Hirayama Aki 平山暁

… Alternative Names

Researcher Number	20323298
Other IDs	https://orcid.org/0000-0001-5777-4208
Affiliation (Current)	2020: 筑波技術大学, 保健科学部, 教授
Affiliation (based on the past Project Information) *help	2009 – 2020: Tsukuba University of Technology, 保健科学部, 教授 2010: 筑波技術大学, 保健科学部, 特任教授 2007 – 2008: Tsukuba University of Technology, Faculty of Health Sceinces, Professor 2006: 筑波大学, 大学院人間総合科学研究科, 講師 2004: 筑波大学, 大学院・人間総合科学研究科, 講師 2001 – 2003: 筑波大学, 臨床医学系, 講師
Review Section/Research Field	Principal Investigator Kidney internal medicine / Kidney internal medicine / Rehabilitation science/Welfare engineering / Basic Section 52010:General internal medicine-related Except Principal Investigator Neurosurgery / General pharmacology / Kidney internal medicine / Applied health science / Medium-sized Section 9:Education and related fields / Basic Section 56010:Neurosurgery-related / Basic Section 52020:Neurology-related
Keywords	Principal Investigator 酸化ストレス / 電子スピン共鳴 / Nrf2 / ナノ粒子 / 慢性腎臓病 / ループス腎炎 / Carbamoyl-PROXYL / 一酸化窒素 / リポポリサッカライド / ESRイメージング … More Except Principal Investigator 脳梗塞 / フリーラジカル / 酸化ストレス / 糖尿病 / 循環器・高血圧 / シグナル伝達 / 薬理学 / Electron Spin Resonance / Cancer Stem Cell / Cell Cycle / Radiation / 脳腫瘍額 / 癌幹細胞 / 電子スピン共鳴 / がん幹細胞 / 細胞周期 / 遮光透析 / 紫外線除去フィルム / ダイアライザー / 血中過酸化脂質 / 1重項酸素 / 内皮型NOS / NO過剰産生 / ウサギの遮光透析モデル / 光遮断血液回路 / UVカット透析 / 一酸化窒素 / 過酸化脂質 / TBARS / PCOOH / 抗酸化能 / LIGHT SHIELDED HEMODIALYSIS / ULTRAVIOLET CUT FILM / DIALYZER / PLASMA LIPID PEROXIDES / SINGLET OXYGEN / ENDOTHELIAL NOS / NO OVERPRODUCTION / RABBIT MODEL OF LIGHT SHIELDED HEMODIALYSIS / 高齢者 / 慢性腎不全 / 血液透析 / 透析中の運動 / 運動様式 / 運動耐容能 / 筋力 / 生化学変化 / 維持透析 / 透析中の運動療法 / 透析中の電気刺激 / 安全性 / 有効性 / 身体運動機能 / 生化学検査 / 外来透析 / 負荷量可変型エルゴメータ / 電動式エルゴメータ / RCT / 慢性腎不全患者 / 血液透析患者 / 腎臓リハビリテーション / 電動アシスト自転車 / 負荷量可変型自転車 / 透析効率 / RNP / 脳虚血再灌流障害 / 血栓回収療法 / 神経血管ユニット保護 / 血液脳関門 / ナノ粒子化活性酸素消去剤 / 脳神経外科学 / 脳血管障害学 / 自閉症 / 社会性 / レドックスナノ粒子 / 口腔内間葉組織由来神経系細胞 / 細胞認識性カドヘリンマトリックス / 神経再生 / アルツハイマー病 / タウ / PETイメージング / 認知症 Less

レドックスナノ粒子と口腔内間葉組織由来神経系細胞による脳梗塞急性期再生医療の開発Ongoing
- Principal Investigator
  
  丸島愛樹
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  University of Tsukuba
Comprehensive PET imaging for oxidative stress and tau to clarify the pathogenesis of Alzheimer's diseaseOngoing
- Principal Investigator
  
  井川正道
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  University of Fukui
The bioenergetic dysfunction in ASD focusing on free radicalsOngoing
- Principal Investigator
  
  松崎秀夫
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 9:Education and related fields
- Research Institution
  University of Fukui
Analysis of antioxidative mechanism of "Hojin-zai", a traditional Kampo medicine, and it application to the new prooxidant therapy.Principal InvestigatorOngoing
- Principal Investigator
  
  平山暁
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Tsukuba University of Technology
ナノ粒子化活性酸素消去剤による脳虚血再灌流障害の神経血管ユニット保護療法の開発Ongoing
- Principal Investigator
  
  丸島愛樹
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  University of Tsukuba
Effects of a renal rehabilitation exercise program in elderly patients with chronic renal falure
- Principal Investigator
  
  Miura Misa
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied health science
- Research Institution
  Tsukuba University of Technology
Renal rehabilitation program oriented to oxidative stress controlPrincipal Investigator
- Principal Investigator
  
  Hirayama Aki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Rehabilitation science/Welfare engineering
- Research Institution
  Tsukuba University of Technology
Electron spin resonance live imaging for the metabolism and migration of radio-resistant brain tumor cells
- Principal Investigator
  
  MORITAKE Takashi
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurosurgery
- Research Institution
  University of Occupational and Environmental Health, Japan
Development of functional redox nanoparticle for long-term peritoneal dialysisPrincipal Investigator
- Principal Investigator
  
  AKI HIRAYAMA
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Tsukuba University of Technology
Development of an antioxidative nano-particle for redox sensoring and reno-protectionPrincipal Investigator
- Principal Investigator
  
  HIRAYAMA Aki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Tsukuba University of Technology
Study on roles of a novel NADPH oxidase isoform in the development of lifestyle related diseases
- Principal Investigator
  
  YABE Chihiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kyoto Prefectural University of Medicine
Non-invasive Redox Imaging for the Pathophysiological Analysis of Hypertensive Renal Disease and Development of Antioxidative TherapyPrincipal Investigator
- Principal Investigator
  
  HIRAYAMA Aki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Tsukuba University of Technology
  University of Tsukuba
腎疾患における生体内酸化ストレス動態の非侵襲的画像化解析と抗酸化療法への応用Principal Investigator
- Principal Investigator
  
  平山暁
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  University of Tsukuba
Development of New Method of Hemodialysis Using Light Shielded Dialyzer and Blood Circuit
- Principal Investigator
  
  NAGASE Sohji
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  University of Tsukuba
in vivo 3次元ESRによる腎疾患モデル動物の生体内酸化・抗酸化動態解析Principal Investigator
- Principal Investigator
  
  平山暁
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  University of Tsukuba

[Book] Application of EPR Imaging to the Pathophysiological Analysis of Acute Renal Failure and Antioxidative Effects of Erythropoietin. In The Proceedings of the 12th Biennial Meeting of the Society for Free Radical Research International.2005
- Author(s)
  Hirayama A.et al.(edited by Boveris A.et al.)
- Total Pages
  395
- Publisher
  Medimond S.r.l.(Bologna, Italy)
- Data Source
  KAKENHI-PROJECT-15790427
[Book] 腎とフリーラジカル第7集・ESRイメージングによる腎抗酸化能変化のin vivo無侵襲定量解析法の確立とエリスロポエチンによる臓器保護効果測定への応用2004
- Author(s)
  平山暁他
- Total Pages
  190
- Publisher
  東京医学社・東京
- Data Source
  KAKENHI-PROJECT-15790427
[Journal Article] The visualization methods of occluded dural sinus for safe transvenous embolization of dural AVFs2019
- Author(s)
  Hosoo H, Tsuruta W, Nakai Y, Shiigai M, Sato M, Ito Y, Takigawa T, Marushima A, Ishikawa E, Yamamoto T, Matsumaru Y, Matsumura A.
- Journal Title
  
  World Neurosurgery
  
  Volume: 印刷中
- DOI
  10.1016/j.wneu.2019.02.250
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10819
[Journal Article] 症例鼻出血で発症した海綿静脈洞部内頚動脈解離性動脈瘤の1例2018
- Author(s)
  Kino H, Tsuruta W, Ito Y, Takigawa T, Shiigai M, Marushima A, Nakai Y, Yamamoto T, Matsumura A
- Journal Title
  
  Neurological Surgery 脳神経外科
  
  Volume: 46 Issue: 9 Pages: 789-795
- DOI
  10.11477/mf.1436203815
- ISSN
  0301-2603, 1882-1251
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10819
[Journal Article] Improving the neurological prognosis following OHCA using real-time evaluation of cerebral tissue oxygenation2018
- Author(s)
  Koyama Y, Inoue Y, Hisago S, Marushima A, Hagiya K, Yamasaki Y, Enomoto Y, Shimojo N, Kawano S, Mizutani T
- Journal Title
  
  American Journal of Emergency Medicine
  
  Volume: 36
- DOI
  10.1016/j.ajem.2017.11.029
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10819, KAKENHI-PROJECT-17K19787, KAKENHI-PROJECT-17K17623
[Journal Article] Clinical significance of redox effects of Kampo formulae, a traditional Japanese herbal medicine: comprehensive estimation of multiple antioxidative activities2018
- Author(s)
  Hirayama Aki、Oowada Shigeru、Ito Hiromu、Matsui Hirofumi、Ueda Atsushi、Aoyagi Kazumasa
- Journal Title
  
  J. Clin. Biochem. Nutr.
  
  Volume: 62 Issue: 1 Pages: 39-48
- DOI
  10.3164/jcbn.17-59
- NAID
  130006301228
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K12575
[Journal Article] Preliminary in vivo magnetofection data using magnetic calcium phosphate nanoparticles immobilizing DNA and iron oxide nanocrystals2018
- Author(s)
  Shubhra Quazi T.H.、Oyane Ayako、Nakamura Maki、Puentes Sandra、Marushima Aiki、Tsurushima Hideo
- Journal Title
  
  Data in Brief
  
  Volume: 18 Pages: 1696-1701
- DOI
  10.1016/j.dib.2018.04.058
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10819, KAKENHI-PROJECT-16H03831
[Journal Article] Spinal Cord Infarction in the Region of the Posterior Spinal Artery After Embolization for Vertebral Artery Dissection2018
- Author(s)
  Tsuruta Wataro、Yamamoto Tetsuya、Ikeda Go、Sato Masayuki、Ito Yoshiro、Takigawa Tomoji、Marushima Aiki、Nakai Yasunobu、Matsumaru Yuji、Matsumura Akira
- Journal Title
  
  Operative Neurosurgery
  
  Volume: 15 Pages: 701-710
- DOI
  10.1093/ons/opy026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10819
[Journal Article] Treatment Strategy Based on Plaque Vulnerability and the Treatment Risk Evaluation for Internal Carotid Artery Stenosis2018
- Author(s)
  ITO Yoshiro、TSURUTA Wataro、NAKAI Yasunobu、TAKIGAWA Tomoji、MARUSHIMA Aiki、MASUMOTO Tomohiko、MATSUMARU Yuji、ISHIKAWA Eiichi、MATSUMURA Akira
- Journal Title
  
  Neurologia medico-chirurgica
  
  Volume: 58 Issue: 5 Pages: 191-198
- DOI
  10.2176/nmc.oa.2017-0228
- NAID
  130006734354
- ISSN
  0470-8105, 1349-8029
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10819
[Journal Article] Intensive Gait Treatment Using a Robot Suit Hybrid Assistive Limb in Acute Spinal Cord Infarction: Report of Two Cases2017
- Author(s)
  Watanabe H, Marushima A, Kawamoto H, Kadone H, Ueno T, Shimizu Y, Endo A, Hada Y, Saotome K, Abe T, Yamazaki M, Sankai Y, Ishikawa E, Matsumura A
- Journal Title
  
  J Spinal Cord Med
  
  Volume: 9 Pages: 1-7
- DOI
  10.1080/10790268.2017.1372059
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10819
[Journal Article] Combination Therapy with Peritoneal Dialysis and Hemodialysis from the Initiation of Renal Replacement Therapy Preserves Residual Renal Function and Serum Albumin.2017
- Author(s)
  A Ueda, K Nagai, A Hirayama, C Saito, K Yamagata
- Journal Title
  
  Advances in peritoneal dialysis
  
  Volume: 33 Pages: 74-78
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K12575
[Journal Article] Nurovascular unit protection from cerebral ischemia-reperfusion injury by radical-containing nanoparticles in mice2017
- Author(s)
  Hosoo H, Marushima A, Nagasaki Y, Hirayama A, Ito H, Puentes S, Mujagic A, Tsurushima H, Tsuruta W, Suzuki K, Matsui H, Matsumaru Y, Yamamoto T, Matsumura
- Journal Title
  
  Stroke
  
  Volume: 48 Pages: 2238-2247
- DOI
  10.1161/strokeaha.116.016356
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10819, KAKENHI-PROJECT-25220203, KAKENHI-PROJECT-16K15628
[Journal Article] Training with an Electric Exercise Bike versus a Conventional Exercise Bike during Hemodialysis for Patients with End-stage Renal Disease: A Randomized Clinical Trial2017
- Author(s)
  Miura M, Yoshizawa R, Oowada S, Hirayama A, Ito O, Kohzuki M, Maeba T.
- Journal Title
  
  PRM
  
  Volume: 2 Issue: 0 Pages: 20170008-20170008
- DOI
  10.2490/prm.20170008
- NAID
  130007042064
- ISSN
  2432-1354
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H02118, KAKENHI-PROJECT-15K01702, KAKENHI-PROJECT-15K12575
[Journal Article] Exercise Program for Chronic Kidney Disease Improves Pathophysiological Condition with a Shift of Oxidative Stress2017
- Author(s)
  Hirayama Aki、Miura Misa、Yasuda Go、Nagano Yumiko、Matsui Hirofumi、Hirayama Yoh、Ueda Atsushi、Aoyagi Kazumasa、Kohzuki Masahiro、Oowada Shigeru
- Journal Title
  
  Free Radical Biology and Medicine
  
  Volume: 112 Pages: 131-132
- DOI
  10.1016/j.freeradbiomed.2017.10.200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K12575
[Journal Article] 視覚障害学生に対する喀痰吸引モデル使用の経験2017
- Author(s)
  三浦美佐，上月正博，松下昌之助，平山暁，石塚和重
- Journal Title
  
  ロービジョン学会誌
  
  Volume: 1 Pages: 1-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K01702
[Journal Article] 2015　国際学会報告2016
- Author(s)
  三浦美佐，平山暁，大和田滋，前波輝彦，小川佳子，伊藤修，上月正博
- Journal Title
  
  筑波技術大学テクノレポート
  
  Volume: 23(2) Pages: 50-53
- Data Source
  KAKENHI-PROJECT-15K01702
[Journal Article] 理学療法士による運動とその効果．CKD患者のサルコペニア・フレイル2016
- Author(s)
  三浦美佐,平山暁
- Journal Title
  
  腎と透析
  
  Volume: 80.5 Pages: 745-750
- Data Source
  KAKENHI-PROJECT-15K01702
[Journal Article] Effects of a renal rehabilitation exercise program in patients with CKD: Controlled trial.2015
- Author(s)
  Miura M, Hirayama A, Oowada S, Ito O, Kohzuki M.
- Journal Title
  
  F1000 Research
  
  Volume: 1 Pages: 421-421
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K01702
[Journal Article] Design and use of silica-containing redox nanoparticles, siRNPs, for high-performance peritoneal dialysis2014
- Author(s)
  Yukio Nagasaki, Tatsuya Yaguchi, Takuma Matsumura, Toru Yoshitomi, Yutaka Ikeda, Atsushi Ueda, and Aki Hirayama
- Journal Title
  
  Biomaterials Science
  
  Volume: 2 Pages: 522-528
- DOI
  10.1039/c3bm60236b
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-13J06119, KAKENHI-PROJECT-24591224, KAKENHI-PUBLICLY-25107707, KAKENHI-PROJECT-25220203
[Journal Article] Reactive Oxygen Species-Scavenging Nanomedicines for the Treatment of Oxidative Stress Injuries2014
- Author(s)
  Toru Yoshitomi, Yukio Nagasaki
- Journal Title
  
  Advanced Healthcare Materials
  
  Volume: 3 Pages: 1149-1161
- DOI
  10.1002/adhm.201300576
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-13J06119, KAKENHI-PROJECT-24591224, KAKENHI-PROJECT-25220203
[Journal Article] Redox-active Injectable Gel Using Thermo-responsive Nanoscale Polyion Complex Flower Micelle for Noninvasive Treatment of Local Inflammation,2013
- Author(s)
  Pua ML, Yoshitomi T, Chonpathompikunlert P, Hirayama A, Nagasaki Y
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 172 Pages: 914-920
- DOI
  10.1016/j.jconrel.2013.10.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591224, KAKENHI-PROJECT-24659920, KAKENHI-PUBLICLY-25107707, KAKENHI-PROJECT-25220203
[Journal Article] The ROS scavenging and renalprotective effects of pH-responsive nitroxide radical containingnanoparticles.2011
- Author(s)
  Toru Yoshitomi, Aki Hirayama, Yukio Nagasaki
- Journal Title
  
  Biomaterials
  
  Volume: 32 Pages: 8021-8
- DOI
  10.1016/j.biomaterials.2011.07.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21240050, KAKENHI-PROJECT-21591018, KAKENHI-PROJECT-22659008
[Journal Article] Newly Synthesized Radical-containing Nanoparticles (RNP) Enhance Neuroprotection after Cerebral Ischemia-reperfusion Injury2011
- Author(s)
  Aiki Marushima, Hideo Tsurusima, Toru Yoshitomi, Kazuko Toh, Aki Hirayama, Yukio Nagasaki, Akira Matumura
- Journal Title
  
  Neurosurgery
  
  Volume: 68 Pages: 1418-1426
- DOI
  10.1227/neu.0b013e31820c02d9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21240050, KAKENHI-PROJECT-21591018, KAKENHI-PROJECT-22800004
[Journal Article] Development of a pH-Sensitive Reno-Protective Nano-Particle for Relief of Ischemia-Reperfusion Acute Kidney Injury.2010
- Author(s)
  Hirayama A
- Journal Title
  
  Journal of American Society of Nephrology
  
  Volume: 21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591018
[Journal Article] Spherical carbon adsorbent (AST-120) protects deterioration of renal function in chronic kidney disease rats through inhibition of reactive oxygen species production from mitochondria and reduction of serum lipid peroxidation2010
- Author(s)
  Owada S, Maeba T, Sugano Y, Hirayama A, Ueda A, Nagase S, Goto S, Nishijima F, Bannai K, Yamato H
- Journal Title
  
  Nephron Exp Nephrol
  
  Volume: 115(4)
- Data Source
  KAKENHI-PROJECT-21591018
[Journal Article] pH-Sensitive Radical.Containing-Nanoparticle (RNP) for theL-Band-EPR Imaging of Low pH Circumstances2009
- Author(s)
  Yoshitomi T, Suzuki R, Mamiya T, Matsui H, Hirayama A, Nagasaki Y.
- Journal Title
  
  Bioconjugate Chem
  
  Volume: 20 Pages: 1792-1798
- Data Source
  KAKENHI-PROJECT-21591018
[Journal Article] NADPH oxidase isoforms and anti-hypertensive effects of atorvastatin demonstrated in two animal models.2009
- Author(s)
  Cui W, Matsuno K, Iwata K, Ibi M, Katsuyama M, Kakehi T, Sasaki M, Ikami K, Zhu K, Yabe-Nishimura C.
- Journal Title
  
  J Pharmacol Sci 111
  
  Pages: 260-268
- NAID
  10026154161
- Data Source
  KAKENHI-PROJECT-20390071
[Journal Article] In vivo imaging of renal redox status during azelnidpine treatments2008
- Author(s)
  Hirayama A.
- Journal Title
  
  Hypertension Research (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590878
[Journal Article] In vivo imaging of renal redox status during azelnidpine treatments2008
- Author(s)
  Hirayama A.
- Journal Title
  
  Hypertension Research (印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590878
[Journal Article] The AP-1 site is essential for the promoter activity of NOX1/NADPH oxidase, a vascular superoxide-producing enzyme : Possible involvement of the ERK1/2-JunB pathway.2008
- Author(s)
  Cevik MO, Katsuyama M, Kanda S, Kaneko T, Iwata K, Ibi M, Matsuno K, Kakehi T, Cui W, Sasaki M, Yabe-Nishimura C.
- Journal Title
  
  Biochem Biophys Res Commun 374
  
  Pages: 351-355
- Data Source
  KAKENHI-PROJECT-20390071
[Journal Article] Renal redox imaging and in vivo analysis during antihypertensive treatments.2006
- Author(s)
  Hirayama A
- Journal Title
  
  Nephrology Dialysis Transplantation 21・Suppl.4
  
  Pages: 41-42
- Data Source
  KAKENHI-PROJECT-18590878
[Journal Article] Electron paramagnetic resonance imaging of oxidative stress in renal disease.2006
- Author(s)
  Hirayama A
- Journal Title
  
  Nephron Clinical Practice 103
- Data Source
  KAKENHI-PROJECT-18590878
[Journal Article] In vivo imaging of oxidative stress in ischemia-reperfusion renal injury using electron paramagnetic resonance.2005
- Author(s)
  Hirayama A. et al.
- Journal Title
  
  American Journal of Physiology Renal Physiology 208・3
- Data Source
  KAKENHI-PROJECT-15790427
[Journal Article] EPR imaging of reducing activity in Nrf2 transcriptional factor deficient mice.2003
- Author(s)
  Hirayama A. et al.
- Journal Title
  
  Free Radical Biology & Medicine 34・10
  
  Pages: 1236-1242
- Data Source
  KAKENHI-PROJECT-15790427
[Journal Article] Oxidative stress during leukocyte absorption apheresis2003
- Author(s)
  Hirayama A. et al.
- Journal Title
  
  Journal of Clinical Apheresis 18・2
  
  Pages: 61-66
- Data Source
  KAKENHI-PROJECT-15790427
[Journal Article] Electron paramagnetic resonance imaging of nitric oxide organ distribution in lipopolysuccaride treated mice2003
- Author(s)
  Hirayama A. et al.
- Journal Title
  
  Molecular and Cellular Biochemistry 244・1
  
  Pages: 63-67
- Data Source
  KAKENHI-PROJECT-15790427
[Patent] 高分子環状ニトロキシドラジカル化合物とシリカの有機―無機ハイブリッド複合体2013
- Inventor(s)
  長崎幸夫，吉冨　徹，平山　暁他
- Industrial Property Rights Holder
  長崎幸夫，池田　豊，吉冨　徹，植田敦志，平山　暁，他
- Industrial Property Rights Type
  特許
- Filing Date
  2013-02-06
- Overseas
- Data Source
  KAKENHI-PROJECT-24591224
[Patent] 高分子環状ニトロキシドラジカル化合物とシリカの有機.無機ハイブリッド複合体2012
- Inventor(s)
  長崎幸夫,吉冨徹,池田豊,植田敦志,平山暁,矢口達也,山下真代
- Industrial Property Rights Holder
  国立大学法人筑波大学,国立大学法人筑波技術大学
- Industrial Property Number
  2012-024460
- Filing Date
  2012-02-07
- Data Source
  KAKENHI-PROJECT-21591018
[Patent] 高分子環状ニトロキシドラジカル化合物とシリカの有機-無機ハイブリッド複合体2012
- Inventor(s)
  長崎幸夫, 吉冨徹, 池田豊, 植田敦志, 平山暁, 矢口達也, 山下真代
- Industrial Property Rights Holder
  長崎幸夫, 吉冨徹, 池田豊, 植田敦志, 平山暁, 矢口達也, 山下真代および国立大学法人筑波大学国立大学法人筑波技術大学
- Industrial Property Number
  2012-024460
- Filing Date
  2012-02-07
- Data Source
  KAKENHI-PROJECT-21591018
[Patent] Polymerized cyclic nitro-xide radical compound, and use thereof2010
- Inventor(s)
  NAGASAKI, Yukio. YOSHITOMI, Toru. MATSUI, Hirofumi. HIRAYAMA, Aki. MAMIYA, Takashi. MATSUMUR A, Akira. SUZUKI, Kensuke. TSURUSHIM A, Hideo. MARUSHIMA, Aiki. TOH, Kazuko MIYAMOTO, Daisuke
- Industrial Property Rights Holder
  NAGASAKI, Yukio. YOSHITOMI, Toru. MATSUI, Hirofumi. HIRAYAMA, Aki. MAMIYA, Takashi. MATSUMUR A, Akira. SUZUKI, Kensuke. TSURUSHIM A, Hideo. MARUSHIMA, Aiki. TOH, Kazuko MIYAMOTO, DaisukeおよびUniversity of Tsukuba
- Filing Date
  2010-11-02
- Overseas
- Data Source
  KAKENHI-PROJECT-21591018
[Patent] Polymerized cyclic nitro-xide radical compound, and use thereof2010
- Inventor(s)
  NAGASAKI, Yukio. YOSHITOMI, Toru. MATSUI, Hirofumi. HIRAYAMA, Aki. MAMIYA, Takashi. MATSUMUR A, Akira. SUZUKI, Kensuke. TSURUSHIM A, Hideo. MARUSHIMA, Aiki. TOH, Kazuko MIYAMOTO, Daisuke
- Industrial Property Rights Holder
  NAGASAKI, Yukio. YOSHITOMI, Toru. MATSUI, Hirofumi. HIRAYAMA, Aki. MAMIYA, Takashi. MATSUMUR A, Akira. SUZUKI, Kensuke. TSURUSHIM A, Hideo. MARUSHIMA, Aiki. TOH, Kazuko MIYAMOTO, DaisukeおよびUniversity of Tsukuba
- Filing Date
  2010-11-02
- Data Source
  KAKENHI-PROJECT-21591018
[Patent] Polymerized cyclic nitroxide radical compound, and use thereof2009
- Inventor(s)
  NAGASAKI, Yukio. YOSHITOMI, Toru. MATSUI, Hirofumi. HIRAYAMA, Aki. MAMIYA, Takashi. MATSU-MURA, ra. SUZUKI, Kensuke. TSURUSHI-MA, Hideo. MARUSHI-MA, AiKi. TOH, Kazuko. MIYAMOTO, Daisuke
- Industrial Property Rights Holder
  NAGASAKI, Yukio. YOSHITOMI, Toru. MATSUI, Hirofumi. HIRAYAMA, Aki. MAMIYA, Takashi. MATSU-MURA, ra. SUZUKI, Kensuke. TSURUSHI-MA, Hideo. MARUSHI-MA, AiKi. TOH, Kazuko. MIYAMOTO, Daisukeおよび University of Tsukuba
- Filing Date
  2009-05-11
- Overseas
- Data Source
  KAKENHI-PROJECT-21591018
[Patent] Polymerized cyclic nitroxide radical compound, and use thereof2009
- Inventor(s)
  NAGASAKI Yukio, YOSHITOMI Toru, MATSUI Hirofumi, HIRAYAMA Aki,MAMIYA Takashi, MATSUMURA Akira, SUZUKI Kensuke, TSURUSHIMA Hideo,MARUSHIMA Aiki, TOH Kazuko, MIYAMOTO Daisuke
- Industrial Property Rights Holder
  NAGASAKI Yukio, YOSHITOMI Toru, MATSUI Hirofumi, HIRAYAMA Aki, MAMIYA Takashi, MATSUMURA Akira, SUZUKI Kensuke, TSURUSHIMA Hideo, MARUSHIMA Aiki, TOH Kazuko, MIYAMOTO Daisuke, University of Tsukuba
- Filing Date
  2009-05-11
- Overseas
- Data Source
  KAKENHI-PROJECT-21591018
[Patent] Polymerized cyclic nitroxide radical compound, and use thereof2009
- Inventor(s)
  NAGASAKI, Yukio. YOSHITOMI, Toru. MATSUI, Hirofumi. HIRAYAMA, Aki. MAMIYA, Takashi. MATSUMURA, Akira. SUZUKI, Kensuke. TSURUSHIMA, Hideo. MARUSHIMA, Aiki. TOH, Kazuko. MIYAMOTO, Daisuke
- Industrial Property Rights Holder
  同左およびUniversity of Tsukuba
- Filing Date
  2009-05-11
- Overseas
- Data Source
  KAKENHI-PROJECT-21591018
[Presentation] 脳梗塞急性期再開通療法における環境応答性ナノ粒子化活性酸素消去剤（RNP）による脳保護療法の開発2018
- Author(s)
  丸島愛樹、細尾久幸、長崎幸夫、Mujagic A、Puentes S、平山暁、鈴木謙介、滝川知司、早川幹人、伊藤嘉朗、鶴嶋英夫、松井裕史、石川栄一、井上貴昭、松丸祐司、松村明
- Organizer
  第43回日本脳卒中学会学術集会
- Data Source
  KAKENHI-PROJECT-17K10819
[Presentation] 脳梗塞急性期血栓回収療法におけるナノ粒子化活性酸素消去剤(RNP)による脳保護療法の開発2018
- Author(s)
  丸島愛樹、長崎幸夫、Mujagic A、高橋利英、渡部大輔、松村英明、Ting M、Puentes S、細尾久幸、平山暁、鈴木謙介、滝川知司、石川栄一、井上貴昭、松丸祐司、松村明
- Organizer
  第61回日本脳循環代謝学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17K10819
[Presentation] Long Term Renal Rehabilitation Induces a Significant Shift in Serum Antioxidative Profile.2018
- Author(s)
  Hirayama A, Ueda A, Miura M, Yasuda G, Nishida A, Hirayama Y, Kohzuki M, Oowada S.
- Organizer
  Annual Dialysis Conference 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12575
[Presentation] 抗酸化ナノメディシン(RNP)による急性脳主幹動脈閉塞に対する脳保護療法の開発2018
- Author(s)
  丸島愛樹、長崎幸夫、細尾久幸、Mujagic A、松村英明、渡部大輔、Puentes S、平山暁、松井裕史、鈴木謙介、滝川知司、早川幹人、佐藤允之、伊藤嘉朗、石川栄一、井上貴昭、松丸祐司、松村明
- Organizer
  第33回日本酸化ストレス学会関東支部会
- Data Source
  KAKENHI-PROJECT-17K10819
[Presentation] 毛細血管・赤血球の異常を再現したお血類似病態のライブイメージングと，駆お血剤による血流動態及び NO 産生効果の動画解析2018
- Author(s)
  平山暁，富田勉，青柳一正．
- Organizer
  第69回日本東洋医学会学術総会
- Data Source
  KAKENHI-PROJECT-18K07437
[Presentation] ライブイメージング技術の応用による駆お血剤薬理効果定量解析の試み2018
- Author(s)
  平山暁，富田勉，青柳一正．
- Organizer
  第75回日本東洋医学会関東甲信越支部学術総会
- Data Source
  KAKENHI-PROJECT-18K07437
[Presentation] ミニシンポジウム　「臨床現場でのESR応用」2018
- Author(s)
  平山　暁
- Organizer
  第57回電子スピンサイエンス学会(SEST2018)
- Invited
- Data Source
  KAKENHI-PROJECT-18K07437
[Presentation] ナノ粒子化活性酸素消去剤（RNP）による神経保護療法の実用化を目指した研究開発2018
- Author(s)
  丸島愛樹、長崎幸夫、Mujagic A、高橋利英、渡部大輔、松村英明、Ting M、Puentes S、細尾久幸、平山暁、鈴木謙介、滝川知司、石川栄一、井上貴昭、松丸祐司、松村明
- Organizer
  日本脳神経外科学会第77回学術総会
- Data Source
  KAKENHI-PROJECT-17K10819
[Presentation] Neurovascular Unit Protection Using Nitroxide Radicals-containing Nanoparticles (TEMPO-RNP) for Cerebral Ischemia-reperfusion Injury in Mice2018
- Author(s)
  Hisayuki Hosoo, Aiki Marushima, Yukio Nagasaki, Aki Hirayama, Hiromu Ito, Sandra Puentes, Arnela Mujagic, Hideo Tsurushima, Wataro, Kensuke Suzuki; Hirofumi Matsui, Yuji Matsumaru, Tetsuya Yamamoto, Akira Matsumura
- Organizer
  International stroke conference 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10819
[Presentation] 活性酸素消去剤封入ナノ粒子(RNP)による脳虚血再灌流障害に対するNeurovascular unit保護効果2017
- Author(s)
  丸島愛樹、細尾久幸、長崎幸夫、平山暁、Sandra Puentes、Arnela Mujagic 、伊藤紘、鶴嶋英夫、鶴田和太郎、鈴木謙介、松井裕史、松丸祐司、山本哲哉、松村明
- Organizer
  第60回脳循環代謝学会
- Data Source
  KAKENHI-PROJECT-17K10819
[Presentation] Exercise program for chronic kidney disease improves pathophysiological condition with a shift of oxidative stress.2017
- Author(s)
  Hirayama A, Miura M, Yasuda G, Nagano Y, Matsui H, Hirayama Y, Ueda A, Aoyagi K, Kohzuki M, Oowada S.
- Organizer
  The Society for Redox Biology and Medicine's 24th Annual Meeting (SfRBM 2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12575
[Presentation] OXIDATIVE STRESS DURING RENAL REHABILITATION2017
- Author(s)
  Hirayama A, Miura M, Hirayama Y, Nagano Y, Yasuda G, Ueda A, Matsui H, Aoyagi K, Kozuki M, Oowada S.
- Organizer
  World Conference of Nephrology 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12575
[Presentation] Redox nano-particle for peritoneal dialysis solution2017
- Author(s)
  Hirayama A, Nagasaki Y, Yaguchi T, Matsumura T, Yoshitomi T, Ikeda Y, Ueda A.
- Organizer
  Annual Dialysis Conference 2017
- Place of Presentation
  Long Beach Convention Center, Long Beach, CA, USA
- Year and Date
  2017-03-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12575
[Presentation] 性腎臓病進行抑制のため自宅での電気刺激療法を試みた1症例2017
- Author(s)
  三浦美佐，斎藤知栄，平山暁，伊藤修，上月正博，山縣邦弘
- Organizer
  日本腎臓リハビリテーション学会
- Data Source
  KAKENHI-PROJECT-15K01702
[Presentation] Advantages of nutrition counseling in CKD patients by a professional dietician on the physical or psychological state．2016
- Author(s)
  Ueda A, Hirayama A, Yamagata K.
- Organizer
  ASN Kidney Week 2016 Annual Meeting of the American Society of Nephrlogy
- Place of Presentation
  McCormic Place, Chicago, IL., USA
- Year and Date
  2016-11-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12575
[Presentation] Effects of a renal rehabilitation exercise program in patients with end stage renal disease: study protocol for a multi-center controlled trial.2016
- Author(s)
  Miura M, Oowada S, Hirayama Y, Hirayama A, Ito O, Kohzuki M.
- Organizer
  10th Interantional Soceity of Physical and Rehabilitation Medicine World Congress.
- Place of Presentation
  Kuala Lumpur Convention Centre
- Year and Date
  2016-05-29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12575
[Presentation] 透析中の運動療法での高齢透析患者の酸化ストレス消去活性への影響2016
- Author(s)
  三浦美佐,平山暁, 大和田滋,平山陽,伊藤修,上月正博
- Organizer
  第 28 回腎とフリーラジカル研究会
- Place of Presentation
  つくば国際会議場, 茨城県
- Data Source
  KAKENHI-PROJECT-15K01702
[Presentation] Effects of a renal rehabilitation exercise program in patients with end-stage renal disease: study protocol for a multicenter controlled trial2016
- Author(s)
  M. Miura, M. Kohzuki, S. Oowada, Y. Hirayama, O. Ito,A. Hirayama.
- Organizer
  10th World Congress of the International Society of Physical and Rehabilitation Medicine
- Place of Presentation
  Kuala Lumpur, Malaysia
- Year and Date
  2016-05-29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01702
[Presentation] Comparison of electric bike exercise to conventional bicycle training during hemodialysis sessions on physical function in patients with end stage renal disease2016
- Author(s)
  M Miura , R Yoshizawa, S Oowada, A Hirayama, O Ito, Y Hirayama, M Kohzuki, T Maeba
- Organizer
  American Society of Nephrology（Kidney Week 2016）
- Place of Presentation
  Chicago, America
- Year and Date
  2016-11-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01702
[Presentation] 血液透析中の運動療法または下肢電気刺激は身体機能を改善する：多施設共同治験2016
- Author(s)
  [3]平山真喜子,吉澤亮,戀塚ゆかり,鈴木志穂,鈴木綾子, 三浦美佐,大和田滋,前波輝彦
- Organizer
  第 6 回日本腎臓リハビリテーション学会
- Place of Presentation
  大阪国際会議場, 大阪府
- Year and Date
  2016-06-09
- Data Source
  KAKENHI-PROJECT-15K01702
[Presentation] Effects of Aerobic Training and Electrical Stimulation to Skeletal Muscles during Hemodialysis for Patients with End-Stage Renal Disease.2015
- Author(s)
  Miura M, Hirayama A, Oowada S, Ito O, Kohzuki M.
- Organizer
  9th World Congress of the International Society of Physical and Rehabilitation Medicine
- Place of Presentation
  Berlin, Germany
- Year and Date
  2015-06-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01702
[Presentation] 血液透析中の運動療法や下肢電気刺激は身体機能を改善する2015
- Author(s)
  三浦美佐，平山　暁，大和田滋，伊藤　修，上月正博
- Organizer
  第60回日本透析医学会学術集会
- Place of Presentation
  みなとみらい，横浜市
- Year and Date
  2015-06-26
- Data Source
  KAKENHI-PROJECT-15K12575
[Presentation] 血液透析患者の酸化ストレスは抗酸化力の減弱ではなく変質による2015
- Author(s)
  平山暁，植田敦志，大和田滋，永瀬宗重，青柳一正
- Organizer
  第60回日本透析医学会学術集会
- Place of Presentation
  みなとみらい，横浜市
- Year and Date
  2015-06-26
- Data Source
  KAKENHI-PROJECT-15K12575
[Presentation] Multicenter trial of aerobic exercise in maintenance hemodialysis patients: Clinical and biochemical effects.2015
- Author(s)
  Miura M, Hirayama A, Oowada S, Hirayama Y, Ito O, Kohzuki M.
- Organizer
  2015 ASN
- Place of Presentation
  San Diego, America
- Year and Date
  2015-11-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01702
[Presentation] Multicenter trial of aerobic exercise in maintenance hemodialysis patients : Clinical and biochemical effects.2015
- Author(s)
  Miura M, Hirayama A, Oowada S, Ito O, Hirayama Y, Kohzuki M.
- Organizer
  2015 Annual Meeting of the American Society of Nephrology
- Place of Presentation
  San Diego, CA, USA
- Year and Date
  2015-11-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12575
[Presentation] Oxidative Stress of Chronic Kidney Disease (CKD) Patients Changes in Quality, Not in Quantity.2015
- Author(s)
  Hirayama A, Oowada S, Ueda A, Aoyagi K.
- Organizer
  7th Biennial Meeting of Society for Free Radical Research-Asia.
- Place of Presentation
  Chiang-Mai, Thailand
- Year and Date
  2015-11-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12575
[Presentation] Effects of a renal rehabilitation exercise program in patients with CKD: Controlled trial.2015
- Author(s)
  Miura M, Hirayama A, Oowada S, Ito O, Kohzuki M.
- Organizer
  52th ERA-EDTA
- Place of Presentation
  London, England
- Year and Date
  2015-05-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01702
[Presentation] Design of Nanoparticle therapeutics for ischemia reperfusion injuries.2014
- Author(s)
  Nagasaki Y, Yoshitomi T, Toh K, Marushima A, Tsurushima H, Suzuki K, Matsumura A, Hirayama A, Sanada S, Yoshida A, Kitakaze M.
- Organizer
  2nd International Meeting on Ischemia Reperfusion Injury in Transplantation.
- Place of Presentation
  Poitiers (France)
- Year and Date
  2014-04-25
- Data Source
  KAKENHI-PROJECT-24591224
[Presentation] Preparation and evaluation of silica-containing redox nanoparticle for peritoneal dialysis which aimed at the medical treatment of chronic renal failure2013
- Author(s)
  Matsumura T, Yaguchi T, Amraon Md, Ikeda Y, Yoshitomi T, Hirayama A, Ueda A, Nagasaki Y
- Organizer
  Tsukuba International Conference on Materials Science
- Place of Presentation
  Tsukuba International Congress Center, Tsukuba
- Data Source
  KAKENHI-PROJECT-24591224
[Presentation] Uremic toxin indoxyl sulfate induce mitochondrial superoxide leakage.2012
- Author(s)
  Hirayama A
- Organizer
  19th Annual Meeting of the Society for Free Radical Biology and Medicine
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-24591224
[Presentation] Application of ESR and Spin Technologies for the Control of Kidney Diseases2011
- Author(s)
  Hirayama A, Ueda A, Nagase S, Aoyagi K, Owada S
- Organizer
  International Workshop"Advanced ESR Studies for New Frontiers in Biofunctional Spin Science and Technology"(AEBST 2011)
- Place of Presentation
  Kobe
- Year and Date
  2011-11-13
- Data Source
  KAKENHI-PROJECT-21591018
[Presentation] 急性腎障害に対するナノ粒子治療の開発シンポジウムJapan Kidney Week 20112011
- Author(s)
  平山暁,吉富徹,長崎幸夫
- Organizer
  第55回(社)日本透析医学会学術集会・総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21591018
[Presentation] Indoxyl sulfate and guanidino succinic acid directly induce mitochondrial superoxide production2011
- Author(s)
  Hirayama A.
- Organizer
  XLVIII ERA-EDTA Congress
- Place of Presentation
  Prague
- Data Source
  KAKENHI-PROJECT-21591018
[Presentation] レドックス反応性ナノ粒子による腎虚血再灌流障害の治療第2011
- Author(s)
  吉冨徹,平山暁,長崎幸夫
- Organizer
  64回日本酸化ストレス学会学術集会
- Place of Presentation
  北海道,ルスツ
- Data Source
  KAKENHI-PROJECT-21591018
[Presentation] Novel redox nanotherapy fof renal ischemia reperfusion injury2011
- Author(s)
  Nagasaki Y.
- Organizer
  XLVIII ERA-EDTA Congress
- Place of Presentation
  Prague
- Data Source
  KAKENHI-PROJECT-21591018
[Presentation] Novel redox nanotherapy fof renal ischemia reperfusion injury2011
- Author(s)
  Nagasaki Y, Yoshitomi T, Hirayama A
- Organizer
  XLVIII ERA-EDTA Congress
- Place of Presentation
  Prague, Czech Rep
- Data Source
  KAKENHI-PROJECT-21591018
[Presentation] Design of redox imaging nanoprobe using nitroxyl radical containing nanoparticle2010
- Author(s)
  Yoshitomi T, Mamiya T, Matsui H, Hirayama A ,Nagasaki Y
- Organizer
  SFRBM 2010-17th Annual Meeting of the Society for Free Radical Biology and Medicine
- Place of Presentation
  Orlando, Florida
- Data Source
  KAKENHI-PROJECT-21591018
[Presentation] Novel Nanosphere Theranostic for Anti-Oxidative Stress2010
- Author(s)
  Nagasaki Y
- Organizer
  THE 1st INTERNATIONAL CONFERENCE FOR GREEN TECHNOLOGIES
- Place of Presentation
  Ajou University, Suwon, Korea
- Year and Date
  2010-02-06
- Data Source
  KAKENHI-PROJECT-21591018
[Presentation] Design of nitroxyl radicals containing nanoparticle for MR imaging of tumor2010
- Author(s)
  Yoshitomi T, Matsumoto S, Krishna MC, Matsumoto K, Anzai K, Matsui H, Hirayama A, Nagasaki Y
- Organizer
  The 37th Annual Meeting and Exposition of the Controlled Release Society
- Place of Presentation
  Oregon Convention Center, Portland, Oregon, USA.
- Data Source
  KAKENHI-PROJECT-21591018
[Presentation] Development of a pH-Sensitive Reno-Protective Nano-Particle for Relief of Ischemia-Reperfusion Acute Kidney Injury2010
- Author(s)
  Hirayama A, Yoshitomi T, Owada S, Ueda A, Matsui H, Aoyagi K, Nagasaki Y
- Organizer
  43rd Annual meeting of the American Society of Nephrology (Renal Week 2010)
- Place of Presentation
  Denver (abstract in J Am Soc Nephrol)
- Data Source
  KAKENHI-PROJECT-21591018
[Presentation] 反応性イメージングを目指したニトロキシルラジカル含有ナノ粒子の設計と評価2010
- Author(s)
  吉冨徹、間宮孝、松井裕史、平山暁、長崎幸夫
- Organizer
  第26回日本DDS学会学術集会
- Place of Presentation
  大阪国際交流センター
- Data Source
  KAKENHI-PROJECT-21591018
[Presentation] pH応答性TEMPO含有ナノ粒子のマウス急性腎不全モデルに対する保護効果2010
- Author(s)
  平山暁
- Organizer
  第22回腎とフリーラジカル研究会
- Place of Presentation
  町村会館(東京)
- Year and Date
  2010-10-16
- Data Source
  KAKENHI-PROJECT-21591018
[Presentation] Design of pH-sensitive polymeric micelle possessing reduced forms of TEMPO for imaging of ROS2010
- Author(s)
  Yoshitomi T, Mamiya T, Matsui H, Hirayama A, Nagasaki Y
- Organizer
  Young Investigator's Award winning presentation
- Place of Presentation
  Oxygen Club California World Congress, Santa Barbara, CA, USA.
- Data Source
  KAKENHI-PROJECT-21591018
[Presentation] Development of a pH-Sensitive Reno-Protective Nano-Particle for Relief of Ischemia-Reperfusion Acute Kidney Injury.2010
- Author(s)
  Hirayama A
- Organizer
  43rd Annual meeting of the American Society of Nenhroloev (Renal Week 2010)
- Place of Presentation
  Colorado Convention Center (Denver, CO)
- Data Source
  KAKENHI-PROJECT-21591018
[Presentation] Healing of Oxidative Stress in Brain on the Occasion of Cerebral Ischemia-Reperfusion.2009
- Author(s)
  Yoshitomi T, Toh K, Marushima A, Suzuki K, Tsurushima H, Hirayama A, Matsumura A, Nagasaki Y
- Organizer
  2009 Gordon Research Conference on Biomaterials: Biocompatibility and Tissue Engineering
- Place of Presentation
  Plymouth (USA)
- Data Source
  KAKENHI-PROJECT-21591018
[Presentation] Development of TEMPOL-Containing Nano-Particle for Continuous Superoxide Scavenging and Antihypertension2009
- Author(s)
  Hirayama A
- Organizer
  42nd Annual meeting of the American Society of Nephrology(Renal Week 2009)
- Place of Presentation
  San Diego, California, United States of America
- Year and Date
  2009-10-30
- Data Source
  KAKENHI-PROJECT-21591018
[Presentation] ラジカル含有ナノ粒子を用いた脳虚血-再潅流モデルラットにおける脳梗塞の抑制2009
- Author(s)
  藤加珠子、吉冨徹、丸島愛樹、鈴木謙介、鶴嶋英夫、平山暁、松村明、長崎幸夫
- Organizer
  第62回日本酸化ストレス学会学術集会
- Place of Presentation
  福岡ポスターアワード(優秀演題賞)受賞演題)
- Data Source
  KAKENHI-PROJECT-21591018
[Presentation] 生体内ROSの可視化を目指したEPRナノプローブの創製2009
- Author(s)
  吉冨徹、間宮孝、松井裕史、平山暁、長崎幸夫
- Organizer
  第62回日本酸化ストレス学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2009-06-11
- Data Source
  KAKENHI-PROJECT-21591018
[Presentation] Stable Radical-containing Nanoparticles for Anti-oxydative Stress Disease2009
- Author(s)
  Nagasaki Y
- Organizer
  FBPS2009
- Place of Presentation
  Mishima
- Year and Date
  2009-05-20
- Data Source
  KAKENHI-PROJECT-21591018
[Presentation] TEMPO含有ナノ粒子の開発と生体内動態2009
- Author(s)
  吉冨徹、平山暁、間宮孝、松井裕史、長崎幸夫
- Organizer
  第48回電子スピンサイエンス学会年会(SEST2009)
- Place of Presentation
  神戸
- Year and Date
  2009-11-12
- Data Source
  KAKENHI-PROJECT-21591018
[Presentation] Development of TEMPOL-Containing Nano-Particle for Continuous Superoxide Scavenging and Antihypertension.2009
- Author(s)
  Hirayama A, Yoshitomi T, Ueda A, Matsui H, Owada S, Aoyagi K, Nagasaki Y
- Organizer
  42nd Annual meeting of the American Society of Nephrology (Renal Week 2009)
- Place of Presentation
  San Diego
- Data Source
  KAKENHI-PROJECT-21591018
[Presentation] 安定した抗酸化・降圧効果を発揮するナノ粒子化TEMPOの開発2009
- Author(s)
  平山暁,吉冨徹,植田敦志,青柳一正,長崎幸夫
- Organizer
  第52回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2009-06-03
- Data Source
  KAKENHI-PROJECT-21591018
[Presentation] In vivo EPR analysis and imaging of antihypertensive drugs on renal reducing activity.2007
- Author(s)
  Hirayama A.
- Organizer
  EPR 2007: A Joint Conference of 12th In Vivo EPR Spectroscopy and Imaging 9th International EPR Spin Trapping/Spin Labeling
- Place of Presentation
  シカゴ(米国)
- Year and Date
  2007-04-30
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590878
[Presentation] In vivo EPR analysis and imaging of antihypertensive drugs on renal reducing activity2007
- Author(s)
  Hirayama A.
- Organizer
  EPR 2007: A Joint Conference of 12th In Vivo EPR Spectroscopy and Imaging 9th International EPR Spin Trapping/ Spin Labeling
- Place of Presentation
  Chicago, USA
- Year and Date
  2007-04-30
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590878
[Presentation] Imbalance of Mitochondrial Superoxide and Intracellular Nitric Oxide in the Hyperproteinuric Phase of Puromycin Nephrosis.2007
- Author(s)
  Hirayama A.
- Organizer
  40th annual meeting of the American Society of Nephrology
- Place of Presentation
  サンフランシスコ(米国)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590878
[Presentation] Ketsueki Touseki no Kousanka-teki Sokumen (Antioxidataive Effects of Hemodialysis), Workshop: Oxidative Stress in Dialysis Patients, UP to DATE2007
- Author(s)
  Hirayama A.
- Organizer
  52nd Annual Meeting of Japanese Society for Dialysis Therapy
- Place of Presentation
  Osaka
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590878
[Presentation] Imbalance of Mitochondrial Superoxide and Intracellular Nitric Oxide in the Hyperproteinuric Phase of Puromycin Nephrosis2007
- Author(s)
  Hirayama A.
- Organizer
  40th annual meeting of the American Society of Nephrology
- Place of Presentation
  San Francisco, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590878
[Presentation] 血液透析の抗酸化的側面ワークショップ「透析患者の酸化ストレスUp to date」2007
- Author(s)
  平山暁
- Organizer
  第52回日本透析医学会総会・学術集会
- Place of Presentation
  大阪
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590878
[Presentation] Upper Stream Reactions of Oxidative Stress in Hemodialysis Patients.
- Author(s)
  Hirayama A, Ueda A, Nagase S, Matsui H, Aoyagi K, Owada S.
- Organizer
  2013 Annual meeting of the American Society of Nephrology (Kidney Week 2013)
- Place of Presentation
  Georgia World Congress Center, Atlanta, GA, USA
- Data Source
  KAKENHI-PROJECT-24591224
[Presentation] 抗炎症性と老廃物吸着能を併せ持つシリカ含有レドックスナノ粒子の設計腹膜透析へ展開
- Author(s)
  松村卓馬, 矢口達也,池田豊, 吉冨徹,植田敦志,平山暁,長崎幸夫
- Organizer
  つくば医工連携フォーラム2014
- Place of Presentation
  つくば国際会議場，つくば
- Data Source
  KAKENHI-PROJECT-24591224
[Presentation] 高性能な腹膜透析液の開発を目指したシリカ含有レドックスナノ粒子の作製と評価
- Author(s)
  松村卓馬、矢口達也、池田豊、吉冨徹、平山暁、植田敦志 ,植田敦志、長崎幸夫
- Organizer
  第23回日本MRS年次大会
- Place of Presentation
  横浜開港記念会館，横浜情報文化センター，波止場会館，万国橋会議センター，横浜
- Data Source
  KAKENHI-PROJECT-24591224
[Presentation] Design of redox polymer-silica nanohybrid materials for effective treatment of renal failure.
- Author(s)
  Matsumura T, Yaguchi T, Yoshitomi T, Ikeda Y, Ueda A, Hirayama A, Nagasaki Y
- Organizer
  SPSJ International Polymer Conferences 2014
- Place of Presentation
  EPHOCAL Tsukuba (Tsukuba, Ibaraki, Japan)
- Year and Date
  2014-12-02 – 2014-12-04
- Data Source
  KAKENHI-PROJECT-24591224
[Presentation] Novel redox polymer therapeutics for antioxidative injuries
- Author(s)
  Nagasaki Y
- Organizer
  17th Biennial Meeting of Society for Free Radical Research International (SFRRI 2014)
- Place of Presentation
  Kyoto International Conference Center, Sakyo-ku, Kyoto
- Invited
- Data Source
  KAKENHI-PROJECT-24591224
[Presentation] Nanotechnology in, vivo: Redox Polymer Therapeutics
- Author(s)
  Nagasaki Y
- Organizer
  40th Annual Meeting & Exposition of the Controlled Release Society
- Place of Presentation
  Hawaii Convention Center, Honolulu, Hawaii, U.S.A
- Invited
- Data Source
  KAKENHI-PROJECT-24591224
[Presentation] Nano-kidney possessing oxidative stress suppression character.
- Author(s)
  Nagasaki Y, Yaguchi T, Matsumura T, Yoshitomi T, Ikeda Y, Ueda A, Hirayama A.
- Organizer
  ASN Kidney Week 2014, 2014 Annual Meeting of the American Society of Nephrology.
- Place of Presentation
  Philadelphia, PA (USA)
- Year and Date
  2014-11-13 – 2014-11-16
- Data Source
  KAKENHI-PROJECT-24591224

1. NAGASAKI Yukio (90198309)

# of Collaborated Projects: 2 results

# of Collaborated Products: 32 results
2. NAGASE Sohji (10189128)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. Miura Misa (30612014)

# of Collaborated Projects: 2 results

# of Collaborated Products: 20 results
4. 上月正博 (70234698)

# of Collaborated Projects: 2 results

# of Collaborated Products: 18 results
5. 植田敦志 (00708448)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
6. 丸島愛樹 (40722525)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
7. 鈴木謙介 (20400674)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
8. YABE Chihiro (70150571)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. IWATA Kazumi (60305571)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. KATSUYAMA Masato (60315934)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. KAKEHI Tomoko (20433279)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. YOSHITOMI Toru (20585799)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
13. MORITAKE Takashi (50450432)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. MATSUMOTO Yoshitaka (70510395)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. KOYAMA Akio (80111384)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. YANAKA Kiyoyuki (10312307)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. YOH Keigyou (90323302)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 松野邦晴 (50420708)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
19. 坪井康次 (90188615)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 伊藤修 (00361072)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
21. プエンテスサンドラ (00725765)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 鶴嶋英夫 (50315470)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
23. 滝川知司 (60450227)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
24. 松崎秀夫 (00334970)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 石川博 (30089784)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 赤池敏宏 (30101207)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 松丸祐司 (70323300)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 揚山直英 (50399458)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 池田豊 (70425734)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 井川正道 (60444212)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 岡沢秀彦 (50360813)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 米田誠 (70270551)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. OOWADA Shigeru

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
34. INOUE Yoshiaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. SHIMOJO Nobutake

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. OYANE Ayako

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
37. NAKAMURA Maki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. 河野了

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. 小山泰明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. 榎本有希

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
41. 西村千尋

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Hirayama Aki 平山 暁

HIRAYAMA Aki 平山 暁

Research Projects

Research Products

Co-Researchers

レドックスナノ粒子と口腔内間葉組織由来神経系細胞による脳梗塞急性期再生医療の開発Ongoing

Principal Investigator

Project Period (FY)

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Review Section

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Comprehensive PET imaging for oxidative stress and tau to clarify the pathogenesis of Alzheimer's diseaseOngoing

Principal Investigator

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Review Section

Research Institution

The bioenergetic dysfunction in ASD focusing on free radicalsOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of antioxidative mechanism of "Hojin-zai", a traditional Kampo medicine, and it application to the new prooxidant therapy.Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ナノ粒子化活性酸素消去剤による脳虚血再灌流障害の神経血管ユニット保護療法の開発Ongoing

Principal Investigator

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Effects of a renal rehabilitation exercise program in elderly patients with chronic renal falure

Principal Investigator

Project Period (FY)

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Research Institution

Renal rehabilitation program oriented to oxidative stress controlPrincipal Investigator

Principal Investigator

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Research Institution

Electron spin resonance live imaging for the metabolism and migration of radio-resistant brain tumor cells

Principal Investigator

Project Period (FY)

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Research Institution

Development of functional redox nanoparticle for long-term peritoneal dialysisPrincipal Investigator

Principal Investigator

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Research Institution

Development of an antioxidative nano-particle for redox sensoring and reno-protectionPrincipal Investigator

Principal Investigator

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Research Institution

Study on roles of a novel NADPH oxidase isoform in the development of lifestyle related diseases

Principal Investigator

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Non-invasive Redox Imaging for the Pathophysiological Analysis of Hypertensive Renal Disease and Development of Antioxidative TherapyPrincipal Investigator

Principal Investigator

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Research Institution

腎疾患における生体内酸化ストレス動態の非侵襲的画像化解析と抗酸化療法への応用Principal Investigator

Principal Investigator

Project Period (FY)

Hirayama Aki 平山暁

HIRAYAMA Aki 平山暁

[Book] 腎とフリーラジカル第7集・ESRイメージングによる腎抗酸化能変化のin vivo無侵襲定量解析法の確立とエリスロポエチンによる臓器保護効果測定への応用2004

[Journal Article] 症例鼻出血で発症した海綿静脈洞部内頚動脈解離性動脈瘤の1例2018