識 / イノシトールリン酸 / シアロ糖蛋白質 / 糖鎖抗原 / レセプター / 単クローン抗体 / 構造認識 / DNA / 脂質 / 糖質 / 蛋白質 / 多糖 / グルカン / デキストラン / 酵素分解 / 接続酸化 / ウロン酸 / Glnoーconjugates / lipoteichoic Acid / LipopoLy Saccharides / ヘパリン / 構造解析 / 合成 / リン酸化ペプチド / ホスホアミノ酸 / ホスホセリン / ミコバクテリア / Glycoconjugates / Lipoteichoic acid / Heparin / Structural analysis / Synthesis / Fluorescence labeling / Phosphopeptides / 内毒素 / ペプチドグリカン / ムラミルペプチド / リセプター / 自然免疫 / Lipopolysaccharide / Endotoxin / Lipid A / Peptidoglycan / Muramylpeptide / Receptor / Bioactivity / Innate immunity … More Except Principal Investigator 酵素 / 動的天然物化学 / 光学分割 / 精密構造認識 / 生体低分子 / 糖質 / 核酸 / 励起分子 / 細胞表層 / 分子認識 / 糖鎖 / 自然免疫 / 固体NMR法 / 脂質二重膜 / 糖脂質 / 1β-メチルカルバペネム / 糖鎖合成 / キラル四級中心 / ホモキラル合成 / 連続的クライゼンーエン手法 / 不斉水素移動反応 / エナンチオ選択的不斉合成 / 速度論的光学分割 / リパーゼ / 生物発光 / 生理活性化合物 / 人工細胞 / aFGF / ヘパリン / セレクチン / LTA / ビオチン化プローブ / ヒアルロニダーゼ / LIF / GAG / シアロ複合糖質 / リポタイコ酸 / 光アフィニティープローブ / ピューロマイシン / コンドロイチン硫酸 / ユビキチン / リピドA / リガンド / グアニジドガラクトース / セラミド / プロテオグリカン / 高分子 / 集合体 / 生体機能材料 / リポ多糖 / 会合状態 / 脂質ラフト / ラフト膜 / 運動性 / 顕微鏡観測 / 拡散速度 / 膜タンパク質 / 生体膜 / 膜挿入 / 構造決定 / 有機合成 / 生理活性物質 / シャペロン / 生理活性機構 / 生活性物質 / GPIアンカー / 酵母培養系 / GPIアンカー型蛋白質 / 固体ＮＭＲ / 1,3-dopolarcyclsaddition / 不斉増殖 / 不斉合成 / 細胞表層糖質 / アミローストリスフェユルカルバメート / コドン認識 / イソプレノイド / 生合成 / 光受容膜 / 超効率不斉増殖 / エメチン / 触媒的不斉合成 / シリル化反応 / ノイラミン酸 / 液体クロマトグラフィー / 神経毒 / 神経毒の単離 / 神経突起伸展作用物質 / 細胞生長制御物質 / 発癌プロモーター / 卵割阻害活性物質 / 摂食阻害物質 / 他感作用物質 / 神経毒の合成 / 発癌プロモ-タ- / 発癌性物質 / Neurotoxins / Isolation of neurotoxins / Neurotrophic compounds / Cell grouth control factors / Carcinogenic promotors / Cell decision inhibitors / Antifeedant / Allelopasic substances / テルペノイドジアルデヒド / 海産天然物 / シガテラ毒 / 捕食防御物質 / 発癌物質 / 抗腫瘍性物質 / DNA切断機構 / 複合糖質 / 海洋天然物質 / 神経興奮性物質 / ワラビ発癌物質 / DNA切断分子機構 / 抗腫瘍性天然物質 / 抗酸化性天然物質 / 膜透過 / Terpenoid Dialdehyde / Marine Natural Product / Carcinogenic Substance / DNA Cleavage Mechanism / Antitumor Compound / Defensive Substance / Glycolipid Less

Function and structure of novel glycolipid essential for membrane protein integration
- Principal Investigator
  
  SHIMAMOTO Keiko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  Suntory Foundation for Life Sciences
Interaction between Innate Immune Receptor CD14 and Ligand LPS on Membranes
- Principal Investigator
  
  三浦薫 (野村薫 / 三浦薫(野村薫))
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Suntory Foundation for Life Sciences
Interaction of Lipopolysaccharide and Phospholipid in Mixed Membrane Investigated by Solid-State NMR Spectroscopy
- Principal Investigator
  
  MIURA Kaoru
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Suntory Institute for Bioorganic Research
Chemical approach for the structure and function of key compounds in innate immunityPrincipal Investigator
- Principal Investigator
  
  KUSUMOTO Shoichi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Osaka University
糖分子鎖集合体
- Principal Investigator
  
  小林一清
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Nagoya University
糖鎖及び糖鎖複合体の解析・分子設計及び再構成
- Principal Investigator
  
  小川智也
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
糖質の関与する超分子形成と機能Principal Investigator
- Principal Investigator
  
  楠本正一
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
天然超分子化学の総合的研究Principal Investigator
- Principal Investigator
  
  楠本正一
- Project Period (FY)
  1994 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
動的天然物化学の総合的研究
- Principal Investigator
  
  小倉協三
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
天然超分子の化学的研究Principal Investigator
- Principal Investigator
  
  楠本正一
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Institution
  Osaka University
COMPREHENSIVE RESEARCH TOWARD THE ELUCIDATION OF BIOLOGICAL ACTIVITIES OF NATURAL ORGANIC COMPOUNDS
- Principal Investigator
  
  ISOE Sachihiko
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  OSAKA CITY UNIVERSITY
Structural and Synthetic studies of biologically active natural glycoconjugates and peptidesPrincipal Investigator
- Principal Investigator
  
  KUSUMOTO Shoichi
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Osaka University
動的天然物化学の総合的研究
- Principal Investigator
  
  小倉協三
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
糖質の精密構造認識と機能発現Principal Investigator
- Principal Investigator
  
  楠本正一
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
ORGANIC CHEMISTRY OF THE BIOSYSTEM CONTROL SUBSTANCES
- Principal Investigator
  
  SHIRAHAMA Haruhisa
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  天然物有機化学
- Research Institution
  HOKKAIDO UNIVERSITY,(FACULTY OF SCIENCE)
動的天然物化学の総合的研究
- Principal Investigator
  
  小倉協三
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
糖質の精密構造認識と機能発現Principal Investigator
- Principal Investigator
  
  楠本正一
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
糖質の精密構造認識と機能発現Principal Investigator
- Principal Investigator
  
  楠本正一
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
不斉分子識別に基づく分子変換
- Principal Investigator
  
  福本圭一郎
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
Chemical Study on Immunostimulating Natural GlycoconjugatesPrincipal Investigator
- Principal Investigator
  
  KUSUMOTO Shoichi
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  天然物有機化学
- Research Institution
  Osaka University
分子認識を目指す動的天然物化学
- Principal Investigator
  
  後藤俊夫
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  天然物有機化学
- Research Institution
  Nagoya University
不斉分子識別に基づく分子変換
- Principal Investigator
  
  福本圭一郎
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
米糖から得られる抗腫瘍活性多糖の化学的研究Principal Investigator
- Principal Investigator
  
  楠本正一
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  天然物有機化学
- Research Institution
  Osaka University
不斉分子識別に基づく分子変換
- Principal Investigator
  
  福本圭一郎
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University

All 2012 2011 2010 2008 Other

All Journal Article Presentation Book Patent

[Book] "Lipopolysaccharide Induces Raft Domain Expansion in a Cholesterol-ContainingMembrane"in "Advances in Biological Solid-State NMR: Proteins and Membrane-Active Peptides"
- Author(s)
  K. Nomura and S. Kusumoto
- Publisher
  RSC Publishing,
- Data Source
  KAKENHI-PROJECT-22570127
[Journal Article] MPIase is a glycolipozyme essential for membrane protein integratio2012
- Author(s)
  Nishiyama, K., Maeda,M., Yanagisawa,K., Nagase, R., Komura, H., Iwashita, T., Yamagaki, T., Kusumoto, S., Tokuda, H., Shimamoto, K.
- Journal Title
  
  Nat Commun
  
  Volume: 3 Pages: 1-10
- DOI
  10.1038/ncomms2267
- NAID
  120007179832
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570110, KAKENHI-PROJECT-22310142, KAKENHI-PROJECT-22380049, KAKENHI-PUBLICLY-24102503
[Journal Article] "Lipopolysaccharide induces raft domain expansion in membrane composed of a phospholipid-cholesterol-sphingomyelin ternary system."2011
- Author(s)
  K. Nomura, M. Maeda, K. Sugase and S.Kusumoto
- Journal Title
  
  Innate Immun
  
  Volume: vol. 17 Pages: 256-268
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570127
[Journal Article] Lipopolysaccharide induces raft domain expansion in membrane composed of a phospholipid-cholesterol-sphingomyelin ternary system2011
- Author(s)
  Nomura K., Maeda M., Sugase K., Kusumoto S.
- Journal Title
  
  Innate Immun.
  
  Volume: Vol.17 Pages: 256-268
- DOI
  10.1177/1753425910365944
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570127
[Journal Article] Lipopolysaccharide Induces Raft Domain Expansion in Membrane Composed of a Phospholipid-Cholesterol-Sphingomyelin Ternary System.2010
- Author(s)
  Nomura K., Maeda M., Sugase K., Kusumoto S.
- Journal Title
  
  Innate Immunity Vol.
- Data Source
  KAKENHI-PROJECT-19550174
[Journal Article] A novel complete reconstruction system for membrane integration of the simplest membrane protein2010
- Author(s)
  Nishiyama K., Maeda M., Abe M., Kanamori T, himamoto K., Kusumoto S., Ueda T., and Tokuda H
- Journal Title
  
  Biochem.Biophys. Res. Commun
  
  Volume: 394 Pages: 733-736
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22310142
[Journal Article] Interaction of Lipopolysaccharide and Phospholipid in Mixed Membranes: Solid-State 31P-NMR Spectroscopic and Microscopic Investigations2008
- Author(s)
  Nomura K., Inaba T., Morigaki K., Brandenburg K., Seydel U., Kusumoto S.
- Journal Title
  
  Biophysical Journal Vol.95
  
  Pages: 1226-1238
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19550174
[Patent] 大腸菌膜タンパク質挿入因子2011
- Inventor(s)
  島本啓子、楠本正一、前田将秀、西山賢一、徳田元、上田卓也、金森崇
- Industrial Property Rights Holder
  公益財団法人サントリー生命科学財団
- Filing Date
  2011-03-04
- Overseas
- Data Source
  KAKENHI-PROJECT-22310142
[Presentation] 大腸菌膜タンパク質挿入に関わる新しい因子:機能と構造」2012
- Author(s)
  島本、前田、永瀬、楠本、西山
- Organizer
  新規素材探索研究会
- Place of Presentation
  横浜
- Year and Date
  2012-06-08
- Data Source
  KAKENHI-PROJECT-22310142
[Presentation] 大腸菌膜タンパク質挿入に関わる新しい因子MPIase の機能と構造2012
- Author(s)
  島本、前田、永瀬、柳澤、徳田、西山、楠本
- Organizer
  第31回日本糖質学会年会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-22310142
[Presentation] 大腸菌膜タンパク質挿入に関わる新規糖脂質MPIase の合成研究2012
- Author(s)
  永瀬、島本、前田、楠本、西山
- Organizer
  日本化学会第92春季年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22310142
[Presentation] 膜タンパク質挿入に関わる新規糖脂質の機能と構造2011
- Author(s)
  前田、西山、永瀬、岩下、小村、徳田、楠本、島本要
- Organizer
  第53回天然有機化合物討論会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22310142
[Presentation] タンパク質膜挿入に関与する新規複合糖脂質MPIase の構造と機能2011
- Author(s)
  西山、前田、島本、楠本、徳田
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22310142
[Presentation] 大腸菌膜タンパク質挿入に関わる新しい因子:機能と構造2011
- Author(s)
  島本、前田、永瀬、楠本、西山
- Organizer
  第14回生命化学研究会～ in cellinteractions を調べる・動かす・くみ上げる
- Place of Presentation
  和歌山
- Year and Date
  2011-12-03
- Data Source
  KAKENHI-PROJECT-22310142
[Presentation] Structure and Function of Novel Glycolipid Characterized as Membrane Protein 科研費新学術領域「天然物ケミカルバイオロジー:分子標的と活性制御」
- Author(s)
  島本、前田、永瀬、柳澤、徳田、西山、楠本
- Organizer
  第1回国際領域シンポジウム
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22310142

1. 小倉協三 (80006303)

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2. 杉浦幸雄 (40025698)

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7. MIURA Kaoru (90353515)

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8. 福本圭一郎 (50004586)

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16. SHIMAMOTO Keiko (70235638)

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17. FUKASE Koichi (80192722)

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18. SHIRAHAMA Haruhisa (00000802)

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48. 菅隆幸 (00033811)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
49. 林雄二 (40046917)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
50. 野老山喬 (90046938)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
51. 児玉三明 (30004378)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
52. 上江田捷博 (10145550)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
53. 上村大輔 (00022731)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
54. 奥村保明 (20021933)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
55. 加藤忠弘 (20004319)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
56. 加藤紀元 (00006305)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
57. 若宮建昭 (10028243)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
58. 徳田元

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KUSUMOTO Shoichi 楠本 正一

楠本 正一

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Chemical approach for the structure and function of key compounds in innate immunityPrincipal Investigator

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糖質の関与する超分子形成と機能Principal Investigator

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天然超分子化学の総合的研究Principal Investigator

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天然超分子の化学的研究Principal Investigator

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Structural and Synthetic studies of biologically active natural glycoconjugates and peptidesPrincipal Investigator

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糖質の精密構造認識と機能発現Principal Investigator

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KUSUMOTO Shoichi 楠本正一

楠本正一