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Hirayama Aki  平山 暁

… Alternative Names

HIRAYAMA Aki  平山 暁

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Researcher Number 20323298
Other IDs
  • ORCIDhttps://orcid.org/0000-0001-5777-4208
Affiliation (Current) 2020: 筑波技術大学, 保健科学部, 教授
Affiliation (based on the past Project Information) *help 2009 – 2020: Tsukuba University of Technology, 保健科学部, 教授
2010: 筑波技術大学, 保健科学部, 特任教授
2007 – 2008: Tsukuba University of Technology, Faculty of Health Sceinces, Professor
2006: 筑波大学, 大学院人間総合科学研究科, 講師
2004: 筑波大学, 大学院・人間総合科学研究科, 講師
2001 – 2003: 筑波大学, 臨床医学系, 講師
Review Section/Research Field
Principal Investigator
Kidney internal medicine / Kidney internal medicine / Rehabilitation science/Welfare engineering / Basic Section 52010:General internal medicine-related
Except Principal Investigator
Neurosurgery / General pharmacology / Kidney internal medicine / Applied health science / Medium-sized Section 9:Education and related fields / Basic Section 56010:Neurosurgery-related / Basic Section 52020:Neurology-related
Keywords
Principal Investigator
酸化ストレス / 電子スピン共鳴 / Nrf2 / ナノ粒子 / 慢性腎臓病 / ループス腎炎 / Carbamoyl-PROXYL / 一酸化窒素 / リポポリサッカライド / ESRイメージング … More / in vivo ESR / Nrf2遺伝子欠損マウス / 抗酸化能 / フリーラジカル / ESR(EPR)イメージング / スピンプローブ / 虚血再潅流急性腎不全 / 糖尿病性腎症 / phosphatidylcholine hydroperoxide / 急性腎障害 / ドラッグデリバリーシステム / 腎保護薬 / TEMPO / DDS(Drug Delivery System) / ナノメディシン / 腹膜透析 / 硬化性被嚢性腹膜炎 / 高血圧 / 高血圧性腎障害 / カルシウム拮抗薬 / アンジオテンシンレセプター拮抗薬 / Electron Paramagnetic Resonance / Electron Paramagnetic Resonance Imaging / Hypertension / Ca Channel Antagonist / Angiotensin II Receptor Antagonist / Oxidative Stress / 腎臓リハビリテーション / 血液透析 / 運動療法 / 多種ラジカル消去活性(MULTIS) / QOL / 牛車腎気丸 / 補腎剤 / MULTIS / 漢方 / 東洋医学 … More
Except Principal Investigator
脳梗塞 / フリーラジカル / 酸化ストレス / 糖尿病 / 循環器・高血圧 / シグナル伝達 / 薬理学 / Electron Spin Resonance / Cancer Stem Cell / Cell Cycle / Radiation / 脳腫瘍額 / 癌幹細胞 / 電子スピン共鳴 / がん幹細胞 / 細胞周期 / 遮光透析 / 紫外線除去フィルム / ダイアライザー / 血中過酸化脂質 / 1重項酸素 / 内皮型NOS / NO過剰産生 / ウサギの遮光透析モデル / 光遮断血液回路 / UVカット透析 / 一酸化窒素 / 過酸化脂質 / TBARS / PCOOH / 抗酸化能 / LIGHT SHIELDED HEMODIALYSIS / ULTRAVIOLET CUT FILM / DIALYZER / PLASMA LIPID PEROXIDES / SINGLET OXYGEN / ENDOTHELIAL NOS / NO OVERPRODUCTION / RABBIT MODEL OF LIGHT SHIELDED HEMODIALYSIS / 高齢者 / 慢性腎不全 / 血液透析 / 透析中の運動 / 運動様式 / 運動耐容能 / 筋力 / 生化学変化 / 維持透析 / 透析中の運動療法 / 透析中の電気刺激 / 安全性 / 有効性 / 身体運動機能 / 生化学検査 / 外来透析 / 負荷量可変型エルゴメータ / 電動式エルゴメータ / RCT / 慢性腎不全患者 / 血液透析患者 / 腎臓リハビリテーション / 電動アシスト自転車 / 負荷量可変型自転車 / 透析効率 / RNP / 脳虚血再灌流障害 / 血栓回収療法 / 神経血管ユニット保護 / 血液脳関門 / ナノ粒子化活性酸素消去剤 / 脳神経外科学 / 脳血管障害学 / 自閉症 / 社会性 / レドックスナノ粒子 / 口腔内間葉組織由来神経系細胞 / 細胞認識性カドヘリンマトリックス / 神経再生 / アルツハイマー病 / タウ / PETイメージング / 認知症 Less
  • Research Projects

    (15 results)
  • Research Products

    (109 results)
  • Co-Researchers

    (41 People)
  •  レドックスナノ粒子と口腔内間葉組織由来神経系細胞による脳梗塞急性期再生医療の開発Ongoing

    • Principal Investigator
      丸島 愛樹
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      University of Tsukuba
  •  Comprehensive PET imaging for oxidative stress and tau to clarify the pathogenesis of Alzheimer's diseaseOngoing

    • Principal Investigator
      井川 正道
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      University of Fukui
  •  The bioenergetic dysfunction in ASD focusing on free radicalsOngoing

    • Principal Investigator
      松崎 秀夫
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 9:Education and related fields
    • Research Institution
      University of Fukui
  •  Analysis of antioxidative mechanism of "Hojin-zai", a traditional Kampo medicine, and it application to the new prooxidant therapy.Principal InvestigatorOngoing

    • Principal Investigator
      平山 暁
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Tsukuba University of Technology
  •  ナノ粒子化活性酸素消去剤による脳虚血再灌流障害の神経血管ユニット保護療法の開発Ongoing

    • Principal Investigator
      丸島 愛樹
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurosurgery
    • Research Institution
      University of Tsukuba
  •  Effects of a renal rehabilitation exercise program in elderly patients with chronic renal falure

    • Principal Investigator
      Miura Misa
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied health science
    • Research Institution
      Tsukuba University of Technology
  •  Renal rehabilitation program oriented to oxidative stress controlPrincipal Investigator

    • Principal Investigator
      Hirayama Aki
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Rehabilitation science/Welfare engineering
    • Research Institution
      Tsukuba University of Technology
  •  Electron spin resonance live imaging for the metabolism and migration of radio-resistant brain tumor cells

    • Principal Investigator
      MORITAKE Takashi
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Neurosurgery
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  Development of functional redox nanoparticle for long-term peritoneal dialysisPrincipal Investigator

    • Principal Investigator
      AKI HIRAYAMA
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Tsukuba University of Technology
  •  Development of an antioxidative nano-particle for redox sensoring and reno-protectionPrincipal Investigator

    • Principal Investigator
      HIRAYAMA Aki
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Tsukuba University of Technology
  •  Study on roles of a novel NADPH oxidase isoform in the development of lifestyle related diseases

    • Principal Investigator
      YABE Chihiro
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Non-invasive Redox Imaging for the Pathophysiological Analysis of Hypertensive Renal Disease and Development of Antioxidative TherapyPrincipal Investigator

    • Principal Investigator
      HIRAYAMA Aki
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Tsukuba University of Technology
      University of Tsukuba
  •  腎疾患における生体内酸化ストレス動態の非侵襲的画像化解析と抗酸化療法への応用Principal Investigator

    • Principal Investigator
      平山 暁
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Kidney internal medicine
    • Research Institution
      University of Tsukuba
  •  Development of New Method of Hemodialysis Using Light Shielded Dialyzer and Blood Circuit

    • Principal Investigator
      NAGASE Sohji
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      University of Tsukuba
  •  in vivo 3次元ESRによる腎疾患モデル動物の生体内酸化・抗酸化動態解析Principal Investigator

    • Principal Investigator
      平山 暁
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Kidney internal medicine
    • Research Institution
      University of Tsukuba

All 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation Book Patent

  • [Book] Application of EPR Imaging to the Pathophysiological Analysis of Acute Renal Failure and Antioxidative Effects of Erythropoietin. In The Proceedings of the 12th Biennial Meeting of the Society for Free Radical Research International.2005

    • Author(s)
      Hirayama A.et al.(edited by Boveris A.et al.)
    • Total Pages
      395
    • Publisher
      Medimond S.r.l.(Bologna, Italy)
    • Data Source
      KAKENHI-PROJECT-15790427
  • [Book] 腎とフリーラジカル 第7集・ESRイメージングによる腎抗酸化能変化のin vivo無侵襲定量解析法の確立とエリスロポエチンによる臓器保護効果測定への応用2004

    • Author(s)
      平山 暁 他
    • Total Pages
      190
    • Publisher
      東京医学社・東京
    • Data Source
      KAKENHI-PROJECT-15790427
  • [Journal Article] The visualization methods of occluded dural sinus for safe transvenous embolization of dural AVFs2019

    • Author(s)
      Hosoo H, Tsuruta W, Nakai Y, Shiigai M, Sato M, Ito Y, Takigawa T, Marushima A, Ishikawa E, Yamamoto T, Matsumaru Y, Matsumura A.
    • Journal Title

      World Neurosurgery

      Volume: 印刷中

    • DOI

      10.1016/j.wneu.2019.02.250

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10819
  • [Journal Article] 症例 鼻出血で発症した海綿静脈洞部内頚動脈解離性動脈瘤の1例2018

    • Author(s)
      Kino H, Tsuruta W, Ito Y, Takigawa T, Shiigai M, Marushima A, Nakai Y, Yamamoto T, Matsumura A
    • Journal Title

      Neurological Surgery 脳神経外科

      Volume: 46 Issue: 9 Pages: 789-795

    • DOI

      10.11477/mf.1436203815

    • ISSN
      0301-2603, 1882-1251
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10819
  • [Journal Article] Improving the neurological prognosis following OHCA using real-time evaluation of cerebral tissue oxygenation2018

    • Author(s)
      Koyama Y, Inoue Y, Hisago S, Marushima A, Hagiya K, Yamasaki Y, Enomoto Y, Shimojo N, Kawano S, Mizutani T
    • Journal Title

      American Journal of Emergency Medicine

      Volume: 36

    • DOI

      10.1016/j.ajem.2017.11.029

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10819, KAKENHI-PROJECT-17K19787, KAKENHI-PROJECT-17K17623
  • [Journal Article] Clinical significance of redox effects of Kampo formulae, a traditional Japanese herbal medicine: comprehensive estimation of multiple antioxidative activities2018

    • Author(s)
      Hirayama Aki、Oowada Shigeru、Ito Hiromu、Matsui Hirofumi、Ueda Atsushi、Aoyagi Kazumasa
    • Journal Title

      J. Clin. Biochem. Nutr.

      Volume: 62 Issue: 1 Pages: 39-48

    • DOI

      10.3164/jcbn.17-59

    • NAID

      130006301228

    • ISSN
      0912-0009, 1880-5086
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K12575
  • [Journal Article] Preliminary in vivo magnetofection data using magnetic calcium phosphate nanoparticles immobilizing DNA and iron oxide nanocrystals2018

    • Author(s)
      Shubhra Quazi T.H.、Oyane Ayako、Nakamura Maki、Puentes Sandra、Marushima Aiki、Tsurushima Hideo
    • Journal Title

      Data in Brief

      Volume: 18 Pages: 1696-1701

    • DOI

      10.1016/j.dib.2018.04.058

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10819, KAKENHI-PROJECT-16H03831
  • [Journal Article] Spinal Cord Infarction in the Region of the Posterior Spinal Artery After Embolization for Vertebral Artery Dissection2018

    • Author(s)
      Tsuruta Wataro、Yamamoto Tetsuya、Ikeda Go、Sato Masayuki、Ito Yoshiro、Takigawa Tomoji、Marushima Aiki、Nakai Yasunobu、Matsumaru Yuji、Matsumura Akira
    • Journal Title

      Operative Neurosurgery

      Volume: 15 Pages: 701-710

    • DOI

      10.1093/ons/opy026

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10819
  • [Journal Article] Treatment Strategy Based on Plaque Vulnerability and the Treatment Risk Evaluation for Internal Carotid Artery Stenosis2018

    • Author(s)
      ITO Yoshiro、TSURUTA Wataro、NAKAI Yasunobu、TAKIGAWA Tomoji、MARUSHIMA Aiki、MASUMOTO Tomohiko、MATSUMARU Yuji、ISHIKAWA Eiichi、MATSUMURA Akira
    • Journal Title

      Neurologia medico-chirurgica

      Volume: 58 Issue: 5 Pages: 191-198

    • DOI

      10.2176/nmc.oa.2017-0228

    • NAID

      130006734354

    • ISSN
      0470-8105, 1349-8029
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10819
  • [Journal Article] Intensive Gait Treatment Using a Robot Suit Hybrid Assistive Limb in Acute Spinal Cord Infarction: Report of Two Cases2017

    • Author(s)
      Watanabe H, Marushima A, Kawamoto H, Kadone H, Ueno T, Shimizu Y, Endo A, Hada Y, Saotome K, Abe T, Yamazaki M, Sankai Y, Ishikawa E, Matsumura A
    • Journal Title

      J Spinal Cord Med

      Volume: 9 Pages: 1-7

    • DOI

      10.1080/10790268.2017.1372059

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10819
  • [Journal Article] Combination Therapy with Peritoneal Dialysis and Hemodialysis from the Initiation of Renal Replacement Therapy Preserves Residual Renal Function and Serum Albumin.2017

    • Author(s)
      A Ueda, K Nagai, A Hirayama, C Saito, K Yamagata
    • Journal Title

      Advances in peritoneal dialysis

      Volume: 33 Pages: 74-78

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K12575
  • [Journal Article] Nurovascular unit protection from cerebral ischemia-reperfusion injury by radical-containing nanoparticles in mice2017

    • Author(s)
      Hosoo H, Marushima A, Nagasaki Y, Hirayama A, Ito H, Puentes S, Mujagic A, Tsurushima H, Tsuruta W, Suzuki K, Matsui H, Matsumaru Y, Yamamoto T, Matsumura
    • Journal Title

      Stroke

      Volume: 48 Pages: 2238-2247

    • DOI

      10.1161/strokeaha.116.016356

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10819, KAKENHI-PROJECT-25220203, KAKENHI-PROJECT-16K15628
  • [Journal Article] Training with an Electric Exercise Bike versus a Conventional Exercise Bike during Hemodialysis for Patients with End-stage Renal Disease: A Randomized Clinical Trial2017

    • Author(s)
      Miura M, Yoshizawa R, Oowada S, Hirayama A, Ito O, Kohzuki M, Maeba T.
    • Journal Title

      PRM

      Volume: 2 Issue: 0 Pages: 20170008-20170008

    • DOI

      10.2490/prm.20170008

    • NAID

      130007042064

    • ISSN
      2432-1354
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H02118, KAKENHI-PROJECT-15K01702, KAKENHI-PROJECT-15K12575
  • [Journal Article] Exercise Program for Chronic Kidney Disease Improves Pathophysiological Condition with a Shift of Oxidative Stress2017

    • Author(s)
      Hirayama Aki、Miura Misa、Yasuda Go、Nagano Yumiko、Matsui Hirofumi、Hirayama Yoh、Ueda Atsushi、Aoyagi Kazumasa、Kohzuki Masahiro、Oowada Shigeru
    • Journal Title

      Free Radical Biology and Medicine

      Volume: 112 Pages: 131-132

    • DOI

      10.1016/j.freeradbiomed.2017.10.200

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K12575
  • [Journal Article] 視覚障害学生に対する喀痰吸引モデル使用の経験2017

    • Author(s)
      三浦美佐,上月正博,松下昌之助,平山暁,石塚和重
    • Journal Title

      ロービジョン学会誌

      Volume: 1 Pages: 1-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K01702
  • [Journal Article] 2015 国際学会報告2016

    • Author(s)
      三浦美佐,平山 暁,大和田滋,前波輝彦,小川佳子,伊藤 修,上月正博
    • Journal Title

      筑波技術大学テクノレポート

      Volume: 23(2) Pages: 50-53

    • Data Source
      KAKENHI-PROJECT-15K01702
  • [Journal Article] 理学療法士による運動とその効果.CKD患者のサルコペニア・フレイル2016

    • Author(s)
      三浦美佐,平山暁
    • Journal Title

      腎と透析

      Volume: 80.5 Pages: 745-750

    • Data Source
      KAKENHI-PROJECT-15K01702
  • [Journal Article] Effects of a renal rehabilitation exercise program in patients with CKD: Controlled trial.2015

    • Author(s)
      Miura M, Hirayama A, Oowada S, Ito O, Kohzuki M.
    • Journal Title

      F1000 Research

      Volume: 1 Pages: 421-421

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K01702
  • [Journal Article] Design and use of silica-containing redox nanoparticles, siRNPs, for high-performance peritoneal dialysis2014

    • Author(s)
      Yukio Nagasaki, Tatsuya Yaguchi, Takuma Matsumura, Toru Yoshitomi, Yutaka Ikeda, Atsushi Ueda, and Aki Hirayama
    • Journal Title

      Biomaterials Science

      Volume: 2 Pages: 522-528

    • DOI

      10.1039/c3bm60236b

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-13J06119, KAKENHI-PROJECT-24591224, KAKENHI-PUBLICLY-25107707, KAKENHI-PROJECT-25220203
  • [Journal Article] Reactive Oxygen Species-Scavenging Nanomedicines for the Treatment of Oxidative Stress Injuries2014

    • Author(s)
      Toru Yoshitomi, Yukio Nagasaki
    • Journal Title

      Advanced Healthcare Materials

      Volume: 3 Pages: 1149-1161

    • DOI

      10.1002/adhm.201300576

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-13J06119, KAKENHI-PROJECT-24591224, KAKENHI-PROJECT-25220203
  • [Journal Article] Redox-active Injectable Gel Using Thermo-responsive Nanoscale Polyion Complex Flower Micelle for Noninvasive Treatment of Local Inflammation,2013

    • Author(s)
      Pua ML, Yoshitomi T, Chonpathompikunlert P, Hirayama A, Nagasaki Y
    • Journal Title

      Journal of Controlled Release

      Volume: 172 Pages: 914-920

    • DOI

      10.1016/j.jconrel.2013.10.009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591224, KAKENHI-PROJECT-24659920, KAKENHI-PUBLICLY-25107707, KAKENHI-PROJECT-25220203
  • [Journal Article] The ROS scavenging and renalprotective effects of pH-responsive nitroxide radical containingnanoparticles.2011

    • Author(s)
      Toru Yoshitomi, Aki Hirayama, Yukio Nagasaki
    • Journal Title

      Biomaterials

      Volume: 32 Pages: 8021-8

    • DOI

      10.1016/j.biomaterials.2011.07.014

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21240050, KAKENHI-PROJECT-21591018, KAKENHI-PROJECT-22659008
  • [Journal Article] Newly Synthesized Radical-containing Nanoparticles (RNP) Enhance Neuroprotection after Cerebral Ischemia-reperfusion Injury2011

    • Author(s)
      Aiki Marushima, Hideo Tsurusima, Toru Yoshitomi, Kazuko Toh, Aki Hirayama, Yukio Nagasaki, Akira Matumura
    • Journal Title

      Neurosurgery

      Volume: 68 Pages: 1418-1426

    • DOI

      10.1227/neu.0b013e31820c02d9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21240050, KAKENHI-PROJECT-21591018, KAKENHI-PROJECT-22800004
  • [Journal Article] Development of a pH-Sensitive Reno-Protective Nano-Particle for Relief of Ischemia-Reperfusion Acute Kidney Injury.2010

    • Author(s)
      Hirayama A
    • Journal Title

      Journal of American Society of Nephrology

      Volume: 21

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Journal Article] Spherical carbon adsorbent (AST-120) protects deterioration of renal function in chronic kidney disease rats through inhibition of reactive oxygen species production from mitochondria and reduction of serum lipid peroxidation2010

    • Author(s)
      Owada S, Maeba T, Sugano Y, Hirayama A, Ueda A, Nagase S, Goto S, Nishijima F, Bannai K, Yamato H
    • Journal Title

      Nephron Exp Nephrol

      Volume: 115(4)

    • Data Source
      KAKENHI-PROJECT-21591018
  • [Journal Article] pH-Sensitive Radical.Containing-Nanoparticle (RNP) for theL-Band-EPR Imaging of Low pH Circumstances2009

    • Author(s)
      Yoshitomi T, Suzuki R, Mamiya T, Matsui H, Hirayama A, Nagasaki Y.
    • Journal Title

      Bioconjugate Chem

      Volume: 20 Pages: 1792-1798

    • Data Source
      KAKENHI-PROJECT-21591018
  • [Journal Article] NADPH oxidase isoforms and anti-hypertensive effects of atorvastatin demonstrated in two animal models.2009

    • Author(s)
      Cui W, Matsuno K, Iwata K, Ibi M, Katsuyama M, Kakehi T, Sasaki M, Ikami K, Zhu K, Yabe-Nishimura C.
    • Journal Title

      J Pharmacol Sci 111

      Pages: 260-268

    • NAID

      10026154161

    • Data Source
      KAKENHI-PROJECT-20390071
  • [Journal Article] In vivo imaging of renal redox status during azelnidpine treatments2008

    • Author(s)
      Hirayama A.
    • Journal Title

      Hypertension Research (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590878
  • [Journal Article] In vivo imaging of renal redox status during azelnidpine treatments2008

    • Author(s)
      Hirayama A.
    • Journal Title

      Hypertension Research (印刷中)

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590878
  • [Journal Article] The AP-1 site is essential for the promoter activity of NOX1/NADPH oxidase, a vascular superoxide-producing enzyme : Possible involvement of the ERK1/2-JunB pathway.2008

    • Author(s)
      Cevik MO, Katsuyama M, Kanda S, Kaneko T, Iwata K, Ibi M, Matsuno K, Kakehi T, Cui W, Sasaki M, Yabe-Nishimura C.
    • Journal Title

      Biochem Biophys Res Commun 374

      Pages: 351-355

    • Data Source
      KAKENHI-PROJECT-20390071
  • [Journal Article] Renal redox imaging and in vivo analysis during antihypertensive treatments.2006

    • Author(s)
      Hirayama A
    • Journal Title

      Nephrology Dialysis Transplantation 21・Suppl.4

      Pages: 41-42

    • Data Source
      KAKENHI-PROJECT-18590878
  • [Journal Article] Electron paramagnetic resonance imaging of oxidative stress in renal disease.2006

    • Author(s)
      Hirayama A
    • Journal Title

      Nephron Clinical Practice 103

    • Data Source
      KAKENHI-PROJECT-18590878
  • [Journal Article] In vivo imaging of oxidative stress in ischemia-reperfusion renal injury using electron paramagnetic resonance.2005

    • Author(s)
      Hirayama A. et al.
    • Journal Title

      American Journal of Physiology Renal Physiology 208・3

    • Data Source
      KAKENHI-PROJECT-15790427
  • [Journal Article] EPR imaging of reducing activity in Nrf2 transcriptional factor deficient mice.2003

    • Author(s)
      Hirayama A. et al.
    • Journal Title

      Free Radical Biology & Medicine 34・10

      Pages: 1236-1242

    • Data Source
      KAKENHI-PROJECT-15790427
  • [Journal Article] Oxidative stress during leukocyte absorption apheresis2003

    • Author(s)
      Hirayama A. et al.
    • Journal Title

      Journal of Clinical Apheresis 18・2

      Pages: 61-66

    • Data Source
      KAKENHI-PROJECT-15790427
  • [Journal Article] Electron paramagnetic resonance imaging of nitric oxide organ distribution in lipopolysuccaride treated mice2003

    • Author(s)
      Hirayama A. et al.
    • Journal Title

      Molecular and Cellular Biochemistry 244・1

      Pages: 63-67

    • Data Source
      KAKENHI-PROJECT-15790427
  • [Patent] 高分子環状ニトロキシドラジカル化合物とシリカの有機―無機ハイブリッド複合体2013

    • Inventor(s)
      長崎幸夫,吉冨 徹,平山 暁他
    • Industrial Property Rights Holder
      長崎幸夫,池田 豊,吉冨 徹,植田敦志,平山 暁,他
    • Industrial Property Rights Type
      特許
    • Filing Date
      2013-02-06
    • Overseas
    • Data Source
      KAKENHI-PROJECT-24591224
  • [Patent] 高分子環状ニトロキシドラジカル化合物とシリカの有機.無機ハイブリッド複合体2012

    • Inventor(s)
      長崎幸夫,吉冨徹,池田豊,植田敦志,平山暁,矢口達也,山下真代
    • Industrial Property Rights Holder
      国立大学法人筑波大学,国立大学法人筑波技術大学
    • Industrial Property Number
      2012-024460
    • Filing Date
      2012-02-07
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Patent] 高分子環状ニトロキシドラジカル化合物とシリカの有機-無機ハイブリッド複合体2012

    • Inventor(s)
      長崎幸夫, 吉冨徹, 池田豊, 植田敦志, 平山暁, 矢口達也, 山下真代
    • Industrial Property Rights Holder
      長崎幸夫, 吉冨徹, 池田豊, 植田敦志, 平山暁, 矢口達也, 山下真代および国立大学法人筑波大学国立大学法人筑波技術大学
    • Industrial Property Number
      2012-024460
    • Filing Date
      2012-02-07
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Patent] Polymerized cyclic nitro-xide radical compound, and use thereof2010

    • Inventor(s)
      NAGASAKI, Yukio. YOSHITOMI, Toru. MATSUI, Hirofumi. HIRAYAMA, Aki. MAMIYA, Takashi. MATSUMUR A, Akira. SUZUKI, Kensuke. TSURUSHIM A, Hideo. MARUSHIMA, Aiki. TOH, Kazuko MIYAMOTO, Daisuke
    • Industrial Property Rights Holder
      NAGASAKI, Yukio. YOSHITOMI, Toru. MATSUI, Hirofumi. HIRAYAMA, Aki. MAMIYA, Takashi. MATSUMUR A, Akira. SUZUKI, Kensuke. TSURUSHIM A, Hideo. MARUSHIMA, Aiki. TOH, Kazuko MIYAMOTO, DaisukeおよびUniversity of Tsukuba
    • Filing Date
      2010-11-02
    • Overseas
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Patent] Polymerized cyclic nitro-xide radical compound, and use thereof2010

    • Inventor(s)
      NAGASAKI, Yukio. YOSHITOMI, Toru. MATSUI, Hirofumi. HIRAYAMA, Aki. MAMIYA, Takashi. MATSUMUR A, Akira. SUZUKI, Kensuke. TSURUSHIM A, Hideo. MARUSHIMA, Aiki. TOH, Kazuko MIYAMOTO, Daisuke
    • Industrial Property Rights Holder
      NAGASAKI, Yukio. YOSHITOMI, Toru. MATSUI, Hirofumi. HIRAYAMA, Aki. MAMIYA, Takashi. MATSUMUR A, Akira. SUZUKI, Kensuke. TSURUSHIM A, Hideo. MARUSHIMA, Aiki. TOH, Kazuko MIYAMOTO, DaisukeおよびUniversity of Tsukuba
    • Filing Date
      2010-11-02
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Patent] Polymerized cyclic nitroxide radical compound, and use thereof2009

    • Inventor(s)
      NAGASAKI, Yukio. YOSHITOMI, Toru. MATSUI, Hirofumi. HIRAYAMA, Aki. MAMIYA, Takashi. MATSU-MURA, ra. SUZUKI, Kensuke. TSURUSHI-MA, Hideo. MARUSHI-MA, AiKi. TOH, Kazuko. MIYAMOTO, Daisuke
    • Industrial Property Rights Holder
      NAGASAKI, Yukio. YOSHITOMI, Toru. MATSUI, Hirofumi. HIRAYAMA, Aki. MAMIYA, Takashi. MATSU-MURA, ra. SUZUKI, Kensuke. TSURUSHI-MA, Hideo. MARUSHI-MA, AiKi. TOH, Kazuko. MIYAMOTO, Daisukeおよび University of Tsukuba
    • Filing Date
      2009-05-11
    • Overseas
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Patent] Polymerized cyclic nitroxide radical compound, and use thereof2009

    • Inventor(s)
      NAGASAKI Yukio, YOSHITOMI Toru, MATSUI Hirofumi, HIRAYAMA Aki,MAMIYA Takashi, MATSUMURA Akira, SUZUKI Kensuke, TSURUSHIMA Hideo,MARUSHIMA Aiki, TOH Kazuko, MIYAMOTO Daisuke
    • Industrial Property Rights Holder
      NAGASAKI Yukio, YOSHITOMI Toru, MATSUI Hirofumi, HIRAYAMA Aki, MAMIYA Takashi, MATSUMURA Akira, SUZUKI Kensuke, TSURUSHIMA Hideo, MARUSHIMA Aiki, TOH Kazuko, MIYAMOTO Daisuke, University of Tsukuba
    • Filing Date
      2009-05-11
    • Overseas
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Patent] Polymerized cyclic nitroxide radical compound, and use thereof2009

    • Inventor(s)
      NAGASAKI, Yukio. YOSHITOMI, Toru. MATSUI, Hirofumi. HIRAYAMA, Aki. MAMIYA, Takashi. MATSUMURA, Akira. SUZUKI, Kensuke. TSURUSHIMA, Hideo. MARUSHIMA, Aiki. TOH, Kazuko. MIYAMOTO, Daisuke
    • Industrial Property Rights Holder
      同左およびUniversity of Tsukuba
    • Filing Date
      2009-05-11
    • Overseas
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Presentation] 脳梗塞急性期再開通療法における環境応答性ナノ粒子化活性酸素消去剤(RNP)による脳保護療法の開発2018

    • Author(s)
      丸島愛樹、細尾久幸、長崎幸夫、Mujagic A、Puentes S、平山 暁、鈴木謙介、滝川知司、早川幹人、伊藤嘉朗、鶴嶋英夫、松井裕史、石川栄一、井上貴昭、松丸祐司、松村 明
    • Organizer
      第43回日本脳卒中学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K10819
  • [Presentation] 脳梗塞急性期血栓回収療法におけるナノ粒子化活性酸素消去剤(RNP)による脳保護療法の開発2018

    • Author(s)
      丸島愛樹、長崎幸夫、Mujagic A、高橋利英、渡部大輔、松村英明、Ting M、Puentes S、細尾久幸、平山 暁、鈴木謙介、滝川知司、石川栄一、井上貴昭、松丸祐司、松村 明
    • Organizer
      第61回日本脳循環代謝学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K10819
  • [Presentation] Long Term Renal Rehabilitation Induces a Significant Shift in Serum Antioxidative Profile.2018

    • Author(s)
      Hirayama A, Ueda A, Miura M, Yasuda G, Nishida A, Hirayama Y, Kohzuki M, Oowada S.
    • Organizer
      Annual Dialysis Conference 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K12575
  • [Presentation] 抗酸化ナノメディシン(RNP)による急性脳主幹動脈閉塞に対する脳保護療法の開発2018

    • Author(s)
      丸島愛樹、長崎幸夫、細尾久幸、Mujagic A、松村英明、渡部大輔、Puentes S、平山 暁、松井裕史、鈴木謙介、滝川知司、早川幹人、佐藤允之、伊藤嘉朗、石川栄一、井上貴昭、松丸祐司、松村 明
    • Organizer
      第33回日本酸化ストレス学会関東支部会
    • Data Source
      KAKENHI-PROJECT-17K10819
  • [Presentation] 毛細血管・赤血球の異常を再現したお血類似病態のライブイメージングと,駆お血剤による血流動態及び NO 産生効果の動画解析2018

    • Author(s)
      平山 暁,富田 勉,青柳 一正.
    • Organizer
      第69回日本東洋医学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07437
  • [Presentation] ライブイメージング技術の応用による駆お血剤薬理効果定量解析の試み2018

    • Author(s)
      平山 暁,富田 勉,青柳 一正.
    • Organizer
      第75回日本東洋医学会関東甲信越支部学術総会
    • Data Source
      KAKENHI-PROJECT-18K07437
  • [Presentation] ミニシンポジウム 「臨床現場でのESR応用」2018

    • Author(s)
      平山 暁
    • Organizer
      第57回電子スピンサイエンス学会(SEST2018)
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K07437
  • [Presentation] ナノ粒子化活性酸素消去剤(RNP)による神経保護療法の実用化を目指した研究開発2018

    • Author(s)
      丸島愛樹、長崎幸夫、Mujagic A、高橋利英、渡部大輔、松村英明、Ting M、Puentes S、細尾久幸、平山暁、鈴木謙介、滝川知司、石川栄一、井上貴昭、松丸祐司、松村 明
    • Organizer
      日本脳神経外科学会第77回学術総会
    • Data Source
      KAKENHI-PROJECT-17K10819
  • [Presentation] Neurovascular Unit Protection Using Nitroxide Radicals-containing Nanoparticles (TEMPO-RNP) for Cerebral Ischemia-reperfusion Injury in Mice2018

    • Author(s)
      Hisayuki Hosoo, Aiki Marushima, Yukio Nagasaki, Aki Hirayama, Hiromu Ito, Sandra Puentes, Arnela Mujagic, Hideo Tsurushima, Wataro, Kensuke Suzuki; Hirofumi Matsui, Yuji Matsumaru, Tetsuya Yamamoto, Akira Matsumura
    • Organizer
      International stroke conference 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10819
  • [Presentation] 活性酸素消去剤封入ナノ粒子(RNP)による脳虚血再灌流障害に対するNeurovascular unit保護効果2017

    • Author(s)
      丸島愛樹、細尾久幸、長崎幸夫、平山暁、Sandra Puentes、Arnela Mujagic 、伊藤紘、鶴嶋英夫、鶴田和太郎、鈴木謙介、松井裕史、松丸祐司、山本哲哉、松村明
    • Organizer
      第60回脳循環代謝学会
    • Data Source
      KAKENHI-PROJECT-17K10819
  • [Presentation] Exercise program for chronic kidney disease improves pathophysiological condition with a shift of oxidative stress.2017

    • Author(s)
      Hirayama A, Miura M, Yasuda G, Nagano Y, Matsui H, Hirayama Y, Ueda A, Aoyagi K, Kohzuki M, Oowada S.
    • Organizer
      The Society for Redox Biology and Medicine's 24th Annual Meeting (SfRBM 2017)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K12575
  • [Presentation] OXIDATIVE STRESS DURING RENAL REHABILITATION2017

    • Author(s)
      Hirayama A, Miura M, Hirayama Y, Nagano Y, Yasuda G, Ueda A, Matsui H, Aoyagi K, Kozuki M, Oowada S.
    • Organizer
      World Conference of Nephrology 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K12575
  • [Presentation] Redox nano-particle for peritoneal dialysis solution2017

    • Author(s)
      Hirayama A, Nagasaki Y, Yaguchi T, Matsumura T, Yoshitomi T, Ikeda Y, Ueda A.
    • Organizer
      Annual Dialysis Conference 2017
    • Place of Presentation
      Long Beach Convention Center, Long Beach, CA, USA
    • Year and Date
      2017-03-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K12575
  • [Presentation] 性腎臓病進行抑制のため自宅での電気刺激療法を試みた1症例2017

    • Author(s)
      三浦美佐,斎藤知栄,平山暁,伊藤修,上月正博,山縣邦弘
    • Organizer
      日本腎臓リハビリテーション学会
    • Data Source
      KAKENHI-PROJECT-15K01702
  • [Presentation] Advantages of nutrition counseling in CKD patients by a professional dietician on the physical or psychological state.2016

    • Author(s)
      Ueda A, Hirayama A, Yamagata K.
    • Organizer
      ASN Kidney Week 2016 Annual Meeting of the American Society of Nephrlogy
    • Place of Presentation
      McCormic Place, Chicago, IL., USA
    • Year and Date
      2016-11-15
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K12575
  • [Presentation] Effects of a renal rehabilitation exercise program in patients with end stage renal disease: study protocol for a multi-center controlled trial.2016

    • Author(s)
      Miura M, Oowada S, Hirayama Y, Hirayama A, Ito O, Kohzuki M.
    • Organizer
      10th Interantional Soceity of Physical and Rehabilitation Medicine World Congress.
    • Place of Presentation
      Kuala Lumpur Convention Centre
    • Year and Date
      2016-05-29
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K12575
  • [Presentation] 透析中の運動療法での高齢透析患者の酸化ストレス消去活性への影響2016

    • Author(s)
      三浦美佐,平山暁, 大和田滋,平山陽,伊藤修,上月正博
    • Organizer
      第 28 回腎とフリーラジカル研究会
    • Place of Presentation
      つくば国際会議場, 茨城県
    • Data Source
      KAKENHI-PROJECT-15K01702
  • [Presentation] Effects of a renal rehabilitation exercise program in patients with end-stage renal disease: study protocol for a multicenter controlled trial2016

    • Author(s)
      M. Miura, M. Kohzuki, S. Oowada, Y. Hirayama, O. Ito,A. Hirayama.
    • Organizer
      10th World Congress of the International Society of Physical and Rehabilitation Medicine
    • Place of Presentation
      Kuala Lumpur, Malaysia
    • Year and Date
      2016-05-29
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K01702
  • [Presentation] Comparison of electric bike exercise to conventional bicycle training during hemodialysis sessions on physical function in patients with end stage renal disease2016

    • Author(s)
      M Miura , R Yoshizawa, S Oowada, A Hirayama, O Ito, Y Hirayama, M Kohzuki, T Maeba
    • Organizer
      American Society of Nephrology(Kidney Week 2016)
    • Place of Presentation
      Chicago, America
    • Year and Date
      2016-11-15
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K01702
  • [Presentation] 血液透析中の運動療法または下肢電気刺激は身体機能を改善する:多施設共同治験2016

    • Author(s)
      [3]平山真喜子,吉澤亮,戀塚ゆかり,鈴木志穂,鈴木綾子, 三浦美佐,大和田滋,前波輝彦
    • Organizer
      第 6 回日本腎臓リハビリテーション学会
    • Place of Presentation
      大阪国際会議場, 大阪府
    • Year and Date
      2016-06-09
    • Data Source
      KAKENHI-PROJECT-15K01702
  • [Presentation] Effects of Aerobic Training and Electrical Stimulation to Skeletal Muscles during Hemodialysis for Patients with End-Stage Renal Disease.2015

    • Author(s)
      Miura M, Hirayama A, Oowada S, Ito O, Kohzuki M.
    • Organizer
      9th World Congress of the International Society of Physical and Rehabilitation Medicine
    • Place of Presentation
      Berlin, Germany
    • Year and Date
      2015-06-19
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K01702
  • [Presentation] 血液透析中の運動療法や下肢電気刺激は身体機能を改善する2015

    • Author(s)
      三浦美佐,平山 暁,大和田滋,伊藤 修,上月正博
    • Organizer
      第60回日本透析医学会学術集会
    • Place of Presentation
      みなとみらい,横浜市
    • Year and Date
      2015-06-26
    • Data Source
      KAKENHI-PROJECT-15K12575
  • [Presentation] 血液透析患者の酸化ストレスは抗酸化力の減弱ではなく変質による2015

    • Author(s)
      平山 暁,植田敦志,大和田滋,永瀬宗重,青柳一正
    • Organizer
      第60回日本透析医学会学術集会
    • Place of Presentation
      みなとみらい,横浜市
    • Year and Date
      2015-06-26
    • Data Source
      KAKENHI-PROJECT-15K12575
  • [Presentation] Multicenter trial of aerobic exercise in maintenance hemodialysis patients: Clinical and biochemical effects.2015

    • Author(s)
      Miura M, Hirayama A, Oowada S, Hirayama Y, Ito O, Kohzuki M.
    • Organizer
      2015 ASN
    • Place of Presentation
      San Diego, America
    • Year and Date
      2015-11-03
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K01702
  • [Presentation] Multicenter trial of aerobic exercise in maintenance hemodialysis patients : Clinical and biochemical effects.2015

    • Author(s)
      Miura M, Hirayama A, Oowada S, Ito O, Hirayama Y, Kohzuki M.
    • Organizer
      2015 Annual Meeting of the American Society of Nephrology
    • Place of Presentation
      San Diego, CA, USA
    • Year and Date
      2015-11-06
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K12575
  • [Presentation] Oxidative Stress of Chronic Kidney Disease (CKD) Patients Changes in Quality, Not in Quantity.2015

    • Author(s)
      Hirayama A, Oowada S, Ueda A, Aoyagi K.
    • Organizer
      7th Biennial Meeting of Society for Free Radical Research-Asia.
    • Place of Presentation
      Chiang-Mai, Thailand
    • Year and Date
      2015-11-30
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K12575
  • [Presentation] Effects of a renal rehabilitation exercise program in patients with CKD: Controlled trial.2015

    • Author(s)
      Miura M, Hirayama A, Oowada S, Ito O, Kohzuki M.
    • Organizer
      52th ERA-EDTA
    • Place of Presentation
      London, England
    • Year and Date
      2015-05-28
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K01702
  • [Presentation] Design of Nanoparticle therapeutics for ischemia reperfusion injuries.2014

    • Author(s)
      Nagasaki Y, Yoshitomi T, Toh K, Marushima A, Tsurushima H, Suzuki K, Matsumura A, Hirayama A, Sanada S, Yoshida A, Kitakaze M.
    • Organizer
      2nd International Meeting on Ischemia Reperfusion Injury in Transplantation.
    • Place of Presentation
      Poitiers (France)
    • Year and Date
      2014-04-25
    • Data Source
      KAKENHI-PROJECT-24591224
  • [Presentation] Preparation and evaluation of silica-containing redox nanoparticle for peritoneal dialysis which aimed at the medical treatment of chronic renal failure2013

    • Author(s)
      Matsumura T, Yaguchi T, Amraon Md, Ikeda Y, Yoshitomi T, Hirayama A, Ueda A, Nagasaki Y
    • Organizer
      Tsukuba International Conference on Materials Science
    • Place of Presentation
      Tsukuba International Congress Center, Tsukuba
    • Data Source
      KAKENHI-PROJECT-24591224
  • [Presentation] Uremic toxin indoxyl sulfate induce mitochondrial superoxide leakage.2012

    • Author(s)
      Hirayama A
    • Organizer
      19th Annual Meeting of the Society for Free Radical Biology and Medicine
    • Place of Presentation
      San Diego, CA, USA
    • Data Source
      KAKENHI-PROJECT-24591224
  • [Presentation] Application of ESR and Spin Technologies for the Control of Kidney Diseases2011

    • Author(s)
      Hirayama A, Ueda A, Nagase S, Aoyagi K, Owada S
    • Organizer
      International Workshop"Advanced ESR Studies for New Frontiers in Biofunctional Spin Science and Technology"(AEBST 2011)
    • Place of Presentation
      Kobe
    • Year and Date
      2011-11-13
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Presentation] 急性腎障害に対するナノ粒子治療の開発シンポジウムJapan Kidney Week 20112011

    • Author(s)
      平山暁,吉富徹,長崎幸夫
    • Organizer
      第55回(社)日本透析医学会学術集会・総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Presentation] Indoxyl sulfate and guanidino succinic acid directly induce mitochondrial superoxide production2011

    • Author(s)
      Hirayama A.
    • Organizer
      XLVIII ERA-EDTA Congress
    • Place of Presentation
      Prague
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Presentation] レドックス反応性ナノ粒子による腎虚血再灌流障害の治療第2011

    • Author(s)
      吉冨徹,平山暁,長崎幸夫
    • Organizer
      64回日本酸化ストレス学会学術集会
    • Place of Presentation
      北海道,ルスツ
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Presentation] Novel redox nanotherapy fof renal ischemia reperfusion injury2011

    • Author(s)
      Nagasaki Y.
    • Organizer
      XLVIII ERA-EDTA Congress
    • Place of Presentation
      Prague
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Presentation] Novel redox nanotherapy fof renal ischemia reperfusion injury2011

    • Author(s)
      Nagasaki Y, Yoshitomi T, Hirayama A
    • Organizer
      XLVIII ERA-EDTA Congress
    • Place of Presentation
      Prague, Czech Rep
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Presentation] Design of redox imaging nanoprobe using nitroxyl radical containing nanoparticle2010

    • Author(s)
      Yoshitomi T, Mamiya T, Matsui H, Hirayama A ,Nagasaki Y
    • Organizer
      SFRBM 2010-17th Annual Meeting of the Society for Free Radical Biology and Medicine
    • Place of Presentation
      Orlando, Florida
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Presentation] Novel Nanosphere Theranostic for Anti-Oxidative Stress2010

    • Author(s)
      Nagasaki Y
    • Organizer
      THE 1st INTERNATIONAL CONFERENCE FOR GREEN TECHNOLOGIES
    • Place of Presentation
      Ajou University, Suwon, Korea
    • Year and Date
      2010-02-06
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Presentation] Design of nitroxyl radicals containing nanoparticle for MR imaging of tumor2010

    • Author(s)
      Yoshitomi T, Matsumoto S, Krishna MC, Matsumoto K, Anzai K, Matsui H, Hirayama A, Nagasaki Y
    • Organizer
      The 37th Annual Meeting and Exposition of the Controlled Release Society
    • Place of Presentation
      Oregon Convention Center, Portland, Oregon, USA.
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Presentation] Development of a pH-Sensitive Reno-Protective Nano-Particle for Relief of Ischemia-Reperfusion Acute Kidney Injury2010

    • Author(s)
      Hirayama A, Yoshitomi T, Owada S, Ueda A, Matsui H, Aoyagi K, Nagasaki Y
    • Organizer
      43rd Annual meeting of the American Society of Nephrology (Renal Week 2010)
    • Place of Presentation
      Denver (abstract in J Am Soc Nephrol)
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Presentation] 反応性イメージングを目指したニトロキシルラジカル含有ナノ粒子の設計と評価2010

    • Author(s)
      吉冨徹、間宮孝、松井裕史、平山暁、長崎幸夫
    • Organizer
      第26回日本DDS学会学術集会
    • Place of Presentation
      大阪国際交流センター
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Presentation] pH応答性TEMPO含有ナノ粒子のマウス急性腎不全モデルに対する保護効果2010

    • Author(s)
      平山暁
    • Organizer
      第22回腎とフリーラジカル研究会
    • Place of Presentation
      町村会館(東京)
    • Year and Date
      2010-10-16
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Presentation] Design of pH-sensitive polymeric micelle possessing reduced forms of TEMPO for imaging of ROS2010

    • Author(s)
      Yoshitomi T, Mamiya T, Matsui H, Hirayama A, Nagasaki Y
    • Organizer
      Young Investigator's Award winning presentation
    • Place of Presentation
      Oxygen Club California World Congress, Santa Barbara, CA, USA.
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Presentation] Development of a pH-Sensitive Reno-Protective Nano-Particle for Relief of Ischemia-Reperfusion Acute Kidney Injury.2010

    • Author(s)
      Hirayama A
    • Organizer
      43rd Annual meeting of the American Society of Nenhroloev (Renal Week 2010)
    • Place of Presentation
      Colorado Convention Center (Denver, CO)
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Presentation] Healing of Oxidative Stress in Brain on the Occasion of Cerebral Ischemia-Reperfusion.2009

    • Author(s)
      Yoshitomi T, Toh K, Marushima A, Suzuki K, Tsurushima H, Hirayama A, Matsumura A, Nagasaki Y
    • Organizer
      2009 Gordon Research Conference on Biomaterials: Biocompatibility and Tissue Engineering
    • Place of Presentation
      Plymouth (USA)
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Presentation] Development of TEMPOL-Containing Nano-Particle for Continuous Superoxide Scavenging and Antihypertension2009

    • Author(s)
      Hirayama A
    • Organizer
      42nd Annual meeting of the American Society of Nephrology(Renal Week 2009)
    • Place of Presentation
      San Diego, California, United States of America
    • Year and Date
      2009-10-30
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Presentation] ラジカル含有ナノ粒子を用いた脳虚血-再潅流モデルラットにおける脳梗塞の抑制2009

    • Author(s)
      藤加珠子、吉冨徹、丸島愛樹、鈴木謙介、鶴嶋英夫、平山暁、松村明、長崎幸夫
    • Organizer
      第62回日本酸化ストレス学会学術集会
    • Place of Presentation
      福岡ポスターアワード(優秀演題賞)受賞演題)
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Presentation] 生体内ROSの可視化を目指したEPRナノプローブの創製2009

    • Author(s)
      吉冨徹、間宮孝、松井裕史、平山暁、長崎幸夫
    • Organizer
      第62回日本酸化ストレス学会学術集会
    • Place of Presentation
      福岡
    • Year and Date
      2009-06-11
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Presentation] Stable Radical-containing Nanoparticles for Anti-oxydative Stress Disease2009

    • Author(s)
      Nagasaki Y
    • Organizer
      FBPS2009
    • Place of Presentation
      Mishima
    • Year and Date
      2009-05-20
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Presentation] TEMPO含有ナノ粒子の開発と生体内動態2009

    • Author(s)
      吉冨徹、平山暁、間宮孝、松井裕史、長崎幸夫
    • Organizer
      第48回電子スピンサイエンス学会年会(SEST2009)
    • Place of Presentation
      神戸
    • Year and Date
      2009-11-12
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Presentation] Development of TEMPOL-Containing Nano-Particle for Continuous Superoxide Scavenging and Antihypertension.2009

    • Author(s)
      Hirayama A, Yoshitomi T, Ueda A, Matsui H, Owada S, Aoyagi K, Nagasaki Y
    • Organizer
      42nd Annual meeting of the American Society of Nephrology (Renal Week 2009)
    • Place of Presentation
      San Diego
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Presentation] 安定した抗酸化・降圧効果を発揮するナノ粒子化TEMPOの開発2009

    • Author(s)
      平山暁,吉冨徹,植田敦志,青柳一正,長崎幸夫
    • Organizer
      第52回日本腎臓学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2009-06-03
    • Data Source
      KAKENHI-PROJECT-21591018
  • [Presentation] In vivo EPR analysis and imaging of antihypertensive drugs on renal reducing activity.2007

    • Author(s)
      Hirayama A.
    • Organizer
      EPR 2007: A Joint Conference of 12th In Vivo EPR Spectroscopy and Imaging 9th International EPR Spin Trapping/Spin Labeling
    • Place of Presentation
      シカゴ(米国)
    • Year and Date
      2007-04-30
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590878
  • [Presentation] In vivo EPR analysis and imaging of antihypertensive drugs on renal reducing activity2007

    • Author(s)
      Hirayama A.
    • Organizer
      EPR 2007: A Joint Conference of 12th In Vivo EPR Spectroscopy and Imaging 9th International EPR Spin Trapping/ Spin Labeling
    • Place of Presentation
      Chicago, USA
    • Year and Date
      2007-04-30
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590878
  • [Presentation] Imbalance of Mitochondrial Superoxide and Intracellular Nitric Oxide in the Hyperproteinuric Phase of Puromycin Nephrosis.2007

    • Author(s)
      Hirayama A.
    • Organizer
      40th annual meeting of the American Society of Nephrology
    • Place of Presentation
      サンフランシスコ(米国)
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590878
  • [Presentation] Ketsueki Touseki no Kousanka-teki Sokumen (Antioxidataive Effects of Hemodialysis), Workshop: Oxidative Stress in Dialysis Patients, UP to DATE2007

    • Author(s)
      Hirayama A.
    • Organizer
      52nd Annual Meeting of Japanese Society for Dialysis Therapy
    • Place of Presentation
      Osaka
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590878
  • [Presentation] Imbalance of Mitochondrial Superoxide and Intracellular Nitric Oxide in the Hyperproteinuric Phase of Puromycin Nephrosis2007

    • Author(s)
      Hirayama A.
    • Organizer
      40th annual meeting of the American Society of Nephrology
    • Place of Presentation
      San Francisco, USA
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590878
  • [Presentation] 血液透析の抗酸化的側面 ワークショップ「透析患者の酸化ストレスUp to date」2007

    • Author(s)
      平山 暁
    • Organizer
      第52回日本透析医学会総会・学術集会
    • Place of Presentation
      大阪
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590878
  • [Presentation] Upper Stream Reactions of Oxidative Stress in Hemodialysis Patients.

    • Author(s)
      Hirayama A, Ueda A, Nagase S, Matsui H, Aoyagi K, Owada S.
    • Organizer
      2013 Annual meeting of the American Society of Nephrology (Kidney Week 2013)
    • Place of Presentation
      Georgia World Congress Center, Atlanta, GA, USA
    • Data Source
      KAKENHI-PROJECT-24591224
  • [Presentation] 抗炎症性と 老廃物吸着能を併せ持つシリカ含有レドック スナノ粒子の設計腹膜透析へ展開

    • Author(s)
      松村卓馬, 矢口達也,池田 豊, 吉冨 徹,植田敦志,平山 暁,長崎幸夫
    • Organizer
      つくば医 工連携フォーラム2014
    • Place of Presentation
      つくば国際会議場,つくば
    • Data Source
      KAKENHI-PROJECT-24591224
  • [Presentation] 高性能な腹膜透析液の開発を目指したシ リカ含有レドックスナノ粒子の作製と評価

    • Author(s)
      松村卓馬、矢口達也、池田 豊 、吉 冨 徹、平山 暁、植田敦志 ,植田敦志 、長崎 幸夫
    • Organizer
      第23回日本MRS年次大会
    • Place of Presentation
      横浜開港記念会館,横浜情報文化センター,波止場会館,万国橋会議センター,横浜
    • Data Source
      KAKENHI-PROJECT-24591224
  • [Presentation] Design of redox polymer-silica nanohybrid materials for effective treatment of renal failure.

    • Author(s)
      Matsumura T, Yaguchi T, Yoshitomi T, Ikeda Y, Ueda A, Hirayama A, Nagasaki Y
    • Organizer
      SPSJ International Polymer Conferences 2014
    • Place of Presentation
      EPHOCAL Tsukuba (Tsukuba, Ibaraki, Japan)
    • Year and Date
      2014-12-02 – 2014-12-04
    • Data Source
      KAKENHI-PROJECT-24591224
  • [Presentation] Novel redox polymer therapeutics for antioxidative injuries

    • Author(s)
      Nagasaki Y
    • Organizer
      17th Biennial Meeting of Society for Free Radical Research International (SFRRI 2014)
    • Place of Presentation
      Kyoto International Conference Center, Sakyo-ku, Kyoto
    • Invited
    • Data Source
      KAKENHI-PROJECT-24591224
  • [Presentation] Nanotechnology in, vivo: Redox Polymer Therapeutics

    • Author(s)
      Nagasaki Y
    • Organizer
      40th Annual Meeting & Exposition of the Controlled Release Society
    • Place of Presentation
      Hawaii Convention Center, Honolulu, Hawaii, U.S.A
    • Invited
    • Data Source
      KAKENHI-PROJECT-24591224
  • [Presentation] Nano-kidney possessing oxidative stress suppression character.

    • Author(s)
      Nagasaki Y, Yaguchi T, Matsumura T, Yoshitomi T, Ikeda Y, Ueda A, Hirayama A.
    • Organizer
      ASN Kidney Week 2014, 2014 Annual Meeting of the American Society of Nephrology.
    • Place of Presentation
      Philadelphia, PA (USA)
    • Year and Date
      2014-11-13 – 2014-11-16
    • Data Source
      KAKENHI-PROJECT-24591224
  • 1.  NAGASAKI Yukio (90198309)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 32 results
  • 2.  NAGASE Sohji (10189128)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
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    # of Collaborated Products: 20 results
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    # of Collaborated Products: 18 results
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    # of Collaborated Products: 1 results
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    # of Collaborated Products: 14 results
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    # of Collaborated Products: 2 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 12.  YOSHITOMI Toru (20585799)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 10 results
  • 13.  MORITAKE Takashi (50450432)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  MATSUMOTO Yoshitaka (70510395)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  KOYAMA Akio (80111384)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  YANAKA Kiyoyuki (10312307)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  YOH Keigyou (90323302)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  松野 邦晴 (50420708)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 19.  坪井 康次 (90188615)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  伊藤 修 (00361072)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 10 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  鶴嶋 英夫 (50315470)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 23.  滝川 知司 (60450227)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 24.  松崎 秀夫 (00334970)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  石川 博 (30089784)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  赤池 敏宏 (30101207)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  松丸 祐司 (70323300)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  池田 豊 (70425734)
    # of Collaborated Projects: 1 results
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  • 30.  井川 正道 (60444212)
    # of Collaborated Projects: 1 results
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  • 31.  岡沢 秀彦 (50360813)
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    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 1 results
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  • 33.  OOWADA Shigeru
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 10 results
  • 34.  INOUE Yoshiaki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 35.  SHIMOJO Nobutake
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    # of Collaborated Products: 1 results
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  • 37.  NAKAMURA Maki
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    # of Collaborated Products: 1 results
  • 38.  河野 了
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  • 39.  小山 泰明
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  • 40.  榎本 有希
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