Akaike Toshihiro 赤池敏宏

… Alternative Names

Researcher Number	30101207
Other IDs
External Links
Affiliation (Current)	2019: 公益財団法人国際科学振興財団, その他部局等, 主席研究員
Affiliation (based on the past Project Information) *help	2017 – 2019: 公益財団法人国際科学振興財団, その他部局等, 主席研究員 2014: 公益財団法人国際科学振興財団, 再生医工学バイオマテリアル研究所, 所長 2014: 東京工業大学, 大学院生命理工学研究科, 教授 2012 – 2013: 東京工業大学, 生命理工学研究科, 特任教授 2012: 東京工業大学, 学内共同利用施設等, 教授 … More
Review Section/Research Field	Principal Investigator Biomedical engineering/Biological material science / Biomedical engineering/Biological material science / Science and Engineering / Chemistry related to living body / Bioorganic chemistry / Biomedical engineering/Biomaterial science and engineering Except Principal Investigator Biomedical engineering/Biological material science / Biomedical engineering/Biological material science / Microdevices/Nanodevices / General surgery … More
Keywords	Principal Investigator 肝細胞 / PVLA / 細胞接着 / 細胞外マトリックス / 再生医療 / アシアロ糖タンパク質 / 人工肝臓 / E-カドヘリン / アシアロ糖タンパク質モデル / 人工血管 … More Except Principal Investigator 細胞培養 / PVLA / 肝炎 / サイトカイン / ハイドロゲル / 再生医療 / 高分子ゲル / 再生医工学 / 細胞外マトリックス / コラーゲン / 人工血管 / アルブミン / 磁気共鳴画像診断 / 造影剤 / ポリイオンコンプレックス / pH応答性 / pH response / マイクロキャリア / 肝細胞移植 / 糖脂質 / スフィンゴ糖脂質 / 相転移 / 相分離 / 細胞接着因子 / 肝実質細胞 / ICAM-1 / 肝特異的マクロファージ / 分化 / 骨髄細胞 / 2光子励起重合 / 2光子吸収 / 二光子励起 / 光重合 / ナノパターンニング / アトリソグラフィー / 二光子励起重合 / 細胞牽引力 / マイクロニードルアレイ / 増殖・分化 / 癌 / 微小環境 / 浸潤 / 転移 / 炭酸アパタイト / ナノテクノロジー / DDS / 細胞・組織工学 / 積層型高密度培養 / コラーゲン細線維 / 血管再生 / PK15細胞 / バイオリアクター / ePTFE人工血管 / INTERGARD人工血管 / PLAシート / CBD-cytokine / PEAC細胞 / HepG2細胞 / 免疫不全マウス / マイクロRNA / アパタイトナノキャリア / がん遺伝子 / 胃がん / 担がん動物 / 細胞内導入 / 胃癌 / シスプラチン / 5-FU / NOGマウス / 癌幹細胞 / 食道腺癌 / 癌遺伝子 / 担癌動物 / バイオインターフェース / ナノバイオ / 表面分光 / 分子分光 / 表面科学 / バイオマテリアル / ラマン分光 / 国際情報交換 / 新生血管壁 / 平滑筋細胞 / 内皮細胞 / バイオマトリックス / 退行性変性 / 血管壁代謝 / 器官形成 / 発生生物学 / 臓器工学 / 細胞組み込型人工臓器 / 新しい生理機能 / 器官再構築 / 細胞接着 / ラミニン / フィブロネクチン / プロテオグリカン / インテグリン / コンドロイチン硫酸 / ビトロネクチン / シャペロン / コラ-ゲン / テネイシン / CELL ADHESION / EXTRACELLULAR MATRIX / COLLAGEN / LAMININ / FIBRONECTIN / PROTEOGLYCAN / INTEGRIN / CYTOKINE / バイオハイブリッド型人工膵島 / MIN6細胞 / インスリン分泌 / 糖尿病 / 人工臓器 / グルコーストランスポーター / バイオ人工膵島 / インスリン / diabetes / bioartificial endocrine pancreas / glucose transporter / MIN6 cell / insulin secretion / 人工複合糖質材料 / 細胞標的制御システム / 生体機能材料 / 糖鎖工学 / Polymer / Glycotechnology / Recognition / Materials Life Science / Influenza Virus / ガドリニウム / ガン / 水素イオン濃度 / 環境応答性 / インテリジェントマテリアル / T1 緩和能 / magnetic resonance imaging / contrast agent / polyion complex / gadolinium / tumor / 人工肝 / 肝細胞 / 伊東細胞 / 幹細胞 / マトリックス / アポトーシス / 細胞移植 / マイクロファブリケーション / マイクロファブレケーション / ステムセル / Artificial Liver Support / Mixed culture / Matrix / Stem cell / Apoptosis / Hepatocyte / Ito cell / Microfabrication / ドラッグデリバリー / 細胞死 / 肝レクチン / caspase / アシアロ糖タンパク質レセプター / Caspase / Hepatitis / Drug Delivery / Hepatic lectin / apoptosis / ガドリニウムイオン / ポリカチオン / ポリアニオン / 核磁気共鳴画像診断 / 高分子電解質複合体 / pH反応性 / コアセルベーション / ガドリヌウムイオン / 高分子電解執複合体 / 高分子化造影剤 / Gd ion / Polycation / Polyanion / Magnetic resonance imaging / Interpolyelectrolyte complex / Coacervation / Contrast agents / 腎臓糸球体細胞 / 肝臓細胞 / 分離培養 / 長期保存 / 細胞間相互作用 / PD(population doubling) / PD (population doubling) / 腎臓細胞 / 不死化 / 遺伝子発現 / tissue regeneration / renal glomerular cells / liver cells / co-culture / long term culture / cell-cell interaction / PD / mesangial cells / 標準化 / 培養基質 / AFM / カドヘリン / 肝臓学 / エクソソーム / 細胞認識性 Less

Molecular level evaluation of cell culture substrate and construction of nano-controlled surface toward cell culture standardizationOngoing
- Principal Investigator
  
  関禎子
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  Foundation for Advancement of International Science
細胞認識性エクソソームを用いた臓器線維症に対する革新的治療法の開発Ongoing
- Principal Investigator
  
  稲垣豊
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  Tokai University
Design of Highly EMT-recognizable CarbonateApataite Nano-particles for Organ-Fibrosis and CancerPrincipal InvestigatorOngoing
- Principal Investigator
  
  赤池敏宏
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Foundation for Advancement of International Science
Analysis of molecular processes between cells and artificial materials by surface-enhanced Raman spectroscopy
- Principal Investigator
  
  HAYASHI Tomohiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Tokyo Institute of Technology
Regulation of functions and differentiation of ES/iPS cells by designing cell-recognizable chimera matricesPrincipal Investigator
- Principal Investigator
  
  AKAIKE Toshihiro
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Foundation for Advancement of International Science
  Tokyo Institute of Technology
テーラーメイド治療への応用をめざすヒトiPS細胞の標準化培養器材の開発Principal Investigator
- Principal Investigator
  
  赤池敏宏
- Project Period (FY)
  2011
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Tokyo Institute of Technology
Generating artificial parenchymal and hollow organs fabricated with collagen fibrils,various cells, and cytokines using a bioreactor that we have developed
- Principal Investigator
  
  ADACHI Eijiro
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Kitasato University
The microRNAsfor the diagnosis and treatment of uppergastro-intestinal malignancy - application of appatite-nanocarrier -
- Principal Investigator
  
  SUZUKI Hidekazu
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Keio University
Integrated research for respective role of cancer and microenvironment towards clinical application
- Principal Investigator
  
  YAMAMOTO Hirofumi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Osaka University
炭酸アパタイトナノテクノロジーによる難治性固形癌の治療法の開発
- Principal Investigator
  
  山本浩文
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General surgery
- Research Institution
  Osaka University
Regulation of Stem Cells Gene Expression using Apatite nanocarriers coated with Cell-reconizable chimeric Protein.Principal Investigator
- Principal Investigator
  
  AKAIKE Toshihiro
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Tokyo Institute of Technology
アトリソグラフィーによる細胞制御デバイスの作製と再生医工学への応用
- Principal Investigator
  
  渡辺敏行
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Microdevices/Nanodevices
- Research Institution
  Tokyo University of Agriculture and Technology
遺伝子組換法による表面固定型キメラタンパク質の設計と再生医療用ES細胞の増殖制御Principal Investigator
- Principal Investigator
  
  赤池敏宏
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Chemistry related to living body
- Research Institution
  Tokyo Institute of Technology
三次元ナノパターンニング弾性基質の作製と再生医工学への応用
- Principal Investigator
  
  WATANABE Toshiyuki
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Microdevices/Nanodevices
- Research Institution
  Tokyo University of Agriculture and Technology
Design of Cell-Recognizable Nano-device and Application to Biosensing and Tissue-engineeringPrincipal Investigator
- Principal Investigator
  
  AKAIKE Toshihiro
- Project Period (FY)
  2003 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Tokyo Institute of Technology
肝細胞の薬物代謝と胆汁酸代謝の同調的制御による次世代型バイオ人工肝臓の設計Principal Investigator
- Principal Investigator
  
  赤池敏宏
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Tokyo Institute of Technology
Immortalization of liver, kidney cells and the functional estimation for the use of cell therapy
- Principal Investigator
  
  PI-CHAO Wang
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  University of Tsukuba
Physiological microenvironment-responsive contrast agent for magnetic resonance imaging
- Principal Investigator
  
  MARUYAMA Atsushi
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  高分子合成
- Research Institution
  Tokyo Institute of Technology
細胞における受容体シンクロナイゼーションの解析とモデル化Principal Investigator
- Principal Investigator
  
  赤池敏宏
- Project Period (FY)
  1999 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Tokyo Institute of Technology
Inventory of Artificial Liver Support based on the mixed culture system of Hepatocytes with Ito cells
- Principal Investigator
  
  ISHII Hiromasa
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Keio University
Mechanism of liver injury and design of drug delivery system for the liver.
- Principal Investigator
  
  WATANABE Yoshifumi
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Tokyo Institute of Technology
Molecular Synchronization for Design of New Materials SystemPrincipal Investigator
- Principal Investigator
  
  AKAIKE Toshihiro
- Project Period (FY)
  1998 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Tokyo Institute of Technology
Design of Polymeric Supramolecular-assembly for Targeted Therapy of LiverPrincipal Investigator
- Principal Investigator
  
  AKAIKE Toshihiro
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Tokyo Institute of Technology
Design of a cell specific macromolecular contrast agent for higher resolution of magnietic resonance imaging
- Principal Investigator
  
  MARUYAMA Atsushi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  TOKYO INSTITUTE OF TECHNOLOGY
DESIGN OF CELL SPECIFIC CARRIERS FOR GENES AND PEPTIDESPrincipal Investigator
- Principal Investigator
  
  AKAIKE Toshihiro
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  TOKYO INSTITUTE OF TECHNOLOGY
Construction of Cell-Targetting Systems by Artificial Glycoconjugate Polymers
- Principal Investigator
  
  KOBAYASHI Kazukiyo
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Nagoya University
糖脂質モデルによる糖鎖組織構造の制御と細胞機能制御
- Principal Investigator
  
  MARUYAMA Atsushi
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Institute of Technology
肝炎発症機構の免疫学的解析と治療のための薬物運搬用高分子材料の開発
- Principal Investigator
  
  渡邊恵史
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Tokyo Institute of Technology
肝特異的マクロファージの発生、分化の解析
- Principal Investigator
  
  渡邊恵史
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokyo Institute of Technology
Development of Superasialoglycoprotein models with combined functions of Liver-cells Recognition and Drugs-inclusionPrincipal Investigator
- Principal Investigator
  
  AKAIKE Toshihiro
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Tokyo Institute of Technology
DEVELOPMENT OF BIOARTIFICIAL ENDOCRINE PANCREAS USING GLUCOSE-RESPONSIVE B-CELL LINE MIN6
- Principal Investigator
  
  MIYAZAKI Jun-ichi
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Osaka University
  Tohoku University
インテリジェント型糖質高分子設計による肝細胞の接着・増殖・分化の制御Principal Investigator
- Principal Investigator
  
  赤池敏宏
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Institute of Technology
DEVELOPMENT OF SUPER-BIOARTIFICIAL LIVER BASED ON THE HEPATOCYTE-SPECIFIC POLYMER DESIGN AND GENETIC ENGINEERINGPrincipal Investigator
- Principal Investigator
  
  AKAIKE Toshihiro
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  TOKYO INSTITUTE OF TECHNOLOGY
Application of biodegradable Nanoparticles coated with sugar-carrying polymer to targetted drug deliveryPrincipal Investigator
- Principal Investigator
  
  AKAIKE Toshihiro, 丸山厚
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Tokyo Institute of Technology
組織器官形成促進材料Principal Investigator
- Principal Investigator
  
  赤池敏宏
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Institute of Technology
組織器官形成促進材料Principal Investigator
- Principal Investigator
  
  赤池敏宏
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Institute of Technology
肝細胞移植の新しい工夫:MICROCARRIERを用いる分離肝細胞の門脈内移植
- Principal Investigator
  
  杉本久之, 井上純雄
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  The University of Tokyo
THE ANALYSIS OF CELL ADHESION SIGNALS : POSSIBLE CLINICAL APPLICATIONS
- Principal Investigator
  
  HAYASHI Toshikiko
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  広領域
- Research Institution
  UNIVERSITY OF TOKYO
組織器官形成促進材料Principal Investigator
- Principal Investigator
  
  赤池敏宏
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Institute of Technology
臓器工学的応用を指向した器官形成の総合的研究
- Principal Investigator
  
  水野丈夫
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  動物発生・生理学
- Research Institution
  Teikyo University
生体ー材料間相互作用における複合効果の制御に関する研究Principal Investigator
- Principal Investigator
  
  赤池敏宏
- Project Period (FY)
  1987 – 1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo University of Agriculture and Technology
血管壁の修復過程およびそれに関与する細胞の配列と機能およびその由来について
- Principal Investigator
  
  野一色泰晴
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Okayama University
細胞-材料間相互作用における複合効果の発現に関する研究Principal Investigator
- Principal Investigator
  
  赤池敏宏
- Project Period (FY)
  1987 – 1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo University of Agriculture and Technology
生体ー材料間相互作用における複合効果の制御に関する研究Principal Investigator
- Principal Investigator
  
  赤池敏宏
- Project Period (FY)
  1987 – 1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo University of Agriculture and Technology
生体膜モデルの流動性制御による細胞応答の制御Principal Investigator
- Principal Investigator
  
  赤池敏宏
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Tokyo University of Agriculture and Technology
生体膜モデルの流動性制御による細胞応答の制御Principal Investigator
- Principal Investigator
  
  赤池敏宏
- Project Period (FY)
  1985 – 1987
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Tokyo University of Agriculture and Technology

[Book] NIMS　NOW2015
- Author(s)
  赤池敏宏、長崎幸夫、陳国平
- Publisher
  NIMS
- Data Source
  KAKENHI-PROJECT-23220014
[Book] BIOCOMPATIBLE APATITE NANO-PARTICLES:A VERSATILE TOOL FOR CELLULAR DELIVERY OF GENES,SIRNAS,DRUGS AND PROTEINS2014
- Author(s)
  Sharif Hossain,Ezharul Hoque Chowdhury,Nihad Adnan,Toshihiro Akaike
- Total Pages
  327
- Publisher
  NOVA
- Data Source
  KAKENHI-PROJECT-23220014
[Book] 細胞認識性バイオマテリアルの設計とその組織工学・DDSへの応用2014
- Author(s)
  赤池敏宏
- Publisher
  日本バイオマテリアル学会
- Data Source
  KAKENHI-PROJECT-23220014
[Book] Marine Biomaterials2013
- Author(s)
  You-Kyoung Kim, Hu-Lin Jiang, Bijay Singh,Yun-Laie Choi, Myung-Haing Cho, Toshihiro Akaike, Chong-Su Cho
- Total Pages
  840
- Publisher
  CRC Press
- Data Source
  KAKENHI-PROJECT-23220014
[Book] Bioengineered Nanomaterials2013
- Author(s)
  Sharif Hossain, Ezhurul Haque Chowdhury, Toshihiro Akaike
- Total Pages
  422
- Publisher
  CRC press
- Data Source
  KAKENHI-PROJECT-23220014
[Book] Bioengineered Nanomaterials2013
- Author(s)
  Sharif Hossain, Ezharul Hoque Chowdhury and Toshihiro Akaike,
- Publisher
  Taylor & Francis Publisher
- Data Source
  KAKENHI-PROJECT-23220014
[Book] Chitosan-Based Systems for Biopharmaceuticals. Delivery, Targeting and Polymer Therapeutics,2012
- Author(s)
  Y.K. Kim, H.L. Jiang, D.D. Guo, Y.J. Choi, M.H. Cho, T. Akaike, C.S. Cho,
- Publisher
  Jhon Wiley &Sons Ltd. Pub.
- Data Source
  KAKENHI-PROJECT-23220014
[Book] Stem cells and cancer stem cells　Vol. 6.2012
- Author(s)
  Amranul Haque and Toshihiro Akaike.
- Publisher
  Springer Science & Business Media B.V.
- Data Source
  KAKENHI-PROJECT-23220014
[Book] Differentiation of Embryonic Stem Cells into Endoderm-Derived Hepatocytes. Stem cells and cancer stem cells2012
- Author(s)
  A.Haque, Akaike T.
- Publisher
  Springer Science & Business Media B.V.(In Press)
- Data Source
  KAKENHI-PROJECT-23220014
[Book] The Handbook of intelligent Scaffold for Regenerative Medicine,2012
- Author(s)
  C.S. Cho H.L. Jiang, T. Hoshiba, T. Akaike,
- Publisher
  Pan Stanford Publishing Pte. Ltd.
- Data Source
  KAKENHI-PROJECT-23220014
[Book] 治療・診断のための医療材料システムの開発(再生医療と人工臓器・ドラッグデリバリーの最近の進歩中国・日本科学最前線-研究の現場から-2011年版)2010
- Author(s)
  赤池敏宏, 他1名
- Total Pages
  5
- Publisher
  科学技術振興機構
- Data Source
  KAKENHI-PROJECT-22300167
[Book] 再生医療と人工臓器・ドラッグデリバリーの最近の進歩-「治療・診断のための医療材料システムの開発」-中国・日本科学最前線-研究の現場から-2011年版2010
- Author(s)
  赤池敏宏他1名
- Total Pages
  5
- Publisher
  科学技術振興機構
- Data Source
  KAKENHI-PROJECT-22300167
[Book] 「炭酸アパタイトナノ粒子を利用した、新しい遺伝子・RNA・タンパク質の細胞内導入システム」分子細胞治療フロンティア20102010
- Author(s)
  沓沢好一, 赤池敏宏
- Total Pages
  8
- Publisher
  外科分子細胞治療研究会
- Data Source
  KAKENHI-PROJECT-19200038
[Book] 再生医療のためのバイオエンジニアリング(再生医療の基礎シリーズ4)2007
- Author(s)
  赤池敏宏
- Total Pages
  226
- Publisher
  コロナ社
- Data Source
  KAKENHI-PROJECT-19200038
[Book] 再生医療の基礎シリーズ4 再生医療のためのバイオエンジニアリング2007
- Author(s)
  赤池敏宏
- Total Pages
  226
- Publisher
  コロナ社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15100008
[Book] 再生医療の基礎シリーズ4 再生医療のためのバイオエンジニアリング2006
- Author(s)
  赤池敏宏
- Total Pages
  222
- Publisher
  コロナ社
- Data Source
  KAKENHI-PROJECT-17655074
[Book] 再生医療の基礎シリーズ4 再生医療のためのバイオエンジニアリング2006
- Author(s)
  赤池敏宏
- Total Pages
  222
- Publisher
  コロナ社
- Data Source
  KAKENHI-PROJECT-15100008
[Book] バイオテクノロジー教科書シリーズ122005
- Author(s)
  赤池敏宏
- Total Pages
  173
- Publisher
  コロナ社
- Data Source
  KAKENHI-PROJECT-15100008
[Book] 材料表面修飾とティッシュエンジニアリング:キメラタンパク質を用いた細胞接着応答の制御ティッシュエンジニアリング20052005
- Author(s)
  荻原一隆, 長岡正人, 赤池敏宏
- Publisher
  日本医学館
- Data Source
  KAKENHI-PROJECT-15100008
[Book] ティッシュエンジニアリング2005 田畑泰彦、岡野光夫編2005
- Author(s)
  荻原一隆, 長岡正人, 赤池敏宏
- Publisher
  日本医学館「材料表面修飾とティッシュエンジニアリング:キメラタンパク質を用いた細胞接着応答の制御」
- Data Source
  KAKENHI-PROJECT-17655074
[Journal Article] Radial Glial Fibers Promote Neuronal Migration and Functional Recovery after Neonatal Brain Injury2018
- Author(s)
  Jinnou H, Sawada M, Kawase K, Kaneko N, Herranz-Perez V, Miyamoto T, Kawaue T, Miyata T, Tabata Y, Akaike T, Garcia-Verdugo JM, Ajioka I, Saitoh S, Sawamoto K.
- Journal Title
  
  Cell Stem Cell
  
  Volume: 22 Pages: 128-137
- DOI
  10.1016/j.stem.2017.11.005
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07114, KAKENHI-PROJECT-17K18007, KAKENHI-PUBLICLY-17H05512, KAKENHI-PUBLICLY-17H05750, KAKENHI-PROJECT-16H02457, KAKENHI-PROJECT-17H01392, KAKENHI-PROJECT-18K14823, KAKENHI-PROJECT-17H02104
[Journal Article] Asymmetricity Between Sister Cells of Pluripotent Stem Cells at the Onset of Differentiation2018
- Author(s)
  S. Nakamura, A. Maruyama, Y. Kondo, A. Kano, O. M. De Sousa, M. Iwahashi, B. Hexig, T. Akaike, J. Li, Y. Hayashi and K. Ohnuma
- Journal Title
  
  Stem Cells and Development
  
  Volume: 27 Pages: 347-354
- DOI
  10.1089/scd.2017.0113
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H03889, KAKENHI-PROJECT-17H02104
[Journal Article] Radial Glial Fibers Promote Neuronal Migration and Functional Recovery after Neonatal Brain Injury.2018
- Author(s)
  Jinnou H, Sawada M, Kawase K, Kaneko N, Herranz-Pérez V, Miyamoto T, Kawaue T, Miyata T, Tabata Y, Akaike T, García-Verdugo JM, Ajioka I, Saitoh S, Sawamoto K.
- Journal Title
  
  Cell Stem Cell.
  
  Volume: 22 Pages: 128-137
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H02104
[Journal Article] Cadherin-Fc Chimeric Protein-Based Biomaterials:Advancing Stem Cell Technology and Regenerative Medicine Towards Application2015
- Author(s)
  Kakon Nag,Nihad Adnan,Koichi Kutsuzawa,Toshihiro Akaike
- Journal Title
  
  INTECH
  
  Volume: 1 Pages: 137-164
- DOI
  10.5772/58287
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23220014
[Journal Article] Innovative delivery of siRNA to solid tumors by super carbonate apatite.2015
- Author(s)
  Xin Wu, Hirofumi Yamamoto, Hiroyuki Nakanishi, Yuki Yamamoto, Akira Inoue, Mitsuyoshi Tei, Hajime Hirose, Mamoru Uemura, Junichi Nishimura, Taishi Hata, Ichiro Takemasa, Tsunekazu Mizushima, Sharif Hossain, Toshihiro Akaike, Nariaki Matsuura, Yuichiro Doki, Masaki Mori.
- Journal Title
  
  PLoS One
  
  Volume: March Pages: 1-21
- DOI
  10.1371/journal.pone.0116022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13J01119, KAKENHI-PROJECT-23220014, KAKENHI-PROJECT-15K10140
[Journal Article] AFM characterization of chemically treated corneal cells.2015
- Author(s)
  Teiko Shibata-Seki, Kazuki Tajima, Hiroki Takahashi, Hiroya Seki, Junji Masai, Hiroshi Goto, Eiry Kobatake, Toshihiro Akaike, Norihiko Itoh.
- Journal Title
  
  Anal Bioanal Chem
  
  Volume: 407 Pages: 2631-2635
- DOI
  10.1007/s00216-015-8473-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23220014
[Journal Article] A hybrid substratum for primary hepatocyte culture that enhances hepatic functionality with low serum dependency.2015
- Author(s)
  Qingyuan Meng, Chunsheng Tao,Zhiye Qiu, Toshihiro Akaike, Fuzhai Cui, Xiumei Wang.
- Journal Title
  
  Int J Nanomedicine
  
  Volume: 10 Pages: 2301-2323
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23220014
[Journal Article] バイオ人工肝臓へのチャレンジ　革新的バイオマテリアルとしてのカドヘリンマトリックス工学の応用2015
- Author(s)
  赤池敏宏、沓沢好一、荒津史裕、Kakon Nag
- Journal Title
  
  アークメディア｢肝胆膵」
  
  Volume: 70 Pages: 375-384
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23220014
[Journal Article] Dynamic chemotactic response of fibroblasts to local stimulation using EGF- immobilized microbeads2014
- Author(s)
  Aratsu, F., I. Harada, S. Yoshimura, C.-S. Cho, T. Akaike, Y. Tagawa
- Journal Title
  
  Biomaterials
  
  Volume: 35 Pages: 2471-2476
- DOI
  10.1016/j.biomaterials.2013.12.013
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-23119003, KAKENHI-PROJECT-23220014, KAKENHI-PROJECT-24604001, KAKENHI-PROJECT-25242040
[Journal Article] pH-sensitive carbonate apatite nanoparticles as DNA vaccine carriers enhance humoral cellular immunity.2014
- Author(s)
  Pan He, Shin-nosuke Takeshima, Seiichi Tada, Toshihiro Akaike,Yoshihiro Ito, Yoko Aida
- Journal Title
  
  Vaccine
  
  Volume: 34 Pages: 6199-6205
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23220014
[Journal Article] E-Cadherin-Fc Chimeric Protein-Based Biomaterial　Breaking the Barriers in Stem Cell Technology and Regenerative Medicine2014
- Author(s)
  Nag K, and Akaike T
- Journal Title
  
  Advanced Materials Research
  
  Volume: 801 Pages: 41-76
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23220014
[Journal Article] Direct observation of cell cycle progression in living mouse embryonic stem cell on an extracellular matrix of E-cadherin2013
- Author(s)
  Jovic D., Sakaue-Sawano A., Abe T., Cho CS., Nagaoka M., Miyawaki A., Akaike T.
- Journal Title
  
  Springer Plus
  
  Volume: 2
- DOI
  10.1186/2193-1801-2-585
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23220014
[Journal Article] In vivo organization of vascularized hepatic tissues model with fibroblast-embedded collagen fibrils formation at intraperitoneal sites in partially hepatectomised mice.2013
- Author(s)
  M. Tamai, T. Akaike, E. Adachi, and Y.Tagawa
- Journal Title
  
  Tissue Engineering PartA
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300167
[Journal Article] Imaging and therapy of liver fibrosis using bioreducible polyethylenimine/siRNA complexes conjugated with N-acetylglucosamine as a targeting moiety2013
- Author(s)
  Kim SJ., Ise H., Kim E., Goto M., Akaike T., Chung BH.
- Journal Title
  
  Biomaterials
  
  Volume: 34 Pages: 6504-6514
- DOI
  10.1016/j.biomaterials.2013.05.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23220014
[Journal Article] Artificial biomimicking matrix modifications of nanofibrous scaffolds by hE-cadherin-Fc fusion protein to promote human mesenchymal stem cells adhesion and proliferation2013
- Author(s)
  Xu J., Li S., Hu F., Zhu C., Zhang Y., Zhao W., Akaike T., Yang J.
- Journal Title
  
  Journal of Nanoscience and Nanotechnology
  
  Volume: 14 Pages: 4007-4013
- DOI
  10.1166/jnn.2014.8231
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23220014
[Journal Article] E-Cadherin-Fc Chimeric Protein-Based Biomaterial: Breaking the Barriers in Stem Cell Technology and Regenerative Medicine2013
- Author(s)
  Nag　K., Akaike T.
- Journal Title
  
  Advanced Materials Research
  
  Volume: 810 Pages: 41-76
- DOI
  10.4028/www.scientific.net/amr.810.41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23220014
[Journal Article] Effect of ursodeoxycholic acid and endoscopic sphincterotomy in long-term stenting for common bile duct stones.2013
- Author(s)
  Toshihiro Nishizawa
- Journal Title
  
  J. Gastroenterol. Hepatol.
  
  Volume: 28 Pages: 63-67
- DOI
  10.1111/jgh.12012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300169, KAKENHI-PROJECT-24659103, KAKENHI-PROJECT-25293178
[Journal Article] Fabrication and intracellular delivery of Doxorubicin/Carbonate Apatite Nanocomposites: Effiect on growth retardation of established Colon Tumor2013
- Author(s)
  Hossain S, Yamamoto H, Chowdhury EH, Wu x, Akaike T, et.al
- Journal Title
  
  PLoS ONE
  
  Volume: 8
- DOI
  10.1371/journal.pone.0060428
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11F01350, KAKENHI-PLANNED-22130005, KAKENHI-PROJECT-23220014
[Journal Article] hE-cadherin-Fc fusion protein coated surface enhances the adhesion and proliferation of human mesenchymal stem cells2013
- Author(s)
  Xu J., Zhu C., Zhang Y., Jiang N., Li S., Su Z., Akaike T., Yang J.
- Journal Title
  
  Colloids and surfaces B: Biointerfaces
  
  Volume: 109 Pages: 97-102
- DOI
  10.1016/j.colsurfb.2013.03.042
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23220014
[Journal Article] Fabrication and intracellular delivery of Doxorubicin/Carbonate Apatite Nanocomposites: Effiect on growth retardation of established Colon Tumor.2013
- Author(s)
  Hossain S, Akaike T, et. al.
- Journal Title
  
  PLoS One
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23220014
[Journal Article] The effects of artificial E-cadherin matrix-induced embryonic stem cell scattering on paxillin and RhoA activation via α-catenin2013
- Author(s)
  Mattias L., Haque A., Adnan N., Akaike T.
- Journal Title
  
  Biomaterials
  
  Volume: 35 Pages: 1797-1806
- DOI
  10.1016/j.biomaterials.2013.11.042
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23220014
[Journal Article] Bile acids increase levels of MicroRNAs 221 and 222, leading to degradation of CDX2 during esophageal carcinogenesis2013
- Author(s)
  J. Matsuzaki, H. Suzuki, H. Tsugawa, M. Watanabe, S. Hossain, T. Akaike, T. Hibi, et. al.
- Journal Title
  
  Gastroenterology
  
  Volume: (In Press) Pages: 1300-11
- DOI
  10.1053/j.gastro.2013.08.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11F01350, KAKENHI-PROJECT-23220014, KAKENHI-PROJECT-23580139, KAKENHI-PROJECT-23590482, KAKENHI-PROJECT-23680090, KAKENHI-PROJECT-24659103, KAKENHI-PROJECT-25293178, KAKENHI-PROJECT-25460173, KAKENHI-PROJECT-25460487
[Journal Article] Characterization and neural differentiation of mouse embryonic and induced pluripotent stem cells on cadherin-based substrata2012
- Author(s)
  A.Haque,X-S.Yue, A.Motazedian, Y.Tagawa, T.Akaike
- Journal Title
  
  Biomaterials
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23220014
[Journal Article] Interactions of vimentin-or desmin-expressing liver cells with N-acetylg lucosamine-bearing polymers2012
- Author(s)
  Kim SJ, Ise H, Goto M, Akaike T
- Journal Title
  
  Biomaterials
  
  Volume: 33 Pages: 2154-2164
- DOI
  10.1016/j.biomaterials.2011.11.084
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23220014
[Journal Article] Adsorption behaviors of recombinant E-cadherin-IgG Fc fusion protein on polystyrene surface.2012
- Author(s)
  Sakai S, Kim J, Hexig B, Okahata Y, Cho CS, Akaike T
- Journal Title
  
  Colloids Surf B Biointerfaces.
  
  Volume: 94 Pages: 192-8
- DOI
  10.1016/j.colsurfb.2012.01.031
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23220014
[Journal Article] The differentiation and isolation of mouse embryonic stem cells toward hepatocytes using galactose-carrying substrata2012
- Author(s)
  Meng Q., Haque A, Hexing B.Akaike T.
- Journal Title
  
  Biomaterials
  
  Volume: 33 Pages: 1414-1427
- DOI
  10.1016/j.biomaterials.2011.11.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23220014
[Journal Article] Dual therapy for third-line H. pylori eradication and urea breath test prediction.2012
- Author(s)
  Toshihiro Nishizawa
- Journal Title
  
  World J. Gastroenterol.
  
  Volume: 18 Pages: 2735-2738
- DOI
  10.3748/wjg.v18.i21.2735
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300169, KAKENHI-PROJECT-24659103
[Journal Article] Characterization and neural differentiation of mouse embryonic and induced pluripotent stem cells on cadherin-base substrata2012
- Author(s)
  A. Haque, X-S. Yue, A. Motazedian, Y.Tagawa, T. Akaike,
- Journal Title
  
  Biomaterials
  
  Volume: 33 Pages: 5094-5106
- DOI
  10.1016/j.biomaterials.2012.04.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23220014, KAKENHI-PLANNED-23119003
[Journal Article] Local mechanical stimulation of mardin-darby canine kidney cell sheets on temperature-responsive hydrogel.2012
- Author(s)
  Harada I, Yanagisawa S, Iwasaki K, Cho CS, Akaike T.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 13 Pages: 1095-108
- DOI
  10.3390/ijms13011095
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23220014
[Journal Article] Engulfment and clearance of apoptotic cells based on a GlcNAc-binding lectin-like property of surface vimentin.2012
- Author(s)
  Ise H, Goto M, Komura K, Akaike T.,
- Journal Title
  
  Glycobiology
  
  Volume: 22 Pages: 788-805
- DOI
  10.1093/glycob/cws052
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23220014
[Journal Article] Proton pump inhibitor-amoxicillin-clarithromycin versus proton pump inhibitor-amoxicillin-metronidazole as first-line <i>Helicobacter pylori</i> eradication therapy2012
- Author(s)
  Toshihiro Nishizawa
- Journal Title
  
  J. Clin. Biochem. Nutr.
  
  Volume: 51 Issue: 2 Pages: 114-116
- DOI
  10.3164/jcbn.d-11-00029r1
  10.3164/jcbn.D-11-00029R1
- NAID
  130004879303
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300169, KAKENHI-PROJECT-24659103
[Journal Article] Dynamic behaviors of vimentin induced by interaction with GlcNAc molecules.2012
- Author(s)
  Komura K, Ise H, Akaike T.
- Journal Title
  
  Glycobiology
  
  Volume: 22 Pages: 1741-1759
- DOI
  10.1093/glycob/cws118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23220014
[Journal Article] Feeder cells support the culture of induced pluripotent stem cells even after chemical fixation.2012
- Author(s)
  X.-S. Yue
- Journal Title
  
  PLoS One
  
  Volume: 7
- DOI
  10.1371/journal.pone.0032707
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22220009, KAKENHI-PROJECT-22500396, KAKENHI-PROJECT-23220014
[Journal Article] Cardiac differentiation of embryonic stem cells by substrate immobilization of insulin-like growth factor binding protein 4 with elastin-like polypeptides2012
- Author(s)
  Minato A, Ise H, Goto M, Akaike T
- Journal Title
  
  Biomaterials
  
  Volume: 33 Pages: 515-523
- DOI
  10.1016/j.biomaterials.2011.09.070
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23220014
[Journal Article] Control of Singular Cell Cycle Synchronization of Mouse ES Cells for Hepatocyte Differentiation on E-Cadherin Substratum2011
- Author(s)
  Jovic D., Haque A, Hexing B, Nagaoka M, Akaike T.
- Journal Title
  
  J.Biotechnol.Biomaterial 1:113 doi:10.4172/2155-952X.100011(2011)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23220014
[Journal Article] Modulation of cytochrome P450 gene expression in primary hepatocytes on various artificial extracellular matrices2011
- Author(s)
  Adachi T, Goto M, Cho CS, Akaike T
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 413 Pages: 577-581
- DOI
  10.1016/j.bbrc.2011.09.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23220014
[Journal Article] Influences of electrolytes and glucose on formulation of carbonate apatite nanocrystals for efficient gene delivery to mammalian cells2010
- Author(s)
  Hossain S, Tada S, Akaike T, Chowdhury EH
- Journal Title
  
  Anal. Biochem. 397
  
  Pages: 56-161
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200038
[Journal Article] pH-sensitive carbonate apatite as an intracellular protein transporter2010
- Author(s)
  Tada S, Chowdhury EH, Cho CS, Akaike T.
- Journal Title
  
  Biomaterials 31
  
  Pages: 1453-1459
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200038
[Journal Article] Culture of human pluripotent stem cells using completely defined conditions on a recombinant E-cadherin substratum2010
- Author(s)
  M. Nagaoka, K. Si-Tayeb, T. Akaike, and S. A. Duncan
- Journal Title
  
  BMC Dev Biol
  
  Volume: 10 Pages: 60-60
- DOI
  10.1186/1471-213x-10-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300167
[Journal Article] Vimentin and desmin possess GlcNAc-binding lectin-like properties on cell surfaces.2010
- Author(s)
  Ise H, Kobayashi S, Goto M, Sato T, Kawakubo M, Takahashi M, Ikeda U, Akaike T.
- Journal Title
  
  Glycobiology 38(In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200038
[Journal Article] An artificial extracellular matrix created by hepatocyte growth factor fused to IgG-Fc.2010
- Author(s)
  Azuma K, Nagaoka M, Cho CS, Akaike T.
- Journal Title
  
  Biomaterials 31
  
  Pages: 802-809
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200038
[Journal Article] Influences of electrolytes and glucose on formulation of carbonate apatite nanocrystals for efficient gene delivery to mammalian cells.2010
- Author(s)
  Hossain S, Tada S, Akaike T, Chowdhury EH.
- Journal Title
  
  Anal. Biochem. 397
  
  Pages: 156-161
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200038
[Journal Article] Application of Recombinant Fusion Proteins for Tissue Engineering.2010
- Author(s)
  Nagaoka M, Jiang HL, Hoshiba T., Akaike T., Cho CS.
- Journal Title
  
  Annals of Biomedical Enginering 38
  
  Pages: 683-693
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200038
[Journal Article] eprogramming of somatic cells induced by fusion of embryonic stem cells using hemagglutinating virus of Japan envelope (HVJ-E).2010
- Author(s)
  Yue XS, Fujishiro M, Toyoda M, Akaike T, Ito Y
- Journal Title
  
  Biochem Biophys Res Commun. (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200038
[Journal Article] Superparamagnetic Iron Oxide Nanoparticles Coated with Galactose-Carrying Polymer for Hepatocyte Targeting.2009
- Author(s)
  K. Yamaki, I. Harada, M. Goto, C-S. Cho, T. Akaike
- Journal Title
  
  Biomaterials 30
  
  Pages: 1421-142
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200038
[Journal Article] High performance mRNA transfection through carbonate apatite-cationic liposome conjugates2009
- Author(s)
  F.T.Zohra, E.H.Chowdhury, T.Akaike
- Journal Title
  
  Biomaterials 30
  
  Pages: 4006-4013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200038
[Journal Article] Characterization of nucleobase transport by mouse Sertoli cell line TM42009
- Author(s)
  Kato R, Maeda T, Akaike T, Tamai I.
- Journal Title
  
  Biol Pharm Bull. 32
  
  Pages: 450-455
- NAID
  110007122709
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200038
[Journal Article] Disrupting actin filaments promotes efficient transfection of a leukemia cell line using cell adhesive protein-embedded carbonate apatite particles2009
- Author(s)
  K.Kutsuzawa, S.Tada, S.Hossain, K.Fukuda, K.Maruyama, Y.Akiyama, T.Akaike, E.H.Chowdhury,
- Journal Title
  
  Anal. Biochem. 388, 164-166, (2009) 388
  
  Pages: 164-166
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200038
[Journal Article] Disrupting actin filaments promotes efficient transfection of a leukemia cell line using cell adhesive protein-embedded carbonate apatite particles Anal2009
- Author(s)
  K. Kutsuzawa, S. Tada, S. Hossain, K. Fukuda, K. Maruyama, Y. Akiyama, T. Akaike, E.H. Chowdhury
- Journal Title
  
  Biochem. 388
  
  Pages: 164-166
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200038
[Journal Article] Degradable polyethylenimines as DNA and small interfering RNA carriers.2009
- Author(s)
  Jere D, Jiang HL, Arote R, Kim YK, Choi YJ, Cho MH, Akaike T, Cho CS.
- Journal Title
  
  Expert Opin Drug Deliv.2009 6
  
  Pages: 827-834
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200038
[Journal Article] Surface coating of bone marrow cell with N-acetylglucosamine for bone marrow implantation therapy2009
- Author(s)
  S.Kobayashi, H.Ise, M.Takahasi, M.Goto, T.Akaike, U.Ikeda
- Journal Title
  
  Biomaterials 30
  
  Pages: 574-582
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200038
[Journal Article] Akaike High performance mRNA transfection through carbonate apatite-cationic liposome conjugates.2009
- Author(s)
  F.T. Zohra, E.H. Chowdhury, T. Akaike
- Journal Title
  
  Biomaterials 30
  
  Pages: 4006-4013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200038
[Journal Article] Embryonic Undifferentiated Cells Show Scattering Activity on a Surface Coated With Immobilized E-Cadherin2008
- Author(s)
  M. Nagaoka, H. Ise, I. Harada, U. Koshimizu, A. Maruyama, T. Akaike
- Journal Title
  
  J. Cell Biochem. 103
  
  Pages: 296-310
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200038
[Journal Article] Efficient transfection of mouse embryonic stem cells with cell-adhesive protein-embedded inorganic nanocarrier.2008
- Author(s)
  Kutsuzawa K, Maruyama K, Akiyama Y, Akaike T, Chowdhury EH
- Journal Title
  
  Anal Biochem 372(1)
  
  Pages: 122-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200038
[Journal Article] The influence of the cell-adhesive proteins E-cadherin and fibronectin embedded in carbonate-apatite DNA carrier on transgene delivery and expression in a mouse embryonic stem cell line2008
- Author(s)
  Kutsuzawa K, Akaike T, Chowdhury EH.
- Journal Title
  
  Biomaterials 29
  
  Pages: 370-376
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200038
[Journal Article] Embryonic Undifferentiated Cells Show Scattering Activity on a Surface Coated With Immobilized E-Cadherin.2008
- Author(s)
  Nagaoka M, Ise H, Harada I, Koshimizu U, Maruyama A, Akaike T.
- Journal Title
  
  J. Cell Biochem 103
  
  Pages: 296-310
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200038
[Journal Article] Design of the artificial acellular feeder layer for the efficient propagation of mouse ES cells.2008
- Author(s)
  Nagaoka M, Hagiwara Y, Takemura K, Murakami Y, Li J, Duncan SA, Akaike T.
- Journal Title
  
  J Biol Chem. 283
  
  Pages: 26468-26476
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200038
[Journal Article] Efficient transfection of mouse embryonic stem cells with cell-adhesive protein-embedded inorganic nanocarrier.2008
- Author(s)
  Kutsuzawa K, Maruyama K, Akiyama Y, Akaike T, Chowdhury EH
- Journal Title
  
  Anal Biochem. 372
  
  Pages: 122-124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200038
[Journal Article] Copolymers for Hepatocyte-Specific Targeting Carrying Galactose and Hydrophobic Alkyl Groups.2008
- Author(s)
  T. Hiratsuka, M. Goto, Y. Kondo, C-S. Cho, T. Akaike
- Journal Title
  
  Macromol. Biosci. 8
  
  Pages: 231-238
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200038
[Journal Article] Different regulation of hepatocyte behaviors b etween natural extracellular matrices and synthetic extracellular matrices by hepatocyte growth factor.2008
- Author(s)
  Hoshiba T, Wakejima M, Cho CS, Shiota G, Akaike T
- Journal Title
  
  J Biomed. Maere. Res. 85A
  
  Pages: 228-235
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200038
[Journal Article] Design of the artificial acellular feeder layer for the efficient propagation of mouse ES cells2008
- Author(s)
  Nagaoka M, Hagiwara Y, Takemura K, Murakami Y, Li J, Duncan SA, Akaike T
- Journal Title
  
  J Biol Chem.. 283
  
  Pages: 26468-26476
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200038
[Journal Article] Regulation of cellular morphology using temperature-responsive hydrogel for integrin-mediated mechanical force stimulation2008
- Author(s)
  Akaike, T. Hoshiba, T, Kim, S-H. Kobayashi, K. Goto, M. Jiang, H-L. Cho C-S.
- Journal Title
  
  "Tissue Engineering ; Roles, Materials and Applications" S. J. Barners and L. P. Harries Eds, Nova Science Pubishers, Inc
  
  Pages: 99-118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200038
[Journal Article] Design of Artificial Extracellular Matrices and Their Application for Regenerative Medicine.2008
- Author(s)
  Yue X., Nagaoka M., Akaike T.
- Journal Title
  
  Biomaterials in Asia
  
  Pages: 143-158
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200038
[Journal Article] The influence of the cell-adhesive proteins E-cadherin and fibronectin embedded in carbonate-apatite DNA carrier on transgene delivery and expression in a mouse embryonic stem cell line.2008
- Author(s)
  Kutsuzawa K, Akaike T, Chowdhury EH.
- Journal Title
  
  Biomaterials. 29(3)
  
  Pages: 370-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200038
[Journal Article] Embryonic undifferentiated cells show scattering activity on a surface coated with immobilized E-cadherin.2007
- Author(s)
  Nagaoka, M., Ise, H., Harada, I., Koshimizu, U., Maruyama, A.Akaike, T
- Journal Title
  
  Biochem.Biophys.Res.Commun. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15100008
[Journal Article] A simple combined floating and anchored collagen gel for enhancing mechanical strength of culture system.2007
- Author(s)
  I.Harada, T.Akaike
- Journal Title
  
  J. Biomed. Mater. Res. A. 80
  
  Pages: 123-30
- Data Source
  KAKENHI-PROJECT-15100008
[Journal Article] pH-Sensitive Inorganic Nano-Particles and Their Precise Cell Targetibility: An Efficient Gene Delivery and Expression System.2007
- Author(s)
  E.H. Chowdhury, T. Akaike
- Journal Title
  
  Current Chemical Biology 1
  
  Pages: 201-213
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200038
[Journal Article] High performance DNA nano-carriers of carbonate apatite: multiple factors in regulation of particle synthesis and transfection efficiency.2007
- Author(s)
  Chowdhury EH, Akaike T.
- Journal Title
  
  Int J Nanomedicine. 2(1)
  
  Pages: 101-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200038
[Journal Article] Epidermal growth factor signaling for matrix-dependent cell proliferation and differentiation in primary cultured hepatocyte.2007
- Author(s)
  Kim S-H., Akaike T.
- Journal Title
  
  Tissue Engineering 13
  
  Pages: 601-609
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200038
[Journal Article] 生体適合性ナノキャリアの設計とDNA・RNA・蛋白質の高効率細胞内デリバリー2007
- Author(s)
  多田誠一、E.H. Chowdhury、沓沢好一、赤池敏宏
- Journal Title
  
  再生医療 6
  
  Pages: 64-71
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200038
[Journal Article] Primary hepatocyte survival on non-integrin-recognizable matrices without the activation of Akt signaling.2007
- Author(s)
  T.Hoshiba, H.Nagahara, C-S.Cho, Y.Tagawa, T.Akaike
- Journal Title
  
  Biomaterials. 28
  
  Pages: 1093-1104
- Data Source
  KAKENHI-PROJECT-15100008
[Journal Article] pH-Sensitive Inorganic Nano-Particles and Their Precise Cell Targetibility: An Efficient Gene Delivery and Expression System.2007
- Author(s)
  E. H. Chowdhury, T. Akaike
- Journal Title
  
  Current Chemical Biology 1
  
  Pages: 201-213
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200038
[Journal Article] Primary hepatocyte survival on non-integrin-recognizable matrices without the activation of Akt signaling.2007
- Author(s)
  T.Hoshiba, H.Nagahara, C-S.Cho, Y.Tagawa, T.Akaike
- Journal Title
  
  Biomaterials 28
  
  Pages: 1093-1104
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15100008
[Journal Article] 細胞接着分子の利用による細胞制御-細胞生物学/遺伝子工学/材料工学/物理学間の学際的融合による細胞認識材料設計とその再生医療への応用2007
- Author(s)
  赤池敏宏、長岡正人、E.H. Chowdhoury、原田伊知郎
- Journal Title
  
  材料の科学と工学 44(1)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200038
[Journal Article] Effective delivery with enhanced translation activity synergistically accelerates mRNA-based transfection.2007
- Author(s)
  F.T. Zohra, E.H. Chowdhoury, S. Tada, T. Hoshiba, T. Akaike
- Journal Title
  
  Biochem. Biophys. Res. Commun. 358
  
  Pages: 373-378
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19200038
[Journal Article] A simple combined floating and anchored collagen gel for enhancing mechanical strength of culture system.2007
- Author(s)
  I.Harada, T.Akaike
- Journal Title
  
  J. Biomed. Mater. Res. 80
  
  Pages: 123-130
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15100008
[Journal Article] Embryonic undifferentiated cells show scattering activity on a surface coated with immobilized E-cadherin.2007
- Author(s)
  Nagaoka, M., Ise, H., Harada, I., Koshimizu, U., Maruyama, A., Akaike, T
- Journal Title
  
  Biochem. Biophys. Res. Commun. (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15100008
[Journal Article] Primary hepatocyte survival on non-integrin-recognizable matrices without the activation of Akt signaling.2007
- Author(s)
  T.Hoshiba, H.Nagahara, C-S.Cho, Y.Tagawa, T.Akaike
- Journal Title
  
  Biomaterials. 28
  
  Pages: 1093-1104
- Data Source
  KAKENHI-PROJECT-17655074
[Journal Article] A simple combined floating and anchored collagen gel for enhancing mechanical strength of culture system.2007
- Author(s)
  I.Harada, T.Akaike
- Journal Title
  
  J. Biomed. Mater. Res. A. 80
  
  Pages: 123-130
- Data Source
  KAKENHI-PROJECT-17655074
[Journal Article] A simple combined floating and anchored collagen gel for enhancing mechanical strength of culture system.2007
- Author(s)
  I.Harada, Kim SG, Cho CS, Kurosawa K, T.Akaike
- Journal Title
  
  J.Biomed.Mater.Res. 80
  
  Pages: 123-30
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15100008
[Journal Article] Effect of photo-immobilization of epidermal growth factor on the cellular behaviors.2006
- Author(s)
  K.Ogiwara, M.Nagaoka, C-S.Cho, T.Akaike
- Journal Title
  
  Biochem.Biophys.Res.Commun. 345
  
  Pages: 255-259
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15100008
[Journal Article] E-cadherin-coated plates maintain pluripotent ES cells without colony formation.2006
- Author(s)
  M.Nagaoka, U.Koshimizu, S.Yuasa, F.Hattori, H.Chen, T.Tanaka, M.Okabe, K.Fukuda, T.Akaike
- Journal Title
  
  PLoS ONE 1
- Data Source
  KAKENHI-PROJECT-17655074
[Journal Article] Effect of photo-immobilization of epidermal growth factor on the cellular behaviors.2006
- Author(s)
  K.Ogiwara, M.Nagaoka, C-S.Cho, T.Akaike
- Journal Title
  
  Biochem. Biophys. Res. Commun. 345
  
  Pages: 255-259
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15100008
[Journal Article] Surface functionalization of inorganic nano-crystals with fibronectin and E-cadherin chimera synergistically accelerates trans-gene delivery into embryonic stem cells.2006
- Author(s)
  K.Kutsuzawa, E.H.Chowdhury, M.Nagaoka, K.Maruyama, Y.Akiyama, T.Akaike
- Journal Title
  
  Biochem. Biophys. Res. Commun. 350
  
  Pages: 514-520
- Data Source
  KAKENHI-PROJECT-15100008
[Journal Article] Effect of photo-immobilization of epidermal growth factor on the cellular behaviors.2006
- Author(s)
  K.Ogiwara, M.Nagaoka, C-S.Cho, T.Akaike
- Journal Title
  
  Biochem. Biophys. Res. Commun. 345
  
  Pages: 255-259
- Data Source
  KAKENHI-PROJECT-17655074
[Journal Article] A simple combined floating and anchored collagen gel for enhancing mechanical strength of culture system.2006
- Author(s)
  I.Harada, SG.Kim, CS.Cho, H.Kurosawa, T.Akaike
- Journal Title
  
  J. Bio. Mater. Res. Part A 19(3)
  
  Pages: 419-424
- Data Source
  KAKENHI-PROJECT-17651084
[Journal Article] Epidermal growth factor signaling for matrix-dependent cell proliferation and differentiation in primary cultured hepatocyte.2006
- Author(s)
  S-H.Kim, T.Akaike
- Journal Title
  
  Tissue Engineering 13
  
  Pages: 601-609
- Data Source
  KAKENHI-PROJECT-15100008
[Journal Article] Surface functionalization of inorganic nano-crystals with fibronectin and E-cadherin chimera synergistically accelerates trans-gene delivery into embryonic stem cells.2006
- Author(s)
  K.Kutsuzawa, E.H.Chowdhury, M.Nagaoka, K.Maruyama, Y.Akiyama, T.Akaike
- Journal Title
  
  Biochem. Biophys. Res. Commun. 350
  
  Pages: 514-520
- Data Source
  KAKENHI-PROJECT-17655074
[Journal Article] Galactose-carying polymers as extracellular matrices for liver tissue engineering2006
- Author(s)
  CS.Cho, SJ.Seo, IK.Park, SH.Kim, TH.Kim, T.Hoshiba, I.Harada, T.Akaike
- Journal Title
  
  Biomaterials 27(4)
  
  Pages: 576-585
- Data Source
  KAKENHI-PROJECT-17651084
[Journal Article] E-cadherin-coated plates maintain pluripotent ES cells without colony formation.2006
- Author(s)
  M.Nagaoka, U.Koshimizu, S.Yuasa, F.Hattori, H.Chen, T.Tanaka, M.Okabe, K.Fukuda, T.Akaike
- Journal Title
  
  PLoS ONE 1
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15100008
[Journal Article] Epidermal growth factor signaling for matrix-dependent cell proliferation and differentiation in primary cultured hepatocyte.2006
- Author(s)
  S-H.Kim, T.Akaike
- Journal Title
  
  Tissue Engineering 13
  
  Pages: 601-609
- Data Source
  KAKENHI-PROJECT-17655074
[Journal Article] E-cadherin-coated plates maintain pluripotent ES cells without colony formation.2006
- Author(s)
  M.Nagaoka, U.Koshimizu, S.Yuasa, F.Hattori, H.Chen, T.Tanaka, M.Okabe, K.Fukuda, T.Akaike
- Journal Title
  
  PLoS ONE 1,
- Data Source
  KAKENHI-PROJECT-15100008
[Journal Article] Adsorption behaviors of poly(N-p-vinylbenzyl-4-o-b-d-galactopyranosyl-[1→4]-d-gluconamide) by quartz-crystal microbalance.2005
- Author(s)
  Takei R., Seo S.J., Cho C.S, Okahata Y., Akaike T.
- Journal Title
  
  Colloids and Surfaces B : Biointerfaces, 42
  
  Pages: 137-140
- Data Source
  KAKENHI-PROJECT-15100008
[Journal Article] Fabrication of elastic substrates for tissue engineering by two-photon initiated polymerization2005
- Author(s)
  N.Kimura, K.Totani, T.Watanabe, I.Harada, A.Oguni, T.Akaike
- Journal Title
  
  Nonlinear Opt.Quantum Opt. 34
  
  Pages: 203-206
- Data Source
  KAKENHI-PROJECT-17651084
[Journal Article] Mammalian integrin-targeted gene delivery : A common approach for advanced viral and non-viral vectors.2005
- Author(s)
  Chowdhury E.H., Akaike T.
- Journal Title
  
  Gene.Ther.Mol.Biol. 9
  
  Pages: 431-444
- Data Source
  KAKENHI-PROJECT-15100008
[Journal Article] Fabrication of elastic substrates for tissue engineering by two-photon initiated polymerization2005
- Author(s)
  Kimura N., Watanabe T., Totani K., Oguni A., Harada I., Akaike T.
- Journal Title
  
  Nonlinear Optics, Quantum Optics 34
  
  Pages: 203-206
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15100008
[Journal Article] A Bio-Recognition Device Developed Onto Nano-Crystals of Carbonate Apatite for Cell-Targeted Gene Delivery.2005
- Author(s)
  Chowdhury E.H., Akaike T.
- Journal Title
  
  Biotechnology and Bioengineering 90
  
  Pages: 414-419
- Data Source
  KAKENHI-PROJECT-15100008
[Journal Article] Hepatocyte Adhesion on a Poly [N-p-vinylbenzyl-4-O-b-D-galactopyranosyl-D-glucoamide]-Coated Poly(L-lactic acid )Surface.2005
- Author(s)
  Lee J.S., Kim S.H., Kim Y.J., Akaike T., Kim S.C
- Journal Title
  
  Biomacromolecules 6
  
  Pages: 1906-1911
- Data Source
  KAKENHI-PROJECT-15100008
[Journal Article] Advances in Fabrication of Calcium Phosphate Nano-composites for Smart Delivery of DNA and RNA to Mammalian Cells.2005
- Author(s)
  Chowdhury E.H., Akaike T.
- Journal Title
  
  Current Analytical Chemistry 1
  
  Pages: 187-192
- Data Source
  KAKENHI-PROJECT-17655074
[Journal Article] ES細胞から肝臓の発生・再構築を目指して、その薬理学的応用2005
- Author(s)
  田川陽一, 赤池敏宏
- Journal Title
  
  Pharm Tech Japan, 21
  
  Pages: 2051-2054
- Data Source
  KAKENHI-PROJECT-17655074
[Journal Article] Construction of a novel extracellular matrix using a new genetically engineered epidermal growth factor fused to IgG-Fc.2005
- Author(s)
  Ogiwara K., Nagaoka M., Cho C-S., Akaike T.
- Journal Title
  
  Biotechnology Letters, 27
  
  Pages: 1633-1637
- Data Source
  KAKENHI-PROJECT-17655074
[Journal Article] Role of E-cadherin molcules in speroid formation of hepatocytes adhered on galactose-carring polymer as an artificial asialoglycoprotein model2005
- Author(s)
  Takei R., Suzuki D., Hoshiba T., Nagaoka M., Seo S.J., Cho C.S., Akaike T.
- Journal Title
  
  Biotechnology Letters 27
  
  Pages: 1149-1156
- Data Source
  KAKENHI-PROJECT-17655074
[Journal Article] Hepatocyte behavior on synthetic glycopolymer matrix : inhibitory effect of receptor-ligand binding on hepatocyte spreading.2005
- Author(s)
  S-H.Kim, T.Hoshiba, T.Akaike
- Journal Title
  
  Biomaterials 25
  
  Pages: 1813-1823
- Data Source
  KAKENHI-PROJECT-15100008
[Journal Article] Albumin and urea production by hepatocytes cultured on extracellular matrix proteins-conjugated poly(vinyl alcohol) membranes2005
- Author(s)
  Higuchi A., Kurihara M., Kobayashi K., Cho C-S., Akaike T., Hara
- Journal Title
  
  J.Biomater.Sci.Polymer Edn. 16
  
  Pages: 847-860
- Data Source
  KAKENHI-PROJECT-15100008
[Journal Article] Fabrication of Elastic Substrates for Tissue Engineering by Two-photon Initiated Polymerization2005
- Author(s)
  T.Watanabe, N.Kimura, K.Totani, I.Harada, T.Akaike
- Journal Title
  
  Nonlinear Opt. (In press)
- Data Source
  KAKENHI-PROJECT-15651069
[Journal Article] Integrin-Supported Fast Rate Intracellular Delivery of Plasmid DNA by Extracellular Matrix Protein Embedded Calcium Phosphate Complexes,2005
- Author(s)
  Chowdhury E.H., Nagaoka M., Ogiwara K., Zohra F.T., Kutsuzawa K., Tada S., Kitamura C., Akaike T.
- Journal Title
  
  Biochemistry 44
  
  Pages: 12273-12278
- Data Source
  KAKENHI-PROJECT-17655074
[Journal Article] Drastic effect of nanoapatite particles on liposome-mediated mRNA delivery to mammalian cells.2005
- Author(s)
  Zohra F.T., Chowdhury E.H., Nagaoka M., Akaike T.
- Journal Title
  
  Analytical Biochemistry 345
  
  Pages: 164-166
- Data Source
  KAKENHI-PROJECT-17655074
[Journal Article] Fabrication of Elastic Substrates for Tissue Engineering by Two-Photon Initiated Polymerization.2005
- Author(s)
  Kimura T, Watanabe T, Totani K, Oguni A, Harada I, Akaike T.
- Journal Title
  
  Nonlinear Optics, Quantum Optics. 34
  
  Pages: 203-206
- Data Source
  KAKENHI-PROJECT-15100008
[Journal Article] High-efficiency gene delivery for expression in mammalian cells by nanoprecipitates of Ca-Mg phosphate.2004
- Author(s)
  E.H.Chowdhury, M.Kunou, M.Nagaoka, A.K.Kundu, T.Hoshiba, T.Akaike
- Journal Title
  
  Gene 341
  
  Pages: 77-82
- Data Source
  KAKENHI-PROJECT-15100008
[Journal Article] Xyloglucan as a synthetic extracellular matrix for hepatocyte attachment.2004
- Author(s)
  S.J.Seo, I-K.Park, M-K.Yoo, M.Shirakawa, T.Akaike, C.S.Cho
- Journal Title
  
  J.Biomater.Sci.Polymer Edn. 15
  
  Pages: 1375-1387
- Data Source
  KAKENHI-PROJECT-15100008
[Journal Article] Effective Hepatocyte Transplantation Using Rat Hepatocytes with Low Asialoglycoprotein Receptor Expression.2004
- Author(s)
  H.Ise, T.Nikaido, N.Negishi, N.Sugihara, F.Suzuki, T.Akaike, U.Ikeda
- Journal Title
  
  Am.J.Pathol. 165
  
  Pages: 501-510
- Data Source
  KAKENHI-PROJECT-15100008
[Patent] 組織撮影用MRI造影剤2009
- Inventor(s)
  赤池敏宏、篠田さやか、後藤光昭
- Industrial Property Rights Holder
  東京工業大学・セラジックス
- Filing Date
  2009-03-09
- Data Source
  KAKENHI-PROJECT-19200038
[Patent] 細胞培養用基材2008
- Inventor(s)
  佐竹真、福井三由紀、兼子博章、赤池敏宏、賀喜白乙
- Industrial Property Rights Holder
  帝人株式会社、東京工業大学
- Filing Date
  2008-09-11
- Data Source
  KAKENHI-PROJECT-19200038
[Patent] 細胞培養用基材2008
- Inventor(s)
  佐竹真, 赤池敏宏, 外
- Industrial Property Rights Holder
  帝人株式会社, 国立大学法人東京工業大学
- Industrial Property Number
  2008-233322
- Filing Date
  2008-09-11
- Data Source
  KAKENHI-PROJECT-19200038
[Patent] 物質導入担体、物質導入方法及び物質導入用キット2005
- Inventor(s)
  赤池敏宏, Choudhury Fatema
- Industrial Property Rights Holder
  東京工業大学
- Filing Date
  2005-08-31
- Data Source
  KAKENHI-PROJECT-15100008
[Presentation] カドヘリンマトリックス工学を応用した再生医療2018
- Author(s)
  赤池　敏宏
- Organizer
  第56回日本人工臓器学会大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02104
[Presentation] 高分子バイオマテリアル研究の歴史と未来-細胞認識性と非認識性は表裏一体である-2018
- Author(s)
  赤池　敏宏
- Organizer
  鶴田・赤池フォーラム in 九大
- Invited
- Data Source
  KAKENHI-PROJECT-17H02104
[Presentation] 細胞認識性バイオマテリアル設計によるES細胞からバイオ人工肝臓へのチャレンジ2018
- Author(s)
  赤池　敏宏
- Organizer
  第56回日本人工臓器学会大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02104
[Presentation] Cadherin-Matrix Engineering in Cell-Recognizable Biomaterials2018
- Author(s)
  赤池　敏宏
- Organizer
  Chain-Japan Joint Symposium on Biomaterials 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02104
[Presentation] Cadherin-Matrix Engineering for Control of ES/iPS Cells Proliferation and Differentiation2018
- Author(s)
  赤池　敏宏
- Organizer
  The 5th International Biomaterials Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H02104
[Presentation] Cadherin-Matrix Engineering in Cell-Recognizable Biomaterials2014
- Author(s)
  Toshihiro Akaike
- Organizer
  9th TOIN International Symposium BME
- Place of Presentation
  Yokohama
- Year and Date
  2014-11-08
- Invited
- Data Source
  KAKENHI-PROJECT-23220014
[Presentation] Adrenomedullin 1-based novel cell-recognizable biomaterial for stem cell technology2013
- Author(s)
  Nag K. Akaike T.
- Organizer
  4th Asian Biomaterial Symposium
- Place of Presentation
  Hong Kong, China
- Data Source
  KAKENHI-PROJECT-23220014
[Presentation] N-cadherin Assisted Induction of Neuronal Lineage Differentiation of Embryonic and Induced Pluripotent Stem Cells2013
- Author(s)
  Adnan　N. , Kutsuzawa K., Haque A. Akaike T.
- Organizer
  The 4th Asian Biomaterials Congres
- Place of Presentation
  Hong Kong, China
- Data Source
  KAKENHI-PROJECT-23220014
[Presentation] 細胞骨格分子ビメンチンの細胞表面への出現とN-アセチルグルコサミン結合活性に基づく生理的意義の解明2013
- Author(s)
  伊勢裕彦、赤池敏宏
- Organizer
  第65回日本細胞生物学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23220014
[Presentation] Adrenomedullin 1-based novel cell recognizable biomaterial: exploring the role in regenerative medicine and tissue engineering2013
- Author(s)
  Nag K. Akaike T.
- Organizer
  ISCCR annual meeting
- Place of Presentation
  Boston USA
- Data Source
  KAKENHI-PROJECT-23220014
[Presentation] Efficient Production and Purification of NCad-Fc-chimeric Protein-based Biomaterials for Application in Tissue-engineering and Regenerative medicine2013
- Author(s)
  Kutsuzawa K., Nag K., Nagaoka M., Akaike T.
- Organizer
  TERMIS-AP 2013 Annual Conference
- Place of Presentation
  Shanghai-Wuzhen, China
- Data Source
  KAKENHI-PROJECT-23220014
[Presentation] 糖鎖高分子を用いた細胞骨格分子ビメンチンの細胞豹変の出現とN-アセチルグルコサミン結合活性に基づく生理的意義の解明2013
- Author(s)
  伊勢裕彦、赤池敏宏
- Organizer
  第36回　日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23220014
[Presentation] Fc Chimeric Protein-based Biomaterials: Advancing Stem Cell Technology and Regenerative Medicine Toward Application2013
- Author(s)
  Nag K., Kutsuzawa K., Nagaoka M.,Yang J., Akaike T.
- Organizer
  TERMIS-AP 2013 Annual Conference
- Place of Presentation
  Shanghai-Wuzhen, China
- Data Source
  KAKENHI-PROJECT-23220014
[Presentation] 糖鎖高分子を用いた細胞骨格分子ビメンチンの細胞豹変の出現とN-アセチルグルコサミン結合活性に基づく生理的意義の解明2013
- Author(s)
  伊勢裕彦、赤池敏宏
- Organizer
  第86回　日本生化学大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23220014
[Presentation] Artificial Extracellular Matrix as an Advanced Stem Cell Microenviron ment for Regenerative Medicine and Tissue Engineering-Novel Approach of Cell Cooking Plate-2011
- Author(s)
  T.Akaike
- Organizer
  the 11th Asian BioCeramics Symposium (ABC2011)
- Place of Presentation
  筑波(招待講演)
- Year and Date
  2011-11-30
- Data Source
  KAKENHI-PROJECT-23220014
[Presentation] Characterization of Artificial Liver Tissues Composed of Primary Hepatocytes Embedded in Dense Collagen Gels2011
- Author(s)
  Tamai Miho Akaike T., Adachi E., Tagawa Y.
- Organizer
  Gordon Research Conference on Collagen
- Place of Presentation
  New London
- Data Source
  KAKENHI-PROJECT-22300167
[Presentation] 培養皿固定型心筋分化誘導因子を用いた胚性幹(ES)細胞の効率的心筋分化誘導法の確立2011
- Author(s)
  湊彩や香, 赤池敏宏
- Organizer
  第33回日本バイオマテリアル学会
- Place of Presentation
  京都
- Year and Date
  2011-11-21
- Data Source
  KAKENHI-PROJECT-23220014
[Presentation] Design of Cell-recognizable Nanobiomaterials for ES/iPS Cells Proliferati on and Hepatocyte Differentiation-Concept of Cell Cooking Plate for Regenerative Engineering-2011
- Author(s)
  T.Akaike
- Organizer
  The 3rd Asian Biomaterials Congress
- Place of Presentation
  Busan Korea(招待講演)
- Year and Date
  2011-09-15
- Data Source
  KAKENHI-PROJECT-23220014
[Presentation] Proliferation of cdx2-expressing human esophageal cells is enhanced by bile acid with upregulation.2011
- Author(s)
  Matsuzaki, J., Suzuki, H., Saito, Y., and Akaike, T., et al.
- Organizer
  UEGW2011
- Place of Presentation
  Stockholm, Sweden
- Year and Date
  2011-10-25
- Data Source
  KAKENHI-PROJECT-22300169
[Presentation] Efficient differentiation of ESCs to cardiomyocyte on thermoresponsive IGFBP4-chimeric protein2011
- Author(s)
  A.Minato, H.Ise, T.Akaike
- Organizer
  The 3rd Asian Biomaterials Congress
- Place of Presentation
  Busan Korea
- Year and Date
  2011-09-15
- Data Source
  KAKENHI-PROJECT-23220014
[Presentation] 再生医療革新に果たすバイオマテリアル研究の役割-ES/iPS細胞用まな板(Cooking-plate)の設計2011
- Author(s)
  赤池敏宏
- Organizer
  第40回医用高分子シンポジウム
- Place of Presentation
  大阪
- Year and Date
  2011-07-26
- Data Source
  KAKENHI-PROJECT-23220014
[Presentation] Differentiation of neural cells from mouse embryonic or induced pluripotent stem cells using completely defined conditions on cadherin-based 'Cell-Cooking Plate'2011
- Author(s)
  A.Haque, XS Yue, T Akaike
- Organizer
  Stem Cells in the Development and Disease
- Place of Presentation
  Berlin, Germany
- Year and Date
  2011-09-11
- Data Source
  KAKENHI-PROJECT-23220014
[Presentation] Biomaterials Design for ES/iPS Cells Engineering in Regenerative Medicine2010
- Author(s)
  Toshihiro Akaike
- Organizer
  APMT2010 Advanced Polymeric Materials and Technology Symposium (APMT 2010),
- Place of Presentation
  The Shilla Jeju, Korea
- Year and Date
  2010-01-25
- Data Source
  KAKENHI-PROJECT-19200038
[Presentation] E-カドヘリン-Fcキメラ抗体を用いたES細胞から肝細胞への高効率分化誘導2010
- Author(s)
  赤池敏宏
- Organizer
  第9回日本再生医療学会総会
- Place of Presentation
  広島国際会議場
- Year and Date
  2010-03-19
- Data Source
  KAKENHI-PROJECT-19200038
[Presentation] 増殖性肝前駆様細胞を用いた高密度コラーゲンゲルによる3次元肝組織化2010
- Author(s)
  玉井美保、赤池敏宏、安達栄治郎、田川陽一他2名
- Organizer
  第32回日本バイオマテリアル学会大会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-22300167
[Presentation] New frontier of nanobiomaterials design for stem cell technology and regenerative medicine2009
- Author(s)
  Toshihiro Akaike
- Organizer
  The 2nd Annual Congress of Regenerative Medicine & Stem Cell
- Place of Presentation
  Dalian, China
- Year and Date
  2009-08-08
- Data Source
  KAKENHI-PROJECT-19200038
[Presentation] Design of Cell-recognition Biomaterials for Regenerative medicine and Cell-Targeting Medicine2009
- Author(s)
  Toshihiro Akaike
- Organizer
  2009 International Symposium on Crystal Engineering & Drug Delivery System
- Place of Presentation
  Tianjin, China
- Year and Date
  2009-09-06
- Data Source
  KAKENHI-PROJECT-19200038
[Presentation] New frontier of nanobiomaterials design for stem cell technology and regenerative medicine2009
- Author(s)
  Toshihiro Akaike
- Organizer
  2nd TERMIS World Congress in conjunction with 2009 Seoul Stem Cell Symposium
- Place of Presentation
  Seoul, Korea
- Year and Date
  2009-09-03
- Data Source
  KAKENHI-PROJECT-19200038
[Presentation] New Fontier of Nanobiomaterials for Regenerative Medicine2009
- Author(s)
  赤池敏宏
- Organizer
  China-Jpan Bio-forum of RegenerativeMedicine and Related Technoloy
- Place of Presentation
  上海
- Year and Date
  2009-03-18
- Data Source
  KAKENHI-PROJECT-19200038
[Presentation] 細胞間接着分子のモデルタンパク質E-cad-FcによるES/iPS細胞の新しい培養システムの開発2009
- Author(s)
  赤池敏宏
- Organizer
  第31回日本バイオマテリアル学会大会
- Place of Presentation
  京都テルサ
- Year and Date
  2009-11-17
- Data Source
  KAKENHI-PROJECT-19200038
[Presentation] Design of cell-specific glycopolymers and chimeric proteins for regenerative me dicine2009
- Author(s)
  Toshihiro Akaike
- Organizer
  Biomaterials Asia 2009
- Place of Presentation
  Hong Kong
- Year and Date
  2009-04-07
- Data Source
  KAKENHI-PROJECT-19200038
[Presentation] Cell Recogonizable Bionanomaterials for ES/iPS Cells Engineering in Regenerative Medicine2009
- Author(s)
  Toshihiro Akaike
- Organizer
  (AEARU) 10th Workshop on Molecular Biology and Biotechnology organized for Association of East Asian Research Universities
- Place of Presentation
  Taiwan
- Year and Date
  2009-11-12
- Data Source
  KAKENHI-PROJECT-19200038
[Presentation] Design of Cell-recognition Biomaterials for Regenerative medicine and Cell-Targeting Medicine.2009
- Author(s)
  T. Akaike
- Organizer
  2009 International Symposium on Crystal Engineering & Drug Delivery System
- Place of Presentation
  Tianjin, China
- Year and Date
  2009-08-06
- Data Source
  KAKENHI-PROJECT-19200038
[Presentation] Biomaterials Design for ES/iPS Cells Engineering in Regenerative Medicine2009
- Author(s)
  Toshihiro Akaike
- Organizer
  CTS-JSOPMB Joint Conference(国際細胞移植会議)
- Place of Presentation
  岡山コンベンションセンター
- Year and Date
  2009-04-21
- Data Source
  KAKENHI-PROJECT-19200038
[Presentation] Design of Biomimetic Glycopolymers and Chimeric Proteins for Regenerative Medicine2009
- Author(s)
  Toshihiro Akaike
- Organizer
  The 1st FAPS Polymer Congres
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-19200038
[Presentation] Design of Biomimetic Glycopolymers and Chimeric Proteins for Regenerative Medicine2009
- Author(s)
  Toshihiro Akaike
- Organizer
  2009 Asia Conference for Biomaterials & Stem Cell Techniques
- Place of Presentation
  Taipei Taiwan
- Year and Date
  2009-09-21
- Data Source
  KAKENHI-PROJECT-19200038
[Presentation] Intracellular Protein Delivery by Carbonate Apatite Carrier2008
- Author(s)
  S. Tada, E. H. Chowdhury, H. Chen, T. Akaike
- Organizer
  8^<th> World Biomaterial Congress
- Place of Presentation
  Amsterdam
- Year and Date
  2008-05-28
- Data Source
  KAKENHI-PROJECT-19200038
[Presentation] Design of a smart delivery system for anti cancer drugs based on inorganic nanocrystals of carbonate apatite2008
- Author(s)
  S. Hossain, E. H. Chowdhury, T. Akaike
- Organizer
  8^<th> World Biomaterial Congress
- Place of Presentation
  Amsterdam
- Year and Date
  2008-05-28
- Data Source
  KAKENHI-PROJECT-19200038
[Presentation] 細胞認識機能性バイオマテリアルの新展開2008
- Author(s)
  赤池敏宏
- Organizer
  日本バイオマテリアル学会シンポジウム2008
- Place of Presentation
  東京大学
- Year and Date
  2008-11-17
- Data Source
  KAKENHI-PROJECT-19200038
[Presentation] 細胞認識機能性バイオマテリアルの新展開2008
- Author(s)
  Akaike, T.
- Organizer
  (2008 TERMIS-AP)2008 Annual Conference of Tissue Engineering and Regenerative Medicine International Society - Asian Pacific Region
- Place of Presentation
  台北
- Year and Date
  2008-11-17
- Data Source
  KAKENHI-PROJECT-19200038
[Presentation] Design of Intracellular Protein Delivery System by Carbonate Apatite Carrier2008
- Author(s)
  S. Tada, E. H. Chowdhury, H. Chen, T. Akaike
- Organizer
  35th Annual Meeting & Exposition of the Controlled Release Society
- Place of Presentation
  New York
- Year and Date
  2008-07-15
- Data Source
  KAKENHI-PROJECT-19200038
[Presentation] Design of an Efficient pH Sensitive Delivery System for Anti cancer Drugs Based on Inorganic Nanocrystals of Carbonate Apatite2008
- Author(s)
  S. Hossain, E. H. Chowdhury, T. Akaike
- Organizer
  35th Annual Meeting & Exposition of the Controlled Release Society
- Place of Presentation
  New York
- Year and Date
  2008-07-15
- Data Source
  KAKENHI-PROJECT-19200038
[Presentation] New Biocompatible Nano-carriers System for Targeted DNA/Drug Delivery and Regenerative Medicine2008
- Author(s)
  Akaike, T.
- Organizer
  2008 KCRS Annual Conference
- Place of Presentation
  Chejudo Korea
- Year and Date
  2008-09-04
- Data Source
  KAKENHI-PROJECT-19200038
[Presentation] Design of Biomimetic Glycopolymers and Chimeric Proteins for Regenerative Medicine2008
- Author(s)
  Akaike, T.
- Organizer
  42nd World Polymer Congress
- Place of Presentation
  Taipei
- Year and Date
  2008-07-02
- Data Source
  KAKENHI-PROJECT-19200038
[Presentation] 生体異物反応と適合性2008
- Author(s)
  赤池敏宏
- Organizer
  ナノ粒子研究会第44回公開講演会
- Place of Presentation
  御茶ノ水
- Year and Date
  2008-09-26
- Data Source
  KAKENHI-PROJECT-19200038
[Presentation] 第4章セラミックス2.炭酸アパタイト生理活性分子の導入キャリアとしての炭酸アパタイトナノ粒子2007
- Author(s)
  多田誠一・E.H. Chowdhury・沓沢好一・赤池敏宏
- Organizer
  遺伝子医学MOOK別冊絵で見てわかるナノDDSマテリアルから見た治療・診断・予後・予防、ヘルスケア技術の最先端
- Data Source
  KAKENHI-PROJECT-19200038
[Presentation] Cell-recognizable Matrix-Engineering for Regenerative Medicine2007
- Author(s)
  T. Akaike
- Organizer
  BIO KOREA 2007
- Place of Presentation
  COEX SEOUL
- Year and Date
  2007-09-14
- Data Source
  KAKENHI-PROJECT-19200038
[Presentation] Self-renewal and differentiation of ES and iPS cells on bioengineered surfaces: novel approach of Cell-Cooking Plate
- Author(s)
  Akaike T.
- Organizer
  International Conference on Regenerative Biomedical Materials ICRBM 2013
- Place of Presentation
  Wuhan、China
- Invited
- Data Source
  KAKENHI-PROJECT-23220014
[Presentation] 炭酸アパタイトナノ粒子の再生医療への応用－ES細胞用まな板としてのEカドヘリンFcの効果－
- Author(s)
  赤池敏宏, 沓沢好一, Hossain Md. Sharif,
- Organizer
  日本バイオマテリアル学会シンポジウム2012
- Place of Presentation
  仙台国際センター（宮城県）
- Invited
- Data Source
  KAKENHI-PROJECT-23220014
[Presentation] 肝細胞認識マトリックスを用いたES細胞から肝細胞への分化とソーティングの促進
- Author(s)
  孟慶圓、Haque Md. Amranul1、赤池敏宏
- Organizer
  第19回肝細胞研究会
- Place of Presentation
  札幌医科大学（北海道）
- Data Source
  KAKENHI-PROJECT-23220014
[Presentation] Development of liver cell culture system using galactose- and N-acetylglucodsamine-bearing polymers,
- Author(s)
  Ise H, Kim SJ, and Akaike T.
- Organizer
  2nd International Conference on Biomaterials Science in Tsukuba (ICBS2013)
- Place of Presentation
  つくば国際会議場（茨城県）
- Data Source
  KAKENHI-PROJECT-23220014
[Presentation] ES/iPS用まな板(Cooking-Plate）の設計による肝細胞分化の高効率誘導と肝組織化
- Author(s)
  赤池敏宏
- Organizer
  第11回日本再生医療学会総会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Invited
- Data Source
  KAKENHI-PROJECT-23220014
[Presentation] Cadherin-Matrix Engineering for new frontier of Cell Recognition Biomaterials
- Author(s)
  Toshihiro Akaike
- Organizer
  7Th World Congress on Preventive and Regenerative Medicine (WCPRM2014)
- Place of Presentation
  Chientan Youth Activity Center,Taipei,Taiwan
- Year and Date
  2014-11-04 – 2014-11-07
- Invited
- Data Source
  KAKENHI-PROJECT-23220014
[Presentation] SUPER EFFECTIVE CAPATITE NANOPARTICLES AS A VERSETILE TOOL FOR GENE BASED NANO-MEDICINE DELIVERY
- Author(s)
  Toshihiro Akaike
- Organizer
  The 2nd International Symposium on Polymer Ecomaterials
- Place of Presentation
  Kunming,Chaina
- Year and Date
  2014-08-22 – 2014-08-26
- Invited
- Data Source
  KAKENHI-PROJECT-23220014
[Presentation] Design of Cell-recognizable Nano-biomaterials for ES/iPS Cell Proliferation and Differentiation －Cadherin-based "Cell-Cooking Plate"－
- Author(s)
  T. Akaike, M. A. Haque
- Organizer
  TOIN International Symposium on Biomedical Engineering 2012
- Place of Presentation
  桐蔭大学（神奈川県）
- Invited
- Data Source
  KAKENHI-PROJECT-23220014
[Presentation] 幹細胞培養工学における細胞認識性バイオマテリアル設計の重要性
- Author(s)
  赤池敏宏
- Organizer
  第13回日本再生医療学会総会
- Place of Presentation
  京都
- Invited
- Data Source
  KAKENHI-PROJECT-23220014
[Presentation] ntracellular Regulation of ES/iPS Cells on E-Cad-Fc Engineered Matrix facilitated by Bio-functionalized Nanoparticles of Carbonate Apatite.
- Author(s)
  S. Hossain and T. Akaike,
- Organizer
  3rd TERMIS World Congress　2012
- Place of Presentation
  Vienｎa, Austria
- Data Source
  KAKENHI-PROJECT-23220014
[Presentation] 細胞認識性マトリックスによる肝細胞の膜極性と薬物代謝機能の制御
- Author(s)
  足立達彦、赤池敏宏
- Organizer
  第19回肝細胞研究会
- Place of Presentation
  札幌医科大学（北海道）
- Data Source
  KAKENHI-PROJECT-23220014
[Presentation] Synergistic enhanced differentiation of mouse embryonic stem cells to hepatocytes using hybrid extracellular matrix composed of fusion proteins.
- Author(s)
  Qingyuan Meng, Toshihiro Akaike,
- Organizer
  ISSCR (International Society for Stem Cell Research) 2012 Annual Meeting
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-23220014
[Presentation] Cadherin-based Biomaterials forDifferentiation of Neural Cells from ES and iPS Cells underFeeder-/Serum-free Homogenious CultureSystem.
- Author(s)
  Amranul Haque, Xiao-ShanYue, Toshihiro Akaike
- Organizer
  9th World Biomaterials Congress,
- Place of Presentation
  Chengdu ,China
- Data Source
  KAKENHI-PROJECT-23220014
[Presentation] Super Effective pH-sensitive carbonate apatite for intracellular regulation of cancer,ES/iPS cells:Advancing nanobiomarerial research towards biomedical engineering
- Author(s)
  Sharif Hossain,Toshihiro Akaike
- Organizer
  第10回国際高分子カンファランス〔The10th　IPC2014)
- Place of Presentation
  つくば国際会議場
- Year and Date
  2014-12-02 – 2014-12-05
- Data Source
  KAKENHI-PROJECT-23220014
[Presentation] Design of Cell Recognition Biomaterials and Prospect for Development of Cadherin-Marices Engineering
- Author(s)
  Toshihiro Akaike, A. Haque, M. Nagaoka and Jun Yang
- Organizer
  2nd International Conference on Biomaterials Science in Tsukuba (ICBS2013)
- Place of Presentation
  つくば国際会議場（茨城県）
- Invited
- Data Source
  KAKENHI-PROJECT-23220014
[Presentation] 細胞認識性ナノバイオマテリアル設計論としてのカドヘリンマトリックス工学
- Author(s)
  赤池敏宏
- Organizer
  高分子テクノロジー研究会
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-23220014
[Presentation] Cell-recognizable Fc-chimeric protein-based biomaterials are novel tool for advancing stem cell technology and regenerative medicine
- Author(s)
  Toshihiro Akaike
- Organizer
  第10回国際高分子カンファランス〔The10th　IPC2014)
- Place of Presentation
  つくば国際会議場
- Year and Date
  2014-12-02 – 2014-12-05
- Data Source
  KAKENHI-PROJECT-23220014
[Presentation] Design of Cell-recognizable Nano-biomaterials for ES/iPS Cell Proliferation and Differentiation －Cadherin-based "Cell-Cooking Plate"－
- Author(s)
  Akaike T.
- Organizer
  International Workshop on Stem Cell Differentiation:
- Place of Presentation
  Shanghai, China
- Invited
- Data Source
  KAKENHI-PROJECT-23220014
[Presentation] Promoting the Differentiation of Mouse Embryonic and Induced Pluripotent Stem Cells into Pancreatic ProgenitorCells on Recombinant E-cadherin Substratum.
- Author(s)
  Ali Motazedian, Amranul Haque,　Toshihiro　Akaike,
- Organizer
  9th World Biomaterials Congress,
- Place of Presentation
  Chengdu ,China
- Data Source
  KAKENHI-PROJECT-23220014
[Presentation] 培養皿固定型心筋分化誘導因子を用いたES/iPS細胞の効率的な心筋分化誘導
- Author(s)
  伊勢裕彦，湊彩や香，赤池敏宏
- Organizer
  日本バイオマテリアル学会シンポジウム2012
- Place of Presentation
  仙台国際センター（宮城県）
- Invited
- Data Source
  KAKENHI-PROJECT-23220014
[Presentation] New Trend of Cell-recognizable Polymers and Chimeric Proteins. －From Sugar-carrying Polymers to Cadherin and Cytokine Engineering for Regerative Medicine－
- Author(s)
  Akaike T.
- Organizer
  ATA 2nd Global Biomedical Materials Congress
- Place of Presentation
  Shanghai, China
- Invited
- Data Source
  KAKENHI-PROJECT-23220014
[Presentation] Cadherin-Matrix Engineering for new frontier of Cell Recognition Biomaterials
- Author(s)
  Toshihiro Akaike
- Organizer
  JSPS A3Foresight International Symposium on Nano-Biomaterials and Regenerative Medicine
- Place of Presentation
  Tokyo,Japan
- Year and Date
  2014-10-08 – 2014-10-09
- Invited
- Data Source
  KAKENHI-PROJECT-23220014
[Presentation] 肝臓モデルの3次元構築・培養を如何に達成するか？
- Author(s)
  赤池敏宏
- Organizer
  第12回日本再生医療学会総会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Invited
- Data Source
  KAKENHI-PROJECT-23220014
[Presentation] Self-renewal and Differentiation of ES and iPS Cells on Bioengineered Surfaces: Novel Approach of Cell-Cooking Plate.
- Author(s)
  Toshihiro Akaike, Amranul Haque, Xiao-ShanYue, Masato Nagaoka,
- Organizer
  9th World Biomaterials Congress
- Place of Presentation
  Chengdu, China
- Invited
- Data Source
  KAKENHI-PROJECT-23220014
[Presentation] A　chimera　protein　of　cell　adhesion　molecule　accelerates　neural　differentiation　of　mouse　induced　pluripotent stem cells.
- Author(s)
  K. Kutsuzawa, Motazedian A. T. Akaike,
- Organizer
  25th Annual and International Meeting of the Japanese Association for Animal Cell Technology (JAACT2012)
- Place of Presentation
  名古屋国際センター（愛知県）
- Data Source
  KAKENHI-PROJECT-23220014

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Akaike Toshihiro 赤池 敏宏

赤池 敏宏 アカイケ トシヒロ

AKAIKE Toshihiro 赤池 敏宏

赤池 敏弘 アカイケ トシヒロ

Research Projects

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Co-Researchers

Molecular level evaluation of cell culture substrate and construction of nano-controlled surface toward cell culture standardizationOngoing

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細胞認識性エクソソームを用いた臓器線維症に対する革新的治療法の開発Ongoing

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Design of Highly EMT-recognizable CarbonateApataite Nano-particles for Organ-Fibrosis and CancerPrincipal InvestigatorOngoing

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Regulation of functions and differentiation of ES/iPS cells by designing cell-recognizable chimera matricesPrincipal Investigator

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テーラーメイド治療への応用をめざすヒトiPS細胞の標準化培養器材の開発Principal Investigator

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Regulation of Stem Cells Gene Expression using Apatite nanocarriers coated with Cell-reconizable chimeric Protein.Principal Investigator

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遺伝子組換法による表面固定型キメラタンパク質の設計と再生医療用ES細胞の増殖制御Principal Investigator

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Akaike Toshihiro 赤池敏宏

赤池敏宏アカイケトシヒロ

AKAIKE Toshihiro 赤池敏宏

赤池敏弘アカイケトシヒロ