• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Tsumoto Kouhei  津本 浩平

ORCIDConnect your ORCID iD *help
… Alternative Names

TSUMOTO Kouhei  津本 浩平

Less
Researcher Number 90271866
Other IDs
External Links
Affiliation (Current) 2021: 東京大学, 大学院工学系研究科(工学部), 教授
2021: 国立研究開発法人医薬基盤・健康・栄養研究所, 医薬基盤研究所 創薬デザイン研究センター, 招へい副センター長
Affiliation (based on the past Project Information) *help 2016 – 2020: 東京大学, 大学院工学系研究科(工学部), 教授
2013 – 2017: 東京大学, 大学院工学系研究科, 教授
2012 – 2015: 東京大学, 工学(系)研究科(研究院), 教授
2014: 東京大学, 工学系研究科, 教授
2010 – 2011: 東京大学, 医科学研究所, 教授 … More
2007 – 2009: The University of Tokyo, Graduate School of Frontier Sciences, Associate Professor
2006: 東京大学, 大学院新領域創成科学研究科, 助教授
2006: The University of Tokyo, Graduate School of Frontier Sciences, Associate Professor, 新領域創成科学研究科, 助教授
2005: 東京大学, 大学院・新領域創成科学研究科, 助教授
2002 – 2004: 東北大学, 大学院・工学研究科, 助教授
2001: 東北大学, 大学院・工学研究科, 講師
1997 – 2000: 東北大学, 大学院・工学研究科, 助手
1996 – 1998: 東北大学, 工学部, 助手 Less
Review Section/Research Field
Principal Investigator
Biophysics / Science and Engineering / Biofunction/Bioprocess / Biofunction/Bioprocess / Complex systems / Molecular biology / 生物・生体工学 / Basic Section 27040:Biofunction and bioprocess engineering-related
Except Principal Investigator
Biological Sciences / Science and Engineering … More / Biofunction/Bioprocess / Cell biology / Biomolecular chemistry / Engineering / Chemistry / Digestive surgery / 生物・生体工学 / Functional materials chemistry / Otorhinolaryngology / Biomedical engineering/Biomaterial science and engineering / Chemical engineering and related fields / Pathology, Infection/Immunology, and related fields / Medium-sized Section 50:Oncology and related fields Less
Keywords
Principal Investigator
蛋白質 / 相互作用 / 分子認識 / 抗体 / 蛋白質間相互作用 / 特異性 / 生物・生体工学 / バイオテクノロジー / 熱力学 / 物理化学 … More / 熱量測定 / 蛋白質工学 / X線結晶構造解析 / 可溶化 / 生体分子 / 繊維状ファージ / 抗原抗体反応 / 可変領域断片 / 親和性 / 進化工学 / ファージ提示系 / 抗原抗体相互作用 / 蛋白性抗原 / 熱力学的解析 / 変異体 / 非共有結合 / 細胞表面抗原 / がん細胞 / ファージディスプレイ / EGFR / 融合蛋白質 / ファージ提示法 / MUCI / 癌免疫療法 / 抗体ライブラリー / 膜蛋白質 / MUC1 / 後退ライブラリー / 受容体 / 生物物理 / シグナル伝達 / ナノバイオ / 天然変性 / スクリーニング / 低分子創薬 / 熱力学解析 / フラグメントスクリーニング / 低分子スクリーニング / 溶媒・添加剤 / アルギニン / クロマトグラフィー / 凝集会合形成 / フィロールディング / 製剤 / プロテインマニピュレーション / リフォールディング / PROTEIN / BIOTECHNOLOGY / BIOMOLECULE / BIO-ENGINEERING / 蛋白質-蛋白質相互作用 / 低分子 / 阻害剤 / 速度論 / 創薬 / 薬学 / 遷移状態 / 生命金属科学 / 生物無機化学 / 金属細胞生物学 / 生命金属 / 有害金属 / 病原性微生物 / 金属取り込み / 低分子化抗体 / 低分子化合物 / 蛋白質エンジニアリング / ダイナミクス … More
Except Principal Investigator
分子認識 / 抗原抗体相互作用 / 抗体 / X線結晶構造解析 / 結晶構造解析 / バイオテクノロジー / 構造解析 / 不溶性顆粒 / 巻き戻し系 / 自然免疫 / 熱力学的解析 / 蛋白質間相互作用 / 変異導入 / ファージ提示法 / タンパク質相互作用 / 高分子ミセル / グルコーストランスポーター / SEA / GFP / Prestin / キメラ受容体 / 細胞増殖 / 融合蛋白質 / 抗体-受容体キメラ蛋白質 / エリスロポエチン受容体 / 卷き戻し系 / TCR-HLA相互作用 / ILT-HLA相互作用 / 表面プラズモン共鳴 / 等温滴定型熱量測定 / 受容体 / 細胞性免疫 / T細胞受容体 / ヒト白血球抗原 / 抗原 / 特異性・親和性 / 熱力学 / 相補性 / バイオインターフェイス / ペプチド移植 / マテリアル認識抗体 / 酸化亜鉛認識抗体 / 金表面特異的抗体 / 高機能性非天然型抗体 / 無作為変異導入 / CDR移植 / マテリアル認識ペプチド / diabody / 二重特異性抗体 / 非天然型組換え抗体 / ヒトFc受容体 / 親和性成熟 / 生細胞パニング / 非天然型抗体 / ナノ材料 / 細胞表面抗原 / 抗体工学 / Hot-Spot / ファージディスプレイ / ERK / MAPキナーゼ / リン酸化 / 細胞内情報伝達 / 細胞運動 / 抗リン酸化抗体 / プロテオーム / ダイニン / 細胞接着 / 細胞間接着 / 糸球体 / がん化 / 敗血症 / ヒストン障害 / ペントラキシン / RNAプロセッシング / 細胞周期 / パターン認識受容体 / オルタナティブスプライシング / 血管内皮細胞 / ヒストン / スプライシング / コンピュータシミュレーション / 生物機能工学 / タンパク質 / ナノバイオ / ブロック共重合体 / ポリエチレングリコール / ポリアミノ酸 / 薬物送達システム / 血液脳関門（BBB） / siRNA / アンチセンス核酸 / メッセンジャーRNA / プラスミドDNA / 抗体医薬 / 遺伝子治療 / 脳-血液関門 / アルツハイマー病 / 脳一血液関門 / 脳―血液関門 / グルコーストランスポ-ター / 養子免疫療法 / 胆管癌 / バイスペシフィク抗体 / MUC1 / MUSE11 / 一本鎖抗体 / MUC-1 / scFu / Bispecific抗体 / LAK細胞 / MVC1 / CD_3 / CD_<28> / Adoptive immunotherapy / Cholangiocarcinoma / Bispecific antibody / MUC 1 / MUSE 11 / single chain Fv / 自己抗原 / 発現系 / 巻き戻しシステム / 蛋白性抗原 / 変異体 / 非共有結合 / ANTIBODY / PHAGE-DISPLAY SYSTEM / MUTAGENESIS / AUTOANTIGENS / CRYTAL STRUCTURE / EXPRESSION SYSTEM / MOLECULAR RECOGNITION / REFOLDING SYSTEM / シャペロニン / 分子シャペロン / フォトクロミック分子 / アゾベンゼン / AND論理回路 / 分子機械 / 光異性化 / GroEL / リフォールディング / Chaperonin / Molecular Chaperon / Photochromic Molecule / Azobenzene / AND Logic Gate / 耳科学 / 蛋白質 / 分子モータ / 原子間力顕微鏡 / 精製 / 等温滴定カロリメトリー / 生物物理 / 走査プローブ顕微鏡 / パッチクランプ法 / 等温滴定型カロリメトリー / 国際研究者交流 / アメリカ / 膜タンパク質 / Otology / Protein / Molecular motor / Atomic force microscopy / Purification / Isothermal titration calorimetry / Glucose transporter / 核酸医薬 / ヘテロ核酸 / 神経変性疾患 / リサイクリング / Glut / 核酸 / ハイドロゲル / レクチン / TSG-6 / 炎症 / リンクモジュール / 医用化学工学 / バイオマテリアル / 再生医学 / ヒアルロン酸 / A群レンサ球菌 / 鉄獲得系 / Shr / ヘム鉄 / 増殖阻害薬 / 低分子化合物 / スクリーニング / 鉄取り込み / 単分子抗体 / 機能阻害 / 細菌感染症 / 菌種特異的増殖阻害剤 / 分子間相互作用 / 分子標的薬 / 免疫チェックポイント阻害剤 / mRNA / 膠芽腫 / がん免疫療法 Less

  • Research Projects

    (31 results)

  • Research Products

    (535 results)

  • Co-Researchers

    (127 People)

  •  蛋白質エンジニアリングにおけるローカルフラクチュエーションの解明とその制御Principal InvestigatorOngoing

    • Principal Investigator
      津本 浩平
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 27040:Biofunction and bioprocess engineering-related
    • Research Institution
      The University of Tokyo

  •  Integrated Biometal Science: Research to Explore Dynamics of Metals in Cellular SystemArea Organizer

    • Area Organizer
      津本 浩平
    • Project Period (FY)
      2019 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

  •  Integrated Biometal Science: Research to Explore Dynamics of Metals in Cellular SystemPrincipal InvestigatorOngoing

    • Principal Investigator
      津本 浩平
    • Project Period (FY)
      2019 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      The University of Tokyo

  •  生命金属動態の理解と制御のための分子認識素子の開発Principal InvestigatorOngoing

    • Principal Investigator
      津本 浩平
    • Project Period (FY)
      2019 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      The University of Tokyo

  •  Pioneering glioblastoma therapy by in situ mRNA-based amplification of immune checkpoint inhibitorsOngoing

    • Principal Investigator
      片岡 一則
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Challenging Research (Pioneering)
    • Review Section
      Medium-sized Section 50:Oncology and related fields
    • Research Institution
      Kawasaki Institute of Industrial Promotion Innovation Center of NanoMedicine

  •  Development of heteroduplex oligonucleotide crossing the blood-brain barrierOngoing

    • Principal Investigator
      横田 隆徳
    • Project Period (FY)
      2017 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Biomedical engineering/Biomaterial science and engineering
    • Research Institution
      Tokyo Medical and Dental University

  •  Development of novel in situ crosslinked hydrogel using lectins

    • Principal Investigator
      Ito Taichi
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Research Field
      Chemical engineering and related fields
    • Research Institution
      The University of Tokyo

  •  Development of species-specific anti-bacterial therapeutic agents based on molecular interaction

    • Principal Investigator
      NAKAGAWA ICHIRO
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Research Field
      Pathology, Infection/Immunology, and related fields
    • Research Institution
      Kyoto University

  •  Screening and design of ligands regulating the process of protein-protein interactions based on biophysical approachesPrincipal Investigator

    • Principal Investigator
      Tsumoto Kouhei
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biofunction/Bioprocess
    • Research Institution
      The University of Tokyo

  •  Dynamics of Molecular Pattern Recognition in Protein Interaction

    • Principal Investigator
      HAMAKUBO TAKAO
    • Project Period (FY)
      2013 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Biomolecular chemistry
    • Research Institution
      The University of Tokyo

  •  Ligand discovery based on biophysical analysesPrincipal Investigator

    • Principal Investigator
      Tsumoto Kouhei
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biofunction/Bioprocess
    • Research Institution
      The University of Tokyo

  •  Development of Polymeric Micelles for Brain-Targeted Delivery of Nucleic Acid Drugs to Treat Intractable Neurological Diseases

    • Principal Investigator
      KATAOKA Kazunori
    • Project Period (FY)
      2013 – 2017
    • Research Category
      Grant-in-Aid for Specially Promoted Research
    • Review Section
      Science and Engineering
      Chemistry
    • Research Institution
      Kawasaki Institute of Industrial Promotion Innovation Center of NanoMedicine
      The University of Tokyo

  •  Bio-design for interface molecules in nano scale

    • Principal Investigator
      KUMAGAI IZUMI
    • Project Period (FY)
      2012 – 2016
    • Research Category
      Grant-in-Aid for Specially Promoted Research
    • Review Section
      Science and Engineering
      Engineering
    • Research Institution
      Tohoku University

  •  Analysis of regulatory mechanisms of newly identified ERK substrates

    • Principal Investigator
      KOSAKO Hidetaka
    • Project Period (FY)
      2011 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cell biology
    • Research Institution
      The University of Tokushima

  •  Structural and Functional Analyses of Intrinsically Unfolded Proteins for EngineeringPrincipal Investigator

    • Principal Investigator
      TSUMOTO Kouhei
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biofunction/Bioprocess
    • Research Institution
      The University of Tokyo

  •  蛋白質相互作用における多重特異性の定量的記述と応用Principal Investigator

    • Principal Investigator
      津本 浩平
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Science and Engineering
    • Research Institution
      The University of Tokyo

  •  受容体分子認識における多重特異性発現機構の定量的解明Principal Investigator

    • Principal Investigator
      津本 浩平
    • Project Period (FY)
      2006
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Science and Engineering
    • Research Institution
      The University of Tokyo

  •  Structural and functional analysis of the motor protein prestin using purified protein

    • Principal Investigator
      WADA Hiroshi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Tohoku University

  •  Development of a novel system for solubilization and preparation of proteins based on the aggregation suppression effects of arginine on proteinsPrincipal Investigator

    • Principal Investigator
      TSUMOTO Kouhei
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biofunction/Bioprocess
    • Research Institution
      The University of Tokyo

  •  Fabrication of dynamic materials using molecular chaperons

    • Principal Investigator
      KINBARA Kazushi
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional materials chemistry
    • Research Institution
      The University of Tokyo

  •  抗原抗体反応における特異性・親和性創出と水分子との関連に関する実験的考察

    • Principal Investigator
      熊谷 泉
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Science and Engineering
    • Research Institution
      Tohoku University

  •  Protein Engineering for Construction of Bio-interfaces

    • Principal Investigator
      KUMAGAI Izumi
    • Project Period (FY)
      2004 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Biofunction/Bioprocess
    • Research Institution
      Tohoku University

  •  細胞表面抗原特異的ヒト抗体の網羅的選択・調製と応用Principal Investigator

    • Principal Investigator
      津本 浩平
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Young Scientists (A)
    • Research Field
      生物・生体工学
    • Research Institution
      Tohoku University

  •  構造情報に基づく細胞性免疫システムにおける特異的分子認識機構の解明

    • Principal Investigator
      熊谷 泉
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University

  •  GENERATION AND UTILIZATION OF NOVEL HUMAN ANTIBODY MOLECULES BASED ON GENETIC INFORMATION

    • Principal Investigator
      KUMAGAI Izumi
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      生物・生体工学
    • Research Institution
      Tohoku University

  •  構造情報に基づく抗原抗体反応の精密解析と特異性・親和性を決定する因子の抽出Principal Investigator

    • Principal Investigator
      津本 浩平
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Biophysics
    • Research Institution
      Tohoku University

  •  シグナル伝達機構解析を目指した抗体-受容体キメラ蛋白質の創製と構造解析

    • Principal Investigator
      熊谷 泉
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University

  •  新機能抗体-受容体キメラ蛋白質の創製と細胞増殖制御機構解析への応用

    • Principal Investigator
      KUMAGAI Izumi
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University

  •  抗体分子の人工設計を目指す抗原抗体相互作用の精密解析Principal Investigator

    • Principal Investigator
      津本 浩平
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Biophysics
    • Research Institution
      Tohoku University

  •  Establishment of the adoptive anticancer immunotherapy for the unresectable cholangiocarcinoma using the bispecific antibody - Construction of bacterial expression system of bispecific antibodies

    • Principal Investigator
      SUZUKI Masanori
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      TOHOKU UNIVERSITY

  •  新規なファージベクター系を利用した抗体分子の機能改変Principal Investigator

    • Principal Investigator
      津本 浩平
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Molecular biology
    • Research Institution
      Tohoku University

All 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book Patent

  • [Book] 第19章　抗体医薬の基礎物性評価 医薬品原薬の結晶化と物性評価:その最先端技術と評価の実際2019
    • Author(s)
      津本浩平, 長門石曉
    • Total Pages
      10
    • Publisher
      シーエムシー出版
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Book] 材料創製を指向したタンパク質相互作用解析 高分子, 68巻3月号2019
    • Author(s)
      長門石曉, 中木戸誠, 津本浩平
    • Total Pages
      2
    • Publisher
      高分子学会
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Book] 黄色ブドウ球菌の鉄取り込み機構：Isdシステム 生化学, 90(3), 279-2892018
    • Author(s)
      Jose M. M. Caaveiro, 津本浩平
    • Total Pages
      11
    • Publisher
      日本生化学会
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Book] 薬学雑誌, 138(8), 1033-10412018
    • Author(s)
      長門石曉, Jose M. M. Caaveiro, 津本浩平 次世代の低分子創薬を拓くタンパク質-低分子間相互作用の物理化学的解析
    • Total Pages
      9
    • Publisher
      日本薬学会
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Book] タンパク質相互作用の創薬－物理化学を介して 生体の科学, Vol.69, No.4, 349-3532018
    • Author(s)
      長門石曉, 津本浩平
    • Total Pages
      5
    • Publisher
      医学書院
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Book] 神経難病と抗体医薬による分子標的治療 医薬ジャーナル　2018年7月号 Vol.54, No.7, 1607-16112018
    • Author(s)
      中木戸誠, 津本浩平
    • Total Pages
      5
    • Publisher
      医薬ジャーナル社
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Book] バイオ医薬品の分析のコツ　品質評価のための基礎と応用（第７回）タンパク質の分子間相互作用 PHARM TECH JAPAN 2018年2月号 Vol.34 No.2, 339-3452018
    • Author(s)
      津本浩平, 長門石曉, 中木戸誠, 黒田大祐
    • Total Pages
      7
    • Publisher
      株式会社じほう
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Book] コンピュータ技術による抗体分子設計 実験医学 2018年7月 Vol.36, No.11, 1859-18662018
    • Author(s)
      黒田大祐, 津本浩平
    • Total Pages
      8
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Book] CSJカレントビュー　医療・診断・創薬の化学　医療応用のための物理化学2017
    • Author(s)
      津本浩平、長門石曉（分担執筆）
    • Total Pages
      6
    • Publisher
      化学同人
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Book] 生体分子化学　8章　酵素2017
    • Author(s)
      長門石曉、津本浩平（分担執筆）
    • Total Pages
      27
    • Publisher
      講談社
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Book] サイエンスシグナリングジャパン2015
    • Author(s)
      太期　健二、津本　浩平、浜窪　隆雄
    • Total Pages
      2
    • Publisher
      米国科学振興協会
    • Data Source
      KAKENHI-PROJECT-25220205

  • [Book] 実験医学 研究成果を薬につなげるアカデミア創薬の戦略と実例：化合物の“質”を評価する新しいスクリーニング系2014
    • Author(s)
      長門石曉、津本浩平
    • Total Pages
      220
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-25249115

  • [Book] 技術レポート２０２３：物理化学的スクリーニング技術による創薬戦略と展望2013
    • Author(s)
      長門石曉、津本浩平
    • Total Pages
      324
    • Publisher
      日本能率協会総合研究所
    • Data Source
      KAKENHI-PROJECT-25249115

  • [Book] 生化学事典「クロマトグラフィー」「界面活性剤」2012
    • Author(s)
      中木戸誠、津本浩平
    • Publisher
      朝倉書店(印刷中)
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Book] 遺伝子工学2011
    • Author(s)
      津本浩平
    • Publisher
      化学同人
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Book] 生物工学2011
    • Author(s)
      津本浩平
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Book] Amino Acids, Peptides and Proteins in Organic Chemistry Volume 5-Analysis and Function of Amino Acids and Peptides2011
    • Author(s)
      Satoshi Ohtake, Yoshiko Kita, Kouhei Tsumoto, Tsutomu Arakawa
    • Publisher
      Wiley
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Book] BIOINDUSTRY2011
    • Author(s)
      津本浩平
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Book] 抗体の安定性向上技術2011
    • Author(s)
      津本浩平
    • Publisher
      BIOINDUSTRY
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Book] 生化学事典2011
    • Author(s)
      中木戸誠、津本浩平
    • Publisher
      朝倉書店
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Book] タンパク質相互作用解析:等温滴定型熱量測定と表面プラズモン共鳴2011
    • Author(s)
      津本浩平
    • Publisher
      生物工学
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Book] ファインケミカルシリーズ抗体医薬のための細胞構築と培養技術2010
    • Author(s)
      津本浩平、江島大輔、荒川力
    • Publisher
      シーエムシー出版
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Book] 酵素:一般論「酵素利用技術大系」2010
    • Author(s)
      津本浩平
    • Publisher
      株式会社エヌ・ティーエス
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Book] 酵素利用技術大系2010
    • Author(s)
      津本浩平
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Book] 抗原抗体相互作用の熱力学的制御生体機能関連化学部会ニュースレター2010
    • Author(s)
      津本浩平
    • Publisher
      社団法人日本化学会
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Book] 抗体会合体の定量的評価の課題抗体医薬のための細胞構築と培養技術2010
    • Author(s)
      津本浩平、江島大輔、荒川力
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Book] リフォールディング「酵素利用技術大系」2010
    • Author(s)
      工藤基徳、津本浩平
    • Publisher
      株式会社エヌ・ティーエス
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Book] Encyclopedia of Life Sciences2010
    • Author(s)
      Kumagai I. and Tsumoto K.
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Book] 薬学雑誌2009
    • Author(s)
      津本浩平、宇井美穂子
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Book] 熱測定2009
    • Author(s)
      津本浩平、宇井美穂子
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Book] たんぱく質結晶の新展開2008
    • Author(s)
      津本、田中
    • Publisher
      シーエムシー出版(印刷中)
    • Data Source
      KAKENHI-PROJECT-19021011

  • [Book] たんぱく質結晶の新展開2008
    • Author(s)
      津本、田中
    • Total Pages
      15
    • Publisher
      シーエムシー出版
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Book] たんぱく質結晶の新展開2008
    • Author(s)
      津本, 田中
    • Publisher
      シーエムシー出版
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Book] ナノバイオ辞典2007
    • Author(s)
      津本 浩平 (分担執筆)
    • Total Pages
      1000
    • Publisher
      エヌティーエス
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Book] ナノバイオ辞典2007
    • Author(s)
      津本 浩平(分担執筆)
    • Total Pages
      1000
    • Publisher
      エヌティーエス
    • Data Source
      KAKENHI-PROJECT-18038007

  • [Book] バイオプロダクション2006
    • Author(s)
      津本 浩平
    • Total Pages
      250
    • Publisher
      コロナ社
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Book] バイオプロダクション2006
    • Author(s)
      津本 浩平(分担執筆)
    • Total Pages
      180
    • Publisher
      コロナ社
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Book] 生物物理学ハンドブック(分担執筆)2006
    • Author(s)
      津本 浩平
    • Total Pages
      500
    • Publisher
      朝倉書店
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Book] バイオプロダクション2006
    • Author(s)
      津本
    • Total Pages
      20
    • Publisher
      コロナ社
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Book] 生物物理学ハンドブック2006
    • Author(s)
      津本, ら
    • Total Pages
      4
    • Publisher
      朝倉書店
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Book] ナノバイオ辞典2006
    • Author(s)
      津本
    • Total Pages
      2
    • Publisher
      テクノシステム
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Book] 生物物理学ハンドブック(分担執筆)2006
    • Author(s)
      津本 浩平
    • Total Pages
      500
    • Publisher
      朝倉書店
    • Data Source
      KAKENHI-PROJECT-18038007

  • [Book] バイオプロダクション2006
    • Author(s)
      津本 浩平(分担執筆)
    • Total Pages
      180
    • Publisher
      コロナ社
    • Data Source
      KAKENHI-PROJECT-18038007

  • [Book] ゲノミクス・プロテオミクスの新展開~生物情報の解析と応用~2005
    • Author(s)
      津本
    • Total Pages
      10
    • Publisher
      エヌ・ティー・エス
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Book] コンビナトリアルバイオエンジニアリングの展開 (担当部分)ファージディスプレイの現状と今後:プロテオミクスと蛋白質工学2004
    • Author(s)
      津本浩平ら
    • Publisher
      CMC社(印刷中)
    • Data Source
      KAKENHI-PROJECT-16041204

  • [Book] コンビナトリアルバイオエンジニアリングの展開 (担当部分)ファージディスプレイの現状と今後:プロテオミクスと蛋白質工学2004
    • Author(s)
      津本浩平ら
    • Publisher
      CMC社(印刷中)
    • Data Source
      KAKENHI-PROJECT-14704006

  • [Book] コンビナトリアルバイオエンジニアリングの展開(担当部分)ファージディスプレイの現状と今後:プロテオミクスと蛋白質工学2004
    • Author(s)
      津本浩平ら
    • Publisher
      CMC社(印刷中)
    • Data Source
      KAKENHI-PROJECT-16106011

  • [Journal Article] How the protonation state of a phosphorylated amino acid governs molecular recognition: insights from classical molecular dynamics simulations2020
    • Author(s)
      Kawade Raiji、Kuroda Daisuke、Tsumoto Kouhei
    • Journal Title

      FEBS LETTERS

      Volume: 594 Pages: 903-912

    • DOI

      10.1002/1873-3468.13674

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05766, KAKENHI-PROJECT-19H03522, KAKENHI-PROJECT-19H04202, KAKENHI-PROJECT-19J14494

  • [Journal Article] Generation of biparatopic antibody through two-step targeting of fragment antibodies on antigen using SpyTag and SpyCatcher2020
    • Author(s)
      Akiba Hiroki、Takayanagi Kensuke、Kusano-Arai Osamu、Iwanari Hiroko、Hamakubo Takao、Tsumoto Kouhei
    • Journal Title

      Biotechnology Reports

      Volume: 25

    • DOI

      10.1016/j.btre.2020.e00418

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19H05766

  • [Journal Article] Engineering Stability, Viscosity, and Immunogenicity of Antibodies by Computational Design2020
    • Author(s)
      Kuroda Daisuke、Tsumoto Kouhei
    • Journal Title

      Journal of Pharmaceutical Sciences

      Volume: 109 Pages: 1631-1651

    • DOI

      10.1016/j.xphs.2020.01.011

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-19H05766, KAKENHI-PROJECT-19H03522, KAKENHI-PROJECT-19H04202

  • [Journal Article] Structural and thermodynamic basis for the recognition of the substrate-binding cleft on hen egg lysozyme by a single-domain antibody2019
    • Author(s)
      Akiba Hiroki、Tamura Hiroko、Kiyoshi Masato、Yanaka Saeko、Sugase Kenji、Caaveiro Jose M. M.、Tsumoto Kouhei
    • Journal Title

      Scientific Reports

      Volume: 9 Pages: 15481-15481

    • DOI

      10.1038/s41598-019-50722-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-19H05766, KAKENHI-PROJECT-18K14892

  • [Journal Article] Phospholipid Membrane Fluidity Alters Ligand Binding Activity of a G Protein-Coupled Receptor by Shifting the Conformational Equilibrium2019
    • Author(s)
      Yoshida K, Nagatoishi S, Kuroda D, Suzuki N, Murata T, Tsumoto K.
    • Journal Title

      Biochemistry

      Volume: 58(6) Pages: 504-508

    • DOI

      10.1021/acs.biochem.8b01194

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-18H02082

  • [Journal Article] Computer-guided library generation applied to the optimization of single-domain antibodies2019
    • Author(s)
      Akiba Hiroki、Tamura Hiroko、Caaveiro Jose M M、Tsumoto Kouhei
    • Journal Title

      Protein Engineering, Design and Selection

      Volume: 32 Pages: 423-431

    • DOI

      10.1093/protein/gzaa006

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19H05766

  • [Journal Article] Design strategy for serine hydroxymethyltransferase probes based on retro-aldol-type reaction2019
    • Author(s)
      Nonaka H, Nakanishi Y, Kuno S, Ota T, Mochidome K, Saito Y, Sugihara F, Takakusagi Y, Aoki I, Nagatoishi S, Tsumoto K, Sando S.
    • Journal Title

      Nature Communications

      Volume: 10(1) Pages: 876-876

    • DOI

      10.1038/s41467-019-08833-7

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-18H02082

  • [Journal Article] Biophysical characterization of the breast cancer-related BIG3-PHB2 interaction: Effect of non-conserved loop region of BIG3 on the structure and the interaction2019
    • Author(s)
      Chigira T, Nagatoishi S, Takeda H, Yoshimaru T, Katagiri T, Tsumoto K.
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 518 Pages: 183-189

    • DOI

      10.1016/j.bbrc.2019.08.028

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-17H06419, KAKENHI-PLANNED-19H05766, KAKENHI-PROJECT-18H02082, KAKENHI-PROJECT-17K10551

  • [Journal Article] Structural features of methionine aminopeptidase2-active core peptide essential for binding with S100A42019
    • Author(s)
      Katagiri Naohiro、Nagatoishi Satoru、Tsumoto Kouhei、Endo Hideya
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 516 Pages: 1123-1129

    • DOI

      10.1016/j.bbrc.2019.07.006

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19H05766, KAKENHI-PROJECT-18H02082

  • [Journal Article] Exploring designability of electrostatic complementarity at an antigen-antibody interface directed by mutagenesis, biophysical analysis, and molecular dynamics simulations2019
    • Author(s)
      Yoshida K, Kuroda D, Kiyoshi M, Nakakido M, Nagatoishi S, Soga S, Shirai H, Tsumoto K.
    • Journal Title

      Scientific Reports

      Volume: 9(1) Pages: 4482-4482

    • DOI

      10.1038/s41598-019-40461-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-18H02082

  • [Journal Article] Generation and Characterization of Antagonistic Anti-Human Interleukin (IL)-18 Monoclonal Antibodies with High Affinity : Two Types of Monoclonal Antibodies Against Full-Length IL-18 and the Neoepitope of Inflammatory Caspase-Cleaved Active IL-18.2019
    • Author(s)
      Yuko Nariai, Hiroki Kamino, Eiji Obayashi, Hiroaki Kato, Gyosuke Sakashita, Tomoko Sugiura, Kiyoshi Migita, Tomohiro Koga, Atsushi Kawakami, Kazuma Sakamoto, Kenji Kadomatsu, Makoto Nakakido, Kouhei Tsumoto and Takeshi Urano
    • Journal Title

      Archives of Biochemistry and Biophysics

      Volume: 663 Pages: 71-82

    • DOI

      10.1016/j.abb.2019.01.001

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08983, KAKENHI-PROJECT-18K05556, KAKENHI-PROJECT-18K06086, KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-16H05139, KAKENHI-PROJECT-19H00340

  • [Journal Article] Affinity Improvement of a Cancer-Targeted Antibody through Alanine-Induced Adjustment of Antigen-Antibody Interface.2019
    • Author(s)
      Yamashita Takefumi、Mizohata Eiichi、Nagatoishi Satoru、Watanabe Takahiro、Nakakido Makoto、Iwanari Hiroko、Mochizuki Yasuhiro、Nakayama Taisuke、Kado Yuji、Yokota Yuki、Matsumura Hiroyoshi、Kawamura Takeshi、Kodama Tatsuhiko、Hamakubo Takao、Inoue Tsuyoshi、Fujitani Hideaki、Tsumoto Kouhei
    • Journal Title

      Structure

      Volume: 27 Pages: 519-527

    • DOI

      10.1016/j.str.2018.11.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K06094, KAKENHI-PUBLICLY-17H05732, KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-18H02082

  • [Journal Article] Long-Term Stability and Reversible Thermal Unfolding of Antibody Structure at Low pH: Case Study2018
    • Author(s)
      Fukada H, Tsumoto K, Arakawa T, Ejima D.
    • Journal Title

      Journal of Pharmaceutical Sciences

      Volume: 107 Pages: 2965-2967

    • DOI

      10.1016/j.xphs.2018.07.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Journal Article] Inhibition of homophilic dimerization and disruption of cell adhesion by P-cadherin-specific small molecules from SPR-based assays2018
    • Author(s)
      Senoo A, Nagatoishi S, Moberg A, Babol LN, Mitani T, Tashima T, Kudo S, Tsumoto K.
    • Journal Title

      Chemical Communications

      Volume: 54 Pages: 5350-5353

    • DOI

      10.1039/c8cc01964a

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-18H02082, KAKENHI-PLANNED-18H05425

  • [Journal Article] Production and characterization of a novel site-specific-modifiable anti-OX40-receptor single-chain variable fragment for targeted drug delivery2018
    • Author(s)
      Tanabe A, Nakano K, Nakakido M, Nagatoishi S, Tanaka Y, Tsumoto K, Uchimaru K, Watanabe T.
    • Journal Title

      Biophys. Biochem. Res. Commun.

      Volume: 496 Pages: 614-620

    • DOI

      10.1016/j.bbrc.2018.01.051

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-16H06693

  • [Journal Article] Assessing the heterogeneity of the Fc-glycan of a therapeutic antibody using an engineered FcγReceptor IIIa-immobilized column2018
    • Author(s)
      Kiyoshi M, Caaveiro JMM, Tada M, Tamura H, Tanaka T, Terao Y, Morante K, Harazono A, Hashii N, Shibata H, Kuroda D, Nagatoishi S, Oe S, Ide T, Tsumoto K, Ishii-Watabe A
    • Journal Title

      Sci. Rep.

      Volume: 8:3955 Pages: 1-11

    • DOI

      10.1038/s41598-018-22199-8

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K18113, KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-15K06962

  • [Journal Article] A combination of 19 F NMR and surface plasmon resonance for site-specific hit selection and validation of fragment molecules that bind to the ATP-binding site of a kinase2018
    • Author(s)
      Nagatoishi S, Yamaguchi S, Katoh E, Kajita K, Yokotagawa T, Kanai S, Furuya T, Tsumoto K.
    • Journal Title

      Bioorganic & Medicinal Chemistry

      Volume: 26 Pages: 1929-1938

    • DOI

      10.1016/j.bmc.2018.02.041

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-18H02082

  • [Journal Article] 12. Improvement of antibody affinity by introduction of basic amino acid residues into the framework region.2018
    • Author(s)
      Fukunaga A, Maeta S, Reema B, Nakakido M, Tsumoto K.
    • Journal Title

      Biochem Biophys Rep.

      Volume: 15 Pages: 81-85

    • DOI

      10.1016/j.bbrep.2018.07.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Journal Article] Tyrosine Sulfation Restricts the Conformational Ensemble of a Flexible Peptide, Strengthening the Binding Affinity for an Antibody2018
    • Author(s)
      K. Miyanabe, T. Yamashita, Y. Abe, H. Akiba, Y. Takamatsu, M. Nakakido, T. Hamakubo, T. Ueda, JMM. Caaveiro, and K. Tsumoto
    • Journal Title

      Biochemistry

      Volume: 57 Pages: 4177-4185

    • DOI

      10.1021/acs.biochem.8b00592

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15KT0103, KAKENHI-PROJECT-15H05752, KAKENHI-PROJECT-16H02420

  • [Journal Article] A secondary RET mutation in the activation loop conferring resistance to vandetanib2018
    • Author(s)
      Nakaoku T, Kohno T, Araki M, Niho S, Chauhan R, Knowles PP, Tsuchihara K, Matsumoto S, Shimada Y, Mimaki S, Ishii G, Ichikawa H, Nagatoishi S, Tsumoto K, Okuno Y, Yoh K, McDonald NQ, Goto K.
    • Journal Title

      Nature Communications

      Volume: 9 Pages: 625-625

    • DOI

      10.1038/s41467-018-02994-7

    • NAID

      120006406830

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-17K15036

  • [Journal Article] PRDM14 directly interacts with heat shock proteins HSP90α and GRP78.2018
    • Author(s)
      Moriya C, Taniguchi H, Nagatoishi S, Igarashi H, Tsumoto K, Imai K
    • Journal Title

      Cancer Science

      Volume: 109 Pages: 373-383

    • DOI

      10.1111/cas.13458

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-16H04710

  • [Journal Article] Enzymatically cleavable traceless biotin tags for protein PEGylation and purification.2018
    • Author(s)
      Adam Marcin Wawro, Yusuke Aoki, Takahiro Muraoka, Kouhei Tsumoto, and Kazushi Kinbara
    • Journal Title

      Chem. Commun.

      Volume: 印刷中 Pages: 1913-1916

    • DOI

      10.1039/c7cc05814d

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-17H05147, KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-17H04885

  • [Journal Article] Repertoire Analysis of Antibody CDR-H3 Loops Suggests Affinity Maturation Does Not Typically Result in Rigidification.2018
    • Author(s)
      Jeliazkov JR, Sljoka A, Kuroda D, Tsuchimura N, Katoh N, Tsumoto K, Gray JJ
    • Journal Title

      Front. Immunol.

      Volume: 9:413 Pages: 1-17

    • DOI

      10.3389/fimmu.2018.00413

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K18113, KAKENHI-PROJECT-16H02420

  • [Journal Article] Development of drug discovery screening system by molecular interaction kinetics-mass spectrometry2018
    • Author(s)
      Obi N, Fukuda T, Nakayama N, Ervin J, Bando Y, Nishimura T, Nagatoishi S, Tsumoto K, Kawamura T.
    • Journal Title

      Rapid Communications in Mass Spectrometry

      Volume: 32 Pages: 665-671

    • DOI

      10.1002/rcm.8083

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-18H02082

  • [Journal Article] Biophysical Analysis of the Protein-Small Molecule Interactions to Develop Small Molecule Drug Discovery2018
    • Author(s)
      Nagatoishi S, Caaveiro JMM, Tsumoto K.
    • Journal Title

      薬学雑誌

      Volume: 138(8) Issue: 8 Pages: 1033-1041

    • DOI

      10.1248/yakushi.17-00211-2

    • NAID

      130007429352

    • ISSN
      0031-6903, 1347-5231
    • Language
      Japanese
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-18H02082

  • [Journal Article] Antibody Affinity Maturation by Computational Design.2018
    • Author(s)
      Kuroda D, Tsumoto K.
    • Journal Title

      Methods Mol Biol.

      Volume: 1827 Pages: 15-34

    • DOI

      10.1007/978-1-4939-8648-4_2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Journal Article] Thermodynamic and computational analyses reveal the functional roles of the galloyl group of tea catechins in molecular recognition2018
    • Author(s)
      Takahashi T, Nagatoishi S, Kuroda D, Tsumoto K.
    • Journal Title

      PLOS ONE

      Volume: 13(10)

    • DOI

      10.1371/journal.pone.0204856

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-18H02082

  • [Journal Article] Structures of the prefusion form of measles virus fusion protein in complex with inhibitors.2018
    • Author(s)
      Hashiguchi T, Fukuda Y, Matsuoka R, Kuroda D, Kubota M, Shirogane Y, Watanabe S, Tsumoto K, Kohda D, Plemper RK, Yanagi Y
    • Journal Title

      Proc. Natl. Acad. Sci. U. S. A.

      Volume: 115(10) Pages: 2496-2501

    • DOI

      10.1073/pnas.1718957115

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K18113, KAKENHI-PROJECT-16H02420

  • [Journal Article] Synergistic cytotoxic effect on gastric cancer cells of an immunotoxin cocktail in which antibodies recognize different epitopes on CDH17.2018
    • Author(s)
      Kusano-Arai O, Iwanari H, Kudo S, Akiba H, Matsusaka K, Kaneda A, Fukayama M, Tsumoto K, Hamakubo T.
    • Journal Title

      Monoclon Antib Immunodiagn Immunother

      Volume: 37 Pages: 1-11

    • DOI

      10.1089/mab.2017.0043

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K08729, KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-26253021, KAKENHI-PROJECT-16H05412

  • [Journal Article] Glycaemic control boosts glucosylated nanocarrier crossing the BBB into the brain.2018
    • Author(s)
      Y. Anraku, H. Kuwahara, Y. Fukusato, A. Mizoguchi, T. Ishii, K. Nitta, Y. Matsumoto, K. Toh, K. Miyata, S. Uchida, K. Nishina, K. Osada, K. Itaka, N. Nishiyama, H. Mizusawa, T. Yamasoba, T. Yokota, K. Kataoka
    • Journal Title

      Nat. Commun.

      Volume: 8 Pages: 1-001

    • DOI

      10.1038/s41467-017-00952-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17KT0048, KAKENHI-PROJECT-16K11226, KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-15H04635, KAKENHI-PROJECT-15H04813, KAKENHI-PROJECT-16H03178, KAKENHI-PROJECT-17H04742, KAKENHI-PROJECT-16F16058, KAKENHI-PROJECT-16F16407, KAKENHI-PROJECT-16K15104, KAKENHI-PROJECT-15K20962, KAKENHI-PROJECT-25000006

  • [Journal Article] Significance of a histone-like protein with its native structure for the diagnosis of asymptomatic tuberculosis.2018
    • Author(s)
      Ohara Yukiko、Ozeki Yuriko、Tateishi Yoshitaka、Mashima Tsukasa、Arisaka Fumio、Tsunaka Yasuo、Fujiwara Yoshie、Nishiyama Akihito、Yoshida Yutaka、Kitadokoro Kengo、Kobayashi Haruka、Kaneko Yukihiro、Nakagawa Ichiro、Maekura Ryoji、Yamamoto Saburo、Katahira Masato、Matsumoto Sohkichi
    • Journal Title

      PLoS One

      Volume: 13 Pages: 0204160-0204160

    • DOI

      10.1371/journal.pone.0204160

    • NAID

      120006534592

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K07269, KAKENHI-PROJECT-18K08172, KAKENHI-PROJECT-16H05187, KAKENHI-PROJECT-16H05188, KAKENHI-PROJECT-16K14048, KAKENHI-PROJECT-17K19552

  • [Journal Article] Characterization of glycoengineered anti-HER2 monoclonal antibodies produced by using a silkworm baculovirus expression system2018
    • Author(s)
      Egashira Y, Nagatoishi S, Kiyoshi M, Ishii-Watabe A, Tsumoto K.
    • Journal Title

      The Journal of Biochemistry

      Volume: 163 Pages: 481-488

    • DOI

      10.1093/jb/mvy021

    • NAID

      40021579952

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-18H02082

  • [Journal Article] Structural behavior of keratin-associated protein 8.1 in human hair as revealed by a monoclonal antibody.2018
    • Author(s)
      Akiba H, Ikeuchi E, Ganbat J, Fujikawa H, Arai-Kusano O, Iwanari H, Nakakido M, Hamakubo T, Shimomura Y, Tsumoto K.
    • Journal Title

      J Struct Biol.

      Volume: 204(2) Pages: 207-214

    • DOI

      10.1016/j.jsb.2018.08.011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Journal Article] Intramolecular H-bonds govern the recognition of a flexible peptide by an antibody2018
    • Author(s)
      Miyanabe, K., Akiba, H., Kuroda, D., Nakakido, M., Kusano-Arai, O., Iwanari, H., Hamakubo, T., Caaveiro, J.M.M., and Tsumoto, K.
    • Journal Title

      The Journal of Biochemistry

      Volume: in press Pages: 65-76

    • DOI

      10.1093/jb/mvy032

    • NAID

      40021625331

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K06962, KAKENHI-PROJECT-16H02420

  • [Journal Article] Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1.2018
    • Author(s)
      Tashiro, S. Caaveiro, J. Nakakido, M. Tanabe, A. Nagatoishi, S. Tamura, Y. Matsuda, N. Liu, D.
    • Journal Title

      ACS. Chem. Biol.

      Volume: 13 Pages: 2783-2793

    • DOI

      10.1021/acschembio.8b00701

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-17H06414, KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-18H02082, KAKENHI-PROJECT-18H02443, KAKENHI-PROJECT-17J07322, KAKENHI-PROJECT-17K19338, KAKENHI-PROJECT-15H05705

  • [Journal Article] Enhanced intracellular delivery of siRNA by controlling ATP-responsivity of phenylboronic acid-functionalized polyion complex micelles.2018
    • Author(s)
      M. Naito, N. Yoshinaga, T. Ishii, A. Matsumoto, Y. Miyahara, K. Miyata, K. Kataoka
    • Journal Title

      Macromol. Biosci.

      Volume: 1

    • DOI

      10.1002/mabi.201700357

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25000006

  • [Journal Article] Weak electrostatic interactions between collagen and monomeric SLRP osteomodulin govern the shape of type I collagen fibrils2018
    • Author(s)
      Takumi Tashima , Satoru Nagatoishi, Jose M.M. Caaveiro, Makoto Nakakido, Hiroshi Sagara, Osamu Kusano-Arai, Hiroko Iwanari, Hitomi Mimuro, Takao Hamakubo, Shin-ichi Ohnuma and Kouhei Tsumoto
    • Journal Title

      Commun Biol

      Volume: 1:33 Pages: 1-10

    • DOI

      10.1038/s42003-018-0038-2

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17J10207, KAKENHI-PROJECT-15K06962, KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-18H02082, KAKENHI-PROJECT-17K19551, KAKENHI-PLANNED-18H05425

  • [Journal Article] Roles of the disulfide bond between the variable and the constant domains of rabbit immunoglobulin kappa chains in thermal stability and affinity2018
    • Author(s)
      Kawade R, Akiba H, Entzminger K, Maruyama T, Okumura CJ, Tsumoto K.
    • Journal Title

      Protein Engineering, Design and Selection

      Volume: 31 Pages: 243-247

    • DOI

      10.1093/protein/gzy008

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Journal Article] Use of SpyTag/SpyCatcher to construct bispecific antibodies that target two epitopes of a single antigen.2017
    • Author(s)
      K. Yumura, H. Akiba, S. Nagatoishi, O. Kusano-Arai, H. Iwanari, T. Hamakubo, K. Tsumoto
    • Journal Title

      J. Biochem.

      Volume: 162 Pages: 203-210

    • DOI

      10.1093/jb/mvx023

    • NAID

      40021326109

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-25000006

  • [Journal Article] Biophysical characterization of the interaction between heme and proteins responsible for heme transfer in Streptococcus pyogenes2017
    • Author(s)
      Hoshino M, Nakakido M, Nagatoishi S, Aikawa C, Nakagawa I, Tsumoto K.
    • Journal Title

      Biophys. Biochem. Res. Commun.

      Volume: 493 Pages: 1109-1114

    • DOI

      10.1016/j.bbrc.2017.09.055

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08775, KAKENHI-PROJECT-17K19552, KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-16H04710, KAKENHI-PROJECT-16H05188, KAKENHI-PROJECT-16H06693

  • [Journal Article] Insight in the Evolution of Therapeutic Monoclonal Antibodies<br/>&mdash;Fundamental Technologies for Creation and Evaluation of Next Generation mAbs&mdash;2017
    • Author(s)
      Ishii-Watabe A, Tsumoto K.
    • Journal Title

      薬学雑誌

      Volume: 137 Issue: 7 Pages: 815-816

    • DOI

      10.1248/yakushi.16-00252-f

      10.1248/yakushi.16-00252-F

    • NAID

      130007287840

    • ISSN
      0031-6903, 1347-5231
    • Language
      Japanese
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Journal Article] Improved Brain Expression of Anti-Amyloid β scFv by Complexation of mRNA Including a Secretion Sequence with PEG-based Block Catiomer.2017
    • Author(s)
      F. Perche, S. Uchida, H. Akiba, C. -Y. Lin, M. Ikegami, A. Dirisala, T. Nakashima, K. Itaka, K. Tsumoto, K. Kataoka
    • Journal Title

      Curr. Alzheimer Res.

      Volume: 14 Pages: 295-302

    • DOI

      10.2174/1567205013666161108110031

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K20962, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-16H02420

  • [Journal Article] Elucidation of potential sites for antibody engineering by fluctuation editing.2017
    • Author(s)
      Yanaka Saeko、Moriwaki Yoshitaka、Tsumoto Kouhei、Sugase Kenji
    • Journal Title

      Sci. Rep.

      Volume: 7 Pages: 9597-9597

    • DOI

      10.1038/s41598-017-10246-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-17H05893, KAKENHI-PROJECT-16H02420

  • [Journal Article] Analysis of Pore Formation and Protein Translocation Using Large Biological Nanopores2017
    • Author(s)
      Watanabe H, Gubbiotti A, Chinappi M, Takai N, Tanaka K, Tsumoto K and Kawano R
    • Journal Title

      Analytical Chemistry

      Volume: 89 Pages: 11269-11277

    • DOI

      10.1021/acs.analchem.7b01550

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-16H06043

  • [Journal Article] Disruption of cell adhesion by an antibody targeting the cell-adhesive intermediate (X-dimer) of human P-cadherin.2017
    • Author(s)
      Kudo S, Caaveiro JM, Nagatoishi S, Miyafusa T, Matsuura T, Sudou Y, Tsumoto K.
    • Journal Title

      Scientific Reports

      Volume: 7 Pages: 39518-39518

    • DOI

      10.1038/srep39518

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K17882, KAKENHI-PROJECT-15K06962, KAKENHI-PROJECT-24000011

  • [Journal Article] Polymeric SpyCatcher Scaffold Enables Bioconjugation in a Ratio-Controllable Manner.2017
    • Author(s)
      Jia L, Minamihata K, Ichinose H, Tsumoto K and Kamiya N
    • Journal Title

      Biotechnol. J.

      Volume: 12 Pages: 1700195-1700195

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Journal Article] Production and characterization of genetically modified human IL-11 variants.2017
    • Author(s)
      Sano E, Takei T, Ueda T, Tsumoto K.
    • Journal Title

      Biochim Biophys Acta.

      Volume: 1861 Pages: 205-217

    • DOI

      10.1016/j.bbagen.2016.11.028

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Journal Article] Therapeutic vesicular nanoreactors with tumor-specific activation and self-destruction for synergistic tumor ablation.2017
    • Author(s)
      J. Li, A. Dirisala, Z. Ge, Y. Wang, W. Yin, W. Ke, K. Toh, J. Xie, Y. Matsumoto, Y. Anraku, K. Osada, K. Kataoka
    • Journal Title

      Angew. Chem. Int. Ed.

      Volume: 56 Pages: 14025-14030

    • DOI

      10.1002/anie.201706964

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17KT0048, KAKENHI-PROJECT-16K11226, KAKENHI-PROJECT-16H03178, KAKENHI-PROJECT-15K12536, KAKENHI-PROJECT-25000006

  • [Journal Article] Through-bond effects in the ternary complexes of thrombin sandwiched by two DNA aptamers.2017
    • Author(s)
      A. Pica, I. R. Krauss, V. Parente, H. Tateishi-Karimata, S. Nagatoishi, K. Tsumoto, N. Sugimoto, and F. Sica
    • Journal Title

      Nucleic Acids Res.

      Volume: 45 Pages: 461-469

    • DOI

      10.1093/nar/gkw1113

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02283, KAKENHI-PROJECT-15K17882, KAKENHI-PROJECT-26810094, KAKENHI-PROJECT-16H02420

  • [Journal Article] Adhesive Dimerization of Human P-Cadherin Catalyzed by a Chaperone-like Mechanism2017
    • Author(s)
      Kudo S, Caaveiro JM, Tsumoto K.
    • Journal Title

      Structure

      Volume: 24 Pages: 1523-1526

    • DOI

      10.1016/j.str.2016.07.002

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K06962, KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-16H02420

  • [Journal Article] Structural basis for binding and transfer of heme in bacterial heme-acquisition systems.2017
    • Author(s)
      Naoe Youichi、Nakamura Nozomi、Rahman Md. Mahfuzur、Tosha Takehiko、Nagatoishi Satoru、Tsumoto Kouhei、Shiro Yoshitsugu、Sugimoto Hiroshi
    • Journal Title

      Proteins

      Volume: 85 Pages: 2217-2230

    • DOI

      10.1002/prot.25386

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-17H05896, KAKENHI-PROJECT-26220807, KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-16H04710, KAKENHI-PROJECT-17H03092

  • [Journal Article] Functional contacts between MPER and the anti-HIV-1 broadly neutralizing antibody 4E10 extend into the core of the membrane.2017
    • Author(s)
      Rujas, E., Insausti, S., Garcia-Porras, M., Sanchez-Eugenia, R., Tsumoto, K., Nieva, J.L., and Caaveiro, J.M.M.
    • Journal Title

      Journal of Molecular Biology

      Volume: 429 Pages: 1213-1226

    • DOI

      10.1016/j.jmb.2017.03.008

    • NAID

      120006328970

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K06962, KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-16H02420

  • [Journal Article] Peripheral Membrane Interactions Boost the Engagement by an Anti HIV-1 Broadly Neutralizing Antibody.2017
    • Author(s)
      Rujas E, Caaveiro JM, Insausti S, Garcia-Porras M, Tsumoto K, Nieva JL
    • Journal Title

      Journal of Biological Chemistry

      Volume: 292 Pages: 5571-5583

    • DOI

      10.1074/jbc.m117.775429

    • NAID

      120006328971

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K06962, KAKENHI-PROJECT-24000011

  • [Journal Article] Structure of the triose-phosphate/phosphate translocator reveals the basis of substrate specificity2017
    • Author(s)
      Lee Y, Nishizawa T, Takemoto M, Kumazaki K, Yamashita K, Hirata K, Minoda A, Nagatoishi S, Tsumoto K, Ishitani R and Nureki O.
    • Journal Title

      Nat. Plants.

      Volume: 3 Pages: 825-832

    • DOI

      10.1038/s41477-017-0022-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-16H04710, KAKENHI-PROJECT-17H03640, KAKENHI-PROJECT-15J08129, KAKENHI-PROJECT-16J07405, KAKENHI-PROJECT-16H06294, KAKENHI-PROJECT-17H05000

  • [Journal Article] Thermodynamic analyses of amino acid residues at the interface of an antibody B2212A and its antigen roundabout homolog 12017
    • Author(s)
      A. Yui, H. Akiba, S. Kudo, M. Nakakido, S. Nagatoishi, K. Tsumoto
    • Journal Title

      J. Biochem.

      Volume: 162 Pages: 255-258

    • DOI

      10.1093/jb/mvx050

    • NAID

      40021380511

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-16H04710, KAKENHI-PROJECT-16H06693, KAKENHI-PROJECT-25000006

  • [Journal Article] Polyplex micelle installing intracellular self-processing functionalities without free catiomers for safe and efficient systemic gene therapy through tumor vasculature targeting.2017
    • Author(s)
      Q. Chen, K. Osada, Z. Ge, S. Uchida, T. A. Tockary, A. Dirisala, A. Matsui, K. Toh, K. M. Takeda, X. Liu, T. Nomoto, T. Ishii, M. Oba, Y. Matsumoto, K. Kataoka
    • Journal Title

      Biomaterials

      Volume: 113 Pages: 253-265

    • DOI

      10.1016/j.biomaterials.2016.10.042

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-14J11005, KAKENHI-PROJECT-15K20962, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-17KT0048, KAKENHI-PROJECT-16K11226, KAKENHI-PROJECT-16H03178

  • [Journal Article] Hemolytic actinoporins interact with carbohydrates using their lipid-binding module2017
    • Author(s)
      Tanaka K, Caaveiro JMM, Morante K and Tsumoto K.
    • Journal Title

      Philos. Trans. R. Soc. Lond. B Biol. Sci.

      Volume: 372 Pages: 20160216-20160216

    • DOI

      10.1098/rstb.2016.0216

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-15K06962

  • [Journal Article] Mitochonic Acid 5 Binds Mitochondria and Ameliorates Renal Tubular and Cardiac Myocyte Damage.2016
    • Author(s)
      Suzuki T, Nagatoishi S, Tsumoto K, Abe T. (全41人，5番目と25番目)
    • Journal Title

      J Am Soc Nephrol

      Volume: 印刷中

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25249115

  • [Journal Article] Targeted systemic delivery of siRNA to cervical cancer model using cyclic RGD-installed unimer polyion complex-assembled gold nanoparticles.2016
    • Author(s)
      Y. Yi, H. -J. Kim, P. Mi, M. Zheng, H. Takemoto, K. Toh, B. -S. Kim, K. Hayashi, M. Naito, Y. Matsumoto, K. Miyata, K. Kataoka
    • Journal Title

      Journal of Controlled Release

      Volume: 244 Pages: 247-256

    • DOI

      10.1016/j.jconrel.2016.08.041

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11226, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25282141

  • [Journal Article] Mitochonic acid MA-5 binds to mitochondria and ameliorates renal tubular and cardiac myocyte damages.2016
    • Author(s)
      Suzuki T, Kanno SI, Abe T. et al
    • Journal Title

      J. Am. Soc. Nephrol.

      Volume: 27 Pages: 1925-1932

    • DOI

      10.1681/asn.2015060623

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26340020, KAKENHI-PROJECT-26860094, KAKENHI-PROJECT-15H06367, KAKENHI-PROJECT-16H04678, KAKENHI-PROJECT-16H04710, KAKENHI-PROJECT-26282153, KAKENHI-PROJECT-26460331, KAKENHI-PROJECT-15K17882, KAKENHI-PROJECT-16K12925, KAKENHI-PROJECT-16K14719, KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-26293031, KAKENHI-PROJECT-26305007

  • [Journal Article] Identification of a Mebrane-bound Prepore Species Clarifies the Lytic Mechanism of Actinoporins.2016
    • Author(s)
      Morante, K., Bellomio, A., Gil-Carton, D., Redondo-Morata, L., Sot, J., Scheuring, S., Valle, M., Gonzalez-Manas, J.M., Tsumoto, K., and Caaveiro, J.M.M.
    • Journal Title

      J Biol Chem.

      Volume: 291 Pages: 19210-19219

    • DOI

      10.1074/jbc.m116.734053

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K06962, KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-16H02420

  • [Journal Article] Epiregulin recognition mechanisms by anti-epiregulin antibody 9E5: Structural, functional and molecular dynamics simulation analyses2016
    • Author(s)
      Kado Y1, Mizohata E2, Nagatoishi S3, Iijima M4, Shinoda K4, Miyafusa T3, Nakayama T2, Yoshizumi T2, Sugiyama A4, Kawamura T4, Lee YH4, Matsumura H2, Doi H4, Fujitani H4, Kodama T4, Shibasaki Y4, Tsumoto K5, Inoue T6.
    • Journal Title

      J. Biol. Chem.

      Volume: 291 Pages: 2319-2330

    • DOI

      10.1074/jbc.m115.656009

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670377, KAKENHI-PROJECT-15K17882, KAKENHI-PLANNED-24109017, KAKENHI-PROJECT-25249115, KAKENHI-PROJECT-25440022, KAKENHI-PROJECT-25282230, KAKENHI-PUBLICLY-26102526

  • [Journal Article] Assessment of the Protein-Protein Interactions in a Highly Concentrated Antibody Solution by Using Raman Spectroscopy2016
    • Author(s)
      Ota C, Noguchi S, Nagatoishi S, Tsumoto K.
    • Journal Title

      Pharm Res.

      Volume: 33(4) Pages: 956-969

    • DOI

      10.1007/s11095-015-1842-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25249115, KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-16H02420

  • [Journal Article] Differential Effect of Membrane Composition on the Pore-Forming Ability of Four Different Sea Anemone Actinoporins.2016
    • Author(s)
      Garcia-Linares, S., Rivera-de-Torre, E., Morante, K., Tsumoto, K., Caaveiro, J.M.M., Gavilanes, J.G., Slotte, J.P., and Martinez-del-Pozo, A.
    • Journal Title

      Biochemistry

      Volume: 55 Pages: 6630-6641

    • DOI

      10.1021/acs.biochem.6b01007

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K06962, KAKENHI-PROJECT-16H02420

  • [Journal Article] Integrative Network Analysis Combined with Quantitative Phosphoproteomics Reveals TGFBR2 as a Novel Regulator of Glioblastoma Stem Cell Properties.2016
    • Author(s)
      Narushima Y, Kozuka-Hata H, Koyama-Nasu R, Tsumoto K, Inoue J, Akiyama T & Oyama M.
    • Journal Title

      Mol. Cell. Proteomics

      Volume: 15 Pages: 1017-1031

    • DOI

      10.1074/mcp.m115.049999

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K06838, KAKENHI-PROJECT-26505001, KAKENHI-PLANNED-22117002, KAKENHI-PUBLICLY-15H01176, KAKENHI-ORGANIZER-22117001, KAKENHI-PROJECT-25249115, KAKENHI-PROJECT-26290036

  • [Journal Article] In-Cell Enzymology To Probe His-Heme Ligation in Heme Oxygenase Catalysis.2016
    • Author(s)
      Sigala PA, Morante K, Tsumoto K, Caaveiro JM, Goldberg DE.
    • Journal Title

      Biochemistry

      Volume: 55 Pages: 4836-4849

    • DOI

      10.1021/acs.biochem.6b00562

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Journal Article] Quantitative phosphoproteomics-based molecular network description for high-resolution kinase-substrate interactome analysis2016
    • Author(s)
      Narushima, Y., Kozuka-Hata, H., Tsumoto, K., Inoue, J. and Oyama, M.
    • Journal Title

      Bioinformatics.

      Volume: 印刷中 Pages: 2083-2088

    • DOI

      10.1093/bioinformatics/btw164

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-22117002, KAKENHI-PUBLICLY-15H01176, KAKENHI-ORGANIZER-22117001, KAKENHI-PROJECT-25249115, KAKENHI-PROJECT-26290036, KAKENHI-PLANNED-16H06575, KAKENHI-PLANNED-16H06578, KAKENHI-PROJECT-26505001, KAKENHI-PROJECT-16H02420

  • [Journal Article] Structural basis for broad neutralization of HIV-1 through the molecular recognition of 10E8 helical epitope at the membrane interface.2016
    • Author(s)
      Rujas, E., Caaveiro, J.M.M., Partida-Hanon, A., Gulzar, N., Morante, K., Apellaniz, B., Garcia-Porras, M., Bruix, M., Tsumoto, K., Scott, J.K., Jimenez, M.A., and Nieva, J.L.
    • Journal Title

      Sci Rep.

      Volume: 6 Pages: 38177-38177

    • DOI

      10.1038/srep38177

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K06962, KAKENHI-PROJECT-16H02420

  • [Journal Article] Reply to "The Broadly Neutralizing, Anti-HIV Antibody 4E10: an Open and Shut Case?"2016
    • Author(s)
      Rujas E, Gulzar N, Morante K, Tsumoto K, Scott JK, Nieva JL, Caaveiro JM
    • Journal Title

      J. Virol.

      Volume: 90(6) Pages: 3276-3277

    • DOI

      10.1128/jvi.02970-15

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25249115

  • [Journal Article] Structural basis for binding of human IgGl to its high-affinity human receptor FcgRI.2016
    • Author(s)
      M. Kiyoshi, JM. Caaveiro, T. Kawai, S. Tashiro, T. Ide, Y. Asaoka, K. Hatayama, K. Tsumoto
    • Journal Title

      Nat. Commun.

      Volume: 6 Pages: 6866-6866

    • DOI

      10.1038/ncomms7866

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25249115, KAKENHI-PROJECT-14J08172, KAKENHI-PROJECT-25000006

  • [Journal Article] Structural basis for amino acid export by DMT superfamily transporter YddG.2016
    • Author(s)
      H. Tsuchiya, S. Doki, M. Takemoto, T. Ikuta, T. Higuchi, K. Fukui, Y. Usuda, E. Tabuchi, S. Nagatoishi, K. Tsumoto, T. Nishizawa, K. Ito, N. Dohmae, R. Ishitani and O. Nureki
    • Journal Title

      Nature

      Volume: 534 Pages: 417-420

    • DOI

      10.1038/nature17991

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24227004, KAKENHI-PROJECT-16H04710, KAKENHI-PROJECT-15J08129, KAKENHI-PROJECT-25291011, KAKENHI-PROJECT-26410190, KAKENHI-PROJECT-15K17882, KAKENHI-PROJECT-16H06294, KAKENHI-PROJECT-16H02420

  • [Journal Article] pH responsiveness of fibrous assemblies of repeat-sequence amphipathic α-helix polypeptides.2015
    • Author(s)
      Takei T, Tsumoto K, Okonogi A, Kimura A, Kojima S, Yazaki K, Takei T, Ueda T, Miura K.
    • Journal Title

      Protein Sci.

      Volume: 24(5) Pages: 883-894

    • DOI

      10.1002/pro.2665

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25249115

  • [Journal Article] Bidirectional Transformation of a Metamorphic Protein between the Water-Soluble and Transmembrane Native States2015
    • Author(s)
      Koji Tanaka, Jose M. M. Caaveiro, Kouhei Tsumoto
    • Journal Title

      Biochemistry

      Volume: 54 Pages: 6863-6866

    • DOI

      10.1021/acs.biochem.5b01112

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K06962, KAKENHI-PROJECT-25249115, KAKENHI-PROJECT-14J07513, KAKENHI-PROJECT-24000011

  • [Journal Article] Thermodynamics of antibody-antigen interaction revealed by mutation analysis of antibody variable regions2015
    • Author(s)
      Hiroki Akiba, Kouhei Tsumoto
    • Journal Title

      The Journal of Biochemistry

      Volume: 158(1) Pages: 1-13

    • DOI

      10.1093/jb/mvv049

    • NAID

      40020522493

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25249115, KAKENHI-PROJECT-24000011

  • [Journal Article] Differential binding of prohibitin-2 to estrogen receptor α and to drugresistant ER α mutants2015
    • Author(s)
      Takeru Chigira, Satoru Nagatoishi, Kouhei Tsumoto
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 463 Pages: 726-731

    • DOI

      10.1016/j.bbrc.2015.06.002

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K17882, KAKENHI-PROJECT-25249115, KAKENHI-PROJECT-24000011

  • [Journal Article] Differential Effects of IFN-β on the Survival and Growth of Human Vascular Smooth Muscle and Endothelial Cells.2015
    • Author(s)
      Sano E, Tashiro S, Tsumoto K, Ueda T.
    • Journal Title

      Biores Open Access.

      Volume: 4(1) Pages: 1-15

    • DOI

      10.1089/biores.2014.0052

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25249115, KAKENHI-PROJECT-14J08172

  • [Journal Article] Structural basis for inhibition of the Tob-CNOT7 interaction by a fragment screening approach.2015
    • Author(s)
      Bai Y, Tashiro S, Nagatoishi S, Suzuki T, Yan D, Liu R, Tsumoto K, Bartlam M, Yamamoto T.
    • Journal Title

      Protein Cell.

      Volume: 6 Pages: 924-928

    • DOI

      10.1007/s13238-015-0225-6

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K17882, KAKENHI-PROJECT-25249115, KAKENHI-PROJECT-14J08172

  • [Journal Article] Discovery and characterization of natural tropolones as inhibitors of the antibacterial target CapF from Staphylococcus aureus.2015
    • Author(s)
      Nakano K, Chigira T, Miyafusa T, Nagatoishi S, Caaveiro JM, Tsumoto K.
    • Journal Title

      Sci. Rep.

      Volume: 5 Pages: 15337-15337

    • DOI

      10.1038/srep15337

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K17882, KAKENHI-PROJECT-25249115

  • [Journal Article] Osteomodulin regulates diameter and alters shape of collagen fibrils.2015
    • Author(s)
      Tashima T, Nagatoishi S, Sagara H, Ohnuma S, Tsumoto K.
    • Journal Title

      Biochem. Biophys. Res. Commun.

      Volume: 463 Pages: 292-296

    • DOI

      10.1016/j.bbrc.2015.05.053

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K17882, KAKENHI-PROJECT-25249115

  • [Journal Article] A Pore-Forming Toxin Requires a Specific Residue for Its Activity in Membranes with Particular Physicochemical properties2015
    • Author(s)
      Koldo Morante, Jose M.M. Caaveiro, Koji Tanaka, Juan Manuel Gonzalez-Manas and Kouhei Tsumoto
    • Journal Title

      J. Biol. Chem.

      Volume: M114 Pages: 10850-10861

    • DOI

      10.1074/jbc.m114.615211

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-14J07513, KAKENHI-PROJECT-25249115

  • [Journal Article] Rapid Heme Transfer Reactions between NEAr Transporter Domains of Staphylococcus aureus: A Theoretical Study Using QM/MM and MD Simulations.2015
    • Author(s)
      Moriwaki Y, Terada T, Tsumoto K, Shimizu K.
    • Journal Title

      PLoS One

      Volume: 10(12)

    • DOI

      10.1371/journal.pone.0145125

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25249115

  • [Journal Article] Structural Analysis of Fc/Fc_R Complexes : A Blueprint for Antibody Design.2015
    • Author(s)
      JM. Caaveiro, M. Kiyoshi, K. Tsumoto
    • Journal Title

      Immunol. Rev.

      Volume: 268 Pages: 201-221

    • DOI

      10.1111/imr.12365

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K06962, KAKENHI-PROJECT-25249115, KAKENHI-PROJECT-25000006

  • [Journal Article] The Atomic Structure of the HIV-1 gp41 Transmembrane Domain and Its Connection to the Immunogenic Membrane-proximal External Region2015
    • Author(s)
      Apellaniz B, Rujas E, Serrano S, Morante K, Tsumoto K, Caaveiro JM, Jimenez MA, Nieva JL.
    • Journal Title

      J. Biol. Chem.

      Volume: 290 (21) Pages: 12999-13015

    • DOI

      10.1074/jbc.m115.644351

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25249115

  • [Journal Article] Structural features of interfacial tyrosine residue in ROBO1 fibronectin domain-antibody complex: Crystallographic, thermodynamic, and molecular dynamic analyses.2015
    • Author(s)
      Nakayama T, Mizohata E, Yamashita T, Nagatoishi S, Nakakido M, Iwanari H, Mochizuki Y, Kado Y, Yokota Y, Satoh R, Tsumoto K, Fujitani H, Kodama T, Hamakubo T, Inoue T.
    • Journal Title

      Protein Science

      Volume: 24 Pages: 328-340

    • DOI

      10.1002/pro.2619

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-24108007, KAKENHI-PROJECT-25220205

  • [Journal Article] Structural basis for self-assembly of a cytolytic pore lined by protein and lipid.2015
    • Author(s)
      Koji Tanaka, Jose M.M. Caaveiro, Koldo Morante, Juan Manuel Gonzalez-Manas and Kouhei Tsumoto
    • Journal Title

      Nat Commun.

      Volume: 6 Pages: 6337-6337

    • DOI

      10.1038/ncomms7337

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-14J07513, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25249115

  • [Journal Article] Protein stabilization by an amphiphilic short monodisperse oligo(ethylene glycol).2015
    • Author(s)
      Nabanita Sadhukhan, Takahiro Muraoka, Mihoko Ui, Satoru Nagatoishi, Kouhei Tsumoto, Kazushi Kinbara
    • Journal Title

      Chemical communications (Cambridge, England)

      Volume: 51 Pages: 8457-8460

    • DOI

      10.1039/c4cc10301g

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26410170, KAKENHI-PROJECT-25249115, KAKENHI-PROJECT-25410166

  • [Journal Article] Functional characterization of Val60, a key residue in the membrane-oligomerization of fragaceatoxin C, an Actinoporin from Actinia fragacea2015
    • Author(s)
      Morante K, Caaveiro JM, Viguera AR, Tsumoto K, Gonzalez-Manas JM
    • Journal Title

      FEBS Lett.

      Volume: 589(15) Pages: 1840-1846

    • DOI

      10.1016/j.febslet.2015.06.012

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25249115

  • [Journal Article] Structural and thermodynamics basis of epitope binding to neutralizing and non-neutralizing forms of the anti-HIV-1 4E10 antibody2015
    • Author(s)
      Rujas, E., Gulzar, N., Morante, K., Tsumoto, K., Scott, J.K., Nieva, J.L. and Caaveiro, J.M.M.
    • Journal Title

      J. Virol.

      Volume: 89 Pages: 11975-11991

    • DOI

      10.1128/jvi.01793-15

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K06962, KAKENHI-PROJECT-25249115

  • [Journal Article] Thermodynamic characterization of the interaction between the human Y-box binding protein YB-1 and nucleic acids2015
    • Author(s)
      Yumiko Tanabe, Satoru Nagatoishi, Kouhei Tsumoto
    • Journal Title

      Molecular BioSystems

      Volume: 11 Pages: 2441-2448

    • DOI

      10.1039/c5mb00184f

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25249115, KAKENHI-PROJECT-24000011

  • [Journal Article] Reversible ion transportation switch by a ligand-gated synthetic supramolecular ion channel.2014
    • Author(s)
      Takahiro Muraoka, Takahiro Endo, Kazuhito V. Tabata, Hiroyuki Noji, Satoru Nagatoishi, Kouhei Tsumoto, Rui Li and Kazushi Kinbara
    • Journal Title

      J Am Chem Soc.

      Volume: 136 Pages: 15584-15595

    • DOI

      10.1021/ja5070312

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-23115003, KAKENHI-PROJECT-25249115

  • [Journal Article] Role of positions e and g in the fibrous assembly formation of an amphipathic α-helix-forming polypeptide.2014
    • Author(s)
      Takei, T.
    • Journal Title

      Biopolymers

      Volume: in press Pages: 260-272

    • DOI

      10.1002/bip.22479

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23247013, KAKENHI-PROJECT-23570190, KAKENHI-PROJECT-25249115

  • [Journal Article] Precise engineering of siRNA delivery vehicles to tumors using polygon complexes and gold nanoparticles2014
    • Author(s)
      H. -J. Kim, H. Takemoto, Y. Yi, M. Zheng, Y. Maeda, H. Chaya, K. Hayashi, P. Mi, F. Pittella, R. J. Christie, K. Toh, Y. Matsumoto, N. Nishiyama, K. Miyata, K. Kataoka
    • Journal Title

      ACS Nano

      Volume: 8 Pages: 8979-8991

    • DOI

      10.1021/nn502125h

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-13F03349, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25282141, KAKENHI-PROJECT-26670738

  • [Journal Article] Heme Binding Mechanism of Structurally Similar Iron-Regulated Surface Determinant Near Transporter Domains of Staphylococcus aureus Exhibiting Different Affinities for Heme2014
    • Author(s)
      Yoshitaka Moriwaki
    • Journal Title

      Biochemistry

      Volume: 52 Pages: 8866-8877

    • DOI

      10.1021/bi4008325

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-13J06526, KAKENHI-PROJECT-23300109, KAKENHI-PROJECT-24000011, KAKENHI-PUBLICLY-24102516, KAKENHI-PROJECT-25249115, KAKENHI-PROJECT-25708026

  • [Journal Article] Affinity improvement of a therapeutic antibody by structure-based computational design : generation of electrostatic interactions in the transition state stabilizes the antibody-antigen complex.2014
    • Author(s)
      Masato Kiyoshi, Jose M.M. Caaveiro, Eri Miura, Satoru Nagatoishi, Makoto Nakakido, Shinji Soga, Hiroki Shirai, Shigeki Kawabata, Kouhei Tsumoto
    • Journal Title

      PLoS One

      Volume: 9

    • DOI

      10.1371/journal.pone.0087099

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-24750166, KAKENHI-PROJECT-25000006

  • [Journal Article] Targeted gene delivery by polyplex micelles with crowded PEG palisade and cRGD moiety for systemic treatment of pancreatic tumors.2014
    • Author(s)
      Z. Ge, Q. Chen, K. Osada, X. Liu, T. A. Tockary, S. Uchida, A. Dirisala, T. Ishii, T. Nomoto, K. Toh, Y. Matsumoto, M. Oba, M. R. Kano, K. Itaka, K. Kataoka
    • Journal Title

      Biomaterials.

      Volume: 35 Pages: 3416-3426

    • DOI

      10.1016/j.biomaterials.2013.12.086

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-23790043, KAKENHI-PROJECT-23790433, KAKENHI-PROJECT-24300170, KAKENHI-PROJECT-24790530, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25882011, KAKENHI-PROJECT-26293119, KAKENHI-PROJECT-26670738

  • [Journal Article] Actively-targeted polygon complex micelles stabilized by cholesterol and disulfide cross-linking for systemic delivery of siRNA to solid tumors2014
    • Author(s)
      Y. Oe, R. J. Christie, M. Naito, S. A. Low, S. Fukushima, K. Toh, Y. Miura, Y. Matsumoto, N. Nishiyama, K. Miyata, K. Kataoka
    • Journal Title

      Biomaterials

      Volume: 35 Pages: 7887-7895

    • DOI

      10.1016/j.biomaterials.2014.05.041

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-24659584, KAKENHI-PROJECT-24689051, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25282141, KAKENHI-PROJECT-26670738

  • [Journal Article] Alternative downstream processes for production of antibodies and antibody fragments2014
    • Author(s)
      Tsutomu Arakawa, Kouhei Tsumoto, Daisuke Ejima
    • Journal Title

      Biochimica et Biophysica Acta - Proteins and Proteomics

      Volume: 1844 Pages: 2032-2040

    • DOI

      10.1016/j.bbapap.2014.05.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24000011

  • [Journal Article] Multifunctional polyion complex micelle featuring enhanced stability, targetability, and endosome escapability for systemic siRNA delivery to subcutaneous model of lung cancer.2014
    • Author(s)
      Hyun Jin Kim, Takehiko Ishii, Meng Zheng, Sumiyo Watanabe, Kazuko Toh, Yu Matsumoto, Nobuhiro Nishiyama, Kanjiro Miyata, Kazunori Kataoka
    • Journal Title

      Drug Deliv. Transl.Res.

      Volume: 4 Pages: 50-60

    • DOI

      10.1007/s13346-013-0175-6

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-13F03349, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-23790043, KAKENHI-PROJECT-24659411, KAKENHI-PROJECT-24790530, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25282141, KAKENHI-PROJECT-26670738

  • [Journal Article] Identification and characterization of the X-dimer of human P-cadherin: Implications for homophilic cell adhesion2014
    • Author(s)
      Shota Kudo, Jose M. M. Caaveiro, Shuichiro Goda, Satoru Nagatoishi, Keisuke Ishii, Tadashi Matsuura, Yukio Sudou, Tatsuhiko Kodama, Takao Hamakubo, and Kouhei Tsumoto
    • Journal Title

      Biochemistry

      Volume: 53(11) Pages: 1742-1752

    • DOI

      10.1021/bi401341g

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-13J04678, KAKENHI-PROJECT-24000011, KAKENHI-PLANNED-24108007, KAKENHI-PROJECT-24750166, KAKENHI-PROJECT-25220205, KAKENHI-PROJECT-25450133

  • [Journal Article] The staphylococcal elastin-binding protein regulates zinc-dependent growth/biofilm formation2014
    • Author(s)
      M. Nakakido, C. Aikawa, I. Nakagawa, K. Tsumoto.
    • Journal Title

      The journal of Biochemistry

      Volume: 156 Pages: 155-162

    • DOI

      10.1093/jb/mvu027

    • NAID

      40020192566

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-12J06919, KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-25000006, KAKENHI-PUBLICLY-25125708, KAKENHI-PROJECT-25249115, KAKENHI-PROJECT-25293370, KAKENHI-PROJECT-26860285

  • [Journal Article] Grafting synthetic transmembrane units to the engineered low-toxicity α-hemolysin to restore its hemolytic activity.2014
    • Author(s)
      Mihoko Ui, Kousuke Harima, Toshiaki Takei, Kouhei Tsumoto, Kazuhito V. Tabata, Hiroyuki Noji, Sumire Endo, Kimio Akiyama, Takahiro Muraoka, and Kazushi Kinbara
    • Journal Title

      Molecular bioSystems.

      Volume: 10 Pages: 3199-3206

    • DOI

      10.1039/c4mb00405a

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-23115003, KAKENHI-PROJECT-25249115, KAKENHI-PROJECT-25410166

  • [Journal Article] Three-layered polyplex micelle as a multifunctional nanocarrier platform for light-induced systemic gene transfer.2014
    • Author(s)
      T. Nomoto, S. Fukushima, M. Kumagai, K. Machitani, Arnida, Y. Matsumoto, M. Oba, K. Miyata, K. Osada, N. Nishiyama, K. Kataoka
    • Journal Title

      Nat Commun

      Volume: 5 Pages: 1-10

    • DOI

      10.1038/ncomms4545

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-11J08266, KAKENHI-PROJECT-13F03042, KAKENHI-PROJECT-14J11005, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-23790043, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25670010

  • [Journal Article] Peptide-dependent conformational fluctuation determines the stability of the human leukocyte antigen class I complex2014
    • Author(s)
      Saeko Yanaka, Takamasa Ueno, Yi Shi, Jianxun Gi, George F. Gao, Kouhei Tsumoto, and Kenji Sugase
    • Journal Title

      J Biol, Chem.

      Volume: 268 Pages: 24680-24690

    • DOI

      10.1074/jbc.m114.566174

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-13J09564, KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-24390254, KAKENHI-PROJECT-25000006, KAKENHI-PUBLICLY-25133706, KAKENHI-PROJECT-25249115

  • [Journal Article] Thermodynamic and Structural Characterization of the Specific Binding of Zn(II) to Human Protein DJ-1.2014
    • Author(s)
      Shinya Tashiro, Jose M. M. Caaveiro, Chun-Xiang Wu, Quyen Q. Hoang, Kouhei Tsumoto
    • Journal Title

      FEBS Lett.

      Volume: 53(14) Pages: 2218-2220

    • DOI

      10.1021/bi500294h

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-14J08172, KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25249115

  • [Journal Article] Protective effect of the long pentraxin PTX3 against histone-mediated endothelial cell cytotoxicity in sepsis2014
    • Author(s)
      Daigo K, Nakakido M, Ohashi R, Fukuda R, Matsubara K, Minami T, Yamaguchi N, Inoue K, Jiang S, Naito M, Tsumoto K, Hamakubo T.
    • Journal Title

      Sci signal

      Volume: 7

    • DOI

      10.1126/scisignal.2005522

    • NAID

      120005537769

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-24108007, KAKENHI-PROJECT-24591070, KAKENHI-PROJECT-25220205, KAKENHI-PROJECT-26290035, KAKENHI-PROJECT-26640069

  • [Journal Article] Bidirectional binding property of high glycine-tyrosine keratin-associated protein contributes to the mechanical strength and shape of hair.2013
    • Author(s)
      Ryo Matsunaga, Ryota Abe, Daisuke Ishii, Shun-ichi Watanabe, Masato Kiyoshi, Bernd Nöcker, Masaru Tsuchiya, Kouhei Tsumoto
    • Journal Title

      J Struct Biol.

      Volume: 183 Pages: 484-494

    • DOI

      10.1016/j.jsb.2013.06.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-13J05539, KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-25249115

  • [Journal Article] Crystal Structure of Enzyme CapF of Staphylococcus aureus Reveals a Unique Architecture Composed of Two Functional Domains.2013
    • Author(s)
      Miyafusa T, Caaveiro JM, Tanaka Y, Tsumoto K
    • Journal Title

      Biochem J.

      Volume: (印刷中) Pages: 671-680

    • DOI

      10.1042/bj20112049

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-09J07066, KAKENHI-PROJECT-21360398, KAKENHI-PROJECT-24655145

  • [Journal Article] Dynamic elements govern the catalytic activity of CapE, a capsular polysaccharide-synthesizing enzyme from Staphylococcus aureus2013
    • Author(s)
      Takamitsu Miyafusa, Jose M. M. Caaveiro, Yoshikazu Tanaka, Kouhei Tsumoto
    • Journal Title

      FEBS Letters

      Volume: 587 Pages: 3824-3830

    • DOI

      10.1016/j.febslet.2013.10.009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24000011

  • [Journal Article] Hyperthin nanochains composed of self-polymerizing protein shackles.2013
    • Author(s)
      Ryo Matsunaga, Saeko Yanaka, Satoru Nagatoishi, Kouhei Tsumoto
    • Journal Title

      Nat Commun.

      Volume: 4 Pages: 2211-2211

    • DOI

      10.1038/ncomms3211

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-13J05539, KAKENHI-PROJECT-13J09564, KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-24750166, KAKENHI-PROJECT-25249115

  • [Journal Article] Crystal structure of the capsular polysaccharide synthesizing protein CapE of Staphylococcus aureus.2013
    • Author(s)
      Takamitsu Miyafusa, Jose M. M. Caaveiro, Yoshikazu Tanaka, Martin E. Tanner, Kouhei Tsumoto
    • Journal Title

      Biosci. Rep.

      Volume: 33 Pages: 2155-2159

    • DOI

      10.1042/bsr20130017

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-25249115

  • [Journal Article] Tethered PEG crowdedness determining shape and blood circulation profile of polyplex micelle gene carriers.2013
    • Author(s)
      Theofilus A. Tockary, Kensuke Osada, Qixian Chen, Kaori Machitani, Anjaneyulu Dirisala, Satoshi Uchida, Takahiro Nomoto, Kazuko Toh, Yu Matsumoto, Keiji Itaka, Koji Nitta, Kuniaki Nagayama, and Kazunori Kataoka
    • Journal Title

      Macromolecules

      Volume: 46 Pages: 6585-6592

    • DOI

      10.1021/ma401093z

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24300170, KAKENHI-PROJECT-24790530, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25882011

  • [Journal Article] Selective binding of antimicrobial porphyrins to the heme-receptor IsdH-NEAT3 of Staphylococcus aureus2013
    • Author(s)
      Nhuan Vu
    • Journal Title

      Protein Sci.

      Volume: 22 Pages: 942-953

    • DOI

      10.1002/pro.2276

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-13J06526, KAKENHI-PROJECT-23300109, KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-25249115

  • [Journal Article] Effects of subclass change on the structural stability of chimeric, humanized, and human antibodies under thermal stress2013
    • Author(s)
      Takahiko Ito, Kouhei Tsumoto
    • Journal Title

      Protein Science

      Volume: 22 Pages: 1542-1551

    • DOI

      10.1002/pro.2340

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24000011

  • [Journal Article] Directed Evolution and Structural Analysis of NADPH-Dependent Acetoacetyl Coenzyme A (Acetoacetyl-CoA) Reductase from Ralstonia eutropha Reveals Two Mutations Responsible for Enhanced Kinetics2013
    • Author(s)
      Ken'ichiro Matsumoto, Yoshikazu Tanaka, Tsuyoshi Watanabe, Ren Motohashi, Koji Ikeda, Kota Tobitani, Min Yao, Isao Tanaka, Seiichi Taguchi
    • Journal Title

      Applied and Environmental Microbiology

      Volume: 79 Pages: 6134-6139

    • DOI

      10.1128/aem.01768-13

    • NAID

      120005411137

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24000011

  • [Journal Article] Heme Degradation by Staphylococcus aureus IsdG and IsdI Liberates Formaldehyde Rather Than Carbon Monoxide2013
    • Author(s)
      Matsui T, Nambu S, Ono Y, Goulding CW, Tsumoto K, Ikeda-Saito M.
    • Journal Title

      Biochemistry

      Volume: 52 Pages: 3025-3027

    • DOI

      10.1021/bi400382p

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24000011, KAKENHI-ORGANIZER-24120001, KAKENHI-PLANNED-24120006, KAKENHI-PROJECT-24350081, KAKENHI-PUBLICLY-25109504

  • [Journal Article] Effects of chain length of an amphipathic polypeptide carrying the repeated amino acid sequence (LETLAKA)(n) on α-helix and fibrous assembly formation.2013
    • Author(s)
      Takei T., et al
    • Journal Title

      Biochemistry

      Volume: 52 Pages: 2810-2820

    • DOI

      10.1021/bi400001c

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21227006, KAKENHI-PROJECT-23247013, KAKENHI-PROJECT-25249115

  • [Journal Article] Improving the affinity of an antibody for its antigen via long-range electrostatic interactions2013
    • Author(s)
      Atsushi Fukunaga, Kouhei Tsumoto
    • Journal Title

      Protein Engineering Design & Selection

      Volume: 26 Pages: 773-780

    • DOI

      10.1093/protein/gzt053

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24000011

  • [Journal Article] Establishment of a microcarrier culture system with serial sub-cultivation for functionally active human endothelial cells2012
    • Author(s)
      Tashiro S, Tsumoto K, Sano E
    • Journal Title

      J.Biotechnol.

      Volume: (印刷中)

    • DOI

      10.1016/j.jbiotec.2012.02.022

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Journal Article] Mapping ultra-weak protein-protein interactions between heme transporters of Staphylococcus aureus.2012
    • Author(s)
      Ryota Abe, Jose M.M.Caaveiro, Hiroko Kozuka-Hata, Masaaki Oyama, Kouhei Tsumoto
    • Journal Title

      J Biol Chem

      Volume: (印刷中) Pages: 16477-16487

    • DOI

      10.1074/jbc.m112.346700

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J06068, KAKENHI-PROJECT-21360398, KAKENHI-PROJECT-23510254

  • [Journal Article] Interleukin- 11 links oxidative stress and compensatory proliferation2012
    • Author(s)
      Nishina T, Komazawa-Sakon S, Yanaka S, Zheng X, Palo J, Kojima Y, Yamashina S, Sano E, Putoczki T, Doi T, Ueno T, Ezaki J, Ushio H, Ernst M, Kouhei T, Okamura K, Nakano H
    • Journal Title

      Science Signaling

      Volume: 5

    • DOI

      10.1126/scisignal.2002056

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J06193, KAKENHI-PROJECT-21360398, KAKENHI-PROJECT-23390260, KAKENHI-PROJECT-23659404, KAKENHI-PROJECT-24390100, KAKENHI-PROJECT-24700705, KAKENHI-PROJECT-24790328, KAKENHI-PUBLICLY-23117717

  • [Journal Article] Catalytic activity of MsbA reconstituted in nanodisc particles is modulated by remote interactions with the bilayer2011
    • Author(s)
      Kawai T, Caaveiro JM, Abe R, Katagiri T, Tsumoto K
    • Journal Title

      FEBS Lett

      Volume: 585 Pages: 3533-3537

    • DOI

      10.1016/j.febslet.2011.10.015

    • Data Source
      KAKENHI-PROJECT-21360398

  • [Journal Article] Refolding single-chain antibody (scFv) using lauroyl-L-glutamate as a solubilization detergent and arginine as a refolding additive2011
    • Author(s)
      Motonori Kudou ; Daisuke Ejima ; Haruna Sato ; Ryosuke Yumioka ; Tsutomu Arakawa ; and Kouhei Tsumoto
    • Journal Title

      Protein Exp.Purif.

      Volume: 77 Pages: 68-74

    • DOI

      10.1016/j.pep.2010.12.007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Journal Article] A novel protein refolding system using lauroyl-l-glutamate as a solubilizing detergent and arginine as a folding assisting agent2011
    • Author(s)
      Kudou M, Yumioka R, Ejima D, Arakawa T, Tsumoto K
    • Journal Title

      Protein Expr Purif

      Volume: 75 Pages: 46-54

    • DOI

      10.1016/j.pep.2010.08.011

    • Data Source
      KAKENHI-PROJECT-21360398

  • [Journal Article] Gene expression profiling predicts response to temozolomide in malignant gliomas.2011
    • Author(s)
      Yoshino A, Ogino A, Yachi K, Ohta T, Fukushima T, Watanabe T, Katayama Y, Okamoto Y, Naruse N, Sano E, Tsumoto K.
    • Journal Title

      Int J Oncol.

      Volume: 36(6) Pages: 1367-1377

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Journal Article] Chemical and Pharmacological Chaperones : Application for Recombinant Protein Production and Protein Folding Diseases2011
    • Author(s)
      Rahul S. Rajan, Kouhei Tsumoto, Masao Tokunaga, Hiroko Tokunaga, Yoshiko Kita and Tsutomu Arakawa
    • Journal Title

      Current Medicinal Chemistry

      Volume: 18 Pages: 1-15

    • DOI

      10.2174/092986711793979698

    • Data Source
      KAKENHI-PROJECT-21360398

  • [Journal Article] Hydration is required in DNA G-quadruplex-protein binding2011
    • Author(s)
      Nagatoishi S, Isono N, Tsumoto K, Sugimoto N
    • Journal Title

      ChemBioChem

      Volume: 12 Pages: 1822-1826

    • DOI

      10.1002/cbic.201100264

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21360398, KAKENHI-PROJECT-22655057

  • [Journal Article] A novel protein refolding system using lauroy1-1-glutamate as a solubilizing detergent and arginine as a folding assisting agent.2011
    • Author(s)
      Kudou M, Yumioka R, Ejima D, Arakawa T, Tsumoto K.
    • Journal Title

      Protein Exp.Purif.

      Volume: 印刷中掲載確定

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Journal Article] Chemical and Pharmacological Chaperones : Application for Recombinant Protein Production and Protein Folding Diseases.2011
    • Author(s)
      Rajan R S, Tsumoto K, Tokunaga M, Tokunaga H, Kita Y, Arakawa T
    • Journal Title

      Current Medicinal Chemistry

      Volume: 18(1) Pages: 11-15

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Journal Article] Stepwise Characterization of the Thermodynamics of Trichocyte Intermediate Filament Protein Supramolecular Assembly2011
    • Author(s)
      Ishii D, Abe R, Watanabe SI, Tsuchiya M, Nocker B, Tsumoto K
    • Journal Title

      J. Mol. Biol

      Volume: 408 Pages: 832-838

    • DOI

      10.1016/j.jmb.2011.03.034

    • Data Source
      KAKENHI-PROJECT-21360398

  • [Journal Article] Gene expression profiles predicting the response to IFN-β and a combination of temozolomide and IFN-β in malignant gliomas2011
    • Author(s)
      Yoshino A, Tashiro S, Ogino A, Yachi K, Ohta T, Fukushima T, Watanabe T, Katayama Y, Okamoto Y, Sano E, Tsumoto K
    • Journal Title

      Int J Oncol.

      Volume: 39 Pages: 529-542

    • DOI

      10.3892/ijo.2011.1068

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Journal Article] Molecular Basis of Recognition of Antibacterial Porphyrins by Heme-Transporter IsdH-NEAT3 of Staphylococcus aureus2011
    • Author(s)
      Moriwaki Y, Caaveiro JM, Tanaka Y, Tsutsumi H, Hamachi I, Tsumoto K
    • Journal Title

      Biochemistry

      Volume: 50 Pages: 7311-7320

    • DOI

      10.1021/bi200493h

    • Data Source
      KAKENHI-PROJECT-21360398

  • [Journal Article] Non-core region modulates interleukin-11 signaling activity : Generation of agonist and antagonist variants2011
    • Author(s)
      Yanaka S, Sano E, Naruse N, Miura KI, Futatsumori-Sugai M, Caaveiro JM, Tsumoto K
    • Journal Title

      J. Biol. Chem

      Volume: 286 Pages: 8085-8093

    • DOI

      10.1074/jbc.m110.152561

    • Data Source
      KAKENHI-PROJECT-21360398

  • [Journal Article] Monoubiquitination of Tob/BTG family proteins competes with degradation-targeting polyubiquitination2011
    • Author(s)
      Suzuki T
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 409 Pages: 70-4

    • DOI

      10.1016/j.bbrc.2011.04.107

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229006, KAKENHI-PROJECT-21360398, KAKENHI-PUBLICLY-23121506, KAKENHI-PROJECT-23510254, KAKENHI-PROJECT-23689027

  • [Journal Article] Refolding single-chain antibody (scFv) using lauroyl-L-glutamate as a solubilization detergent and arginine as a refolding additive.2011
    • Author(s)
      Kudou M, Ejima D, Sato H, Yumioka R, Arakawa T, Tsumoto K
    • Journal Title

      Protein Exp.Purif.

      Volume: 印刷中掲載確定

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Journal Article] Structural and Energetic Hot-Spots for the Interaction between a Ladder-like Polycyclic Ether and the Anti-Ciguatoxin Antibody 10C9Fab2011
    • Author(s)
      Mihoko Ui, Yoshikazu Tanaka, Takeshi Tsumuraya, Ikuo Fujii, Masayuki Inoue, Masahiro Hirama, Kouhei Tsumoto
    • Journal Title

      Molecular BioSystems

      Volume: 7 Pages: 793-798

    • DOI

      10.1039/c0mb00162g

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Journal Article] Structural and Energetic Hot-Spots for the Interaction between a Ladder-like Polycyclic Ether and the Anti-Ciguatoxin Antibody 10C9Fab2011
    • Author(s)
      Mihoko Ui, Yoshikazu Tanaka, Takeshi Tsumuraya, Ikuo Fujii, Masayuki Inoue, Masahiro Hirama, and Kouhei Tsumoto
    • Journal Title

      Molecular Bio Systems

      Volume: 7 Pages: 793-798

    • Data Source
      KAKENHI-PROJECT-21360398

  • [Journal Article] Molecular basis of recognition of antibacterial porphyrions by heme-transoprter IsdH-NEAT3 of Staphylococcus aureus Biochemistry2011
    • Author(s)
      Moriwaki, Y., Caaveiro, J.M.M., Tanaka, Y., Tsutsumi, H., Hamachi, I., Tsumoto, K.
    • Journal Title

      Biochemistry

      Volume: 50 Pages: 7211-7320

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Journal Article] Non-core region modulates interleukin-11 signaling activity : Generation of agonist and antagonist variants.2011
    • Author(s)
      Yanaka S, Sano E, Naruse N, More KI, Futatsumori-Sugai M, Caaveiro JM, Tsumoto K
    • Journal Title

      J.Biol.Chem.

      Volume: 印刷中掲載確定

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Journal Article] Structural and Energetic Hot-Spots for the Interaction between a Ladde r-like Polycychc Ether and the Anti-Ciguatoxin Antibody 10C9Fab.2011
    • Author(s)
      Ui M, Tanaka Y, Tsumuraya T, Fujii I, Inoue M, Hirama M, Tsumoto K
    • Journal Title

      Mol.BioSyst.

      Volume: 印刷中掲載確定

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Journal Article] Contribution of asparagine residues to the stabilization of a proteinaceous antigen-antibody complex : HyHEL-10-HEL2010
    • Author(s)
      Yokota A., Tsumoto K., Shiroishi M., Nakanishi T., Kondo H., Kumagai I
    • Journal Title

      J. Biol. Chem

      Volume: 285 Pages: 7686-7696

    • DOI

      10.1074/jbc.m109.089623

    • Data Source
      KAKENHI-PROJECT-21360398

  • [Journal Article] Temperature and salt concentration alter base-sequence selectivity of a duplex DNA-binding protein2010
    • Author(s)
      Nagatoishi S, Tanaka Y, Kudou M and Tsumoto K
    • Journal Title

      Mol. Biosyst

      Volume: 6 Pages: 98-101

    • DOI

      10.1039/b914828k

    • Data Source
      KAKENHI-PROJECT-21360398

  • [Journal Article] An approach to rational ligand-design based on a thermodynamic analysis2010
    • Author(s)
      Ui M, Tsumoto K
    • Journal Title

      Recent Pat Biotechnol

      Volume: 4 Pages: 183-188

    • DOI

      10.2174/187220810793611482

    • Data Source
      KAKENHI-PROJECT-21360398

  • [Journal Article] Step-Wise Refolding of Recombinant Proteins.2010
    • Author(s)
      Tsumoto K, Arakawa T, Chen L.
    • Journal Title

      Curr Pharm Biotechnol.

      Volume: 11(3) Pages: 285-288

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Journal Article] Non-Denaturing Solubilization of Inclusion Bodies.2010
    • Author(s)
      津本浩平
    • Journal Title

      Curr Pharm Biotechnol. (掲載確定, 印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Journal Article] Direct and Selective Immobilization of Proteins by Means of an Inorgan is Material-Binding Peptide : Discussion on Functionalization in the Elongation to Material-Binding Peptide.2010
    • Author(s)
      Yokoo N, Thgashi T, Umetsu M, Tsumoto K, Hattori T, Nakanishi T, Ohera S, Takami S, Naka T, Abe H, Kumagai I, Adschiri T.
    • Journal Title

      J.Phys.Chem.B.

      Volume: 114(1) Pages: 480-486

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Journal Article] Salicylate-induced translocation of prestin having mutation in the GTSRH sequence to the plasma membrane.2010
    • Author(s)
      Kumano S, Iida K, Ishihara K, Murakoshi M, Tsumoto K, Ikeda K, Kumagai I, Kobayashi T, Wada H.
    • Journal Title

      FEBS Lett.

      Volume: 584(11) Pages: 2327-2332

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Journal Article] Contribution of the flexible loop region to the function of Staphylococcal enterotoxin B (SEB)2010
    • Author(s)
      Yanaka S, Kudou M, Tanaka Y, Sasaki T, Takemoto S, Sakata A, Hattori Y, Koshi T, Futaki S, Tsumoto K, Nakashima T
    • Journal Title

      Protein Eng.Des.Select.

      Volume: 23(5) Pages: 415-421

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Journal Article] Contribution of the flexible loop region to the function of Staphylococcal enterotoxin B(SEB)2010
    • Author(s)
      Saeko Yanaka, Motonori Kudou, Yoshikazu Tanaka, Takumi Sasaki, Sumiyo Takemoto, Atsuko Sakata Yukio Hattori, Tomoyuki Koshi, Shiro Futaki, Kouhei Tsumoto, and Toshihiro Nakashima
    • Journal Title

      Protein Eng. Des. Select

      Volume: 23 Pages: 415-421

    • DOI

      10.1093/protein/gzq006

    • Data Source
      KAKENHI-PROJECT-21360398

  • [Journal Article] Signal peptide design for improving recombinant protein secretion in the baculovirus expression vector system2010
    • Author(s)
      Futatsumori-Sugai M and Tsumoto K
    • Journal Title

      Biochem. Biophys. Res. Commun

      Volume: 391 Pages: 931-935

    • DOI

      10.1016/j.bbrc.2009.11.167

    • Data Source
      KAKENHI-PROJECT-21360398

  • [Journal Article] The structural mechanism of the inhibition of archaeal Re1E toxin by its cognate Re1B antitoxin.2010
    • Author(s)
      Shinohara M, Guo JX, Mori M, Nakashima T, Takagi H, Nishimoto E, Yamashita S, Tsumoto K, Kakuta Y, Kimura M.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 400(3) Pages: 346-351

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Journal Article] Step-Wise Refolding of Recombinant Proteins.2010
    • Author(s)
      津本浩平
    • Journal Title

      Curr Pharm Biotechnol. (掲載確定, 印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Journal Article] Reactive oxygen species induced by Streptococcus pyogenes invasion trigger apoptotic cell death in infected epithelial cells.2010
    • Author(s)
      Aikawa C, Nozawa T, Maruyama F, Tsumoto K, Hamada S, Nakagawa I.
    • Journal Title

      Cell Microbiol.

      Volume: 12(6) Pages: 814-830

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Journal Article] Expression of antibody variable region-human alkaline pbosphatase fusion proteins in mammalian cells.2010
    • Author(s)
      Sasajima Y, Iwasaki R, Tsumoto K, Kumagai I, Ihara M, Ueda H.
    • Journal Title

      J Immunol Methods.

      Volume: 361(1-2) Pages: 57-63

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Journal Article] Salicylate restores transport function and anion exchanger activity of missense pendrin mutations.2010
    • Author(s)
      Ishihara K, Okuyama S, Kumano S, Iida K, Hamana H, Murakoshi M, Kobayashi T, Usami S, Ikeda K, Haga Y, Tsumoto K Nakamura H, Hirasawa N, Wada H.
    • Journal Title

      Hear Res.

      Volume: 270(1-2) Pages: 110-118

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Journal Article] Signal peptide design for improving recombinant protein secretion in the baculovirus expression vector system2010
    • Author(s)
      Futatsumori-Sugai M, Tsumoto K
    • Journal Title

      Biochem.Biophys.Res.Commun.

      Volume: 391(1) Pages: 931-935

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Journal Article] Solubilization of Membrane Proteins with Novel N-Acylamino Acid Detergents2010
    • Author(s)
      Ryota Abe, Jose M. M. Caaveiro, Motonori Kudou and Kouhei Tsumoto
    • Journal Title

      Mol. Bio Syst

      Volume: 6 Pages: 677-679

    • DOI

      10.1039/b925791h

    • Data Source
      KAKENHI-PROJECT-21360398

  • [Journal Article] Solubilization of Membrane Proteins with Novel N-Acylamino Acid Detergents.2010
    • Author(s)
      Ryota Abe, Jose M.M.Caaveiro, Motonori Kudou, Kouhei Tsumoto
    • Journal Title

      Mol.BioSyst.

      Volume: 6 Pages: 677-679

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Journal Article] Contribution of asparagine residues to the stabilization of a proteinaceous antigen-antibody complex : HyHEL-10-HEL2010
    • Author(s)
      Yokota A., Tsumoto K., Shiroishi M., Nakanishi T., Kondo H., Kumagai I
    • Journal Title

      J.Biol.Chem.

      Volume: 285 Pages: 7686-7696

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Journal Article] Antigen-antibody Binding2010
    • Author(s)
      Kumagai I., 津本浩平
    • Journal Title

      Encyclopedia of Life Sciences (掲載確定, 印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Journal Article] Non-Denaturing Solubilization of Inclusion Bodies.2010
    • Author(s)
      Tsumoto K, Abe R, Ejima D, Arakawa T.Non-Denaturing Solubilization of Inclusion Bodies.
    • Journal Title

      Curr Pharm Biotechnol.

      Volume: 11(3) Pages: 309-310

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Journal Article] Reactive oxygen species induced by Streptococcus pyogenes invasion trigger apoptotic cell death in infected epithelial cells2010
    • Author(s)
      Aikawa C, Nozawa T, Maruyama F, Tsumoto K, Hamada S, Nakagawa I
    • Journal Title

      Cell Microbiol

      Volume: 12 Pages: 814-830

    • DOI

      10.1111/j.1462-5822.2010.01435.x

    • Data Source
      KAKENHI-PROJECT-21360398

  • [Journal Article] 抗原抗体相互作用の熱力学的解析:特異性と親和性2009
    • Author(s)
      津本浩平
    • Journal Title

      熱測定 36

      Pages: 205-215

    • NAID

      10025613091

    • Data Source
      KAKENHI-PROJECT-21360398

  • [Journal Article] To be excluded or to bind, that is the question : Arginine effects on proteins2009
    • Author(s)
      Nakakido M, Kudou M, Arakawa T, and Tsumoto K
    • Journal Title

      Curr. Pharm. Biotechnol

      Volume: 10 Pages: 415-420

    • URL

      http://www.benthamdirect.org/pages/content.php?CPB/2009/00000010/00000004/0010G.SGM

    • Data Source
      KAKENHI-PROJECT-21360398

  • [Journal Article] Contributions of interfacial residues of human Interleukin15 to the specificity and affinity for its private alpha-receptor2009
    • Author(s)
      Sakamoto S, Jose M. M. Caaveiro, Sano E, Tanaka Y, Kudou M and Tsumoto K
    • Journal Title

      J. Mol. Biol

      Volume: 389 Pages: 880-894

    • DOI

      10.1016/j.jmb.2009.04.050

    • Data Source
      KAKENHI-PROJECT-21360398

  • [Journal Article] Immobilized metal affinity chromatography in the presence of arginine2009
    • Author(s)
      Abe R, Kudou M, Tanaka Y, Arakawa T and Tsumoto K
    • Journal Title

      Biochem. Biophys. Res. Commun

      Volume: 381 Pages: 306-310

    • DOI

      10.1016/j.bbrc.2009.01.054

    • Data Source
      KAKENHI-PROJECT-21360398

  • [Journal Article] Utilization of an arginine-elution method for FLAG-tag chromatography2009
    • Author(s)
      Futatsumori-Sugai M, Abe R, Watanabe M, Kudou M, Yamamoto T, Ejima D, Arakawa T, and Tsumoto K
    • Journal Title

      Protein Expr Purif

      Volume: 67 Pages: 148-155

    • DOI

      10.1016/j.pep.2009.03.012

    • Data Source
      KAKENHI-PROJECT-21360398

  • [Journal Article] 相互作用の熱力学情報に基づく低分子リガンド設計2009
    • Author(s)
      津本浩平
    • Journal Title

      薬学雑誌 (掲載確定, 印刷中)

    • NAID

      130000136119

    • Data Source
      KAKENHI-PROJECT-21360398

  • [Journal Article] Grafting of material-binding function into antibodies Functionalization by peptide grafting2008
    • Author(s)
      Hattori T, Umetsu M, Nakanishi T, Tsumoto K, Ohara S, Abe H, Naito M, Asano R, Adschiri T, Kumagai I.
    • Journal Title

      Biochem Biophys Res Commun. 365

      Pages: 751-757

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] アミノ酸を利用したクロマトグラフィー2008
    • Author(s)
      工藤、津本
    • Journal Title

      月刊バイオテクノロジー (掲載確定)

    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] Grafting of material-binding function into antibodies Functionalization by peptide grafting2008
    • Author(s)
      Hattori T., Umetsu M., Nakanishi T., Tsumoto K., Ohara S., Abe H., Naito M.,Asano R., Adschiri T., Kumagai I.
    • Journal Title

      Biochem. Biophys. Res. Commun. 365

      Pages: 751-757

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16106011

  • [Journal Article] Critical contribution of aromatic rings to specific recognition of polyether rings. The case of ciguatoxin CTX3C-ABC and its specific antibody 1C492008
    • Author(s)
      Kouhei Tsumoto
    • Journal Title

      The Journal of Biological Chemistry 283

      Pages: 12259-12266

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16106011

  • [Journal Article] Expression, Purification, Crystallization, and Primary Diffraction Analysis of CapF, a Capsular Polysaccharide Synthesis Enzyme from Staphylococcus aureus2008
    • Author(s)
      Takamitsu Miyafusa, Yoshikazu Tanaka, Makoto Kuroda, Toshiko Ohta, Kouhei Tsumoto
    • Journal Title

      Acta Crystallogr. F (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] Thermodynamic consequences of mutations in Vernier zone residues of a humanized anti-human epidermal growth factor receptor (EGFR) murine antibody, 5282008
    • Author(s)
      Makabe K., Nakanishi T., Tsumoto K., Tanaka Y., Kondo H., Umetsu M., Sone Y., Asano R., Kumagai I.
    • Journal Title

      J. Biol. Chem. 283

      Pages: 1156-1166

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16106011

  • [Journal Article] Critical contribution of aromatic rings to specific recognition of polyether rings:The case of ciguatoxin CTX3C-ABC and its specific antibody IC492008
    • Author(s)
      Tsumoto, et. al.
    • Journal Title

      J Biol Chem (掲載確定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] アミノ酸を利用したクロマトグラフィー2008
    • Author(s)
      工藤、津本
    • Journal Title

      月刊バイオテクノロジー (印刷中)

    • Data Source
      KAKENHI-PROJECT-19021011

  • [Journal Article] Critical contribution of VH-VL interaction to reshaping of an antibody : the case of humanization of anti-lysozyme antibody, HyHEL-102008
    • Author(s)
      Nakanishi T, Tsumoto K, Yokota A, Kondo H, Kumagai I.
    • Journal Title

      Protein Sci. 17(2)

      Pages: 261-270

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] Critical contribution of aromatic rings to specific recognition of polyether rings : The case of ciguatoxin CTX3C-ABC and its specific antibody 1C492008
    • Author(s)
      Tsumoto K^*, Yokota A, Tanaka Y, Ui M, Tsumuraya T, Fujii I, Kumagai I, Nagumo Y, Oguri H, Inoue M, Hirama M.
    • Journal Title

      J Biol Chem. (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] Effect of an amyloidogenic sequence attached to yellow fluorescent protein2008
    • Author(s)
      Hamada D, Tsumoto K, Sawara M, Tanaka N, Nakahira K, Shiraki K, Yanagihara I.
    • Journal Title

      Proteins Struct. Funct. Bioinfor (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] Critical Contribution of VH-VL Interaction to Reshaping of an Antibody : The case of humanization of anti-lysozyme antibody, HyHEL-102008
    • Author(s)
      Nakanishi T., Tsumoto K., Yokota A., Kondo H., Kumagai I.
    • Journal Title

      Protein Sci. 17

      Pages: 261-270

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16106011

  • [Journal Article] A helical string of alternately connected three-helix bundles for the cell wall-associated adhesion protein Ebb from Staphylococcus aureus2008
    • Author(s)
      Tanaka Y, Sakamoto S, Kuroda M, Goda S, Gao YG, Tsumoto K, Hiragi Y, Yao M, Watanabe N, Ohta T, Tanaka I.
    • Journal Title

      Structure 16(3)

      Pages: 488-496

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] Critical contribution of aromatic rings to specific recognition of polyether rings. The case of ciguatoxin CTX3C-ABC and its specific antibody 1C492008
    • Author(s)
      Tsumoto K., Yokota A., Tanaka Y., Ui M., Tsumuraya T., Fujii I., Kumagai I., Nagumo Y., Oguri H., Inoue M., Hirama M.
    • Journal Title

      J. Biol. Chem. 283

      Pages: 12259-12266

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16106011

  • [Journal Article] Critical contribution of aromatic rings to specific recognition of polyether rings2008
    • Author(s)
      Tsumoto K, et.al.
    • Journal Title

      J Biol Chem 283

      Pages: 12259-12266

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19021011

  • [Journal Article] Thermodynamic consequences of mutations in vernier zone residues of a humanized anti-human epidermal growth factor receptor murine antibody, 5282008
    • Author(s)
      Makabe K, Nakanishi T, Tsumoto K, Tanaka Y, Kondo H, Umetsu M, Sane Y, Asano R, Kumagai I.
    • Journal Title

      J Biol Chem. 283(2)

      Pages: 1156-1166

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] Critical contribution of aromatic rings to specific recognition of polyether rings: The case of cituatoxin CTX3C-ABC and its specific antibody 1C49.2008
    • Author(s)
      Tsumoto, et. al.
    • Journal Title

      J. Biol Chem. (印刷中)(掲載決定)

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] Thermodynamic analysis reveals that GTP binding affects the interaction between the alpha- and gamma-subunits of translatio initiation factor 22008
    • Author(s)
      Nakakido M, Tanaka Y, Sokabe M, Tsumoto K.
    • Journal Title

      Biochem Biophys Res Commun (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] How Protein Recognizes Ladder-like Polycycfic Ethers : Interactions between Ciguatoxin (CTX3C) Fragments and Its specific antibody 10C92008
    • Author(s)
      Mihoko Ui, Yoshikazu Tanaka, Takeshi Tsumuraya, Ikuo Fujii, Masayuki Inoue, Masahiro Hirama, Kouhei Tsumoto
    • Journal Title

      J. Biol. Chem. (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] Critical contribution of aromatic rings to specific recognition of polyether rings: The case of ciguatoxin CTX3C-ABC and its specific antibody 1C49.2008
    • Author(s)
      Tsumoto, et. al.
    • Journal Title

      J Biol Chem. (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19021011

  • [Journal Article] Molecular properties. of two proteins homologous to PduO-type ATP : cob(I)alamin adenosyltransferase from Sulfolobus tokodaii2007
    • Author(s)
      Tanaka Y, Sasaki T, Kumagai 1, Yasutake Y, Yao M, Tanaka I, Tsumoto K
    • Journal Title

      Proteins Struct. Funct. Bioinfor. 68

      Pages: 446-457

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] Suppression of protein interactions by arginine : A proposed mechanism of arginine effects2007
    • Author(s)
      Arakawa T, Ejima D, Tsumoto K, Obeyama N, Tanaka Y, Kita Y, Timasheff S. N.
    • Journal Title

      Biophys Chem. 127

      Pages: 1-8

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] Circular dichroism spectra demonstrate formation of the thrombin-binding DNA aptamer G-quadruplex under stabilizing-cation-deficient conditions2007
    • Author(s)
      Nagatoishi S, Tanaka Y, Tsumoto K.
    • Journal Title

      Biochem. Biophys. Res. Comm. 352

      Pages: 812-817

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] Arginine improves protein elution in hydrophobic interaction chromatography. The cases of human interleukin-6 and activin-A.2007
    • Author(s)
      Tsumoto, et. al.
    • Journal Title

      J. Chromatogr. A 1154

      Pages: 81-86

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] Structural consequences of mutaof a protein antigen-antibody complex. The case of HyHEL-10-HEL2007
    • Author(s)
      Shiroishi M., Tsumoto K., Tanaka Y., Yokota A., Nakanishi T., Kondo H., Kumagai I.
    • Journal Title

      J. Biol. Chem. 282

      Pages: 6783-6791

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16106011

  • [Journal Article] A Human antibody fragment with high affinity for biodegradable polymer film2007
    • Author(s)
      Watanabe H., Tsumoto K., Taguchi S., Yamashita K., Doi Y., Nishimiya Y., Kondo H., Umetsu M., Kumagai I.
    • Journal Title

      Bioconjug. Chem. 18

      Pages: 645-651

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16106011

  • [Journal Article] Effects of salts on protein-surface interactions : applications for column chromatography2007
    • Author(s)
      Tsumoto K, Ejima D, Senczuk A. M, Kita Y, Arakawa T
    • Journal Title

      J Pharmaceut. Sci. 96

      Pages: 1677-1690

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] A Human Antibody Fragment with High Affinity for Biodegradable Polymer Film2007
    • Author(s)
      Watanabe H, Tsumoto K, Taguchi S, Yamasbita K, Doi Y, Nishimiya Y, Kondo H, Umetsu M, Kumagai I.
    • Journal Title

      Bioconjugate Chem. 18

      Pages: 645-651

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] Effects of salts on protein-surface interactions:applications for column chromatography2007
    • Author(s)
      Tsumoto, et. al.
    • Journal Title

      J Pharmaceut.Sci 96

      Pages: 1677-1690

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] Arginine improves protein elution in hydrophobic interaction chromatography. The cases of human interleukin-6 and activin-A.2007
    • Author(s)
      Tsumoto, et. al.
    • Journal Title

      J.Chromatogr. A 1154

      Pages: 81-86

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19021011

  • [Journal Article] Arginine improves protein elution in hydrophobic interaction chromatography. The cases of human interleukin-6 and activin-A.2007
    • Author(s)
      Tsumoto K et al.
    • Journal Title

      J. Chromatogr. A (印刷中)

    • Data Source
      KAKENHI-PROJECT-18038007

  • [Journal Article] Effects of salts on protein-surface interactions : applications for column chromatography.2007
    • Author(s)
      Tsumoto K et al.
    • Journal Title

      J.Pharmaceut.Sci. (印刷中)

    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] Improved performance of column chromatography by arginine : Dye-affinity chromatography2007
    • Author(s)
      Arakawa T, Ejima D, Tsumoto K, Isbibashi M, Tokunaga M
    • Journal Title

      Protein Expr. Puri. 52

      Pages: 410-414

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] Effects of salts on protein-surface interactions : applications for column chromatography.2007
    • Author(s)
      Tsumoto K et al.
    • Journal Title

      J. Pharmaceut. Sci. (印刷中)

    • Data Source
      KAKENHI-PROJECT-18038007

  • [Journal Article] Arginine improves protein elution in hydrophobic interaction chromatography. The cases of human interleukin-6 and activin-A.2007
    • Author(s)
      Tsumoto K et al.
    • Journal Title

      J.Chromatogr.A (印刷中)

    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] Effects of acid exposure on the conformation, stability, and aggregation of monoclonal antibodies2007
    • Author(s)
      Ejima D, Tsumoto K, Fukada H, Yumioka R, Nagase K, Arakawa T and Philo J. S.
    • Journal Title

      Proteins Struct. Funct. Bioinfor. 66

      Pages: 954-962

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] Induced binding of proteins by ammonium sulfate in affinity and ion-exchange column chromatography2007
    • Author(s)
      Arakawa T, Tsumoto K, Ejinua D, Kita Y, Yonezawa Y, Tokunaga M
    • Journal Title

      J. Biochem Biophys. Methods 70

      Pages: 493-498

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] Effects of salts on protein-surface interactions: applications for column chromatography.2007
    • Author(s)
      Tsumoto, et. al.
    • Journal Title

      J. Pharmaceut. Sci. 96

      Pages: 1677-1690

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] Structural consequences of mutations in interfacial Tyr residues of a protein antigen-antibody complex : The case of HyHEL-10-HEL2007
    • Author(s)
      Shiroishi M, Tsumoto K, Tanaka Y, Yokota A, Nakanishi T, Kondo H, Kumagai I.
    • Journal Title

      J. Biol. Chem. 282

      Pages: 6783-6791

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] Crystal structure analysis reveals a novel forkhead-associated (FHA) domain of ESAT-6 secretion system C (EssC) protein in Staphylococcus aureus2007
    • Author(s)
      Tanaka Y, Kuroda M, Yasutake Y, Yao M, Tsumoto K, Watanabe M, Ohta T, Tanaka I
    • Journal Title

      Proteins Struct. Funct. Bioinfor. 69

      Pages: 659-664

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] Effects of salts on protein-surface interactions: applications for column chromatography.2007
    • Author(s)
      Tsumoto, et. al.
    • Journal Title

      J Pharmaceut. Sci. 96

      Pages: 1677-1690

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19021011

  • [Journal Article] Structural and Mutational analyses of Drp35 from Staphylococcus aureus : a possible mechanism for its lactonase activity2007
    • Author(s)
      Tanaka Y, Morikawa K, Ohki Y, Yao. M, Tsumoto K, Watanabe N, Ohta T, Tanaka I
    • Journal Title

      J. Biol. Chem. 282

      Pages: 5770-5780

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] The effects of arginine on protein binding and elution in hydrophobic interaction and ion-exchange chromatography2007
    • Author(s)
      Arakawa T, Tsumoto K, Nagase K, Ejima D
    • Journal Title

      Protein Expr. Purif. 54

      Pages: 110-116

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] The N-terminal domain of elastin-binding protein of Staphylococcus aureus changes its secondary structure in a membrane-mimetic environment2007
    • Author(s)
      Nakakido M, Tanaka Y, Tsumoto K.
    • Journal Title

      J. Biochem. 142

      Pages: 131-134

    • NAID

      10020096902

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] Arginine improves protein elution in hydrophobic interaction chromatography. The cases of human interleukin-6 and activin-A2007
    • Author(s)
      Tsumoto K, Ejima D, Nagase K, Arakawa T.
    • Journal Title

      J. Chromatogr. A 1154

      Pages: 81-86

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] Arginine improves protein elution in hydrophobic interaction chromatography.The cases of human interleukin-6 and activin-A2007
    • Author(s)
      Tsumoto, et. al.
    • Journal Title

      J.Chromatogr.A 1154

      Pages: 81-86

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] クロマトグラフィ-における凝集抑制と溶媒制御2006
    • Author(s)
      津本, ら
    • Journal Title

      生物工学会誌

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] Humanization of the bispecific EGFR×CD3 diabody and its efficacy as a potential clinical reagent2006
    • Author(s)
      Ryutaro Asano, Yukiko Sone, Koki Makabe, Kouhei Tsumoto, Hiroki Hayashi, Yu Katayose, Michiaki Unno, Toshio Kudo, Izumi Kumagai
    • Journal Title

      Clinical Cancer Research 12

      Pages: 4036-4042

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] プロテインマニピュレーション : 蛋白質リフォールディングの最先端2006
    • Author(s)
      津本 浩平ら
    • Journal Title

      化学と生物

    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] Efficient leukocyte IG-like receptor signaling and crystal structure of disulfide-linked HLA-G dimer2006
    • Author(s)
      Shiroishi M, Kuroki K, Ose T, Rasubala L, Shiratori I, Arase H, Tsumoto K, Kumagai I, Kohda D, Maenaka K.
    • Journal Title

      J. Biol. Chem. 281

      Pages: 10439-10447

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] Entropically driven MHC class I recognition by human inhibitory receptor leukocyte Ig-like receptor B1 (LILRB1/ILT2/CD85j)2006
    • Author(s)
      Shiroishi M., Kuroki K., Tsumoto K., Yokota A., Sasaki T., Amano K., Shimojima T., Shirakihara Y., Rasubala L., van der MerKohda D., Maenaka K.
    • Journal Title

      J. Mol. Biol. 355

      Pages: 237-248

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16106011

  • [Journal Article] 蛋白質折りたたみの人工制御:プロテインマニピュレ-ション2006
    • Author(s)
      津本, ら
    • Journal Title

      未来材料

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] Entropically driven MHC class I recognition by human inhibitory receptor leukocyte Ig-like receptor B1 (LILRBI/ILT2/CD85j)2006
    • Author(s)
      Shiroishi M, Kuroki K, Tsumoto K, Yokota A, Sasaki T, Amano K, Shimojima T, Shirakihara Y, Rasubala L, van der Merwe PA, Kumagai I, Kohda D, Maenaka K.
    • Journal Title

      J. Mol. Biol. 355

      Pages: 237-248

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] 抗原抗体相互作用における特異性・親和性創出機構の精密解析2006
    • Author(s)
      津本 浩平
    • Journal Title

      生化学 (印刷中)

    • NAID

      10017291659

    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] Efficient leIg-like receptor signaling and crystal structure of disulfide-linked HLA-G dimer2006
    • Author(s)
      Shiroishi M., Kuroki K., Ose T., Rasubala L., Shiratori I., Arase H., Tsumoto K., Kumagai I., Kohda D., Maenaka K.
    • Journal Title

      J. Biol. Chem. 281

      Pages: 10439-10447

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16106011

  • [Journal Article] 蛋白質折りたたみの人工制御 : プロテインマニピュレーション2006
    • Author(s)
      津本 浩平ら
    • Journal Title

      未来材料

    • Data Source
      KAKENHI-PROJECT-18038007

  • [Journal Article] Humanization of the bispecific epidermal growth or receptor x CD3 diabody and its efficacy as a potential clinical reagent,2006
    • Author(s)
      Asano R., Sone Y., Makabe K., Tsumoto K., Hayashi H., Katayose Y., Unno M., Kudo T., Kumagai I.
    • Journal Title

      Clin. Cancer Res. 12

      Pages: 4036-4042

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16106011

  • [Journal Article] A novel "reverse screening" to identify refolding additives for activin-A2006
    • Author(s)
      Daisuke Ejima, Kunio Ono, Kouhei Tsumoto*, Tsutomu Arakawa, Yuzuru Eto
    • Journal Title

      Protein Expression and Purification 47

      Pages: 45-51

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] 蛋白質折りたたみの人工制御 : プロテインマニピュレーション2006
    • Author(s)
      津本 浩平ら
    • Journal Title

      未来材料

    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] 蛋白質リフォ-ルディングの最先端:プロテインマニピュレ-ション2006
    • Author(s)
      津本, ら
    • Journal Title

      化学と生物

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] Structural basis for recognition of the nonclassical MHC molecule HLA-G by the leukocyte Ig-like receptor B2 (LILRB2ILIR2/ILT4/CD85d)2006
    • Author(s)
      Shiroishi M, Kuroki K, Rasubala L, Tsumoto K, Kumagai I, Kurimoto E, Kato K, Kohda D, Maenaka K.
    • Journal Title

      Proc Natl Acad Sci USA. 103

      Pages: 16412-16417

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] Structural basis for reon of the nonclassical MHC molecule HLA-G by the leukocyte Ig-like receptor B2 (LILRB2/LIR2/ILT4/CD85d)2006
    • Author(s)
      Shiroishi M., Kuroki K., Rasubala L., Tsumoto K., Kumagai I., Kurimoto E., Kato K., Kohda D., Maenaka K.
    • Journal Title

      Proc. Natl. Acad. Sci. USA 103

      Pages: 16412-16417

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16106011

  • [Journal Article] クロマトグラフィーにおける凝集抑制と溶媒制御2006
    • Author(s)
      津本 浩平ら
    • Journal Title

      生物工学会誌

    • Data Source
      KAKENHI-PROJECT-18038007

  • [Journal Article] Review : Small molecule pharmacological chaperones : from thermodynamic stabilization to pharmaceutical drugs2006
    • Author(s)
      Tsutomu Arakawa, Daisuke Ejima, Yoshiko Kita, Kouhei Tsumoto
    • Journal Title

      Biochim. Biophis. Acta 1764

      Pages: 1677-1687

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] 抗原抗体相互作用における特異性・親和性創出機構の精密解析2006
    • Author(s)
      津本
    • Journal Title

      生化学 78

      Pages: 93-109

    • NAID

      10017291659

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] プロテインマニピュレーション : 蛋白質リフォールディングの最先端2006
    • Author(s)
      津本 浩平ら
    • Journal Title

      化学と生物

    • Data Source
      KAKENHI-PROJECT-18038007

  • [Journal Article] Aggregation suppression of proteins by arginine during thermal unfolding2006
    • Author(s)
      Arakawa T, Kita Y, Ejima D, Tsumoto K, Fukada H.
    • Journal Title

      Protein Pept Lett. 13

      Pages: 921-927

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] クロマトグラフィーにおける凝集抑制と溶媒制御2006
    • Author(s)
      津本 浩平ら
    • Journal Title

      生物工学会誌

    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] Daisuke EjimaBiotech Applications of Arginine : Novel Uses in Protein Production, Processing, Analysis, and Formulation2005
    • Author(s)
      Tsutomu Arakawa, Kouhei Tsumoto
    • Journal Title

      BioProcess International 3

      Pages: 20-28

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] Tumor-directed lymphocyte-activating cytokines : refolding-based preparation of recombinant human interleukin-12 and an antibody variable domain-fused protein by additive-intoduced stepwise dialysis2005
    • Author(s)
      Makabe K., Asano R., Ito T., Tsumoto K., Kudo T., Kumagai I.
    • Journal Title

      Biochem. Biophys. Res. Commun. 328

      Pages: 98-105

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16106011

  • [Journal Article] Arginine reduces non-specific protein binding in gel filtration2005
    • Author(s)
      Daisuke Ejima, Ryosuke Yumioka, Tsutomu Arakawa, Kouhei Tsumoto
    • Journal Title

      Journal of Chromatography A 1094

      Pages: 49-55

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] Review: Why is Arginine Effective in Suppressing Aggregation?2005
    • Author(s)
      Tsumoto, et. al.
    • Journal Title

      Pep. Protein Lett. 12

      Pages: 613-619

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] Review : Why is Arginine Effective in Suppressing Aggregation2005
    • Author(s)
      Kohei Tsumoto, Daisuke Ejima, Yoshiko Kita, Tsutomu Arakawa
    • Journal Title

      Pep. Protein Lett. 12

      Pages: 613-619

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] Bioassistance for preferential immobilization of ZnO and synthesis of nanostrucrized ZnO forming a flower-type morphology2005
    • Author(s)
      Mitsuo Umetsu, Masamichi Mizuta, Satoshi Ohara, Seiichi Takami, Hideki Watanabe, Kouhei Tsumoto, Izumi Kumagai, Tadafumi Adschiri
    • Journal Title

      Advanced Materials 17

      Pages: 2571-2575

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] Characterization of Arginine as a Solvent Additive : A Halophilic Enzyme as a Model Protein2005
    • Author(s)
      Matsujiro Ishibashi, Kohei Tsumoto, Daisuke Ejima, Tsutomu Arakawa, Masao Tokunaga
    • Journal Title

      Pep. Protein Lett. 12

      Pages: 649-653

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] Nondenaturing solubilization of beta2 microglobulin from inclusion bodies by L-arginine2005
    • Author(s)
      Umetsu M., Tsumoto K., Nitta S., Adschiri T., Ejima D., Arakawa T., Kumagai I.
    • Journal Title

      Biochem. Biophys. Res. Commun. 328

      Pages: 189-197

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16106011

  • [Journal Article] Bioassisted room-temperature immobilization and mineralization of zinc oxide -The structural ordering of ZnO nanoparticles into a flower-type morphorogy2005
    • Author(s)
      Umetsu M., Mizuta M., Tsumoto K., Ohara S., Takami S., Watanabe H., Kumagai I., Adschiri T.
    • Journal Title

      Adv. Mater. 17

      Pages: 2571-2575

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16106011

  • [Journal Article] Review : Why is Arginine Effective in Suppressing Aggregation?2005
    • Author(s)
      Kohei Tsumoto et al.
    • Journal Title

      Pep.Protein Lett. 12

      Pages: 613-619

    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] Effective elution of antibodies by arginine and arginine derivatives in affinity column chromatography2005
    • Author(s)
      Daisuke Ejima, Ryosuke Yumioka, Kouhei Tsumoto, Tsutomu Arakawa
    • Journal Title

      Analytical Biochemistry 345

      Pages: 250-257

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] Crystal structure of the hypothetical protein ST2072 from Sulfolobus tokodaii2005
    • Author(s)
      Yoshikazu Tanaka, Kouhei Tsumoto, Eiki Tanabe, Yoshiaki Yasutake, Naoki Sakai, Min Yao, Isao Tanaka, Izumi Kumagai
    • Journal Title

      Proteins Structure Function and Bioinformatics 61

      Pages: 1127-1131

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] Mini Review : Is arginine a protein-denaturant2005
    • Author(s)
      Matsujiro Ishibashi, Kouhei Tsumoto, Masao Tokunaga, Daisuke Ejima, Yoshiko Kita and Tsutomu Arakawa
    • Journal Title

      Protein Exp. Purif. 42

      Pages: 1-6

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Journal Article] Why is Arginine Effective in Suppressing Aggregation?2005
    • Author(s)
      Kohei Tsumoto, et al.
    • Journal Title

      Pep.Protein Lett. 12

      Pages: 613-619

    • Data Source
      KAKENHI-PROJECT-16106011

  • [Journal Article] Glorioso J.C., Herpes simplex virus targeting to the EGF receptor by a gD-specific soluble bridging molecule2005
    • Author(s)
      Nakano K., Asano R., Tsumoto K., Kwon H., Goins W.F., Kumagai I., Cohen J.B.
    • Journal Title

      Mol. Ther. 11

      Pages: 617-626

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16106011

  • [Journal Article] Pathway to insoluble aggregates on the refolding of a single-chain Fv antibody: morphological changes of aggregated protein onrefolding2004
    • Author(s)
      Umetsu M., Ashish K., Tsumoto K., Kumagai I.
    • Journal Title

      Chem. Lett. (Jpn.) 33

      Pages: 1600-1601

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16106011

  • [Journal Article] Phage-display selection of antibodies to the left end of CTX3C using synthetic fragments,2004
    • Author(s)
      Nagumo Y., Oguri H., Tsumoto K., Shindo Y., Hirama M., Tsumuraya T., Fujii I., Tomioka Y., Mizugaki M., Kumagai I.
    • Journal Title

      J. Immunol. Meth. 289

      Pages: 137-146

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16106011

  • [Journal Article] Review : Role of arginine in protein refolding, solubilization, and purification.2004
    • Author(s)
      Kouhei Tsumoto, et al.
    • Journal Title

      Biotechnology Progress 20

      Pages: 301-308

    • Data Source
      KAKENHI-PROJECT-14704006

  • [Journal Article] Review : Role of arginine in protein refolding, solubilization, and purification.2004
    • Author(s)
      Kouhei Tsumoto, et al.
    • Journal Title

      Biotechnology Progress 20

      Pages: 301-308

    • Data Source
      KAKENHI-PROJECT-16041204

  • [Journal Article] A highly effectivbispecific diabody for cancer immunotherapy : cure of xenografted tumors by bispecific diabody and T-LAK cells2004
    • Author(s)
      Hayashi H., Asano R., Tsumoto K., Katayose Y., Suzuki M., Unno M., Kodama H., Takemura S., Yoshida H., Makabe K., Imai K., Matsuno S., Kumagai I., Kudo T.
    • Journal Title

      Cancer Immunol. Immunother. 53

      Pages: 497-509

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16106011

  • [Journal Article] Fucose depletion from human IgG1 oligosaccharide enhancbinding enthalpy and association rate between IgG1 and FcγRIIIa2004
    • Author(s)
      Okazaki A., Shoji-Hosaka E., Nakamura K., Wakitani M., Uchida K., Kakita S., Tsumoto K., Kumagai I., Shitara K.
    • Journal Title

      J. Mol. Biol. 336

      Pages: 1239-1249

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16106011

  • [Journal Article] Review : Role of arginine in protein refolding, solubilization, and purification2004
    • Author(s)
      Kouhei Tsumoto, et al.
    • Journal Title

      Biotechnology Progress 20

      Pages: 301-308

    • Data Source
      KAKENHI-PROJECT-16106011

  • [Patent] 全身性炎症反応症候群の治療又は予防剤2013
    • Inventor(s)
      浜窪隆雄、津本浩平
    • Industrial Property Rights Holder
      国立大学法人東京大学、学校法人順天堂
    • Industrial Property Rights Type
      特許
    • Filing Date
      2013
    • Acquisition Date
      2017
    • Data Source
      KAKENHI-PROJECT-25220205

  • [Patent] 抗体改変による疾患部位特異的な診断薬・治療薬の集積法2009
    • Inventor(s)
      浜窪隆雄、津本浩平, 他
    • Industrial Property Rights Holder
      東大TLO
    • Filing Date
      2009-04-09
    • Overseas
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Patent] 抗体改変による疾患部位特異的な診断薬・治療薬の集積法2009
    • Inventor(s)
      浜窪隆雄、津本浩平, 他
    • Industrial Property Rights Holder
      東大TLO
    • Filing Date
      2009-04-09
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Patent] 新規なダイアボディ型二重特異性抗体2006
    • Inventor(s)
      熊谷泉, 工藤俊雄, 津本浩平, 浅野竜太郎
    • Industrial Property Rights Holder
      東北テクノアーチ
    • Filing Date
      2006-05-19
    • Data Source
      KAKENHI-PROJECT-16106011

  • [Presentation] 物理化学的アプローチによる低分子阻害剤の探索および抗体阻害剤の開発2020
    • Author(s)
      中木戸 誠、相川 知宏、長門石 曉、妹尾 暁暢、竹内 美結、星野 将人、下村 拓矢、カアベイロ ホセ、中川 一 路、津本 浩平
    • Organizer
      第93回日本細菌学会総会
    • Invited
    • Data Source
      KAKENHI-PLANNED-19H05766

  • [Presentation] Molecular Basis for Heme Extraction of the Antimicrobial Target IsdH from Staphylococcus aureus from Human Hemoglobin2020
    • Author(s)
      S. Valenciano, V. T. Nhuan, M. Nakakido, J. M.M. Caaveiro, K. Tsumoto
    • Organizer
      Biophysical Society 2020
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05766

  • [Presentation] Thermodynamic, kinetic and computational analyses of the recognition mechanism of an antibody to a flexible protein antigen2019
    • Author(s)
      金田生穂、長門石 曉、黒田 大祐、中木戸 誠、カアベイロ ホセ、津本　浩平
    • Organizer
      CBI学会2019年大会
    • Data Source
      KAKENHI-PLANNED-19H05766

  • [Presentation] Recent analytical approach for evaluating protein formulation in biopharmaceuticals2019
    • Author(s)
      Kouhei Tsumoto
    • Organizer
      PITTCON2019
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] 蛋白質相互作用の熱測定と創薬2019
    • Author(s)
      長門石曉、津本浩平
    • Organizer
      第57回生物物理学会年会
    • Invited
    • Data Source
      KAKENHI-PLANNED-19H05766

  • [Presentation] 次世代抗体医薬への工学的アプローチ2019
    • Author(s)
      津本浩平
    • Organizer
      第32回バイオメディカル分析科学シンポジウム
    • Invited
    • Data Source
      KAKENHI-PLANNED-19H05766

  • [Presentation] ホモ二量体形成蛋白質P-カドヘリンによる細胞接着阻害を可能にする新規低分子リガンド結合部位の同定2019
    • Author(s)
      妹尾暁暢、長門石 曉、吉田 浩平、伊藤 翔、上野 剛、田島 卓実、工藤 翔太、津本 浩平
    • Organizer
      第92回日本生化学会大会
    • Data Source
      KAKENHI-PLANNED-19H05766

  • [Presentation] 足場蛋白質Adhironに移植したαへリックスの構造解析2019
    • Author(s)
      住川太一、中木戸 誠、黒田 大祐、津本 浩平
    • Organizer
      第19回　日本蛋白質科学会年会
    • Data Source
      KAKENHI-PLANNED-19H05766

  • [Presentation] DESIGN AND BIOPHYSICAL EVALUATION OF Β-HAIRPIN PEPTIDES DERIVED FROM SINGLE-DOMAIN VHH ANTIBODIES2019
    • Author(s)
      山本晃一、中木戸 誠、黒田 大祐、長門石 曉、森本 淳平、山東 信介、津本 浩平
    • Organizer
      第56回ペプチド討論会
    • Data Source
      KAKENHI-PLANNED-19H05766

  • [Presentation] S100A4-MetAP2間相互作用に対するHelix-turn-helix構造を形成するペプチド 阻害剤の解析2019
    • Author(s)
      片桐直宏、長門石 曉、遠藤 英也、津本 浩平
    • Organizer
      第37回メディシナルケミストリーシンポジウム
    • Data Source
      KAKENHI-PLANNED-19H05766

  • [Presentation] Molecular dissection of antigen recognition by methylated lysine specific antibodies2019
    • Author(s)
      Nakakido M, Ishii M, Kuroda D,Jose M.M. Caaveiro, Okumura S, Maruyama T, Kevin Entzminger,Tsumoto K
    • Organizer
      第19回　日本蛋白質科学会年会
    • Data Source
      KAKENHI-PLANNED-19H05766

  • [Presentation] がん転移に関するLI-cadherin一塩基多型の分子メカニズム2019
    • Author(s)
      由井杏奈、菊池 智佳、郷田 秀一郎、工藤 翔太、秋葉 宏樹、中木戸 誠、黒田大祐、長門石 曉、新井 修、岩成 宏子、浜窪 隆雄、津本 浩平
    • Organizer
      第92回日本生化学会大会
    • Data Source
      KAKENHI-PLANNED-19H05766

  • [Presentation] 物理化学測定と分子シミュレーションを用いた抗体親和性成熟過程の解析2019
    • Author(s)
      樋渡隼人、黒田 大祐、中木戸 誠、津本 浩平
    • Organizer
      第19回　日本蛋白質科学会年会
    • Data Source
      KAKENHI-PLANNED-19H05766

  • [Presentation] 次世代抗体工学と臨床プロテオゲノミクス研究2019
    • Author(s)
      津本浩平
    • Organizer
      臨床プロテオジェノミクス学会
    • Invited
    • Data Source
      KAKENHI-PLANNED-19H05766

  • [Presentation] 化膿レンサ球菌の鉄獲得蛋白質MtsAの特性評価及び抗体阻害剤の探索2019
    • Author(s)
      竹内美結、中木戸 誠、津本 浩平
    • Organizer
      第19回　日本蛋白質科学会年会
    • Data Source
      KAKENHI-PLANNED-19H05766

  • [Presentation] ヒト化VHH人工合成ライブラリー構築を目指した合成ヒト化VHHの物性機能解析2019
    • Author(s)
      木下清晶、森 千夏、中木戸 誠、黒田 大祐、津本 浩平
    • Organizer
      第19回　日本蛋白質科学会年会
    • Data Source
      KAKENHI-PLANNED-19H05766

  • [Presentation] PRDM14の特異的制御を指向したPRDM14-EED間相互作用の物理化学解析2019
    • Author(s)
      大西亮輔、長門石 曉、谷口 博昭、津本 浩平
    • Organizer
      第42回日本分子生物学会年会
    • Data Source
      KAKENHI-PLANNED-19H05766

  • [Presentation] Development and analysis of bispecific antibody for hROBO12019
    • Author(s)
      Yuji Watanabe, Makoto Nakakido, Satoru Nagatoishi, Takao Hamakubo, Kouhei Tsumoto
    • Organizer
      Antibody Engineering & Therapeutics
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] 分子動力学シミュレーションを用いたCDR-Graftingによる合成単ドメイン抗体の構造的変化の解析2019
    • Author(s)
      木下清晶、森千夏、中木戸誠、黒田大祐、カアベイロホセ、津本浩平
    • Organizer
      第57回　日本生物物理学会年会
    • Data Source
      KAKENHI-PLANNED-19H05766

  • [Presentation] The efffects of protonation pf a phosphorylated amino acid on the molecular recongnation:Comparative studies of generic proteins and an antibody2019
    • Author(s)
      R. Kawade, D. Kuroda, J. M. M. Caaveiro, CJ Okumura, T. Maruyama, K. Entzminger, K. Tsumoto
    • Organizer
      33rd The Protein Society Annual Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05766

  • [Presentation] VHH抗体CDR3を利用したβ-hairpin型ペプチド設計法の検討2019
    • Author(s)
      山本晃一、中木戸 誠、黒田 大祐、長門石 曉、森本 淳平、山東 信介、津本 浩平
    • Organizer
      第42回日本分子生物学会年会
    • Data Source
      KAKENHI-PLANNED-19H05766

  • [Presentation] Structural insight into inhibition of homophilic dimerization mediated by cell adhesion protein P-cadherin utilizing a small molecule ligand2019
    • Author(s)
      妹尾暁暢、長門石 曉、吉田 浩平、伊藤 翔、上野 剛、田島 卓実、工藤 翔太、津本 浩平
    • Organizer
      第19回日本蛋白質科学会年会／第71回日本細胞生物学会大会合同年次大会
    • Data Source
      KAKENHI-PLANNED-19H05766

  • [Presentation] コンピューター技術を用いた抗体立体構造予測と分子設計2019
    • Author(s)
      黒田大祐、津本浩平
    • Organizer
      第19回日本蛋白質科学会年会／第71回日本細胞生物学会大会合同年次大会
    • Invited
    • Data Source
      KAKENHI-PLANNED-19H05766

  • [Presentation] 次世代抗体医薬品開発：加速する現状2019
    • Author(s)
      津本浩平
    • Organizer
      ラマンフェスタ
    • Invited
    • Data Source
      KAKENHI-PLANNED-19H05766

  • [Presentation] 病原性微生物における鉄獲得関連蛋白質の特性評価および抗体阻害剤の探索2019
    • Author(s)
      中木戸誠、竹内美結、津本浩平
    • Organizer
      第19回日本蛋白質科学会年会／第71回日本細胞生物学会大会合同年次大会
    • Invited
    • Data Source
      KAKENHI-PLANNED-19H05766

  • [Presentation] Characterization of ligand-specificity of red pigment concentrating hormone receptpr of the kuruma prawn Marsupenaeus japonicus2019
    • Author(s)
      田部亜季、中木戸 誠、山本 菜央佳、中野 和民、内丸 薫、津本 浩平
    • Organizer
      第19回　日本蛋白質科学会年会
    • Data Source
      KAKENHI-PLANNED-19H05766

  • [Presentation] 腫瘍細胞に高発現するPRDM14の機能解析と制御剤探索2019
    • Author(s)
      大西亮輔、長門石 曉、谷口 博昭、津本 浩平
    • Organizer
      第37回メディシナルケミストリーシンポジウム
    • Data Source
      KAKENHI-PLANNED-19H05766

  • [Presentation] Disruption of Homophilic Protein-protein Interaction of P-cadherin by A Fragment Compound as A Trigger To Inhibit Cell Adhesion2019
    • Author(s)
      A. Senoo, S.Nagatoishi, K. Yoshida, S. Ito, G. Ueno, T. Tashima, S. Kudo, K. Tsumoto
    • Organizer
      33rd The Protein Society Annual Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05766

  • [Presentation] 物理化学的手法を駆使した細胞接着蛋白質P-カドヘリンのホモ二量体化相互作用を阻害する低分子の同定とその阻害機構解明2019
    • Author(s)
      妹尾暁暢、齋藤 雄太朗、伊藤 翔、長門石 曉、上野 剛、吉田 浩平、田島 卓実、工藤 翔太、山東 信介、津本 浩平
    • Organizer
      第37回メディシナルケミストリーシンポジウム
    • Data Source
      KAKENHI-PLANNED-19H05766

  • [Presentation] Biophysics of the Protein-ligand Interactions to Regulate the Protein Function2019
    • Author(s)
      S. Nagatoishi, K. Tsumoto
    • Organizer
      10th RSC-CSJ Joint Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05766

  • [Presentation] S100A4-MetAP2蛋白質間相互作用に対するペプチド阻害剤の相互作用解析2019
    • Author(s)
      片桐直宏、長門石 曉、遠藤 英也、津本 浩平
    • Organizer
      第19回　日本蛋白質科学会年会
    • Data Source
      KAKENHI-PLANNED-19H05766

  • [Presentation] 新規抗がん治療を指向したPRELP-TGFβ1相互作用の物理化学的解析2019
    • Author(s)
      小菅啓史、中木戸誠、長門石曉、大沼信一、津本浩平
    • Organizer
      第92回日本生化学会大会
    • Data Source
      KAKENHI-PLANNED-19H05766

  • [Presentation] 分析科学が先導する次世代バイオ医薬品研究開発2019
    • Author(s)
      津本浩平
    • Organizer
      JASIS2019
    • Invited
    • Data Source
      KAKENHI-PLANNED-19H05766

  • [Presentation] 腫瘍細胞に高発現するPRDM14の物理化学解析と制御剤探索2019
    • Author(s)
      大西亮輔、長門石 曉、谷口 博昭、津本 浩平
    • Organizer
      第10回スクリーニング学研究会
    • Data Source
      KAKENHI-PLANNED-19H05766

  • [Presentation] 次世代抗体医薬品開発：現状と今後2019
    • Author(s)
      津本浩平
    • Organizer
      第12回複合糖質・糖鎖部会
    • Invited
    • Data Source
      KAKENHI-PLANNED-19H05766

  • [Presentation] 熱力学・速度論に基づく抗Shh抗体の抗原結合様式解析2019
    • Author(s)
      金田生穂、長門石 曉、中木戸 誠、黒田 大祐、津本 浩平
    • Organizer
      第19回　日本蛋白質科学会年会
    • Data Source
      KAKENHI-PLANNED-19H05766

  • [Presentation] 小分子リガンドによる細胞接着蛋白質P-カドヘリンの分子間相互作用制御と構造情報に基づくリガンド設計2019
    • Author(s)
      妹尾暁暢、齋藤 雄太朗、伊藤 翔、長門石 曉、上野 剛、吉田 浩平、田島 卓実、工藤 翔太、山東 信介、津本 浩平
    • Organizer
      第13回バイオ関連化学シンポジウム
    • Data Source
      KAKENHI-PLANNED-19H05766

  • [Presentation] 転写調節因子PRDM14の天然変性領域とEED間における物理化学的相互作用解析2019
    • Author(s)
      大西亮輔、長門石 曉、谷口 博昭、津本 浩平
    • Organizer
      第19回　日本蛋白質科学会年会
    • Data Source
      KAKENHI-PLANNED-19H05766

  • [Presentation] How We Can Improve the Affinity of An Antibody2019
    • Author(s)
      津本浩平
    • Organizer
      国際生物無機化学会議
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-19H05766

  • [Presentation] Local hydrophobic exposure of proteins regulated by hydration changes and its adsorption on a COP plastic surface2019
    • Author(s)
      長門石曉、津本浩平
    • Organizer
      第19回日本蛋白質科学会年会／第71回日本細胞生物学会大会合同年次大会
    • Invited
    • Data Source
      KAKENHI-PLANNED-19H05766

  • [Presentation] 菌種特異性な増殖阻害剤の開発2018
    • Author(s)
      中木戸誠、相川知宏、中川一路、津本浩平
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-17K19552

  • [Presentation] 分子シミュレーションと物理化学的解析による安定化抗体の設計2018
    • Author(s)
      河上 恵理、黒田 大祐、中木戸 誠、津本 浩平
    • Organizer
      第18回日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] A群レンサ球菌の増殖を抑制する新規薬剤の探索と評価2018
    • Author(s)
      相川知宏、星野将人、中木戸誠、長門石暁、津本浩平、中川一路
    • Organizer
      第71回日本細菌学会関西支部総会
    • Data Source
      KAKENHI-PROJECT-17K19552

  • [Presentation] 合理的な抗体設計を目指した蛋白質相互作用に関する物理化学解析2018
    • Author(s)
      長門石曉、津本浩平
    • Organizer
      バイオ医薬品セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] ドラッグデリバリーの標的特異性創出を目的と した部位特異的化学修飾可能な抗 OX40単鎖 抗体の取得と機能解析2018
    • Author(s)
      田部 亜季、中野 和民、中木戸 誠、長門石 曉、田中 勇悦、津本 浩平、内丸 薫、渡邉 俊樹
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] Nanodisc-GPCRを用いた物理化学的アプローチによる低分子薬剤探索2018
    • Author(s)
      吉田 浩平、長門石 曉、黒田 大祐、津本 浩平
    • Organizer
      第9回スクリーニング学研究会
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] 病原性微生物における鉄獲得関連蛋白質の物理化学解析と新規抗菌剤の探索2018
    • Author(s)
      中木戸 誠、妹尾 暁暢、サンドラ バレンシアノ、星野 将人、相川 知宏、長門石 曉、ホセ カアベイロ、中川 一路、津本 浩平
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] 化膿連鎖球菌の鉄獲得機構を阻害する新規低分子・抗体の取得2018
    • Author(s)
      妹尾 暁暢、星野 将人、中木戸 誠、長門石 曉、相川 知宏、中川 一路、津本 浩平
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] SPRを用いた化膿連鎖球菌の宿主感染関連PPIを阻害する天然物化合物の探索2018
    • Author(s)
      妹尾 暁暢、長門石 曉、中木戸 誠、星野 将人、中山 登、坂東 泰彦、石崎 仁將、澤 竜一、五十嵐 雅之、津本 浩平
    • Organizer
      第9回スクリーニング学研究会
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] Raman Spectroscopy for Biopharmaceutics: Evaluation of Conformational Stability2018
    • Author(s)
      Satoru Nagatoishi, Kouhei Tsumoto
    • Organizer
      RamanFest 2018 (6th International Conference on Advanced Applied Raman Spectroscopy)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] 蛋白質相互作用解析と次世代創薬への期待2018
    • Author(s)
      津本浩平
    • Organizer
      生物工学会バイオ計測研究会　第1回シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] リステリア菌感染におけるE-cadherin-InlA間相互作用を阻害する低分子及びVHHの探索2018
    • Author(s)
      山﨑 太一、長門石 曉、中木戸 誠、ホセ カアベイロ、三室 仁美、津本 浩平
    • Organizer
      第18回日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] Physicochemical and Computational Analysis for S100A4-MetAP2 peptide Interaction2018
    • Author(s)
      Naohiro Katagiri, Satoru Nagatoishi, Hideya Endo, Kouhei Tsumoto
    • Organizer
      Asian Biophysics Association Symposium in conjunction with the Australian Society for Biophysics Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] メチル化リジン特異的抗体のメチル基認識機構の解析2018
    • Author(s)
      石井 美咲、木戸 誠、奥村 繁、丸山 俊昭、Kevin Entzminger、津本浩平
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] 物理化学測定を用いた異なる脂質環境におけるセロトニン受容体の機能評価2018
    • Author(s)
      吉田 浩平、長門石 曉、津本 浩平
    • Organizer
      第18回日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] LI-cadherinのTrp残基への変異導入がホモ二量体形成に与える影響2018
    • Author(s)
      由井 杏奈、菊池 智佳、郷田 秀一郎、工藤 翔太、秋葉 宏樹、中木戸 誠、長門石 曉、新井 修、岩成 宏子、浜窪 隆雄、津本 浩平
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] 蛋白質相互作用の物理化学的解析と次世代創薬2018
    • Author(s)
      津本浩平、長門石曉
    • Organizer
      第56回生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] Role of linker region in heme transporter IsdH from Staphylococcus aureus2018
    • Author(s)
      バレンシアノ サンドラ、シュスコ タチアナ、中木戸 誠、カアベイロ ホセ、津本浩平
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] 天然変性タンパク質のフラグメント化によるタンパク質間相互作用阻害リガンド探索2018
    • Author(s)
      長門石曉、津本浩平
    • Organizer
      第12回バイオ関連化学シンポジウム
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] 細胞内の蛋白質間相互作用を制御する物理化学的リガンド探索2018
    • Author(s)
      長門石曉、津本浩平
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] SPRを活用した鉄獲得機構を標的とした化膿連鎖球菌に対する新規抗菌剤の探索2018
    • Author(s)
      妹尾 暁暢、長門石 曉、福田 哲也、小尾 奈緒子、中山 登、坂東 泰彦、石崎 仁將、澤 竜一、五十嵐 雅之、津本 浩平
    • Organizer
      第18回日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] シングルドメイン抗体を用いたインターロイキンのシグナル制御2018
    • Author(s)
      森 千夏、中木戸 誠、長門石 曉、津本 浩平
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] 金属プロテアーゼShhに対する抗体5E1の熱力学・速度論解析2018
    • Author(s)
      金田 生穂、長門石 曉、中木戸 誠、津本 浩平
    • Organizer
      第46回 構造活性相関シンポジウム
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] FcγR相互作用解析から広がる次世代医薬品開発2018
    • Author(s)
      津本浩平
    • Organizer
      第10回 GFRGプロジェクトシンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] 化膿連鎖球菌に対する抗菌剤開発を指向したヘム受容体-Hemoglobin間相互作用制御剤の探索2018
    • Author(s)
      妹尾 暁暢、長門石 曉、中山 登、坂東 泰彦、石崎 仁將、澤 竜一、五十嵐 雅之、津本 浩平
    • Organizer
      第12回バイオ関連化学シンポジウム
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] FcRカラムを用いた異なる細胞種由来IgGの糖鎖解析2018
    • Author(s)
      小菅 啓史、長門石 曉, 中木戸 誠, 黒田 大祐, 木吉 真人, 石井 明子, 寺尾 陽介, 朝岡 義晴, 大江 正剛, 井出 輝彦, 津本浩平
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] 微生物研究が拓く生命金属科学2018
    • Author(s)
      津本浩平
    • Organizer
      東京大学微生物科学イノベーション連携研究機構　発足記念シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] 分子シミュレーションと物理化学解析による抗体の熱安定性に関する研究2018
    • Author(s)
      河上恵理、黒田大祐、中木戸誠、津本浩平
    • Organizer
      日本化学会第98春季年会2018
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] 肝がん細胞に発現するROBO1抗原に対する二重特異性抗体の開発2018
    • Author(s)
      渡邉 裕治、中木戸 誠、長門石 曉、浜窪 隆雄、津本 浩平
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] 抗体の阻害機構解明や親和性向上設計のための熱測定2018
    • Author(s)
      長門石曉、津本浩平
    • Organizer
      第18回日本蛋白質学会年会
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] Nanodiscを用いたリン脂質二重膜環境中におけるヒトセロトニン受容体の機能解析2018
    • Author(s)
      吉田 浩平、黒田 大祐、長門石 曉、津本 浩平
    • Organizer
      第56回日本生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] Structural, physicochemical and computational analysis to reveal the mechanism of recognition of phosphorylated antigen by an antibody2018
    • Author(s)
      KAWADE, Raiji、AKIBA, Hiroki; NAKAKIDO, Makoto; KURODA, Daisuke; MARUYAMA, Toshiaki; OKUMURA, Shigeru; ENTZMINGER, Kevin; CAAVEIRO, Jose; TSUMOTO, Kouhei
    • Organizer
      日本化学会第98春季年会2018
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] 蛋白質-リガンド, 抗原-抗体相互作用解析における熱分析の活用2018
    • Author(s)
      長門石曉、津本浩平
    • Organizer
      熱測定スプリングスクール2019
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] SAXS及びITCによるホモ二量体形成蛋白質LI-cadherinの物性解析2018
    • Author(s)
      由井 杏奈、菊池 智佳、郷田 秀一郎、工藤 翔太、秋葉 宏樹、中木戸 誠、長門石 曉、新井 修、岩成 宏子、浜窪 隆雄、津本 浩平
    • Organizer
      第18回日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] Regulation of collagen fibril formation and stabilization by leucine rich repeat protein, OMD2018
    • Author(s)
      中木戸 誠、田島卓実、長門石曉、大沼信一、津本浩平
    • Organizer
      第18回日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] 転写調節因子PRDM14の天然変性領域とEED間における物理化学的相互作用解析2018
    • Author(s)
      大西 亮輔、長門石 曉、谷口 博昭、津本 浩平
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] 抗体によるリン酸基認識機構の結晶構造と熱力学的手法による解析2017
    • Author(s)
      河出 来時、秋葉 宏樹、奥村 繁、丸山 俊昭、K. Entzminger、津本 浩平
    • Organizer
      日本化学会第97春季年会
    • Place of Presentation
      慶應義塾大学日吉キャンパス(横浜市)
    • Year and Date
      2017-03-18
    • Data Source
      KAKENHI-PROJECT-24000011

  • [Presentation] ヒストンの血管内皮細胞障害を阻害するPTX3の凝集パターン解析2017
    • Author(s)
      早田 敬太、中木戸 誠、太期 健二、高松 佑一郎、山下 雄史、岩成 宏子、津本 浩平、浜窪 隆雄
    • Organizer
      2017年度生命科学系会合同年次大会
    • Data Source
      KAKENHI-PROJECT-25220205

  • [Presentation] 結晶構造と変異導入解析によるウサギ抗体のリン酸基認識機構の解明2017
    • Author(s)
      河出 来時、秋葉 宏樹、カアベイロ ホセ、奥村 繁、丸山 俊昭、Kevin Entzminger 、 津本 浩平
    • Organizer
      第17回日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] 抗原ペプチドの硫酸化がペプチドー抗体間相互作用に与える影響の熱力学的解析2017
    • Author(s)
      宮鍋 一紘、秋葉 宏樹、高松 佑一郎、山下 雄史、カアベイロ ホセ、津本 浩平
    • Organizer
      第55回日本生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-25000006

  • [Presentation] 抗アミロイドβ単鎖抗体発現mRNA搭載ナノミセルを用いたアルツハイマー病治療2017
    • Author(s)
      内田智士、F. Perche、秋葉宏樹、位髙啓史、津本浩平、片岡一則
    • Organizer
      第33回DDS学会学術大会
    • Data Source
      KAKENHI-PROJECT-25000006

  • [Presentation] Thermodynamic analysis of the recognition of a flexible peptide by an antibody2017
    • Author(s)
      Kouichi Miyanabe, Hiroki Akiba, Jose M. Caaveiro, Disuke Kuroda, Kouhei Tsumoto
    • Organizer
      日本化学会第97春季年会(2017)
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] 抗体によるリン酸基認識機構の結晶構造と熱力学的手法による解析2017
    • Author(s)
      河出来時、秋葉宏樹、カアベイロホセ、奥村繁、丸山俊昭、Kevin Entzminger , 津本浩平
    • Organizer
      日本化学会第97春季年会(2017)
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] Recent　progress the analytical solutions for bio-pharmacentics2017
    • Author(s)
      津本浩平
    • Organizer
      APPA2017
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] Development of SpyTag-based bispecific antibodies as two-step targeting agents2017
    • Author(s)
      Hiroki Akiba ,Kyohei Yumura, Kensuke Takayanagi, Takao Hamakubo, Kouhei Tsumoto
    • Organizer
      11th Annual Symposium on Nanobiotechnology 2017
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] 蛋白質相互作用の熱力学解析と創薬2017
    • Author(s)
      津本浩平, 長門石曉
    • Organizer
      日本ケミカルバイオロジー学会第12回年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] Thermodynamic effects of intramolcular hydrogen bonds within peptide on the peptide-antibody interaction2017
    • Author(s)
      Kazuhiro Miyanabe, Hiroki Akiba, Jose Caaveiro, Makoto Nakakido, Daisuke Kuroda, Kouhei Tsumoto
    • Organizer
      11th Annual Symposium on Nanobiotechnology 2017
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] Specificity-determining structural elements of antibody against antigen2017
    • Author(s)
      Hiroki Akiba, Ryosuke Yoshida, Raiji Kawade, Jose M. Caaveiro, Kouhei Tsumoto
    • Organizer
      日本化学会第97春季年会(2017)
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] 蛋白質相互作用の物理化学解析に基づくリガンドスクリーニング2017
    • Author(s)
      津本浩平, 長門石曉
    • Organizer
      日本化学会第98春季年会2018
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] hermodynamic elucidation of binding process for protein-ligand interactions to propose a drug design2017
    • Author(s)
      Satoru Nagatoishi, Kouhei Tsumoto
    • Organizer
      第55回日本生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] ホモ2量体形成蛋白質P-cadherinを標的とした蛋白質間相互作用阻害剤の探索2017
    • Author(s)
      妹尾暁暢、田島卓実、工藤翔太、長門石曉、津本浩平
    • Organizer
      2017年度生命科学系学会合同年次大会
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] mRNA搭載ナノミセルを用いた抗アミロイドβ単鎖抗体導入によるアルツハイマー病治療2017
    • Author(s)
      内田智士、F. Perche、秋葉宏樹、位髙啓史、津本浩平、片岡一則
    • Organizer
      日本核酸医薬学会第3回年会
    • Data Source
      KAKENHI-PROJECT-25000006

  • [Presentation] LI-cadherinのホモダイマー形成の細胞アッセイ及び物理化学的手法による分析2017
    • Author(s)
      由井杏奈、菊池智佳、工藤翔太、秋葉宏樹、長門石曉、新井修、岩成宏子、浜窪隆雄、津本浩平
    • Organizer
      日本化学会第97春季年会(2017)
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] 抗原ペプチドの硫酸化がペプチド－抗体間相互作用に与える影響の熱力学的解析2017
    • Author(s)
      宮鍋 一紘、秋葉 宏樹、高松 佑一郎、 山下 雄史、カアベイロ ホセ、津本 浩平
    • Organizer
      第55回日本生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] 物理化学的アプローチによる蛋白質間相互作用阻害剤の探索2017
    • Author(s)
      長門石曉, 津本浩平
    • Organizer
      第65回質量分析総合討論会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] シクロオレフィンポリマーCOP表面に対するホフマイスター効果に依存したタンパク質吸着制御2017
    • Author(s)
      長門石曉、藤田梨紗子、足達慧、西岡寛哉、二宮英隆、彼谷高敏、高井まどか、津本浩平
    • Organizer
      第11回バイオ関連化学シンポジウム
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] Recent Analytical Solutions for Bio-pharmaceutical Practice2017
    • Author(s)
      津本浩平
    • Organizer
      PITCON 2018
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] 結晶構造と変異導入解析によるウサギ抗体のリン酸基認識機構の解明2017
    • Author(s)
      河出 来時、秋葉 宏樹、カアベイロ ホセ、奥村 繁、丸山 俊昭、Kevin Entzminger、津本 浩平
    • Organizer
      第17回日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-25000006

  • [Presentation] 分析技術が拓く次世代バイオ医薬品開発研究2017
    • Author(s)
      津本浩平
    • Organizer
      一般社団法人日本分析機器工業会, 日本科学機器協会 / JASIS 2017
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] 低分子創薬の技術開発における物理化学バリデーション2017
    • Author(s)
      長門石曉、津本浩平
    • Organizer
      第30回バイオメディカル分析科学シンポジウム
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] 天然変性蛋白質Mint3とFIH-1の相互作用解析におけるH/D交換質量分析法の適用2017
    • Author(s)
      展 天承、中山 佳昭、長門石 曉、坂本 毅治、清木 元治、津本 浩平
    • Organizer
      第65回質量分析総合討論会
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] 抗原配列の硫酸化が抗体との相互作用に与える影響の熱力学的解析2017
    • Author(s)
      宮鍋一紘、秋葉宏樹、カアベイロホセ、黒田大祐、中木戸誠、高松佑一郎、山下雄史、津本浩平
    • Organizer
      第11回バイオ関連化学シンポジウム
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] 蛋白質相互作用解析が拓く革新的次世代創薬2017
    • Author(s)
      津本浩平
    • Organizer
      第15回RCGMフロンティアシンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] Thermodynamic analysis of the effect of sulfation on a peptide-antibody interaction2017
    • Author(s)
      宮鍋一紘、秋葉宏樹、高松佑一郎、山下雄史、カアベイロホセ、津本浩平
    • Organizer
      第55回日本生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] 次世代の低分子創薬を拓く蛋白質-低分子間相互作用の物理化学的解析2017
    • Author(s)
      長門石 曉、カアベイロホセ、津本浩平
    • Organizer
      日本薬学会第137年会
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] 熱分析から低分子薬剤の探索・設計に挑む2017
    • Author(s)
      長門石曉, Caaveiro Jose,　津本浩平
    • Organizer
      第30回九州分析化学若手の会 春の講演会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] Lipids as structural elements in pore formation2016
    • Author(s)
      Koldo Morante, Kouji Tanaka, Jose M. Caaveiro, Kouhei Tsumoto
    • Organizer
      IMI translocation 2016 - Novel approaches to fight bacteria
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] Thermodynamic analysis of molecular recognition between tea catechins and human serum albumin2016
    • Author(s)
      Tomoya Takahashi, Sartoru Nagatoishi, Daisuke Kuroda, Kouhei Tsumoto
    • Organizer
      CALCON2016
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] Biophysical approach to find the inhibitors of CapF and ERK2 enzyme in FBDD2016
    • Author(s)
      Satoru Nagatoishi, Kouhei Tsumoto
    • Organizer
      JCUP VII
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] 抗金属錯体抗体と多種の金属錯体との相互作用における親和性創出基盤2016
    • Author(s)
      秋葉 宏樹、吉田 良介、カアベイロ ホセ、津本 浩平
    • Organizer
      第16回 日本蛋白質科学会年会
    • Place of Presentation
      福岡国際会議場(福岡市)
    • Year and Date
      2016-06-09
    • Data Source
      KAKENHI-PROJECT-24000011

  • [Presentation] コラーゲン線維形成プロセスを制御する蛋白質Osteomodulinの制御機構解析2016
    • Author(s)
      田島卓実、長門石暁、カアベイロホセ、中木戸誠、相良洋、大沼信一、津本浩平
    • Organizer
      第10回バイオ関連化学シンポジウム
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] 次世代抗体開発を指向したin silicoとin vitroをつなぐ熱力学解析2016
    • Author(s)
      長門石曉、津本浩平
    • Organizer
      バイオプロセス講演会
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] 疾患治療を目的とした抗PRELP抗体の結合特性の解明2016
    • Author(s)
      野中 桃子、田島 卓実、長門石 曉、岩成 宏子、浜窪 隆雄、大沼 信一、津本 浩平
    • Organizer
      第32回 日本DDS学会学術集会
    • Place of Presentation
      グランシップ(静岡市)
    • Year and Date
      2016-06-30
    • Data Source
      KAKENHI-PROJECT-24000011

  • [Presentation] 次世代薬剤設計を指向した蛋白質－低分子間相互作用のプロセス熱力学2016
    • Author(s)
      長門石曉、 山口奏、津本浩平
    • Organizer
      第10回バイオ関連化学シンポジウム
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] リン酸化ペプチドを抗原とするウサギIgGとscFvについての熱力学的手法を用いた物理化学解析2016
    • Author(s)
      河出 来時、秋葉 宏樹、奥村 繁、丸山 俊昭、K. Entzminger、津本 浩平
    • Organizer
      第16回 日本蛋白質科学会年会
    • Place of Presentation
      福岡国際会議場(福岡市)
    • Year and Date
      2016-06-09
    • Data Source
      KAKENHI-PROJECT-24000011

  • [Presentation] SPR and ITC-based small-molecule screening to find inhibitors of protein-protein interaction2016
    • Author(s)
      Satoru Nagatoishi, Kouhei Tsumoto
    • Organizer
      DiPIA 2016
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] Basis of cell-membrane damage by a protein nanopore2016
    • Author(s)
      Jose M.M. Caaveiro、Koji Tanaka、Koldo Morante、Kouhei Tsumoto
    • Organizer
      Todai-Tsinghua Joint Workshop for Frontiers in Bioengineering and Biomedical Engineering
    • Place of Presentation
      東京大学（東京都文京区）
    • Year and Date
      2016-03-10
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25249115

  • [Presentation] ドラッグデリバリーを指向した二重特異性抗体の抗原上形成2016
    • Author(s)
      秋葉 宏樹、高柳 憲介、湯村 恭平、浜窪 隆雄、津本 浩平
    • Organizer
      第10回 バイオ関連化学シンポジウム
    • Place of Presentation
      石川県立音楽堂、もてなしドーム地下イベント広場(金沢市)
    • Year and Date
      2016-09-08
    • Data Source
      KAKENHI-PROJECT-24000011

  • [Presentation] How we can improve affinity of antibodies for the targets towards therapeutics2016
    • Author(s)
      Kouhei Tsumoto
    • Organizer
      CALCON2016
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] Thermodynamics of the interaction between proteins and small compounds in drug discovery2016
    • Author(s)
      長門石曉、津本浩平
    • Organizer
      分子研研究会
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] 9F NMR and SPR Screening for the Development of an Inhibitor of the Tob1-CNOT7 Interaction2016
    • Author(s)
      Kouhei Soeda ,Satoru Nagatoishi, E. Kato, M. Yamamoto, Kouhei Tsumoto
    • Organizer
      The 27th International Conference on Magnetic Resonance in Biological Systems
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] 熱力学的解析を基盤とした茶カテキン-蛋白質間の分子認識機構の解明2016
    • Author(s)
      高橋知也、長門石曉、黒田大祐、津本浩平
    • Organizer
      第21回日本フードファクター学会学術集会
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] 合理的設計指針構築を目指したVHH抗原相互作用機構解析2016
    • Author(s)
      田村 浩子、木吉 真人、秋葉 宏樹、カアベイロ ホセ、津本 浩平
    • Organizer
      第32回 日本DDS学会学術集会
    • Place of Presentation
      グランシップ(静岡市)
    • Year and Date
      2016-06-30
    • Data Source
      KAKENHI-PROJECT-24000011

  • [Presentation] 抗ペプチド抗体による抗原ペプチド構造の認識機構の解明2016
    • Author(s)
      宮鍋 一紘、秋葉 宏樹、カアベイロ ホセ、黒田 大祐、中木戸 誠、新井 修、岩成 宏子、浜窪 隆雄、津本 浩平
    • Organizer
      第16回 日本蛋白質科学会年会
    • Place of Presentation
      福岡国際会議場(福岡市)
    • Year and Date
      2016-06-08
    • Data Source
      KAKENHI-PROJECT-24000011

  • [Presentation] Thermodynamic analysis of molecular recognition between tea catechins and human serum albumin2016
    • Author(s)
      Sartoru Nagatoishi, Y. Tanabe, Kouhei Tsumoto
    • Organizer
      CALCON2016
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02420

  • [Presentation] Lipid-protein partnering during pore-formation of fragaceatoxinC2016
    • Author(s)
      Koldo Morante、Jose M.M. Caaveiro、Koji Tanaka、Kouhei Tsumoto
    • Organizer
      The Biophysical Society 60th Annual Meeting
    • Place of Presentation
      Los Angeles（U.S.A.）
    • Year and Date
      2016-02-28
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25249115

  • [Presentation] Cell adhesion of human P-cadherin regulated by a Self-Chaperone mechanism2015
    • Author(s)
      Shota Kudo、Jose M.M. Caaveiro、Kouhei Tsumoto
    • Organizer
      9th Retreat Meeting of the IMSUT
    • Place of Presentation
      東京大学検見川セミナーハウス（千葉県千葉市花見川区）
    • Year and Date
      2015-10-29
    • Data Source
      KAKENHI-PROJECT-25249115

  • [Presentation] 抗DOTA金属錯体抗体の一本鎖化とその分子認識メカニズムの解明2015
    • Author(s)
      秋葉 宏樹、吉田 良介、カアベイロ ホセ、津本 浩平
    • Organizer
      日本分子イメージング学会第１０回学術集会
    • Place of Presentation
      タワーホール船堀（東京都江戸川区）
    • Year and Date
      2015-05-21
    • Data Source
      KAKENHI-PROJECT-25249115

  • [Presentation] Intravital imaging of drug delivery systems2015
    • Author(s)
      Y. Matsumoto
    • Organizer
      2015 Conference on developmental Biology Scientific & Drug Delivery System Program
    • Place of Presentation
      Academia Sinica (Taipei, Taiwan)
    • Year and Date
      2015-11-10
    • Description
      【発表確定】
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25000006

  • [Presentation] 自己組織化を利用したDDSのための改変抗体の作製2015
    • Author(s)
      高柳憲介, 湯村恭平, 秋葉宏樹, 松長遼, 浜窪隆雄, 津本浩平
    • Organizer
      第31回日本DDS学会学術集会
    • Place of Presentation
      京王プラザホテル(東京都新宿区)
    • Year and Date
      2015-07-03
    • Description
      【発表確定】
    • Data Source
      KAKENHI-PROJECT-25000006

  • [Presentation] 膜孔形成毒素の自己組織化に生体膜の組成とダイナミクスが与える影響の分子基盤2015
    • Author(s)
      津本 浩平 (代理:田中 耕路)、カアベイロ ホセ
    • Organizer
      第５３回日本生物物理学会年会
    • Place of Presentation
      金沢大学角間キャンパス（石川県金沢市）
    • Year and Date
      2015-09-14
    • Data Source
      KAKENHI-PROJECT-25249115

  • [Presentation] The protein-protein interactions in highly concentrated antibody solution investigated by Raman spectroscopy．2015
    • Author(s)
      太田 周志、長門石 曉、野口 慎太郎、津本 浩平
    • Organizer
      第５３回日本生物物理学会年会
    • Place of Presentation
      金沢大学角間キャンパス（石川県金沢市）
    • Year and Date
      2015-09-13
    • Data Source
      KAKENHI-PROJECT-25249115

  • [Presentation] 抗リゾチームシングルドメイン抗体の抗原認識における熱力学的特性2015
    • Author(s)
      秋葉 宏樹、田村 浩子、木吉 真人、カアベイロ ホセ、津本 浩平
    • Organizer
      第９回バイオ関連化学シンポジウム
    • Place of Presentation
      熊本大学（熊本県熊本市）
    • Year and Date
      2015-09-10
    • Data Source
      KAKENHI-PROJECT-25249115

  • [Presentation] 金属イオンデリバリーのための抗金属錯体一本鎖抗体の開発とその性質解析2015
    • Author(s)
      秋葉 宏樹、吉田 良介、カアベイロ ホセ、津本 浩平
    • Organizer
      第３１回日本ＤＤＳ学会学術集会
    • Place of Presentation
      京王プラザホテル（東京都新宿区）
    • Year and Date
      2015-07-02
    • Data Source
      KAKENHI-PROJECT-25249115

  • [Presentation] Biophysical cross-validation in fragment screening of fluorinated chemical library toward FBDD using SPR, ITC and 19F NMR2015
    • Author(s)
      Satoru Nagatoishi、Sou Yamaguchi、Keita Kajita、Etsuko Katoh、Hiroyuki Akiyama、Satoru Kanai、Toshio Furuya、Kouhei Tsumoto
    • Organizer
      The 43rd Symposium on Structural Activity Relationship 2015 The 10th Japan-China Joint Symposium on Drug Discovery and Development
    • Place of Presentation
      新潟日報メディアシップ日報ホール（新潟県新潟市）
    • Year and Date
      2015-09-28
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25249115

  • [Presentation] Mechanism of self-assembly of a transmembrane pore triggered by specific biomembranes2015
    • Author(s)
      Koji Tanaka、Jose Caaveiro、Koldo Morante、Kouhei Tsumoto
    • Organizer
      The International Chemical Congress of Pacific Basin Societies 2015 (PacificChem)
    • Place of Presentation
      Honolulu, Hawaii（U.S.A.）
    • Year and Date
      2015-12-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25249115

  • [Presentation] ドラッグデリバリーを指向した抗ペプチド抗体作製および抗原ペプチド融合蛋白質との相互作用解析2015
    • Author(s)
      宮鍋一紘, 秋葉宏樹, カアベイロホセ, 中木戸誠, 岩成宏子, 新井修, 浜窪隆雄, 津本浩平
    • Organizer
      第31回日本DDS学会学術集会
    • Place of Presentation
      京王プラザホテル(東京都新宿区)
    • Year and Date
      2015-07-02
    • Description
      【発表確定】
    • Data Source
      KAKENHI-PROJECT-25000006

  • [Presentation] Development of enzyme-loaded polyion complex vesicles for in vivo nanoreactor2015
    • Author(s)
      Y. Anraku, M. Kamiya, S. Tanaka, T. Nomoto, K. Toh, Y. Matsumoto, S. Fukushima, D. Sueyoshi, A. Kishimura, M. Kano, Y. Urano, N. Nishiyama, K. Kataoka
    • Organizer
      THE INTERNATIONAL CHEMICAL CONGRESS OF PACIFIC BASIN SOCIETIES (PACIFICHEM2015)
    • Place of Presentation
      Hawaii Convention Center (Hawaii, USA)
    • Year and Date
      2015-12-15
    • Description
      【発表確定】
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25000006

  • [Presentation] 抗EDTA抗体CHA255scFvの抗原認識機構解析2015
    • Author(s)
      吉田良介, 秋葉宏樹, 津本浩平
    • Organizer
      第95回日本化学会年会
    • Place of Presentation
      日本大学理工学部船橋キャンパス(千葉県船橋市)
    • Year and Date
      2015-03-26
    • Data Source
      KAKENHI-PROJECT-25000006

  • [Presentation] Structural and mechanistic basis of capsular polysaccharide-synthesizing enzymes CapE/CapF, and the route to discovery novel inhibitors with antibacterial properties2015
    • Author(s)
      Jose M.M. Caaveiro、Takamistsu Miyafusa、Takeru Chigira、Koichiro Nakano、Satoru Nagatoishi、Kouhei Tsumoto
    • Organizer
      The International Chemical Congress of Pacific Basin Societies 2015 (PacificChem)
    • Place of Presentation
      Honolulu, Hawaii（U.S.A.）
    • Year and Date
      2015-12-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25249115

  • [Presentation] 溶液中の動態から示される難溶性蛋白質KAP8.1の構造と機能2014
    • Author(s)
      ガンバットジャホラン、松長遼、秋葉宏樹、下村裕、新井修、岩成宏子、浜窪隆雄、津本浩平
    • Organizer
      日本化学会第94春季年会
    • Place of Presentation
      名古屋大学(愛知県名古屋市)
    • Year and Date
      2014-03-28
    • Data Source
      KAKENHI-PROJECT-24000011

  • [Presentation] 抗DOTA単鎖抗体の抗原認識における金属イオンの効果2014
    • Author(s)
      秋葉宏樹、吉田良介、津本浩平
    • Organizer
      日本化学会第94春季年会
    • Place of Presentation
      名古屋大学(愛知県名古屋市)
    • Year and Date
      2014-03-27
    • Data Source
      KAKENHI-PROJECT-24000011

  • [Presentation] プロテオグリカンOsteomodulinの物理化学的解析2014
    • Author(s)
      田島卓実、中木戸誠、長門石曉、大沼信一、津本浩平
    • Organizer
      日本化学会第94春季年会
    • Place of Presentation
      名古屋大学(愛知県名古屋市)
    • Year and Date
      2014-03-29
    • Data Source
      KAKENHI-PROJECT-24000011

  • [Presentation] 抗原ペプチドへの蛋白質融合が抗原－抗体相互作用に及ぼす影響の熱力学的評価2014
    • Author(s)
      宮鍋 一紘、秋葉 宏樹、中木戸 誠、新井 修、岩成 宏子、浜窪 隆雄、津本 浩平
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      京都
    • Year and Date
      2014-10-16
    • Data Source
      KAKENHI-PROJECT-25220205

  • [Presentation] 抗原ペプチドへの蛋白質融合が抗原-抗体相互作用に及ぼす影響の熱力学的評価2014
    • Author(s)
      宮鍋一紘、秋葉宏樹、中木戸誠、新井修、岩成宏子、浜窪隆雄、津本浩平
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      国立京都国際会館(京都市)
    • Year and Date
      2014-10-16
    • Description
      【発表確定】
    • Data Source
      KAKENHI-PROJECT-24000011

  • [Presentation] Structural analysis of the pore-forming tosin FraC with multiple lipids bound2014
    • Author(s)
      K. Tanaka, Jose M. M. Caaveiro, Koldo Morante, Juan Manuel Gonzalez-Manas, K. Tsumoto
    • Organizer
      Biophysical Society 58th Annual Meeting
    • Place of Presentation
      Moscone Center (San Francisco, California, USA
    • Year and Date
      2014-02-18
    • Data Source
      KAKENHI-PROJECT-25000006

  • [Presentation] プレターゲティング法を目指した低免疫原性化コアストレプトアビジン融合抗体の開発2014
    • Author(s)
      秋葉宏樹, 湯村恭平, 宇井美穂子, 土居洋文, 杉山暁, 浜窪隆雄, 児玉龍彦, 津本浩平
    • Organizer
      第30回日本DDS学会学術集会
    • Place of Presentation
      慶應義塾大学(東京都港区)
    • Year and Date
      2014-07-30
    • Data Source
      KAKENHI-PROJECT-25000006

  • [Presentation] 抗DOTA一本鎖抗体のDOTA認識機構の熱力学と構造による解明2014
    • Author(s)
      吉田良介, 秋葉宏樹, 津本浩平
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      国立京都国際会館(京都府京都市)
    • Year and Date
      2014-10-15
    • Data Source
      KAKENHI-PROJECT-25000006

  • [Presentation] プレターゲティング法を目指した低免疫原性化コアストレプトアビジン融合抗体の開発2014
    • Author(s)
      秋葉宏樹、湯村恭平、宇井美穂子、土居洋文、杉山暁、浜窪隆雄、児玉龍彦、津本浩平
    • Organizer
      第30回日本DDS学会学術集会
    • Place of Presentation
      慶応義塾大学薬学部芝共立キャンパス
    • Year and Date
      2014-07-30
    • Description
      【発表確定】
    • Data Source
      KAKENHI-PROJECT-24000011

  • [Presentation] 高機能性抗体の設計に向けた抗P-cadherin抗体の物性、構造解析2014
    • Author(s)
      工藤翔太、Caaveiro Jose、長門石曉、浜窪隆雄、児玉龍彦、松浦正、須藤幸夫、津本浩平
    • Organizer
      第12回次世代を担う若手のためのフィジカル・ファーマフォーラム
    • Place of Presentation
      箱根高原ホテル
    • Year and Date
      2014-07-14
    • Description
      【発表確定】
    • Data Source
      KAKENHI-PROJECT-24000011

  • [Presentation] 多機能性タンパク質PHB2の物性解析2014
    • Author(s)
      千吉良岳、長門石曉、片桐豊雅、津本浩平
    • Organizer
      日本化学会第94春季年会
    • Place of Presentation
      名古屋大学(愛知県名古屋市)
    • Year and Date
      2014-03-29
    • Data Source
      KAKENHI-PROJECT-24000011

  • [Presentation] 生命分子相互作用解析 : ITCとSPR2014
    • Author(s)
      長門石曉、津本浩平
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本大学(熊本)
    • Year and Date
      2014-03-30
    • Invited
    • Data Source
      KAKENHI-PROJECT-24000011

  • [Presentation] 抗DOTA一本鎖抗体のDOTA認識機構の熱力学と構造による解明2014
    • Author(s)
      吉田良介、秋葉宏樹、津本浩平
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      国立京都国際会館(京都市)
    • Year and Date
      2014-10-17
    • Description
      【発表確定】
    • Data Source
      KAKENHI-PROJECT-24000011

  • [Presentation] 難溶性蛋白質KAP8.1の溶液状態と粉末状態の多面的な解析による特徴付け2014
    • Author(s)
      Ganbat Javkhlan、松長 遼、秋葉 宏樹、下村 裕、新井 修、岩成 宏子、浜窪 隆雄、津本 浩平
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      京都
    • Year and Date
      2014-10-16
    • Data Source
      KAKENHI-PROJECT-25220205

  • [Presentation] STRUCTURAL ANALYSIS OF THE PORE-FORMING TOXIN FRAC WITH MULTIPLE LIPIDS BOUND.2014
    • Author(s)
      Koji Tanaka, Jose M. M. Caaveiro, Koldo Morante, Juan Manuel Gonzalez-Manas, Kouhie Tsumoto
    • Organizer
      Biophysical Society 58th Annual Meeting
    • Place of Presentation
      Moscone Center (アメリカ合衆国/カリフォルニア州)
    • Year and Date
      2014-02-15
    • Data Source
      KAKENHI-PROJECT-25249115

  • [Presentation] 荷電性アミノ酸の導入による高親和性抗体の合理的分子設計2014
    • Author(s)
      木吉真人、Caaveiro Jose、三浦恵梨、長門石曉、中木戸誠、曽我真司、白井宏樹、川畑茂樹、中村春木、津本浩平
    • Organizer
      第30回日本DDS学会学術集会
    • Place of Presentation
      慶応義塾大学薬学部芝共立キャンパス
    • Year and Date
      2014-07-31
    • Description
      【発表確定】
    • Data Source
      KAKENHI-PROJECT-24000011

  • [Presentation] Tethering PEG density on polyplex micelles and stealthiness in blood circulation2013
    • Author(s)
      K. Osada, T. A. Tockary, Q. Chen, A. Dirisala, K. Machitani, T. Nomoto, Y. Matsumoto, K. Kataoka
    • Organizer
      40th Annual Meeting & Exposition of the Controlled Release Society
    • Place of Presentation
      Hawaii Convention Center (Honolulu, Hawaii, USA)
    • Year and Date
      2013-07-21
    • Data Source
      KAKENHI-PROJECT-25000006

  • [Presentation] 分子間相互作用をミクロに捕らえる表面プラズモン共鳴法と熱測定の活用2013
    • Author(s)
      長門石曉、津本浩平
    • Organizer
      第17回コロイド・界面フォーラム
    • Place of Presentation
      KKR江の島ニュー向洋(神奈川県藤沢市)
    • Year and Date
      2013-07-18
    • Data Source
      KAKENHI-PROJECT-24000011

  • [Presentation] Analysis of hypo-immunogenic core streptavidin and construction of fusion-an2013
    • Author(s)
      湯村恭平, 宇井美穂子、土居洋文、杉山暁、浜窪隆雄、児玉龍彦、津本浩平
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2013-09-13
    • Data Source
      KAKENHI-PROJECT-24000011

  • [Presentation] フラグメントライブラリーによる莢膜合成酵素CapFの阻害剤探索2013
    • Author(s)
      中納広一郎、宮房孝光、長門石曉、Jose Caaveiro、津本浩平
    • Organizer
      第４回スクリーニング学研究会
    • Place of Presentation
      東京大学伊藤謝恩ホール(東京都文京区)
    • Year and Date
      2013-11-29
    • Data Source
      KAKENHI-PROJECT-25249115

  • [Presentation] 希土類錯体によるペプチド・蛋白質のチロシンリン酸化検出法の構築2013
    • Author(s)
      秋葉宏樹、須磨岡淳、浜窪隆雄、津本浩平、小宮山眞
    • Organizer
      第7回バイオ関連化学シンポジウム
    • Place of Presentation
      名古屋大学(愛知県名古屋市)
    • Year and Date
      2013-09-28
    • Data Source
      KAKENHI-PROJECT-24000011

  • [Presentation] 親和性向上を目指した抗インターフェロンγレセプター抗体の合理的改変2013
    • Author(s)
      木吉真人, 三浦恵理、長門石曉、Jose M. M. Caaveiro M. M、中木戸誠、曽我真司、白井宏樹、河畑茂樹、中村春木、津本浩平
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2013-09-13
    • Data Source
      KAKENHI-PROJECT-24000011

  • [Presentation] Protein shackle : A polymerizing scaffold for functional protein2013
    • Author(s)
      R. Matsunaga, S. Nagatoishi, K. Tsumoto
    • Organizer
      5th Annual PEGS Europe
    • Place of Presentation
      Sheraton Lisboa Hotel & Spa (Lisbon, Portugal)
    • Year and Date
      2013-11-04
    • Data Source
      KAKENHI-PROJECT-25000006

  • [Presentation] Actinoporin, FraCは二つの異なる基質-脂質と糖鎖を一つのポケットで認識する2013
    • Author(s)
      田中 耕路、Jose M. M. Caaveiro, 津本浩平
    • Organizer
      第60回トキシンシンポジウム
    • Place of Presentation
      楓香荘(兵庫県宍粟市)
    • Year and Date
      2013-07-17
    • Data Source
      KAKENHI-PROJECT-24000011

  • [Presentation] DDS evaluation using intravital real-time laser scanning confocal microscopy2013
    • Author(s)
      Y. Matsumoto, T. Nomoto, K. Toh, N. Nishiyama, T. Yamasoba, K. Kataoka
    • Organizer
      40th Annual Meeting & Exposition of the Controlled Release Society
    • Place of Presentation
      Hawaii Convention Center (Honolulu, Hawaii, USA)
    • Year and Date
      2013-07-21
    • Data Source
      KAKENHI-PROJECT-25000006

  • [Presentation] 分子間相互作用をミクロに捕らえる表面プラズモン共鳴法と熱測定の活用2013
    • Author(s)
      長門石曉、津本浩平
    • Organizer
      第17回コロイド・界面フォーラム
    • Place of Presentation
      KKR江の島ニュー向洋(神奈川県藤沢市）
    • Year and Date
      2013-07-18
    • Invited
    • Data Source
      KAKENHI-PROJECT-25249115

  • [Presentation] 低免疫原性化コアストレプトアビジンを用いた融合抗体の構築と解析2013
    • Author(s)
      湯村 恭平,宇井 美穂子,土居 洋文,杉山 暁,浜窪 隆雄,児玉 龍彦,津本 浩平
    • Organizer
      第36回日本分子生物学会
    • Place of Presentation
      神戸
    • Year and Date
      2013-12-03
    • Data Source
      KAKENHI-PROJECT-25220205

  • [Presentation] FraCの生体膜上での自己組織化は脂質ドメインの形成により促進される2013
    • Author(s)
      田中耕路, Koldo Morante, Jose M. M. Caaveiro, J. M. Gonzalez-Manas, 津本浩平
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2013-09-11
    • Data Source
      KAKENHI-PROJECT-24000011

  • [Presentation] 病原性細菌のHeme輸送システムを阻害する低分子化合物の探索2013
    • Author(s)
      長門石曉、下村拓矢、安部良太、星野将人、Jose Caaveiro、津本浩平
    • Organizer
      第４回スクリーニング学研究会
    • Place of Presentation
      東京大学伊藤謝恩ホール(東京都文京区)
    • Year and Date
      2013-11-29
    • Data Source
      KAKENHI-PROJECT-25249115

  • [Presentation] 細胞接着蛋白質P-cadherinの同種親和的二量体形成機構の解明2013
    • Author(s)
      工藤 翔太,ホセ カアベイロ,長門石 暁,浜窪 隆雄,児玉 龍彦,松浦 正,須藤 幸夫,津本 浩平
    • Organizer
      第86回日本生化学学会大会
    • Place of Presentation
      横浜
    • Year and Date
      2013-09-12
    • Data Source
      KAKENHI-PROJECT-25220205

  • [Presentation] 天然変性型蛋白質の機能制御へ向けた核酸結合蛋白質YB-1の物理化学的解析2013
    • Author(s)
      長門石曉、田邊 裕美子、西方 敬人、杉本 直己、津本 浩平
    • Organizer
      第7回バイオ関連化学シンポジウム
    • Place of Presentation
      名古屋大学(愛知県名古屋市)
    • Year and Date
      2013-09-28
    • Data Source
      KAKENHI-PROJECT-24000011

  • [Presentation] 熱力学的相互作用解析と分子動力学シミュレーションによる抗体の親和性向上のメカニズムの研究2013
    • Author(s)
      渡部 貴大,長門石 曉,山下 雄史,中山 泰亮,溝端 栄一,浜窪 隆雄,井上 豪,津本 浩平,児玉 龍彦,藤谷 秀章
    • Organizer
      第36回日本分子生物学会
    • Place of Presentation
      神戸
    • Year and Date
      2013-12-03
    • Data Source
      KAKENHI-PROJECT-25220205

  • [Presentation] 細胞接着蛋白質P-cadherinの同種親和的二量体形成機構の解明2013
    • Author(s)
      工藤翔太、Jose M. M. Caaveiro、長門石曉、浜窪隆雄、児玉龍彦、松浦正、須藤幸夫、津本浩平
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2013-09-11
    • Data Source
      KAKENHI-PROJECT-24000011

  • [Presentation] Thermodynamic Analyses of Binding and Transfer of Heme : Isd System2011
    • Author(s)
      Tsumoto K, Caaveiro J. M. M., Abe R, Moriwaki Y, Vu N, Watanabe M, Tanaka Y
    • Organizer
      14th Asian Chemical Congress 2011(14ACC)
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Presentation] Structural and functional analysis of Capsular polysaccharide synthesizing enzyme CapF from Staphylococcus aureus2011
    • Author(s)
      Miyafusa T, Tanaka Y, Caaveiro J. M. M., Kuroda M, Yao M, Ohta T, Tanaka I, Tsumoto K
    • Organizer
      The IXth European Symposium of The Protein Society
    • Place of Presentation
      Stockholm-Stockholm University, Aula Magna
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Presentation] Targeted glycosylation of "non-core region" of Interleukin 11 modulates its biological function2011
    • Author(s)
      Yanaka S, Sano E, Naruse N, Caaveiro J. M. M., Tsumoto K
    • Organizer
      Immunology 2011
    • Place of Presentation
      Moscone Center(San Francisco・USA)
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Presentation] Structural and functional analysis of capsular polysaccharide synthesizing enzyme CapF2010
    • Author(s)
      T. Miyafusa ; Y. Tanaka ; J. Martinez Caaveiro ; M. Kuroda ; M. Yao ; T. Ohta ; I. Tanaka ; K. Tsumoto
    • Organizer
      2010環太平洋国際化学会
    • Place of Presentation
      ハワイコンベンションセンター
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Presentation] Hawaii Convention Centor Solubilization of Membrane Proteins with Novel N-Acylamino Acid Detergents2010
    • Author(s)
      安部良太・ホセマルチネスカアベイロ・津本浩平
    • Organizer
      Pacific Chem 2010
    • Place of Presentation
      米国ハワイ州
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Presentation] Aromatic Interactions are Essential for Carbohydrate Recognition by an Enzyme2010
    • Author(s)
      Caaveiro, J. M. M., Kobe, A., Clifton, J. G., Ringe, D., Petsko, G. A. and Tsumoto, K
    • Organizer
      DiPiA2010
    • Place of Presentation
      Skipper Hotel. Barcelona,スペイン
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Presentation] Three Hot-Spot Regions Define the High Affinity of Human Interleukin 15 for its Private alpha-Receptor2009
    • Author(s)
      Caaveiro, J. M. M., Sakamoto, S., Sano, E., Kudou, M. and Tsumoto, K
    • Organizer
      The 23rd Symposium of the Protein Society
    • Place of Presentation
      Boston, Massachusetts, USA
    • Data Source
      KAKENHI-PROJECT-21360398

  • [Presentation] 材料・医療への展開を目指した蛋白質相互作用解析2008
    • Author(s)
      津本
    • Organizer
      日本分析化学会東北支部会
    • Place of Presentation
      東北大学
    • Year and Date
      2008-03-22
    • Data Source
      KAKENHI-PROJECT-19021011

  • [Presentation] Protein Interaction Analyses for Materials and Medicines2008
    • Author(s)
      Tsumoto
    • Organizer
      10th Symposium on Biomolecular Chemistry
    • Place of Presentation
      Kumamoto
    • Year and Date
      2008-01-11
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Presentation] 「蛋白質相互作用解析:材料・医療への展開」2008
    • Author(s)
      津本
    • Organizer
      第10回日本化学会生命化学研究会シンポジウム
    • Place of Presentation
      熊本大学
    • Year and Date
      2008-01-11
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Presentation] Development of Materials and. Medicines based on Protein Interaction Analyses2008
    • Author(s)
      Tsumoto
    • Organizer
      Symposium on Analytical Chemistry
    • Place of Presentation
      Sendai
    • Year and Date
      2008-03-22
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Presentation] 「蛋白質相互作用解析:材料・医療への展開」2008
    • Author(s)
      津本
    • Organizer
      第10回日本化学会生命化学研究会シンポジウム
    • Place of Presentation
      熊本大学
    • Year and Date
      2008-01-11
    • Data Source
      KAKENHI-PROJECT-19021011

  • [Presentation] 材料・医療への展開を目指した蛋白質相互作用解析2008
    • Author(s)
      津本
    • Organizer
      日本分析化学会東北支部会
    • Place of Presentation
      東北大学
    • Year and Date
      2008-03-22
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Presentation] Role of Arginine in Handling Proteins.2007
    • Author(s)
      Tsumoto
    • Organizer
      第1回日本スイスケミカルバイオロジー会議
    • Place of Presentation
      スイスETH(ローザンヌ)
    • Year and Date
      2007-06-25
    • Data Source
      KAKENHI-PROJECT-19021011

  • [Presentation] Chromatography using Arginine : Antibodies2007
    • Author(s)
      Tsumoto
    • Organizer
      Symposium on Liquid Chromatographies
    • Place of Presentation
      Noda
    • Year and Date
      2007-06-29
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Presentation] Role of Arginine in Handling Proteins2007
    • Author(s)
      Tsumoto
    • Organizer
      第1回日本スイスケミカルバイオロジー会議
    • Place of Presentation
      スイスETH(ローザンヌ)
    • Year and Date
      2007-06-25
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Presentation] さらに進化した蛋白質相互作用の熱力学解析2007
    • Author(s)
      津本
    • Organizer
      第45回目本生物物理学会年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2007-12-21
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Presentation] Role of Arginine in Handing Proteins.2007
    • Author(s)
      Tsumoto
    • Organizer
      第1回日本イスケミカルバイオロジー会議
    • Place of Presentation
      スイスETH(ローザンヌ)
    • Year and Date
      2007-06-25
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Presentation] さらに進化した蛋白質相互作用の熱力学解析2007
    • Author(s)
      津本
    • Organizer
      第45回日本生物物理学会年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2007-12-21
    • Data Source
      KAKENHI-PROJECT-19021011

  • [Presentation] アルギニンを用いたクロマトグラフィー:抗体を中心に2007
    • Author(s)
      津本
    • Organizer
      第204回液体クロマトグラフィー研究懇談会
    • Place of Presentation
      東京理科大学
    • Year and Date
      2007-06-29
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Presentation] Role of Arginine in Protein Handling2007
    • Author(s)
      Tsumoto
    • Organizer
      1st Symposium on Swiss-Japan Chemical Biology Conference
    • Place of Presentation
      Swiss
    • Year and Date
      2007-06-25
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Presentation] Current status of cancer immunotherapy and its perspectives2007
    • Author(s)
      Tsumoto
    • Organizer
      Annual Meeting of Japan Cancer Society
    • Place of Presentation
      Yokohama
    • Year and Date
      2007-10-03
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Presentation] 癌免疫療法の現状と今後2007
    • Author(s)
      津本
    • Organizer
      日本癌学会シンポジウム
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2007-10-03
    • Data Source
      KAKENHI-PROJECT-19021011

  • [Presentation] さらに進化した蛋白質相互作用の熱力学解析2007
    • Author(s)
      津本
    • Organizer
      第45回日本生物物理学会年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2007-12-21
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Presentation] アルギニンを用いたクロマトグラフィー:抗体を中心に2007
    • Author(s)
      津本
    • Organizer
      第204回液体クロマトグラフィー研究懇談会
    • Place of Presentation
      東京理科大学
    • Year and Date
      2007-06-29
    • Data Source
      KAKENHI-PROJECT-19021011

  • [Presentation] Evolved Thermodynamic Analyses : Protein Interaction2007
    • Author(s)
      Tsumoto
    • Organizer
      Annual Meeting of Biophysics
    • Place of Presentation
      Yokohama
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Presentation] 癌免疫療法の現状と今後2007
    • Author(s)
      津本
    • Organizer
      日本癌学会シンポジウム
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2007-10-03
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17360393

  • [Presentation] Protein shackle: A polymerizing scaffold for functional protein
    • Author(s)
      Ryo Matsunaga, Satoru Nagatoishi, Kouhei Tsumoto
    • Organizer
      5th Annual PEGS Europe
    • Place of Presentation
      Sheraton Lisboa Hotel & Spa (ポルトガル/リスボン)
    • Year and Date
      2013-11-04 – 2013-11-08
    • Data Source
      KAKENHI-PROJECT-25249115

  • [Presentation] 化膿レンサ球菌由来Shr、Shpによるヘム輸送機構の物理化学的解析
    • Author(s)
      星野将人、Caaveiro Jose、長門石曉、中川一路、津本 浩平
    • Organizer
      第8回バイオ関連化学シンポジウム
    • Place of Presentation
      岡山大学(岡山県岡山市)
    • Year and Date
      2014-09-11 – 2014-09-13
    • Data Source
      KAKENHI-PROJECT-25249115

  • [Presentation] 構造情報に基づくDJ-1二量体形成へのC末端モチーフの寄与の解明
    • Author(s)
      田代晋也、Jose M. M. Caaveiro、森脇由隆、Shulin Ju、Quyen Hoang、津本浩平
    • Organizer
      第３６回分子生物学会
    • Place of Presentation
      神戸ポートアイランド(兵庫県神戸市)
    • Year and Date
      2013-12-03 – 2013-12-06
    • Data Source
      KAKENHI-PROJECT-25249115

  • [Presentation] 溶液中の動態から示される 難溶性蛋白質KAP8.1の構造と機能
    • Author(s)
      ガンバット ジャホラン、松長遼、秋葉宏樹、下村裕、新井修、 岩成宏子、浜窪隆雄、津本浩平
    • Organizer
      日本化学会第94春季年会
    • Place of Presentation
      名古屋大学東山キャンパス( 愛知県名古屋市)
    • Year and Date
      2014-03-27 – 2014-03-30
    • Data Source
      KAKENHI-PROJECT-25249115

  • [Presentation] プロテオグリカンOsteomodulinの物理化学的解析
    • Author(s)
      田島卓実、中木戸誠、長門石曉、大沼信一、津本浩平
    • Organizer
      日本化学会第94春季年会
    • Place of Presentation
      名古屋大学東山キャンパス( 愛知県名古屋市)
    • Year and Date
      2014-03-27 – 2014-03-30
    • Data Source
      KAKENHI-PROJECT-25249115

  • [Presentation] 機能制御を目指した疾患関連蛋白質Mint3の物性解析
    • Author(s)
      中山佳昭、田代晋也、長門石曉、坂本毅治、清木元治、津本浩平
    • Organizer
      第14回日本蛋白質科学会
    • Place of Presentation
      ワークピア横浜(神奈川県横浜市)
    • Year and Date
      2014-06-25 – 2014-06-27
    • Data Source
      KAKENHI-PROJECT-25249115

  • [Presentation] 黄色ブドウ球菌由来の莢膜合成酵素CapFに結合する低分子化合物の解析
    • Author(s)
      長門石曉、中納 広一郎、宮房 孝光、Caaveiro Jose、津本 浩平