Yamamoto Hirofumi 山本浩文

… Alternative Names

YAMAMOTO Hirofumi 山本浩文

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Researcher Number	30322184
Other IDs
External Links
Affiliation (Current)	2025: 大阪大学, 大学院医学系研究科, 教授
Affiliation (based on the past Project Information) *help	2025: 大阪大学, 大学院医学系研究科, 教授 2022 – 2024: 大阪大学, 大学院医学系研究科, 教授 2015 – 2022: 大阪大学, 医学系研究科, 教授 2015: 大阪大学, 医学(系)研究科(研究院), 教授 2015: 大阪大学, 大学院医学系研究科, 教授 … More 2012 – 2014: 大阪大学, 医学(系)研究科(研究院), 准教授 2013: 大阪大学, 附属病院消化器外, 准教授 2009 – 2012: Osaka University, 医学系研究科, 講師 2011: 大阪大学, 医学(系)研究科(研究院), 講師 2011: 大阪大学, 医学系・研究科, 講師 2007 – 2008: 大阪大学, 医学系研究科, 助教 2000 – 2006: 大阪大学, 医学系研究科, 助手 2002: 大阪大学, 医学研究科, 助手 Less
Review Section/Research Field	Principal Investigator Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Digestive surgery / General surgery / Biological Sciences / General surgery / Digestive surgery Except Principal Investigator Basic Section 55020:Digestive surgery-related / Digestive surgery / General surgery / Basic Section 53010:Gastroenterology-related … More / Basic Section 50020:Tumor diagnostics and therapeutics-related / Digestive surgery / Basic Section 42020:Veterinary medical science-related / Basic Section 56010:Neurosurgery-related / Basic Section 90130:Medical systems-related / Basic Section 56040:Obstetrics and gynecology-related / Basic Section 62010:Life, health and medical informatics-related / Basic Section 52040:Radiological sciences-related / Experimental pathology / Tumor diagnostics / General surgery / Biological Sciences Less
Keywords	Principal Investigator DDS / 大腸癌 / 消化器癌 / microRNA / マイクロRNA / colorectal cancer / 癌幹細胞 / ICG / 核酸医療 / ドラッグデリバリーシステム … More / 全身デリバリー / 核酸 / dominant negative TCF / TCF decoy / antisense cyclin D1 / ATAC-PCR / 核酸医薬 / 転移 / 微小環境 / 食道癌 / 肝癌 / アデノウイルス / cyclin D1 / 微小転移 / 多分子制御 / 静止期癌幹細胞 / 治療抵抗性 / シングルセル解析 / 細胞老化 / 効果増強 / 高分子薬剤 / 腫瘍間質 / 癌間質 / ナノ粒子 / 高分子製剤 / sCA / インテグリン / インテグリンB1 / 高分子医薬 / 癌微小環境 / 炎症性疾患 / 低侵襲治療 / 難治性癌 / 腫瘍集積性 / 肝臓集積性 / 動物モデル / 膵癌 / 抗癌剤 / 癌治療 / バイオテクノロジー / 光治療 / KRAS変異 / 核酸治療 / 治療薬探索 / miR-29 / スーパーアパタイト / 樹状細胞 / 炎症性腸疾患 / liver metastasis / Wnt signal / 肝転移 / lymph node metastasis / gene expression profile / esophageal cancer / hepatocellular carcinoma / 転移予測 / リンパ節転移 / 網羅的遺伝子解析 / Key word / 遺伝子発現 / 網羅解析 / エピゲノム / リプログラミング / CPC-Apcマウス / リプログラム / APC遺伝子 / P53 / MAF / CPC/Apc mouse / miR-302 / miR-369 / miR-200c / AP-１ / MAPK/ERK / セツキシマブ / K-ras遺伝子変異 / AKT / nanoparticle / carbonate apatite / PI3K/Akt pathway / RAF/MEK/ERK pathway / KRAS / 骨髄のmicroRNA / 癌・間質転換 / 大腸癌のmicroRNA / ナノデリバリー / 腫瘍血管分化 / 骨髄DTC / ナノデリバリーシステム / 低酸素 / disease recurrence / invasion / C4.4A / micrometastasis / hypoxia / ナノテクノロジー / 炭酸アパタイト / 浸潤 / 癌 / Cre-LoxP / Antisense / CDC25 phosphatase / アンチャンス / アデノウィルス / アンチセンス / 遺伝子治療 / 予後 / 癌疫学 / COX-2 / CDC25 / 悪性度診断 / 分子診断 … More Except Principal Investigator 大腸癌 / 癌幹細胞 / 遺伝子発現プロファイル / DNAチップ / 大腸がん / 肝転移 / 三次元ゲノム構造 / DDS / DNA chip / 遺伝子発現 / gene expression profile / 臨床応用 / 核酸治療 / シングルセル解析 / KLF5 / 遠隔診断 / クロマチンパターン / 細胞診断 / ホモロジー / CTC / 初代培養 / Sdc4 / 腹膜播種 / PD-L1 / 免疫チェックポイント阻害剤 / EMT / 小胞体ストレス / 肝細胞癌 / オリゴヌクレオチド / 消化器癌 / リンパ節転移 / liver metastasis / colorectal cancer / cDNA microarray / 網羅的遺伝子解析 / ドラッグデリバリーシステム / 幹細胞 / 血管新生 / MSH2 / microRNA / UHRF1 / 胆道癌 / 治療抵抗性 / G0期 / Persister / 転移性癌 / 肝障害 / Sox2 / SOX2 / 癌精巣抗原 / SEMA3E / PLXND1 / 培養法 / 核酸療法 / 扁平上皮癌 / 犬 / リンチ症候群 / 上皮間葉転換 / 内在性レトロウイルス配列 / ARC遺伝子 / 上皮間葉移行 / 脳腫瘍 / 特異抗体 / 放射線 / 癌幹細胞性 / Lrig1 / 代謝機構 / 代謝 / 臨床サンプル / 癌代謝 / LncRNA01534 / 小胞体ストレス反応 / プロテアソーム / ERストレス / LINC01534 / lnc RNA / 抗体治療 / 中皮腫 / 核酸医薬 / 悪性中皮腫 / sCA / IFN alpha / インターフェロンアルファ / CpG / データの構造化 / ホモロジープロファイル法 / ビッグデータ / クロマチン解析 / ホモロジー法 / ヒト検体 / 動物モデル / 癌微小環境 / 間葉系幹細胞 / 浮遊中皮細胞 / 中皮細胞 / 浮遊播種病変 / 卵巣癌 / 転移性大腸癌 / 乳癌 / MUC1 / ｐ５３ / ノックアウトマウス / p53 / MAF / クロマチン / 画像診断 / PDXモデル / 血液中の癌細胞 / 遺伝子変異 / 培養 / Sdc４ / モノクロ―ナル抗体 / EPR効果 / スーパーナノアパタイト / 核酸医薬品 / 胃癌腹膜播種 / Western blotting / WST1 / super cabonate apatite / drug deliverly / Bcl2 / 胃癌 / 粒子線 / 光子線 / がん細胞 / 医学物理学 / 医学物理 / 浸潤能 / 転移 / cdc42 / Rac1 / がん転移 / 転移能 / 細胞浸潤能 / 陽子線 / 炭素イオン線 / γ線 / ドラッグデリバリー / 免疫チェックポイント / 磁気温熱療法 / 免疫チェックポイント阻害 / 温熱療法 / 癌 / がん / FGF / FGFR / 浸潤転移 / インテグリン / 機能性RNA / オートファジー / LncRNA / Long non-coding RNA / endoscopic biopsy / molecular diagnostic system / 遣伝子診断システム / 生検標本 / 遺伝子診断システム / Gene Expression Profiling / angiogenesis / IFN-receptor / chemotherapy / IFN-α / portal venous thrombus / advanced cancer / hepatocellular carcinoma / 難治性進行癌 / Angiopoietin / Fas-L / Fas / NK細胞 / TRAIL / IFN併用化学療法 / IFN受容体 / 化学療法 / インターフェロン / 門脈内腫瘍栓 / 進行癌 / robotically assisted surgery / autonomous robot / laparoscopic surgery / ロボット手術 / 腹腔鏡 / autonomous robotic surgery / 手術支援ロボット / 腹腔鏡下手術 / multi-center system / clinical application / lymph node metastasis / Colorectal cancer / 臨床診断型DNAチップ / 予後予測システム / 大腸菌 / マルチセンターシステム / Translational research / Digestive organ cancer / 予後予測診断 / 肝転移予測 / ヒト全遺伝子型DNAチップ / 遺伝子発現プロフィル / トランスレーショナルリサーチ / superficial colon cancer / cell cycle regulator molecules / Lymph node metastasis / superficial esophageal cancer / HSP70 / apoptosis / 大腸sm癌 / Cyclin D1 / heat shock protein / 細胞周期関連分子 / 食道表在癌 / Prediction of metastasis / 個性化診断 / マイクロアレイ / 転移予測 / cDNAマイクロアレイ / 感受性診断 / 感受性性診断 / 次世代シーケンサー / 非侵襲性KRAS変異検査 / グルコース内包スーパーアパタイト超微細ナノ粒子 / 新規癌治療法 / 胞内ROS活性 / 消化器癌に対する新規治療法 / スーパーアパタイト超微細ナノ粒子法 / 新規ドラッグデリバリーシステム / ROS活性 / 抗腫瘍効果 / 新規治療法 / 難治性消化器癌 / 高濃度グルコースを内包した超微細ナノ粒子 / スーパーアパタイト / 超微細ナノ粒子 / 術中迅速診断 / 術中迅速検査 / 側方郭清 / OSNA法 / 直腸癌 / 薬剤感受性 / 癌の多様性 / 予後診断用臨床チップ / 個別化医療 / 予後予測 / パスウェイ / 予測診断 / 予後・治療応答性 / バイオマーカー / メタボロミクス / プロテオミクス / ファンクショナルゲノミクス / 大規模症例登録 / OMICS / 個別医療 / 免疫組織染色 / DNAマイクロアレイ / 異倍体 / 細胞融合 / PDGFR / ANG2 / 内皮細胞 / 皮下腫瘍 / 血管内皮細胞 / 周皮細胞 / VEGF / Angiopoietin-2 / Wnt系シグナル / 細胞増殖 / βカテニン / HVJ envelope / decoy / 転写因子 / 癌遺伝子治療 / β-catenin / Wnt signal / TCF decoy / ラット肝癌モデル / CDAA / JTE-522 / 食道癌 / 胆管癌 / 膵癌 / 肝癌 / COX-2 Less

Characterization of G0 persisters in colon cancer
- Principal Investigator
  
  原口直紹
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  The University of Osaka
胆道癌におけるUHRF1による腫瘍制御機構の解明とmicroRNAによる新規治療法の開発
- Principal Investigator
  
  武藤亮
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Fukushima Medical University
MSH2プロモーターの異常活性化が三次元ゲノム構造を介して大腸癌の悪性化に与える影響
- Principal Investigator
  
  横山雄起
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  The University of Osaka
犬口腔扁平上皮癌の根治を目指した全身投与可能な核酸療法の確立
- Principal Investigator
  
  野口俊助
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Osaka University
消化器癌CTCの長期培養による癌幹細胞株の樹立
- Principal Investigator
  
  平木将之
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Osaka University
大腸癌の転移を誘導するEMT関連癌幹細胞分画と転移性ニッチの解明
- Principal Investigator
  
  福島菖子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Osaka University
多分子標的型核酸と高性能化DDSによって転移性癌をリセットするムーンショット計画Principal Investigator
- Principal Investigator
  
  山本浩文
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  The University of Osaka
正常細胞に影響を与えない癌幹細胞特異抗体の取得
- Principal Investigator
  
  幸田志穂里
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Osaka University
PDX同所移植モデルを用いた脳腫瘍に対する新規核酸治療剤の開発
- Principal Investigator
  
  井上彬
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Osaka University
シングルセル解析が紐解く老化細胞と癌幹細胞の治療抵抗性メカニズムPrincipal Investigator
- Principal Investigator
  
  山本浩文
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Osaka University
正常組織に影響を与えない癌幹細胞標的分子の探索
- Principal Investigator
  
  奥崎大介
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Osaka University
未分化マーカーを指標とした新規癌幹細胞マーカーの取得
- Principal Investigator
  
  吉村大士
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Osaka University
腫瘍特異的に集積するDDSを用いた転移性癌の核酸治療
- Principal Investigator
  
  室谷昌俊
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Osaka University
内在性ウイルス粒子を介した細胞間コミュニケーションとその癌進展への関わり
- Principal Investigator
  
  西田尚弘
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Osaka University
KLF5を基軸とした新たな癌関連分子制御メカニズムの解明
- Principal Investigator
  
  三代雅明
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Sapporo Medical University
  Osaka University
リンチ症候群関連大腸癌の病態に寄与する三次元ゲノム構造の解明
- Principal Investigator
  
  横山雄起
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Osaka University
シングルセル解析を駆使した癌幹細胞の捕捉と新規治療法の開発
- Principal Investigator
  
  Shamma A.A.Awad
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Osaka University
A strategy for improving tumor microenvironment that contributes to the efficacy of macromolecular drugs.Principal Investigator
- Principal Investigator
  
  Yamamoto Hirofumi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Osaka University
Development of lung cytodiagnosis support system using homology profile method
- Principal Investigator
  
  Nakane Kazuaki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90130:Medical systems-related
- Research Institution
  Osaka University
Therapy against HCC by potential ability of CpG endowed by DDS
- Principal Investigator
  
  Tsujimura Naoto
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Osaka University
Elucidation of significance of Sdc4 in malignant mesothelioma and development of novel therapy
- Principal Investigator
  
  Shibata Satoshi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Osaka University
Role of LINC01534 in colorectal cancer
- Principal Investigator
  
  Ichihara Momoko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Sapporo Medical University
  Osaka University
Elucidation of metabolic machinery of cancer stem cell by investigating clinical samples with single cell analysis.
- Principal Investigator
  
  Itakura Hiroaki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Osaka University
Mechanism of cancer stem cell maintenance by Lrig1 using transgenic mice
- Principal Investigator
  
  Makino Shunichiro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Osaka University
Elucidation of the role of the MAF gene in the occurrence and progression of colorectal cancer
- Principal Investigator
  
  Okuzaki Daisuke
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Osaka University
Development of immune checkpoint therapy for metastatic colorectal cancer by targeting MUC1-C
- Principal Investigator
  
  Hiraki Masayuki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Osaka University
Identification of KLF5 related three-dimensional genome structure
- Principal Investigator
  
  Otsuka Masahisa
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Osaka University
Investigation of cancer stem-like properties of ovarian cancer cells associated with the floating mesothelium
- Principal Investigator
  
  Shishido Akemi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Osaka University
Diagnosis and therapy for cancer stem cells by targeting membranous Sdc4
- Principal Investigator
  
  Wu Xin
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Osaka University
Identification of cancer stem cells in blood samples of colorectal cancer patients
- Principal Investigator
  
  Inoue Akira
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Osaka University
Database of effect of different radiation on cancer metastatic potential
- Principal Investigator
  
  Koizumi Masahiko
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Osaka University
Development of a peritoneal dissemination treatment for gastric cancer by miRNA using super carbonate nanoapatite
- Principal Investigator
  
  Sakamoto Nobuhiro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Nagoya City University
Development of innovative nucleic acid medicine using EPR enhancer iNaDPrincipal Investigator
- Principal Investigator
  
  Yamamoto Hirofumi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Osaka University
Cytological image analysis via the concept of the homology
- Principal Investigator
  
  Nakane Kazuaki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 62010:Life, health and medical informatics-related
- Research Institution
  Osaka University
Development of therapy for the cancer stem cell by LncRNA
- Principal Investigator
  
  Otsuka Masahisa
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor diagnostics
- Research Institution
  Osaka University
The cross-signaling of FGF receptor and integrin in cancer invasion and metastasis.
- Principal Investigator
  
  Mori Seiji
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Morinomiya University of Medical Sciences
Augmentation of anti-tumor effect by less invasive hyperthermia
- Principal Investigator
  
  Takeda Tsutomu
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Osaka University
Systemic delivery of microRNA for therapy of IBDPrincipal Investigator
- Principal Investigator
  
  Yamamoto Hiofumi
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General surgery
- Research Institution
  Osaka University
Development of nucleic acid therapy using rapid acting DDSPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Hirofumi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Osaka University
A novel noninvasive screening assay for RAS mutations in the peripheral blood sample using next-generation sequencing for anti-EGFR antibodies therapy
- Principal Investigator
  
  Takemasa Ichiro
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Sapporo Medical University
  Osaka University
Role of epigenetic modification by cancer reprograming in colon tumorigenesis modelPrincipal Investigator
- Principal Investigator
  
  Yamamoto Hirofumi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Osaka University
Prediction of lateral lymph node metastasis by inspection of the para-rectal lymph nodes using the one-step nucleic acid amplification (OSNA) assay in the lower rectal cancer
- Principal Investigator
  
  Hata Taishi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Osaka University
Development of systemic therapy using nanoparticles incorporating glucose against gastrointestinal cancer.
- Principal Investigator
  
  INOUE Akira
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Osaka University
macro-cosmos in interaction between cancer and host microenvironments.Principal Investigator
- Principal Investigator
  
  YAMAMOTO Hirofumi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Osaka University
Identification of microRNA that correctly inhibits KRAS-related downstream signal transduction in KRAS mutant colorectal cancerPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Hirofumi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Osaka University
Clinical application of gene expression signature as a predictor of recurrence in colorectal cancer
- Principal Investigator
  
  TAKEMASA Ichiro
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Osaka University
Integrated research for respective role of cancer and microenvironment towards clinical applicationPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Hirofumi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Osaka University
炭酸アパタイトナノテクノロジーによる難治性固形癌の治療法の開発Principal Investigator
- Principal Investigator
  
  山本浩文
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General surgery
- Research Institution
  Osaka University
Clinical application of OMICS for isolation of novel marker in colorectal cancer
- Principal Investigator
  
  TAKEMASA Ichiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Osaka University
DNAマイクロアレイによる幹細胞融合による消化器発癌の可能性の検討
- Principal Investigator
  
  門田守人
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General surgery
- Research Institution
  Osaka University
The development of novel treatment through the hepatocellular carcinoma (HCC) specific siginaling pathway and molecular based gene expression profiling for advanced HCC
- Principal Investigator
  
  UMESHITA Koji
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Osaka University
Molecular Diagnosis of colorectal cancer using preoperative endoscopic biopsies with clinical DNA chip
- Principal Investigator
  
  TAKEMASA Ichiro
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Osaka University
血管周皮細胞を標的とした転移性肝癌に対する新規治療法の開発
- Principal Investigator
  
  MONDEN Morito
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General surgery
- Research Institution
  Osaka University
Development of Autonomous-robotic surgery using image data of the operative field in the lapaproscopic surgery
- Principal Investigator
  
  SEKIMOTO Mitsugu
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Osaka University
Development of novel therapeutic strategy based on malignant nature of colorectal cancerPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Hirofumi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Osaka University
Translational research in the establishment of treatment strategy for gastrointestinal cancers
- Principal Investigator
  
  MONDEN Morito
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General surgery
- Research Institution
  Osaka University
Clinical application of molecular prediction system with DNA chip technology for colorectal cancer
- Principal Investigator
  
  IKEDA Masataka, 大植雅之
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Osaka University
CDC25phosphataseを標的とした消化器癌の治療Principal Investigator
- Principal Investigator
  
  山本浩文
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
転写因子遺伝子に対するdecoyを利用した癌遺伝子治療の基礎的研究 -HVJ envolope法によるTCF docoyを用いた癌の遺伝子治療-
- Principal Investigator
  
  中森正二
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General surgery
- Research Institution
  Osaka University
Clinicalapplication of gene expression profiles of GI and hepatic cancers determined by ATAC-PCR.Principal Investigator
- Principal Investigator
  
  YAMAMOTO Hirohumi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Osaka University
Analysis of colon cancer related genes by cDNA microarray
- Principal Investigator
  
  SEKIMOTO Mitsugu
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Osaka University
Decision making of treatment of superficial esophageal and colon cancers according to their biological character.
- Principal Investigator
  
  YANO Masahiko, 田村茂行
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Osaka University
COX-2を分子標的とした難治性消化器癌の化学予防・治療に関する研究
- Principal Investigator
  
  塩崎均
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
消化器癌の進展・予後に関する総括的臨床研究Principal Investigator
- Principal Investigator
  
  山本浩文
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Cyclin D1を分子標的とした治療不能消化器癌に対する遺伝子治療研究Principal Investigator
- Principal Investigator
  
  山本浩文
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Digestive surgery
- Research Institution
  Osaka University

[Book] 『癌転移のメカニズムがよくわかる肺転移のすべて』2.網羅的遺伝子・タンパク解析 1)DNAマイクロアレイ2005
- Author(s)
  竹政伊知朗, 池田正孝, 山本浩文, 関本貢嗣, 門田守人
- Total Pages
  146
- Publisher
  永井書店
- Data Source
  KAKENHI-PROJECT-15209040
[Book] 『癌転移のメカニズムがよくわかる肺転移のすべて』2.網羅的遺伝子・タンパク解析 1)DNAマイクロアレイ2005
- Author(s)
  竹政伊知朗, 池田正孝, 山本浩文, 関本貢嗣, 門田守人
- Total Pages
  146
- Publisher
  永井書店
- Data Source
  KAKENHI-PROJECT-17591396
[Journal Article] Toxoplasma IWS1 Determines Fitness in Interferon-γ-Activated Host Cells and Mice by Indirectly Regulating ROP18 mRNA Expression.2023
- Author(s)
  Hashizaki Emi、Sasai Miwa、Okuzaki Daisuke、Nishi Tsubasa、Kobayashi Takashi、Iwanaga Shiroh、Yamamoto Masahiro
- Journal Title
  
  mBio
  
  Volume: 14 Issue: 1
- DOI
  10.1128/mbio.03256-22
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07984, KAKENHI-PROJECT-22K19434, KAKENHI-PROJECT-21KK0137, KAKENHI-PROJECT-20H03477, KAKENHI-PROJECT-17H04649, KAKENHI-PLANNED-20H05771, KAKENHI-PROJECT-19H00970, KAKENHI-PROJECT-18H02642, KAKENHI-PROJECT-21K06986, KAKENHI-PROJECT-23K27671
[Journal Article] A genetic method specifically delineates Th1-type Treg cells and their roles in tumor immunity2023
- Author(s)
  Okamoto Masaaki、Sasai Miwa、Kuratani Ayumi、Okuzaki Daisuke、Arai Masaya、Wing James B.、Sakaguchi Shimon、Yamamoto Masahiro
- Journal Title
  
  Cell Reports
  
  Volume: 42 Issue: 7 Pages: 112813-112813
- DOI
  10.1016/j.celrep.2023.112813
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-20H05770, KAKENHI-PLANNED-20H05771, KAKENHI-PROJECT-19H00970, KAKENHI-PROJECT-23K27671
[Journal Article] Correction: Multiple knockout mouse and embryonic stem cell models reveal the role of miR-124a in neuronal maturation2023
- Author(s)
  Chaya T, Maeda Y, Sugimura R, Okuzaki D, Watanabe S, Varner LR, Motooka D, Gyoten D, Yamamoto H, Kato H, Furukawa T.
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 299 Issue: 3 Pages: 103066-103066
- DOI
  10.1016/j.jbc.2023.103066
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K27671
[Journal Article] Tumor-suppressive role of the musculoaponeurotic fibrosarcoma gene in colorectal cancer2023
- Author(s)
  Itakura Hiroaki、Hata Tsuyoshi、Okuzaki Daisuke、Takeda Koki、Iso Kenji、Qian Yamin、Morimoto Yoshihiro、Adachi Tomohiro、Hirose Haruka、Yokoyama Yuhki、Ogino Takayuki、Miyoshi Norikatsu、Takahashi Hidekazu、Uemura Mamoru、Mizushima Tsunekazu、Hinoi Takao、Mori Masaki、Doki Yuichiro、Eguchi Hidetoshi、Yamamoto Hirofumi
- Journal Title
  
  iScience
  
  Volume: 26 Issue: 4 Pages: 106478-106478
- DOI
  10.1016/j.isci.2023.106478
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08356, KAKENHI-PROJECT-23K08128, KAKENHI-PROJECT-23K27671
[Journal Article] A quantitative evaluation method utilizing the homology concept to assess the state of chromatin within the nucleus of lung cancer2023
- Author(s)
  Yokoyama Yuhki、Kanayama Kazuki、Iida Kento、Onishi Masako、Nagatomo Tadasuke、Ito Mayu、Nagumo Sachiko、Kawahara Kunimitsu、Morii Eiichi、Nakane Kazuaki、Yamamoto Hirofumi
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1
- DOI
  10.1038/s41598-023-46213-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03839
[Journal Article] Chk1 suppression leads to a reduction in the enhanced radiation-induced invasive capability on breast cancer cells2021
- Author(s)
  Adachi Takanori、Zhao Wantong、Minami Kazumasa、Yokoyama Yuhki、Okuzaki Daisuke、Kondo Rika、Takahashi Yutaka、Tamari Keisuke、Seo Yuji、Isohashi Fumiaki、Yamamoto Hirofumi、Koizumi Masahiko、Ogawa Kazuhiko
- Journal Title
  
  Journal of Radiation Research
  
  Volume: 62 Issue: 5 Pages: 764-772
- DOI
  10.1093/jrr/rrab049
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07632
[Journal Article] Improved In Vivo Delivery of Small RNA Based on the Calcium Phosphate Method2021
- Author(s)
  Wu Xin、Yokoyama Yuhki、Takahashi Hidekazu、Kouda Shihori、Yamamoto Hiroyuki、Wang Jiaqi、Morimoto Yoshihiro、Minami Kazumasa、Hata Tsuyoshi、Shamma Awad、Inoue Akira、Ohtsuka Masahisa、Shibata Satoshi、Kobayashi Shogo、Akai Shuji、Yamamoto Hirofumi
- Journal Title
  
  Journal of Personalized Medicine
  
  Volume: 11 Issue: 11 Pages: 1160-1160
- DOI
  10.3390/jpm11111160
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07632, KAKENHI-PROJECT-21H04831
[Journal Article] Syntenin-1 promotes colorectal cancer stem cell expansion and chemoresistance by regulating prostaglandin E2 receptor2020
- Author(s)
  Iwamoto Kazuya、Takahashi Hidekazu、Okuzaki Daisuke、Osawa Hideo、Ogino Takayuki、Miyoshi Norikatsu、Uemura Mamoru、Matsuda Chu、Yamamoto Hirofumi、Mizushima Tsunekazu、Mori Masaki、Doki Yuichiro、Eguchi Hidetoshi
- Journal Title
  
  British Journal of Cancer
  
  Volume: 123 Issue: 6 Pages: 955-964
- DOI
  10.1038/s41416-020-0965-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08356, KAKENHI-PROJECT-20K09056, KAKENHI-PROJECT-18K08678
[Journal Article] miR-4711-5p regulates cancer stemness and cell cycle progression via KLF5, MDM2 and TFDP1 in colon cancer cells2020
- Author(s)
  Morimoto Y, Mizushima T, Wu X, Okuzaki D, Yokoyama Y, Inoue A, Hata T, Hirose H, Qian Y, Wang J, Miyoshi N, Takahashi H, Haraguchi N, Matsuda C, Doki Y, Mori M, Yamamoto H.
- Journal Title
  
  Br J Cancer
  
  Volume: 122 Issue: 7 Pages: 1037-1049
- DOI
  10.1038/s41416-020-0758-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H04059
[Journal Article] DCLK1 integrates induction of TRIB3, EMT, drug resistance and poor prognosis in colorectal cancer2020
- Author(s)
  Makino Shunichiro、Takahashi Hidekazu、Okuzaki Daisuke、Miyoshi Norikatsu、Haraguchi Naotsugu、Hata Taishi、Matsuda Chu、Yamamoto Hirofumi、Mizushima Tsunekazu、Mori Masaki、Doki Yuichiro
- Journal Title
  
  Carcinogenesis
  
  Volume: 41 Issue: 3 Pages: 394-396
- DOI
  10.1093/carcin/bgaa016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08356
[Journal Article] Combination of Immunotherapy and Hyperthermia2019
- Author(s)
  Kubota Y, Takeda T, Takeda T, Noda T, Hattori N, Nakamura K, Yasuda T, Hasegawa T, Yokoyama Y, Yamamoto H, Takeda H.
- Journal Title
  
  Gan To Kagaku Ryoho
  
  Volume: 46 Pages: 1605-1607
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10548
[Journal Article] A miR-29b Byproduct Sequence Exhibits Potent Tumor-Suppressive Activities via Inhibition of NF-κB Signaling inKRAS-Mutant Colon Cancer Cells2018
- Author(s)
  Inoue Akira、Mizushima Tsunekazu、Wu Xin、Okuzaki Daisuke、Kambara Nanami、Ishikawa Sho、Wang Jiaqi、Qian Yamin、Hirose Haruka、Yokoyama Yuhki、Ikeshima Ryo、Hiraki Masayuki、Miyoshi Norikatsu、Takahashi Hidekazu、Haraguchi Naotsugu、Hata Taishi、Matsuda Chu、Doki Yuichiro、Mori Masaki、Yamamoto Hirofumi
- Journal Title
  
  Molecular Cancer Therapeutics
  
  Volume: in press Issue: 5 Pages: 977-987
- DOI
  10.1158/1535-7163.mct-17-0850
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04920, KAKENHI-PROJECT-18H04059
[Journal Article] Enhancing Antitumor Effects Using Hyperthermia (Including Immune Checkpoint Inhibitor)2018
- Author(s)
  Takeda T, Kubota Y, Takeda T, Nakano Y, Nogami Y, Honjoh I, Takeda H, Yokoyama Y, Yamamoto H.
- Journal Title
  
  Gan To Kagaku Ryoho
  
  Volume: 45 Pages: 1479-1481
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10548
[Journal Article] Effects of Immune Checkpoint Inhibitor Combined with Dendritic Cell Therapy and Hyperthermia2018
- Author(s)
  Takeda T, Kubota Y, Takeda T, Tanaka C, Morita S, Hattori N, Takeda H, Yokoyama Y, Yamamoto H.
- Journal Title
  
  Gan To Kagaku Ryoho
  
  Volume: 45 Pages: 1472-1474
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10548
[Journal Article] Mesothelial cells facilitate cancer stem-like properties in spheroids of ovarian cancer cells.2018
- Author(s)
  Shishido A, Mori S, Yokoyama Y, Hamada Y, Minami K, Qian Y, Wang J, Hirose H, Wu X, Kawaguchi N, Nagumo S, Matsuura N, Yamamoto H.
- Journal Title
  
  Oncol Rep
  
  Volume: 4 Pages: 2105-2114
- DOI
  10.3892/or.2018.6605
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08775, KAKENHI-PROJECT-18K15318
[Journal Article] Overexpression of collagen type III in injured myocardium prevents cardiac systolic dysfunction by changing the balance of collagen distribution.2018
- Author(s)
  Uchinaka A, Yoshida M, Tanaka K, Hamada Y, Mori S, Maeno Y, Miyagawa S, Sawa Y, Nagata K, Yamamoto H, Kawaguchi N.
- Journal Title
  
  J Thorac Cardiovasc Sug.
  
  Volume: 156 Issue: 1 Pages: 217-226
- DOI
  10.1016/j.jtcvs.2018.01.097
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08775
[Journal Article] Photodynamic Therapy Using Indocyanine Green Loaded on Super Carbonate Apatite as Minimally Invasive Cancer Treatment2018
- Author(s)
  Tamai Koki、Mizushima Tsunekazu、Wu Xin、Inoue Akira、Ota Minori、Yokoyama Yuhki、Miyoshi Norikatsu、Haraguchi Naotsugu、Takahashi Hidekazu、Nishimura Junichi、Hata Taishi、Matsuda Chu、Doki Yuichiro、Mori Masaki、Yamamoto Hirofumi
- Journal Title
  
  Molecular Cancer Therapeutics
  
  Volume: in press Issue: 7 Pages: 1613-1622
- DOI
  10.1158/1535-7163.mct-17-0788
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04920, KAKENHI-PROJECT-18H04059
[Journal Article] The Supercarbonate Apatite-MicroRNA Complex Inhibits Dextran Sodium Sulfate-Induced Colitis2018
- Author(s)
  Fukata T、Mizushima T、Nishimura J、Okuzaki D、Wu X、Hirose H、Yokoyama Y、Kubota Y、Nagata K、Tsujimura N、Inoue A、Miyoshi N、Haraguchi N、Takahashi H、Hata T、Matsuda C、Kayama H、Takeda K、Doki Y、Mori M、Yamamoto H
- Journal Title
  
  Molecular Therapy - Nucleic Acids
  
  Volume: 12 Pages: 658-671
- DOI
  10.1016/j.omtn.2018.07.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H04059
[Journal Article] Evaluation of dermal wound healing activity of synthetic peptide SVVYGLR2017
- Author(s)
  Uchinaka Ayako、Kawaguchi Naomasa、Ban Tsuyoshi、Hamada Yoshinosuke、Mori Seiji、Maeno Yoshitaka、Sawa Yoshiki、Nagata Kohzo、Yamamoto Hirofumi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 491 Issue: 3 Pages: 714-720
- DOI
  10.1016/j.bbrc.2017.07.124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08775
[Journal Article] The CD44 standard isoform contributes to radioresistance of pancreatic cancer cells2017
- Author(s)
  Tsubouchi Kento、Minami Kazumasa、Hayashi Naoki、Yokoyama Yuhki、Mori Seiji、Yamamoto Hirofumi、Koizumi Masahiko
- Journal Title
  
  Journal of Radiation Research
  
  Volume: 58 Issue: 6 Pages: 816-826
- DOI
  10.1093/jrr/rrx033
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08775
[Journal Article] X-ray and Carbon Ion Beam Irradiation Inhibited Angiogenesis via Integrin Up-regulation2017
- Author(s)
  Minami K, Hamada Y, Kawaguchi N, Mori S, Yokoyama Y, Oki Y, Adachi T, Kondo R, Shishido A, Matsushita Y, Usuki T, Manabe M, Koizumi M, Ogawa K, and Yamamoto H
- Journal Title
  
  Nano Biomed
  
  Volume: 9 Pages: 94-104
- NAID
  130006415696
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08775
[Journal Article] The changes in metastatic potential of radioresistant cancer cell line generated by frequent X-ray.2017
- Author(s)
  Minami K, Hamada Y, Kawaguchi N, Mori S, Manabe M, Nakatani K, Tsubouchi K, Hayashi N, Yamamoto H, Koizumi M,
- Journal Title
  
  OHEM
  
  Volume: E001 Pages: 1-12
- Data Source
  KAKENHI-PROJECT-17K08775
[Journal Article] Innovative Delivery of siRNA to Solid Tumors by Super Carbonate Apatite.2015
- Author(s)
  Wu X, Yamamoto H, Nakanishi H, Yamamoto Y, Inoue A, Tei M, Hirose H, Uemura M, Nishimura J, Hata T, Takemasa I, Mizushima T, Hossain S, Akaike T, Matsuura N, Doki Y, Mori M.
- Journal Title
  
  PLoS One
  
  Volume: 10（3）
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390315
[Journal Article] Concurrent Targeting of KRAS and AKT by MiR-4689 Is a Novel Treatment Against Mutant KRAS Colorectal Cancer.2015
- Author(s)
  Hiraki M, Nishimura J, Takahashi H, Wu X, Takahashi Y, Miyo M, Nishida N, Uemura M, Hata T, Takemasa I, Mizushima T, Soh JW, Doki Y, Mori M, Yamamoto H.
- Journal Title
  
  Mol Ther Nucleic Acids
  
  Volume: 4
- NAID
  130005161476
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390315
[Journal Article] A glucose carbonate apatite complex exhibits in vitro and in vivo anti-　tumour effects.2015
- Author(s)
  Yamamoto H, Wu X, Nakanishi H, Yamamoto Y, Uemura M, Hata T, Nishimura J, Takemasa I, Mizushima T, Sasaki J, Imazato S, Matsuura N, Doki Y, Mori M.
- Journal Title
  
  Sci Rep.
  
  Volume: 5 Pages: 7742-7742
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390315
[Journal Article] A glucose carbonate apatite complex exhibits in vitro and in vivo anti-tumour effects.2015
- Author(s)
  Hirofumi Yamamoto, Xin Wu, Hiroyuki Nakanishi, Yuki Yamamoto, Mamoru Uemura, Taishi Hata, Junichi Nishimura, Ichiro Takemasa, Tsunekazu Mizushima, Jun-Ichi Sasaki, Satoshi Imazato, Nariaki Matsuura, Yuichiro Doki & Masaki Mori.
- Journal Title
  
  Scientific reports
  
  Volume: January Issue: 1 Pages: 1-7
- DOI
  10.1038/srep07742
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13J01119, KAKENHI-PROJECT-25670578, KAKENHI-PROJECT-15K10140
[Journal Article] A Cancer Reprogramming Method Using MicroRNAs as a Novel Therapeutic Approach against Colon Cancer : Research for Reprogramming of Cancer Cells by MicroRNAs.2014
- Author(s)
  Miyazaki S, Yamamoto H, Miyoshi N, Wu X, Ogawa H, Uemura M, Nishimura J, Hata T, Takemasa I, Mizushima T, Konno M, Doki Y, Mori M, Ishii H.
- Journal Title
  
  A Cancer Reprogramming Method Using MicroRNAs as a Novel Therapeutic Approach against Colon Cancer : Research for Reprogramming of Cancer Cells by MicroRNAs.
  
  Volume: Nov 11. [Epub ahead of print]
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390315
[Journal Article] MicroRNA-29b is a Novel Prognostic Marker in Colorectal Cancer.2014
- Author(s)
  Inoue A, Yamamoto H, Uemura M, Nishimura J, Hata T, Takemasa I, Ikenaga M, Ikeda M, Murata K, Mizushima T, Doki Y, Mori M.
- Journal Title
  
  Ann Surg Oncol.
  
  Volume: Dec 4. [Epub ahead of print]
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390315
[Journal Article] SCGB2A1 is a novel prognostic marker for colorectal cancer associated with chemoresistance and radioresistance.2014
- Author(s)
  Munakata K, Uemura M, Takemasa I, Ozaki M, Konno M, Nishimura J, Hata T, Mizushima T, Haraguchi N, Noura S, Ikenaga M, Okamura S, Fukunaga M, Murata K, Yamamoto H, Doki Y, Mori M.
- Journal Title
  
  Int J Oncol
  
  Volume: 44(5) Pages: 1521-1528
- Data Source
  KAKENHI-PROJECT-24390315
[Journal Article] An Impact of Epigenetic Approaches Targeting JARID1B to Modulate Malignant Behaviors of Gastrointestinal Cancer2013
- Author(s)
  Yamamoto H.
- Journal Title
  
  Int J Oncol
  
  Volume: 42 Pages: 549-555
- Data Source
  KAKENHI-PROJECT-23591962
[Journal Article] Ephrin-A1 mRNA is associated with poor prognosis of colorectal cancer2013
- Author(s)
  Yamamoto H., Tei M., Uemura M., Takemasa I., Uemura Y., Murata K., Fukunaga M., Ohue M., Ohnishi T., Ikeda K., Kato T., Okamura S., Ikenaga M., Haraguchi N., Nishimura J., Mizushima T., Mimori K., Doki Y., Mori M.
- Journal Title
  
  Int J Oncol
  
  Pages: 549-555
- Data Source
  KAKENHI-PROJECT-23591962
[Journal Article] Fabrication and intracellular delivery of Doxorubicin/Carbonate Apatite Nanocomposites : Effiect on growth retardation of established Colon Tumor.2013
- Author(s)
  Hossain S, Yamamoto H, Chowdhury EH, Wu x, Akaike T, et.al
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 4 Pages: e60428-e60428
- DOI
  10.1371/journal.pone.0060428
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11F01350, KAKENHI-PLANNED-22130005, KAKENHI-PROJECT-23220014, KAKENHI-PROJECT-24390315
[Journal Article] Depletion of JARID1B induces cellular senescence in human colorectal cancer2013
- Author(s)
  Ohta K., Haraguchi N., Kano Y., Kagawa Y., Konno M., Nishikawa S., Hamabe A., Hasegawa S., Ogawa H., Fukusumi T., Uemura M., Nishimura J., Hata T., Takemasa I., Mizushima T., Noguchi Y., Ozaki M., Kudo T., Sakai D., Satoh T., Fukami M., Ishii M., Yamamoto H., Doki Y., Mori M., Ishii H.
- Journal Title
  
  Int J Oncol
  
  Pages: 1212-1218
- Data Source
  KAKENHI-PROJECT-23591962
[Journal Article] Distinct expression of C4. 4A in colorectal cancer detected by different antibodies.2013
- Author(s)
  Yamamoto H
- Journal Title
  
  Int J Oncol.
  
  Volume: 42 Pages: 197-201
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390315
[Journal Article] PLOD2 induced under hypoxia is a novel prognostic factor for hepatocellular carcinoma after curative resection2012
- Author(s)
  Noda T, Yamamoto H et al
- Journal Title
  
  Liver Int
  
  Volume: 32 Pages: 110-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390360
[Journal Article] C4. 4A is associated with tumor budding and EMT of colorectal cancer2012
- Author(s)
  Oshiro, Yamamoto H et al
- Journal Title
  
  Cancer Science
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390360
[Journal Article] Role of the Hypoxia-Related Gene, JMJD1A, in Hepatocellular Carcinoma2011
- Author(s)
  Yamada D, Kobayashi S, Yamamoto H, et al
- Journal Title
  
  Clinical Impact on Recurrence after Hepatic Resection
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390360
[Journal Article] Hypoxia-inducible adrenomedullin in colorectal cancer2011
- Author(s)
  Uemura M, Yamamoto H et al
- Journal Title
  
  Anticancer Res
  
  Volume: 31(2) Pages: 507-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390360
[Journal Article] Hypoxia-inducible adrenomedullin in colorectal cancer.2011
- Author(s)
  Uemura M, Yamamoto H, Takemasa I, Mimori K, Mizushima T, Ikeda M, Sekimoto M, Dok Y,Mori M.
- Journal Title
  
  Anticancer Res. 2
  
  Pages: 507-514
- Data Source
  KAKENHI-PROJECT-20390357
[Journal Article] Heterogeneity of colorectal cancers and extraction of discriminator gene signatures for personalized prediction of prognosis.2011
- Author(s)
  Miyake M, Takemasa I, Matoba R, Tanino M, Niijima S, Ikeda M, Yamamoto H, Sekimoto M, Kuhara S, Okayama T, Monden M, Matsu bara K, Mori M.
- Journal Title
  
  Int J Clin Oncol. (Epub ahead of print)
- Data Source
  KAKENHI-PROJECT-20390357
[Journal Article] The Significance of PITX2 Overexpression in Human Colorectal Cancer.2011
- Author(s)
  Hirose H, Ishii H, Mimori K, Tanaka F, Takemaa I Mizushima T, Ikeda M,Yamamoto H, Sekimoto M,, Doki Y, Mori M.
- Journal Title
  
  Ann Surg Oncol. (Epub ahead of print)
- Data Source
  KAKENHI-PROJECT-20390357
[Journal Article] Significance of Lgr5(+ve)cancer stem cells in the colon and rectum.2011
- Author(s)
  Takahashi H, Ishii H, Nishida N, Takemasa I, Mizushima T, Ikeda M, Yokobori T, Mimori K, Yamamoto H, Sekimoo M, Dok Y, Mori M.
- Journal Title
  
  Ann Surg Oncol. 18(4)
  
  Pages: 1166-1174
- Data Source
  KAKENHI-PROJECT-20390357
[Journal Article] OSNA-based Novel Molecular Testing for Lymph Node Metastases in Colorectal Cancer Patients : Results from a Multicenter Clinical Performance Study in Japan2011
- Author(s)
  Yamamoto H, et al.
- Journal Title
  
  Annals of Surgical Oncology
  
  Volume: (Epub)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390360
[Journal Article] OSNA-based Novel Molecular Testing for Lymph Node Metastases in Colorectal Cancer Patients : Results from a Multicenter ClinicalPerformance Study in Japan2011
- Author(s)
  Yamamoto H et al
- Journal Title
  
  Annals of Surgical Oncology
  
  Volume: 18(7) Pages: 1891-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390360
[Journal Article] Jumonji domain containing 1A is a novel prognostic marker for colorectal cancer : in vivo identification from hypoxic tumor cells2010
- Author(s)
  Uemura M, Yamamoto H, et al.
- Journal Title
  
  Clin Cancer Res
  
  Volume: 16 Pages: 4636-4646
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390360
[Journal Article] Expression of C4.4A at the invasive front is a novel prognostic marker for disease recurrence of colorectal cancer.2010
- Author(s)
  Konishi K, Yamamoto H, et al.
- Journal Title
  
  Cancer Science
  
  Volume: 101 Pages: 2269-2277
- NAID
  10027832873
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390360
[Journal Article] Expression of C4. 4A at the invasive front is a novel prognostic marker for disease recurrence of colorectal cancer2010
- Author(s)
  Konishi K, Yamamoto H et al
- Journal Title
  
  Cancer Science
  
  Volume: 101 Pages: 2269-77
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390360
[Journal Article] Jumonji domain containing 1A is a novel prognostic marker for colorectal cancer : in vivo identification from hypoxic tumor cells2010
- Author(s)
  Uemura M, Yamamoto H et al
- Journal Title
  
  Clin Cancer Res
  
  Volume: 16 Pages: 4636-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390360
[Journal Article] Expression of C4. 4A at the invasive front is a novel prognostic marker for disease recurrence of colorectal cancer.2010
- Author(s)
  Konishi K, Yamamoto H, Mimori K, Takemasa I, Mizushima T, Ikeda M, Sekimoto M, Matsuura N, Takao T, Doki Y, Mori M.
- Journal Title
  
  CancerSci. 101(10)
  
  Pages: 2269-2277
- Data Source
  KAKENHI-PROJECT-20390357
[Journal Article] 大腸癌の個別化医療に向けて2008
- Author(s)
  竹政伊知朗、池田正孝、山本浩文、関本貢嗣、森正樹、門田守人
- Journal Title
  
  Frontiers in Gastroenterology. 13(3)
  
  Pages: 224-231
- Data Source
  KAKENHI-PROJECT-20390357
[Journal Article] Gene expression of colorectal cancer : Preoperative genetic diagnosis usinscopic biopsies.2008
- Author(s)
  Komori T., Takemasa I., Yamasaki M., Motoori M., Kato T., Kikkawa N., Kawaguchi N., Ikeda M., Yamamoto H., Semoto M., Matsubara K., Matsuura N., onden M.
- Journal Title
  
  Int J Oncol. 32(2)
  
  Pages: 367-375
- Data Source
  KAKENHI-PROJECT-20390357
[Journal Article] Overexpression of MT1-MMP is insufficient to increase experimentalliver metastasis of human colon cancer cells.2008
- Author(s)
  Yamamoto H., Noura S., Okami J., Uemura M., Takemasa I., Ikeda M., Ishii H., Sekimoto M., Matsuura N., Monden M., Mori M.
- Journal Title
  
  Int J Mol Med. 22(6)
  
  Pages: 757-761
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659322
[Journal Article] Aberrant Expression of Connexin 26 Is Associated with Lung Metastasis of Colorectal Cancer.2008
- Author(s)
  Ezumi K., Yamamoto H., Murata K., Higashiyama M., Damdinsuren B., Nakamura Y., Kyo N., Okami J., Ngan Cy., Takemasa I., Ikcda M., Sekimoto M., Matsuura N., Nojima H., Monden M.
- Journal Title
  
  Clin Cancer Res. 14(3)
  
  Pages: 677-684
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390357
[Journal Article] 大腸癌の個別化医療に向けて2008
- Author(s)
  竹政伊知朗, 池田正孝, 山本活文, 関本貢嗣, 森正樹, 門田守人
- Journal Title
  
  Frontiers in Gastroenterology 13(3)
  
  Pages: 224-231
- Data Source
  KAKENHI-PROJECT-20390357
[Journal Article] 転移因手を標的とした肝転移の治療戦略2008
- Author(s)
  山本浩文, 竹政伊知朗, 池田正孝, 関本貢嗣, 門田守人
- Journal Title
  
  Biotherapy 22(2)
  
  Pages: 96-104
- Data Source
  KAKENHI-PROJECT-20390357
[Journal Article] Gene expression of colorectal cancer : Preoperative genetic diagnosis using endoscopic biopsies.2008
- Author(s)
  Komori T., Takemasa I, Yamasaki M., Motoori M., Kato T., Kikkawa N., Kawaguchi N., Ikeda M., Yamamoto H., SekimotoM., Matsubara K., Matsuura N., Monden M.
- Journal Title
  
  Int J Oncol. 32(2)
  
  Pages: 367-375
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390357
[Journal Article] Gene expression of colorectal cancer : Preoperative genetic diagnosis using endoscopic biopsies.2008
- Author(s)
  Komori T., Takemasa I., Yamasaki M., Motoori M., Kato T., Kikkawa N., Kawaguchi N., Ikeda M., Yamamoto H., Sekimoto M., Matsubara K., Matsuura N., Monden M.
- Journal Title
  
  Int J Oncol. 32(2)
  
  Pages: 367-375
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659322
[Journal Article] Expression level of hepatoma-derived growth factor correlates with tumor recurrence of esophageal carcinoma.2007
- Author(s)
  Yamamoto S., Tomita Y., Hoshida Y., Morii E., Yasuda T., Doki., Aozasa K., Uyama H., Nakamura., Monden M.
- Journal Title
  
  Ann Surg Oncol 14(7)
  
  Pages: 2141-2149
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659322
[Journal Article] Construction of a novel DNA decoy that inhibits the oncogenic beta-catenin/T-cell factor pathway.2006
- Author(s)
  Seki Y, Yamamoto H, Yee Ngan C, Yasui M, Tomita N, Kitani K, Takemasa I, Ikeda M, Sekimoto M, Matsuura N, Albanese C, Kaneda Y, Pestell RG, Monden M.
- Journal Title
  
  Mol Cancer Ther 5(4)
  
  Pages: 985-994
- Data Source
  KAKENHI-PROJECT-17591396
[Journal Article] Expression and Mutation of SMAD4 in poorly Differentiated Carcinoma and Signet-ring Cell Carcinoma of the Colorectum.2006
- Author(s)
  Seshimo I, Yamamoto H., Mishima H., Kurata A., Suzuki R., Ezumi K., Takemasa I., Ikeda M., Fukushima T., Tujinaka T., Sekimoto M., Kikkawa N., Takenoshita S., Monden M
- Journal Title
  
  J. Exp. Clin. Cancer Res 25
  
  Pages: 433-442
- Data Source
  KAKENHI-PROJECT-17591396
[Journal Article] Expression pattern of angiogenic factors and prognosis after hepatic resection in hepatocellular carcinoma : importance of angiopoietin-2 and hypoxia-induced factor-1 alpha.2006
- Author(s)
  Wada H., Nagano H., Yamamoto H., Yang Y., Kondo M., Ota H., Nakamura M., Yoshioka S., Kato H., Damdinsuren B., Tang D., Marubashi S., Miyamoto A., Takeda Y., Umeshita K., Nakamori S., Sakon M., Dono K., Wakasa K., Monden M.
- Journal Title
  
  Liver International 26
  
  Pages: 414-423
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390367
[Journal Article] Angiogenesis in cholangiocellular carcinoma : Expression of vascular endothelial growth factor, angiopoietin-1/2, thrombospodin-1 and clinicopathological significance.2006
- Author(s)
  Tang D, Nagano H, Yamamoto H, Wada H, Nakamura M, Kondo M, Ota H, Yoshioka S, Kato H, Damdinsuren B, Marubashi S, Miyamoto A, Takeda Y, Umeshita K, Dono K, Wakasa K, Monden M.
- Journal Title
  
  Oncology Reports 15
  
  Pages: 525-532
- Data Source
  KAKENHI-PROJECT-17390367
[Journal Article] Hypoxia-induced up-regulation of angiopoietin-2 in colorectal cancer.2006
- Author(s)
  Gu J., Yamamoto H., Ogawa M., Ngan C.Y., Danno K., Hemmi H., Kyo N., Takemasa I., Ikeda M., Sekimoto M., Monden M.
- Journal Title
  
  Oncol Rep 15(4)
  
  Pages: 779-783
- Data Source
  KAKENHI-PROJECT-17591396
[Journal Article] Low-dose oxaliplatin enhances the antitumor efficacy of paclitaxel in human gastric cancer cell lines.2006
- Author(s)
  Gu J., Yamamoto H., Lu X., Ngan CY., Tsujino T., Konishi K., Takemasa I., Ikeda M., Nagata H., Hashimoto S., Matsuzaki T., Sekimoto M., Takagi A., Monden M.
- Journal Title
  
  Digestion. 74(1)
  
  Pages: 19-27
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591396
[Journal Article] Antisense to cyclin DI inhibits vascular endothelial growth factor-stimulated growth of vascular endothelial cells : implication of tumor vascularization.2006
- Author(s)
  Yasui M, Yamamoto H., Ngan CY., Damdinsuren B., Sugita Y., Fukunaga H., Gu J., Maeda M., Takemasa I., Ikeda M., Fujio Y, Sekimoto M., Matsuura N., Weinstein IB., Monden M.
- Journal Title
  
  Clin Cancer Res. 12(15)
  
  Pages: 4720-4729
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591396
[Journal Article] Expression of PPARdelta in multistage carcinogenesis of the colorectum : implications of malignant cancer morphology.2006
- Author(s)
  Takayama 0., Yamamoto H., Damdinsuren B., Sugita Y., Ngan CY., Xu X., Tsujino T., Takemasa I., Ikeda M., Sekimoto M., Matsuura N., Monden M.
- Journal Title
  
  Br J Cancer 95(7)
  
  Pages: 889-895
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591396
[Journal Article] Angiogenesis in cholangiocellular carcinoma : Expression of vascular endothelial growth factor, angiopoietin-1/2, thrombospondin-1 and clinicopathological significance.2006
- Author(s)
  Tang D., Nagano H., Yamamoto H., Wada H., Nakamura M., Kondo M., Ota H., Yoshioka S., Kato H., Damdinsuren B., Marubashi S., Miyamoto A., Takeda Y., Umeshita K., Dono K., Wakasa K., Monden M.
- Journal Title
  
  Oncol Rep 15(3)
  
  Pages: 525-532
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390367
[Journal Article] Angiogenesis in cholangiocellular carcinoma : Expression of vascular endothelial growth factor, angiopoietin-1/2, thrombospondin-1 and clinicopathological significance.2006
- Author(s)
  Tang D., Nagano H., Yamamoto H., Wada H., Nakamura M., Kondo M., Ota H., Yoshioka S., Kato H., Damdinsuren B., Marubashi S., Miyamoto A., Takeda Y., Umeshita K., Dono K., Wakasa K., Monden M.
- Journal Title
  
  Oncol Rep. 15(3)
  
  Pages: 525-532
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390367
[Journal Article] Correlation of GLUT-1 Overexpression, Tumor Size, and Depth of Invasion with 18F-2-fluoro-2-deoxy-D : -glucose Uptake by Positron Emission Tomography in Colorectal Cancer.2006
- Author(s)
  Gu J., Yamamoto H, Fukunaga H, Danno K, Takemasa I, Ikeda M, Tatsumi M, Sekimoto M, Hatazawa J, Nishimura T, Monden M.
- Journal Title
  
  Dig Dis Sci. 11(3)
  
  Pages: 2198-205
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591396
[Journal Article] Correlation of GLUT-1 Overexpression, Tumor Size, and Depth of Invasion with 18F-2-fluoro-2-deoxy-D : -glucose Uptake by Positron Emission Tomography in Colorectal Cancer.2006
- Author(s)
  Gu J., Yamamoto H, Fukunaga H, Danno K, Takemasa I, Ikeda M, Tatsumi M, Sekimoto M, Hatazawa J, Nishimura T, Monden M.
- Journal Title
  
  Dig Dis Sci 11(3)
  
  Pages: 2198-2205
- Data Source
  KAKENHI-PROJECT-17591396
[Journal Article] Low-dose oxaliplatin enhances the antitumor efficacy of paclitaxel in human gastric cancer cell lines.2006
- Author(s)
  Gu J., Yamamoto H., Lu X., Ngan CY., Tsujino T., Konishi K., Takemasa I., Ikeda M., Nagata H., Hashimoto S., Matsuzaki T., Sekimoto M., Takagi A., Monden M.
- Journal Title
  
  Digestion 74(1)
  
  Pages: 19-27
- Data Source
  KAKENHI-PROJECT-17591396
[Journal Article] Expression of PPARdelta in multistage carcinogenesis of the colorectum : implications of malignant cancer morphology.2006
- Author(s)
  Takayama O., Yamamoto H., Damdinsuren B., Sugita Y., Ngan CY., Xu X., Tsujino T., Takemasa I, Ikeda M., Sekimoto M., Matsuura N., Monden M.
- Journal Title
  
  Br J Cancer 95(7)
  
  Pages: 889-895
- Data Source
  KAKENHI-PROJECT-17591396
[Journal Article] Antisense to cyclin D1 inhibits vascular endothelial growth factor-stimulated growth of vascular endothelial cells : implication of tumor vascularization.2006
- Author(s)
  Yasui M, Yamamoto H., Ngan CY., Damdinsuren B., Sugita Y., Fukunaga H., Gu J., Maeda M., Takemasa I., Ikeda M., Fujio Y., Sekimoto M., Matsuura N., Weinstein IB., Monden M.
- Journal Title
  
  Clin Cancer Res 12(15)
  
  Pages: 4720-4729
- Data Source
  KAKENHI-PROJECT-17591396
[Journal Article] Construction of a novel DNA decoy that inhibits the oncogenic beta-catenin/T-cell factor pathway.2006
- Author(s)
  Seki Y, Yamamoto H, Yee Ngan C, Yasui M, Tomita N, Kitani K, Takemasa I, Ikeda M, Sekimoto M, Matsuura N, Albanese C, Kaneda Y, Pestell RG, Monden M.
- Journal Title
  
  Mol Cancer Ther. 5(4)
  
  Pages: 985-994
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591396
[Journal Article] Hypoxia-induced up-regulation of angiopoietin-2 in colorectal cancer.2006
- Author(s)
  Gu J., Yamamoto H., Ogawa M., Ngan C.Y., Danno K., Hemmi H., Kyo N., Takemasa I., Ikeda M., Sekimoto M., Monden M.
- Journal Title
  
  Oncol Rep. 15(4)
  
  Pages: 779-783
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591396
[Journal Article] Expression and Mutation of SMAD4 in poorly Differentiated Carcinoma and Signet-ring Cell Carcinoma of the Colorectum.2006
- Author(s)
  Seshimo I, Yamamoto H., Mishima H., Kurata A., Suzuki R., Ezumi K., Takemasa 1., Ikeda M., Fukushima T., Tujinaka T., Sekimoto M., Kikkawa N., Takenoshita S., Monden M.
- Journal Title
  
  J.Exp.Clin.Cancer Res 25
  
  Pages: 433-442
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591396
[Journal Article] Combination of interferon alpha and 5-fluorouracil induces apoptosis through interferon alpha/beta receptor in human hepatocellular carcinoma cells.2005
- Author(s)
  Kondo M, Nagano H, Wada H, Damdinsuren B, Yamamoto H, Hiraoka N, Eguchi H, Miyamoto A, Yamamoto T, Ota H, Nakamura M, Marubashi S, Dono K, Umeshita K, Nakamori S, Sakon M, Monden M.
- Journal Title
  
  Clinical Cancer Research 11
  
  Pages: 1277-1286
- Data Source
  KAKENHI-PROJECT-17390367
[Journal Article] Association between recurrence of hepatocellular carcinoma and alpha-fetoprotein messenger RNA levels in peripheral blood.2005
- Author(s)
  Morimoto O., Nagano H., Miyamoto A., Fujiwara Y., Kondo M., Yamamoto T., Ota H., Nakamura M., Wada H., Damdinsuren B., Marubashi S., Dono K., Umeshita K., Nakamori S., Sakon M., Monden M.
- Journal Title
  
  Surgery Today 35(12)
  
  Pages: 1033-1041
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390367
[Journal Article] Association between recurrence of hepatocellular carcinoma and alpha-fetoprotein messenger RNA levels in peripheral blood.2005
- Author(s)
  Morimoto O., Nagano H., Miyamoto A., Fujiwara Y., Kondo M., Yamamoto T., Ota H., Nakamura M., Wada H., Damdinsuren B., Marubashi S., Dono K., Umeshita K., Nakamori S., Sakon M., Monden M.
- Journal Title
  
  Surgery Today. 35(12)
  
  Pages: 1033-1041
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390367
[Journal Article] DNAマイクロアレイを用いたトランスクリプトーム解析による腫瘍マーカーの探索2005
- Author(s)
  小森孝通, 竹政伊知朗, 山崎誠, 本告正明, 吉岡慎一, 小山太一, 池田正孝, 山本浩文, 関本貢嗣, (松原謙一), 門田守人
- Journal Title
  
  日本分子腫瘍マーカー研究会誌 20
  
  Pages: 76-77
- NAID
  130004436355
- Data Source
  KAKENHI-PROJECT-15209040
[Journal Article] DNAマイクロアレイを用いたトランスクリプトーム解析による腫瘍マーカーの探索2005
- Author(s)
  小森孝通, 竹政伊知朗, 山崎誠, 本告正明, 吉岡慎一, 小山太一, 池田正孝, 山本浩文, 関本貢嗣, (松原謙一), 門田守人
- Journal Title
  
  日本分子腫瘍マーカー研究会誌 20
  
  Pages: 76-77
- NAID
  130004436355
- Data Source
  KAKENHI-PROJECT-17591396
[Journal Article] Expression of ID proteins in human hepatocellular carcinoma : Relevance to tumor dedifferentiation.2005
- Author(s)
  Damdinsuren B, Nagano H, Kondo M, Yamamoto H, Hiraoka N, Yamamoto T, Marubashi S, Miyamoto A, Umeshita K, Dono K, Nakamori S, Wakasa K, Sakon M, Monden M.
- Journal Title
  
  Int J Oncol 26
  
  Pages: 319-327
- Data Source
  KAKENHI-PROJECT-17390367
[Journal Article] Association between tumor recurrence after surgery in patients with hepatocellular carcinoma and measurement of alpha-fetoprotein mRNA in peripheral blood but not bone marrow2005
- Author(s)
  Morimoto O, Nagano H, Miyamoto A, Fujiwara Y, Kondo M, Yamamoto T, Ota H, Nakamura M, Wada H, Damdinsuren B, Marubashi S, Dono K, Umeshita K, Nakamori S, Sakon M, Monden M.
- Journal Title
  
  Surgery Today 35(12)
  
  Pages: 1033-1041
- Data Source
  KAKENHI-PROJECT-17390367
[Journal Article] Treatment of hepatocellular carcinoma with major portal vein thrombosis by combination of subcutaneous interferon-α and intra-arterial 5-fluorouracil. Role of expression of type 1 interferon receptor2005
- Author(s)
  Ota H, Nagano H, Sakon M, Eguchi H, Kondo M, Yamamoto T, Nakamura M, Damdinsuren B, Wada H, Marubashi, Miyamoto A, Dono K, Umeshita K, Nakamori S, Wakasa K, Monden M
- Journal Title
  
  Br J Cancer 93(5)
  
  Pages: 557-564
- Data Source
  KAKENHI-PROJECT-17390367
[Journal Article] Micrometastasis of gastrointestinal cancer2004
- Author(s)
  Fuzie Y, Yamamoto H. et al.
- Journal Title
  
  GEKA 66(5)
  
  Pages: 501-506
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591402
[Journal Article] Wntシグナルを標的とした治療2004
- Author(s)
  関洋介, 山本清文, 他
- Journal Title
  
  現代医療 36(7)
  
  Pages: 1373-1380
- Data Source
  KAKENHI-PROJECT-16591313
[Journal Article] Hepatic resection followed by IFN-α and 5-FU for advanced hepatocellular carcinoma with tumor thrombus in the major portal branch.
- Author(s)
  Nagano H, Sakon M, Eguchi H, Kondo M, Yamamoto T, Ota H, Nakamura M, Wada H, Bazarragcha D, Marubashi S, Miyamoto A, Takeda Y, Keizo Dono, Umeshita K, Nakamori S, Monden M
- Journal Title
  
  Hepatogastroenterology (in press)
- Data Source
  KAKENHI-PROJECT-17390367
[Journal Article] Antisense to Cyclin D1 Inhibits VEGF-Stimulated Growth of Vascular Endothelial Cells. Implication of Tumor Vascularization.
- Author(s)
  Yasui M., Yamamoto., et al.
- Journal Title
  
  Clin Cancer Res. (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591313
[Journal Article] Expression pattern of angiogenic factors and prognosis after hepatic resection in hepatocellular carcinoma : Importance of angiopoietin-2 and hypoxia-induced factor-1□
- Author(s)
  Wada H, Nagano H, Yamamoto H, Yang Y, Kondo M, Ota H, Nakamura M, Yoshioka S, Kato H, Damdinsuren B, Tang D, Marubashi S, Miyamoto A, Takeda Y, Umeshita K, Nakamori S, Sakon M, Dono K, Wakasa K, Monden M.
- Journal Title
  
  Liver International (in press)
- Data Source
  KAKENHI-PROJECT-17390367
[Journal Article] 転移因子を標的とした肝転移の治療戦略
- Author(s)
  山本浩文、竹政伊知朗、池田正孝、関本貢嗣、門田守人
- Journal Title
  
  Biotherapy 22(2)
  
  Pages: 96-104
- Data Source
  KAKENHI-PROJECT-20390357
[Journal Article] Antisense to Cyclin D1 Inhibits VEGF-Stimulated Growth of Vascular Endothelial Cells. Implication of Tumor Vascularization
- Author(s)
  Yasui M, Yamamoto H, Ngan Chew Yee, Bazarragchaa D, Sugita Y, Fukunaga H, Gu J, Maeda M, Takemsa I, Ikeda M, Fujio Y, Sekimoto M. Matsuura N, I.Bernard Weinstein, Monden M.
- Journal Title
  
  Clinical Cancer Research (in press)
- Data Source
  KAKENHI-PROJECT-16591313
[Journal Article] Construction of a novel DNA decoy that inhibits the oncogenic β-catenin/TCF pathway
- Author(s)
  Seki Y, Yamamoto H, Ngan Chew Yee, Yasui M, Tomita N, Kitani K, Takemasa I, Ikeda M, Sekimoto M, Matsuura N, Chris Albanese, Kaneda Y, Richard G Pestell, Monden M.
- Journal Title
  
  Molecular Cancer Therapeutics (in press)
- Data Source
  KAKENHI-PROJECT-16591313
[Journal Article] Overexpression of MT3-MMP in hepatocellular carcinoma correlates with capsular invasion.
- Author(s)
  Arai I, Nagano H, Kendo M, Yamamoto H, Hiraoka N, Sugita Y, Ota H, Yoshioka S, Nakamura M, Wada H, Damdinsuren B, Kato H, Marubashi S, Miyamoto A, Takeda Y, Dono K, Umeshita K, Nakamori S, Wakasa K, Sakon M, Monden M.
- Journal Title
  
  Hepatogastroenterology (in press)
- Data Source
  KAKENHI-PROJECT-17390367
[Journal Article] Construction of a novel DNA decoy that inhibits the oncogenic □-catenin/TCF pathway.
- Author(s)
  Seki Y., Yamamoto., et al.
- Journal Title
  
  Mol Cancer Ther. (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591313
[Journal Article] Antisense to Cyclin D1 Inhibits VEGF-Stimulated Growth of Vascular Endothelial Cells. Implication of Tumor Vascularization.
- Author(s)
  Yasui M., Yamamoto H., et al.
- Journal Title
  
  Clin Cancer Res. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591313
[Patent] 炎症性腸疾患の予防又は治療剤2017
- Inventor(s)
  山本浩文、他
- Industrial Property Rights Holder
  山本浩文、他
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-16K15590
[Patent] 大腸癌の治療剤2014
- Inventor(s)
  山本浩文、森正樹、土岐祐一郎、西村潤一
- Industrial Property Rights Holder
  山本浩文、森正樹、土岐祐一郎、西村潤一
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-041768
- Filing Date
  2014-03-04
- Data Source
  KAKENHI-PROJECT-24659608
[Patent] グルコースと炭酸アパタイトを使用した抗癌剤2014
- Inventor(s)
  山本浩文　他
- Industrial Property Rights Holder
  山本浩文　他
- Industrial Property Rights Type
  特許
- Filing Date
  2014-02-20
- Data Source
  KAKENHI-PROJECT-25670578
[Patent] 大腸癌の治療剤2014
- Inventor(s)
  山本浩文森正樹土岐祐一郎西村潤一
- Industrial Property Rights Holder
  山本浩文森正樹土岐祐一郎西村潤一
- Industrial Property Rights Type
  特許
- Filing Date
  2014
- Data Source
  KAKENHI-PROJECT-24659608
[Patent] 抗腫瘍効果を有する新規microRNA2014
- Inventor(s)
  山本浩文　他
- Industrial Property Rights Holder
  山本浩文　他
- Industrial Property Rights Type
  特許
- Filing Date
  2014-03-04
- Data Source
  KAKENHI-PROJECT-24390315
[Patent] Pharmaceutical composition for targeting cancer using carbonate apatite nanoparticle2013
- Inventor(s)
  Yamamoto H et al.
- Industrial Property Rights Holder
  Yamamoto H et al.
- Industrial Property Rights Type
  特許
- Filing Date
  2013-08-27
- Overseas
- Data Source
  KAKENHI-PROJECT-24390315
[Patent] miR-340を用いた大腸癌の治療剤2013
- Inventor(s)
  山本浩文　他
- Industrial Property Rights Holder
  山本浩文　他
- Industrial Property Rights Type
  特許
- Filing Date
  2013-11-05
- Data Source
  KAKENHI-PROJECT-24390315
[Patent] 癌予後判定可能な抗体、および癌予後判定方法2011
- Inventor(s)
  山本浩文
- Industrial Property Rights Holder
  大阪大学
- Filing Date
  2011-06-15
- Overseas
- Data Source
  KAKENHI-PROJECT-21390360
[Patent] 癌予後判定可能な抗体、および癌予後判定方法2011
- Inventor(s)
  山本浩文
- Industrial Property Rights Holder
  大阪大学
- Filing Date
  2011-06-15
- Overseas
- Data Source
  KAKENHI-PROJECT-21390360
[Patent] 癌予後判定可能な抗体、および癌予後判定方法2010
- Inventor(s)
  山本浩文
- Industrial Property Rights Holder
  大阪大学
- Filing Date
  2010-06-15
- Data Source
  KAKENHI-PROJECT-21390360
[Patent] 癌予後判定可能な抗体、および癌予後判定方法2010
- Inventor(s)
  山本浩文
- Industrial Property Rights Holder
  大阪大学
- Industrial Property Number
  2010-136621
- Filing Date
  2010-06-15
- Data Source
  KAKENHI-PROJECT-21390360
[Presentation] 大腸癌の発生・進展における MAF 遺伝子の役割解明2021
- Author(s)
  板倉弘明、奥崎大介、横山雄起、関戸悠紀、波多豪、荻野崇之、三吉範克、高橋秀和、植村守、土岐祐一郎、江口英利、山本浩文
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K08356
[Presentation] 核酸医療のための新しいリン酸カルシウム法の確立2021
- Author(s)
  山本浩文
- Organizer
  第30回日本がん転移学会学術集会
- Data Source
  KAKENHI-PROJECT-21H04831
[Presentation] Brand-new calcium phosphate method as DDS for nucleic acid medicine2021
- Author(s)
  Hirofumi Yamamoto
- Organizer
  Nucleic Acid Therapie: CSHL Virtual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04059
[Presentation] 複合免疫療法と温熱療法2019
- Author(s)
  久保田結衣, 武田力, 武田和, 野田剛広, 服部宣明, 中村華奈, 安田知世, 長谷川武夫, 横山雄起, 山本浩文, 武田寛子
- Organizer
  第40回日本癌免疫外科研究会
- Data Source
  KAKENHI-PROJECT-17K10548
[Presentation] 大腸癌における長鎖非コードRNAの機能解析2019
- Author(s)
  大塚正久, 原口直紹, 鈴木陽三, 高橋秀和, 種村匡弘, 赤松大樹, 水島恒和, 土岐祐一郎, 森正樹, 山本浩文
- Organizer
  第74回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-17K07196
[Presentation] ネオアンチゲン・免疫チェックポイント阻害薬そして温熱療法2019
- Author(s)
  武田力, 久保田結衣, 武田和, 安田知世, 窪田瑛佳, 服部宣明, 中村華奈, 武田寛子, 長谷川武夫, 中村祐輔, 横山雄起, 山本浩文
- Organizer
  第32回日本バイオセラピィ学会学術集会総会
- Data Source
  KAKENHI-PROJECT-17K10548
[Presentation] 温熱による細胞性免疫誘導と免疫チェックポイント阻害剤併用の意義2019
- Author(s)
  久保田結衣, 武田力, 長谷川武夫, 武田寛子, 安田知世, 横山雄起, 山本浩文
- Organizer
  第30回日本消化器癌発生学会総会
- Data Source
  KAKENHI-PROJECT-17K10548
[Presentation] Long Noncoding RNA Regulates Cancer Stem Cells in Colorectal Cancer2019
- Author(s)
  Masahisa Ohtsuka, Naotsugu Haraguchi, Norikatsu Miyoshi, Hidekazu Takahashi, Taishi Hata, Chu Matsuda, Masahiro Tanemura, Hiroki Akamatsu, Tsunekazu Mizushima, Yuichiro Doki, Masaki Mori, Hirofumi Yamamoto
- Organizer
  11th AACR-JCA Joint Conference on Breakthroughs in Cancer Research: Biology to Precision Medicine
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07196
[Presentation] 大腸癌における癌幹細胞関連長鎖非コードRNAについての検討2019
- Author(s)
  大塚正久, 原口直紹, 池嶋遼, 大原信福, 三吉範克, 高橋秀和, 畑泰司, 松田宙, 種村匡弘, 赤松大樹, 水島恒和, 土岐祐一郎, 森正樹, 山本浩文
- Organizer
  第119回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-17K07196
[Presentation] The effect of FGF2 and integrin on epithelial-mesenchymal transition2019
- Author(s)
  藤本彩花、森誠司、五島碧、横山雄起、松浦成昭、高田義一、山本浩文
- Organizer
  第78回　日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K08775
[Presentation] 難治性癌に対する核酸医薬MIRTXの抗腫瘍効果の検討2019
- Author(s)
  五島碧, 横山雄起, 入江侑馬, 廣瀬遥香, 木島貴志, 三好康雄, 柴田理志, 山本浩文
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18H04059
[Presentation] 膵癌細胞におけるmiR-29b-1-5pの抗腫瘍効果の検討2019
- Author(s)
  入江侑馬, 横山雄起, 石川翔, 銭雅敏, 廣瀬遥香, 山本浩文
- Organizer
  第30回日本消化器癌発生学会総会
- Data Source
  KAKENHI-PROJECT-18H04059
[Presentation] 分子温熱療法の可能性2019
- Author(s)
  安田知世, 久保田結衣, 横山雄起, 廣瀬遥香, 柴田理志, 長谷川武夫, 武田力, 山本浩文
- Organizer
  第21回関西ハイパーサーミア研究会
- Data Source
  KAKENHI-PROJECT-17K10548
[Presentation] 令和新時代の温熱療法の発展は（免疫チェックポイント阻害薬とネオアンチゲンの新時代において）2019
- Author(s)
  武田力, 久保田結衣, 武田和, 安田知世, 佐藤光幸, 中野義人, 中村華奈, 武田寛子, 長谷川武夫, 横山雄起, 山本浩文
- Organizer
  第21回関西ハイパーサーミア研究会
- Data Source
  KAKENHI-PROJECT-17K10548
[Presentation] FGF2とインテグリンの結合が乳腺上皮細胞のEMT進行に及ぼす影響2019
- Author(s)
  藤本彩花、森誠司、五島碧、横山雄起、松浦成昭、山本浩文
- Organizer
  第42回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K08775
[Presentation] ホモロジー概念を用いた大腸癌発生過程の数理学的病理診断2019
- Author(s)
  松田美和、中根和昭、横山雄起、南雲サチ子、森井英一、山本浩文
- Organizer
  第30回日本消化器癌発生学会総会
- Data Source
  KAKENHI-PROJECT-18H03333
[Presentation] PD-L1 siRNAによる核酸治療の可能性2018
- Author(s)
  久保田結衣、吉岡靖雄、横山雄起、呉しん、武田力、山本浩文
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K10548
[Presentation] FGF2とインテグリンの結合は乳癌の浸潤能を亢進させる2018
- Author(s)
  五島碧、森誠司、横山雄起、松浦成昭、山本浩文
- Organizer
  第77回　日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K08775
[Presentation] 大腸癌に対するICG光線力学療法2018
- Author(s)
  太田みのり、玉井皓己、横山雄起、井上彬、畑泰司、松田宙、水島恒和、土岐祐一郎、森正樹、山本浩文
- Organizer
  第27回日本がん転移学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-18H04059
[Presentation] KRAS変異型大腸癌に対するmiR-29b-1-5pの抗腫瘍効果の検討2018
- Author(s)
  石川翔、横山雄起、井上彬、三吉範克、高橋秀和、原口直紹、水島恒和、土岐祐一郎、森正樹、山本浩文
- Organizer
  第27回日本がん転移学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-18H04059
[Presentation] Interaction between FGF2 and integrin enhances invasion ability of breast cancer cells.2018
- Author(s)
  五島碧、森誠司、横山雄起、松浦成昭、山本浩文
- Organizer
  第41回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K08775
[Presentation] 免疫チェックポイント抗体治療における温熱療法の意義2018
- Author(s)
  久保田結衣、武田力、武田和、服部宣明、中野義人、佐藤光幸、田中千栄里、武田寛子、長谷川武夫、横山雄起、山本浩文
- Organizer
  第20回　関西ハイパーサーミア研究会
- Data Source
  KAKENHI-PROJECT-17K10548
[Presentation] 免疫チェックポイント抗体と樹状細胞を併用した複合免疫療法の効果2018
- Author(s)
  武田力、久保田結衣、武田和、安田知世、武田寛子、横山雄起、山本浩文
- Organizer
  第7回日本免疫・細胞治療学会総会
- Data Source
  KAKENHI-PROJECT-17K10548
[Presentation] 接着分子インテグリンと増殖因子の相互作用が癌進展において果たす役割2018
- Author(s)
  森誠司、松浦成昭、高田義一、山本浩文
- Organizer
  第77回　日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K08775
[Presentation] 免疫チェックポイント抗体治療における温熱療法の意義2018
- Author(s)
  久保田結衣、武田力、安田知世、武田和、服部宣明、中村華奈、田中千栄里、武田寛子、長谷川武夫、横山雄起、山本浩文
- Organizer
  第31回　日本バイオセラピィ学会学術集会総会
- Data Source
  KAKENHI-PROJECT-17K10548
[Presentation] 免疫チェックポイント抗体と樹状細胞療法との複合免疫療法において温熱療法は役に立つか？2018
- Author(s)
  武田力、武田和、久保田結衣、本庄郁恵、森田祐子、野上祐子、東佐和子、吉岡ありさ、武田寛子、横山雄起、山本浩文
- Organizer
  第20回　関西ハイパーサーミア研究会
- Data Source
  KAKENHI-PROJECT-17K10548
[Presentation] EPRを促進するsCAの中につめない利用法2018
- Author(s)
  山本浩文、森正樹
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18H04059
[Presentation] 免疫チェックポイント抗体と樹状細胞を併用した複合免疫療法における温熱療法の意義2018
- Author(s)
  武田力、久保田結衣、武田和、田中千栄里、武田寛子、服部宣明、長谷川武夫、横山雄起、山本浩文
- Organizer
  第35回　日本ハイパーサーミア学会
- Data Source
  KAKENHI-PROJECT-17K10548
[Presentation] 免疫チェックポイント抗体と樹状細胞を併用した複合免疫療法の効果2018
- Author(s)
  武田力、久保田結衣、武田和、安田知世、武田寛子、横山雄起、山本浩文
- Organizer
  第31回　日本バイオセラピィ学会学術集会総会
- Data Source
  KAKENHI-PROJECT-17K10548
[Presentation] E-cad-Fc コーティングによる癌幹細胞性質の増強2018
- Author(s)
  銭雅敏、呉しん、横山雄起、田口真衣、王かき、廣瀬遥香、森誠司、松浦成昭、山本浩文
- Organizer
  第77回　日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K08775
[Presentation] 低侵襲治療としての大腸癌に対するICG光線力学療法2018
- Author(s)
  武田昂樹、畑泰司、玉井皓己、太田みのり、横山雄起、高橋秀和、三吉範克、原口直紹、松田宙、水島恒和、土岐祐一郎、森正樹、山本浩文
- Organizer
  第118回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-15H04920
[Presentation] 中皮細胞はスフェロイド中の卵巣癌細胞の幹細胞様形質を促進する2018
- Author(s)
  宍戸明美、森誠司、横山雄起、濱田吉之輔、皆巳和賢、銭雅敏、王かき、廣瀬遥香、呉しん、河口直正、南雲サチ子、松浦成昭、山本浩文
- Organizer
  第77回　日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K08775
[Presentation] BET阻害剤はALDH1A1遺伝子のスーパーエンハンサーを標的として卵巣癌のALDH活性を抑制する2018
- Author(s)
  横山雄起、武田和、北川公望、森誠司、水島恒和、森正樹、松浦成昭、山本浩文
- Organizer
  第77回　日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K08775
[Presentation] FGF-2とインテグリンαvβ3の相互作用が血管新生に及ぼす影響2017
- Author(s)
  羽鳥暢晃、森誠司、高田義一、山本浩文
- Organizer
  第64回日本生化学会近畿支部例会
- Data Source
  KAKENHI-PROJECT-17K08775
[Presentation] 免疫チェックポイント抗体治療の経験と今後の展望2017
- Author(s)
  武田力、武田和、田中千栄里、久保田結衣、大木明子、武田寛子、服部宣明、横山雄起、山本浩文
- Organizer
  第30回　日本バイオセラピィ学会
- Data Source
  KAKENHI-PROJECT-17K10548
[Presentation] super carbonate apatiteを使用したICG光線力学療法の検討2017
- Author(s)
  玉井皓己、高橋秀和、原口直紹、太田みのり、西村潤一、畑泰司、松田宙、水島恒和、土岐祐一郎、森正樹、山本浩文
- Organizer
  第117回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-15H04920
[Presentation] Epigenetic alterations by microRNAs in carcinogenesis of colorectal cancer2016
- Author(s)
  Tsuyoshi Hata, Hirofumi Yamamoto, Daisuke Okuzaki, Hisataka Ogawa, Konno Msamitsu, Hidekazu Takahashi, Naoaki Haraguchi, Junichi Nishimura, Taishi Hata, Ichiro Takemasa, Taro Sato, Tsunekazu Mizushima, Hideshi Ishii, Yuichiro Doki, Masaki Mori
- Organizer
  69th Annual Cancer Symposium of the Society of Surgical Oncology (SSO 2016)
- Place of Presentation
  米国, マサチューセッツ州, ボストン
- Year and Date
  2016-03-03
- Data Source
  KAKENHI-PROJECT-26670605
[Presentation] 卓越したin vivo腫瘍デリバリーを達成する新規DDSのメカニズム解析2016
- Author(s)
  Hirofumi Yamamoto
- Organizer
  第75回日本癌学会学術集会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-10-06
- Invited
- Data Source
  KAKENHI-PROJECT-15H04920
[Presentation] Super carbonate apatite as simplified systemic nanoparticle carrier.2014
- Author(s)
  Hirofumi Yamamoto, Xin Wu, Susumu Miyazaki, Mamoru Uemura, Taishi Hata, Junichi Nishimura, Ichiro Takemasa, Tsunekazu Mizushima, Yuichiro Doki, Masaki Mori
- Organizer
  AACR annual meeting
- Place of Presentation
  San Diego
- Year and Date
  2014-05-03
- Data Source
  KAKENHI-PROJECT-24390315
[Presentation] シンポジウム 3　「大腸癌治療におけるバイオマーカー」microRNAによる大腸癌の診断と治療への取組み2014
- Author(s)
  山本浩文、森正樹
- Organizer
  第69回日本大腸肛門病学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-07
- Data Source
  KAKENHI-PROJECT-24390315
[Presentation] リンパ節中の微小転移量はStage II 大腸癌の再発率を規定する2013
- Author(s)
  山本浩文　他
- Organizer
  第６８回日本消化器外科学会　シンポジウム１
- Place of Presentation
  宮崎
- Data Source
  KAKENHI-PROJECT-24390315
[Presentation] An Impact of Epigenetic Approaches Targeting JARID1B to Modulate Malignant Behaviors of Gastrointestinal Cancer (Minisymposium)2013
- Author(s)
  Ohta K., Kano Y., Konno M., Kagawa Y., Nishikawa S., Hasegawa S., Fukusumi T., Ogawa H., Hamabe A., Satoh T., Haraguchi N., Yamamoto H., Doki Y., Mori M., Ishii H.
- Organizer
  American Association for Cancer Research(AACR) Annual Meeting 2013
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-23591962
[Presentation] An Impact of Epigenetic Approaches Targeting JARID1B to Modulate Malignant Behaviors of Gastrointestinal Cancer2013
- Author(s)
  Kano Y., Konno M., Kagawa Y., Nishikawa S., Hasegawa S., Fukusumi T., Ogawa H., Hamabe A., Satoh T., Haraguchi N., Yamamoto H., Doki Y., Mori M., Ishii H.
- Organizer
  American Association for Cancer Research(AACR) Annual Meeting 2013
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-23591962
[Presentation] 食道癌におけるC4. 4A発現の意義2012
- Author(s)
  大塚正久、山本浩文、森正樹
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌ロイトン札幌(招待講演)
- Year and Date
  2012-09-21
- Data Source
  KAKENHI-PROJECT-24390315
[Presentation] 転移遺伝子C4. 4Aの細胞外基質構成因子への影響2012
- Author(s)
  大塚正久、山本浩文、森正樹
- Organizer
  第112回日本外科学会定期学術集会
- Place of Presentation
  千葉幕張メッセ(招待講演)
- Year and Date
  2012-04-14
- Data Source
  KAKENHI-PROJECT-24390315
[Presentation] C4. 4A IS a candidate prognostic marker of esophageal cancer by association with Tenascin-C2012
- Author(s)
  M Ohtsuka, H Yamamoto, M Mori
- Organizer
  Nlnth AACR-Japanese Cancer Association joint conference
- Place of Presentation
  Hawaii. Maui, Hyatt Regency laui(招待講演)
- Year and Date
  2012-02-23
- Data Source
  KAKENHI-PROJECT-24390315
[Presentation] 大腸癌における先進部C4. 4A発現とEMTとの関連2012
- Author(s)
  大塚正久、山本浩文、森正樹
- Organizer
  第16回日本がん分子標的治療学会
- Place of Presentation
  小倉西日本総合展示場(招待講演)
- Year and Date
  2012-06-28
- Data Source
  KAKENHI-PROJECT-24390315
[Presentation] 転移遺伝子C4. 4Aの細胞外基質構成因子への影響2012
- Author(s)
  大塚正久、山本浩文、森正樹
- Organizer
  第22回日本サイトメトリー学会学術集会
- Place of Presentation
  千里ライフサイエンスセンター(招待講演)
- Year and Date
  2012-06-30
- Data Source
  KAKENHI-PROJECT-24390315
[Presentation] Clinical application of molecular biological testing for detecting lymph node metastasis of colorectal cancer. 8th International Symposium on Minimal Residual Cancer2011
- Author(s)
  Hirofumi Yamamoto
- Organizer
  Evening Seminar
- Place of Presentation
  Osaka
- Year and Date
  2011-09-21
- Data Source
  KAKENHI-PROJECT-21390360
[Presentation] 大腸癌リンパ節転移検査における分子生物学的検査法の臨床への応用2011
- Author(s)
  山本浩文
- Organizer
  第100回日本病理学会総会ランチョンセミナー(招待講演)
- Place of Presentation
  横浜
- Year and Date
  2011-04-30
- Data Source
  KAKENHI-PROJECT-21390360
[Presentation] 大腸癌リンパ節転移検査における分子生物学的検査法の臨床への応用2011
- Author(s)
  山本浩文
- Organizer
  第100回日本病理学会総会ランチョンセミナー
- Place of Presentation
  横浜(招待講演)
- Year and Date
  2011-04-30
- Data Source
  KAKENHI-PROJECT-21390360
[Presentation] OSNA法を用いた新たな大腸癌リンパ節転移検査への可能性2011
- Author(s)
  山本浩文
- Organizer
  第66回日本消化器外科学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23591962
[Presentation] Clinical application of molecular biological testing for detecting lymph node metastasis of colorectal cancer2011
- Author(s)
  Hirofumi Yamamoto, et al
- Organizer
  8th International Symposium on Minimal Residual Cancer Evening Seminar
- Place of Presentation
  Osaka
- Year and Date
  2011-09-21
- Data Source
  KAKENHI-PROJECT-21390360
[Presentation] 癌と間質のinterfaceにおける分子解析と治療応用2009
- Author(s)
  山本浩文, 他
- Organizer
  第109回日本外科学会定期学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-20390357
[Presentation] 大腸癌網羅的遺伝子解析を用いた新規マーカー探索:余後関連遺伝子とそのタンパク発現2009
- Author(s)
  三宅正和、竹政伊知朗、渡辺真、池田正孝、山本浩文、水島恒和、関本貢嗣、松浦成昭、西村紀、土岐祐一郎、森正樹
- Organizer
  第109回日本外科学会期学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-20390357
[Presentation] 癌と間質のinterfaceにおける分子解析と治療応用2009
- Author(s)
  山本浩文、小西健、鈴木玲、原口直紹、水島恒和、竹政伊知朗、池田正孝、石井秀始、関本貢嗣、土岐祐一郎、森正樹
- Organizer
  第109回日本外科学会定期学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-20390357
[Presentation] NBS法を用いた網羅的タンパク解析による大腸癌関連マーカーの探索2009
- Author(s)
  三宅正和、竹政伊知朗、渡辺真、池田正孝、山本浩文、水島恒和、関本貢嗣、松浦成昭、西村紀、土岐祐一郎、森正樹
- Organizer
  第5回日本消化管学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20390357
[Presentation] NBS法による大腸癌組織を用いた新規肝転移関連蛋白の検討2009
- Author(s)
  徳岡優佳、竹政伊知朗、渡辺真、三宅正和、水島恒和、池田正孝、山本浩文、関本貢嗣、西村紀、門田守人、森正樹
- Organizer
  第109回日本外科学会定期学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-20390357
[Presentation] 生体内低酸素誘導遺伝子検索モデルとしての大腸癌肝転移巣の有用性2009
- Author(s)
  植村守、山本浩文、原口直紹、竹政伊知朗、水島恒和、池田正孝、石井秀始、関本貢嗣、土岐祐一郎、森正樹
- Organizer
  第20回日本消化器癌発生学会総会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-20390357
[Presentation] 皿管新生因子Adrenomedulmの大腸癌術後予後因子としての意義2008
- Author(s)
  植村守, 山本浩文, 田中純一, 竹政伊知朗, 池田正孝, 関本貢嗣, 門田守人
- Organizer
  第108回日本外科字会足期字術集会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-20390357
[Presentation] 大腸癌網m勺遺伝子解析を用いた新規マーカーを探索 : 高発現遺伝子とタンパク発現との比較2008
- Author(s)
  三宅正和, 竹政伊知朗, 池田正孝, 山本浩文, 関本貢嗣, 松原謙一, 門田守人
- Organizer
  第108回日本外科字会足期字術集会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-20390357
[Presentation] NBS法による大腸癌組織を用いた新規転移関連蛋白の検討2008
- Author(s)
  徳岡優佳, 竹政伊知朗, 渡辺真, 三宅正和, 人羅俊貴, 野村昌哉, 池田正孝, 山本浩文, 関本貢嗣, 西村紀, 門田守人
- Organizer
  第108回日本外科字会足期字術集会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-20390357
[Presentation] 大腸癌網羅的遺伝子解析を用いた新規マーカーを探索:高発現遺伝子とタンパク発現との比較2008
- Author(s)
  三宅正和、竹政伊知朗、池田正孝、山本浩文、関本貢嗣、松原謙一、門田守人
- Organizer
  第108回日本外科学会定期学術集会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-20390357
[Presentation] Identificaion of clon cancer-initiating cell.2008
- Author(s)
  Ishii H.,Haraguchi N., Tanaka F., Mimori K., Inoue H., Takemasa I., Ikda M., Yamamoto H.,ekimoto M.
- Organizer
  21st the Naito conference.
- Place of Presentation
  湘南
- Data Source
  KAKENHI-PROJECT-20390357
[Presentation] Identification of colon cancer-imtiatmg cells2008
- Author(s)
  Ishii H., Haraguchi N., Tanaka F., Mimori K., Inoue H., Takemasa I., Ikeda M., Yamamoto H., Sekimoto M., Mori M.
- Organizer
  21st the Naito conference
- Place of Presentation
  Shonan
- Data Source
  KAKENHI-PROJECT-20390357
[Presentation] 血管新生因子Adrenomedulinの大腸癌術後予後因子としての意義2008
- Author(s)
  植村守、山本浩文、田中純一、竹政伊知朗、池田正孝、関本貢嗣、門田守人
- Organizer
  第108回日本外科学会定期学術集会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-20390357
[Presentation] NBS法による大腸癌組織を用いた新規転移関連蛋白の検討2008
- Author(s)
  徳岡優佳、竹政伊知朗、渡辺真、三宅正和、人羅俊貴、野村昌哉、池田正孝、山本浩文、関本貢嗣、西村紀、門田守人
- Organizer
  第108回日本外科学会定期学術集会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-20390357

1. 横山雄起 (60615714)

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# of Collaborated Products: 4 results
2. SEKIMOTO Mitugu (10273658)

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Yamamoto Hirofumi 山本 浩文

YAMAMOTO Hirofumi 山本 浩文

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多分子標的型核酸と高性能化DDSによって転移性癌をリセットするムーンショット計画Principal Investigator

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シングルセル解析が紐解く老化細胞と癌幹細胞の治療抵抗性メカニズムPrincipal Investigator

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Yamamoto Hirofumi 山本浩文

YAMAMOTO Hirofumi 山本浩文