Mizushima Tsunekazu 水島恒和

… Alternative Names

MIZUSHIMA Tunekazu 水島恒和

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Researcher Number	00527707
Other IDs
Affiliation (Current)	2025: 大阪大学, 大学院医学系研究科, 招へい教授 2025: 獨協医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2023: 大阪大学, 大学院医学系研究科, 招へい教授 2022: 大阪大学, 大学院医学系研究科, 特任教授 2021: 大阪大学, 医学系研究科, 特任教授 2016 – 2020: 大阪大学, 医学系研究科, 寄附講座教授 2014 – 2015: 大阪大学, 医学(系)研究科(研究院), 寄付講座教授 … More 2014 – 2015: 大阪大学, 医学(系)研究科(研究院), 教授 2013: 大阪大学, 附属病院消化器外, 講師 2012 – 2013: 大阪大学, 医学(系)研究科(研究院), 講師 2012: 大阪大学, 医学系研究科, 講師 2011: 大阪大学, 医学(系)研究科(研究院), 助教 2011: 大阪大学, 医学系・研究科, 助教 2009 – 2011: 大阪大学, 医学系研究科, 助教 Less
Review Section/Research Field	Principal Investigator Digestive surgery / Basic Section 55020:Digestive surgery-related Except Principal Investigator Digestive surgery / Basic Section 55020:Digestive surgery-related / Basic Section 55010:General surgery and pediatric surgery-related / Basic Section 53010:Gastroenterology-related
Keywords	Principal Investigator 炎症性腸疾患 / 腸内細菌叢 / RNA sequence解析 / 腸管上皮細胞 / 小腸大腸肛門外科学 / 炎症性腸疾患関連癌 / 腸炎関連大腸癌 / 大腸癌 / 自然リンパ球 / 脂肪組織由来幹細胞 … More / 脂肪由来幹細胞 / クローン病 / 潰瘍性大腸炎 / 樹状細胞 / Th17細胞 / 免疫学 … More Except Principal Investigator 大腸癌 / 炎症性腸疾患 / 大腸がん / 自然リンパ球 / ex vivo / 間質 / 微小環境 / 腫瘍 / 培養細胞 / 悪性腫瘍 / がん / 癌 / がん遺伝子 / マイクロRNA / 免疫治療 / オートファジー / 低酸素 / プロテアソーム活性 / 治療抵抗性 / 低プロテアソーム活性 / 癌幹細胞 / 感受性診断 / 感受性性診断 / 次世代シーケンサー / 非侵襲性KRAS変異検査 / 薬剤感受性 / 癌の多様性 / 予後診断用臨床チップ / 個別化医療 / 予後予測 / 遺伝子発現プロファイル / パスウェイ / 臨床応用 / 予測診断 / 予後・治療応答性 / 潰瘍性大腸炎 / クローン病 / 炭酸ガス / 二酸化炭素送気法 / 消化器内視鏡 / 消化管 Less

炎症性発癌における自然リンパ球の役割解明
- Principal Investigator
  
  荻野崇之
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Osaka University
Elucidation of Epithelial Dysfunction in Response to Intestinal Microbiota in Inflammatory Bowel DiseasesPrincipal Investigator
- Principal Investigator
  
  水島恒和
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Osaka University
Reconstruction and the analysis of tumor stroma using ex vivo tumor model
- Principal Investigator
  
  Miyoshi NorikatNorikatsu
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Osaka University
Development of miRNA-based immunotherapy in cancer
- Principal Investigator
  
  Naohiro Nishida
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Osaka University
Biological Features of Inflammatory Bowel Disease-Associated Colorectal Cancer and the Association of Innate Lymphoid CellsPrincipal Investigator
- Principal Investigator
  
  Mizushima Tsunekazu
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Osaka University
The effects of Atg5-independent autophagy activator on DSS-induced colitis in mice
- Principal Investigator
  
  Matsuda Chu
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Osaka University
Proteasome activity and autophagy which relate to cancer stemness and treatment resistance
- Principal Investigator
  
  Uemura Mamoru
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  National Hospital Organization Osaka National Hospital Institute for Clinical Reserch
Feasibility and efficacy of autologous adipose-derived stem cell therapy for inflammatory bowel disease patientsPrincipal Investigator
- Principal Investigator
  
  Mizushima Tsunekazu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Osaka University
A novel noninvasive screening assay for RAS mutations in the peripheral blood sample using next-generation sequencing for anti-EGFR antibodies therapy
- Principal Investigator
  
  Takemasa Ichiro
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Sapporo Medical University
  Osaka University
Clinical application of gene expression signature as a predictor of recurrence in colorectal cancer
- Principal Investigator
  
  TAKEMASA Ichiro
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Osaka University
Resarch for the mechanisms of induction and differentiation of mucosal immune cells in the patients with inflammatory bowel diseasesPrincipal Investigator
- Principal Investigator
  
  MIZUSHIMA Tsunekazu
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Osaka University
Carbon dioxide insufflating endoscopy for patients with inflammatory bowel diseases : safety and efficacy study
- Principal Investigator
  
  NAKAJIMA Kiyokazu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Osaka University

All 2020 2019 2018 2017 2016 2015 2013 2012 2011 2010

All Journal Article Presentation

[Journal Article] Human NKp44+ ILC3 character associated with induction of tumor-associated tertiary lymphoid structures is altered in T3/T4 colorectal cancer.2020
- Author(s)
  Ikeda A, Ogino T, Kayama H, Okuzaki D, Nishimura J, Fujino S, Miyoshi N, Takahashi H, Uemura M, Matsuda C, Yamamoto H, Takeda K, Mizushima T, Mori M, Doki Y
- Journal Title
  
  Cancer Immunol. Res
  
  Volume: in press Issue: 6 Pages: 724-731
- DOI
  10.1158/2326-6066.cir-19-0775
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H04028, KAKENHI-PROJECT-17K10631, KAKENHI-PROJECT-20K09056
[Journal Article] Involvement of MAF1 homolog, negative regulator of RNA polymerase III in colorectal cancer progression.2019
- Author(s)
  Hokonohara K, Nishida N, Miyoshi N, Takahashi H, Haraguchi N, Hata T, Matsuda C, Mizushima T, Doki Y, Mori M.
- Journal Title
  
  International Journal of Oncology
  
  Volume: 54 Pages: 1001-1009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07970
[Journal Article] Disruption of Endolysosomal RAB5/7 Efficiently Eliminates Colorectal Cancer Stem Cells.2019
- Author(s)
  Takeda M, Koseki J, Takahashi H, Miyoshi N, Nishida N, Nishimura J, Hata T, Matsuda C, Mizushima T, Yamamoto H, Ishii H, Doki Y, Mori M, Haraguchi N.
- Journal Title
  
  Cancer Res
  
  Volume: 79 Pages: 1426-1437
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07970
[Journal Article] Sanguisorba officinalis L. derived from herbal medicine prevents intestinal inflammation by inducing autophagy in macrophages2019
- Author(s)
  Asuka Yasueda, Hisako Kayama, Michiko Murohashi, Junichi Nishimura, Koji Wakame, Ken-ichi Komatsu, Takayuki Ogino, Norikatsu Miyoshi, Hidekazu Takahashi, Mamoru Uemura, Chu Matsuda, Toru Kitagawa, Kiyoshi Takeda, Toshinori Ito, Yuichiro Doki, Hidetoshi Eguchi, Shigeomi Shimizu and Tsunekazu Mizushima,
- Journal Title
  
  Scientific Reports
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10632
[Journal Article] Laparoscopic surgery using a Gigli wire saw for locally recurrent rectal cancer with concomitant intraperitoneal sacrectomy2018
- Author(s)
  Uemura Mamoru、Ikeda Masataka、Kawai Kenji、Nishimura Junichi、Takemasa Ichiro、Mizushima Tsunekazu、Yamamoto Hirofumi、Sekimoto Mitsugu、Doki Yuichiro、Mori Masaki
- Journal Title
  
  Asian Journal of Endoscopic Surgery
  
  Volume: 11 Issue: 1 Pages: 83-86
- DOI
  10.1111/ases.12407
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10140
[Journal Article] Downregulation of serum metabolite GTA-446 as a novel potential marker for early detection of colorectal cancer2017
- Author(s)
  Hata T, Takemasa I, Takahashi H, Haraguchi N, Nishimura J, Hata T, Mizushima T, Doki Y, Mori M
- Journal Title
  
  J Cancer
  
  Volume: 117 Issue: 2 Pages: 227-232
- DOI
  10.1038/bjc.2017.163
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462013
[Journal Article] Adipose-Derived Stem Cells Ameliorate Experimental Murine Colitis via TSP-1-Dependent Activation of Latent TGF-β2017
- Author(s)
  Takeyama Hiroshi、Mizushima Tsunekazu、Uemura Mamoru、Haraguchi Naotsugu、Nishimura Junichi、Hata Taishi、Matsuda Chu、Takemasa Ichiro、Ikenaga Masakazu、Murata Kohei、Yamamoto Hirofumi、Doki Yuichiro、Mori Masaki
- Journal Title
  
  Digestive Diseases and Sciences
  
  Volume: 62 Issue: 8 Pages: 1963-1974
- DOI
  10.1007/s10620-017-4578-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10140
[Journal Article] Single-incision laparoscopic surgery for stricturing and penetrating Crohn's disease.2016
- Author(s)
  Mizushima T, Nakajima K, Takeyama H, Naito A, Osawa H, Uemura M, et al.
- Journal Title
  
  Single-incision laparoscopic surgery for stricturing and penetrating Crohn's disease.
  
  Volume: 46(2) Issue: 2 Pages: 203-8
- DOI
  10.1007/s00595-015-1145-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10140
[Journal Article] Long-term outcome of adrenalectomy for metastasis resulting from colorectal cancer with other metastatic sites: A report of 3 cases.2016
- Author(s)
  Uemura M, Kim HM, Ikeda M, Nishimura J, Hata T, Takemasa I, Mizushima T, Yamamoto H, Doki Y, Mori M.
- Journal Title
  
  Oncol Lett
  
  Volume: 12(3) Issue: 3 Pages: 1649-1654
- DOI
  10.3892/ol.2016.4897
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10140
[Journal Article] Down-Regulation of microRNA-132 is Associated with Poor Prognosis of Colorectal Cancer.2016
- Author(s)
  Mokutani Y, Uemura M, Munakata K, Okuzaki D, Haraguchi N, Takahashi H, Nishimura J, Hata T, Murata K, Takemasa I, Mizushima T, Doki Y, Mori M, Yamamoto H.
- Journal Title
  
  Ann Surg Oncol
  
  Volume: 23 (5) Issue: S5 Pages: 599-608
- DOI
  10.1245/s10434-016-5133-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10140
[Journal Article] Cancer stem-like properties in colorectal cancer cells with low proteasome activity.2016
- Author(s)
  Munakata K, Uemura M, Tanaka S, Kawai K, Kitahara T, Miyo M, Kano Y, Nishikawa S, Fukusumi T, Takahashi Y, Hata T, Nishimura J, Takemasa I, Mizushima T, Ikenaga M, Kato T, Murata K, Carethers JM, Yamamoto H, Doki Y, Mori M.
- Journal Title
  
  Clinical Cancer Research
  
  Volume: 22 Issue: 21 Pages: 5277-5286
- DOI
  10.1158/1078-0432.ccr-15-1945
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-15H01484, KAKENHI-PROJECT-16H02670, KAKENHI-PROJECT-15K15491, KAKENHI-PROJECT-15K10140
[Journal Article] (18)F-Fluorodeoxyglucose positron emission tomography ((18)F-FDG PET) for the early detection of response to neoadjuvant chemotherapy for locally advanced rectal cancer.2016
- Author(s)
  Nishimura J, Hasegawa J, Ogawa Y, Miwa H, Uemura M, Haraguchi N, Hata T, Yamamoto H, Takemasa I, Mizushima T, Nezu R, Doki Y, Mori M.
- Journal Title
  
  Surg Today
  
  Volume: 46(10) Issue: 10 Pages: 1152-1158
- DOI
  10.1007/s00595-015-1297-x
- Data Source
  KAKENHI-PROJECT-15K10140
[Journal Article] Fructose-bisphosphate aldolase A is a key regulator of hypoxic adaptation in colorectal cancer cells and involved in treatment resistance and poor prognosis.2016
- Author(s)
  Kawai K, Uemura M, Munakata K, Takahashi H, Haraguchi N, Nishimura J, Hata T, Matsuda C, Ikenaga M, Murata K, Mizushima T, Yamamoto H, Doki Y, Mori M.
- Journal Title
  
  Int J Oncol
  
  Volume: 50 (2) Issue: 2 Pages: 525-534
- DOI
  10.3892/ijo.2016.3814
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10140
[Journal Article] 【消化管の再生医療】脂肪組織由来幹細胞を用いた消化管再生医療2016
- Author(s)
  水島恒和，深田唯史，土岐祐一郎，森　正樹
- Journal Title
  
  Med Sci Digest
  
  Volume: 42 Pages: 77-80
- Data Source
  KAKENHI-PROJECT-26462012
[Journal Article] First-line cetuximab-based chemotherapies for patients with advanced or metastatic KRAS wild-type colorectal cancer.2016
- Author(s)
  Uemura M, Kim HM, Hata T, Sakata K, Okuyama M, Takemoto H, Fujii H, Fukuzaki T, Morita T, Hata T, Takemasa I, Satoh T, Mizushima T, Doki Y, Mori M; Multi-Center Clinical Study Group of Osaka, Colorectal Cancer Treatment Group (MCSGO)..
- Journal Title
  
  Mol Clin Oncol
  
  Volume: 5(2) Issue: 2 Pages: 375-379
- DOI
  10.3892/mco.2016.938
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10140
[Journal Article] Platelet Activation Markers Are Associated with Crohn's Disease Activity in Patients with Low C-Reactive Protein.2015
- Author(s)
  Takeyama H, Mizushima T, Iijima H, Shinzaki S, Uemura M, et al.
- Journal Title
  
  Dig Dis Sci
  
  Volume: 60(11) Issue: 11 Pages: 3418-23
- DOI
  10.1007/s10620-015-3745-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10140
[Journal Article] A clinical trial of autologous adipose‑derived regenerative cell transplantation for a postoperative enterocutaneous fistula2015
- Author(s)
  Mizushima T
- Journal Title
  
  Surg Today
  
  Volume: In press Issue: 7 Pages: 835-842
- DOI
  10.1007/s00595-015-1246-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462012, KAKENHI-PROJECT-15H05791, KAKENHI-PROJECT-15K10140
[Journal Article] Characteristics of carbonic anhydrase 9 expressing cells in human intestinal crypt base2015
- Author(s)
  H Takahashi, et al.
- Journal Title
  
  International Journal of Oncology
  
  Volume: 48 Issue: 1 Pages: 115-122
- DOI
  10.3892/ijo.2015.3260
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19890, KAKENHI-PROJECT-15K10140
[Journal Article] Ephrin-A1 mRNA is associated with poor prognosis of colorectal cancer2013
- Author(s)
  Yamamoto H., Tei M., Uemura M., Takemasa I., Uemura Y., Murata K., Fukunaga M., Ohue M., Ohnishi T., Ikeda K., Kato T., Okamura S., Ikenaga M., Haraguchi N., Nishimura J., Mizushima T., Mimori K., Doki Y., Mori M.
- Journal Title
  
  Int J Oncol
  
  Pages: 549-555
- Data Source
  KAKENHI-PROJECT-23591962
[Journal Article] Depletion of JARID1B induces cellular senescence in human colorectal cancer2013
- Author(s)
  Ohta K., Haraguchi N., Kano Y., Kagawa Y., Konno M., Nishikawa S., Hamabe A., Hasegawa S., Ogawa H., Fukusumi T., Uemura M., Nishimura J., Hata T., Takemasa I., Mizushima T., Noguchi Y., Ozaki M., Kudo T., Sakai D., Satoh T., Fukami M., Ishii M., Yamamoto H., Doki Y., Mori M., Ishii H.
- Journal Title
  
  Int J Oncol
  
  Pages: 1212-1218
- Data Source
  KAKENHI-PROJECT-23591962
[Journal Article] Malignancy in Crohn's disease : Incidence and Clinical Characteristics in Japan2010
- Author(s)
  Mizushima T, Nakajima K, Ito T
- Journal Title
  
  Digestion
  
  Volume: 81 Pages: 265-270
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591486
[Journal Article] Functional analysis of agalactosyl IgG in inflammatory bowel disease patients.2010
- Author(s)
  Nakajima S, Mizushima T
- Journal Title
  
  Inflamm Bowel Dis
  
  Volume: (in Press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591486
[Presentation] Identification of novel EMT regulators in colorectal cancer2020
- Author(s)
  Naohiro Nishida, Satoshi Ishikawa, Daisuke Sakai, Toshifumi Yamaguchi, Shiki Fujino, Takayuki Ogino, Norikatsu Miyoshi, Hidekazu Takahashi, Mamoru Uemura, Tsunekazu Mizushima, Taroh Satoh, Masaki Mori, Hidetoshi Eguchi, Yuichiro Doki
- Organizer
  日本癌学会
- Data Source
  KAKENHI-PROJECT-18K07970
[Presentation] Autophagy induction of epithelium alleviate colitis in DSS model mice2019
- Author(s)
  Asuka Yasueda, Shigeomi Shimizu, Junichi Nishimura, Michiko Murohashi, Takayuki Ogino, Yoshifumi Watanabe, Koji Wakame, Kenichi Komatsu, Norikatsu Miyoshi, Hidekazu Takahashi ,Mamoru Uemura, Chu Matsuda, Tsunekazu Mizushima, Masaki Mori, Yuichiro Doki,
- Organizer
  UEG WEEK 2019 Bercelona (Spain)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10632
[Presentation] オートファジー誘導物質による薬剤誘導性腸炎緩和効果の検討2019
- Author(s)
  安枝明日香, 荻野崇之, 清水重臣, 西村潤一, 室橋道子, 渡部嘉文, 三吉範克,高橋秀和, 原口直紹, 畑泰司, 松田宙, 水島恒和, 森正樹, 土岐祐一郎
- Organizer
  第56回日本消化器免疫学会総会
- Data Source
  KAKENHI-PROJECT-17K10632
[Presentation] 大腸癌における新規予後因子ALDOAの追加検討2017
- Author(s)
  河合賢二, 植村守, 高橋秀和, 原口直紹, 西村潤一, 畑泰司, 松田宙, 水島恒和, 山本浩文, 土岐祐一郎, 森正樹
- Organizer
  第117回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-15K10140
[Presentation] 大腸癌における新規予後因子ALDOAの検討2016
- Author(s)
  河合賢二, 植村守, 高橋秀和, 原口直紹, 西村潤一, 畑泰司, 松田宙, 水島恒和, 土岐祐一郎, 森正樹
- Organizer
  日本癌治療学会
- Place of Presentation
  横浜
- Year and Date
  2016-10-20
- Data Source
  KAKENHI-PROJECT-15K10140
[Presentation] 術後難治性皮膚瘻に対する自己脂肪組織由来間葉系前駆細胞移植術の臨床応用2016
- Author(s)
  水島恒和，土岐祐一郎，森　正樹
- Organizer
  第102回日本消化器病学会総会
- Place of Presentation
  東京都
- Year and Date
  2016-04-22
- Data Source
  KAKENHI-PROJECT-26462012
[Presentation] 大腸癌における新規予後因子ALDOAの検討2016
- Author(s)
  河合賢二, 植村守, 高橋秀和, 原口直紹, 西村潤一, 畑泰司, 竹政伊知朗, 水島恒和, 山本浩文, 土岐祐一郎, 森正樹
- Organizer
  日本外科学会
- Place of Presentation
  大阪
- Year and Date
  2016-04-14
- Data Source
  KAKENHI-PROJECT-15K10140
[Presentation] miR-132の大腸癌肝転移における発現と臨床的意義2016
- Author(s)
  杢谷友香子, 山本浩文, 浜部敦史, 植村守, 原口直紹, 高橋秀和, 西村潤一, 畑泰司, 竹政伊知朗, 水島恒和, 土岐祐一郎, 森正樹
- Organizer
  日本外科学会
- Place of Presentation
  大阪
- Year and Date
  2016-04-14
- Data Source
  KAKENHI-PROJECT-15K10140
[Presentation] 術後難治性皮膚瘻に対する自己脂肪組織由来間葉系前駆細胞移植術の臨床応用2016
- Author(s)
  水島恒和，竹政伊知朗，畑　泰司，西村潤一，原口直紹，高橋秀和，竹山廣志，内藤　敦，深田唯史，山本浩文，土岐祐一郎，森　正樹
- Organizer
  第116回日本外科学会定期学術集会
- Place of Presentation
  大阪市
- Year and Date
  2016-04-14
- Data Source
  KAKENHI-PROJECT-26462012
[Presentation] 大腸癌における予後因子ALDOAの機能に関する検討2016
- Author(s)
  河合賢二, 植村守, 高橋秀和, 原口直紹, 西村潤一, 畑泰司, 松田宙, 水島恒和, 土岐祐一郎, 森正樹
- Organizer
  大腸肛門病学会
- Place of Presentation
  三重
- Year and Date
  2016-11-18
- Data Source
  KAKENHI-PROJECT-15K10140
[Presentation] 術後難冶性皮膚瘻に対する自己脂肪組織由来間葉系前駆細胞移植療法の臨床応用2015
- Author(s)
  水島恒和
- Organizer
  第69回手術手技研究会
- Place of Presentation
  高崎市
- Year and Date
  2015-05-16
- Data Source
  KAKENHI-PROJECT-26462012
[Presentation] 大腸癌の予後に寄与するメチル化異常に関わる遺伝子の解析2015
- Author(s)
  松村多恵三森功士, 植村守, 西村潤一, 畑泰司, 竹政伊知朗, 水島恒和, 山本浩文, 土岐祐一郎, 森正樹
- Organizer
  日本分子腫瘍マーカー研究会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-07
- Data Source
  KAKENHI-PROJECT-15K10140
[Presentation] 大腸癌肝転移におけるmiR-132の発現と臨床的意義2015
- Author(s)
  杢谷友香子, 植村守, 宗方幸二, 原口直紹, 高橋秀和, 西村潤一, 畑泰司, 竹政伊知朗, 水島恒和, 山本浩文, 土岐祐一郎, 森正樹
- Organizer
  日本癌治療学会
- Place of Presentation
  京都
- Year and Date
  2015-10-30
- Data Source
  KAKENHI-PROJECT-15K10140
[Presentation] ^proteasomeactivityandcancersternnessincolorectalcancer2015
- Author(s)
  MamoruUemura. KojiMunakata. JunichiNishimura, TaishiHata, Ichiro Takemasa, Tsunekazu Mizushima, HirofumiYamamoto, YuichiroDoki, MasakiMori.
- Organizer
  AACR annual meeting
- Place of Presentation
  Philadelphia
- Year and Date
  2015-04-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10140
[Presentation] 大腸癌先進部でのHexokinase 2とリン酸化型pyruvate dehydrogenase E1αの発現強度を複合解析することで予後不良群を鋭敏に予測できる2015
- Author(s)
  浜部敦史, 山本浩文, 今野雅允, 植村守, 西村潤一, 畑泰司, 竹政伊知朗, 水島恒和, 西田尚弘, 川本弘一, 小関準, 土岐祐一郎, 森正樹, 石井秀始
- Organizer
  日本分子腫瘍マーカー研究会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-07
- Data Source
  KAKENHI-PROJECT-15K10140
[Presentation] microRNA-4689によるKRASとAKTの多分子制御が、KRAS変異型大腸癌に対する新規治療法と成り得る2015
- Author(s)
  平木将之, 西村潤一, 高橋秀和, 呉しん, 高橋佑典, 西田尚弘, 植村守, 畑泰司, 竹政伊知朗, 水島恒和, 土岐祐一郎, 森正樹, 山本浩文
- Organizer
  日本分子腫瘍マーカー研究会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-07
- Data Source
  KAKENHI-PROJECT-15K10140
[Presentation] 大腸癌皮下腫瘍モデルにおける、microRNAを用いた癌リプログラミング療法の有用性の検討2015
- Author(s)
  小川久貴, 呉シン, 今野雅充, 西田尚弘, 川本弘一, 野田幸蔵, 植村守, 西村潤一, 畑泰司, 竹政伊知朗, 水島恒和, 山本浩文, 土岐祐一郎, 森正樹, 石井秀始
- Organizer
  日本分子腫瘍マーカー研究会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-07
- Data Source
  KAKENHI-PROJECT-15K10140
[Presentation] 大腸癌における低プロテアソーム活性細胞の治療抵抗性に対するメカニズムの検討2015
- Author(s)
  宗方幸二, 植村守, 西村潤一, 畑泰司, 竹政伊知朗, 水島恒和, 山本浩文, 土岐祐一郎, 森正樹
- Organizer
  日本分子腫瘍マーカー研究会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-07
- Data Source
  KAKENHI-PROJECT-15K10140
[Presentation] クローン病の手術症例における腸管不全(短腸症候群)の実態-多施設共同研究2012
- Author(s)
  渡辺和宏、佐々木巖、福島浩平、舟山裕士、杉田昭、二見喜太郎、池内浩基、根津理一郎、水島恒和、亀岡信悟、楠正人、吉岡和彦、畠山勝義、藤井久男、渡邉聡明、渡邊昌彦、渡辺守
- Organizer
  第112回日本外科学会定期学術集会
- Place of Presentation
  千葉
- Year and Date
  2012-04-14
- Data Source
  KAKENHI-PROJECT-22591486
[Presentation] PS-077-7 クローン病に対する直腸切断術術後の感染性合併症対策の意義2012
- Author(s)
  廣田昌紀、根津理一郎、中島清一、水島恒和、松並展輝、三方彰喜、清水潤三、金〓国、森島宏隆、相馬大人、金浩敏、杢谷友香子、大澤日出樹、荒木麻利子、松浦雄祐、三宅祐一郎、高畠弘幸、長谷川順一
- Organizer
  第112回日本外科学会定期学術集会
- Place of Presentation
  千葉
- Year and Date
  2012-04-14
- Data Source
  KAKENHI-PROJECT-22591486
[Presentation] PS-078-2 Crohn 病における活動性と凝固線溶系マーカーの検討2012
- Author(s)
  竹山廣志、水島恒和、関本貢嗣、山本浩文、池田正孝、中島清一、竹政伊知朗、西村潤一、土岐祐一郎、森正樹
- Organizer
  第112回日本外科学会定期学術集会
- Place of Presentation
  千葉
- Year and Date
  2012-04-14
- Data Source
  KAKENHI-PROJECT-22591486
[Presentation] A case of Crohn's colitis-associated rectal cancer following after sporadic adenocarcinoma in adenoma2012
- Author(s)
  Takeyama H. Mizushima T., Nakajima K., Takahashi H., Nishimura J., Takemasa I., Ikeda M., Yamamoto H., Sekimoto M., Nezu R., Ito T., Doki Y., Mori M
- Organizer
  6th Korea-Japan IBD Symposium
- Place of Presentation
  Tokyo
- Year and Date
  2012-01-28
- Data Source
  KAKENHI-PROJECT-22591486
[Presentation] PS-077-8 当院におけるクローン病症例に対する麻酔下肛門周囲検査の現状2012
- Author(s)
  水島恒和、中島清一、関本貢嗣、山本浩文、池田正孝、竹政伊知朗、西村潤一、根津理一郎、伊藤壽記、土岐祐一郎、森正樹
- Organizer
  第112回日本外科学会定期学術集会
- Place of Presentation
  千葉
- Year and Date
  2012-04-14
- Data Source
  KAKENHI-PROJECT-22591486
[Presentation] PO-5-5 クローン病診療における外科の役割、2012
- Author(s)
  水島恒和、中島清一、関本貢嗣、山本浩文、池田正孝、竹政伊知朗、西村潤一、根津理一郎、土岐祐一郎、森正樹
- Organizer
  第67回日本消化器外科学会総会
- Place of Presentation
  富山
- Year and Date
  2012-07-20
- Data Source
  KAKENHI-PROJECT-22591486
[Presentation] 炎症性腸疾患に対する用手補助腹腔鏡下手術の意義2011
- Author(s)
  中島清一、根津理一郎、廣田昌紀、水島恒和、関本貢嗣、伊藤壽記、土岐祐一郎、森正樹
- Organizer
  第111回日本外科学会
- Place of Presentation
  紙上開催
- Year and Date
  2011-05-28
- Data Source
  KAKENHI-PROJECT-22591486
[Presentation] クローン病に対する直腸切断術時の術後感染性合併症対策2011
- Author(s)
  廣田昌紀、根津理一郎、中島清一、水島恒和、松並展輝、三方彰喜、森島宏隆、金〓国、西村潤一、相馬大人、長谷川順一
- Organizer
  第111回日本外科学会
- Place of Presentation
  紙上開催
- Year and Date
  2011-05-28
- Data Source
  KAKENHI-PROJECT-22591486
[Presentation] Crohn's colitis に対する minimally invasive extensive colectomy の意義2011
- Author(s)
  中島清一、根津理一郎、廣田昌紀、水島恒和、関本貢嗣、土岐祐一郎、森正樹
- Organizer
  第66回大腸肛門病学会
- Place of Presentation
  東京
- Year and Date
  2011-11-26
- Data Source
  KAKENHI-PROJECT-22591486
[Presentation] クローン病に対するminimally invasive extensive colectomy の治療成績2011
- Author(s)
  中島清一、根津理一郎、廣田昌紀、水島恒和、関本貢嗣、伊藤壽記、土岐祐一郎、森正樹
- Organizer
  第66回日本消化器外科学会
- Place of Presentation
  名古屋
- Year and Date
  2011-07-15
- Data Source
  KAKENHI-PROJECT-22591486
[Presentation] クローン病術後症例に対する合成 Xa 阻害薬の使用経験2011
- Author(s)
  水島恒和、池田正孝、中島清一、西村潤一、竹政伊知朗、甲斐康之、山本浩文、関本貢嗣、土岐祐一郎、森正樹
- Organizer
  第66回日本消化器外科学会
- Place of Presentation
  名古屋
- Year and Date
  2011-07-15
- Data Source
  KAKENHI-PROJECT-22591486
[Presentation] Mori M. Malignancy in Crohn's disease:The incidence and clinical characteristics in Japan2010
- Author(s)
  Mizushima T. Nakajima K., Kai Y., Yamamoto H., Ikeda M., Takemasa I., Sekimoto M., Nezu R., Ito T., Doki Y.
- Organizer
  XXIV ISUCRUS Biennial Congress
- Place of Presentation
  Seoul
- Year and Date
  2010-03-23
- Data Source
  KAKENHI-PROJECT-22591486
[Presentation] Bcl-2 retards the development of chronic colitis in interleukin-10 gene-deficient mice2010
- Author(s)
  Takahashi H. Mizushima T., Ito T., Kai Y., Takemasa I., Ikeda M., Yamamoto H., Sekimoto M., Doki Y., Mori M
- Organizer
  XXIV ISUCRUS Biennial Congress
- Place of Presentation
  Seoul
- Year and Date
  2010-03-23
- Data Source
  KAKENHI-PROJECT-22591486
[Presentation] 潰瘍性大腸炎に対する低侵襲手術の標準化-learning curve の解析を通じて2010
- Author(s)
  中島清一、根津理一郎、廣田昌紀、西村潤一、甲斐康之、水島恒和、関本貢嗣、伊藤壽紀、土岐祐一郎、森正樹
- Organizer
  第110回日本外科学会定期学術集会
- Place of Presentation
  名古屋
- Year and Date
  2010-04-10
- Data Source
  KAKENHI-PROJECT-22591486
[Presentation] Minimally invasive surgery for IBD: an update2010
- Author(s)
  Nakajima K. Hirota M., Mizushima T
- Organizer
  Japan-Korea IBD Symposium
- Place of Presentation
  Seoul
- Year and Date
  2010-10-02
- Data Source
  KAKENHI-PROJECT-22591486
[Presentation] クローン病長期 HPN 症例の検討2010
- Author(s)
  水島恒和、中島清一、甲斐康之、玉川浩司、松田宙、山本浩文、池田正孝、竹政伊知朗、原口直紹、関本貢嗣、井上善文、根津理一郎、伊藤壽記、土岐祐一郎、森正樹
- Organizer
  第96回日本消化器病学会総会
- Place of Presentation
  新潟
- Year and Date
  2010-04-24
- Data Source
  KAKENHI-PROJECT-22591486

1. NAKAJIMA Kiyokazu (30432537)

# of Collaborated Projects: 2 results

# of Collaborated Products: 16 results
2. TAKEMASA Ichiro (50379252)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
3. YAMAMOTO Hirofumi (30322184)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
4. Matsuda Chu (00379207)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
5. 西村潤一 (20379209)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
6. 関戸悠紀 (00781709)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 荻野崇之 (50597458)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. ITOU Yoshinori (20231152)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. TAKEDA Kiyoshi (20309446)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. IKEDA Masataka (80335356)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. SEKIMOTO Mithugu (10273658)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. Uemura Mamoru (10528483)

# of Collaborated Projects: 1 results

# of Collaborated Products: 21 results
13. Naohiro Nishida (50588118)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
14. Miyoshi NorikatNorikatsu (20528624)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 飯島英樹 (90444520)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 佐藤太郎 (40368303)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 畑泰司 (70644912)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
18. 河合賢二 (10717599)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
19. 波多豪 (80749747)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
20. 清水重臣 (70271020)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
21. 土岐祐一郎 (20291445)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 江口英利 (90542118)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 吉原輝一 (70850311)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 長谷川誠 (10966534)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 宮崎葉月 (10912438)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 伊藤寿記

# of Collaborated Projects: 0 results

# of Collaborated Products: 9 results
27. 田中真二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Mizushima Tsunekazu 水島 恒和

MIZUSHIMA Tunekazu 水島 恒和

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Elucidation of Epithelial Dysfunction in Response to Intestinal Microbiota in Inflammatory Bowel DiseasesPrincipal Investigator

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Biological Features of Inflammatory Bowel Disease-Associated Colorectal Cancer and the Association of Innate Lymphoid CellsPrincipal Investigator

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Feasibility and efficacy of autologous adipose-derived stem cell therapy for inflammatory bowel disease patientsPrincipal Investigator

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Resarch for the mechanisms of induction and differentiation of mucosal immune cells in the patients with inflammatory bowel diseasesPrincipal Investigator

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[Journal Article] Human NKp44+ ILC3 character associated with induction of tumor-associated tertiary lymphoid structures is altered in T3/T4 colorectal cancer.2020

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[Journal Article] Involvement of MAF1 homolog, negative regulator of RNA polymerase III in colorectal cancer progression.2019

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[Journal Article] Disruption of Endolysosomal RAB5/7 Efficiently Eliminates Colorectal Cancer Stem Cells.2019

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Mizushima Tsunekazu 水島恒和

MIZUSHIMA Tunekazu 水島恒和

[Journal Article] 【消化管の再生医療】脂肪組織由来幹細胞を用いた消化管再生医療2016