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Kataoka Kazunori  片岡 一則

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KATAOKA Kazunori  片岡 一則

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Researcher Number 00130245
Other IDs
Affiliation (Current) 2023: 公益財団法人川崎市産業振興財団(ナノ医療イノベーションセンター), ナノ医療イノベーションセンター, センター長
Affiliation (based on the past Project Information) *help 2017 – 2023: 公益財団法人川崎市産業振興財団(ナノ医療イノベーションセンター), ナノ医療イノベーションセンター, センター長
2017: 公益財団法人川崎市産業振興財団(ナノ医療イノベーションセンター), その他部局等, その他
2017: 公益財団法人川崎市産業振興財団, ナノ医療イノベーションセンター, センター長
2016: 公益財団法人川崎市産業振興財団(ナノ医療イノベーションセンター), 川崎市産業振興財団, センター長
2016: 公益財団法人川崎市産業振興財団(ナノ医療イノベーションセンター), センター長 … More
2016: 公益財団法人川崎市産業振興財団, ナノ医療イノベーションセンター, 主幹研究員
2016: 東京大学, 工学研究科, 教授
2016: 東京大学, 疾患生命工学センター, 教授
2013 – 2015: 東京大学, 大学院工学系研究科, 教授
2012 – 2015: 東京大学, 工学(系)研究科(研究院), 教授
2014: 東京大学, 大学院工学研究科, 教授
2011 – 2014: 東京大学, 工学系研究科, 教授
2012: 東京大学, 工学系研究院, 教授
1998 – 2011: 東京大学, 大学院・工学系研究科, 教授
2007: The University of Tokyo, Faculty of engineering, Professor
2006 – 2007: 東京大学, 工学系研究科, 教授
2005 – 2006: 東京大学, 医学部附属病院, 教授
2005 – 2006: 東京大学, 大学院工学系研究科, 教授
2005: The University of Tokyo, Graduate School of Medicine, Professor, 大学院・医学系研究科, 教授
2005: 東京大学, 大学院医学系研究科, 教授
2003: University of Tokyo, Materials Science, Professor, 大学院工学系研究科, 教授
2003: 東京大学, 工学系研究科, 教授
2002: 東京大学, 大学院・工学研究科, 教授
2002: The University of Tokyo, Graduate School of Engineering, Professor, 大学院・工学系研究科, 教授
2001: The University of Tokyo, Materials Science, Professor, 工学部, 教授
1998 – 2000: 東京大学, 大学院・工学系, 教授
1994 – 1997: Science University of Tokyo, Department of Materials Science and Technology, Professor, 基礎工学部, 教授
1989 – 1993: Science University of Tokyo, Department of Materials Science, Associate Professor, 基礎工学部, 助教授
1988: 東京女子医科大学, 医用工学研究施設, 助教授
1987: Institute of Biomedical Engineering, Tokyo Women's Medical College, 医用工学研究施設, 講師
1986: 東京女子医科大, 学・医用工学研究施設, 講師
1986: 東京女子医科大学, 医学部, 講師 Less
Review Section/Research Field
Principal Investigator
Biomedical engineering/Biological material science / Medium-sized Section 90:Biomedical engineering and related fields / 広領域 / Science and Engineering / Polymer chemistry / Biomedical engineering/Biological material science / Medium-sized Section 50:Oncology and related fields / 高分子合成 / Chemistry / Biological Sciences / 高分子構造・物性(含繊維) … More
Except Principal Investigator
… More Biomedical engineering/Biological material science / Cerebral neurosurgery / Biomedical engineering/Biomaterial science and engineering / Surgical dentistry / Ophthalmology / Basic Section 90120:Biomaterials-related / Urology / Plastic surgery / General surgery / Digestive surgery / Nuclear engineering / Science and Engineering / Orthopaedic surgery / Basic Section 90110:Biomedical engineering-related / Biomedical engineering/Biomaterial science and engineering / Cardiovascular medicine / 広領域 / Digestive surgery / Orthopaedic surgery / Metabolomics / Circulatory organs internal medicine / Material processing/treatments / 高分子構造・物性(含繊維) / Biomedical engineering/Biological material science / Biomedical engineering/Biological material science / Physical pharmacy Less
Keywords
Principal Investigator
高分子ミセル / ブロック共重合体 / ポリエチレングリコール / ドラッグデリバリー / DNA / ポリアミノ酸 / 遺伝子治療 / グルコース / がん免疫療法 / Block copolymer … More / フェニルボロン酸 / polymeric micelle / アドリアマイシン / がん治療 / siRNA / ポリアスパラギン酸 / ポリ乳酸 / ポリイオンコンプレックス / 血液脳腫瘍関門 / 免疫チェックポイント阻害剤 / ドラッグデリバリーシステム / 抗体 / Poly(ethylene glycol) / Insulin / インシュリン / Polymer micelle / 遺伝子デリバリー / lymphocyte / リンパ球 / block copolymer / poly (aspartic acid) / poly (ethylene glycol) / 制ガン剤 / がん標的治療 / 化学療法 / ナノテクノロジー / がん化学療法 / ポリイオンコンプレックスミセル / ルシフェラーゼアッセイ / ガラクトース / 抗ガン剤 / ポリリシン / 遺伝子ベクター / 走化性制御 / mRNA療法 / 細胞傷害性リンパ球 / 膠芽腫 / mRNA / リガンド分子 / 還元環境応答性 / タンパク質デリバリー / 脳腫瘍 / Adriamycin / Poly(amino acid) / Drug delivery system / Antibody / Missile drug / ハイブリッド抗体 / 高分子制ガン剤 / ポリエチレングリコール-ポリアミノ酸ブロック共重合体 / ポリエチレングリコ-ル / ドラッグデリバリ-システム / ミサイルドラッグ / nanotechnology / cancer targeted therapy / environment sensitivity / chemotherapeutic agents / cancer chemotherapy / polymeric micelles / drug delivery / 放出制御 / 細胞内環境応答性 / 抗がん剤 / pH応答性 / DDS / 制がん剤 / がん / 環境応答性 / polyethylene glycol / Biocompartibility / nanocapsul / gene delivery / 生体適合性 / ナノカプセル / Protein adsorption / Surface coating / Biocompatibility / Core-shell structure / Polymeric micelle / Polylactide / コアーシェル型超微粒子 / タンパク質吸着 / 表面コーティング / 生体適合表面 / コア-シェル型超微粒子 / Gene therapy / Drug delivery device / Pancreatic beta cell / Nano-associate / Chemical valva / Materials sysytem / Molecular Synchronization / ケミカルバルブ / 薬物送達デバイス / 膵ベータ細胞 / ナノ会合体 / ケミカルバイブ / 材料システム / 分子シンクロナイゼーション / Intelligent gel / Diabetes / Drug delivery / Poly (N-isopropylacrylamide) / Phenylboronic acid / Polymeric gel / Glucose / インテリジェントゲル / 糖尿病 / ポリ(N-イソプロピルアクリルアミド) / 高分子ゲル / Gene delivery / Luciferese assay / Polyion complex / Gene vector / ヌクレアーゼ / pyrene / polylysine / dynamic ligh scattering / poly (amino acid) / peptide / ポリマーミセル / ヒドロ桂皮酸 / フェニルアラニン / α-アミノ酸N-カルボン酸無水物 / ピレン / 動的光散乱 / ペプチド製剤 / mitogenic activity / artificial lectin / fluoro-phenylboronic acid / maleic anhydrode / N-vinylpyrrolidone / N,N-dimethylacrylamide / phenylboronic acid / マイトジェン活性化 / 無水マレイン酸 / マイトジジェン活性 / 人工レクチン / フルオロ化フェニルボロン酸 / 無水マイレン酸 / N-ビニルピロリドン / N,N-ジメチルアクリルアミド / multi-phase polymeric materials / electrostatic interaction / graft copolymer / polyamine / field flow fractionation / chromatography / cell separation / ミクロドメイン構造 / 高分子吸着体 / 多相系高分子材料 / 静電相互作用 / グラフト共重合体 / ポリアミン / 作用場流動分画法 / クロマトグラフィー / 細胞分離 / solid tumor / pharmacokinetics / heterobifunctional oligomer / adriamycin / 薬物ターゲティング / ヘテロニ官能性オリゴマー / 固型ガン / 体内動態 / ヘテロ二官能性オリゴマー / グルコーストランスポ-ター / 脳―血液関門 / 脳一血液関門 / グルコーストランスポーター / アルツハイマー病 / 脳-血液関門 / 抗体医薬 / プラスミドDNA / メッセンジャーRNA / アンチセンス核酸 / 血液脳関門(BBB) / 薬物送達システム / 自己組織化 / 高分子構造・物性 / ナノバイオ材料 / 生体関連高分子 / MRI / リポソーム / 中空ナノ粒子 / 機能ポ性リマー / 機能性ポリマー / ナノキャリア / PDT効果 / 光線力学療法 / デンドリマー型光増感剤 / 界面密度 / コアーシェル構造 / プロック共重合体 / ポリ-L-リシン / ホスト-ゲスト / ホモポリマー / ナノスフィア / ウイルス / 人工ウイルス … More
Except Principal Investigator
高分子ミセル / ナノ材料 / ブロック共重合体 / DDS / 遺伝子治療 / ナノバイオ / ナノミセル / ドラッグデリバリーシステム / RGD / bFGF / Reverse transfection / 生体材料 / 癌 / ドラッグ・デリバリー / 悪性脳腫瘍 / DNA / 化学療法 / block copolymer / 脳神経疾患 / siRNA / PEG / 表面処理 / ヘテロポリエチレングリコール / 高分子 / 遺伝子導入 / タンパク質吸着 / 細胞分離 / 細胞増殖 / 膀胱癌 / マイクロRNA / 抗体 / VEGFR2 / ナノキャリア / 循環器・高血圧 / X-band / biomedical material / nano material / Drug Delivery / Central Nervous System / Cancer / ドラッグ・デリバリー・システム / PEG-DET / Recipient bed / In vivo electroporation / Axial skin flap / 高分子ナノミセル構造体 / Polymer nano-micellsb / Acidic gelatin hydrogel / 高分子ミセル型ナノ・パーティクル / 血管新生療法 / 塩基性線維芽細胞増殖因子 / Artery wall binding peptide / RGDペプチド / 酸性ゼラチンハイドロゲル / MRI / ISFET / BLOCK COPOLYMER MICELLE / POLY(ETHYLENE GLYCOL) / ぬれ / 血液適合性 / ポリマーブラシ / ブロックコポリマー / ミクロドメイン構造 / ナノDDS / 脳腫瘍学 / miRNA / YB-1 / トランスレーショナル・リサーチ / マイクロアレイ / 移植・再生医療 / ナノテクノロジー / 血管新生 / ドラッグデリバリー / タンパク吸着 / 生体適合性 / ポリ乳酸 / PEGブラシ表面 / ミセル / 遺伝子ベクター / 生理活性物質 / 細胞多次元配列制御 / 人工組織体 / アフィニティラテックス / バイオ複合材料 / CRISPR/Cas9 / ゲノム編集 / RNA医薬 / mRNA / 免疫チェックポイント阻害剤 / がん免疫療法 / がん / 酵素-プロドラッグ療法 / 活性酸素種 / 酵素プロドラッグ療法 / 高分子ベシクル / がん治療 / 白金制がん剤 / ビタミンC / 酸化還元反応 / 金属錯体 / がんの標的治療 / 原因治療 / 遺伝学 / 心筋症 / 循環器 / microRNA / 癌抑制型マイクロRNA / 難治性疾患 / タンパク質 / 脳 / 薬剤送達システム / Ionic interaction / Microdomain structure / Polymamine / Graft copolymer / Polymeric adsorbent / Lymphocyte subpopulation / Cell separation / マクロマー / イオン性相互作用 / ポリアミン / グラフト共重合体 / 高分子吸着体 / リンパ球亜集団 / Semi-premeable Polymer Membrane / Xenograft Implantation / Isograft Implantation / Islet Transplantation / Monolayer Culture / Bio-artificial Endocrine Pancreas / Deabet / 浮遊培養 / 合成高分子膜 / Diffusion Chamber / ハイブリッド型人工膵臓 / 糖尿病治療 / diffusion Chamber / 反透過性高分子膜 / 異種移植 / 同系移植 / 膵島移植 / 単層培養 / バイオ型人工膵臓 / 糖尿病 / genome microarray chips / immunotherapy / choroidal neovascularization / polyion complex micelle / photodynamic therapy / age-related macular degeneration / 免疫学 / サルゲノムマイクロアレイ / 特異的免疫賦活化療法 / 脈絡膜新生血管 / 光線力学療法 / 加齢黄斑変性 / platelet-activating factor / osteoclast / bone destruction / lipid mediator / 骨破壊病変遺伝子治療 / 非病原性ベクター / 血小板活性化因子 / 破骨細胞 / 骨破壊性病変 / 脂質メディエータ / polyplex micelle / nanotechnology / bone and joint disease / nanocarrier / delivery system / 骨軟骨疾患 / デリバリーシステム / Circulation, Hypertension / Surgery / Nano-material / 外科 / Dual-energy X-ray CT / Inverse Compton scattering X-ray source / Electron linac / 生物物理 / 廃棄物処理 / 加速器 / 放射線,X線,粒子線 / 2色X線CT / コンプトン散乱X線源 / 電子線形加速器 / Vascular tissue / Gene delivery / Bone regeneration / collagen gel / Reverse transfect / 血管組織 / 再生骨 / コラーゲンゲル / Polymerization / Atherosclerosis lesion selective / Polymer vector / in vivo gene transfer / Intra tracheal gene transfer / Nano-particle / Gene therapy / THP-1細胞 / 血管内皮細胞 / 血中安定性 / SS結合 / 遺伝子導入ベクター / 重合度 / 動脈硬化巣選択的 / ポリマーベクター / in vivo遺伝子導入 / 気管内投与 / 高分子ナノ微粒子 / Polymer micelle / Micropheres / Electroporation / Skin flap / Recipient b / マイクロスフィアー / Therapeutic angiogenesis / Rabbit carotid artery / Intimal Hyperplasia / TRAF6 / 治療的血管新生 / 高分子ミセル型ナノパーティクル / コーティング / 高分子ミセル型ナノパーティク / 治療的血管新生療法 / ウサギ頚動脈 / 内膜肥厚 / 高分子ミセル型ナノパーテ / confocal microscopy / fluorescence resonance energy transfer / PIC micelle / polymer / gene delivery / レーザー共焦点顕微鏡 / 蛍光エネルギー移動 / contrast agent / iron / magnetic resonance imaging / unstable plaque / atherosclerosis / arteriosclerosis / ガドリニウム / 高分子共重合体 / 造影剤 / 鉄 / 磁気共鳴画像 / 不安定プラーク / 動脈硬化 / azomethine bond / poly(ethylene glycol) / targeting / adriamycin / hydrazone / block copolyme / pH responsive / polymeric micelle / 制ガン剤 / アゾメチン結合 / ポリエチレングリコール / 標的指向性 / アドリアマイシン / ヒドラジド基 / pH応答性 / Salt Bridge / Lymphocyte separation / Electroosmosis flow pump / Health marker / Painless Needle / Bio chip / Healthcare device / 生体適合化 / マイクロキャピラリ / 塩橋 / リンパ球分離 / 電気浸透流ポンプ / 健康マーカ / 無痛針 / バイオチップ / ヘルスケアデバイス / POLY-L-LYSINE / LIVER / CATIONIC POLYMER / HEP G2 CELL / PIC MICELLES / BLOCK COPOLYMER / NON-VIRAL VECTOR / GENE THERAPY / DNAコンプレックス / ポリマー / ポリLリジン / 肝臓 / カチオニックポリマー / HepG2細胞 / PICミセル / 共重合体 / non-viralベクター / PEGYLATED PROTEIN / HETERO-PEG / MEDIATED ENDOCYTOSIS / ACTIVE TARGETING DDS / ポリエチレングリコーリル / 臨界会合濃度 / ビオチン / アクティブターゲティング / タンパク修飾 / ヘテロテレケリックス / 高分子ミセルキャリア / ガラクトースレセプタ / PEG化タンパク / 薬物ターゲッティング / NON-FOULING SURFACE / BIOCOMPATIBLE SURFACE / HIGH DENSITY TETHERED CHAIN / SURFACE MODIFICATION AGENTS / POLY(HEMA) / ポリヒドロキシエチルメタクリレート / セミテレケリックス / アニオン重合 / ポリ(メタクリル酸2-ヒドロキシエチル) / マイクロチップ / 反応性粒子 / ポリマーミセル / Information system / Electronics device / Nanobiotechnology / Materials System / Molecular Synchronization / 材料設計 / デバイス構築 / バイオリズム / 材料システム設計 / 運動リズム / 情報変換 / 物質輸送 / エネルギー効率化 / マイクロ・ナノデバイス / 電子デバイス / 情報システム / 電子デバイス機器 / 材料システム / 分子シンクロナイゼーション / SPINODAL SEPARATION / ACTUATOR / STIMULI-SENSITIVE GEL / RUBBER ELASTICITY TRANSITION / HYDROGEL / POLY(SILOXYETHYLENE GLYCOL) / POLY(SILAMINE) / 弾性率 / テレケリックス / 刺激答性ゲル / 相転移 / ボリサイラミン / スピノーダル分解 / アクチュエータ / 刺激応答性ゲル / ゴム弾性転移 / ハイドロゲル / ポリサイロキシエチレングリコール / ポリサイラミン / Gas permselective membrane / polymer brush / Silicon-containing polymers / poly (2-hydroxyethyl methacrylate) / Antithrombogenicity / Artificial lung / 膨潤度 / 多相系表面 / ガス透過 / 含ケイ素ポリマー / ガス透過膜 / ガンケイ素ポリマー / ポリヒドロキシメタクリレート / 抗血栓性 / 人工肺 / 細胞吸着クロマトグラフィー / ポリ(メタクリル酸2-ヒドロキシエチル)-ポリアミングラフト共重合体 / リンパ球亜集団分離 / 細胞特異的材料 / 脳神経腫瘍 / 脳腫瘍 / 癌微小環境 / デコイ / 骨移植片 / 骨再生 / 骨再生用移植片 / Rac-1 / ROS / TNF-α遺伝子 / TNF-α / GM-CSF / CD40L / TNF一α / 外傷治療 / 骨格筋 / 外傷 / バイオテクノロジー / 遺伝子 / 発生・分化 / 骨形成性シグナル / 人工ウイルス / 再生医療 / 遺伝子デリバリーシステム / デンタルインプラント / 人材育成 / 生体シミュレーター / イメージガイド照射システム / 放射線治療 / 医学物理 / ナノテクノロシー / 光力学療法 / 角膜 / 脳血管内皮細胞 / ニューロン / 血液-脳関門 / アルツハイマー病 / 血液脳関門 / 集積回路 / シラノールポリマーブロック / シランカップリング剤 / 透過制御 / ハイドロゲルミセル / 反応性ナノ粒子 / ウイルス / 安定性 / 分子機構 / 体内動態 / レセプター / 医薬品開発 / 薬物治療 / 分子組織 / バイオセンサ / バイオ素子 / 分子系超構造 / 光駆動リン酸化システム / 高分子ヘテロ構造体 / 自己組織化能 / 融合タンパク質 / カルモジュリン / リポソーム / タリン / H^+-ATP合成酵素 / アパタイト / リゾチーム / ナノ会合体 / 脂質修飾抗体 / 自己組織化 / ヒドロゲルミクロスフェア / 人工レセプター / ポリアミノ酸ビ-ズ / 細胞組織化 / ニュ-ラル・ネットワ-ク / ハイブリッドミクロスフェア / 生物応答調節剤 / 人工レクチン / 固定化タンパク質 / 人工レセプタ- Less
  • Research Projects

    (78 results)
  • Research Products

    (1,007 results)
  • Co-Researchers

    (138 People)
  •  Cancer immunotherapy with mRNA-loaded polymeric micelles for in situ creation of tumor-infiltrating killer cellsPrincipal Investigator

    • Principal Investigator
      片岡 一則
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 90:Biomedical engineering and related fields
    • Research Institution
      Kawasaki Institute of Industrial Promotion Innovation Center of NanoMedicine
  •  Development of polymeric micellar nanocarrier for messenger RNA deliveryHost Researcher

    • Host Researcher
      片岡 一則
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Review Section
      Basic Section 90120:Biomaterials-related
    • Research Institution
      Kawasaki Institute of Industrial Promotion Innovation Center of NanoMedicine
  •  In vivo genome editing using hepatocyte-targeted RNA delivery systemHost Researcher

    • Host Researcher
      片岡 一則
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Review Section
      Basic Section 90110:Biomedical engineering-related
    • Research Institution
      Kawasaki Institute of Industrial Promotion Innovation Center of NanoMedicine
  •  Development of polymeric micelles for photothermal/suicide gene therapy combined with immune checkpoint blockageHost Researcher

    • Host Researcher
      片岡 一則
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Review Section
      Basic Section 90120:Biomaterials-related
    • Research Institution
      Kawasaki Institute of Industrial Promotion Innovation Center of NanoMedicine
  •  Development of brain tumor-penetrant protein delivery system realizing immunotherapy of malignant brain tumorPrincipal Investigator

    • Principal Investigator
      Kataoka Kazunori
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 90:Biomedical engineering and related fields
    • Research Institution
      Kawasaki Institute of Industrial Promotion Innovation Center of NanoMedicine
  •  Pioneering glioblastoma therapy by in situ mRNA-based amplification of immune checkpoint inhibitorsPrincipal Investigator

    • Principal Investigator
      Kataoka Kazunori
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Challenging Research (Pioneering)
    • Review Section
      Medium-sized Section 50:Oncology and related fields
    • Research Institution
      Kawasaki Institute of Industrial Promotion Innovation Center of NanoMedicine
  •  ミクロ流体デバイスを用いた薬物内包多層微粒子の作成とがん標的治療への展開Host Researcher

    • Host Researcher
      片岡 一則
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Research Field
      Biomedical engineering/Biomaterial science and engineering
    • Research Institution
      Kawasaki Institute of Industrial Promotion Innovation Center of NanoMedicine
  •  腫瘍内で薬剤を長期間にわたって生成するナノリアクタシステムの構築Host Researcher

    • Host Researcher
      片岡 一則
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Research Field
      Biomedical engineering/Biomaterial science and engineering
    • Research Institution
      Kawasaki Institute of Industrial Promotion Innovation Center of NanoMedicine
  •  Development of multi-functional protein based nanoparticles for anti-tumor drug deliveryHost Researcher

    • Host Researcher
      片岡 一則
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Research Field
      Biomedical engineering/Biomaterial science and engineering
    • Research Institution
      Kawasaki Institute of Industrial Promotion Innovation Center of NanoMedicine
  •  Development of super-selective cancer therapy by utilizing vitamin C-activatable oxidized polymeric micelles

    • Principal Investigator
      Mochida Yuki
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Biomedical engineering/Biomaterial science and engineering
    • Research Institution
      Kawasaki Institute of Industrial Promotion Innovation Center of NanoMedicine
  •  Development of novel nucleic acid treatment through nano-micelles delivering tumor suppressive microRNA in bladder cancer

    • Principal Investigator
      ENOKIDA Hideki
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Urology
    • Research Institution
      Kagoshima University
  •  Study for elucidating tumor suppressive microRNA that has anti proliferation and prevent metastasis by using metastasis model mouse in bladder cancer

    • Principal Investigator
      ITESAKO Toshihiko
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Kagoshima University
  •  Development of a new therapeutic strategy for cardiomyopathy by administration of mRNA

    • Principal Investigator
      Onoue Kenji
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cardiovascular medicine
    • Research Institution
      Nara Medical University
  •  脳内にsiRNAを送達する高分子ミセルの創製とアルツハイマー病の標的治療への展開Host Researcher

    • Host Researcher
      片岡 一則
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      The University of Tokyo
  •  Development of Polymeric Micelles for Brain-Targeted Delivery of Nucleic Acid Drugs to Treat Intractable Neurological DiseasesPrincipal Investigator

    • Principal Investigator
      KATAOKA Kazunori
    • Project Period (FY)
      2013 – 2017
    • Research Category
      Grant-in-Aid for Specially Promoted Research
    • Review Section
      Science and Engineering
      Chemistry
    • Research Institution
      Kawasaki Institute of Industrial Promotion Innovation Center of NanoMedicine
      The University of Tokyo
  •  Development of YB-1-silencing miRNA/ decoy gene therapy against intractable solid tumor to regulate malignant microcircumstances

    • Principal Investigator
      NAKANO Kenji
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
  •  Development of efficient drug and gene delivery system for malignant brain tumors using polymeric nanomicelles.

    • Principal Investigator
      INO Yasushi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      The University of Tokyo
  •  siRNAをビルディングブロックとする超分子構造体の創出と機能開発Principal Investigator

    • Principal Investigator
      片岡 一則
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Polymer chemistry
    • Research Institution
      The University of Tokyo
  •  Examination of hybrid bone grafts using nano DDS and artificial bones

    • Principal Investigator
      MORI Yoshiyuki
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Surgical dentistry
    • Research Institution
      The University of Tokyo
  •  A novel approach to treat severe trauma using gene introduction by nanomicelle into skeletal muscle

    • Principal Investigator
      ITAKA Keiji
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      The University of Tokyo
  •  Multidiciplinary TNF・a based gene therapy using polyplex micelle

    • Principal Investigator
      NAKA Nokenjl
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
  •  Development of selective and efficient drug delivery system for malignant brain tumors using polymeric nanomicelles.

    • Principal Investigator
      INO Yasushi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      The University of Tokyo
  •  生体内環境耐性と応答性を兼備したリピド被覆型高分子ミセルドラッグPrincipal Investigator

    • Principal Investigator
      片岡 一則
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Polymer chemistry
    • Research Institution
      The University of Tokyo
  •  Development of multifunctional polymeric micelles for systemic siRNA deliveryPrincipal Investigator

    • Principal Investigator
      KATAOKA Kazunori
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      The University of Tokyo
  •  Novel approach for management of age-related macular degeneration using nanotechnology

    • Principal Investigator
      TAMAKI Yasuhiro
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Ophthalmology
    • Research Institution
      The University of Tokyo
  •  研究開発的医学物理創成と人材育成

    • Principal Investigator
      UESAKA Mitsuru
    • Project Period (FY)
      2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Nuclear engineering
    • Research Institution
      The University of Tokyo
  •  ナノテクノロジーを利用した骨誘導性デンタルインプラントシステムの開発

    • Principal Investigator
      高木 源一郎
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Surgical dentistry
    • Research Institution
      The University of Tokyo
  •  New Treatment for Age-related Macular Degeneration Antiangiogenic Thereapy using Nanotechnology and Retianl Regenerative Therapy

    • Principal Investigator
      TAMAKI Yasuhiro
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Ophthalmology
    • Research Institution
      The University of Tokyo
  •  Novel Approach for Brain Tumor Treatment using Nano-micelle Drug Delivery System

    • Principal Investigator
      INO Yasushi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      The University of Tokyo
  •  Polymeric micelle nanocarrier for drug and gene deliveryPrincipal Investigator

    • Principal Investigator
      KATAOKA Kazunori
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  角膜血管新生に対する高分子ナノミセルを用いたドラッグデリバリーシステムの開発

    • Principal Investigator
      杉崎 顕史
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Ophthalmology
    • Research Institution
      The University of Tokyo
  •  Development of functional polymeirc micelles responding to intracellular microenvironments for cancer chemotherapyPrincipal Investigator

    • Principal Investigator
      KATAOKA Kazunori
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      The University of Tokyo
  •  Development of application of compact tunable monochromatic X-ray source

    • Principal Investigator
      UESAKA Mitsuru
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Nuclear engineering
    • Research Institution
      THE UNIVERSITY OF TOKYO
  •  Gene delivery using polyion complex micelle for the treatment of aortic aneurysm

    • Principal Investigator
      MIYATA Tetsuro
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      The University of Tokyo
  •  Development of multi-functional nanocarrier of siDNA and application for bone and joint diseases

    • Principal Investigator
      ITAKA Keiji
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  Gene therapy targeting lipid mediators for prevention of bone destruction

    • Principal Investigator
      HIKIJI Hisako
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Surgical dentistry
    • Research Institution
      The University of Tokyo
  •  Novel tissue regeneration using polymer nano-micelle gene delivery system

    • Principal Investigator
      TAKATO Tsuyoshi
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Plastic surgery
    • Research Institution
      The University of Tokyo
  •  Nano-micelle Drug Delivery System for the Treatment of Brain Tumors

    • Principal Investigator
      INO Yasushi
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      The University of Tokyo
  •  New support system of vascular surgery using novel bio-materials

    • Principal Investigator
      KOYAMA Hiroyuki
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      The University of Tokyo
  •  Non-invasive soft tissue reconstruction using therapeutic angiogenesis.

    • Principal Investigator
      EGUCHI Tomoaki
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Plastic surgery
    • Research Institution
      The University of Tokyo
  •  Development of the vectors for atherosclerosis lesion specific gene delivery using polyion compex micelles

    • Principal Investigator
      SHIBA Mariko
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      National Cardiovascular Center Research Institute
  •  特異的光線力学療法のためのデンドリマー型光増感剤内包高分子ミセルの創製Principal Investigator

    • Principal Investigator
      片岡 一則
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      The University of Tokyo
  •  Creation of intelligent polymeric micelle nanocapsuls for gene deliveryPrincipal Investigator

    • Principal Investigator
      KATAOKA Kazunori
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      The University of Tokyo
  •  Development of novel contrast agents combined by block coplolymers to detect unstable atherosclerotic plaques

    • Principal Investigator
      KANEKO Eiji
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Tokyo Medical and Dental University
  •  Development of PIG micelle vector system for gene delivery

    • Principal Investigator
      HOSHI Kazuto
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  反応性ポリマーブラシ構造に基づく高機能マイクロチップインターフェースの構築

    • Principal Investigator
      長崎 幸夫
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Science and Engineering
    • Research Institution
      Tokyo University of Science
  •  ブロック共重合体ミセル形成時の鎖長識別現象に基づく新規ホスト-ゲスト系の構築Principal Investigator

    • Principal Investigator
      片岡 一則
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      高分子構造・物性(含繊維)
    • Research Institution
      The University of Tokyo
  •  人工ウイルス(高分子ミセル型ベクター)を用いた細胞内遺伝子導入法の確立

    • Principal Investigator
      KAWAGUCHI Hiroshi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Orthopaedic surgery
    • Research Institution
      The University of Tokyo
  •  高分子ミセルゲルの構築と薬物透過コントロール材料としての評価

    • Principal Investigator
      長崎 幸夫
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      Tokyo University of Science
  •  Creation of health care device employing micro analysis chip of trace amount of blood

    • Principal Investigator
      HORIIKE Yasuhiro
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Material processing/treatments
    • Research Institution
      The University of Tokyo
  •  Development of novel pH-responsive block copolymer micelles for drug targeting

    • Principal Investigator
      HARADA Atsushi
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      The University of Tokyo
  •  Creation ofPolumeric Drugs and Drug Carriers Possessing Pilot Molecules on the Surface and Their Application for Targeting Therapy

    • Principal Investigator
      YUKIO Nagasaki
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      SCIENCE UNIVERSITY OF TOKYO
  •  Biomedical approach of new materials with well-organized interfacesPrincipal Investigator

    • Principal Investigator
      KATAOKA Kazunori
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      The University of Tokyo
  •  DEVELOPMENT OF THE METHOD OF GENE DELIVERY USING BLOCK COPOLYMER FOR THE TREATMENT OF CARDIOVASCULAR DISEASES

    • Principal Investigator
      SEHIBA Mariko
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Institution
      NATIONAL CARDIOVASCULAR CENTER RESEARCH INSTITUTE
  •  標的認識性糖鎖を配置した高分子ミセルの構築とその薬物ターゲティングへの展開Principal Investigator

    • Principal Investigator
      片岡 一則
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokyo
  •  パイロット素子を表層に提示したウイルス様ナノスフィアによる遺伝子ターゲティングPrincipal Investigator

    • Principal Investigator
      片岡 一則
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokyo
  •  Molecular Synchronization for Design of New Materials System

    • Principal Investigator
      AKAIKE Toshihiro
    • Project Period (FY)
      1998 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Science and Engineering
    • Research Institution
      Tokyo Institute of Technology
  •  Creation of High Performance Biocompatible Surface by Surface modification agent which Constructs High Density Tethered Chains

    • Principal Investigator
      NAGASAKI Yukio
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      SCIENCE UNIVERSITY OF TOKYO
  •  Development of self-regulated insulin delivery system based on novel glucose-responsive gelPrincipal Investigator

    • Principal Investigator
      KATAOKA Kazunori
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      広領域
    • Research Institution
      The University of Tokyo
  •  Design of chemical valve system based on the concept of molecular-specific synchronizationPrincipal Investigator

    • Principal Investigator
      KATAOKA Kazunori
    • Project Period (FY)
      1998 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Science and Engineering
    • Research Institution
      The University of Tokyo
  •  標的認識性糖鎖を配置した高分子ミセルの構築とその薬物ターゲッティングへの展開Principal Investigator

    • Principal Investigator
      片岡 一則
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo University of Science
  •  MOLECULAR DESIGN FOR NOVEL STIMULI-SENSITIVE GELS

    • Principal Investigator
      KATO Masao
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      高分子構造・物性(含繊維)
    • Research Institution
      Tokyo University of Science
  •  Preparation and evaluation of block copolymer micelle for novel gene vectorPrincipal Investigator

    • Principal Investigator
      KATAOAKA Kazunori
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      The University of Tokyo
      Tokyo University of Science
  •  ドラッグデリバリーの空間的・時間的制御

    • Principal Investigator
      橋田 充
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Physical pharmacy
    • Research Institution
      Kyoto University
  •  生体分子素構造の人工的組織構造化による新機能発現

    • Principal Investigator
      相澤 益男
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo Institute of Technology
  •  Molecular design of polymer with lymphocyte-activating abilityPrincipal Investigator

    • Principal Investigator
      KATAOKA Kazunori
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      Science University of Tokyo
  •  Design and characterization of polymeric micelles with entrapped peptidesPrincipal Investigator

    • Principal Investigator
      KATAOKA Kazunori
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      Science University of Tokyo
  •  Development of novel membrane type artificial lung having controlled surface morphology

    • Principal Investigator
      NAGASAKI Yukio
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      Science University of Tokyo
  •  新しい遺伝子ベクターの設計:DNAを内包するcore-shell型ブロック共重合体ミセルの構築とがん遺伝子治療への展開Principal Investigator

    • Principal Investigator
      片岡 一則
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo University of Science
  •  Drug targeting by block copolymer micelle having targeting moietyPrincipal Investigator

    • Principal Investigator
      KATAOKA Kazunoei
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      広領域
    • Research Institution
      Science University of Tokyo
  •  Development of contimous cell separation system using polymeric adsorbent with surface micro-structuresPrincipal Investigator

    • Principal Investigator
      KATAOKA Kazunori
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      Science University of Tokyo
  •  生体特異的界面応答機能を有する材料の合成と機能制御

    • Principal Investigator
      今西 幸男
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  生体特異的界面応答機能を有する材料の合成と機能制御

    • Principal Investigator
      今西 幸男
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  生体特異的界面応答機能を有する材料の合成と機能制御

    • Principal Investigator
      今西 幸男
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  Synthesis and Evaluation of Polymer-Antibody Hybrid with Pharmacologically Active DomainsPrincipal Investigator

    • Principal Investigator
      KATAOKA Kazunori
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      高分子合成
    • Research Institution
      Science University of Tokyo
      Tokyo Women's Medical University
  •  細胞特異的分離・認識機能を有する高分子材料

    • Principal Investigator
      SAKURAI Yasuhisa
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo Women's Medical University
  •  Separation of lymphocyte subpopulations by novel polymeric adsorbent with controlled micro-structure

    • Principal Investigator
      TSURUTA Teiji
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for Developmental Scientific Research
    • Research Field
      広領域
    • Research Institution
      Science University of Tokyo
  •  Studies on Diffusion Chamber for Bio-artificaial Endocrine Pancreas

    • Principal Investigator
      SAKURAI Yasuhisa
    • Project Period (FY)
      1985 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Tokyo Women's Medical College

All 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 Other

All Journal Article Presentation Book Patent

  • [Book] Chap. 18疾患部位で薬を『つくる』ナノマシンの構築/Development of nano-machines that produce drugs at the disease site CSJ CurrentReview 26 分子マシンの科学 分子の動きとその機能を見る/Science of Molecular Machine2017

    • Author(s)
      安楽泰孝、片岡一則
    • Pages
      171-177
    • Total Pages
      200
    • Publisher
      日本化学会
    • Data Source
      KAKENHI-PROJECT-25000006
  • [Book] SiRNA delivery methods (Preparation of polyion complex micelles using block copolymers for SiRNA delivery)2016

    • Author(s)
      H. -J. Kim, M. Zheng, K. Miyata, K. Kataoka
    • Total Pages
      313
    • Publisher
      Springer (New York, USA)
    • Description
      【発行確定】
    • Data Source
      KAKENHI-PROJECT-25000006
  • [Book] 高分子ナノミセルを用いた生体へのin vivo mRNAデリバリー(トランスレーショナルリサーチを支援する遺伝子医学MOOK30号)2016

    • Author(s)
      内田智士、位高啓史、片岡一則
    • Pages
      119-124
    • Total Pages
      300
    • Publisher
      株式会社メディカルドゥ
    • Data Source
      KAKENHI-PROJECT-25000006
  • [Book] 高分子集合体に基づく核酸デリバリーシステム(核酸医薬の創製と応用展開)2016

    • Author(s)
      宮田完二郎、片岡一則
    • Pages
      175-184
    • Total Pages
      278
    • Publisher
      シーエムシー出版
    • Data Source
      KAKENHI-PROJECT-25000006
  • [Book] Nanoparticles in the lung : environmental exposure and drug delivery(Drug and gene delivery in the lungs)2015

    • Author(s)
      S. Uchida, K. Itaka, K. Kataoka
    • Total Pages
      403
    • Publisher
      CRC press, Taylor & Francis Group(Florida, USA)
    • Description
      【発行確定】
    • Data Source
      KAKENHI-PROJECT-25000006
  • [Book] Nonviral Vectors for Gene Therapy : Lipid-and Polymer-based Gene Transfer(Bioresponsive polymer-based nucleic acid carriers)2014

    • Author(s)
      H. Takemoto, K. Miyata, N. Nishiyama, K. Kataoka
    • Total Pages
      409
    • Publisher
      Eds., L. Huang, D. Liu, E. Wagner, Academic Press(Massachusetts, USA)
    • Description
      【発行確定】
    • Data Source
      KAKENHI-PROJECT-25000006
  • [Book] RNA Interference from Biology to Therapeutics (Advances in Delivery Science and Technology)2013

    • Author(s)
      (F. Pittella), K. Kataoka
    • Total Pages
      24
    • Publisher
      Springer US
    • Data Source
      KAKENHI-PROJECT-23350049
  • [Book] ナノテクノロジーの癌医療への応用 高分子ミセル型抗癌剤の開発、癌と化学療法36(3)2009

    • Author(s)
      西山伸宏、片岡一則
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Book] Advanced nanomaterials(Smart nanoassemblies of block copolymers for drug and gene delivery Eds., Ku.E.Geckeler, H.Nishide)2009

    • Author(s)
      H.Cabral, K.Kataoka
    • Publisher
      Germany
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Book] 超分子サイエンス&テクノロジー-基礎からイノベーションまで-(ナノバイオマテリアルと医療応用 国武豊喜監修)2009

    • Author(s)
      岸村顕広、片岡一則
    • Publisher
      株式会社エヌ・ティー・エス
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Book] 抗がん剤を運ぶシステム:高分子ミセル型DDS、現代化学(464)2009

    • Author(s)
      宮田完二郎、片岡一則
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Book] 細胞工学2008

    • Author(s)
      西山伸宏、片岡一則
    • Publisher
      人工ウイルスの実現に向けた高分子ミセル型ベクターの設計
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Book] ゲノム医学2007

    • Author(s)
      西山伸宏、片岡一則
    • Publisher
      分子標的治療薬とDDSの融合とのその可能性
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Book] レーザー研究2007

    • Author(s)
      西山伸宏、片岡一則
    • Publisher
      デンドリマー光増感剤を利用した部位選択的遺伝子導入
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Book] 呼吸と循環2007

    • Author(s)
      西山伸宏、鄭雄一、片岡一則
    • Publisher
      循環器疾患の治療のためのナノDDS
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Book] Mebio Oncology, 松村保広編、メジカルレビュー社2007

    • Author(s)
      西山伸宏、片岡一則
    • Publisher
      高分子ミセルを利用したがん標的治療
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Book] 高分子ナノキャリアを用いた遺伝子導入と再生医療への応用2007

    • Author(s)
      位高 啓史, 片岡 一則
    • Publisher
      メディカルレビュー(in press)
    • Data Source
      KAKENHI-PROJECT-17390412
  • [Book] 高分子2007

    • Author(s)
      西山伸宏、片岡一則
    • Publisher
      先端医療のためのインテリジェント型高分子ミセルの設計
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Book] 血管医学2007

    • Author(s)
      西山伸宏、片岡一則
    • Publisher
      ドラッグデリバリーシステム(DDS)と血管
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Book] インテリジェント高分子ミセルからのDDS2006

    • Author(s)
      Younsoo Bae, 片岡一則
    • Publisher
      最新医学(最新医学社)
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Book] 医学のためのナノ工学2006

    • Author(s)
      西山伸宏, 片岡一則
    • Total Pages
      6
    • Publisher
      日本臨床社
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Book] 高分子ミセル型ナノキャリアによるDDSとティッシュエンジニアリングへの応用2006

    • Author(s)
      位たか 啓史, 片岡 一則
    • Publisher
      日本医学館(In press)
    • Data Source
      KAKENHI-PROJECT-17390412
  • [Book] インテリジェント高分子ミセルからのDDS2006

    • Author(s)
      Younsoo Bae, 片岡一則
    • Publisher
      最新医学(最新医学社)
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Book] ナノキャリアによる遺伝子・siRNAデリバリー2006

    • Author(s)
      位たか 啓史, 鄭 雄一, 片岡 一則
    • Total Pages
      400
    • Publisher
      日本臨牀社
    • Data Source
      KAKENHI-PROJECT-17390412
  • [Book] Non-viral Gene Therapy : Gene Design and Delivery2005

    • Author(s)
      K.Taira, K.Kataoka, T.Niidome, Eds.
    • Publisher
      Springer-Verlag Tokyo, Tokyo, Japan(印刷中)
    • Data Source
      KAKENHI-PROJECT-14380391
  • [Book] Polymeric Drug Delivery Systems : Polymer Assemblies(Drugs and pharmaceutical science,Vol.143)2005

    • Author(s)
      Y.Bae, K.Kataoka
    • Total Pages
      530
    • Publisher
      Marcel Dekker(New York)
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Co-encapsulation of Cas9 mRNA and guide RNA in polyplex micelles enables genome editing in mouse brain2021

    • Author(s)
      S. Abbasi, S. Uchida, K. Toh, T.A. Tockary, A. Dirisala, K. Hayashi, S. Fukushima, K. Kataoka
    • Journal Title

      J. Control. Release

      Volume: 332 Pages: 260-268

    • DOI

      10.1016/j.jconrel.2021.02.026

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H03529, KAKENHI-PROJECT-19F19116, KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-18K18393
  • [Journal Article] Transient stealth coating of liver sinusoidal wall by anchoring two-armed PEG for retargeting nanomedicines2020

    • Author(s)
      Dirisala Anjaneyulu、Uchida Satoshi、Toh Kazuko、Li Junjie、Osawa Shigehito、Tockary Theofilus A.、Liu Xueying、Abbasi Saed、Hayashi Kotaro、Mochida Yuki、Fukushima Shigeto、Kinoh Hiroaki、Osada Kensuke、Kataoka Kazunori
    • Journal Title

      Science Advances

      Volume: 6 Issue: 26

    • DOI

      10.1126/sciadv.abb8133

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17KK0102, KAKENHI-PROJECT-18H03529, KAKENHI-PROJECT-19F19116, KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-18K18393
  • [Journal Article] Self‐Boosting Catalytic Nanoreactor Integrated with Triggerable Crosslinking Membrane Networks for Initiation of Immunogenic Cell Death by Pyroptosis2020

    • Author(s)
      Junjie Li, Yasutaka Anraku, Kazunori Kataoka
    • Journal Title

      Angewandte Chemie International Edition

      Volume: - Issue: 32 Pages: 13526-13530

    • DOI

      10.1002/anie.202004180

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17F17356, KAKENHI-PROJECT-20K20209
  • [Journal Article] Treatment of intervertebral disk disease by administration of messenger RNA encoding a cartilage-anabolic transcription factor.2019

    • Author(s)
      C. -Y. Lin, S. T. Crowley, S. Uchida, Y. Komaki, K. Kataoka, K. Itaka
    • Journal Title

      Mol. Ther. Nucleic Acids

      Volume: 16 Pages: 162-171

    • DOI

      10.1016/j.omtn.2019.02.012

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-15H03017, KAKENHI-PROJECT-18H03529, KAKENHI-PROJECT-17F17410, KAKENHI-PROJECT-16K10842, KAKENHI-PROJECT-19H03776, KAKENHI-PROJECT-20K20386
  • [Journal Article] Design concepts of polyplex micelles for in vivo therapeutic delivery of plasmid DNA and messenger RNA.2019

    • Author(s)
      S. Uchida, K. Kataoka
    • Journal Title

      J. Biomed. Mater. Res. A

      Volume: 107 Issue: 5 Pages: 978-990

    • DOI

      10.1002/jbm.a.36614

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-18H03529, KAKENHI-PROJECT-20K20386
  • [Journal Article] Glucose-linked sub-50-nm unimer polyion complex-assembled gold nanoparticles for targeted siRNA delivery to glucose transporter 1-overexpressing breast cancer stem-like cells.2019

    • Author(s)
      Y. Yi, H. J. Kim, M. Zheng, P. Mi, M. Naito, B. S. Kim, H. S. Min, K. Hayashi, F. Perche, K. Toh, X. Liu, Y. Mochida, H. Kinoh, H. Cabral, K. Miyata, K. Kataoka
    • Journal Title

      J. Control. Release

      Volume: 295 Pages: 268-277

    • DOI

      10.1016/j.jconrel.2019.01.006

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07234, KAKENHI-PROJECT-18K18378, KAKENHI-PROJECT-17H02098, KAKENHI-PROJECT-18H04170, KAKENHI-PROJECT-20K20386, KAKENHI-PROJECT-18K18391
  • [Journal Article] One-Pot Synthesis of PEG-Poly(amino acid) Block Copolymers Assembling Polymeric Micelles with PEG-Detachable Functionality2019

    • Author(s)
      Miyazaki Takuya、Igarashi Kazunori、Matsumoto Yu、Cabral Horacio
    • Journal Title

      ACS Biomaterials Science & Engineering

      Volume: - Issue: 11 Pages: 5727-5733

    • DOI

      10.1021/acsbiomaterials.8b01549

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-18K19901, KAKENHI-PROJECT-18H04170
  • [Journal Article] Induced packaging of mRNA into polyplex micelles by regulated hybridization with a small number of cholesteryl RNA oligonucleotides directed enhanced in vivo transfection.2019

    • Author(s)
      N. Yoshinaga, S. Uchida, M. Naito, K. Osada, H. Cabral, K. Kataoka
    • Journal Title

      Biomaterials

      Volume: 197 Pages: 255-267

    • DOI

      10.1016/j.biomaterials.2019.01.023

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-17KK0102, KAKENHI-PROJECT-16H03178, KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-18H03529, KAKENHI-PROJECT-18K19901, KAKENHI-PROJECT-20K20386, KAKENHI-PROJECT-18J14336
  • [Journal Article] Glucose transporter 1-mediated vascular translocation of nanomedicines enhances accumulation and efficacy in solid tumors2019

    • Author(s)
      Suzuki Kazumi、Miura Yutaka、Mochida Yuki、Miyazaki Takuya、Toh Kazuko、Anraku Yasutaka、Melo Vinicio、Liu Xueying、Ishii Takehiko、Nagano Osamu、Saya Hideyuki、Cabral Horacio、Kataoka Kazunori
    • Journal Title

      Journal of Controlled Release

      Volume: 301 Pages: 28-41

    • DOI

      10.1016/j.jconrel.2019.02.021

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-16H05422, KAKENHI-PROJECT-17H04742, KAKENHI-PROJECT-17K20094, KAKENHI-PROJECT-18H04170, KAKENHI-PROJECT-20K20386
  • [Journal Article] Tuned Density of Anti-Tissue Factor Antibody Fragment onto siRNA-Loaded Polyion Complex Micelles for Optimizing Targetability into Pancreatic Cancer Cells2018

    • Author(s)
      Min Hyun Su、Kim Hyun Jin、Ahn Jooyeon、Naito Mitsuru、Hayashi Kotaro、Toh Kazuko、Kim Beob Soo、Matsumura Yasuhiro、Kwon Ick Chan、Miyata Kanjiro、Kataoka Kazunori
    • Journal Title

      Biomacromolecules

      Volume: 19 Issue: 6 Pages: 2320-2329

    • DOI

      10.1021/acs.biomac.8b00507

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H04170
  • [Journal Article] Designing immunostimulatory double stranded messenger RNA with maintained translational activity through hybridization with poly A sequences for effective vaccination2018

    • Author(s)
      Uchida Satoshi、Yoshinaga Naoto、Yanagihara Kayoko、Yuba Eiji、Kataoka Kazunori、Itaka Keiji
    • Journal Title

      Biomaterials

      Volume: 150 Pages: 162-170

    • DOI

      10.1016/j.biomaterials.2017.09.033

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-15H03024, KAKENHI-PROJECT-15K20962, KAKENHI-PROJECT-25000006
  • [Journal Article] Block Copolymer Micelles in Nanomedicine Applications2018

    • Author(s)
      Cabral Horacio、Miyata Kanjiro、Osada Kensuke、Kataoka Kazunori
    • Journal Title

      Chemical Reviews

      Volume: 118 Issue: 14 Pages: 6844-6892

    • DOI

      10.1021/acs.chemrev.8b00199

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17KK0102, KAKENHI-PROJECT-16H03178, KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-17H02098, KAKENHI-PROJECT-18H04170, KAKENHI-PROJECT-20K20386
  • [Journal Article] Enhanced intracellular delivery of siRNA by controlling ATP-responsivity of phenylboronic acid-functionalized polyion complex micelles.2018

    • Author(s)
      M. Naito, N. Yoshinaga, T. Ishii, A. Matsumoto, Y. Miyahara, K. Miyata, K. Kataoka
    • Journal Title

      Macromol. Biosci.

      Volume: 1 Issue: 1

    • DOI

      10.1002/mabi.201700357

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25000006
  • [Journal Article] Systemic Delivery of Folate-PEG siRNA Lipopolyplexes with Enhanced Intracellular Stability for In Vivo Gene Silencing in Leukemia2017

    • Author(s)
      Lee Dian-Jang、Kessel Eva、Lehto Taavi、Liu Xueying、Yoshinaga Naoto、Padari K?rt、Chen Ying-Chen、Kempter Susanne、Uchida Satoshi、R?dler Joachim O.、Pooga Margus、Sheu Ming-Thau、Kataoka Kazunori、Wagner Ernst
    • Journal Title

      Bioconjugate chemistry

      Volume: 28 Issue: 9 Pages: 2393-2409

    • DOI

      10.1021/acs.bioconjchem.7b00383

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-15K20962, KAKENHI-PROJECT-25000006
  • [Journal Article] Unilamellar polyion complex vesicles (PICsomes) with tunable permeabilities for macromolecular solutes with different shapes and sizes2017

    • Author(s)
      Mutaf Omer F.、Anraku Yasutaka、Kishimura Akihiro、Kataoka Kazunori
    • Journal Title

      Polymer

      Volume: 133 Pages: 1-7

    • DOI

      10.1016/j.polymer.2017.10.062

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K20109, KAKENHI-PROJECT-25000006
  • [Journal Article] Improved brain expression of anti-amyloid β scFv by complexation of mRNA including a secretion sequence with PEG-based block catiomer.2017

    • Author(s)
      F. Perche, S. Uchida, H. Akiba, C.-Y. Lin, M. Ikegami, A. Disrala, T. Nakashima, K. Itaka, K. Tsumoto, K. Kataoka
    • Journal Title

      Curr. Alzheimer Res.

      Volume: 14 Issue: 3 Pages: 295-302

    • DOI

      10.2174/1567205013666161108110031

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K20962, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-16H02420
  • [Journal Article] A facile amino-functionalization of poly (2-oxazoline) s' distal end through sequential azido end-capping and Staudinger reactions.2017

    • Author(s)
      S. Osawa, T. Ishii, H. Takemoto, K. Osada, K. Kataoka
    • Journal Title

      Eur. Polym. J.

      Volume: 88 Pages: 553-561

    • DOI

      10.1016/j.eurpolymj.2016.11.029

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-16H03178
  • [Journal Article] Effect of shear stress on structure and function of polyplex micelle from poly(ethylene glycol)-poly(L-lysine) block copolymers as systemic gene delivery carrier2017

    • Author(s)
      K. M. Takeda, Y. Yamasaki, S. Ikeda, A. Dirisala, T. A. Tockary, K. Toh, K. Osada, K. Kataoka
    • Journal Title

      Biomaterials

      Volume: 126 Pages: 31-38

    • DOI

      10.1016/j.biomaterials.2017.02.012

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-14J11005, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-16H03178
  • [Journal Article] Multilayered polyion complexes with dissolvable silica layer covered by controlling densities of cRGD-conjugated PEG chains for cancer-targeted siRNA delivery.2017

    • Author(s)
      M. Naito, R. Azuma, H. Takemoto, M. Hori, N. Yoshinaga, S. Osawa, R. Kamegawa, H. -J. Kim, T. Ishii, N. Nishiyama, K. Miyata, K. Kataoka
    • Journal Title

      J. Biomater. Sci. Polym.

      Volume: 28 Issue: 10-12 Pages: 1109-1123

    • DOI

      10.1080/09205063.2017.1301775

    • Description
      【掲載確定】 in press
    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-15H04635, KAKENHI-PROJECT-16F16058, KAKENHI-PROJECT-16F16407, KAKENHI-PROJECT-16K15104, KAKENHI-PROJECT-25282141
  • [Journal Article] Therapeutic Vesicular Nanoreactors with Tumor-Specific Activation and Self-Destruction for Synergistic Tumor Ablation2017

    • Author(s)
      Li Junjie、Dirisala Anjaneyulu、Ge Zhishen、Wang Yuheng、Yin Wei、Ke Wendong、Toh Kazuko、Xie Jinbing、Matsumoto Yu、Anraku Yasutaka、Osada Kensuke、Kataoka Kazunori
    • Journal Title

      Angew Chem Int Ed Engl

      Volume: 56 Issue: 45 Pages: 14025-14030

    • DOI

      10.1002/anie.201706964

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17KT0048, KAKENHI-PROJECT-16K11226, KAKENHI-PROJECT-16H03178, KAKENHI-PROJECT-15K12536, KAKENHI-PROJECT-25000006
  • [Journal Article] Glycaemic control boosts glucosylated nanocarrier crossing the BBB into the brain2017

    • Author(s)
      Anraku Y.、Kuwahara H.、Fukusato Y.、Mizoguchi A.、Ishii T.、Nitta K.、Matsumoto Y.、Toh K.、Miyata K.、Uchida S.、Nishina K.、Osada K.、Itaka K.、Nishiyama N.、Mizusawa H.、Yamasoba T.、Yokota T.、Kataoka K.
    • Journal Title

      Nat Commun

      Volume: 8 Issue: 1 Pages: 2001-2009

    • DOI

      10.1038/s41467-017-00952-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17KT0048, KAKENHI-PROJECT-16K11226, KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-15H04635, KAKENHI-PROJECT-15H04813, KAKENHI-PROJECT-16H03178, KAKENHI-PROJECT-17H04742, KAKENHI-PROJECT-16F16058, KAKENHI-PROJECT-16F16407, KAKENHI-PROJECT-16K15104, KAKENHI-PROJECT-15K20962, KAKENHI-PROJECT-25000006
  • [Journal Article] Block copolymer-boron cluster conjugate for effective boron neutron capture therapy of solid tumors.2017

    • Author(s)
      P. Mi, H. Yanagie, N. Dewi, H.-C. Yen, X. Liu, M. Suzuki, Y. Sakurai, K. Ono, H. Takahashi, H. Cabral, K. Kataoka,
    • Journal Title

      J. Control. Release

      Volume: 254 Pages: 1-9

    • DOI

      10.1016/j.jconrel.2017.03.036

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-25293267, KAKENHI-PROJECT-15H04635, KAKENHI-PROJECT-16F16058, KAKENHI-PROJECT-16F16407, KAKENHI-PROJECT-16K15104, KAKENHI-PROJECT-15K12534
  • [Journal Article] Virus-mimicking chimaeric polymersomes boost targeted cancer siRNA therapy in vivo.2017

    • Author(s)
      Y. Zou, M. Zheng, W. Yang, F. Meng, K. Miyata, H. -J. Kim, K. Kataoka, Z. Zhong
    • Journal Title

      Adv. Mater.

      Volume: 29 Issue: 42 Pages: 1703285-1703285

    • DOI

      10.1002/adma.201703285

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25000006
  • [Journal Article] Nanoparticle delivery of Cas9 ribonucleoprotein and donor DNA in vivo induces homology-directed DNA repair.2017

    • Author(s)
      K. Lee, M. Conboy, H. -M. Park, F. Jiang, H. -J. Kim, M. A. Dewitt, V. A. Mackley, K. Chang, A. Rao, C. Skinner, T. Shobha, M. Mehdipour, H. Liu, W. -C. Huang, F. Lan, N. L. Bray, S. Li, J. E. Corn, K. Kataoka, J. A. Doudna, I. Conboy, N. Murthy
    • Journal Title

      Nat. Biomed. Eng.

      Volume: 1 Issue: 11 Pages: 889-901

    • DOI

      10.1038/s41551-017-0137-2

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25000006
  • [Journal Article] Polymeric micelles for targeted tumor therapy of platinum anticancer drugs2017

    • Author(s)
      Y. Mochida, H. Cabral, K. Kataoka
    • Journal Title

      Expert Opin. Drug Deliv.

      Volume: -

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K12534
  • [Journal Article] Poly(ethylene glycol) crowding as critical factor to determine pDNA packaging scheme into polyplex micelles for enhanced gene expression2017

    • Author(s)
      K. M. Takeda, K. Osada, T. A. Tockary, A. Dirisala, Q. Chen, K. Kataoka
    • Journal Title

      Biomacromolecules

      Volume: 18 Issue: 1 Pages: 36-43

    • DOI

      10.1021/acs.biomac.6b01247

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-14J11005, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-16H03178
  • [Journal Article] Polyplex Micelles with Phenylboronate/Gluconamide Cross-Linking in the Core Exerting Promoted Gene Transfection through Spatiotemporal Responsivity to Intracellular pH and ATP Concentration2017

    • Author(s)
      Yoshinaga Naoto、Ishii Takehiko、Naito Mitsuru、Endo Taisuke、Uchida Satoshi、Cabral Horacio、Osada Kensuke、Kataoka Kazunori
    • Journal Title

      Journal of the American Chemical Society

      Volume: 139 Issue: 51 Pages: 18567-18575

    • DOI

      10.1021/jacs.7b08816

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-16H03178, KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-15K20962, KAKENHI-PROJECT-25000006
  • [Journal Article] In vivo evaluation of neutron capture therapy effectivity using calcium phosphate-based nanoparticles as Gd-DTPA delivery agent2016

    • Author(s)
      Novriana Dewi, Peng Mi, Hironobu Yanagie, Yuriko Sakurai, Yasuyuki Morishita, Masashi Yanagawa, Takayuki Nakagawa, Atsuko Shinohara, Takehisa Matsukawa, Kazuhito Yokoyama, Horacio Cabral, Minoru Suzuki, Yoshinori Sakurai, Hiroki Tanaka, Koji Ono, Nobuhiro Nishiyama, Kazunori Kataoka, Hiroyuki Takahashi
    • Journal Title

      Journal of Cancer Research and Clinical Oncology

      Volume: 142 Issue: 4 Pages: 767-775

    • DOI

      10.1007/s00432-015-2085-0

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K12534, KAKENHI-PROJECT-25670571, KAKENHI-PROJECT-25293267
  • [Journal Article] Screening of mRNA chemical modification to maximize protein expression with reduced immunogenicity.2016

    • Author(s)
      S. Uchida, K. Kataoka, K. Itaka
    • Journal Title

      Pharmaceutics

      Volume: 7 Issue: 3 Pages: 137-151

    • DOI

      10.3390/pharmaceutics7030137

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K20962, KAKENHI-PROJECT-15H03017, KAKENHI-PROJECT-25000006
  • [Journal Article] Enhanced Efficacy against Cervical Carcinomas through Polymeric Micelles Physically Incorporating the Proteasome Inhibitor MG132.2016

    • Author(s)
      Matsumoto Y, Miyamoto Y, Cabral H, Matsumoto Y, Nagasaka K, Nakagawa S, Yano T, Maeda D, Oda K, Kawana K, Nishiyama N, Kataoka K, Fujii T
    • Journal Title

      Cancer Sci

      Volume: in press Issue: 6 Pages: 773-781

    • DOI

      10.1111/cas.12926

    • NAID

      120007089072

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462515, KAKENHI-PROJECT-26670738, KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-16K11226, KAKENHI-PROJECT-15H04635, KAKENHI-PROJECT-16K15104, KAKENHI-PROJECT-15K12534
  • [Journal Article] Recent progress in development of siRNA delivery vehicles for cancer therapy.2016

    • Author(s)
      H. -J. Kim, A. Kim, K. Miyata, K. Kataoka
    • Journal Title

      Adv. Drug Deliv. Rev.

      Volume: 104 Pages: 61-77

    • DOI

      10.1016/j.addr.2016.06.011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25000006
  • [Journal Article] Intracellular Delivery of Charge-Converted Monoclonal Antibodies by Combinatorial Design of Block/Homo Polyion Complex Micelles2016

    • Author(s)
      Ahram Kim, Yutaka Miura, Takehiko Ishii, Omer F. Mutaf, Nobuhiro Nishiyama, Horacio Cabral, Kazunori Kataoka
    • Journal Title

      Biomacromolecules

      Volume: 17 Issue: 2 Pages: 446-453

    • DOI

      10.1021/acs.biomac.5b01335

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K12534, KAKENHI-PROJECT-15H04635, KAKENHI-PROJECT-24689051
  • [Journal Article] Targeted systemic delivery of siRNA to cervical cancer model using cyclic RGD-installed unimer polyion complex-assembled gold nanoparticles2016

    • Author(s)
      Yi, Y., Kim, H. J., Mi, P., Zheng, M., Takemoto, H., Toh, K., Kim, B. S., Hayashi, K., Naito, M., Matsumoto, Y., Miyata, K., Kataoka, K.
    • Journal Title

      J Control Release

      Volume: 244 Pages: 247-256

    • DOI

      10.1016/j.jconrel.2016.08.041

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K11226, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25282141
  • [Journal Article] Messenger RNA-based therapeutics for brain diseases: An animal study for augmenting clearance of beta-amyloid by intracerebral administration of neprilysin mRNA loaded in polyplex nanomicelles2016

    • Author(s)
      Lin CY, Perche F, Ikegami M, Uchida S, Kataoka K, Itaka K
    • Journal Title

      J Control Release

      Volume: 235 Pages: 268-275

    • DOI

      10.1016/j.jconrel.2016.06.001

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H03017, KAKENHI-PROJECT-14F04406, KAKENHI-PROJECT-15K20962, KAKENHI-PROJECT-25000006
  • [Journal Article] Targeting the Notch-regulated non-coding RNA TUG1 for glioma treatment.2016

    • Author(s)
      Katsushima K, Natsume A, Ohka F, Shinjo K, Hatanaka A, Ichimura N, Sato S, Takahashi S, Kimura H, Totoki Y, Shibata T, Naito M, Kim HJ, Miyata K, Kataoka K, Kondo Y.
    • Journal Title

      Nat Commun.

      Volume: 7 Issue: 1 Pages: 13616-13616

    • DOI

      10.1038/ncomms13616

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25290048, KAKENHI-PROJECT-26430136, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25282141
  • [Journal Article] Synthetic polyamines to regulate mRNA translation through the preservative binding of eukaryotic initiation factor 4E to the cap structure.2016

    • Author(s)
      H. Uchida, K. Itaka, S. Uchida, T. Ishii, T. Suma, K. Miyata, M. Oba, N. Nishiyama, K. Kataoka
    • Journal Title

      J. Am. Chem. Soc.

      Volume: 138 Issue: 5 Pages: 1478-1481

    • DOI

      10.1021/jacs.5b11726

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K20962, KAKENHI-PROJECT-15H03017, KAKENHI-PROJECT-25000006
  • [Journal Article] Polyplex micelles with double-protective compartments of hydrophilic shell and thermo-switchable palisade of poly (oxazoline)-based block copolymers for promoted gene transfection.2016

    • Author(s)
      S. Osawa, K. Osada, S. Hiki, A. Dirisala, T. Ishii, K. Kataoka
    • Journal Title

      Biomacromolecules

      Volume: 17 Issue: 1 Pages: 354-361

    • DOI

      10.1021/acs.biomac.5b01456

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25000006
  • [Journal Article] Lipid- and polyion complex-based micelles as agonist platforms for TNFR superfamily receptors2016

    • Author(s)
      R. N. Gilbreth, S. Novarra, L. Wetzel, S. Florinas, H. Cabral, K. Kataoka, J. RiosDoria, R. J. Christie, M. Baca
    • Journal Title

      J. Control. Release

      Volume: 230 Pages: 104-114

    • DOI

      10.1016/j.jconrel.2016.05.041

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-15K12534
  • [Journal Article] Influence of RNA strand rigidity on polyion complex formation with block catiomers.2016

    • Author(s)
      K. Hayashi, H. Chaya, S. Fukushima, S. Watanabe, H. Takemoto, K. Osada, N. Nishiyama, K. Miyata, K. Kataoka
    • Journal Title

      Macromol. Rapid Commun.

      Volume: 37 Issue: 6 Pages: 486-493

    • DOI

      10.1002/marc.201500661

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K16331, KAKENHI-PROJECT-14J10626, KAKENHI-PROJECT-24659411, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25282141
  • [Journal Article] Vascular bursts enhance permeability of tumour blood vessels and improve nanoparticle delivery2016

    • Author(s)
      Yu Matsumoto, Joseph W. Nichols, Kazuko Toh, Takahiro Nomoto, Horacio Cabral, Yutaka Miura, R. James Christie, Naoki Yamada, Tadayoshi Ogura, Mitsunobu R. Kano, Yasuhiro Matsumura, Nobuhiro Nishiyama, Tatsuya Yamasoba, You Han Bae, Kazunori Kataoka
    • Journal Title

      Nature Nanotechnology

      Volume: - Issue: 6 Pages: 533-538

    • DOI

      10.1038/nnano.2015.342

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K12534, KAKENHI-PROJECT-26670738, KAKENHI-PROJECT-26293119, KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-16K11226
  • [Journal Article] Enhanced target recognition of nanoparticles by cocktail PEGylation with chains of varying lengths.2016

    • Author(s)
      T. Ishii, K. Miyata, Y. Anraku, M. Naito, Y. Yi, T. Jinbo, S. Takae, Y. Fukusato, M. Hori, K. Osada, K. Kataoka
    • Journal Title

      Chem. Commun.

      Volume: 52 Pages: 1517-1519

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25000006
  • [Journal Article] Rod-to-Globule Transition of pDNA/PEG-Poly(L-Lysine) Polyplex Micelles Induced by a Collapsed Balance Between DNA Rigidity and PEG Crowdedness2016

    • Author(s)
      Tockary TA, Osada K, Motoda Y, Hiki S, Chen Q, Takeda KM, et al.
    • Journal Title

      Small

      Volume: 12(9) Issue: 9 Pages: 1193-1200

    • DOI

      10.1002/smll.201501815

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-14J11005, KAKENHI-PROJECT-25000006
  • [Journal Article] Nanomedicines eradicating cancer stem-like cells in vivo by pH-triggered intracellular cooperative action of loaded drugs.2016

    • Author(s)
      H. Kinoh, Y. Miura, T. Chida, X. Liu, K. Mizuno, S. Fukushima, Y. Morodomi, N. Nishiyama, H. Cabral, K. Kataoka
    • Journal Title

      ACS Nano

      Volume: 10 Issue: 6 Pages: 5643-5655

    • DOI

      10.1021/acsnano.6b00900

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-15H04635, KAKENHI-PROJECT-16K15104, KAKENHI-PROJECT-15K12534
  • [Journal Article] Messenger RNA delivery of a cartilage-anabolic transcription factor as a disease-modifying strategy for osteoarthritis treatment.2016

    • Author(s)
      1.Aini H, Itaka K, Fujisawa A, Uchida H, Uchida S, Fukushima S, Kataoka K, Saito T, Chung UI, Ohba S.
    • Journal Title

      Sci Rep.

      Volume: 6 Issue: 1 Pages: 18743-18743

    • DOI

      10.1038/srep18743

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462285, KAKENHI-PROJECT-26670859, KAKENHI-PROJECT-15K20962, KAKENHI-PROJECT-15H03017, KAKENHI-PROJECT-25293316, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25253087, KAKENHI-PROJECT-15K15535, KAKENHI-PROJECT-26293330
  • [Journal Article] A pH-activatable nanoparticle with signal-amplification capabilities for non-invasive imaging of tumour malignancy.2016

    • Author(s)
      P. Mi, D. Kokuryo, H. Cabral, H. Wu, Y. Terada, T. Saga, I. Aoki, N. Nishiyama, K. Kataoka,
    • Journal Title

      Nat. Nanotechnol.

      Volume: 11 Issue: 8 Pages: 724-730

    • DOI

      10.1038/nnano.2016.72

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-24300167, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-15H04635, KAKENHI-PROJECT-16K15104, KAKENHI-PROJECT-26293295, KAKENHI-PROJECT-15K12534
  • [Journal Article] Eradication of CD44-variant positive population in head and neck tumors through controlled intracellular navigation of cisplatin-loaded nanomedicines2016

    • Author(s)
      Ming Wang, Yutaka Miura, Kenji Tsuchihashi, Kazuki Miyano, Osamu Nagano, Momoko Yoshikawa, Ami Tanabe, Jun Makino, Yuki Mochida, Nobuhiro Nishiyama, Hideyuki Saya, Horacio Cabral, Kazunori Kataoka
    • Journal Title

      Journal of Controlled Release

      Volume: 230 Pages: 26-33

    • DOI

      10.1016/j.jconrel.2016.03.038

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K12534, KAKENHI-PROJECT-26861579, KAKENHI-PROJECT-16K20613
  • [Journal Article] cRGD-installed polymeric micelles loading platinum anticancer drugs enable cooperative treatment against lymph node metastasis2016

    • Author(s)
      Jun Makino, Horacio Cabral, Yutaka Miura, Yu Matsumoto, Ming Wang, Hiroaki Kinoh, Yuki Mochida, Nobuhiro Nishiyama, Kazunori Kataoka
    • Journal Title

      Journal of Controlled Release

      Volume: 220 PartB Pages: 783-791

    • DOI

      10.1016/j.jconrel.2015.10.017

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K12534, KAKENHI-PROJECT-15H04635, KAKENHI-PROJECT-26670738, KAKENHI-PROJECT-24689051
  • [Journal Article] Hydroxychloroquine-conjugated gold nanoparticles for improved siRNA activity2016

    • Author(s)
      Federico Perche, Yu Yi, Louise Hespel, Peng Mi, Anjaneyulu Dirisala, Horacio Cabral, Kanjiro Miyata, Kazunori Kataoka
    • Journal Title

      Biomaterials

      Volume: 90 Pages: 62-71

    • DOI

      10.1016/j.biomaterials.2016.02.027

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K12534, KAKENHI-PROJECT-14F04352, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25282141
  • [Journal Article] Systemic delivery of messenger RNA for the treatment of pancreatic cancer using polyplex nanomicelles with a cholesterol moiety.2016

    • Author(s)
      S. Uchida, H. Kinoh, T. Ishii, A. Matsui, T. A. Tockary, K. M. Takeda, H. Uchida, K. Osada, K. Itaka, K. Kataoka
    • Journal Title

      Biomaterials

      Volume: 82 Pages: 221-228

    • DOI

      10.1016/j.biomaterials.2015.12.031

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K20962, KAKENHI-PROJECT-15H03017, KAKENHI-PROJECT-14J11005, KAKENHI-PROJECT-25000006
  • [Journal Article] A Nanoparticle platform to evaluate bioconjugation and receptor-mediated cell uptake using crosslinked polyion complex micelles bearing antibody fragments2016

    • Author(s)
      Stelios Florinas, Marc Liu, Ryan Fleming, Lilian Van Vlerken-Ysla, Joanne Ayriss, Ryan Gilbreth, Nazzareno Dimasi, Changshou Gao, Herren Wu, Ze-Qi Xu, Shanoyi Chen, Anjaneyulu Dirisala, Kazunori Kataoka, Horacio Cabral, R. James Christie
    • Journal Title

      Biomacromolecules

      Volume: 17 Issue: 5 Pages: 1818-1833

    • DOI

      10.1021/acs.biomac.6b00239

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K12534
  • [Journal Article] Polyplex micelle installing intracellular self-processing functionalities without free catiomers for safe and efficient systemic gene therapy through tumor vasculature targeting2016

    • Author(s)
      Q. Chen, K. Osada, Z. Ge, S. Uchida, T. A. Tockary, A. Dirisala, A. Matsui, K. Toh, K. M. Takeda, X. Liu, T. Nomoto, T. Ishii, M. Oba, Y. Matsumoto, K. Kataoka
    • Journal Title

      Biomaterials

      Volume: 113 Pages: 253-265

    • DOI

      10.1016/j.biomaterials.2016.10.042

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-14J11005, KAKENHI-PROJECT-15K20962, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-17KT0048, KAKENHI-PROJECT-16K11226, KAKENHI-PROJECT-16H03178
  • [Journal Article] Messenger RNA-based therapeutics for the treatment of apoptosis-associated diseases.2015

    • Author(s)
      A. Matsui, S. Uchida, T. Ishii, K. Itaka, K. Kataoka
    • Journal Title

      Scientific Reports

      Volume: 5 Issue: 1 Pages: 15810-15810

    • DOI

      10.1038/srep15810

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K20962, KAKENHI-PROJECT-15H03017, KAKENHI-PROJECT-25000006
  • [Journal Article] Intrathecal injection of a therapeutic gene-containing polyplex to treat spinal cord injury.2015

    • Author(s)
      Hayakawa K, Uchida S, Ogata T, Tanaka S, Kataoka K, Itaka K.
    • Journal Title

      J Control Release

      Volume: 197 Pages: 1-9

    • DOI

      10.1016/j.jconrel.2014.10.027

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24300170, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25882011
  • [Journal Article] DNA/RNA Heteroduplex Oligonucleotide for Highly Efficient Gene Silencing.2015

    • Author(s)
      Nishina K., Piao W., Yoshida-Tanaka K., Sujino Y., Nishina T., Yamamoto T., Nitta K, Yoshioka K, Kuwahara H., Yasuhara H., Baba T., Ono F., Miyata K, Miyake K., P. Seth P., Low A., Yoshida M., Bennett C.F., Kataoka K., Mizusawa H., Obika S. Yokota T.
    • Journal Title

      Nature Commun.

      Volume: 6 Issue: 1 Pages: 7969-7969

    • DOI

      10.1038/ncomms8969

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24249007, KAKENHI-PROJECT-25000006
  • [Journal Article] A tadpole-shaped gene carrier with distinct phase segregation in a ternary polymeric micelle2015

    • Author(s)
      Chen Q, Osada K, Pennisi M, Uchida S, Tockary TA, Dirisala A, Li Y, Takeda KM, Oniyanagi S, Itaka K, Kataoka K
    • Journal Title

      Soft Matter

      Volume: 11 Issue: 14 Pages: 2718-2722

    • DOI

      10.1039/c4sm02850c

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-14J11005, KAKENHI-PROJECT-24300170, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25882011
  • [Journal Article] Toroidal packaging of pDNA into block ionomer micelles exerting promoted in vivo gene expression.2015

    • Author(s)
      Y. Li, K. Osada, Q. Chen, T. A. Tockary, A. Dirisala, K. M. Takeda, S. Uchida, K. Nagata, K. Itaka, K. Kataoka
    • Journal Title

      Biomacromolecules

      Volume: 16 Issue: 9 Pages: 2664-2671

    • DOI

      10.1021/acs.biomac.5b00491

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K20962, KAKENHI-PROJECT-14J11005, KAKENHI-PROJECT-25000006
  • [Journal Article] Regulated protonation of polyaspartamide derivatives bearing repeated aminoethylene side chains for efficient intracellular siRNA delivery with minimal cytotoxicity2015

    • Author(s)
      H. Gao, H. Takemoto, Q. Chen, M. Naito, H. Uchida, X. Liu, K. Miyata, K. Kataoka
    • Journal Title

      Chemical Communications

      Volume: 51 Issue: 15 Pages: 3158-3161

    • DOI

      10.1039/c4cc09859e

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-15K16331
  • [Journal Article] Polymeric Micelle Platform for Multimodal Tomographic Imaging to Detect Scirrhous Gastric Cancer2015

    • Author(s)
      Yutaka Miura, Atsushi B. Tsuji, Aya Sugyo, Hitomi Sudo, Ichio Aoki, Masayuki Inubushi, Masakazu Yashiro, Kosei Hirakawa, Horacio Cabral, Nobuhiro Nishiyama, Tsuneo Saga, Kazunori Kataoka
    • Journal Title

      ACS Biomaterials Science & Engineering

      Volume: 1 Issue: 11 Pages: 1067-1076

    • DOI

      10.1021/acsbiomaterials.5b00142

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K12534, KAKENHI-PROJECT-24300167, KAKENHI-PROJECT-24689051
  • [Journal Article] Feasibility of a subcutaneously administered block/homo-mixed polyplex micelle as a carrier for DNA vaccination in a mouse tumor model.2015

    • Author(s)
      Cui L, Osada K, Imaizumi A, Kataoka K, Nakano K
    • Journal Title

      J Control Release

      Volume: 206 Pages: 220-231

    • DOI

      10.1016/j.jconrel.2015.03.029

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24390322
  • [Journal Article] Treatment of neurological disorders by introducing mRNA in vivo using polyplex nanomicelles2015

    • Author(s)
      Baba M, Itaka K, Kondo K, Yamasoba T, Kataoka K.
    • Journal Title

      J Control Release

      Volume: 201 Pages: 41-48

    • DOI

      10.1016/j.jconrel.2015.01.017

    • NAID

      120006348466

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24300170, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-26293366
  • [Journal Article] Intraperitoneal transduction of tumor-associated antigen, CD40L and GM-CSF genes by polyplex micelle elicits vaccine effect in mouse tumor models.2014

    • Author(s)
      Furugaki K, Cui L, Kunisawa Y, Shinkai K, Tanaka M, Kataoka K, Nakano K
    • Journal Title

      Plos One

      Volume: 9(7) Issue: 7 Pages: e101854-e101854

    • DOI

      10.1371/journal.pone.0101854

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24390322
  • [Journal Article] Precise engineering of siRNA delivery vehicles to tumors using polyion complexes and gold nanoparticles2014

    • Author(s)
      H. -J. Kim, H. Takemoto, Y. Yi, M. Zheng, Y. Maeda, H. Chaya, K. Hayashi, P. Mi, F. Pittella, R. J. Christie, K. Toh, Y. Matsumoto, N. Nishiyama, K. Miyata, K. Kataoka
    • Journal Title

      ACS Nano

      Volume: 8 Issue: 9 Pages: 8979-8991

    • DOI

      10.1021/nn502125h

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-13F03349, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25282141, KAKENHI-PROJECT-26670738
  • [Journal Article] siRNA delivery from triblock copolymer micelles with spatially-ordered compartmants of PEG shell, siRNA-loaded intermediate layer, and hydrophobic core2014

    • Author(s)
      Hyun Jin Kim, Kanjiro Miyata, Takahiro Nomoto, Meng Zheng, Ahram Kim, Xueying Liu, Horacio Cabral, R. James Christie, Nobuhiro Nishiyama, Kazunori Kataoka
    • Journal Title

      Biomaterials

      Volume: 35 Issue: 15 Pages: 4548-4556

    • DOI

      10.1016/j.biomaterials.2014.02.016

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-13F03349, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25282141, KAKENHI-PROJECT-25670010, KAKENHI-PROJECT-25750172
  • [Journal Article] Targeted gene delivery by polyplex micelles with crowded PEG palisade and cRGD moiety for systemic treatment of pancreatic tumors2014

    • Author(s)
      Z. Ge, Q. Chen, K. Osada, X. Liu, T. A. Tockary, S. Uchida, A. Dirisala, T. Ishii, T. Nomoto, K. Toh, Y. Matsumoto, M. Oba, M. R. Kano, K. Itaka, K. Kataoka
    • Journal Title

      Biomaterials

      Volume: 35 Issue: 10 Pages: 3416-3426

    • DOI

      10.1016/j.biomaterials.2013.12.086

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790043, KAKENHI-PROJECT-23790433, KAKENHI-PROJECT-24300170, KAKENHI-PROJECT-24790530, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25882011, KAKENHI-PROJECT-26293119, KAKENHI-PROJECT-26670738
  • [Journal Article] Actively-targeted polyion complex micelles stabilized by cholesterol and disulfide cross-linking for systemic delivery of siRNA to solid tumors2014

    • Author(s)
      Y. Oe, R. J. Christie, M. Naito, S. A. Low, S. Fukushima, K. Toh, Y. Miura, Y. Matsumoto, N. Nishiyama, K. Miyata, K. Kataoka
    • Journal Title

      Biomaterials

      Volume: 35 Issue: 27 Pages: 7887-7895

    • DOI

      10.1016/j.biomaterials.2014.05.041

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-24659584, KAKENHI-PROJECT-24689051, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25282141, KAKENHI-PROJECT-26670738
  • [Journal Article] Optimized rod length of polyplex micelles for maximizing transfection efficiency and their performance in systemic gene therapy against stroma-rich pancreatic tumors2014

    • Author(s)
      Dirisala A, Osada K, Chen Q, Tockary TA, Machitani K, Osawa S, Liu X, Ishii T, Miyata K, Oba M, Uchida S, Itaka K, Kataoka K
    • Journal Title

      Biomaterials

      Volume: 35(20) Issue: 20 Pages: 5359-5368

    • DOI

      10.1016/j.biomaterials.2014.03.037

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-14J11005, KAKENHI-PROJECT-24300170, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25882011
  • [Journal Article] Multifunctional polyion complex micelle featuring enhanced stability, targetability, and endosome escapability for systemic siRNA delivery to subcutaneous model of lung cancer2014

    • Author(s)
      Hyun Jin Kim, Takehiko Ishii, Meng Zheng, Sumiyo Watanabe, Kazuko Toh, Yu Matsumoto, Nobuhiro Nishiyama, Kanjiro Miyata, Kazunori Kataoka
    • Journal Title

      Drug Delivery and Translational Research

      Volume: 4 Issue: 1 Pages: 50-60

    • DOI

      10.1007/s13346-013-0175-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-13F03349, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-23790043, KAKENHI-PROJECT-24659411, KAKENHI-PROJECT-24790530, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25282141, KAKENHI-PROJECT-26670738
  • [Journal Article] Systemic siRNA delivery to a spontaneous pancreatic tumor model in transgenic mice by PEGylated calcium phosphate hybrid micelles2014

    • Author(s)
      F. Pittella, N. Nishiyama, et al.
    • Journal Title

      J. Control. Release

      Volume: 178 Pages: 18-24

    • DOI

      10.1016/j.jconrel.2014.01.008

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-13F03042, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-24659411, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25282141, KAKENHI-PROJECT-25670010, KAKENHI-PROJECT-25750172
  • [Journal Article] Muscle-targeted hydrodynamic gene introduction of insulin-like growth factor-1 using polyplex nanomicelle to treat peripheral nerve injury.2014

    • Author(s)
      Nagata K, Itaka K, Baba M, Uchida S, Ishii T, Kataoka K.
    • Journal Title

      J Control Release

      Volume: 183C Pages: 27-34

    • DOI

      10.1016/j.jconrel.2014.03.021

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24300170, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25882011
  • [Journal Article] Three-layered polyplex micelle as a multifunctional nanocarrier platform for light-induced systemic gene transfer2014

    • Author(s)
      T. Nomoto, S. Fukushima, M. Kumagai, K. Machitani, Arnida, Y. Matsumoto, M. Oba, K. Miyata, K. Osada, N. Nishiyama, K. Kataoka
    • Journal Title

      Nature Communications

      Volume: 5 Issue: 1 Pages: 3545-3545

    • DOI

      10.1038/ncomms4545

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-11J08266, KAKENHI-PROJECT-13F03042, KAKENHI-PROJECT-14J11005, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-23790043, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25670010
  • [Journal Article] Modulated protonation of side chain aminoethylene repeats in N-substituted polyaspartamides promotes mRNA transfection2014

    • Author(s)
      H. Uchida, K. Itaka, T. Nomoto, T. ishii, T. Suma, M. Ikegami, K. Miyata, M. Oba, N. Nishiyama, K. Kataoka
    • Journal Title

      J. Am. Chem. Soc.

      Volume: 136 Issue: 35 Pages: 12396-12405

    • DOI

      10.1021/ja506194z

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-24300170, KAKENHI-PROJECT-25000006
  • [Journal Article] Fine-tuning of charge-conversion polymer structure for efficient endosomal escape of siRNA-loaded calcium phosphate hybrid micelles2014

    • Author(s)
      Y. Maeda, F. Pittella, T. Nomoto, H. Takemoto, N. Nishiyama, K. Miyata, K. Kataoka
    • Journal Title

      Macromol. Rapid Commun.

      Volume: 35 Issue: 13 Pages: 1211-1215

    • DOI

      10.1002/marc.201400049

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-25000006
  • [Journal Article] Cyclic RGD-linked polymeric micelles for targeted delivery of platinum anticancer drugs to glioblastoma through the blood-brain tumor barrier2013

    • Author(s)
      Y. Miura, N. Nishiyama, et al.
    • Journal Title

      ACS Nano

      Volume: 7 Issue: 10 Pages: 8583-8592

    • DOI

      10.1021/nn402662d

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-13F03042, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-23790043, KAKENHI-PROJECT-24390340, KAKENHI-PROJECT-24659584, KAKENHI-PROJECT-24689051, KAKENHI-PROJECT-25293273, KAKENHI-PROJECT-25670010, KAKENHI-PROJECT-25750172
  • [Journal Article] Block/homo polyplex micelle-based GM-CSF gene therapy via intraperitoneal administration elicits antitumor immunity against peritoneal dissemination and exhibits safety potentials in mice and cynomolgus monkeys.2013

    • Author(s)
      Ohgidani M, Furugaki K, Shinkai K, Kunisawa Y, Itaka K, Kataoka K, Nakano K.
    • Journal Title

      J Control Release

      Volume: 167 Issue: 3 Pages: 238-247

    • DOI

      10.1016/j.jconrel.2013.02.006

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24300170, KAKENHI-PROJECT-24390303, KAKENHI-PROJECT-24390322
  • [Journal Article] Tethered PEG Crowdedness Determining Shape and Blood Circulation Profile of Polyplex Micelle Gene Carriers2013

    • Author(s)
      Theofilus A. Tockary, Kensuke Osada, Qixian Chen, Kaori Machitani, Anjaneyulu Dirisala, Satoshi Uchida, Takahiro Nomoto, Kazuko Toh, Yu Matsumoto, Keiji Itaka, Koji Nitta, Kuniaki Nagayama, and Kazunori Kataoka
    • Journal Title

      Macromolecules

      Volume: 46 Issue: 16 Pages: 6585-6592

    • DOI

      10.1021/ma401093z

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24300170, KAKENHI-PROJECT-24790530, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25882011
  • [Journal Article] Silica nanogelling of environment-responsive PEGylated polyplexes for enhanced stability and intracellular delivery of siRNA2013

    • Author(s)
      N. Gouda, K. Miyata
    • Journal Title

      Biomaterials

      Volume: 34 Issue: 2 Pages: 562-570

    • DOI

      10.1016/j.biomaterials.2012.09.077

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22700489, KAKENHI-PROJECT-23350049, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-23685037
  • [Journal Article] A synthetic approach toward a self-regulated insulin delivery system2012

    • Author(s)
      A.Matsumoto, T.Ishii, J.Nishida, H.Matsumoto, K.Kataoka, Y.Miyahara
    • Journal Title

      Angew.Chem.Int.Ed.

      Volume: 51 Issue: 9 Pages: 2124-2128

    • DOI

      10.1002/anie.201106252

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23350049
  • [Journal Article] Evaluation of intracellular trafficking and clearance from HeLa cells of doxorubic in-bound block copolymers2012

    • Author(s)
      K.Sakai-Kato, N.Nishiyama, et al.
    • Journal Title

      Int.J.Pharm.

      Volume: 423 Issue: 2 Pages: 401-409

    • DOI

      10.1016/j.ijpharm.2011.12.022

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659299, KAKENHI-PROJECT-23350049, KAKENHI-PROJECT-23390009
  • [Journal Article] Smart multilayered assembly for biocompatible siRNA delivery featuring dissolvable silica, endosome-disrupting polycation, and detachable PEG2012

    • Author(s)
      T. Suma, K. Miyata
    • Journal Title

      ACS Nano

      Volume: 6 Issue: 8 Pages: 6693-6705

    • DOI

      10.1021/nn301164a

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22700489, KAKENHI-PROJECT-23350049, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-24659411, KAKENHI-PROJECT-24700476
  • [Journal Article] Enhanced stability and gene silencing ability of siRNA-loaded polyion complexes formulated from polyaspartamide derivatives with a repetitive array of amino groups in the side chain2012

    • Author(s)
      T.Suma, N.Nishiyama, et al
    • Journal Title

      Biomaterials

      Volume: 33 Issue: 9 Pages: 2770-2779

    • DOI

      10.1016/j.biomaterials.2011.12.022

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-09F09358, KAKENHI-PROJECT-21659299, KAKENHI-PROJECT-22700489, KAKENHI-PROJECT-23350049, KAKENHI-PROJECT-23390009
  • [Journal Article] A phenylboronate-functionalized polyion complex micelle for ATP-triggered release of siRNA2012

    • Author(s)
      M. Naito, K. Miyata
    • Journal Title

      Angew. Chem. Int. Ed

      Volume: 51 Issue: 43 Pages: 10751-10755

    • DOI

      10.1002/anie.201203360

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22700489, KAKENHI-PROJECT-23350049
  • [Journal Article] Micellization of cisplatin (NC-6004) reduces its ototoxicity in guinea pigs2012

    • Author(s)
      M.Baba, N.Nishiyama, et al.
    • Journal Title

      J.Control.Release

      Volume: 157 Issue: 1 Pages: 112-117

    • DOI

      10.1016/j.jconrel.2011.07.026

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659299, KAKENHI-PROJECT-23350049, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-23390393, KAKENHI-PROJECT-23790043, KAKENHI-PROJECT-23791880
  • [Journal Article] Pancreatic cancer therapy by systemic administration of VEGF siRNA contained in calcium phosphate/charge-conversional polymer hybrid nanoparticles2012

    • Author(s)
      F. Pittella, K. Miyata
    • Journal Title

      J. Control.Release

      Volume: 161 Issue: 3 Pages: 868-874

    • DOI

      10.1016/j.jconrel.2012.05.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22700489, KAKENHI-PROJECT-22890196, KAKENHI-PROJECT-23350049, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-24659411
  • [Journal Article] Effective transgene expression without toxicity by intraperitoneal administration of PEGdetachable polyplex micelles in mice with peritoneal dissemination2012

    • Author(s)
      Kumagai 1VI, Shimoda S, Wakabayashi R, Kunisawa Y, Ishii T, Osada 1 Itaka K, Nishiyama N, Kataoka K and Nakano K
    • Journal Title

      J Control Release

      Volume: (in press, 2012)

    • Data Source
      KAKENHI-PROJECT-21390374
  • [Journal Article] Targeted polymeric micelles for siRNA treatment of experimental cancer by intravenous injection2012

    • Author(s)
      R. J. Christie, Y. Matsumoto, K. Miyata, T. Nomoto, S. Fukushima, K. Osada, J. Halnaut, F. Pittella, H. -J. Kim, N. Nishiyama, K. Kataoka
    • Journal Title

      ACS Nano

      Volume: 6(6) Issue: 6 Pages: 5174-5189

    • DOI

      10.1021/nn300942b

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J08266, KAKENHI-PROJECT-22700489, KAKENHI-PROJECT-22750098, KAKENHI-PROJECT-23350049, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-23790043
  • [Journal Article] Engineering fibrotic tissue in pancreatic cancer : a novel three-dimensional model to investigate nanoparticle delivery2012

    • Author(s)
      Hitomi Hosoya, Koji Kadowaki, Michiya Matsusaki, Horacio Cabral, Hiroshi Nishihara, Hideaki Ijichi, Kazuhiko Koike, Kazunori Kataoka, Kohei Miyazono, Mitsuru Akashi, Mitsunobu R.Kano
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 419 Issue: 1 Pages: 32-37

    • DOI

      10.1016/j.bbrc.2012.01.117

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-10J05667, KAKENHI-PLANNED-22112002, KAKENHI-PROJECT-23350049
  • [Journal Article] Enhanced gene expression promoted by the quantized folding of pdna within polyplex micelles2012

    • Author(s)
      K. Osada, T. Shiotani, T. A. Tockary, D. Kobayashi, H. Oshima, S. Ikeda, R. J. Christie, K. Itaka, K. Kataoka
    • Journal Title

      Biomaterials

      Volume: 33 Issue: 1 Pages: 325-332

    • DOI

      10.1016/j.biomaterials.2011.09.046

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22750098, KAKENHI-PROJECT-23350049
  • [Journal Article] Homo-catiomer integration into PEGylated polyplex micelle from block-catiomer for systemic antiangiogenic gene therapy for fibrotic pancreatic tumors2012

    • Author(s)
      Q.Chen, K.Osada, T.Ishii, M.Oba, S.Uchida, T.A.Tockary, T.Endo, Z.Ge, H.Kinoh, M.R.Kano, K.Itaka, K.Kataoka
    • Journal Title

      Biomaterials

      Volume: (in press) Issue: 18 Pages: 4722-4730

    • DOI

      10.1016/j.biomaterials.2012.03.017

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-10F00337, KAKENHI-PROJECT-22750098, KAKENHI-PROJECT-23350049, KAKENHI-PROJECT-23790433
  • [Journal Article] Impact of polyplex micelles installed with cyclic RGD peptide as ligand on gene delivery to vascular lesions2012

    • Author(s)
      Kagaya H, Koyama H, Miyata T
    • Journal Title

      Gene Therapy

      Volume: 19 Issue: 1 Pages: 61-69

    • DOI

      10.1038/gt.2011.74

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390244, KAKENHI-PROJECT-22390245, KAKENHI-PROJECT-22800013, KAKENHI-PROJECT-23350049
  • [Journal Article] PEGylated polyplex with optimized PEG shielding enhances gene introduction in lungs by minimizing inflammatory responses2012

    • Author(s)
      Uchida S
    • Journal Title

      Mol Ther

      Volume: 20(6) Issue: 6 Pages: 1196-1203

    • DOI

      10.1038/mt.2012.20

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591004, KAKENHI-PROJECT-22750098, KAKENHI-PROJECT-23350049
  • [Journal Article] Dendrimer phthalocyanine- encapsulated polymeric micelle-mediated photochemical internalization extends the efficacy of photodynamic therapy and overcome the drug-resistance in vivo2011

    • Author(s)
      H.-L.Lu, W.-J.Syu, N.Nishiyama, K.Kataoka, P.-S.Lai
    • Journal Title

      J.Control.Release

      Volume: 155 Issue: 3 Pages: 458-464

    • DOI

      10.1016/j.jconrel.2011.06.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23350049
  • [Journal Article] Disulfide crosslinked polyion complex micelles encapsulating dendrimer phthalocyanine directed to improved efficiency of photodynamic therapy2011

    • Author(s)
      S.Herlambang, N.Nishiyama, et al.
    • Journal Title

      J.Control.Release

      Volume: 155 Issue: 3 Pages: 449-457

    • DOI

      10.1016/j.jconrel.2011.06.019

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659299, KAKENHI-PROJECT-23350049, KAKENHI-PROJECT-23390009
  • [Journal Article] Polyplex micelles prepared from omega-cholesteryl PEG-polycation block copolymers for systemic gene delivery2011

    • Author(s)
      K.Oba, K.Kataoka, et al
    • Journal Title

      Biomaterials Vol.32

      Pages: 652-663

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] Antiangiogenic gene therapy of experimental plasmid DNA carried by RGD-modified crosslinked polyplex micelles2011

    • Author(s)
      Y.Vachutinsky, K.Kataoka, et al
    • Journal Title

      J.Control.Release Vol.149

      Pages: 51-57

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] In situ quantitative monitoring of polyplexes and polyplex micelles in the blood circulation using intravital real-time confocal laser scanning o microscopy2011

    • Author(s)
      T.Nomoto, K.Kataoka, et al.
    • Journal Title

      J.Control.Release

      Volume: (印刷中)掲載確定

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21655039
  • [Journal Article] Improving drug potency and efficacy by nanocarrier-mediated subcellular targeting2011

    • Author(s)
      M.Murakami, K.Kataoka, et al.
    • Journal Title

      Sci.Transl.Med.

      Volume: 3

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] Size-controlled long-circulating PICsome as ruler to measure critical cut-off disposition size into normal and tumor tissues2011

    • Author(s)
      Yasutaka Anraku, Akihiro Kishimura, Atsushi Kobayashi, Makoto Oba, Kazunori Kataoka
    • Journal Title

      Chemical Communications

      Volume: 47 Issue: 21 Pages: 6054-6056

    • DOI

      10.1039/c1cc11465d

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-23106705, KAKENHI-PROJECT-23350049, KAKENHI-PROJECT-23685037
  • [Journal Article] Antiangiogenic gene therapy of experimental pancreatic tumor by sFlt-1 plasmid DNA carried by RGD-modified crosslinked polyplex micelles.2011

    • Author(s)
      Y.Vachutinsky, K.Kataoka, et al.
    • Journal Title

      J.Control. Release

      Volume: 149 Pages: 51-57

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] Improving drug potency and efficacy by nanocarrier-mediated subcellular targeting2011

    • Author(s)
      M.Murakami, K.Kataoka, et al.
    • Journal Title

      Sci.Transl.Med.

      Volume: 3

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21655039
  • [Journal Article] Effect of polymer structure on micelles formed between siRNA and cationic block copolymer Comprising thiols and amidines2011

    • Author(s)
      R. J. Christie, K. Miyata, Y. Matsumoto, T. Nomoto, D. Menasco, T.-C. Lai, M. Pennisi, K. Osada, S. Fukushima, N. Nishiyama, Y. Yamasaki, K. Kataoka
    • Journal Title

      Biomacromolecules

      Volume: 12(9) Issue: 9 Pages: 3174-3185

    • DOI

      10.1021/bm2006714

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659299, KAKENHI-PROJECT-22700489, KAKENHI-PROJECT-22750098, KAKENHI-PROJECT-23350049, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-23790043
  • [Journal Article] Pluronic-based cationic block copolymer for forming pDNA polyplexes with enhanced cellular uptake and improved transfection efficiency2011

    • Author(s)
      T.-C.Lai, K.Kataoka, G.S.Kwon
    • Journal Title

      Biomaterials

      Volume: 32 Issue: 20 Pages: 4594-4603

    • DOI

      10.1016/j.biomaterials.2011.02.065

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23350049
  • [Journal Article] Effect of integrin targeting and PEG shielding on polyplex micelle internalization studied by live-cell imaging2011

    • Author(s)
      F.M.Konig, Y.Vachutinsky, M.Oba, K.Miyata, N.Nishiyama, K.Kataoka, C.Brauchle, N.Ruthardt
    • Journal Title

      Journal of Controlled Release

      Volume: 151(2) Issue: 3 Pages: 104-109

    • DOI

      10.1016/j.jconrel.2011.08.003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20689024, KAKENHI-PROJECT-21659299, KAKENHI-PROJECT-23350049, KAKENHI-PROJECT-23390009
  • [Journal Article] Antiangiogenic gene therapy of experimental pancreatic tumor by sFIt-Iplasmid DNA carried by RGD-modified crosslinked polyplex micelles2011

    • Author(s)
      Y.Vachutinsky, K.Kataoka, et al.
    • Journal Title

      J.Control.Release

      Volume: 149 Pages: 51-57

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] Odd-even effect of repeating aminoethylene units in the side chain of N-substituted polyaspartamides on gene transfection profiles2011

    • Author(s)
      H.Uchida, N.Nishiyama, et al
    • Journal Title

      J.Am.Chem.Soc.

      Volume: 133 Issue: 39 Pages: 15524-15532

    • DOI

      10.1021/ja204466y

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-09F09358, KAKENHI-PROJECT-21659299, KAKENHI-PROJECT-22700489, KAKENHI-PROJECT-23350049, KAKENHI-PROJECT-23390009
  • [Journal Article] Enhanced endosomal escape of siRNA-incorporating hybrid nanoparticles from calcium phosphate and PEG-block charge-conversion polymer for efficient gene knockdown with negligible cytotoxicity2011

    • Author(s)
      F.Pittella, K.Kataoka, et al.
    • Journal Title

      Biomaterials

      Volume: 32 Pages: 3106-3114

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size2011

    • Author(s)
      H. Cabral, Y. Matsumoto, K. Mizuno, Q. Chen, M. Murakami, M. Kimura, Y. Terada, M. R. Kano, K. Miyazono, M. Uesaka, N. Nishiyama, K. Kataoka
    • Journal Title

      Nature Nanotech

      Volume: 6(12) Issue: 12 Pages: 815-823

    • DOI

      10.1038/nnano.2011.166

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659299, KAKENHI-PROJECT-23350049, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-23790043
  • [Journal Article] Combination of Chondroitin Sulfate and Polyplex Micelles from Poly(ethylene glycol)-poly{ N'-[ N-(2-aminoethyl)-2-aminoethyl] aspartamide} Block Copolymer for Prolonged In Vivo Gene Transfection with Reduced Toxicity2011

    • Author(s)
      Uchida S, Itaka K, Chen Q, Osada K, Miyata K, Ishii T, Harada-Shiba M, Kataoka K
    • Journal Title

      J Control Release

      Volume: Vol.2 Pages: 296-302

    • URL

      http://dx.doi.org/10.1016/j.jconrel.2011.04.026

    • Data Source
      KAKENHI-PROJECT-21300177
  • [Journal Article] Combination of Chondroitin Sulfate and Polyplex Micelles from Poly(ethylene glycol)-poly{N'-[N-(2-aminoethyl)-2-aminoethyl]aspartamide} Block Copolymer for Prolonged In Vivo Gene Transfection with Reduced Toxicity2011

    • Author(s)
      Uchida S, Itaka K, Chen Q, Osada K, Miyata K, Ishii T, Harada-Shiba M, Kataoka K
    • Journal Title

      J Control Release

      Volume: 2 Issue: 2 Pages: 296-302

    • DOI

      10.1016/j.jconrel.2011.04.026

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21300177, KAKENHI-PROJECT-22750098, KAKENHI-PROJECT-23350049
  • [Journal Article] Enhanced endosomal escape of siRNA-incorporating hybrid nanoparticles from calcium phosphate and PEG-block charge-conversional polymer for efficient gene knockdown with negligible cytotoxicity2011

    • Author(s)
      F.Pittella, K.Kataoka, et al
    • Journal Title

      Biomaterials Vol.32

      Pages: 3106-3114

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] In situ quantitative monitoring of polyplexes and polyplex Micelles in the blood circulation using intravital real-time confocal laser scanning microscopy2011

    • Author(s)
      T.Nomoto, Y.Matsumoto, K.Miyata, M.Oba, S.Fukushima, N.Nishiyama, T.Yamasoba, K.Kataoka
    • Journal Title

      J.Control.Release

      Volume: 151(2) Issue: 2 Pages: 104-109

    • DOI

      10.1016/j.jconrel.2011.02.011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J08266, KAKENHI-PROJECT-21659299, KAKENHI-PROJECT-23350049, KAKENHI-PROJECT-23390009
  • [Journal Article] Progress and prospects of polyplex nanomicelles for plasmid DNA delivery2011

    • Author(s)
      Itaka K, Kataoka K
    • Journal Title

      Curr Gene Ther

      Volume: Vol.11 Pages: 457-465

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21300177
  • [Journal Article] PEG-detachable cationic polyaspartamide detivatives bearing stearoyl moieties for systemic siRNA delivery toward subcutaneous BxPC3 pancreatic tumor2011

    • Author(s)
      H.-J.Kim, N.Nishiyama, et al
    • Journal Title

      J.Drug Target.

      Volume: 20 Issue: 1 Pages: 33-42

    • DOI

      10.3109/1061186x.2011.632010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-09F09358, KAKENHI-PROJECT-21659299, KAKENHI-PROJECT-22700489, KAKENHI-PROJECT-23350049, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-23790043
  • [Journal Article] Antiangiogenic gene therapy of experimental pancreatic tumor by sFlt-1pl asmid DNA carried by RGD-modified crosslinked polyplex micelles2011

    • Author(s)
      Y.Vachutinsky, K.Kataoka, et al.
    • Journal Title

      J.Control.Release

      Volume: 149 Pages: 51-57

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21655039
  • [Journal Article] OEnhanced endosomal escape of siRNA-incorporating hybrid nanoparticles from calcium phosphate and PEG-block charge-conversion polymer for efficient gene knockdown with negligible cytotoxicity2011

    • Author(s)
      F.Pittella, K.Kataoka, et al.
    • Journal Title

      Biomaterials

      Volume: 32 Pages: 3106-3114

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21655039
  • [Journal Article] Introduction of stearoyl moieties into a biocompatible cationic polyaspar tamide derivative, PAsp(DET), with endosomal escaping function for enhanced siRNA-mediated gene knockdown.2010

    • Author(s)
      H.Kim, K.Kataoka, et al.
    • Journal Title

      J.Control.Release (in press, 掲載確定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21655039
  • [Journal Article] Efficient delivery of bioactive antibodies into the cytoplasm of living cells by charge-conversional polyion complex micelles.2010

    • Author(s)
      Y.Lee, K.Kataoka, et al.
    • Journal Title

      Angew.Chem.Int.Ed. 49

      Pages: 2552-2555

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21655039
  • [Journal Article] Antiangiogenic gene therapy of solid tumor by systemic injection of polyplex micelles loading plasmid DNA encoding soluble Flt-12010

    • Author(s)
      M.Oba, K.Kataoka, et al.
    • Journal Title

      Molecular Pharmaceutics 7

      Pages: 501-509

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] pDNA/poly(L-lysine)polyplexes functionalized with a pH-sensitive charge-conversional poly(aspartamide)derivative for controlled gene delivery to human umbilical vein endothelial cells2010

    • Author(s)
      M.Sanjoh, K.Kataoka, et al.
    • Journal Title

      Macromol.Rapid Commun. ((印刷中)掲載確定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Polyion complex stability and gene silencing efficiency with a siRNA-grafted polymer delivery system2010

    • Author(s)
      H.Takemoto, K.Kataoka, et al.
    • Journal Title

      Biomaterials

      Volume: 31 Pages: 8097-8105

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] Polyplex nanomicelle promotes hydrodynamic gene introduction to skeletal muscle.2010

    • Author(s)
      K.Itaka K.Kataoka, et al.
    • Journal Title

      J.Control. Release

      Volume: 143 Pages: 112-119

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] siRNA-based therapy ameliorates glomerulonephritis.2010

    • Author(s)
      H.Shimizu K.Kataoka, et al.
    • Journal Title

      J.Am.Soc.Nephrol.

      Volume: 21 Pages: 622-633

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] Biodegradable polyamino acid-based polycations as safe and effective gene carrier minimizing cumulative toxicity.2010

    • Author(s)
      K.Itaka K.Kataoka, et al.
    • Journal Title

      Biomaterials 31

      Pages: 3707-3714

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21655039
  • [Journal Article] Antiangiogenic gene therapy of experimental pancreatic tumor by sFlt-1 plasmid DNA carried by RGD-modified crosslinked polyplex micelles.2010

    • Author(s)
      Y.Vachutinsky, K.Kataoka, et al.
    • Journal Title

      J.Control.Release (in press, 掲載確定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21655039
  • [Journal Article] Antiangiogenic gene therapy of solid tumor by systemic injection of polyplex micelles loading plasmid DNA encoding soluble Flt-12010

    • Author(s)
      M.Oba, K.Kataoka, et al
    • Journal Title

      Mol.Pharm. Vol.7

      Pages: 501-509

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] Biodegradable polyamino acid-based polycations as safe and effective gene carrier minimizing cumulative toxicity2010

    • Author(s)
      Itaka K, Ishii T, Hasegawa Y, Kataoka K.
    • Journal Title

      Biomaterials. 31

      Pages: 3707-3714

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21300177
  • [Journal Article] Direct and instantaneous observation of intravenously injected substances using intravital confocal micro-videography2010

    • Author(s)
      Y.Matsumoto, K.Kataoka, et al.
    • Journal Title

      Biomed.Opt.Express

      Volume: 1 Pages: 1209-1216

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21655039
  • [Journal Article] Polyplex nanomicelle promotes hydrodynamic gene introduction to skeletal muscle2010

    • Author(s)
      Itaka K, Osada K, Morii K, Kim P, Yun SH, Kataoka K
    • Journal Title

      J Control Release

      Volume: Vol.143 Pages: 112-119

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21300177
  • [Journal Article] pDNA/poly(L-lysine) polyplexes functionalized with a pH-sensitive charge-conversional poly(aspartamide) derivative for controlled gene delivery to human umbilical vein endothelial cells2010

    • Author(s)
      M.Sanjoh, K.Kataoka, et al.
    • Journal Title

      Macromol. Rapid Commun.

      Volume: 31 Pages: 1181-1186

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] Efficient delivery of bioactive antibodies into the cytoplasm of living cells by charge-conversional polyion complex micelles2010

    • Author(s)
      Y.Lee, K.Kataoka, et al.
    • Journal Title

      Angew.Chem.Int.Ed. 49

      Pages: 2552-2555

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Quantized folding of plasmid DNA condensed with block catiomer into characteristic rod structures promoting transgene efficacy2010

    • Author(s)
      K.Osada, K.Kataoka, et al.
    • Journal Title

      J.Am.Chem.Soc.

      Volume: 132 Pages: 12343-12348

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21655039
  • [Journal Article] Polyion complex stability and gene silencing efficiency with a siRNA-grafted polymer delivery system2010

    • Author(s)
      H.Takemoto, K.Kataoka, et al
    • Journal Title

      Biomaterials Vol.31

      Pages: 8097-8105

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] Direct and instantaneous observation of intravenously injected substances using intravital confocal micro-videography2010

    • Author(s)
      Y.Matsumoto, K.Kataoka, et al.
    • Journal Title

      Biomed.Opt.Express

      Volume: 1 Pages: 1209-1216

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] Polyplex nanomicelle promotes hydrodynamic gene introduction to skeletal muscle2010

    • Author(s)
      Itaka K, Osada K, Morii K, Kim P, Yun SH, Kataoka K.
    • Journal Title

      J Control Release. 143

      Pages: 112-119

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21300177
  • [Journal Article] siRNA-based therapy ameliorates glomerulonephritis2010

    • Author(s)
      H.Shimizu, K.Kataoka, et al.
    • Journal Title

      J.Am.Soc.Nephrol. 21

      Pages: 622-633

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Polyion complex stability and gene silencing efficiency with a siRNA-grafted polymer delivery system2010

    • Author(s)
      H.Takemoto, K.Kataoka, et al.
    • Journal Title

      Biomaterials

      Volume: 31 Pages: 8097-8105

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21655039
  • [Journal Article] Antiangiogenic Gene Therapy of Solid Tumor by Systemic Injection of Polyplex Micelles Loading Plasmid DNA Encoding Soluble Flt-12010

    • Author(s)
      Oba M, Vachutinsky Y, Miyata K, Kano MR, Ikeda S, Nishiyama N, Itaka K, Miyazono K, Koyama H, Kataoka K
    • Journal Title

      Mol Pharm

      Volume: Vol.7 Pages: 501-509

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21300177
  • [Journal Article] Polyplex nanomicelle promotes hydrodynamic gene introduction to skeletal muscle2010

    • Author(s)
      K.Itaka, K.Kataoka, et al.
    • Journal Title

      J.Control.Release 143

      Pages: 112-119

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Visible-drug delivery by supra-molecular nanocarriers directing tosingle-platformed diagnosis and therapy of pancreatic tumor model2010

    • Author(s)
      S.Kaida, K.Kataoka, et al.
    • Journal Title

      Cancer Res.

      Volume: 70 Pages: 7031-7041

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21655039
  • [Journal Article] Spontaneous formation of nanosized unilamellar polyion complex vesicles with tunable size and properties2010

    • Author(s)
      Y.Anraku, K.Kataoka, et al.
    • Journal Title

      J.Am.Chem.Soc. 132

      Pages: 1631-1636

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Antiangiogenic gene therapy of solid tumor by systemic injection of polyplex micelles loading plasmid DNA encoding soluble Flt-12010

    • Author(s)
      M.Oba, K.Kataoka, et al.
    • Journal Title

      Molecular Pharmaceutics 7

      Pages: 501-509

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21655039
  • [Journal Article] Antiangiogenic gene therapy of experimental pancreatic tumor by sFlt-1 plasmid DNA carried by RGD-modified crosslinked polyplex micelles2010

    • Author(s)
      Y.Vachutinsky, K.Kataoka, et al.
    • Journal Title

      J.Control.Release ((印刷中)掲載確定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Versatile and selective synthesis of "Click Chemistry" compatible heterobifunctional poly(ethylene glycol)s possessing azide and alkyne functionalities.2010

    • Author(s)
      S.Hiki, K.Kataoka, et al.
    • Journal Title

      Bioconjugate Chem.

      Volume: 21 Pages: 248-254

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] Introduction of stearoyl moieties into a biocompatible cationic polyaspartamide derivative, PAsp (DET), with endosomal escaping function for enhanced siRNA-mediated gene knockdown.2010

    • Author(s)
      H.Kim, K.Kataoka, et al.
    • Journal Title

      J.Control. Release

      Volume: 145 Pages: 141-148

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] Polyplex nanomicelle promotes hydrodynamic gene introduction to skeletal muscle2010

    • Author(s)
      K.Itaka, K.Kataoka, et al
    • Journal Title

      J.Control.Release Vol.143

      Pages: 112-119

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] Biodegradable polyamino acid-based polycations as safe and effective gene carrier minimizing cumulative toxicity2010

    • Author(s)
      K.Itaka, K.Kataoka, et al.
    • Journal Title

      Biomaterials 31

      Pages: 3707-3714

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Versatile and selective synthesis of"Click Chemistry"compatible heterobifunctional poly(ethylene glycol)s possessing azide and alkyne functionalities.2010

    • Author(s)
      S.Hiki, K.Kataoka, et al.
    • Journal Title

      Bioconjugate Chem. 21

      Pages: 248-254

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21655039
  • [Journal Article] Enhanced transfection with silica-coated polyplexes loading plasmid DNA2010

    • Author(s)
      K.Miyata, K.Kataoka, et al
    • Journal Title

      Biomaterials Vol.31

      Pages: 4764-4770

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] Polyplex nanomicelle promotes hydrodynamic gene introduction to skeletal muscle.2010

    • Author(s)
      K.Itaka K.Kataoka, et al.
    • Journal Title

      J.Control.Release 143

      Pages: 112-119

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21655039
  • [Journal Article] siRNA-based therapy ameliorates glomerulonephritis2010

    • Author(s)
      H.Shimizu, K.Kataoka, et al
    • Journal Title

      J.Am.Soc.Nephrol. Vol.21

      Pages: 622-633

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] Biodegradable polyamino acid-based polycations as safe and effective gene carrier minimizing cumulative toxicity2010

    • Author(s)
      Itaka K, Ishii T, Hasegawa Y, Kataoka K
    • Journal Title

      Biomaterials

      Volume: Vol.31 Pages: 3707-3714

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21300177
  • [Journal Article] Polyplex micelles prepared from omega-cholesteryl PEG-polycation block copolymers for systemic gene delivery2010

    • Author(s)
      M.Oba, K.Kataoka, et al.
    • Journal Title

      Biomaterials

      Volume: 32 Pages: 652-663

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21655039
  • [Journal Article] pDNA/poly(L-lysine) polyplexes functionalized with a pH-sensitive charge-conversional poly(aspartamide) derivative for controlled gene delivery to human umbilical vein endothelial cells2010

    • Author(s)
      M.Sanjoh, K.Kataoka, et al
    • Journal Title

      Macromol.Rapid Commun. Vol.31

      Pages: 1181-1186

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] Thermodynamics of DNA condensation induced by poly(ethylene glycol)-block-polylysine through polyion complex micelle formation2010

    • Author(s)
      W.Kim, K.Kataoka, et al
    • Journal Title

      Biomacromolecules Vol.11

      Pages: 1180-1186

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] Enhanced transfection with silica-coated polyplexes loading plasmid DNA.2010

    • Author(s)
      K.Miyata, K.Kataoka, et al.
    • Journal Title

      Biomaterials

      Volume: 31 Pages: 4764-4770

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] In situ quantitative monitoring of polyplexes and polyplex micelles in the blood circulation using intravital real-time confocal laser scanning microscopy2010

    • Author(s)
      T.Nomoto, K.Kataoka, et al.
    • Journal Title

      J.Control.Release

      Volume: in press(印刷中)(掲載確定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] Antiangiogenic gene therapy of solid tumor by systemic injection of polyplex micelles loading plasmid DNA encoding soluble Flt-12010

    • Author(s)
      M.Oba, K.Kataoka, et al.
    • Journal Title

      Molecular Pharmaceutics

      Volume: 7 Pages: 501-509

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] Spontaneous formation of nanosized unilamellar polyion complex vesicles with tunable size and properties.2010

    • Author(s)
      Y.Anraku, K.Kataoka, et al.
    • Journal Title

      J.Am.Chem.Soc.

      Volume: 132 Pages: 1631-1636

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] Enhanced in vivo magnetic resonance imaging of tumors by PEGylated ironoxide-gold core-shell nanoparticles with prolonged blood circulation properties2010

    • Author(s)
      M.Kumagai, K.Kataoka, et al.
    • Journal Title

      Macromol.Rapid Commun.

      Volume: 31 Pages: 1521-1528

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] pDNA/poly(L-lysine)polyplexes functionalized with a pH-sensitive charge-conversional poly(aspartamide)derivative for controlled genedelivery to human umbilical vein endothelial cells2010

    • Author(s)
      M.Sanjoh, K.Kataoka, et al.
    • Journal Title

      Macromol.Rapid Commun. (in press, 掲載確定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21655039
  • [Journal Article] Quantized folding of plasmid DNA condensed with block catiomer into characteristic rod structures promoting transgene efficacy2010

    • Author(s)
      K.Osada, K.Kataoka, et al.
    • Journal Title

      J.Am.Chem.Soc.

      Volume: 132 Pages: 12343-12348

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] siRNA-based therapy ameliorates glomerulonephritis.2010

    • Author(s)
      H.Shimizu K.Kataoka, et al.
    • Journal Title

      J.Am.Soc.Nephrol. 21

      Pages: 622-633

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21655039
  • [Journal Article] Introduction of stearoyl moieties into a biocompatible cationic polyaspartamide derivative, PAsp(DET), with endosomal escaping function for enhanced siRNA-mediated gene knockdown2010

    • Author(s)
      H.-J.Kim, K.Kataoka, et al
    • Journal Title

      J.Control.Release Vol.145

      Pages: 141-148

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] Antiangiogenic Gene Therapy of Solid Tumor by Systemic Injection of Polyplex Micelles Loading Plasmid DNA Encoding Soluble Flt-1.2010

    • Author(s)
      Oba M, Vachutinsky Y, Miyata K, Kano MR, Ikeda S, Nishiyama N, Itaka K, Miyazono K, Koyama H, Kataoka K
    • Journal Title

      Mol Pharm. (掲載確定,印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21300177
  • [Journal Article] Biodegradable polyamino acid-based polycations as safe and effective gene carrier minimising cumulative toxicity2010

    • Author(s)
      K.Itaka, K.Kataoka, et al
    • Journal Title

      Biomaterials Vol.31

      Pages: 3707-3714

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] Spontaneous formation of nanosized unilamellar polyion complex vesicles with tunable size and properties.2010

    • Author(s)
      Y.Anraku, K.Kataoka, et al.
    • Journal Title

      J.Am.Chem.Soc. 132

      Pages: 1631-1636

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21655039
  • [Journal Article] Enhanced transfection with silica-coated polyplexes loading plasmid DNA.2010

    • Author(s)
      K.Miyata, K.Kataoka, et al.
    • Journal Title

      Biomaterials 31

      Pages: 4764-4770

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21655039
  • [Journal Article] Quantized folding of plasmid DNA condensed with block catiomer into characteristic rod structures promoting transgene efficacy2010

    • Author(s)
      K.Osada, K.Kataoka, et al
    • Journal Title

      J.Am.Chem.Soc. Vol.132

      Pages: 12343-12348

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] Versatile and selective synthesis of "Click Chemistry" compatible heterobifunctional polyethylene glycol)s possessing azide and alkyne functionalities2010

    • Author(s)
      S.Hiki, K.Kataoka, et al.
    • Journal Title

      Bioconjugate Chem. 21

      Pages: 248-254

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Efficient delivery of bioactive antibodies into the cytoplasm of living cells by charge-conversional polyion complex micelles.2010

    • Author(s)
      Y.Lee, K.Kataoka, et al.
    • Journal Title

      Angew.Chem.Int.Ed.

      Volume: 49 Pages: 2552-2555

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] Enhanced transfection with silica-coated polyplexes loading plasmid DNA2010

    • Author(s)
      K.Miyata, K.Kataoka, et al.
    • Journal Title

      Biomaterials 31

      Pages: 4764-4770

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Enhanced in vivo magnetic resonance imaging of tumors by PEGylated iron oxide-gold core-shell nanoparticles with prolonged blood circulation properties2010

    • Author(s)
      M.Kumagai, K.Kataoka, et al.
    • Journal Title

      Macromol.Rapid Commun.

      Volume: 31 Pages: 1521-1528

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21655039
  • [Journal Article] Biodegradable polyamino acid-based polycations as safe and effectivegene carrier minimizing cumulative toxicity.2010

    • Author(s)
      K.Itaka K.Kataoka, et al.
    • Journal Title

      Biomaterials

      Volume: 31 Pages: 3707-3714

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] Introduction of stearoyl moieties into a biocompatible cationic polyaspartamide derivative, PAsp(DET), with endosomal escaping function for enhanced siRNA-mediated gene knockdown2010

    • Author(s)
      H.Kim, K.Kataoka, et al.
    • Journal Title

      J.Control.Release ((印刷中)掲載確定)

    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Polyplex micelles prepared from omega-cholesteryl PEG-polycation blockcopolymers for systemic gene delivery2010

    • Author(s)
      M.Oba, K.Kataoka, et al.
    • Journal Title

      Biomaterials

      Volume: 32 Pages: 652-663

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] Visible-drug delivery by supra-molecular nanocarriers directing to single-platformed diagnosis and therapy of pancreatic tumor model2010

    • Author(s)
      S.Kaida, K.Kataoka, et al.
    • Journal Title

      Cancer Res.

      Volume: 70 Pages: 7031-7041

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] Antiangiogenic gene therapy of solid tumor by systemic injection of polyplex micelles loading plasmid DNA encoding soluble Flt-12010

    • Author(s)
      M. Oba, Y. Vachutinsky, K. Miyata, M.R. Kano, S. Ikeda, N. Nishiyama, K. Itaka, K. Miyazono, H. Koyama, K. Kataoka
    • Journal Title

      Mol. Pharm 7(2)

      Pages: 501-509

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] A photo-activated targeting chemotherapy using glutathione sensitive camptothecin-loaded polymeric micelles.2009

    • Author(s)
      H. Cabral, K. Kataoka, et al.
    • Journal Title

      Pharm. Res. 26

      Pages: 82-92

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] Charge-conversional polyionic complex micelles-efficient nanocarriers for protein delivery into cytoplasm.2009

    • Author(s)
      Y.Lee, K.Kataoka, et al.
    • Journal Title

      Angew. Chem.Int.Ed.

      Volume: 48 Pages: 5309-5312

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] Enhanced percolation and gene expression in tumor hypoxia by PEGylated polyplex micelles.2009

    • Author(s)
      M.Han, K.Kataoka, et al.
    • Journal Title

      Mol.Ther.

      Volume: 17 Pages: 1404-1410

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] Environment-responsive block copolymer micelles with a disulfide cross-linked core for enhanced siRNA delivery.2009

    • Author(s)
      S. Matsumoto, K. Kataoka, et al.
    • Journal Title

      Biomacromolecules 10

      Pages: 119-127

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] Intratracheal gene transfer of adrenomedullin using polyplex nanomicelles attenuates monocrotaline-induced pulmonary hypertension in rats2009

    • Author(s)
      M. Harada-Shiba, K. Kataoka, et.al.
    • Journal Title

      Molecular Ther. (印刷中)(掲載確定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Intratracheal gene transfer of adrenomedullin using polyplex nanomicelles attenuates monocrotaline-induced pulmonary hypertension2009

    • Author(s)
      M.Harada-Shiba, K.Kataoka, et al
    • Journal Title

      Mol.Ther. Vol.17

      Pages: 1180-1186

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] Enhanced magnetic resonance imaging of experimental pancreatic tumor in vivo by block-copolymer-coated magnetite nanoparticles combined with TGF-beta inhibitor.2009

    • Author(s)
      M.Kumagai, K.Kataoka, et al.
    • Journal Title

      J.Control.Release 140

      Pages: 306-311

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21655039
  • [Journal Article] Intratracheal gene transfer of adrenomedullin using polyplex nanomicelles attenuates monocrotaline-induced pulmonary hypertension in rats2009

    • Author(s)
      M.Harada-Shiba, K.Kataoka, et al.
    • Journal Title

      Molecular Ther. 17

      Pages: 1180-1186

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Intratracheal gene transfer of adrenomedullin using polyplex nanomicelles attenuates monocrotaline-induced pulmonary hypertension in rats.2009

    • Author(s)
      M.Harada-Shiba, K.Kataoka, et al.
    • Journal Title

      Molecular Ther. 17

      Pages: 1180-1186

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21655039
  • [Journal Article] Enhanced photodynamic cancer treatment by supramolecular nanocarriers charged with dendrimer phthalocyanine2009

    • Author(s)
      N. Nishiyama, K. Kataoka, et.al.
    • Journal Title

      J. Control. Release 133

      Pages: 245-251

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Enhanced magnetic resonance imaging of experimental pancreatic tumor in vivo by block-copolymer-coated magnetite nanoparticles with TGF-beta inhibitor2009

    • Author(s)
      M. Kumagai, M.R. Kano, Y. Morishita, M. Ota, Y. Imai, N. Nishiyama, M. Sekino, S. Ueno, K. Miyazono, K. Kataoka
    • Journal Title

      J. Control. Release 140(3)

      Pages: 306-311

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Enhanced magnetic resonance imaging of experimental pancreatic tumor in vivo by block-copolymer-coated magnetite nanoparticles combined with TGF-beta inhibitor2009

    • Author(s)
      M.Kumagai, K.Kataoka, et al.
    • Journal Title

      J.Control.Release 140

      Pages: 306-311

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Enhanced photodynamic cancer treatment by supramolecular nanocarriers charged with dendrimer phthalocyanine.2009

    • Author(s)
      N. Nishiyama, K. Kataoka, et al. et al.
    • Journal Title

      J. Control. Release 133

      Pages: 245-251

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] Enhanced percolation and gene expression in tumor hypoxia by PEGylated polyplex micelles2009

    • Author(s)
      M.Han, K.Kataoka, et al
    • Journal Title

      Mol.Ther. Vol.17

      Pages: 1404-1410

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] PEGylated calcium phosphate nanocomposites as smart environment-sensitive carriers for siRNA delivery2009

    • Author(s)
      M.Zhang, K.Kataoka, et al
    • Journal Title

      Adv.Mater. Vol.21

      Pages: 3520-3525

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] Charge-conversional polyionic complex micelles-efficient nanocarriers for protein delivery into cytoplasm2009

    • Author(s)
      Y.Lee, K.Kataoka, et al.
    • Journal Title

      Angew.Chem.Int.Ed. 48

      Pages: 5309-5312

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] A photo-activated targeting chemotherapy using glutathione sensitive camptothecin-loaded polymeric micelles2009

    • Author(s)
      H. Cabral, K. Kataoka, et.al.
    • Journal Title

      Pharm. Res. 26

      Pages: 82-92

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Charge-conversional polyionic complex micelles-efficient nanocarriers for protein delivery into cytoplasm.2009

    • Author(s)
      Y.Lee, K.Kataoka, et al.
    • Journal Title

      Angew.Chem.Int.Ed. 48

      Pages: 5309-5312

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21655039
  • [Journal Article] PEGylated calcium phosphate nanocomposites as smart environment-sensitive carriers for siRNA delivery2009

    • Author(s)
      M.Zhang, K.Kataoka, et al.
    • Journal Title

      Adv.Mater. 21

      Pages: 3520-3525

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Intratracheal gene transfer of adrenomedullin using polyplex nanomicelles attenuates monocrotaline-induced pulmonary hypertension in rats.2009

    • Author(s)
      M. Harada-Shiba, K. Kataoka, et al.
    • Journal Title

      Molecular Ther. (印刷中 掲載確定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] PEGylated calcium phosphate nanocomposites as smart environment-sensitive carriers for siRNA delivery2009

    • Author(s)
      M.Zhang, K.Kataoka, et al.
    • Journal Title

      Adv.Mater. 21

      Pages: 3520-3525

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21655039
  • [Journal Article] Enhanced magnetic resonance imaging of experimental pancreatic tumor in vivo by block-copolymer-coated magnetite nanoparticles combined with TGF-beta inhibitor.2009

    • Author(s)
      M.Kumagai, K.Kataoka, et al.
    • Journal Title

      J.Control. Release

      Volume: 140 Pages: 306-311

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] Enhanced percolation and gene expression in tumor hypoxia by PEGylated polyplex micelles2009

    • Author(s)
      M. Han, M. Oba, N. Nishiyama, M.R. Kano, S. Kizaka-Kondoh, K. Kataoka
    • Journal Title

      Mol. Ther. 17(8)

      Pages: 1404-1410

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] 3D spheroid culture system on micropatterned substrates for improved differentiation efficiency of multipotent mesenchymal stem cells2009

    • Author(s)
      W.Wang, K.Kataoka, et al
    • Journal Title

      Biomaterials Vol.30

      Pages: 2705-2715

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] PEGylated calcium phosphate nanocomposites as smart environment-sensitive carriers for siRNA delivery2009

    • Author(s)
      M.Zhang, K.Kataoka, et al.
    • Journal Title

      Adv.Mater.

      Volume: 21 Pages: 3520-3525

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] Charge-conversional polyionic complex micelles-efficient nanocarriers for protein delivery into cytoplasm.2009

    • Author(s)
      Y. Lee, K. Kataoka, et al.
    • Journal Title

      Angew. Chem. Int. Ed. (印刷中 掲載確定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article]2009

    • Author(s)
      S.Matsumoto, K.Kataoka, et al
    • Journal Title

      Biomacromolecules Vol.10

      Pages: 119-127

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] Intratracheal gene transfer of adrenomedullin using polyplex nanomicelles attenuates monocrotaline-induced pulmonary hypertension in rats.2009

    • Author(s)
      M.Harada-Shiba, K.Kataoka, et al.
    • Journal Title

      Molecular Ther.

      Volume: 17 Pages: 1180-1186

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] Charge-conversional polyionic complex micelles-efficient nanocarriers for protein delivery into cytoplasm2009

    • Author(s)
      Y. Lee, K. Kataoka, et.al.
    • Journal Title

      Angew. Chem. Int. Ed. (印刷中)(掲載確定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Environment-responsive block copolymer micelles with a disulfidecross-linked core for enhanced siRNA delivery2009

    • Author(s)
      S. Matsumoto, K. Kataoka, et.al.
    • Journal Title

      Biomacromolecules 10

      Pages: 119-127

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Enhanced percolation and gene expression in tumor hypoxia by PEGylated polyplex micelles.2009

    • Author(s)
      M.Han, K.Kataoka, et al.
    • Journal Title

      Mol.Ther. 17

      Pages: 1404-1410

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21655039
  • [Journal Article] Enhanced percolation and gene expression in tumor hypoxia by PEGylated polyplex micelles2009

    • Author(s)
      M.Han, K.Kataoka, et al.
    • Journal Title

      Mol.Ther. 17

      Pages: 1404-1410

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] PEG-detachable polyplex micelles based on disulfide-linked block catiomers as bioresponsive nonviral gene vectors2008

    • Author(s)
      S. Takae, K. Miyata, M. Oba, T. Ishii, N. Nishiyama, K. Itaka, Y. Yamasaki, H. Koyama, K. Kataoka
    • Journal Title

      J. Am. Chem. Soc. 130(18)

      Pages: 6001-6009

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Enhancement of Angiogenesis through Stabilization of Hypoxia Inducible Factor-1 by Silehcing Proly1 Hydroxylase Domain 2 Gene2008

    • Author(s)
      S, Wu, K. Kataoka, et. al.
    • Journal Title

      Mol. Ther. (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Charge-conversional ternary polyplex with endosome disruption moiety: a new paradaigm for the efficient and safe gene delivery.2008

    • Author(s)
      Y. Lee, K. Kataoka, et al.
    • Journal Title

      Angew. Chem. Int. Ed. 47

      Pages: 5163-5166

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] PEG-detachable polyplex micelles based on disulfide-linked block catiomers as bioresponsive non-viral gene vectors.2008

    • Author(s)
      S. Takae, K. Kataoka et al.
    • Journal Title

      J. Am. Chem. Soc. 130

      Pages: 6001-6009

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Polyplexes from poly (aspartamide) bearing 1,2-diaminoethane side chains induce pH-selective, endosomal membrane destabilization with amplifiedt ransfection and negligible cytotoxicity2008

    • Author(s)
      Miyata, K. Kataoka, et.al.
    • Journal Title

      J. Am. Chem. Soc. 130

      Pages: 16287-16294

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] PEG-detachable polyplex micelles based on disulfide-linked block catiomers as bioresponsive non-viral gene vectors.2008

    • Author(s)
      S.Takae, K. Kataoka, et. al.
    • Journal Title

      J.Am. Chem. Soc. (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Dendrimer generation effects on photodynamic efficacy of dendrimer porphyrins and dendrimer-loaded supramolecular nanocarriers2008

    • Author(s)
      Y. Li, K. Kataoka et al.
    • Journal Title

      Chem. Mater. 19

      Pages: 5557-5562

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Polyplex micelles with cyclic RGD peptide ligands and disulfide cross-links directing to the enhanced transfection via controlled intracellular trafficking2008

    • Author(s)
      M. Oba, K. Aoyagi, K. Miyata, Y. Matsumoto, K. Itaka, N. Nishiyama, Y. Yamasaki, H. Koyama, K. Kataoka
    • Journal Title

      Mol. Pharm. 5(6)

      Pages: 1080-1092

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Polyplex micelles from triblock copolymers composed of tandemly aligned segments with biocompatible, endosomal escaping, and DNA-condensing functions for systemic gene delivery to pancreatic tumor2008

    • Author(s)
      K. Miyata, M. Oba, M.R. Kano, S. Fukushima, Y. Vachutinsky, M. Han, H. Koyama, K. Miyazono, N. Nishiyama, K. Kataoka
    • Journal Title

      Pharm. Res. 25(12)

      Pages: 2924-2936

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Polyplex micelles from triblock copolymers composed of tandemly aligned segments with biocompatible, endosomal escaping, and DNA-condensing functions for systemic gene delivery to pancreatic tumor tissue2008

    • Author(s)
      K. Miyata, K. Kataoka, et.al.
    • Journal Title

      Pharm. Res. 25

      Pages: 2924-2936

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Enhancement of angiogenesis through stabilization of hypoxia inducible factor-1 by silencing prolyl hydroxylase domain 2 gene2008

    • Author(s)
      S. Wu, K. Kataoka, et.al.
    • Journal Title

      Molecular Ther. 16

      Pages: 1227-1234

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Photodynamic therapy for corneal neovascularization using polymeric micelles encapsulating dendrimer porphyrins2008

    • Author(s)
      K. Sugisaki, K. Kataoka, et. al.
    • Journal Title

      Invest. Ophth. Vis. Sci. 49

      Pages: 894-899

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Polyplex micelles with cyclic RGD peptide ligands and disulfide crosslinks directing to the enhanced transfection via controlled intracellular trafficking2008

    • Author(s)
      M. Oba, K. Kataoka, et.al.
    • Journal Title

      Mol. Pharm. 5

      Pages: 1080-1092

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Selection between block-and homo-polyelectrolytes through polyion complex formation in aqueous medium2008

    • Author(s)
      A. Harada, K. Kataoka
    • Journal Title

      Soft Matter 4(1)

      Pages: 162-167

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Polyplexes from poly(aspartamide) bearing 1, 2-diaminoethane side chains induce pH-selective, endosomal membrane destabilization with amplified transfection and negligible cytotoxicity2008

    • Author(s)
      K. Miyata, M. Oba, M. Nakanishi, S. Fukushima, Y. Yamasaki, H. Koyama, N. Nishiyama, K. Kataoka
    • Journal Title

      J. Am. Chem. Soc. 130(48)

      Pages: 16287-16294

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Polyplexes from poly(aspartamide) bearing 1,2-diaminoethane side chains induce pH-selective, endosomal membrane destabilization with amplified transfection and negligible cytotoxicity.2008

    • Author(s)
      K. Miyata, K. Kataoka. et al.
    • Journal Title

      J. Am. Chem. Soc. 130

      Pages: 16287-16294

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] PEG-detachable polyplex micelles based on disulfide-linked block catiomers as bioresponsive non-viral gene vectors.2008

    • Author(s)
      S. Takae K. Kataoka, et al.
    • Journal Title

      J. Am. Chem. Soc. 130

      Pages: 6001-6009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] Polyplex micelles from triblock copolymers composed of tandemly aligned segments with biocompatible, endosomal escaping, and DNA-condensing functions for systemic gene delivery to pancreatic tumor tissue.2008

    • Author(s)
      K. Miyata,K. Kataoka, et al.
    • Journal Title

      Pharm. Res. 25

      Pages: 2924-2936

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] Polyplex micelles with cyclic RGD peptide ligands and disulfide crossl inks directing to the enhanced transfection via controlled intracellular trafficking.2008

    • Author(s)
      M. Oba, K. Kataoka. et al.
    • Journal Title

      Mol. Pharm. 5

      Pages: 1080-1092

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] PEG-detachable polyplex micelles based on disulfide-linked block catiomers as bioresponsive non-viral gene vectors2008

    • Author(s)
      S. Takae K. Kataoka, et.al.
    • Journal Title

      J. Am. Chem. Soc. 130

      Pages: 6001-6009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Selection between block-and homo-polyelectrolytes through polyion complex formation in aqueous medium2008

    • Author(s)
      A. Harada, K. Kataoka
    • Journal Title

      Soft Matter 4

      Pages: 162-167

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Enhancement of angiogenesis through stabilization of hypoxia inducible factor-1 by silencing prolyl hydroxylase domain 2 gene.2008

    • Author(s)
      S. Wu, K. Kataoka, et al.
    • Journal Title

      Molecular Ther. 16

      Pages: 1227-1234

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240046
  • [Journal Article] Charge-conversional ternary polyplex with endosome disruption moiety : a new paradaigm for the efficient and safe gene delivery2008

    • Author(s)
      Y. Lee, K. Kataoka, et.al.
    • Journal Title

      Angew. Chem., Int. Ed. 47

      Pages: 5163-5166

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Iron hydroxide nanoparticles coated with poly (ethylene glycol)-poly (asparticacid) block copolymer as novel magnetic resonance contrast agents for in vivo cancer imagmg.2007

    • Author(s)
      M. Kumagai, K. Kataoka et al.
    • Journal Title

      Colloids Surf., B Biointerfaces 56

      Pages: 174-181

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Biocompatible micellar nanovectors achieve efficient gene transfer to vascular lesions without cytotoxicity and thrombus formation2007

    • Author(s)
      D. Akagi, M. Oba, H. Koyama, N. Nishiyama, S. Fukushima, T. Miyata, H. Nagawa, K. Kataoka
    • Journal Title

      Gene Ther. 14(13)

      Pages: 1029-1038

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] pH-Responsive Multi-PEGylated Dual Cationic Nanoparticles Enable Charge Modulations for Safe Gene Delivery.2007

    • Author(s)
      M.P. Xiong, K. Kataoka, et. al.
    • Journal Title

      Chem MedChem 2

      Pages: 1321-1327

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Encapsulation of myoglobin in PEGylated polyion complex vesicles made from a pair of oppositely charged block ionomers : a physiologically available oxygen carrier2007

    • Author(s)
      A. Kishimura, A. Koide, K. Osada, Y. Yamasaki, K. Kataoka
    • Journal Title

      Angew. Chem. Int. Ed. 46(32)

      Pages: 6085-6088

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Enhanced growth inhibition of hepatic multicellular tumor spheroids by lactosylated poly (ethylene glycol)-siRNA conjugate formulated in PEGylated polyplexes2007

    • Author(s)
      M. Oishi, Y. Nagasaki, N. Nishiyama, K. Itaka, M. Takagi, A. Shimamoto, Y. Furuichi, K. Kataoka
    • Journal Title

      ChemMedChem 2(9)

      Pages: 1290-1297

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Biocompatible micellar nanovectors achieve efficient gene transfer to vascular lesions without cytotoxicity and thrombus formation.2007

    • Author(s)
      D. Akagi, K. Kataoka, et. al.
    • Journal Title

      Gene Ther. 14

      Pages: 1029-1038

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] A facile synthesis of azido-terminated heterobifunctional poly (ethylene glycol) s for "Click" conjugation2007

    • Author(s)
      S. Hiki, K. Kataoka
    • Journal Title

      Bioconjugate. Chem. 18(6)

      Pages: 2191-2196

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Cyclic RGD peptide-conjugated polyplex micelles as a targetable gene delivery system directed to cells possessing alphavbeta3 and alphavbeta5 integrins.2007

    • Author(s)
      M. Oba, K. K. Kataoka, et. al.
    • Journal Title

      Bioconjugate Chem. 18

      Pages: 1415-1423

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Encapsulation of myoglobin in PEGylated polyion complex vesicles made from a pair of oppositely charged block ionomers: a phy2007

    • Author(s)
      A. Kishimura, K. Kataoka et al.
    • Journal Title

      Angew. Chem. Int. Ed. 46

      Pages: 6085-6088

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Gene delivery with biocompatible cationic polymer: Pharmacogenomic analysis on cell bioactivity.2007

    • Author(s)
      K. Masago, K. Kataoka, et. al.
    • Journal Title

      Biomaterials 28

      Pages: 5169-5175

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Preparation of naphthalocyanine dendrimer loaded polyion complex micelle for photodynamic therapy.2007

    • Author(s)
      W. -D. Jang, K. Kataoka, et. al.
    • Journal Title

      Key Eng. Mater. 342-343

      Pages: 465-468

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] PEG-based block catiomers possessing DNA anchoring and endosomal escaping functions to form polyplex micelles with improved stability and high transfection efficacy2007

    • Author(s)
      K. Miyata, S. Fukushima, N. Nishiyama, Y. Yamasaki, K. Kataoka
    • Journal Title

      J. Control. Release 122(3)

      Pages: 252-260

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] In Vivo Antitumor Activity of the Folate-Conjugated pH-Sensitive Polymeric Micelle Selectively Releasing Adriamycin in the Intracellular Acidic Compartments.2007

    • Author(s)
      Y. Bae, K. Kataoka, et. al.
    • Journal Title

      J.Control. Release 18

      Pages: 1131-1139

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Optimization of (1,2-diamino-cyclohexane) platinum (II)-loaded polymeric micelles directed to improved tumor targeting and enhanced antitumor activity.2007

    • Author(s)
      H. Cabral, N. Nishiyama, K. Kataoka
    • Journal Title

      J. Control. Release 121

      Pages: 146-155

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591578
  • [Journal Article] Bone regeneration by regulated in vivo gene transfer using biocompatible polyplex nanomicelles2007

    • Author(s)
      Keiji Itraka, Kazunori Kataoka, et al.
    • Journal Title

      Molecular Therapy (in press)

    • Data Source
      KAKENHI-PROJECT-17390412
  • [Journal Article] Bone regeneration by regulated in vivo gene transfer using biocompatible polyplex nanomice2007

    • Author(s)
      Itaka K, Kataoka K, et. al.
    • Journal Title

      Mol Ther 15

      Pages: 1655-1662

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390412
  • [Journal Article] Light-induced gene transfer from packaged DNA enveloped in a dendrimeric photosensitizer.2007

    • Author(s)
      N. Nishiyama, K. Kataoka et al.
    • Journal Title

      Nature Mater. 4

      Pages: 934-941

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Semipermeable polymer vesicle (PICsome) self-assembled in aqueous medium from a pair of oppositely charged block copolymers: physiologically stable micro-/nanocontainers of water-soluble macromolecules.2007

    • Author(s)
      A. Koide, K. Kataoka et al.
    • Journal Title

      J. Am. Chem. Soc. 128

      Pages: 5988-5989

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Enhanced Growth Inhibition of Hepatic Multicellular Tumor Spheroids by Lactosylated Poly(ethylene glycol)-siRNA Conjugate Formulated in PEGylated Polyplexes.2007

    • Author(s)
      M. Oishi, K. Kataoka, et. al.
    • Journal Title

      ChemMedChem 2

      Pages: 1290-1297

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Enhanced growth inhibition of hepatic multicellular tumor spheroids by lactosylated poly (ethylene glycol)-siRNA conjugate formulated in PEGylated polyplexes.2007

    • Author(s)
      M. Oishi, K. Kataoka et al.
    • Journal Title

      ChemMedChem 2

      Pages: 1290-1297

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumors by inhibition of TGF-betasignaling.2007

    • Author(s)
      M. R. Kano, K. Kataoka et al.
    • Journal Title

      Proc. Natl. Acad. Sci. USA. 104

      Pages: 3460-3465

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Cyclic RGD peptide-conjugated polyplex micelles as a targetable gene delivery system directed to cells possessing alphavbeta3 and alphavbeta5 integrins.2007

    • Author(s)
      M. Oba, K.K. Kataoka et al.
    • Journal Title

      Bioconjugate Chem. 18

      Pages: 1415-1423

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Ih Vivo Antitumor Activity of the Folate -Conjugated pH-Sensitive Polymeric Micelle Selectively Releasing Adriamycin in the Intracellular Acidic Compartments.2007

    • Author(s)
      Y. Bae, K. Kataoka et al.
    • Journal Title

      J. Control. Release 18

      Pages: 1131-1139

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] In vivo antitumor activity of the folate-conjugated pH-sensitive polymeric micelle selectively releasing adriamycin in the intracellular acidic compartments2007

    • Author(s)
      Y. Bae, N. Nishiyama, K. Kataoka
    • Journal Title

      Bioconjugate Chem. 18(4)

      Pages: 1131-1139

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] PEG-based block catiomers possessing DNA anchoring and endosomal escaping functions to form polyplex micelles with improved stability and high transfection effocacy.2007

    • Author(s)
      K. Miyata, K. Kataoka, et. al.
    • Journal Title

      J.Control. Release 122

      Pages: 252-260

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Optimization of (1,2-diamino-cyclohexane) platinum(II)-loaded polymeric micelles directedto improved tumor targeting and enhanced antitumor activity.2007

    • Author(s)
      H. Cabral, N. Nishiyama, K. Kataoka
    • Journal Title

      J. Control. Release 121

      Pages: 146-155

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591578
  • [Journal Article] Kataoka, Supramolecular nanocarriers integrated with dendrimers encapsulating photosensitizers for effective photodynamic therapy and photochemical gene delivery.2007

    • Author(s)
      N. Nishiyama, K. Kataoka, et. al.
    • Journal Title

      New J. Chem. 31

      Pages: 1074-1082

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumors by inhibition of TGF-beta signaling2007

    • Author(s)
      M. R. Kano, Y. Bae, C. Iwata, Y. Morishita, M. Yashiro, M. Oka, T. Fujii, A. Komuro, K. Kiyono, M. Kamiishi, K. Hirakawa, Y. Ouchi, N. Nishiyama, K. Kataoka, K. Miyazono
    • Journal Title

      Proc. Natl. Acad. Sci. USA. 104(9)

      Pages: 3460-3465

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Cyclic RGD peptide-conjugated polyplex micelles as a targetable gene delivery system directed to cells possessing alphavbeta3 and alphavbeta5 integrins2007

    • Author(s)
      M. Oba, K. Kataoka, et. al.
    • Journal Title

      Bioconjugate Chem 18

      Pages: 1415-1423

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Dendrimer generation effects on photodynamic efficacy of dendrimer porphyrins and dendrimer-loaded supramolecular nanocarriers2007

    • Author(s)
      Y. Li, W. -D. Jang, N. Nishiyama, A. Kishimura, S. Kawauchi, Y. Morimoto, S. Miake, T. Yamashita, M. Kikuchi, T. Aida, K. Kataoka
    • Journal Title

      Chem. Mater. 19(23)

      Pages: 5557-5562

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Freeze-dried formulations for in vivo gene delivery of PEG ylated polyplex micelles with disulfide crosslinked cores to the liver.2007

    • Author(s)
      K. Miyata, K. Kataoka et al.
    • Journal Title

      J. Control. Release 109

      Pages: 15-23

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Bone regeneration by regulated in vivo gene transfer using biocompatible polyplex nanomicelles2007

    • Author(s)
      K.Itaka, K. Kataoka, et. al.
    • Journal Title

      Mol. Ther. 15

      Pages: 1655-1662

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] A protein nanocarrier from charge-conversion polymer in response to endosomal pH2007

    • Author(s)
      Y. Lee, S. Fukushima, Y. Bae, S. Hiki, T. Ishii, K. Kataoka
    • Journal Title

      J. Am, Chem. Soc 129(17)

      Pages: 5362-5363

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Cyclic RGD peptide-conjugated polyplex micelles as a targetable gene delivery system directed to cells possessing alphavbeta3 and alphavbeta5 integrins2007

    • Author(s)
      M. Oba, S. Fukushima, N. Kanayama, K. Aoyagi, N. Nishiyama, H. Koyama, K. Kataoka
    • Journal Title

      Bioconjugate Chem. 18(5)

      Pages: 1415-1423

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Bone regeneration by regulated in vivo gene transfer using biocompatible polyplex nanomicelles.2007

    • Author(s)
      Itaka K, Kataoka K, et. al.
    • Journal Title

      Mol Ther 15

      Pages: 1655-1662

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390412
  • [Journal Article] Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumors by inhibition of TGF-beta signaling.2007

    • Author(s)
      M. R. Kano, K. Kataoka, et. al.
    • Journal Title

      Proc. Natl. Acad. Sci. USA. 104

      Pages: 3460-3465

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Dendrimer Generation Effects on Photodynamic Efficacy of Dendrimer Porphyrins and Dendrimer-Loaded Supramolecular Nanocarrier2007

    • Author(s)
      Y.Li, K. Kataoka, et. al.
    • Journal Title

      Chem. Mater. 19

      Pages: 5557-5562

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] PEG-based block catiomers possessing DNA anchoring and endosomal escaping functions to form polyplex micelles with improved stability and high transfection efficacy.2007

    • Author(s)
      K. Miyata, K. Kataoka et al.
    • Journal Title

      J. Control. Release 122

      Pages: 252-260

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] In Vivo antitumor activity of the folate-conjugated pH-sensitive polymeric micelle selectively releasing adriamycin in the intracellular acidic compartments.-2007

    • Author(s)
      Bae Y, Nishiyama N, Kataoka K
    • Journal Title

      Bioconjugate Chemistry 18

      Pages: 1131-1139

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591578
  • [Journal Article] Supramolecular assemblies for the cytoplasmic delivery of antisense oligodeoxynucleotide: polyion complex (PIC) micelles based on poly (ethyleneglycol)-SS-oligodeoxynucleotide conjugate.2007

    • Author(s)
      M. Oishi, K. Kataoka et al.
    • Journal Title

      Biomacromolecules 6

      Pages: 2449-2454

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Transfection Study Using Multicellular Tumor Spheroids for Screening Non-viral Polymeric Gene Vectors with Low Cytotoxicity and High Transfection Efficiencies.2007

    • Author(s)
      M. Han, K. Kataoka et al.
    • Journal Title

      Bioconjugate Chem. 121

      Pages: 38-48

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Transfection study using multicellular tumor spheroids for screening non-viral polymeric gene vectors with low cytotoxicity and high transfection efficiencies2007

    • Author(s)
      M. Han, Y. Bae, N. Nishiyama, K. Miyata, M. Oba, K. Kataoka
    • Journal Title

      J. Control. Release 121(1-2)

      Pages: 38-48

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Cisplatin-incorporating polymeric micelles (NC-6004) can reduce nephrotoxicity and neurotoxicity of cisplatin in rats.2007

    • Author(s)
      H. Uchino, K. Kataoka et al.
    • Journal Title

      Br. J. Cancer 93

      Pages: 678-687

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] In Vivo antitumor activity of the folate-conjugated pH-sensitive polymeric micelle selectively releasing adriamycin in the intracellular acidic compartments2007

    • Author(s)
      Bae Y, Nishivama N, Kataoka K
    • Journal Title

      Bioconjugate Chemistry 18

      Pages: 1131-1139

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591578
  • [Journal Article] Preparation and characterzation of polyion complex micelles with a novel thermosrnsitive poly (2-isopropyl-2-oxazoline) shell via the complexation of oppositely charged block ionomers2007

    • Author(s)
      J. -S. Park, Y. Akiyama, Y. Yamasaki, K. Kataoka
    • Journal Title

      Langmuir 23(1)

      Pages: 138-146

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] A facile synthesis of azido-terminated heterobifunctional poly (ethylene glycol) s for "Click" conjugation2007

    • Author(s)
      S. Hiki, K. Kataoka
    • Journal Title

      Bioconjugate. Chem. 18

      Pages: 2191-2196

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Polyion complex micelles for photodynamic therapy: incorporation of dendritic photosensitizer excitable at long wavelength relevant to improved tissue-penetrating property.2007

    • Author(s)
      W.-D. Jang, K. Kataoka et al.
    • Journal Title

      J. Control. Release 113

      Pages: 73-79

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Preparation and characterization of polyion complex micelles with a novel thermosensitive poly (2-isopropyl-2-oxazoline) shell via the complexation of oppositely charged block ionomers.2007

    • Author(s)
      J.-S. Park, K. Kataoka et al.
    • Journal Title

      Langmuir 23

      Pages: 138-146

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] A protein nanocarrier from charge-conversion polymer in response to endosomal pH.2007

    • Author(s)
      Y. Lee, K. Kataoka et al.
    • Journal Title

      J. Am. Chem. Soc. 129

      Pages: 5362-5363

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Comprehensive and accurate control of thermosensitivity of poly (2-alkyl-2-oxazoline) s via well-defined gradient or random copolymerization2007

    • Author(s)
      J. -S. Park, K. Kataoka
    • Journal Title

      Macromolecules 40(10)

      Pages: 3599-3609

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] PEG-based block catiomers possessing DNA anchoring and endosomal escaping functions to form polyplex micelles with improved stability and high transfection efficacy2007

    • Author(s)
      K. Miyata, S. Fukushima, N. Nishiyama, Y. Yamasaki, K. Kataoka
    • Journal Title

      J. Control. Release 122(3)

      Pages: 252-260

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Optimization of (1, 2-diamino-cyclohexane) platinum (II)-loaded polymeric micelles directed to improved tumor targeting and enhanced antitumor activity.2007

    • Author(s)
      H. Cabral, K. Kataoka et al.
    • Journal Title

      J. Control. Release 121

      Pages: 146-155

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] In vivo antitumor activity of the folate-conjugated pH-sensitive polymeric micelle selectively releasing adriamycin in the intracellular acidic compartments2007

    • Author(s)
      Y. Bae, N. Nishiyama, K. Kataoka
    • Journal Title

      Bioconjugate Chem. 18(4)

      Pages: 11311139-11311139

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] PEG-based block catiomers possessing DNA anchoring and endosomal escaping functions to from polyplex micelles with improved stability and high transfection efficacy2007

    • Author(s)
      K. Miyata, K. Kataoka, et. al.
    • Journal Title

      J. Control. Release 122

      Pages: 252-260

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Optimization of (1, 2-diamino- cyclohexane)platinum(II)-loaded polymeric micelles directed to improved tumor targeting and enhanced antitumor activity2007

    • Author(s)
      H. Cabral, N. Nishiyama, K. Kataoka
    • Journal Title

      J. Control. Release 121(3)

      Pages: 146-155

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Preparation and characterization of polyion complex micelles with a novel thermosensitive poly(2-isopropyl-2-oxazoline) shell via the complexation of oppositely charged block ionomers2007

    • Author(s)
      Park, J-S, Kataoka, K et al.
    • Journal Title

      Langmuir 23(1)

      Pages: 138-146

    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Optimization of (1,2-diamino-cyclohexane)platinum(II)-loaded polymeric micelles directed to improved tumor targeting and enhanced antitumor activity2007

    • Author(s)
      H. Cabral, K. Kataoka, et. al.
    • Journal Title

      J. Control. Release 121

      Pages: 146-155

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] A PEG-based biocompatible block catiomer with high buffering capacity for the construction of polyplex micelles showing efficient gene transfer toward primary cells.2007

    • Author(s)
      N.Kanayama, K. Kataoka et a1.
    • Journal Title

      Chem Med Chem 1

      Pages: 439-444

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumors by inhibition of TGF-beta signaling2007

    • Author(s)
      M.R. Kano, Y. Bae, C. Iwata, Y. Morishita, M. Yashiro, M. Oka, T. Fujii, A. Komuro, K. Kiyono, M. Kaminishi, K. Hirakawa, Y. Ouchi, N. Nishiyama, K. Kataoka, K. Miyazono
    • Journal Title

      P. Natl. Acad. Sci. USA. 104(9)

      Pages: 3460-3465

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Comprehensive and accurate control of thermosensitivity of poly(2-alkyl-2-oxazoline)s via well-defined gradient or random copolymerization.2007

    • Author(s)
      J.-S. Park, K. Kataoka et al.
    • Journal Title

      Macromolecules 40

      Pages: 3599-3609

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Study of the quantitative aminolysis reaction of poly(beta-benzy1 L-aspartate)(PBLA)as a platform polymer for functionality matetials2007

    • Author(s)
      K. Nakanishi, K. Kataoka, et. al.
    • Journal Title

      React. Funct. Polym. 67

      Pages: 1361-1372

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Biocompatible micellar nanovectors achieve efficient gene transfer to vascular lesions without cytotoxicity and thrombus formation.2007

    • Author(s)
      D. Akagi, K. Kataoka et al.
    • Journal Title

      Gene Ther. 14

      Pages: 1029-1038

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Optimization of(1, 2-diamino-cyclohexane) platinum(II)- loaded polymeric micelles directed to improved tumor targeting and enhanced antitumor activity2007

    • Author(s)
      Cabral H, Nishivama N, Kataoka K
    • Journal Title

      J. Controlled Release 121

      Pages: 146-155

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591578
  • [Journal Article] A protein nanocarrier from charge-conversion polymer in response to endosomal pH2007

    • Author(s)
      Y.Lee, K. Kataoka, et. al.
    • Journal Title

      J. Am. Chem. Soc. 129

      Pages: 5362-5363

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Nanotechnology-based photodynamic therapy for neovascular disease using a supramolecular nanocarrier loaded with a dendritic photosensitizer.2007

    • Author(s)
      R. Ideta, K. Kataoka et al.
    • Journal Title

      Nano Lett. 5

      Pages: 2426-2431

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Iron hydroxide nanoparticles coated with poly(ethylene glycol)-poly(aspartic acid)block copolymer as novel magnetic resonance contrast agents for in vivo cancer imaging2007

    • Author(s)
      M. Kumagai, K. Kataoka, et. al.
    • Journal Title

      Colloids Surf., B Biointerfaces 56

      Pages: 174-181

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Optimization of (1,2-diamino-cyclohexane) platinum(II)-loaded polymeric micelles directed to improved tumor targeting and enhanced antitumor activity2007

    • Author(s)
      H. Cabral, N. Nishiyama, K. Kataoka
    • Journal Title

      J. Control. Release 121(3)

      Pages: 146-155

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Organic-inorganic hybrid-nanocarrier of siRNA constructing through the self-assembly of calcium phosphate and PEG-based block aniomer.2007

    • Author(s)
      Y. Kakizawa, K. Kataoka et al.
    • Journal Title

      J. Control. Release 111

      Pages: 368-370

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Iron hydroxide nanoparticles coated with poly (ethylene glycol)-poly (aspartic acid) block copolymer as novel magnetic resonance agents for in vivo cancer imaging2007

    • Author(s)
      M. Kumagai, Y. Imai, T. NAkamura, Y. Yamasaki, M. Sekino, S. Ueno, K. Hanaoka, K. Kikuchi, T. Nagano, E. Kaneko, K. Shimokado, K. Kataoka
    • Journal Title

      Colloids Surf., B Biointerfaces 56

      Pages: 174-181

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Bone regeneration by regulated in vivo gene transfer using biocompatible polyplex nanomicelles2007

    • Author(s)
      K. Itaka, S. Ohba, K. Miyata, H. Kawaguchi, K. Nakamura, T. Takato, U. -I. Chung, K. Kataoka
    • Journal Title

      Mol. Ther. 15(9)

      Pages: 1655-1662

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Optimization of(1,2-diamino-cyclohexane)platinum(II)-loaded polymeric micelles directed to improved tumor targeting and enhanced antitumor activity.2007

    • Author(s)
      H. Cabral, K. Kataoka, et. al.
    • Journal Title

      J.Control. Release 121

      Pages: 146-155

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Transfection Study Using Multicellular Tumor Spheroids for Screening Non-viral Polymeric Cene Vectors with Low Cytotoxicity and High Transfection Efficiencies.2007

    • Author(s)
      M. Han, K. Kataoka, et. al.
    • Journal Title

      Bioconjugate Chem. 121

      Pages: 38-48

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Bone regeneration by regulated in vivo gene transfer using biocompatibli polyplex nanomicelles2007

    • Author(s)
      Itaka K, Kataoka K, et. al.
    • Journal Title

      Mol Ther 15(9)

      Pages: 1655-1662

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390412
  • [Journal Article] Bone regeneration by regulated in vivo gene transfer using biocompatible polyplex nanomicelles.2007

    • Author(s)
      K. Itaka, K. Kataoka et al.
    • Journal Title

      Mol. Ther. 15

      Pages: 1655-1662

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Preparation and characterization of polyion complex micelles with a novel thermosensitive poly(2-isopropy1-2-oxazoline) shell via the complexation of oppositely charged block ionomers2007

    • Author(s)
      Park, J-S, Kataoka, K etal.
    • Journal Title

      Langmuir 23(1)

      Pages: 138-146

    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Freeze-dried formulations for in vivo gene delivery of PEGylated polyplex micelle with disulfide crosslinked cores to the liver2006

    • Author(s)
      Miyata, K., Kataoka, K.et al.
    • Journal Title

      Journal of Controlled Release 109(1-3)

      Pages: 15-23

    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Polyion complex micelles for photodynamic therapy : incorporation of dendritic photosensitizer excitable atlong wavelength relevant to improved tissue-penetrating property2006

    • Author(s)
      W. -D. Jang, Y. Nakagishi, N. Nishiyama, S. Kawauchi, Y. Morimoto, M. Kikuchi, K. Kataoka
    • Journal Title

      J. Cotrol. Release 113(1)

      Pages: 73-79

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] pH-responsive three-layered PEGylated polyplex micelle based on a lactosylated ABC triblock copolymer as a targetable and endosome-disruptive nonviral gene vector.2006

    • Author(s)
      Oishi, M, Kataoka, K et al.
    • Journal Title

      Bioconjugate Chemistry 17 (3)

      Pages: 677-688

    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Organic-inorganic hybrid-nanocarrier of siRNA constructing through the self-assembly of calcium phosphate and PEG-based block aniomer.2006

    • Author(s)
      Kakizawa, Y, Kataoka, K et al.
    • Journal Title

      Journal of Controlled Release 111 (3)

      Pages: 368-370

    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Semipermeable polymer vesicle (PICsome) self-assembled in aqueous medium from a pair of oppositely charged block copolymers : physiologically stable micro-/nanocontainers of water-soluble macromolecules.2006

    • Author(s)
      Koide, A, Kataoka, K et al.
    • Journal Title

      Journal of the American Chemical Society 128(18)

      Pages: 5988-5989

    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] PEGylated gene nanocarriers based on block catiomers bearing ethylenediamine repeating units directed to remarkable enhancement of photochemical transfection2006

    • Author(s)
      Arnia, Kataoka, K et al.
    • Journal Title

      Journal of Controlled Release 115(2)

      Pages: 208-215

    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] pH-responsive three-layered PEGylated polyplex micelle based on a lactosylated ABC triblock copolymer as a targetable and endosome-disruptive nonviral gene vector.2006

    • Author(s)
      Oishi, M, Kataoka, K et al.
    • Journal Title

      Bioconjugate Chemistry 17(3)

      Pages: 677-688

    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Precise control of lower critical solution temperature thermosensitive poly (2-isopropyl-2-oxazoline) via gradient copolymerization with 2-ethyl-2-oxazoline as a hydrophilic comonomer2006

    • Author(s)
      J. -S. Park, K. Kataoka
    • Journal Title

      Macromolecules 39(19)

      Pages: 6622-6630

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Nanostructured devices based on block copolymer assemblies for drug delivery : designing structures for enhanced drug function2006

    • Author(s)
      N.Nishiyama, K.Kataoka
    • Journal Title

      Adv.Polym.Sci.(Polymer Therapeutics II) 193

      Pages: 67-101

    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Organic-inorganic hybrid-nanocarrier of siRNA constructing through the self-assembly of calcium phosphate and PEG-based block aniomer2006

    • Author(s)
      Y. Kakizawa, S. Furukawa, A. Ishii, K. Kataoka
    • Journal Title

      J. Comtrol. Release 111(3)

      Pages: 368-370

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] PEGylated gene nanocarriers based on block catiomers bearing ethylenediamine repeating units directed to remarkable enhancement of photochemical transfection2006

    • Author(s)
      Arnida, Kataoka, K et al.
    • Journal Title

      Journal of Controlled Release 115(2)

      Pages: 208-215

    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Organic-inorganic hybrid-nanocarrier of siRNA constructing through the self-assembly of calcium phosphate and PEG-based block aniomer.2006

    • Author(s)
      Kakizawa, Y, Kataoka, K et al.
    • Journal Title

      Journal of Controlled Release 111(3)

      Pages: 368-370

    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Semipermeable polymer vesicle (PlCsome) self-assembled in aqueous medium from a pair of oppositely charged block copolymers : physiologically stable micro-/nanocontainers of water-soluble macromolecules2006

    • Author(s)
      A. Koide, A. Kishimura, K. Osada, W. -D. Jang, Y. Yamasaki, K. Kataoka
    • Journal Title

      J. Am. Chem. Soc. 128(18)

      Pages: 5988-5989

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Precise control of lower critical solution temperature of thermosensitive poly (2-isopropyl-2-oxazoline) via gradient copolymerization with 2-ethyl-2-oxazoline as a hydrophilic comonomer.2006

    • Author(s)
      J.-S. Park, K. Kataoka
    • Journal Title

      Macromolecules 39

      Pages: 6622-6630

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Semipermeable polymer vesicle (PICsome) self-assembled in aqueous medium from a pair of oppositely charged block copolymers : physiologically stable micro-/nanocontainers of water-soluble macromolecules.2006

    • Author(s)
      Koide, A, Kataoka, K et al.
    • Journal Title

      Journal of the American Chemical Society 128 (18)

      Pages: 5988-5989

    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] A PEG-based biocompatible block catiomer with high buffering capacity for the construction of polyplex micelles showing efficient gene transfer toward primary cells2006

    • Author(s)
      N. Kanayama, S. Fukushima, N. Nishiyama, K. Itaka, W. -D. Jang, K. Miyata, Y. Yamasaki, U. -I. Chung, K. Kataoka
    • Journal Title

      ChemMedChem 1(4)

      Pages: 439-444

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Characterization of stable lysozyme-entrapped polyion complex (PIC) micelles with crosslinked core by glutaraldehyde2005

    • Author(s)
      X. Yuan, Y. Yamasaki, A. Harada, K. Kataoka
    • Journal Title

      Polymer 46(18)

      Pages: 7749-7758

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Multifunctional polymeric micelles with folate-mediated cancer cell targeting and pH-triggered drug releasing properties for active intracellular drug delivery2005

    • Author(s)
      Bae, Y., Kataoka, K.et al.
    • Journal Title

      Molecular Biosystems 1(3)

      Pages: 242-250

    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Supramolecular nanocarrier of anionic dendrimer porphyrins with cationic block copolymers modified with poly(ethylene glycol) to enhance intracellular photodynamic efficacy.2005

    • Author(s)
      Jang WD, Nishiyama N, Koyama H, Kataoka K et al.
    • Journal Title

      Angew.Chem.Int.Ed.Engl 44

      Pages: 419-423

    • Data Source
      KAKENHI-PROJECT-15390373
  • [Journal Article] Supramolecular assemblies for the cytoplasmic delivery of antisense oligodeoxynucleotide : polyion complex (PIC) micelles based on poly (ethylene glycol)-SS-oligodeoxynucleotide conjugate2005

    • Author(s)
      M. Oishi, T. Hayama, Y. Akiyama, S. Takae, A. Hara, Y. Yamasaki, F. Nagatsugi, S. Sasaki, Y. Nagasaki, K. Kataoka
    • Journal Title

      Biomacromolecules 6(5)

      Pages: 2449-2454

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Multifunctional polymeric micelles with folate-mediated cancer cell targeting and pH-triggered drug releasing properties for active intracellular drug delivery.2005

    • Author(s)
      Y. Bae, K. Kataoka et al.
    • Journal Title

      Mol. BioSyst. 1

      Pages: 242-250

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Lactosy-lated Poly(ethylene glycol)-siRNA conjugate through acid-labile β-thiopropionate linkage to construct pH-sensitive polyion complex micelles achieving enhanced gene silencing in hepatoma cells2005

    • Author(s)
      M.Oishi, Y.Nagasaki, K.Itaka, N.Nishiyama, K.Kataoka
    • Journal Title

      J.Am.Chem.Soc. 127(6)

      Pages: 1624-1625

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14380391
  • [Journal Article] Smart polyion complex micelles for targeted intracellular delivery of PEGylated antisense oligonucleotide with acid-labile linkage2005

    • Author(s)
      M.Oishi, S.Sasaki, Y.Nagasaki, K.Kataoka
    • Journal Title

      ChemBioChem (印刷中)

    • Data Source
      KAKENHI-PROJECT-14380391
  • [Journal Article] NK105, a paclitaxel-incorporating micellar nanoparticle formulation, can extend in vivo antitumour activity and reduce the neurotoxicity of paclitaxel.2005

    • Author(s)
      T. Hamaguchi, K. Kataoka et al.
    • Journal Title

      Br. J. Cancer 92

      Pages: 1240-1246

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Light-induced gene transfer from packaged DNA enveloped in a dentrimeric photosensitizer2005

    • Author(s)
      Nishiyama N, Koyama H, Kataoka K, et al.
    • Journal Title

      Nature Material 4

      Pages: 934-941

    • Data Source
      KAKENHI-PROJECT-17390345
  • [Journal Article] Multifunctional polymeric micelles with folate-mediated cancer cell targeting and pH-triggered drug releasing properties for active intracellular drug delivery.2005

    • Author(s)
      Y. Bae, W. -D. Jang, N. Nishiyama, S. Fukushima, K. Kataoka
    • Journal Title

      Mol. BioSyst. 1(3)

      Pages: 242-250

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Supramolecular nanocarrier of anionic dendrimer porphyrins with cationic block copolymers modified with poly (ethylene glycol) to enhance ntracellular photodynamic efficacy2005

    • Author(s)
      W. -D. Jang, N. Nishiyama, G. -D. Zhang, A. Harada, D. -L. Jiang, S. Kawauchi, Y. Morimoto, M. Kikuchi, H. Koyama, T. Aida, K. Kataoka, K. Kataoka
    • Journal Title

      Angew. Chem. Int. Ed. 44(3)

      Pages: 419-423

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Characterization of stable lysozyme-entrapped polyion complex (PIC) micelles with crosslinked core by glutaraldehyde.2005

    • Author(s)
      X. Yuan, K. Kataoka et al.
    • Journal Title

      Polymer 46

      Pages: 7749-7758

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] A synthetic block copolymer regulates S1 nuclease fragmentation of supercoiled plasmid DNA.2005

    • Author(s)
      K.Osada, K. Kataoka et al.
    • Journal Title

      Angew. Chem. Int. Ed. 44

      Pages: 3544-3548

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Preparation and biological characterization of polymeric micelle drug carriers with intracellular pH-triggered drug release property: Tumor permeability, controlled subcellular drug distribution, and enhanced in vivo antitumor efficacy.2005

    • Author(s)
      Y. Bae, K. Kataoka et al.
    • Journal Title

      Bioconjugate Chem. 16

      Pages: 122-130

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Supramolecular nanocarrier of anionic dentrimer porphyrins with cationic block copolymers modified with poly(ethylene glycol) to enhance intracellular photodynamic efficacy2005

    • Author(s)
      Jang WD, Nishiyama N, Koyama H, Kataoka K, et al.
    • Journal Title

      Angew.Chem.Int.Ed.Engl 44

      Pages: 419-423

    • Data Source
      KAKENHI-PROJECT-17390345
  • [Journal Article] Preparation and biological properties of dichloro (1,2-diaminocyclohexane) platinum (II) (DACHPt)-loaded polymeric micelles.2005

    • Author(s)
      H. Cabral, K. Kataoka et a1.
    • Journal Title

      J.Control. Release 101

      Pages: 223-232

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Preparation and biological properties of dichloro (1,2-diaminocyclohexane) platinum(II)(DACHPt)-loaded polymeric micelles2005

    • Author(s)
      H. Cabral, N. Nishiyama, S. Okazaki, H. Koyama, K. Kataoka
    • Journal Title

      J. Control. Release 101(1-3)

      Pages: 223-232

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Lactosylated Poly(ethylene glycol)-siRNA conjugate through acid-Labile β-thiopropionate linkage to construct pH-sensitive polyion complex micelles achieving enhanced gene silencing in hepatoma cells2005

    • Author(s)
      M.Oishi, Y.Nagasaki, K.Itaka, N.Nishiyama, K.Kataoka
    • Journal Title

      J.Amer.Chem.Soc. 127(6)

      Pages: 1624-2625

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14380391
  • [Journal Article] Preparation and biological properties of dichloro(1,2-diaminocyclohexane) platinum(II)(DACHPt)-loaded polymeric micelles2005

    • Author(s)
      H.Cabral, Kataoka et al.
    • Journal Title

      J.Control.Release 101・1-3

      Pages: 223-232

    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Light-induced gene transfer from packaged DNA enveloped in a dendrimeric photosensitizer2005

    • Author(s)
      N. Nishiyama, A. Iriyama, W. -D. Jang, K. Miyata, K. Itaka, Y. Inoue, H. Takahashi, Y. Yanagi, Y. Tamaki, H. Koyama, K. Kataoka
    • Journal Title

      Nature Mater 4(12)

      Pages: 934-341

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Lactosy-lated Poly(ethylene glycol)-siRNA conjugate through acid-labile β-thiopropionate linkage to const-ruct pH-sensitive polyion complex micelles achieving enhanced gene silencing in hepatoma cells2005

    • Author(s)
      M.Oishi, Y.Nagasaki, K.Itaka, N.Nishiyama, K.Kataoka
    • Journal Title

      J.Am.Chem.Soc. 127(6)

      Pages: 1624-1625

    • Data Source
      KAKENHI-PROJECT-14380391
  • [Journal Article] Preparation and biological properties of dichloro(1,2-diaminocyclohexane)platinum(II) (DACHPt)-loaded polymeric micelles2005

    • Author(s)
      Cabral H, Nishiyama N, Koyama H, Kataoka K et al.
    • Journal Title

      J.Control.Release 101

      Pages: 223-232

    • Data Source
      KAKENHI-PROJECT-15390373
  • [Journal Article] Nanotechnologh-based photodynamic therapy for neovascular disease using a supramolecular nanocarrier loaded with a dendritic photosensitizer2005

    • Author(s)
      R. Ideta, F. Tasaka, W. -D. Jang, N. Nishiyama, G. -D. Zhang, A. Harada, Y. Yanagi, Y. Tamaki, T. Aida, K. Kataoka
    • Journal Title

      Nano Lett. 5(12)

      Pages: 2426-2431

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Supramolecular nanocarrier of anionic dendrimer prophyrins with cationic block copolymers modified with poly(ethylene glycol) to enhance intracellular photodynamic efficacy.2005

    • Author(s)
      Jang WD, Nishiyama N, Koyama H, Kataoka K, et al.
    • Journal Title

      Angew. Chem. Int. Ed. Engl 44

      Pages: 419-423

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390373
  • [Journal Article] Stabilization of lysozyme-incorporated polyion complex micelles by the ω-end derivatization of poly(ethylene glycol)-poly (α,β-aspartic acid) block copolymers with hydrophobic groups2005

    • Author(s)
      X. Yuan, A. Harada, Y. Yamasaki, K. Kataoka
    • Journal Title

      Langmuir 21(7)

      Pages: 2668-2674

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] NK105, a paclitaxel-incorporating micellar nanoparticle formulation, can extend in vivo antitumour activity and reduce the neurotoxicity of paclitaxel2005

    • Author(s)
      Hamaguchi, T., Kataoka, K.et al.
    • Journal Title

      British Journal of Cancer 92(7)

      Pages: 1240-1246

    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] NK105 a paclitaxel-incorporating micellar nanoparticle formulation, can extend in vivo antitumour activity and reduce the neurotoxicity of paclitaxel2005

    • Author(s)
      T.Hamaguchi, K.kataoka et al.
    • Journal Title

      Br.J.Cancer 92・7

      Pages: 1240-1246

    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Stabilization of lysozyme-incorporated polyion complex micelles by the ω-end derivatization of poly (ethylene glycol)-poly (α, β-aspartic acid) block copolymers with hydrophobic groups.2005

    • Author(s)
      X. Yuan, K. Kataoka et al.
    • Journal Title

      Langmuir 21

      Pages: 2668-2674

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Preparation and biological characterization of polymeric micelle drug carriers with intracellular pH-triggered drug release property : Tumor permeability, controlled subcellular drug distribution, and enhanced in vivo antitumor efficacy2005

    • Author(s)
      Y. Bae, N. Nishiyama, S. Fukushima, H. Koyama, Y. Matsumura, K. Kataoka
    • Journal Title

      Bioconjugate Chem. 16(1)

      Pages: 122-130

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Supramolecular nanocarrier of anionic dendrimer porphyrins with cationic block copolymers modified with poly (ethylene glycol) to enhance intracellular photodynamic efficacy.2005

    • Author(s)
      Jang WD, Nishiyama N, Koyama H, Kataoka K, et al.
    • Journal Title

      Angew.Chem.Int.Ed.Engl 44

      Pages: 419-423

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390373
  • [Journal Article] PE Gylated polyplex micelles from triblock catiomers with spatially ordered layering of condensed pDNA and buffering units for enhanced intracellular genedelivery.2005

    • Author(s)
      S. Fukushima, K. Kataoka et al.
    • Journal Title

      J. Am. Chem. Soc. 127

      Pages: 2810-2811

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] PEGylated polyplex micelles from triblock catiomers with spatially ordered layering of condensed pDNA and buffering units for enhanced intracellular gene delivery2005

    • Author(s)
      Fukushima, S., Kataoka, K.et al.
    • Journal Title

      Journal of the American Chemical Society 127(9)

      Pages: 2810-2811

    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Preparation and biological characterization of polymeric micelle drug carriers with intracellular pH-triggered drug release property. Tumor permeability, controlled subcellular drug distribution, and enhanced in vivo antitumor efficacy2005

    • Author(s)
      Y.Bac, K.Kataoka et al.
    • Journal Title

      Bioconjug.Chem. 16・1

      Pages: 122-130

    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Supramolecular nanocarrier of anionic dendrimer porphyrins with cationic block copolymers modified with poly (ethylene glycol) to enhance intracellular photodynamicefficacy.2005

    • Author(s)
      W. -D. Jang, K. Kataoka et al.
    • Journal Title

      Angew. Chem. Int. Ed. 44

      Pages: 419-423

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Cisplatin-incorporating polymeric micelles (NC-6004) can reduce nephrotoxicity and neurotoxicity of cisplatin in rats2005

    • Author(s)
      H.Uchino, Kataoka et al.
    • Journal Title

      Br.J.Cancer 93・6

      Pages: 678-687

    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Lactosylated poly (ethylene glycol)-siRNA conjugate through acid-labile β-thiopropionate linkage to construct pH-sensitive polyion complex micelles achieving enhanced gene silencing in hepatoma cells2005

    • Author(s)
      M. Oishi, Y. Nagasaki, K. Itaka, N. Nishiyama, K. Kataoka
    • Journal Title

      J. Am. Chem. Soc. 127(6)

      Pages: 1624-1625

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] PEGylated polyplex micelles from triblock catiomers with spatially ordered layering of condensed pDNA and buffering units for enhanced intracellular gene delivery2005

    • Author(s)
      S. Fukushima, K. Miyata, N. Nishiyama, N. Kanayama, Y. Yamasaki, K. Kataoka
    • Journal Title

      J. Am. Chem. Soc. 127(9)

      Pages: 2810-2811

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] NK105, a paclitaxel-incorporating micellar nanoparticle formulation, can extend in vivo antitumour activity and reduce the neurotoxicity of paclitaxel2005

    • Author(s)
      T. Hamaguchi, Y. Matsumura, M. Suzuki, K. Shimizu, R. Goda, I. Nakamura, I. Nakatomi, M. Yokoyama, K. Kataoka, T. Kakizoe
    • Journal Title

      Br. J. Cancer 92

      Pages: 1240-1246

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Multifunctional polymeric micelles with folate-mediated cancer cell targeting and pH-triggered drug releasing properties for active intracellular drug delivery2005

    • Author(s)
      Y.Bae, K.Kataoka et al.
    • Journal Title

      Molecular BioSystems 1・3

      Pages: 242-250

    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Multifunctional polymeric micelles with folate-mediated cancer cell argeting and pH-triggered drug releasing properties for active intracellular drug delivery2005

    • Author(s)
      Y. Bae, W. -D. Jang, N. Nishiyama, S. Fukushima, K. Kataoka
    • Journal Title

      Mol. BioSyst 1(3)

      Pages: 242-250

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Preparation and biological properties dichloro (1, 2-diaminocyclohexane) platinum (II) (DACHPt)-loaded polymeric micelles2005

    • Author(s)
      Cabral H, Nishiyama N, Koyama H, Kataoka K, et al.
    • Journal Title

      J.Contorol.Release 101

      Pages: 223-232

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390373
  • [Journal Article] Smart polyion complex micelles for targeted intracellular delivery of PEGylated antisense oligonucleotide with acid-labile linkage2005

    • Author(s)
      M.Oishi, S.Sasaki, Y.Nagasaki, K.Kataoka
    • Journal Title

      Chem Bio Chem (on the Web)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14380391
  • [Journal Article] Preparation and biological characterization of polymeric micelle drug carries with intracellular pH-triggered property : Tumor permeability, controlled subsellular drug distribution, and enhanced in vivo antitumor efficacy2005

    • Author(s)
      Bae Y, Nishiyama N, Koyama H, Kataoka K, et al.
    • Journal Title

      Bioconjug. Chem. 16

      Pages: 122-130

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390373
  • [Journal Article] Lactosylated poly (ethylene glycol)-si RNA conjugate through acid-labile β-thiopropionate linkage to construct pH-sensitive polyion complex micelles achieving enhanced gene silencing in hepatoma cells.2005

    • Author(s)
      M. Oishi, K. Kataoka et al.
    • Journal Title

      J. Am. Chem. Soc. 127

      Pages: 1624-1625

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Preparation and biological characterization of polymeric micelle drug carriers with intracellular pH-triggered drug release property : Tumor permeability, controlled subcellular drug distribution, and enhanced in vivo antitumor efficacy2005

    • Author(s)
      Bae Y, Nishiyama N, Koyama H, Kataoka K et al.
    • Journal Title

      Bioconjug.Chem. 16

      Pages: 122-130

    • Data Source
      KAKENHI-PROJECT-15390373
  • [Journal Article] A synthetic block copolymer regulates S1 nuclease fragmentation of supercoiled plasmid DNA2005

    • Author(s)
      Osada, K., Kataoka, K.et al.
    • Journal Title

      Angewandte Chemie, International Edition 44(23)

      Pages: 3544-3548

    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Light-induced gene transfer from packaged DNA enveloped in a dendrimeric photosensitizer2005

    • Author(s)
      Nishiyama N, Koyama H, Kataoka K, et al.
    • Journal Title

      Nature Material 4

      Pages: 934-941

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390373
  • [Journal Article] Preparation and biological characterization of polymeric micelle drug carriers with intracellular PH-triggered drug release property : Tumor permeability, controlled subcellular drug distribution, and enhanced in vivo antitumor efficacy2005

    • Author(s)
      Bae Y, Nishiyama N, Koayama H, Kataoka K, et al.
    • Journal Title

      Bioconjug.Chem. 16

      Pages: 122-130

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390373
  • [Journal Article] Smart polyion complex micelles for targeted intracellular delivery of PEGylated antisense oligonucleotide with acid-labile linkage2005

    • Author(s)
      M.Oishi, S.Sasaki, Y.Nagasaki, K.Kataoka
    • Journal Title

      ChemBioChem 6(4)

      Pages: 718-725

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14380391
  • [Journal Article] Light-induced gene transfer from packaged DNA enveloped in a dendrimeric photosensitizer2005

    • Author(s)
      Nishiyama, N., Kataoka, K.et al.
    • Journal Title

      Nature Materials 4(12)

      Pages: 934-941

    • Data Source
      KAKENHI-PROJECT-17016017
  • [Journal Article] Preparation and biological properties of dichloro(1,2-diaminocyclohexane)platinum(II) (DACHPt)-loaded polymeric micelles2005

    • Author(s)
      Cabral H, Nishiyama N, Koyama H, Kataoka K, et al.
    • Journal Title

      J. Control. Release 101

      Pages: 223-232

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390373
  • [Journal Article] A synthetic blockcopolymer regulates S1 nuclease fragmentation of supercoiled plasmid DNA2005

    • Author(s)
      K. Osada, Y. Yamasaki, S. Katayose, K. Kataoka
    • Journal Title

      Angew. Chem. Int. Ed. 44(23)

      Pages: 3544-3548

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] PEGylated Polyplex Micelles from Triblock Catiomers with Spatially Ordered Layering of Condensed pDNA and Buffeting Units for Enhanced Intracellular Gene Delivery2005

    • Author(s)
      S.Fukushima, K.Miyata, N.Nishiyama, N.Kanayama, Y.Yamasaki, K.Kataoka
    • Journal Title

      J.Amer.Chem.Soc. 127(9)

      Pages: 2810-2811

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14380391
  • [Journal Article] Freeze-dried formulations for in vivo gene delivery of PEGylated polyplex micelles with disulfide crosslinked cores to the liver2005

    • Author(s)
      K. Miyata, Y. Kakizawa, N. Nishiyama, Y. Yamasaki, T. Watanabe, M. Kohara, K. Kataoka
    • Journal Title

      J. Control. Release 109(1-3)

      Pages: 15-23

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] Cisplatin-incorporating polymeric micelles (NC-6004) can reduce nephrotoxicity and neurotoxicity of cisplatin in rats2005

    • Author(s)
      H. Uchino, Y. Matsumura, T. Negishi, F. Koizumi, T. Hayashi, T. Honda, N. Nishiyama, K. Kataoka, S. Naito, T. Kakizoe
    • Journal Title

      Br. J. Cancer 93(6)

      Pages: 678-687

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17200031
  • [Journal Article] PEGylated polyplex micelles from triblock catiomers with spatially-ordered layering of condensed pDNA and buffering units for enhanced intracellular gene delivery2005

    • Author(s)
      S.Fukushima, K.Miyata, N.Nishiyama, N.Kanayama, Y.Yamasaki, K.Kataoka
    • Journal Title

      J.Am.Chem.Soc. 127(9)

      Pages: 2810-2811

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14380391
  • [Journal Article] A synthetic block copolymer regulates S1 nuclease fragmentation of super-coiled plasmid DNA2005

    • Author(s)
      K.Osada, Y.Yamasaki, S.Katayose, K.Kataoka
    • Journal Title

      Angew.Chem., Int'l. Ed (印刷中)

    • Data Source
      KAKENHI-PROJECT-14380391
  • [Journal Article] In situ single cell observation by fluorescence resonance energy transfer reveals fast intra-cytoplasmic delivery and easy release of plasmid DNA complexed with linear polyethylenimine2004

    • Author(s)
      K.Itaka, A.Harada, Y.Yamasaki, K.Nakamura, H.Kawaguchi, K.Kataoka
    • Journal Title

      J.Gene Med. 6(1)

      Pages: 76-84

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14380391
  • [Journal Article] Versatile Synthesis of End-functionalized Thermosensitive Poly(2-isopropyl-2-oxazolines)2004

    • Author(s)
      J.S.Park, Y.Akiyama, F.M.Winnik, K.Kataoka
    • Journal Title

      Macromolecules 37(18)

      Pages: 6786-6792

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14380391
  • [Journal Article] Block catiomer polyplexes with regulated densities of charge and disulfide cross-linking directed to enhance gene expression2004

    • Author(s)
      K.Miyata, Y.Kakizawa, N.Nishiyama, A.Harada, Y.Yamasaki, H.Koyama, K.Kataoka
    • Journal Title

      J.Am.Chem.Soc. 126(8)

      Pages: 2355-2361

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14380391
  • [Journal Article] Lactose-installed polyion complex micelles incorporating plasmid DNA as a targetable gene vector system : Their preparation and gene transfecting efficiency against cultured HepG2 cells2004

    • Author(s)
      D.Wakebayashi, N.Nishiyama, Y.Yamasaki, K.Itaka, N.Kanayama, A.Harada, Y.Nagasaki, K.Kataoka
    • Journal Title

      J.Controlled Release 95(3)

      Pages: 653-664

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14380391
  • [Journal Article] Block copolymer-coated calcium-phosphate nanoparticles sensing intracellular environment for oligodeoxynucleotide and siRNA delivery2004

    • Author(s)
      Y.Kakizawa, S.Furukawa, K.Kataoka
    • Journal Title

      J.Controlled Release 97(2)

      Pages: 345-356

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14380391
  • [Journal Article] Effective accumulation of polyion complex micelle to experimental choroidal neovascularization in rats2004

    • Author(s)
      R.Ideta, Y.Yanagi, Y.Tamaki, F.Tasaka.A.Harada, K.Kataoka
    • Journal Title

      FEBS Lett. 557(1-3)

      Pages: 21-25

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14380391
  • [Journal Article] In situ single cell observation by fluorescence resonance energy transfer reveals fast intra-cytoplasmic delivery and easy release of plasmid DNA complexed with linear polyethylenimine2004

    • Author(s)
      K.Itaka, A.Harada, Y.Yamasaki, K.Nakamura, H.Kawaguchi, K.Kataoka
    • Journal Title

      J. Gene Med. 6(1)

      Pages: 76-84

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14380391
  • [Journal Article] Block catiomer polyplexes with regulated densities of charge and disulfide cross-linking directed to enhance gene expression.2004

    • Author(s)
      Miyata K, Koyama H, Nishiyama N, Kataoka, K et al.
    • Journal Title

      Journal of American Chemical Society 126

      Pages: 2355-2361

    • Data Source
      KAKENHI-PROJECT-15390373
  • [Journal Article] Synthesis of heterotelechelic poly(ethylene glycol) derivatives having α-benzaldehyde and ω-pyridyl disulfide groups by ring opening polymerization of ethylene oxide using 4-(diethoxymethyl)benzyl alkoxide as a novel initiator2004

    • Author(s)
      Y.Akiyama, Y.Nagasaki, K.Kataoka
    • Journal Title

      Bioconjugate Chemistry 15(2)

      Pages: 424-427

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14380391
  • [Journal Article] Supramolecular nanocarrier of siRNA from PEG-based block catiomer carrying diamine side-chain with distinctive pKa directed to enhance intracellular gene silencing2004

    • Author(s)
      K.Itaka, N.Kanayama, N.Nishiyama, Y.Yamasaki, K.Nakamura, H.Kawaguchi, K.Kataoka
    • Journal Title

      J.Am.Chem.Soc. 126(42)

      Pages: 13612-13613

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14380391
  • [Journal Article] Block catiomer polyplexes with regulated densities of charge and disulfide cross-linking directed to enhance gene expression2004

    • Author(s)
      K.Miyata, Y.Kakizawa, N.Nishiyama, A.Harada, Y.Yamasaki, H.Koyama, K.Kataoka
    • Journal Title

      J.Amer.Chem.Soc. 126(8)

      Pages: 2355-2361

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14380391
  • [Journal Article] Effective accumulation of polyion complex micelle to experimental choroidal neovascularization in rats2004

    • Author(s)
      R.Ideta, Y.Yanagi, Y.Tamaki, F.Tasaka, A.Harada, K.Kataoka
    • Journal Title

      FEBS Lett. 557(1-3)

      Pages: 21-25

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14380391
  • [Journal Article] Microcalorimetric Study of the Temperature-Induced Phase Separation in Aqueous Solutions of Poly(2-isopropyl-2-oxazolines)2004

    • Author(s)
      C.Drab, Y.Akiyama, K.Kataoka, F.M.Winnik
    • Journal Title

      Macromolecules 37(7)

      Pages: 2556-2562

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14380391
  • [Journal Article] Block catiomer polyplexes with regulated densities of charge and disulfide cross-linking directed to enhance gene expression.2004

    • Author(s)
      Miyata K, Koyama H, Kataoka K et al.
    • Journal Title

      Journal of American Chemical Society 126

      Pages: 2355-2361

    • Data Source
      KAKENHI-PROJECT-15390536
  • [Journal Article] Lactose-installed polyion complex micelles incorporating plasmid DNA as a targetable gene vector system : Their preparation and gene transfecting efficiency against cultured HepG2 cells2004

    • Author(s)
      D.Wakebayashi, N.Nishiyama, Y.Yamasaki, K.Itaka, N.Kanayama, A.Harada.Y.Nagasaki, K.Kataoka
    • Journal Title

      J. Controlled Release 95(3)

      Pages: 653-654

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14380391
  • [Journal Article] Supramolecular nanocarrier of siRNA from PEG-based block catiomer carrying diamine side-chain with distinctive pKa directed to enhance intracellular gene silencing2004

    • Author(s)
      K.Itaka, N.Kanayama, N.Nishiyama, Y.Yamasaki, K.Nakamura, H.Kawaguchi, K.Kataoka
    • Journal Title

      J.Amer.Chem.Soc. 126(42)

      Pages: 13612-13613

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14380391
  • [Journal Article] Microcalorimetric Study of the Temperature-Induced Phase Separation in Aqueous Solutions of Poly(2-isopropyl-2-oxazolines)2004

    • Author(s)
      C.Diab, Y.Akiyama, K.Kataoka, F.M.Winnik
    • Journal Title

      Macromolecules 37(7)

      Pages: 2556-2562

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14380391
  • [Journal Article] Block catiomer polyplexes with regulated densities of charge and disulfide cross-linking directed to enhance gene expression.2004

    • Author(s)
      Miyata K, Koyama H, Kataoka K et al.
    • Journal Title

      Journal of American Chemical Society 126

      Pages: 2355-2361

    • Data Source
      KAKENHI-PROJECT-16390506
  • [Journal Article] Size-controlled formation of a calcium phosphate-based organic-inorganic hybrid vector for gene delivery using poly(ethylene glycol)-block-poly(aspartic acid)2004

    • Author(s)
      Y.Kakizawa, K.Miyata, S.Furukawa, K.Kataoka
    • Journal Title

      Advanced Materials 16(8)

      Pages: 699-702

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14380391
  • [Journal Article] Synthesis of heterotelechelic poly(ethylene glycol) derivatives having □-benzaldehyde and □-pyridyl disulfide groups by ring opening polymerization of ethylene oxide using 4-(diethoxymethyl)benzyl alkoxide as a novel initiator2004

    • Author(s)
      Y.Akiyama, Y.Nagasaki, K.Kataoka
    • Journal Title

      Bioconjugate Chemistry 15(2)

      Pages: 424-427

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14380391
  • [Journal Article] Polyion complex micelles of pDNA with acetal-poly(ethylene glycol)-poly(2-(dimethylamino)ethyl methacrylate) block copolymer as gene carrier systems : Physicochemical properties of micelles relevant to gene transfection efficacy2004

    • Author(s)
      D.Wakebayashi, N.Nishiyama, K.Itaka, K.Miyata, Y.Yamasaki, A.Harada, H.Koyama, Y.Nagasaki, K.Kataoka
    • Journal Title

      Biomacromolecules 5(6)

      Pages: 2128-2136

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14380391
  • [Journal Article] Block copolymer-coated calcium-phosphate nanoparticles sensing intracellular environment for oligodeoxynucleotide and siRNA delivery2004

    • Author(s)
      Y.Kakizawa, S.Furukawa, K.Kataoka
    • Journal Title

      J. Controlled Release 97(2)

      Pages: 345-356

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14380391
  • [Journal Article] pH-Responsive Oligodeoxynucleotide (ODN)-Poly(Ethylene Glycol) Conjugate through Acid-Labile β-Thiopropionate Linkage : Preparation and Polyion Complex Micelle Formation2003

    • Author(s)
      M.Oishi, S.Sasaki, Y.Nagasaki, K.Kataoka
    • Journal Title

      Biomacromolecules 4(5)

      Pages: 1426-1432

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14380391
  • [Journal Article] Polyion complex micelles from plasmid DNA and poly(ethylene glycol)-poly(L-lysine) block copolymer as serum-tolerable polyplex system : Physicochemical properties of micelles relevant to gene transfection efficiency2003

    • Author(s)
      K.Itaka, K.Yamauchi, A.Harada, K.Nakamura, H.Kawaguchi, K.Kataoka
    • Journal Title

      Biomaterials 24(24)

      Pages: 4495-4506

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14380391
  • [Journal Article] Effect of charged segment length on physicochemical properties of core-shell type polyion complex micelles from block ionomers2003

    • Author(s)
      A.Harada, K.Kataoka
    • Journal Title

      Macromolecules 36(13)

      Pages: 4995-5001

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14380391
  • [Journal Article] PEG-PLL block copolymers induce reversible large discrete coil-globule transition in a single DNA molecule through cooperative complex formation2003

    • Author(s)
      Y.Yamasaki, S.Katayose, K.Kataoka, K.Yoshikawa
    • Journal Title

      Macromolecules 36(16)

      Pages: 6276-6279

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14380391
  • [Journal Article] Lactose-installed poly(ethylene glycol)-poly(D, L-lactide) block copolymer micelles exhibit fast-rate binding and high affinity towards a protein bed simulatin (g a cell surface. A surface plasmon resonance study2003

    • Author(s)
      E.Jule, Y.Nagasaki, K.Kataoka
    • Journal Title

      Bioconjugate Chemistry 14(1)

      Pages: 177-186

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14380391
  • [Journal Article] A surface plasmon resonance study on the interaction between lactose-installed polyethylene glycol)-poly(D, L-lactide) block copolymer micelles and lectins immobilized on a gold surface2002

    • Author(s)
      E.Jule, Y.Nagasaki, K.Kataoka
    • Journal Title

      Langmuir 18(26)

      Pages: 10334-10339

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14380391
  • [Journal Article] A surface plasmon resonance study on the interaction between lactose-installed poly(ethylene glycol)-poly(D, L-lactide) block copolymer micelles and lectins immobilized on a gold surface2002

    • Author(s)
      E.Jule, Y.Nagasaki, K.Kataoka
    • Journal Title

      Langmuir 18(26)

      Pages: 10334-10339

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14380391
  • [Journal Article] Polymeric micelles incorporating (1,2-diaminocyclohexane)platinum (II) suppress the growth of orthotopic scirrhous gastric tumors and their lymph node metastasis

    • Author(s)
      M.Rafi, H.Cabral, M.R.Kano, P.Mi, C.Iwata, M.Yashiro, K.Hirakawa, K.Miyazono, N.Nishiyama, K.Kataoka
    • Journal Title

      J.Control.Release

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23350049
  • [Journal Article] Effective transgene expression without toxicity by intraperitoneal administration of PEG-detachable polyplex micelles in mice with peritoneal dissemination

    • Author(s)
      Kumagai M, Shimoda S, Wakabayashi R, Kunisawa Y, Ishii T, Osada K, Itaka K, Nishiyama N, Kataoka K, Nakano K
    • Journal Title

      J Control Release

      Volume: (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390374
  • [Journal Article] A novel homogeneous irradiation fiber probe for whole bladder wall photodynamic therapy

    • Author(s)
      K.Miyazaki, Y.Morimoto, N.Nishiyama, Y.Maekawa, W.-Z.Hu, K.Nakatate, K.Kaneda, N.Shinomiya, K.Kataoka
    • Journal Title

      Lasers Surg.Med.

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23350049
  • [Journal Article] Antiangiogenic gene therapy of experimental pancreatic tumor by sFlt-1 plasmid DNA carried by RGD-modified crosslinked polyplex micelles

    • Author(s)
      Y. Vachutinsky, M. Oba, K. Miyata, S. Hiki, M.R. Kano, N. Nishiyama, H. Koyama, K. Miyazono, K. Kataoka
    • Journal Title

      J. Control. Release (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016017
  • [Patent] ゲノム編集用ミセル2020

    • Inventor(s)
      片岡 一則,内田 智士,アッバシ サエド
    • Industrial Property Rights Holder
      川崎市産業振興財団
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2020-113434
    • Filing Date
      2020
    • Data Source
      KAKENHI-PROJECT-19F19116
  • [Patent] 抗体の抗原結合性断片を脳へ送達するための方法および組成物2019

    • Inventor(s)
      安楽泰孝、片岡一則、Jinbing Xie、中村乃理子
    • Industrial Property Rights Holder
      公益財団法人川崎市産業振興財団
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2019-085661
    • Filing Date
      2019
    • Data Source
      KAKENHI-PROJECT-16F16357
  • [Patent] 体内における薬物動態を制御する組成物2019

    • Inventor(s)
      片岡一則、内田智士、大澤重仁、林光太郎、藤加珠子、等
    • Industrial Property Rights Holder
      川崎市産業振興財団
    • Industrial Property Rights Type
      特許
    • Filing Date
      2019
    • Overseas
    • Data Source
      KAKENHI-PROJECT-20K20386
  • [Patent] mRNA送達用キャリアおよびこれを含む組成物2018

    • Inventor(s)
      片岡一則、ディリサラ アンジャネユル、内田智士
    • Industrial Property Rights Holder
      川崎市産業振興財団
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2018-156804
    • Filing Date
      2018
    • Data Source
      KAKENHI-PROJECT-20K20386
  • [Patent] 脳への薬剤送達用のキャリアおよびこれを含んでなる組成物2018

    • Inventor(s)
      片岡一則、安楽泰孝、中村乃理子
    • Industrial Property Rights Holder
      川崎市産業振興財団
    • Industrial Property Rights Type
      特許
    • Filing Date
      2018
    • Overseas
    • Data Source
      KAKENHI-PROJECT-18H04170
  • [Patent] 脳への薬剤送達用のキャリアおよびこれを含んでなる組成物2018

    • Inventor(s)
      片岡一則、安楽泰孝、中村乃理子
    • Industrial Property Rights Holder
      川崎市産業振興財団
    • Industrial Property Rights Type
      特許
    • Filing Date
      2018
    • Overseas
    • Data Source
      KAKENHI-PROJECT-20K20386
  • [Patent] 血中で安定なmRNA内包ミセル2018

    • Inventor(s)
      大澤重仁、長田健介、片岡一則
    • Industrial Property Rights Holder
      川崎市産業振興財団
    • Industrial Property Rights Type
      特許
    • Filing Date
      2018