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OHNISHI Yoshinari  大西 克成

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ONISHI Yoshinari  大西 克成

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Researcher Number 10037400
Other IDs
Affiliation (based on the past Project Information) *help 2004: The University of Tokushima, Institute of Health Biosciences, Department of Molecular Bacteriology, Professor, 大学院・ヘルスバイオサイエンス研究部, 教授
2003: 徳島大学, 医学研究科, 教授
1997 – 2001: 徳島大学, 医学部, 教授
1986 – 1995: 徳島大学, 医学部, 教授
Review Section/Research Field
Principal Investigator
Bacteriology (including Mycology) / Biological Sciences / Bacteriology (including Mycology) / 細菌学
Except Principal Investigator
Bacteriology (including Mycology) / 細菌学
Keywords
Principal Investigator
azoxymethane / Bacteroides fragilis / 環境変異原 / 代謝活性化 / 複合作用 / Lactobacillus acidophilus / Bacteroides uniformis / アレーン / クロロフィル / 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine … More / aberrant crypt foci / Clostridium perfringens / リコペン / 腸内菌 / リコペン産生大腸菌 / ラクトフェリン / 解毒 / 抱合反応 / PCR / Bifidobacterium adolescentis / DNA inversion / neuraminidase / 腸肝循環 / 抱合体 / ヘテロサイクリックアミン / 大腸癌 / 腸内フローラ / 抗生物質 / PhIP / ACF / 機能的腸内菌 / 大腸発がん / 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine(PhIP) / aberrant crypt foci(ACF) / ヒトラクトフェリン / レモングラス構成成分 / UDP-glucuronyltransferase / O^6-methylguanine / 機能性腸内菌 / ラクトフェリン産生腸内菌 / 発癌抑制 / 細胞障害活性 / YAC-1細胞 / プロバイオティクス / aberrant crypt foci (ACF) / ニトロアレーン / メンチルアレーン / wst突然変異マウス / 亜硝酸 / DNAプローブ / 迅速診断法 / ノイラミニダーゼ / DNA診断 / 感染症 / rRNAスペーサー領域 / DNA probe / Rapid detection method / Neuraminidase / DNA diagnosis / Infection / rRNA spacer region / 非ステロイド系抗炎症剤 / 小腸潰瘍 / 無菌動物 / ノトバイオート / 大腸菌 / Nonsteroidal antiinflammatry drug / Small intestinal ulcer / Intestinal bacteria / Germ-free rats / Gnotobiotes / Escherichia coli / ゲノム解析 / 複合糖鎖分解酵素 / シアロ複合糖鎖 / 敗血症 / 易感染性宿主 / 制限・修飾システム / Pathogenicity island / クラスター / 腫瘍形成 / pathogenicity island / 遺伝子破壊株 / 形質転換効率 / Genomic analysis / Glycosyl hydrolases / Sialoglycoconjugates / Sepsis / Compromised host / Restriction-modification system / バクテロイデス属 / 病原性 / 遺伝子クロ-ニング / ノイラミニダ-ゼ / DNA塩基配列 / 易動化 / エレクトロポレ-ション / 正の選択ベクタ- / 偏性嫌気性菌 / バクテロイデス / 遺伝子発現 / 遺伝子クローニング / neruaminidase / エレクトロポレーション / 組換え体選択ベクター / Bacteroides gingivalis / トリプシン様プロテアーゼ / DNase / shultle vector / Bacteroides / pathogenicity / gene cloning / DNA sequence / mobilization / electroporation / positive-selection vector … More
Except Principal Investigator
環境汚染物質 / 健康影響 / 複合要因 / 同時曝露 / 生体側要因 / 種差 / 性差 / DNA傷害 / 発がんイニシエ-タ- / DNA付加体 / 代謝的活性化 / チトクロムP-450 / ヘテロサイクリックアミン / ニトロピレン / HUS / Bacteroides fragilis / neuraminidase / Lactobacillus acidophilus / transit index / diclofenac / 人体影響 / 難分解性物質 / ダイオキシン / 磁場 / イニシエ-ション阻害因子 / sulfotransferase / TrpーPー2(NHOH) / PhIP / トニトロピレン / ファ-ジDNA組換え / クロロフィル / DNA組換え / 太陽性 / p53遺伝子 / スルホトランスフェラ-ゼ / 胆道がん / カ-ボンラジカル / 癌原物質 / 臓器特異性 / ヒドロキシアリ-ルアミン / 発がんイニシエーター / クロロフィリン / 抗変異原性 / 太陽光 / DNA非相同組換え / カーボンセンターラジカル / アリルスルホトランスフェラーゼ / サルフォトランスフェラ-ゼ / O-アセチラ-ゼ / チトクロムPー450 / サルフォトランスフェラーゼ / Oーアセチラーゼ / 化学発癌 / ヒトへの外挿 / N-水酸化体 / 細菌性病原因子 / 毒素遺伝子 / 転写調節 / 毒素の活性化 / 病原プラスミド / 赤痢菌 / 緑膿菌 / コレラ菌 / 病原細菌 / 病原因子 / 病原遺伝子 / 調節遺伝子 / DNA塩基配列 / 病原性プラスミド / 病原性ファージ / 病原細菌学 / 病原性の調節 / 調節遣伝子 / DNA塩基配例 / 溶原ファ-ジ / Bacterial pathogenesis / Toxin gene / Regulation of expression / Activation of toxin / Pathogenic plasmid / Shigella fiexneri / Pseudomonas aeruginosa / Vibrio cholerae / バクテロイデス / 同定 / ゲノム解析 / パルスフィールドゲル電気泳動法 / 進化系統樹 / 16S-23S スペーサー / 塩基配列 / DNAプローブ / 16S-23Sスペーサー / 制限酵素 / 分類 / Bacteroides / identification / genome analysis / PFGE / phylogenetic tree / 16S-23S spacer / nucletide sequence / DNA probe / 病原性 / 腸管毒性 / 細胞毒性 / 溶血活性 / 血中出現菌数 / Bacteroides fragills / Bacteroides uniformis / 腸管内液体貯留 / 貧血 / 血小板 / Vero細胞 / pathogenicity / enterotoxigenicity / cytotoxicity / heamolysis / bacteria in blood / 非ステロイド系抗炎症剤 / 小腸潰瘍 / グラム陰性桿菌 / 抗酸化剤 / 胆汁 / 脂質過酸化 / アスコルビン酸 / Escherichia coli / nonsteroidal antiinflammatory drug / small intestinal ulcer / Gram-negative rods / antioxidants / bile / 伝達性プラスミド / 膜透過性 / RNA分解 / 遺伝子発現 / RNAポリメラーゼ / リファンピシン / 転写 / transmissible plasmid / membrane permeability / RNA degradation / gene expression / RNA polymerase / rifampicin Less
  • Research Projects

    (28 results)
  • Co-Researchers

    (40 People)
  •  Analysis of infectious factors of Bacteroides fragilis in the compromised hostPrincipal Investigator

    • Principal Investigator
      OHNISHI Yoshinari
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      The University of Tokushima
  •  植物成分および機能性腸内菌による大腸発がんの防御機構の研究Principal Investigator

    • Principal Investigator
      大西 克成
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokushima
  •  生理活性物質産生腸内フローラによる疾病の予防と治療Principal Investigator

    • Principal Investigator
      大西 克成
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      The University of Tokushima
  •  発がん予防における腸内フローラの役割の解明と機能的腸内菌の開発Principal Investigator

    • Principal Investigator
      大西 克成
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokushima
  •  Mechanisms of inhibition of drug-induced ulcer formation by intestinal bacteria

    • Principal Investigator
      KEIKO Kataoka
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      The University of Tokushima, School of Medicine
  •  発がんとがん予防における腸内フローラの役割の解明と機能的腸内菌の開発Principal Investigator

    • Principal Investigator
      大西 克成
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokushima
  •  発がんとがん予防における腸内フローラの役割の解明と機能的腸内菌の開発Principal Investigator

    • Principal Investigator
      大西 克成
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokushima
  •  Identification and genome structure of the genes Bacteroides

    • Principal Investigator
      AKIMOTO Shigeru
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      Wakayama Medical College
  •  HUS development associated with bacterial infection and prevention against HUS

    • Principal Investigator
      KATAOKA Keiko
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      The University of Tokushima
  •  Development of the rapid identification system for Bacteroides fragilis by PCR with a DNA probe.Principal Investigator

    • Principal Investigator
      OHNISHI Yoshinari
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      University of Tokushima
  •  Role of intestinal bacteria in small intestinal ulcer formation and prevention in rats treated with a nonsteroidal antiinflammatory drug.Principal Investigator

    • Principal Investigator
      OHNISHI Yoshinari
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      The University of Tokushima
  •  発がんのイニシエ-ションとその阻害

    • Principal Investigator
      早津 彦哉
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Okayama University
  •  環境複合汚染の生体影響と関連要因

    • Principal Investigator
      井上 圭三
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  環境複合汚染の生体影響と関連要因

    • Principal Investigator
      井上 圭三
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  発がんのイニシェ-ションとその阻害

    • Principal Investigator
      早津 彦哉
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Okayama University
  •  化学発癌における活性中間体の動態と標的臓器DNA傷害ー臓器および種特異性との関連

    • Principal Investigator
      加藤 隆一
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Keio University
  •  環境複合汚染の生体影響と関連要因

    • Principal Investigator
      井上 圭三
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  発がんのイニシエ-ションとその阻害

    • Principal Investigator
      早津 彦哉
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Okayama University
  •  Molecular Genetics of Micrbial Pathogenesis

    • Principal Investigator
      TERAWAKI Yoshiro
    • Project Period (FY)
      1990 – 1993
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      細菌学
    • Research Institution
      Shinshu University
  •  環境要因の人体影響(基礎班)

    • Principal Investigator
      武部 啓
    • Project Period (FY)
      1987 – 1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  環境変異原の生体円代謝と複合作用Principal Investigator

    • Principal Investigator
      大西 克成
    • Project Period (FY)
      1987 – 1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokushima
  •  環境変異原の生体代謝と複合作用Principal Investigator

    • Principal Investigator
      大西 克成
    • Project Period (FY)
      1987 – 1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokushima
  •  癌原物質の代謝的活性化機構と発癌の特異性に関する研究ーー特にヒトの外挿

    • Principal Investigator
      加藤 隆一
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Keio University
  •  環境変異原の生体内代謝と複合作用Principal Investigator

    • Principal Investigator
      大西 克成
    • Project Period (FY)
      1987 – 1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokushima
  •  Molecular genetic studies on pathogenicity of genus Bacteroides.Principal Investigator

    • Principal Investigator
      OHNISHI Yoshinari
    • Project Period (FY)
      1987 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      細菌学
    • Research Institution
      The University of Tokushima
  •  癌原物質の代謝的活性化機構と発癌の特異性に関する研究ー特にヒトへの外挿

    • Principal Investigator
      加藤 隆一
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Keio University
  •  Transmissible plasmid genes increase membrane permeability: function and regulatory mechamism of gene expression.

    • Principal Investigator
      AKIMOTO Shigeru
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      細菌学
    • Research Institution
      The University of Tokushima
  •  癌原物質の代謝的活性化機構と発癌の特異性に関する研究-特にヒトへの外挿-

    • Principal Investigator
      加藤 隆一
    • Project Period (FY)
      1985 – 1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Keio University
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    # of Collaborated Projects: 9 results
    # of Collaborated Products: 0 results
  • 2.  渡部 烈 (00057316)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 3.  KUWAHARA Tomomi (60263810)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 4.  ARIMOCHI Hideki (30311822)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 5.  長尾 美奈子 (40100151)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 6.  早津 彦哉 (10012593)
    # of Collaborated Projects: 6 results
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  • 9.  山添 康 (00112699)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 10.  KINOUCHI Takemi (80136217)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 11.  AKIMOTO Shigeru (10159337)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 12.  井村 伸正 (70012606)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 13.  加藤 隆一 (40112685)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 14.  辰巳 淳 (90037581)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 15.  根岸 和雄 (70116490)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 16.  井上 圭三 (30072937)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 17.  加須屋 実 (50045382)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 18.  岡田 昌二 (40046256)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 19.  出川 雅邦 (50134002)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 20.  渡辺 民朗 (40006101)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 21.  ONO Tsuneko (40035514)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 22.  池田 日出男 (10012775)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 23.  大垣 比呂子 (00150201)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 24.  TERAWAKI Yoshiro (10014333)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  SASAKAWA Chihiro (70114494)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  IKE Yasuyoshi (60125820)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  NAKAZAWA Teruko (40053053)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  AMAKO Kazunobu (20078752)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  武部 啓 (10028318)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  池永 満生 (70025378)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  嶋 昭絋 (60011590)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  志賀 健 (10028350)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  石川 隆俊 (30085633)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  多田 万里子 (90073113)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  若林 敬二 (60158582)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  江角 浩安 (70160364)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  井上 公蔵 (10028300)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  江崎 孝行 (90151977)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 39.  西渕 光昭 (50189304)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 40.  KAMOGASHIRA Takashi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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