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DAIKUHARA Yasushi
大工原 恭
Connect your ORCID iD
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Alternative Names
大工原 泰 ダイクハラ ヤスシ
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Researcher Number
40028733
External Links
Affiliation (based on the past Project Information)
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2003: Kagoshima University, Graduate School of Medical and Dental Sciences, Professor, 大学院・医歯学総合研究科, 教授
1993 – 2002: 鹿児島大学, 歯学部, 教授
1989 – 1991: 鹿児島大学, 歯学部, 教授
1987: Professor, Kagoshima University Dental School, 歯学部, 教授
Review Section/Research Field
Principal Investigator
Functional basic dentistry
/
Biological Sciences
Except Principal Investigator
Functional basic dentistry
Keywords
Principal Investigator
肝細胞増殖因子(HGF) / 細胞分散因子(SF) / 肝細胞 / c-Met / 肝疾患 / 肝細胞増殖因子 / 第一鰓弓 / myogenin / 高感度ELISA / 骨芽細胞
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More
/ フェチュイン / 骨吸収 / Fetuin / Bone resorption / Hepatocyte growth factor / 増殖因子 / 細胞増殖 / 脾臓 / サイトカイン / HGF / 舌 / 泌尿器系腫瘍 / 尿試料 / myoD / Osteoblast / Hepatocyte / 副甲状腺ホルモン / α2-HS糖タンパク / Parathyroid hormone / 歯周疾患 / 診断法 / 歯肉溝滲出液 / Scatter factor / 肝臓 / 癌転移 / 癌抑制因子 / プロHGF / HGF活性化酵素 / 肝再生 / 筋芽細胞 / 増殖 / 分化 / MyoD / 酵素抗体法(ELISA) / Fab' / IgY / 診断薬 / 培養筋芽細胞 / マトリックスメタロプロテアーゼ(MMP) / PI3K / gelatinase / 舌芽器官培養 / シアロタンパク / 糖タンパク / α_2ーHS 糖タンパク / α_2ーHS glycoprotein / 骨 / 象牙質 / 血漿 / 石灰化 / モノクロ-ナル抗体 / 細胞外基質 / Sialoprotein / Glycoprotein / Alpha_2-HS glycoprotein / リン酸化型フェチュイン / 脱リン酸化型フェチュイン / α_2-HS糖タンパク / カローン / リン酸化型ラットフェチュイン / 脱リン酸化型ラットフェチュイン / 組換え体発現 / 昆虫細胞 / Phosphorylated fetuin / Non-phosphorylated fetuin / alpha_2-HS glycoprotein / Hepatocyte growth factor (HGF) / Chalone / ラット / 血清濃度 / 甲状腺ホルモン / ラットフェチュイン / カテプシンL / Rat / Serum concentration / 上皮細胞分散因子 / 歯肉溝浸出液 / 組織修復 / 歯周炎 / SF / ELISA / 高感度化 / Periodontal disease / Diagnosis / Gingival cervical fluid / High sensitive ELISA / Tissue erpair / 下顎骨 / 舌発生 / myo D / 細胞遊走 / myf5 / フェチェイン / 骨発生 / 骨形成タンパク / First branchial arch / Mandible / Development of tongue / HGF-活性化酵素(HGFA) / 高感度HGF ELISA / アルツハイマー病 / 脳血栓 / 歯肉組織 / HGF-activator / hepatocyte growth factor (HGF) / scatter factor / (SF) / periodontal disease / gingival crevicular fluid / HGF-activator (HGFA) / highly sensitive ELISA for HGF
…
More
Except Principal Investigator
HGF / SF / NO / 増殖因子 / サイトカイン / チロシンキナーゼ受容体 / 細胞接着分子 / ERMファミリー / 癌抑制遺伝子 / 肝細胞増殖因子(HGF) / c-Met / がん細胞の増殖制御 / MAPキナーゼ / Hrs結合蛋白質 / SH3ドメイン / 脱ユビキチン化酵素 / 肝細胞増殖因子 / がん細胞の浸潤性 / Ras蛋白質 / 細胞増殖制御 / c-Met受容体 / ErbBリガンド / HEP受容体 / スルホニール尿素受容体 / インスリンシグナル伝達系 / ErbB3 / HB-EGF / ガストリン受容体 / ソマトスタチン / GLUT4のトランスロケーション / Gas6 / Sky / 細胞増殖抑制 / インスリン受容体 / c-kit受容体 / がん遺伝子 / がん抑制遺伝子 / シグナル伝達 / がん細胞 / がん転移 / DNA修復 / ヒトゲノム / 2国間共同研究 / がん遣伝子 / がん抑制遣伝子 / International Exchange Program / French-Japanese Collaborative Program in Cancer Research / German-Japanese Collaborative Program in Cancer Research / Oncogenes / Tumor Suppressor Genes / Signal Transduction / DNA Repair / Cancer Metastasis / 一酸化窒素 / フリーラディカル / 歯周炎 / 糖尿病 / DIABETES / PERIODONTITIS / FREE RADICAL / 象牙質 / 骨 / フォスフォフォリン / 石灰化 / モノクローナル抗体 / 骨由来非コラーゲン性タンパク質 / りん蛋白質 / Dentin / bone / phosphophoryn / calcification / monoclonal antibody
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Research Projects
(
18
results)
Co-Researchers
(
59
People)
Project Start Year (Newest)
Project Start Year (Oldest)
Induction of angiogenesis by hepatocyte growth factor and nitric oxide in periodontitis
Principal Investigator
OHNISHI Tomokazu
Project Period (FY)
2002 – 2003
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Functional basic dentistry
Research Institution
Kagoshima University
舌の形成・再生におけるHGFの役割―マウス舌胚の器官培養によるアプローチ―
Principal Investigator
Principal Investigator
大工原 恭
Project Period (FY)
2001 – 2002
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Functional basic dentistry
Research Institution
Kagoshima University
尿中HGF測定による泌尿器系腫瘍の新しい診断法の確立
Principal Investigator
Principal Investigator
大工原 恭
Project Period (FY)
2000
Research Category
Grant-in-Aid for Scientific Research on Priority Areas (C)
Review Section
Biological Sciences
Research Institution
Kagoshima University
A basic research for use of hepatocyte growth factor (HGF) for diagnosis and treatment of periodontal disease.
Principal Investigator
Principal Investigator
DAIKUHARA Yasushi
Project Period (FY)
2000 – 2002
Research Category
Grant-in-Aid for Scientific Research (A)
Research Field
Functional basic dentistry
Research Institution
Kagoshima University
肝細胞増殖因子受容体(c-Met)を介するシグナル伝達の分子機構
Principal Investigator
喜多村 直実 (喜多村 直美)
Project Period (FY)
1999
Research Category
Grant-in-Aid for Scientific Research on Priority Areas (A)
Research Institution
Tokyo Institute of Technology
尿中HGF測定による泌尿器系腫瘍の早期診断法の開発
Principal Investigator
Principal Investigator
大工原 恭
Project Period (FY)
1999
Research Category
Grant-in-Aid for Scientific Research on Priority Areas (A)
Research Institution
Kagoshima University
Effect of hepatocyte growth factor/scatter factor on the development and metabolism of bone tissue : relation of regulation on fetuin gene expression.
Principal Investigator
Principal Investigator
DAIKUHARA Yasushi
Project Period (FY)
1998 – 2000
Research Category
Grant-in-Aid for Scientific Research (B).
Research Field
Functional basic dentistry
Research Institution
Kagoshima University
筋芽細胞に対するHGFの作用-舌再建へのアプローチ-
Principal Investigator
Principal Investigator
大工原 恭
Project Period (FY)
1997 – 1998
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Functional basic dentistry
Research Institution
Kagoshima University
Physiological roles of rat fetuin on bone metabolism
Principal Investigator
Principal Investigator
DAIKUHARA Yasushi
Project Period (FY)
1996 – 1997
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Functional basic dentistry
Research Institution
Kagoshima University
A new diagnostic method for periodontal diseases by determining hepatocyte growth factor in gingival cervical fluid with a high sensitive ELISA.
Principal Investigator
Principal Investigator
DAIKUHARA Yasushi
Project Period (FY)
1996 – 1998
Research Category
Grant-in-Aid for Scientific Research (A)
Research Field
Functional basic dentistry
Research Institution
Kagoshima University
ヒト肝細胞増殖因子(hHGF)の活性化及び不活性化機構-病態との関連-
Principal Investigator
Principal Investigator
大工原 恭
Project Period (FY)
1994
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Kagoshima University
Difference in physiological roles of phosphorylated and non-phosphorylated rat fetuin.
Principal Investigator
Principal Investigator
DAIKUHARA Yasushi
Project Period (FY)
1994 – 1995
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Functional basic dentistry
Research Institution
Kagoshima University
細胞増殖因子からみた癌細胞と間質細胞との相互作用 -その分子機構-
Principal Investigator
田原 榮一
Project Period (FY)
1993
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Hiroshima University
ヒト肝細胞増殖因子(hHGF)の合成・分泌調節機構
Principal Investigator
Principal Investigator
大工原 恭
Project Period (FY)
1991
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Kagoshima University
Cooperation and information exchange with European countries.
Principal Investigator
KUROKI Toshio
Project Period (FY)
1991 – 1993
Research Category
Grant-in-Aid for international Scientific Research
Research Institution
University of Tokyo
ヒト肝細胞増殖因子(hHGF)の合成・分泌調節機構
Principal Investigator
Principal Investigator
大工原 恭
Project Period (FY)
1990
Research Category
Grant-in-Aid for Cancer Research
Research Institution
Kagoshima University
Studies on Relation Between Calcification of Tissues and Biosynthesis of a 59 kDa Sialoprotein from Rat Mandible, Using a Monoclinal Antibody.
Principal Investigator
Principal Investigator
DAIKUHARA Yasushi
Project Period (FY)
1989 – 1990
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Functional basic dentistry
Research Institution
Kagoshima University
Tissue distribution and purification of Phosphophoryn an approach using the monoclonal antibody
Principal Investigator
NAKAMA Takako
Project Period (FY)
1986 – 1987
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Functional basic dentistry
Research Institution
Kagoshima University
# of Projects (Dsc)
# of Projects (Asc)
1.
AMITA YASUDA Yoko
(70274850)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
2.
ARAKAKI Naokatu
(60151148)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
3.
OHNISHI Tomokazu
(30244247)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
4.
HIRONO Shuichi
(00181222)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
5.
KAJIHARA Takehiro
(10305138)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
6.
NAKAMURA Osamu
(70128445)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
7.
KOKUBO Akiko
(90304534)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
8.
MATIGASHIRA Miho
(80253897)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
9.
西山 賢龍
(80264422)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
10.
KAKIMOTO Kyoko
(40274849)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
11.
坪内 博仁
(60145480)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
12.
中河 志朗
(70073666)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
13.
喜多村 直実
(80107424)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
14.
KUROKI Toshio
(90006073)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
15.
NIKAIDO Osamu
(60019669)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
16.
SEKI Shuji
(50032884)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
17.
TANAKA Kiyoji
(80144450)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
18.
HANAOKA Fumio
(50012670)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
19.
MAKI Hisaji
(20199649)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
20.
ISHIKAWA Takatoshi
(30085633)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
21.
SEKIGUCHI Mutsuo
(00037342)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
22.
TOMOMURA Akito
(60188810)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
23.
TAMURA Masato
(30236757)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
24.
BANDOW Kenjiro
(50347093)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
25.
NAKAMA Takako
(60128444)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
26.
田原 榮一
(00033986)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
27.
井出 利憲
(60012746)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
28.
河野 通明
(00027335)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
29.
松本 邦夫
(90201780)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
30.
宮崎 博臣
(30166152)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
31.
伝田 公紀
(50212064)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
32.
蛯名 洋介
(00112227)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
33.
清野 進
(80236067)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
34.
松井 利充
(10219371)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
35.
東山 繁樹
(60202272)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
36.
許 南浩
(70173573)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
37.
中島 元夫
(90240738)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
38.
瀬戸 加大
(80154665)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
39.
長田 重一
(70114428)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
40.
相沢 慎一
(60073011)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
41.
堀井 明
(40249983)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
42.
広橋 説雄
(70129625)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
43.
奥村 康
(50009700)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
44.
勝木 元也
(20051732)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
45.
山岸 秀夫
(90025429)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
46.
伊藤 嘉明
(80004612)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
47.
平野 俊夫
(40136718)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
48.
菊谷 仁
(80161412)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
49.
谷口 維紹
(50133616)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
50.
豊島 久真男
(90029760)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
51.
中村 祐輔
(70217909)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
52.
吉田 廸弘
(60001765)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
53.
貝淵 弘三
(00169377)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
54.
御子柴 克彦
(30051840)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
55.
稲垣 昌樹
(30183007)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
56.
月田 承一郎
(50155347)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
57.
西村 暹
(20076970)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
58.
清水 孝男
(80127092)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
59.
HUH Nam-ho
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
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