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SHIMIZU Shigeomi  清水 重臣

Researcher Number 70271020
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-8437-0791
External Links
Affiliation (Current) 2021: 東京医科歯科大学, 難治疾患研究所, 教授
Affiliation (based on the past Project Information) *help 2006 – 2020: Tokyo Medical and Dental University, Medical Research Institute, Professor, 難治疾患研究所, 教授
1999 – 2005: Osaka University Graduate School of Medicine, Assistant Professor, 医学系研究科, 助教授
2002: 大阪大学, 医学研究科, 助教授
1996 – 1998: Osaka University Medical School, Assistant Professor, 医学部, 助手
Review Section/Research Field
Principal Investigator
Biological Sciences / Pathological medical chemistry / Complex systems / Functional biochemistry / General medical chemistry / Digestive surgery / Cell biology / Pathological medical chemistry / Medium-sized Section 44:Biology at cellular to organismal levels, and related fields
Except Principal Investigator
General surgery … More / Digestive surgery / Biological Sciences / General surgery / Thoracic surgery / Molecular biology / Digestive surgery / 細胞死(アポトーシス) Less
Keywords
Principal Investigator
ミトコンドリア / アポトーシス / Bcl-2 / オートファジー / 神経変性疾患 / Atg5 / Bax / ゴルジ体 / シグナル伝達 / 生体分子 … More / ストレス / 発癌 / ネクローシス / 細胞生物 / Omi / 遺伝学 / 貧血 / 低分子化合物 / 電子顕微鏡 / 生体膜 / Atg5非依存性 / Atg5非依存的オートファジー / 癌 / Ulk1 / Bak / ケミカルバイオロジー / apoptosis / mitochondria / VDAC / Tat-BH4 / ATG5 / 新規オートファジー / 細胞・組織 / オルガネラ / ゾーン / 小胞体 / Bid / Bik / シトクロムC / 膜透過性亢進 / 放射線 / サイクロフィリンD / 膜透過性亢進現象 / mnd2 / パーキンソン病 / サイクロフィリン / permeability transition / カスペース / Smac / Bc1-2 / 蛋白質スプライシング / alternative macroautohagy / 膜透過性 / BH3 / がん / 発生 / alternative macroautophagy / オートファジー病 / 細胞リモデリング / 血液疾患 / 細胞情報伝達機構 / bax / bak / 細胞分化 / caspase-3(yama / cpp32) / yama / cpp32 / caspase-3(CPP32 / Yama) / シトクロムc / cytochrome c / BH4 / aptosis / 細胞死 / Beclin1 / autophagy / cell death / 神経変性 / 脳老化 / 脳老化変性タンパク質 / 実験病理学 / Atg5非依存的 / 認知症 / 神経科学 / 老化 / エンドソーム / 超解像顕微鏡 / GOMED / RIPK3 / 小胞輸送 … More
Except Principal Investigator
アポトーシス / ミトコンドリア / bcl-2 / Bcl-2 / apoptosis / オートファジー / ICE / mitochondria / p53 / VEGF / HIF-1 / hypoxia / アデノウイルスベクター / CTLA4-Ig / Fas Ligand / CTLA4Ig / FK506 / 炎症性腸疾患 / Th1 / 無酸素障害 / necrosis / CPP-32 / 核 / プログラム細胞死 / カスペース / シトクロムc / DNA傷害 / Acinus / Becline / APG5 / ナノバブル水 / 虚血再灌流傷害 / 心筋虚血 / 心筋保護 / 凍結保存 / Bc1-2 / caspase / dominant negative / 膵・膵島移植 / HVJリポソーム / Fas ligand / インスリン依存型糖尿病(IDDM) / BBラット / NKT細胞 / インスリン依存型糖尿病 / 膵島移植 / islet / BB-rat / IDDM / NKT cells / 膵島 / CTL4Ig / Islet / adenoviral vector / IL-10ノックアウトマウス / Bcl-2トランスジェニックマウス / 腸管上皮 / IL-10^<- / ->マウス / 消化管上皮 / Inflammatory Bowel Disease / IL-10 knock out mouse / Bcl transgenic mouse / Intestinal epithelium / 動脈硬化 / 平滑筋細胞 / Bcl-2ファミリー / PTP / Apoptosis / Atherosclerosis / Smooth muscle cell Less
  • Research Projects

    (38 results)
  • Research Products

    (240 results)
  • Co-Researchers

    (84 People)
  •  Novel role of Golgi apparatus for non-cell autonomous eventsPrincipal InvestigatorOngoing

    • Principal Investigator
      清水 重臣
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 44:Biology at cellular to organismal levels, and related fields
    • Research Institution
      Tokyo Medical and Dental University
  •  The effects of Atg5-independent autophagy activator on DSS-induced colitis in mice

    • Principal Investigator
      Matsuda Chu
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Osaka University
  •  Regulation of brain aging by alternative autophagyPrincipal Investigator

    • Principal Investigator
      清水 重臣
    • Project Period (FY)
      2017
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Medical and Dental University
  •  Analysis of "Response zone" and " Communication zone" in mitochondria and Golgi apparatusPrincipal InvestigatorOngoing

    • Principal Investigator
      清水 重臣
    • Project Period (FY)
      2017 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Medical and Dental University
  •  Toward an integrative understanding of functional zones in organellesArea Organizer

    • Area Organizer
      清水 重臣
    • Project Period (FY)
      2017 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
  •  Toward an integrative understanding of functional zones in organellesPrincipal InvestigatorOngoing

    • Principal Investigator
      清水 重臣
    • Project Period (FY)
      2017 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Medical and Dental University
  •  Biological roles of novel proteolytic mechanism GOMEDPrincipal Investigator

    • Principal Investigator
      shimizu shigeomi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      General medical chemistry
    • Research Institution
      Tokyo Medical and Dental University
  •  Development of small compounds that induce alternative autophagyPrincipal Investigator

    • Principal Investigator
      SHIMIZU Shigeomi
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Tokyo Medical and Dental University
  •  新規オートファジーによる脳老化タンパク質調節機構の解析と創薬開発研究Principal Investigator

    • Principal Investigator
      清水 重臣
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Medical and Dental University
  •  Development of autophagy visualization tools and analyses of physiological roles of autophagyPrincipal Investigator

    • Principal Investigator
      SHIMIZU Shigeomi
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      General medical chemistry
    • Research Institution
      Tokyo Medical and Dental University
  •  ミトコンドリア膜上に一過性に形成される過渡的細胞死孔の捕捉Principal Investigator

    • Principal Investigator
      清水 重臣
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      Tokyo Medical and Dental University
  •  Structural analysis of mitochondrial apoptotic porePrincipal Investigator

    • Principal Investigator
      SHIMIZU Shigeomi
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Functional biochemistry
    • Research Institution
      Tokyo Medical and Dental University
  •  新しく発見したオートファジー機構を介した蛋白質品質管理システムの解析Principal Investigator

    • Principal Investigator
      清水 重臣
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Medical and Dental University
  •  ミトコンドリア膜上に一過性に形成される過渡期細胞死孔の捕捉Principal Investigator

    • Principal Investigator
      清水 重臣
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      Tokyo Medical and Dental University
  •  Studies of alternative macroautophagy and its application for "Autophagic Diseases"Principal Investigator

    • Principal Investigator
      SHIMIZU Shigeomi
    • Project Period (FY)
      2010 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Tokyo Medical and Dental University
  •  新しく発見したオートファジーを基盤とした細胞内浄化システムの包括的理解Principal Investigator

    • Principal Investigator
      清水 重臣
    • Project Period (FY)
      2010
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Functional biochemistry
    • Research Institution
      Tokyo Medical and Dental University
  •  アポトーシスを可視化するマウスの開発とその応用Principal Investigator

    • Principal Investigator
      清水 重臣
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Tokyo Medical and Dental University
  •  酸素ナノバブル水の細胞機能保護効果の解明、特に心臓保存への応用に関する研究Principal Investigator

    • Principal Investigator
      清水 重臣, 田中 啓之
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Thoracic surgery
    • Research Institution
      Tokyo Medical and Dental University
  •  ミトコンドリアストレスを介した神経変性疾患の分子機構解明とその治療Principal Investigator

    • Principal Investigator
      清水 重臣
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Medical and Dental University
  •  ミトコンドリアストレスを介した神経変性疾患の分子機構解明とその治療Principal Investigator

    • Principal Investigator
      清水 重臣
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  発癌におけるオートファジー様細胞死の役割とそれを応用した分子標的治療法の開発

    • Principal Investigator
      長谷川 順一
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Osaka University
  •  Analysis of biological role and molecular mechanisms of autophagic cell deathPrincipal Investigator

    • Principal Investigator
      SHIMIZU Shigeomi
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Tokyo Medical and Dental University
      Osaka University
  •  ミトコンドリア膜透過性亢進機構を標的とした抗アポトーシス薬の開発Principal Investigator

    • Principal Investigator
      清水 重臣
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  Regulation of Intestinal Mucosal Immunity in a Mouse Model on Inflammatory Bowel Disease

    • Principal Investigator
      ITO Toshinori
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Osaka University
  •  Study of the molecular mechanism and clinical implication of a novel apoptosis gene

    • Principal Investigator
      YASUDA Osamu
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      細胞死(アポトーシス)
    • Research Institution
      Osaka University
  •  ミトコンドリア膜透過性亢進機構を標的とした抗アポトーシス薬の開発Principal Investigator

    • Principal Investigator
      清水 重臣
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  アポトーシスにおけるミトコンドリア膜透過性亢進因子の同定とその分子機構の解明Principal Investigator

    • Principal Investigator
      清水 重臣
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  Development of anti-and pro-apoptotic drugs via regulation of VDAC, a mitochondrial outermembrane proteinPrincipal Investigator

    • Principal Investigator
      SHIMIZU Shigeomi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Osaka University
  •  アポトーシスにおけるミトコンドリア膜透過性亢進因子の同定とその分子機構の解明Principal Investigator

    • Principal Investigator
      清水 重臣
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  Research for immuno-logical tolerance induction in islet xeno-transplantation -Therapeutic effect of a adenovirus or retrovirus mediated CTLA4Ig gene transfer combined with immunosuppressive regents-

    • Principal Investigator
      NAKATA Seizou
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Osaka University
  •  Identification of novel cytochrome c releasing factor and analysis of its molecular function on apoptosisPrincipal Investigator

    • Principal Investigator
      SHIMIZU Shigeomi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cell biology
    • Research Institution
      Osaka University
  •  アポトーシスにおける細胞質から核への情報伝達メカニズム

    • Principal Investigator
      辻本 賀英
    • Project Period (FY)
      1999 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  The induction of a donor-specific tolerance in islet xenotransplantation models by Bcl-2/Fas ligand transfection combined with immunosuppressive agents .

    • Principal Investigator
      NAKATA Seizou
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Osaka University
  •  Development of novel cancer gene therapy using HIF-1 gene

    • Principal Investigator
      YUMIBA Takeyoshi
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Osaka University
  •  Study of molecular basis of apoptosis using in vitro system

    • Principal Investigator
      TSUJIMONOTO Yoshihide
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      Molecular biology
    • Research Institution
      Osaka University
  •  Novel cancer gene therapy using apoptosis-related genePrincipal Investigator

    • Principal Investigator
      SHIMIZU Shigeomi
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Osaka University
  •  肝虚血障害機構の遺伝学的解明と細胞死抑制遺伝子bc1−2導入による保護

    • Principal Investigator
      上池 渉
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      Osaka University
  •  STUDY OF APOPTOSIS IN VITRO CELL-FREE SYSTEM

    • Principal Investigator
      TSUJIMOTO Yoshihide
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Osaka University Medical School

All 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book Patent

  • [Book] Innovative Medicine : Basic Research and Development2015

    • Author(s)
      shimizu S
    • Total Pages
      339
    • Publisher
      Springer Press
    • Data Source
      KAKENHI-PUBLICLY-15H01554
  • [Book] Innovative Medicine : Basic Research and Development2015

    • Author(s)
      Shimizu S
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-22229002
  • [Book] Innovative Medicine : Basic Research and Development2015

    • Author(s)
      Shimizu S
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-25670139
  • [Book] AUTOPHAGY: Cancer, Other Pathologies, Inflammation, Immunity, and Infection.Vol. 22014

    • Author(s)
      S. Shimizu, S. Arakawa, Y. Nishida, H. Yamaguchi, T. Yoshida.
    • Total Pages
      250
    • Publisher
      Academic Press,
    • Data Source
      KAKENHI-PROJECT-22229002
  • [Book] AUTOPHAGY: Cancer, Other Pathologies, Inflammation, Immunity, and Infection.Vol. 22014

    • Author(s)
      S. Shimizu, S. Arakawa, Y. Nishida, H. Yamaguchi, T. Yoshida.
    • Total Pages
      250
    • Publisher
      Academic Press,
    • Data Source
      KAKENHI-PUBLICLY-24121708
  • [Book] AUTOPHAGY: Cancer, Other Pathologies, Inflammation, Immunity, and Infection.Vol. 22014

    • Author(s)
      Shimizu S, Arakawa S, Nishida Y, Yamaguchi H, Yoshida T
    • Total Pages
      250
    • Publisher
      Academic Press
    • Data Source
      KAKENHI-PROJECT-25670139
  • [Book] アポトーシス調節系「分子標的薬」日本臨床2012

    • Author(s)
      清水重臣
    • Data Source
      KAKENHI-PROJECT-23657084
  • [Book] 細胞死解析プロトコール2011

    • Author(s)
      清水重臣
    • Total Pages
      223
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PUBLICLY-22020009
  • [Book] 細胞死解析プロトコール2011

    • Author(s)
      清水重臣
    • Total Pages
      223
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PUBLICLY-22121505
  • [Book] 細胞死解析プロトコール2011

    • Author(s)
      清水重臣
    • Total Pages
      223
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-23657084
  • [Book] 細胞死解析プロトコール2011

    • Author(s)
      清水重臣
    • Total Pages
      223
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-22229002
  • [Book] からだと酸素の事典2009

    • Author(s)
      清水重臣
    • Publisher
      朝倉書店(印刷中)
    • Data Source
      KAKENHI-PROJECT-19659349
  • [Book] 神経変性疾患のサイエンス2007

    • Author(s)
      清水重臣
    • Total Pages
      247
    • Publisher
      南山堂
    • Data Source
      KAKENHI-PROJECT-18023024
  • [Book] 細胞死・アポトーシス 集中マスター2005

    • Author(s)
      清水 重臣
    • Total Pages
      130
    • Publisher
      羊土社
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390094
  • [Book] Mammalian autophagy can occur through an Atg5/Atg7- independent pathway. AUTOPHAGY: Cancer, Other Pathologies

    • Author(s)
      S. Shimizu, S. Arakawa, Y. Nishida, H. Yamaguchi, T. Yoshida
    • Publisher
      Inflammation, Immunity, and Infection(印刷中)
    • Data Source
      KAKENHI-PROJECT-23657084
  • [Journal Article] Sanguisorba officinalis L. derived from herbal medicine prevents intestinal inflammation by inducing autophagy in macrophages2020

    • Author(s)
      4.Yasueda A, Kayama H, Murohashi M, Nishimura J, Wakame K, Komatsu K, Ogino T, Miyoshi N, Takahashi H, Uemura M, Matsuda C, Kitagawa T, Takeda K, Ito T, Doki Y, Eguchi H, Shimizu S, Mizushima T
    • Journal Title

      Scientific Reports

      Volume: press

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-17H06414
  • [Journal Article] Identification of a phosphorylation site on Ulk1 required for genotoxic stress-induced alternative autophagy2020

    • Author(s)
      Torii Satoru、Yamaguchi Hirofumi、Nakanishi Akira、Arakawa Satoko、Honda Shinya、Moriwaki Kenta、Nakano Hiroyasu、Shimizu Shigeomi
    • Journal Title

      Nature Communications

      Volume: 11

    • DOI

      10.1038/s41467-020-15577-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-17H06413, KAKENHI-PLANNED-17H06414, KAKENHI-PROJECT-17H01533, KAKENHI-PROJECT-17H04069
  • [Journal Article] The ceramide analogue N-(1-hydroxy-3-morpholino-1-phenylpropan-2-yl)decanamide induces large lipid droplet accumulation and highlights the effect of LAMP-2 deficiency on lipid droplet degradation2020

    • Author(s)
      Yuji Kato, Satoko Arakawa, Kazue Terasawa, Jin-Ichi Inokuchi, Takanori Iwata, Shigeomi Shimizu, Tetsuro Watabe, Miki Hara-Yokoyama
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters

      Volume: 30 Pages: 126891-126891

    • DOI

      10.1016/j.bmcl.2019.126891

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K12005, KAKENHI-ORGANIZER-17H06413, KAKENHI-PLANNED-17H06414, KAKENHI-PROJECT-17H01533
  • [Journal Article] Sanguisorba officinalis L. derived from herbal medicine prevents intestinal inflammation by inducing autophagy in macrophages.2020

    • Author(s)
      Yasueda A, Kayama H, Murohashi M, Nishimura J, Wakame K, Komatsu K, Ogino T, Miyoshi N, Takahashi H, Uemura M, Matsuda C, Kitagawa T, Takeda K, Ito T, Doki Y, Eguchi H, Shimizu S, Mizushima T
    • Journal Title

      Scientific Reports

      Volume: press

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-17H06413
  • [Journal Article] ER-resident sensor PERK is essential for mitochondrial thermogenesis in brown adipose tissue2020

    • Author(s)
      Kato H, Okabe K, Miyake M, Hattori K, Fukaya T, Tanimoto K, Beini S, Mizuguchi M, Torii S, Arakawa S, Ono M, Saito Y, Sugiyama T, Funatsu T, Sato K, Shimizu S, Oyadomari S, Ichijo H, Kadowaki H, Nishitoh H.
    • Journal Title

      Life Science Alliance

      Volume: 3

    • DOI

      10.26508/lsa.201900576

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06210, KAKENHI-PROJECT-18K06222, KAKENHI-PROJECT-19K08843, KAKENHI-PLANNED-15H05931, KAKENHI-ORGANIZER-17H06413, KAKENHI-PLANNED-17H06414, KAKENHI-PLANNED-17H06419, KAKENHI-PUBLICLY-18H04699, KAKENHI-PROJECT-17H01533, KAKENHI-PROJECT-18H02973, KAKENHI-PROJECT-19H02853, KAKENHI-PROJECT-17K09862, KAKENHI-PROJECT-18K06916, KAKENHI-PROJECT-18K19469
  • [Journal Article] Sanguisorba officinalis L. derived from herbal medicine prevents intestinal inflammation by inducing autophagy in macrophages.2020

    • Author(s)
      Yasueda A, Kayama H, Murohashi M, Nishimura J, Wakame K, Komatsu K, Ogino T, Miyoshi N, Takahashi H, Uemura M, Matsuda C, Kitagawa T, Takeda K, Ito T, Doki Y, Eguchi H, Shimizu S, Mizushima T
    • Journal Title

      Scientific reports

      Volume: press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H01533
  • [Journal Article] Characterization of monoclonal antibodies recognizing each extracellular loop domain of occludin2019

    • Author(s)
      Shimizu Yoshimi、Shirasago Yoshitaka、Suzuki Takeru、Hata Tomoyuki、Kondoh Masuo、Hanada Kentaro、Yagi Kiyohito、Fukasawa Masayoshi
    • Journal Title

      Journal of Biochemistry

      Volume: 166 Pages: 297-308

    • DOI

      10.1093/jb/mvz037

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-17H06413, KAKENHI-PLANNED-17H06417, KAKENHI-PROJECT-18H02856
  • [Journal Article] Prediction of intracellular targets of a small compound by analyzing peptides presented on MHC class I.2019

    • Author(s)
      Sugimoto Yuna、Murohashi Michiko、Arakawa Satoko、Honda Shinya、Shimizu Shigeomi
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 508 Pages: 480-486

    • DOI

      10.1016/j.bbrc.2018.11.089

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-17H06414, KAKENHI-PROJECT-17H01533, KAKENHI-PROJECT-17K15613
  • [Journal Article] Role of cyclooxygenase-2/prostaglandin E2/prostaglandin E receptor 4 signaling in cardiac reprogramming2019

    • Author(s)
      Muraoka Naoto、Nara Kaori、Tamura Fumiya、Kojima Hidenori、Yamakawa Hiroyuki、Sadahiro Taketaro、Miyamoto Kazutaka、Isomi Mari、Haginiwa Sho、Tani Hidenori、Kurotsu Shota、Osakabe Rina、Torii Satoru、Shimizu Shigeomi、Okano Hideyuki、Sugimoto Yukihiko、Fukuda Keiichi、Ieda Masaki
    • Journal Title

      Nature Communications

      Volume: 10 Pages: 1-15

    • DOI

      10.1038/s41467-019-08626-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06210, KAKENHI-PROJECT-18K08047, KAKENHI-PROJECT-18K08114, KAKENHI-PROJECT-17K16024, KAKENHI-PLANNED-17H06414, KAKENHI-PROJECT-17H01533, KAKENHI-PROJECT-17J06637, KAKENHI-PROJECT-18J21479, KAKENHI-PROJECT-15K09147, KAKENHI-PROJECT-16K19426, KAKENHI-PROJECT-19K22503, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05905, KAKENHI-PROJECT-17H03990
  • [Journal Article] Sanguisorba officinalis L. derived from herbal medicine prevents intestinal inflammation by inducing autophagy in macrophages2019

    • Author(s)
      Asuka Yasueda, Hisako Kayama, Michiko Murohashi, Junichi Nishimura, Koji Wakame, Ken-ichi Komatsu, Takayuki Ogino, Norikatsu Miyoshi, Hidekazu Takahashi, Mamoru Uemura, Chu Matsuda, Toru Kitagawa, Kiyoshi Takeda, Toshinori Ito, Yuichiro Doki, Hidetoshi Eguchi, Shigeomi Shimizu and Tsunekazu Mizushima,
    • Journal Title

      Scientific Reports

      Volume: -

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10632
  • [Journal Article] Beclin 1 regulates recycling endosome and is required for skin development in mice.2019

    • Author(s)
      Noguchi Saori、Honda Shinya、Saitoh Tatsuya、Matsumura Hiroyuki、Nishimura Emi、Akira Shizuo、Shimizu Shigeomi
    • Journal Title

      Commun Biol.

      Volume: 2 Pages: 37-37

    • DOI

      10.1038/s42003-018-0279-0

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18KK0229, KAKENHI-PUBLICLY-17H05614, KAKENHI-ORGANIZER-17H06413, KAKENHI-PLANNED-17H06414, KAKENHI-PLANNED-17H06415, KAKENHI-PROJECT-17H01533, KAKENHI-PROJECT-17K19514, KAKENHI-PROJECT-17K15613, KAKENHI-PROJECT-18H02637
  • [Journal Article] Ligand Binding to Human Prostaglandin E Receptor EP4 at the Lipid-Bilayer Interface2019

    • Author(s)
      Toyoda Y, Morimoto K, Suno R, et al.
    • Journal Title

      Nature chemical biology

      Volume: 15 Pages: 18-26

    • DOI

      10.1038/s41589-018-0131-3

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K05334, KAKENHI-PROJECT-18K14904, KAKENHI-PLANNED-15H05905, KAKENHI-PLANNED-17H06414, KAKENHI-PROJECT-17H01531, KAKENHI-PROJECT-17H03663, KAKENHI-PROJECT-17H03990, KAKENHI-PROJECT-19K22503, KAKENHI-PROJECT-19K16354, KAKENHI-ORGANIZER-15H05897, KAKENHI-PROJECT-19H00923
  • [Journal Article] Organelle zones in mitochondria2018

    • Author(s)
      Shimizu Shigeomi
    • Journal Title

      The Journal of Biochemistry

      Volume: 165 Pages: 101-107

    • DOI

      10.1093/jb/mvy068

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-17H06414, KAKENHI-PROJECT-17H01533
  • [Journal Article] Dram1 regulates DNA damage-induced alternative autophagy2018

    • Author(s)
      Nagata M, Arakawa S, Yamaguchi H, Torii S, Endo H, Tsujioka M, Honda S, Nishida Y, Konishi A, Shimizu S
    • Journal Title

      Cell stress

      Volume: 2 Pages: 55-65

    • DOI

      10.15698/cst2018.03.127

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08649, KAKENHI-PLANNED-17H06414, KAKENHI-PLANNED-26110005, KAKENHI-PROJECT-15K08420, KAKENHI-PROJECT-16K15230, KAKENHI-PROJECT-17K15448, KAKENHI-ORGANIZER-17H06413, KAKENHI-PROJECT-17H01533
  • [Journal Article] Biological Roles of Alternative Autophagy2018

    • Author(s)
      Shigeomi Shimizu
    • Journal Title

      Mol. Cells

      Volume: 41 Pages: 50-54

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-17H06414
  • [Journal Article] Association Between Autophagy and Neurodegenerative Diseases2018

    • Author(s)
      Nobuhiro Fujikake, Minkyoung Shin, Shigeomi Shimizu*
    • Journal Title

      Frontiers in Neuroscience

      Volume: 12 Pages: 255-255

    • DOI

      10.3389/fnins.2018.00255

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15360, KAKENHI-PLANNED-17H06414, KAKENHI-PROJECT-17H01533
  • [Journal Article] Biological Roles of Alternative Autophagy2018

    • Author(s)
      Shigeomi Shimizu
    • Journal Title

      Mol. Cells

      Volume: 41 Pages: 50-54

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-17H06413
  • [Journal Article] Small fluorescent molecules for monitoring autophagic flux2018

    • Author(s)
      Iwashita Hidefumi、Sakurai Hajime Tajima、Nagahora Noriyoshi、Ishiyama Munetaka、Shioji Kosei、Sasamoto Kazumi、Okuma Kentaro、Shimizu Shigeomi、Ueno Yuichiro
    • Journal Title

      FEBS Letters

      Volume: 592 Pages: 559-567

    • DOI

      10.1002/1873-3468.12979

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-17H06414, KAKENHI-ORGANIZER-17H06413, KAKENHI-PROJECT-17H01533
  • [Journal Article] Association between autophagy and neurodegenerative diseases2018

    • Author(s)
      Fujikake N, Shin M, Shimizu S
    • Journal Title

      Frontiers Neuroscience

      Volume: 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K15230
  • [Journal Article] Molecular mechanisms and physiological roles of Atg5/Atg7-independent alternative autophagy2017

    • Author(s)
      Arakawa S, Honda S, Yamaguchi H, Shimizu S.
    • Journal Title

      Proc. Jpn. Acad., Ser. B

      Volume: 93(6) Issue: 6 Pages: 378-385

    • DOI

      10.2183/pjab.93.023

    • NAID

      130005696809

    • ISSN
      0386-2208, 1349-2896
    • Language
      English
    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-17K15613, KAKENHI-PUBLICLY-17H05691, KAKENHI-PLANNED-26110005
  • [Journal Article] Identification of an atypical monocyte and committed progenitor involved in fibrosis.2017

    • Author(s)
      Kozaki T, Komano J, Kanbayashi D, Takahama M, Misawa T, Satoh T, Takeuchi O, Kawai T, Shimizu S, Matsuura Y, Akira S, Saitoh T
    • Journal Title

      PNAS

      Volume: 114 Pages: 96-101

    • DOI

      10.1073/pnas.1621508114

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PUBLICLY-15H01380, KAKENHI-PUBLICLY-15H01381, KAKENHI-PUBLICLY-15H01554, KAKENHI-PROJECT-16H06234, KAKENHI-PROJECT-26293107, KAKENHI-PROJECT-26713005, KAKENHI-PROJECT-26860453, KAKENHI-PROJECT-16K15230, KAKENHI-PROJECT-17K19559, KAKENHI-PUBLICLY-17H05691, KAKENHI-PROJECT-17H04066
  • [Journal Article] Role of Atg5-dependent cell death in the embryonic development of Bax/Bak double-knockout mice2017

    • Author(s)
      Arakawa S, Tsujioka M, Yoshida T, Tajima-Sakurai H, Nishida Y, Matsuoka Y, Yoshino I, Tsujimoto Y, Shimizu S.
    • Journal Title

      Cell Death & Differentiation

      Volume: 9 Pages: 1598-1608

    • DOI

      10.1038/cdd.2017.84

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PUBLICLY-17H05691, KAKENHI-PLANNED-17H06414, KAKENHI-PLANNED-26110005, KAKENHI-PROJECT-15K08420, KAKENHI-ORGANIZER-17H06413, KAKENHI-PROJECT-17H01533
  • [Journal Article] Rhodium-catalyzed odorless synthesis of diaryl sulfides from borylarenes and S-aryl thiosulfonates2017

    • Author(s)
      Kanemoto Kazuya、Sugimura Yasuyuki、Shimizu Shigeomi、Yoshida Suguru、Hosoya Takamitsu
    • Journal Title

      Chem. Commun.

      Volume: 53 Pages: 10640-10643

    • DOI

      10.1039/c7cc05868c

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-16H01133, KAKENHI-PROJECT-15H03118, KAKENHI-PROJECT-17H01533
  • [Journal Article] Intrinsic Autophagy Is Required for the Maintenance of Intestinal Stem Cells and for Irradiation-Induced Intestinal Regeneration.2017

    • Author(s)
      Asano J, Sato T, Ichinose S, Kajita M, Onai N, Shimizu S, Ohteki T.
    • Journal Title

      Cell Reports

      Volume: 20 Pages: 1050-1060

    • DOI

      10.1016/j.celrep.2017.07.019

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-17H05691, KAKENHI-PROJECT-15H04717, KAKENHI-PROJECT-16K19571, KAKENHI-PROJECT-17H01533
  • [Journal Article] Hyperoxidation of ether-linked phospholipids accelerates neutrophil extracellular trap formation.2017

    • Author(s)
      Yotsumoto Satoshi、Muroi Yuito、Chiba Tatsuya、Ohmura Rio、Yoneyama Maki、Magarisawa Megumi、Dodo Kosuke、Terayama Naoki、Sodeoka Mikiko、Aoyagi Ryohei、Arita Makoto、Arakawa Satoko、Shimizu Shigeomi、Tanaka Masato
    • Journal Title

      Journal, Scientific Reports

      Volume: 7 Pages: 16026-16026

    • DOI

      10.1038/s41598-017-15668-z

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05898, KAKENHI-PLANNED-26110004, KAKENHI-PLANNED-26110005, KAKENHI-PLANNED-26110006, KAKENHI-PROJECT-15H04648, KAKENHI-PROJECT-17H04068, KAKENHI-PROJECT-15K08420, KAKENHI-PROJECT-17H01533
  • [Journal Article] Live Cell Imaging of Mitochondrial Autophagy with a Novel Fluorescent Small Molecule2017

    • Author(s)
      Iwashita Hidefumi、Torii Satoru、Nagahora Noriyoshi、Ishiyama Munetaka、Shioji Kosei、Sasamoto Kazumi、Shimizu Shigeomi、Okuma Kentaro
    • Journal Title

      ACS Chemical Biology

      Volume: 12 Pages: 2546-2551

    • DOI

      10.1021/acschembio.7b00647

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H01533
  • [Journal Article] Ulk1-mediated Atg5-independent macroautophagy mediates elimination of mitochondria from embryonic reticulocytes.2016

    • Author(s)
      Watanabe Y, Honda S, Konishi A, Satoko Arakawa S, Murohashi M, Yamaguchi H, Torii S, Tanabe M, Tanaka S, Warabi E, Shimizu S.
    • Journal Title

      Nat Commun13508

      Volume: 7 Pages: 1-12

    • DOI

      10.1038/ncomms13508

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PUBLICLY-15H01484, KAKENHI-PUBLICLY-15H01554, KAKENHI-PLANNED-26110005, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-16H02670, KAKENHI-PROJECT-15H04926, KAKENHI-PROJECT-25440080, KAKENHI-PROJECT-26430051, KAKENHI-PROJECT-26460485, KAKENHI-PROJECT-15K15491, KAKENHI-PROJECT-15K19004, KAKENHI-PROJECT-15K08420, KAKENHI-PROJECT-16K15230
  • [Journal Article] Golgi membrane‐associated degradation pathway in yeast and mammals2016

    • Author(s)
      H. Yamaguchi, S. Arakawa, T. Kanaseki, T. Miyatsuka, Y. Fujitani, H. Watada, Y. Tsujimoto, S. Shimizu
    • Journal Title

      EMBO J

      Volume: 35 Pages: 1991-2007

    • DOI

      10.15252/embj.201593191

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PUBLICLY-15H01554, KAKENHI-PLANNED-26110005, KAKENHI-PROJECT-15K14519, KAKENHI-PROJECT-15K18860, KAKENHI-PROJECT-15K08420, KAKENHI-PROJECT-16K15230
  • [Journal Article] TRF2 Interacts with Core Histones to Stabilize Chromosome Ends2016

    • Author(s)
      Konishi A, Izumi T, Shimizu S
    • Journal Title

      J. Biol. Chem.

      Volume: 291(39) Pages: 20798-810

    • DOI

      10.1074/jbc.m116.719021

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25440080, KAKENHI-PROJECT-16K15230
  • [Journal Article] Identification of PPM1D as an essential Ulk1 phosphatase for genotoxic stress-induced autophagy2016

    • Author(s)
      S. Torii, T. Yoshida, S. Arakawa, S. Honda, A. Nakanishi, S. Shimizu
    • Journal Title

      EMBO R

      Volume: 11 Pages: 1552-1564

    • DOI

      10.15252/embr.201642565

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PUBLICLY-15H01554, KAKENHI-PLANNED-26110005, KAKENHI-PROJECT-15K08420, KAKENHI-PROJECT-16K15230
  • [Journal Article] Autophagy suppresses cell migration by degrading GEF-H1, a RhoA GEF.2016

    • Author(s)
      T. Yoshida, M. Tsujioka, S. Honda, S. Shimizu
    • Journal Title

      OncoTarget

      Volume: 7 Pages: 34420-34429

    • DOI

      10.18632/oncotarget.8883

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PUBLICLY-15H01554, KAKENHI-PLANNED-26110006, KAKENHI-PROJECT-26293089, KAKENHI-PROJECT-15K19004, KAKENHI-PROJECT-16K15230
  • [Journal Article] Optogenetic activation of axon guidance receptors controls direction of neurite outgrowth.2016

    • Author(s)
      Y. Nasu, A. Benke, S. Arakawa, G. Yoshida, G. Kawamura, S. Manley, S. Shimizu, T. Ozawa
    • Journal Title

      Sci. Rep.

      Volume: 6 Pages: 23976-23976

    • DOI

      10.1038/srep27505

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-15H01554, KAKENHI-PLANNED-26110005, KAKENHI-PROJECT-15J02898, KAKENHI-PROJECT-15K08420, KAKENHI-PROJECT-16K14016, KAKENHI-PROJECT-16K15230, KAKENHI-PROJECT-16K19103, KAKENHI-PROJECT-26220805
  • [Journal Article] A mild and facile synthesis of aryl and alkenyl sulfides via copper-catalyzed deborylthiolation of organoborons with thiosulfonates.2015

    • Author(s)
      Suguru Yoshida, Yasuyuki Sugimura, Yuki Hazama, Yoshitake Nishiyama, Takahisa Yano, Shigeomi Shimizu, Takamitsu Hosoya
    • Journal Title

      Chemical Commun

      Volume: 51 Pages: 16613-16

    • DOI

      10.1039/c5cc07463k

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26350971, KAKENHI-PUBLICLY-15H01554, KAKENHI-PROJECT-15H03118
  • [Journal Article] Direct Thioamination of Arynes via Reaction with Sulfilimines and Migratory N-Arylation.2015

    • Author(s)
      Suguru Yoshida, Takahisa Yano, Yoshihiro Misawa, Yasuyuki Sugimura, Kazunobu Igawa, Shigeomi Shimizu, Katsuhiko Tomooka, Takamitsu Hosoya
    • Journal Title

      J. Am. Chem. Soc.

      Volume: 137 Pages: 14071-14074

    • DOI

      10.1021/jacs.5b10557

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26350971, KAKENHI-PUBLICLY-15H01554, KAKENHI-PROJECT-15H03118
  • [Journal Article] Identification of a novel compound that inhibits both mitochondria-mediated necrosis and apoptosis.2015

    • Author(s)
      S. Arakawa, I. Nakanomyo, Y. Kudo-Sakamoto, H. Akazawa, I. Komuro, S. Shimizu.
    • Journal Title

      Biochem. Biophys. Res. Commun.

      Volume: 467 Pages: 1006-11

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-15H01554
  • [Journal Article] Ulk1-mediated Atg5-independent macroautophagy mediates elimination of mitochondria from embryonic reticulocytes2014

    • Author(s)
      S. Honda, S. Arakawa, Y. Nishida, H. Yamaguchi, E. Ishii, S. Shimizu.
    • Journal Title

      Nat Commun

      Volume: 5 Pages: 4004-4004

    • DOI

      10.1038/ncomms5004

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-22229002, KAKENHI-PROJECT-24659178, KAKENHI-PROJECT-24689020, KAKENHI-PROJECT-25670139, KAKENHI-PROJECT-26670503
  • [Journal Article] Ulk1-mediated Atg5-independent macroautophagy mediates elimination of mitochondria from embryonic reticulocytes.2014

    • Author(s)
      S. Honda, S. Arakawa, Y. Nishida, H. Yamaguchi, E. Ishii, S. Shimizu,
    • Journal Title

      Nature Communications

      Volume: press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22229002
  • [Journal Article] Autophagic cell death and cancer.2014

    • Author(s)
      S. Shimizu, T. Yoshida, M. Tsujioka, S. Arakawa.
    • Journal Title

      Int. J. Mol. Sci.

      Volume: 15 Pages: 3145-3153

    • DOI

      10.3390/ijms15023145

    • NAID

      40019721683

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-22229002, KAKENHI-PUBLICLY-24121708, KAKENHI-PROJECT-24659178, KAKENHI-PROJECT-24689020, KAKENHI-PUBLICLY-25113509, KAKENHI-PROJECT-25670139
  • [Journal Article] Ulk1-mediated Atg5-independent macroautophagy mediates elimination of mitochondria from embryonic reticulocytes.2014

    • Author(s)
      S. Honda, S. Arakawa, Y. Nishida, H. Yamaguchi, E. Ishii, S. Shimizu,
    • Journal Title

      Nature Communications

      Volume: press

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-24121708
  • [Journal Article] Ulk1-mediated Atg5-independent macroautophagy mediates elimination of mitochondria from embryonic reticulocytes.2014

    • Author(s)
      Honda S, Arakawa S, Nishida Y, Yamaguchi H, Ishii E, Shimizu S,
    • Journal Title

      Nature Commun

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670139
  • [Journal Article] Alternative macroautophagy and mitophagy.2014

    • Author(s)
      S. Shimizu, S. Honda, S. Arakawa, H. Yamaguchi
    • Journal Title

      Int J Biochem Cell Biol.

      Volume: 50 Pages: 3145-3153

    • DOI

      10.1016/j.biocel.2014.02.016

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-22229002, KAKENHI-PUBLICLY-24121708, KAKENHI-PROJECT-24659178, KAKENHI-PROJECT-24689020, KAKENHI-PUBLICLY-25113509, KAKENHI-PROJECT-25670139
  • [Journal Article] Inhibition of epithelial cell death by Bcl-2 improved chronic colitis in IL10 KO mice.2013

    • Author(s)
      T. Mizushima, S. Arakawa, Y. Sanada, I. Yoshino, D. Miyazaki, H. Urushima, Y. Tsujimoto, T. Ito, S. Shimizu
    • Journal Title

      Am. J. Pathol.

      Volume: 183 Pages: 1936-1944

    • DOI

      10.1016/j.ajpath.2013.08.012

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22229002, KAKENHI-PUBLICLY-24121708, KAKENHI-PROJECT-24659178, KAKENHI-PROJECT-24689020, KAKENHI-PUBLICLY-25113509, KAKENHI-PUBLICLY-25131710, KAKENHI-PROJECT-25650078, KAKENHI-PROJECT-25670139
  • [Journal Article] Hypertrophy and unconventional cell division of hepatocytes underlie liver regeneration2012

    • Author(s)
      Y. Miyaoka, K. Ebato, H. Kato, S. Arakawa, S. Shimizu, A. Miyajima
    • Journal Title

      Curr. Biol

      Volume: 22 Pages: 1166-75

    • Data Source
      KAKENHI-PROJECT-23657084
  • [Journal Article] Inhibits Vascular Endothelial Growth Factor Expression in Solid Tumor2012

    • Author(s)
      Y. Yoshioka, S. Shimizu, T. Ito, M.Taniguchi, M. Nomura, T. Nishida, Y. Sawa.
    • Journal Title

      J Surg Res

      Volume: 174 Pages: 291-297

    • Data Source
      KAKENHI-PROJECT-23657084
  • [Journal Article] 生体におけるマイトファジーの役割2012

    • Author(s)
      清水重臣
    • Journal Title

      「実験医学」羊土社

      Volume: 30 Pages: 1390-95

    • Data Source
      KAKENHI-PROJECT-23657084
  • [Journal Article] Transformation of an antimicrobial peptide into a plasma membrane- permeable,mitochondria-targeted peptide via the substitution of lysine with arginine2012

    • Author(s)
      I. Nakase, S. Okumura, S. Katayama, H. Hirose, S. Pujals, H. Yamaguchi, S. Arakawa, S. Shimizu, S. Futaki
    • Journal Title

      Chemical Communication

      Volume: 48 Pages: 11097-99

    • Data Source
      KAKENHI-PROJECT-23657084
  • [Journal Article] Shigella targets epithelial tricellular junctions to spread between cells via a noncanonicalclathrin-dependent endocytic pathway2012

    • Author(s)
      M. Fukamatsu, M. Ogawa, S. Arakawa, H.Ashida, M. Suzuki, M. Furuse, K. Nakayama, S. Shimizu, M. Kin, H. Mimuro, C. Sasakawa
    • Journal Title

      Cell Host Microbe

      Volume: 11 Pages: 325-336

    • Data Source
      KAKENHI-PROJECT-23657084
  • [Journal Article] オートファジー細胞死の分子機構とその生体での役割2012

    • Author(s)
      清水重臣
    • Journal Title

      「実験医学」羊土社

      Volume: 30 Pages: 550-5

    • Data Source
      KAKENHI-PROJECT-23657084
  • [Journal Article] Involvement of Beclin 1 in the engulfment of apoptotic cells2012

    • Author(s)
      A. Konishi, S. Arakawa, Z. Yue, S.Shimizu
    • Journal Title

      J. Biol. Chem

      Volume: 287 Pages: 13919-29

    • Data Source
      KAKENHI-PROJECT-23657084
  • [Journal Article] ミトコンドリアの変化2011

    • Author(s)
      清水重臣
    • Journal Title

      「細胞死解析プロトコール」羊土社

      Pages: 108-118

    • Data Source
      KAKENHI-PROJECT-23657084
  • [Journal Article] Spatialcoupling of mTOR and autophagy augments secretory phenotypes2011

    • Author(s)
      M. Narita, A.R.J. Young, S. Arakawa, S.A. Samarajiwa, T. Nakashima, S. Yoshida, S.K. Hong, L.S. Berry, S. Reichelt, M. Ferreira, S. Tavare, K. Inoki, S. Shimizu, M. Narita
    • Journal Title

      Science

      Volume: 332 Pages: 966-970

    • Data Source
      KAKENHI-PROJECT-23657084
  • [Journal Article] Delayed-onset caspase-dependent massive hepatocyte apoptosis upon Fas activation in Bak/Bax-deficient mice2011

    • Author(s)
      H. Hikita, T. Takehara, T. Kodama, S. Shimizu, M. Shigekawa, A. Hosui, T. Miyagi, T. Tatsumi, H. Ishida, Li W, T. Kanto, N. Hiramatsu, S. Shimizu, Y. Tsujimoto, N. Hayashi
    • Journal Title

      Hepatology

      Volume: 54 Pages: 240-251

    • Data Source
      KAKENHI-PROJECT-23657084
  • [Journal Article] Spatial coupling of mTOR and autophagy augments secretory phenotypes.2011

    • Author(s)
      Masako Narita
    • Journal Title

      Science

      Volume: 332 Pages: 966-970

    • DOI

      10.1126/science.1205407

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-22020009, KAKENHI-PUBLICLY-22121505, KAKENHI-PROJECT-22229002, KAKENHI-PROJECT-22770054, KAKENHI-PROJECT-23657084
  • [Journal Article] Stress-activated protein kinase MKK7 regulates axon elongation in the developing cerebral cortex.2011

    • Author(s)
      Yamasaki T, Kawasaki H, Arakawa S, Shimizu K, Shimizu S, Reiner O, Okano H, Nishina S, Azuma N, Penninger JM, Katada T, Nishina H.
    • Journal Title

      Journal of Neuroscience

      Volume: 31 Pages: 16872-16883

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23657084
  • [Journal Article] Stress-activated protein kinase MKK7 regulates axon elongation in thedeveloping cerebral cortex2011

    • Author(s)
      T. Yamasaki, H. Kawasaki, S. Arakawa, K. Shimizu, S. Shimizu, O. Reiner, H. Okano, S. Nishina, N. Azuma, J.M. Penninger, T. Katada, H Nishina
    • Journal Title

      Journal ofNeuroscience

      Volume: 31 Pages: 16872-16883

    • Data Source
      KAKENHI-PROJECT-23657084
  • [Journal Article] Delayed-onset caspase-dependent massive hepatocyte apoptosis upon Fas activation in Bak/Bax-deficient mice.2011

    • Author(s)
      Hikita, H.
    • Journal Title

      Hepatology

      Volume: VOL. 54 Pages: 240-251

    • DOI

      10.1002/hep.24305

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0316, KAKENHI-PROJECT-21590841, KAKENHI-PROJECT-21659188, KAKENHI-PUBLICLY-22020009, KAKENHI-PUBLICLY-22121505, KAKENHI-PROJECT-22229002, KAKENHI-PROJECT-23657084
  • [Journal Article] アポトーシスと非アポトーシス細胞死2011

    • Author(s)
      清水重臣
    • Journal Title

      「臨床血液」教育講演号

    • NAID

      10029769484

    • Data Source
      KAKENHI-PROJECT-23657084
  • [Journal Article] Autophagy takes an alternative pathway2010

    • Author(s)
      S.Shimizu, et al.
    • Journal Title

      Autophagy

      Volume: 6 Pages: 290-291

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22229002
  • [Journal Article] Involvement of JNK in the regulation of autophagic cell death2010

    • Author(s)
      S.Shimizu, et al.
    • Journal Title

      Oncogene

      Volume: 29 Pages: 2070-2082

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22229002
  • [Journal Article] Autophagy takes an alternative pathway2010

    • Author(s)
      S.Shimizu, et al.
    • Journal Title

      Autophagy

      Volume: 6 Pages: 290-291

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-22020009
  • [Journal Article] Autophagy takes an alternative pathway2010

    • Author(s)
      S.Shimizu, et al.
    • Journal Title

      Autophagy

      Volume: 6 Pages: 290-291

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-22121505
  • [Journal Article] Involvement of JNK in the regulation of autophagic cell death.2010

    • Author(s)
      S.Shimizu, et al
    • Journal Title

      Oncogene (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659076
  • [Journal Article] Autophagy takes an alternative pathway2010

    • Author(s)
      S.Shimizu, et al.
    • Journal Title

      Autophagy

      Volume: 6 Pages: 290-291

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659076
  • [Journal Article] Involvement of JNK in the regulation of autophagic cell death2010

    • Author(s)
      S.Shimizu, et al.
    • Journal Title

      Oncogene

      Volume: 29 Pages: 2070-2082

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-22020009
  • [Journal Article] Involvement of JNK in the regulation of autophagic cell death2010

    • Author(s)
      S.Shimizu, et al.
    • Journal Title

      Oncogene

      Volume: 29 Pages: 2070-2082

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659076
  • [Journal Article] Involvement of JNK in the regulation of autophagic cell death2010

    • Author(s)
      S.Shimizu, et al.
    • Journal Title

      Oncogene

      Volume: 29 Pages: 2070-2082

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-22121505
  • [Journal Article] Role of the mitochondrial membrane permeability transition in cell death.2007

    • Author(s)
      Tsujimoto Y & Shimizu S
    • Journal Title

      Apoptosis 5

      Pages: 835-840

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18023024
  • [Journal Article] Furanonaphthoquinones cause apoptosis of cancer cells by inducing the production of reactive oxygen species by the mitochondrial voltage-dependent anion channel.2006

    • Author(s)
      Simamura, E., Hirai, K., Shimada, H., Koyama, J., Niwa, Y., Shimizu, S.
    • Journal Title

      Cancer Biology & Therapy 5

      Pages: 11523-11523

    • Data Source
      KAKENHI-PROJECT-18023024
  • [Journal Article] Mitochondrial membrane permeability transition and cell death.2006

    • Author(s)
      Tsujimoto, Y., Nakagawa, T., Shimizu, S.
    • Journal Title

      Biochim Biophys Acta. 9-10

      Pages: 1297-1297

    • Data Source
      KAKENHI-PROJECT-18023024
  • [Journal Article] Furanonaphthoquinones cause apoptosis of cancer cells by inducing the production of reactive oxygen species by the mitochondrial voltage-dependent anion channel.2006

    • Author(s)
      Simamura, E., Hirai, K., Shimada, H., Koyama, J., Niwa, Y., Shimizu, S.
    • Journal Title

      Cancer Biology & Therapy 5

      Pages: 11523-11523

    • Data Source
      KAKENHI-PROJECT-17390094
  • [Journal Article] Mitochondrial membrane permeability transition and cell death.2006

    • Author(s)
      Tsujimoto, Y., Nakagawa, T., Shimizu, S.
    • Journal Title

      Biochim Biophys Acta. 9-10

      Pages: 1297-1297

    • Data Source
      KAKENHI-PROJECT-17390094
  • [Journal Article] Antiapoptotic function of 17AA(+)WT1 (Wilms' tumor gene) isoforms on the intrinsic apoptosis pathway.2006

    • Author(s)
      Ito, K., Oji, Y., Tatsumi, N, Shimizu, S., et al.
    • Journal Title

      Oncogene 25

      Pages: 4217-4217

    • Data Source
      KAKENHI-PROJECT-17390094
  • [Journal Article] Antiapoptotic function of 17AA(+)WT1 (Wilms' tumor gene) isoforms on the intrinsic apoptosis pathway.2006

    • Author(s)
      Ito, K., Oji, Y., Tatsumi, N., Shimizu, S., et al.
    • Journal Title

      Oncogene 25

      Pages: 4217-4217

    • Data Source
      KAKENHI-PROJECT-18023024
  • [Journal Article] Two distinct Fas-activated signaling pathways revealed by an anti-tumor drug D6092005

    • Author(s)
      L.Zhang, S.Shimizu.Y.Tsujimoto
    • Journal Title

      Oncogene 24

      Pages: 2954-2962

    • Data Source
      KAKENHI-PROJECT-17390094
  • [Journal Article] Two distinct Fas-activated signaling pathways revealed by an anti-tumor drug D6092005

    • Author(s)
      L.Zhang, S.Shimizu, Y.Tsujimoto
    • Journal Title

      Oncogene 24

      Pages: 2954-2962

    • Data Source
      KAKENHI-PROJECT-17025025
  • [Journal Article] Chk2 regulates transcription-independent p53-mediated apoptosis in response to DNA damage.2005

    • Author(s)
      Chen C, Shimizu S, et al.
    • Journal Title

      Biochem Biophys Res Commun 333

      Pages: 427-431

    • Data Source
      KAKENHI-PROJECT-17591331
  • [Journal Article] Chk2 regulates transcription-independent p53-mediated apoptosis in response to DNA damage2005

    • Author(s)
      C.Chen, S.Shimizu, et al.
    • Journal Title

      Biochem Biophys Res Commun. 333

      Pages: 427-431

    • Data Source
      KAKENHI-PROJECT-17390094
  • [Journal Article] Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death.2005

    • Author(s)
      T.Nakagawa, S.Shimizu, et al.
    • Journal Title

      Nature 434

      Pages: 652-658

    • Data Source
      KAKENHI-PROJECT-17390094
  • [Journal Article] Another way to die : autophagic programmed cell death.2005

    • Author(s)
      Tsujimoto Y, Shimizu S.
    • Journal Title

      Cell Death Differ 12

      Pages: 1528-1534

    • Data Source
      KAKENHI-PROJECT-17591331
  • [Journal Article] Chk2 regulates transcription-independent p53-mediated apoptosis in response to DNA damage2005

    • Author(s)
      C.Chen, S.Shimizu, et al.
    • Journal Title

      Biochem Biophys Res Commun. 333

      Pages: 427-431

    • Data Source
      KAKENHI-PROJECT-17025025
  • [Journal Article] Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death.2005

    • Author(s)
      Nakagawa T, Shimizu S, et al.
    • Journal Title

      Nature. 434

      Pages: 652-658

    • Data Source
      KAKENHI-PROJECT-17591331
  • [Journal Article] Two distinct Fas-activated signaling pathways revealed by an antitumor drug D609.2005

    • Author(s)
      Zhang L, Shimizu S, et al.
    • Journal Title

      Oncogene. 24

      Pages: 2954-2962

    • Data Source
      KAKENHI-PROJECT-17591331
  • [Journal Article] Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death.2005

    • Author(s)
      T.Nakagawa, S.Shimizu, et al.
    • Journal Title

      Nature 434

      Pages: 652-658

    • Data Source
      KAKENHI-PROJECT-17025025
  • [Journal Article] A role of Bcl-2 family of proteins in non-apoptotic programmed cell death dependent on autophagy genes.2004

    • Author(s)
      Shimizu, S., et al.
    • Journal Title

      Nature Cell Biol. 6

      Pages: 1221-1228

    • Data Source
      KAKENHI-PROJECT-16023240
  • [Journal Article] Role of the mitochondrial membrane permeability transition in cell death.

    • Author(s)
      Tsujimoto, Y., Shimizu, S.
    • Journal Title

      Apoptosis (印刷中)

    • Data Source
      KAKENHI-PROJECT-17390094
  • [Journal Article] 神経変性疾患とミトコンドリア傷害

    • Author(s)
      清水重臣
    • Journal Title

      神経変性疾患のサイエンス (印刷中)

    • Data Source
      KAKENHI-PROJECT-17390094
  • [Journal Article] Role of the mitochondrial membrane permeability transition in cell death.

    • Author(s)
      Tsujimoto, Y., Shimizu, S.
    • Journal Title

      Apoptosis (印刷中)

    • Data Source
      KAKENHI-PROJECT-18023024
  • [Journal Article] オートファジーの新たな展開とそれによる炎症制御

    • Author(s)
      清水重臣
    • Journal Title

      細胞工学

      Volume: (印刷中)

    • Data Source
      KAKENHI-PROJECT-22247016
  • [Journal Article] 神経変性疾患とミトコンドリア傷害

    • Author(s)
      清水重臣
    • Journal Title

      神経変性疾患のサイエンス (印刷中)

    • Data Source
      KAKENHI-PROJECT-18023024
  • [Journal Article] Atg5非依存性オートファジーの形態学と分子生物学

    • Author(s)
      清水重臣、荒川聡子、西田友哉
    • Journal Title

      顕微鏡

      Volume: (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22247016
  • [Patent] ベンゾチオフェン化合物、該化合物を有効成分とするオルタナティブオートファジー誘導剤及び抗癌剤、並びに抗癌活性を有する化合物をスクリーニングするための方法2013

    • Inventor(s)
      清水重臣、室橋道子、細谷孝充、吉田優
    • Industrial Property Rights Holder
      国立大学法人東京医科歯科大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2013-02-07
    • Overseas
    • Data Source
      KAKENHI-PROJECT-23657084
  • [Patent] ベンゾチオフェン化合物、該化合物を有効成分と するオルタナティブオートファジー誘導剤及び抗癌 剤、並びに抗癌活性を有する化合物をスクリーニン グするための方法2013

    • Inventor(s)
      清水重臣、室橋道子、細谷孝充、 吉田優
    • Industrial Property Rights Holder
      国立大学法人東京医科歯科大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2013-02-07
    • Overseas
    • Data Source
      KAKENHI-PUBLICLY-24121708
  • [Patent] ベンゾチオフェン化合物、該化合物を有効成分とするオルタナティブオートファジー誘導剤及び抗癌剤、並びに抗癌活性を有する化合物をスクリーニングするための 方法2013

    • Inventor(s)
      Shigeomi SHIMIZU, Takamitsu HOSOYA, Michiko MUROHASHI, Suguru YOSHIDA
    • Industrial Property Rights Holder
      国立大学法人東京医科歯科大学
    • Filing Date
      2013-02-07
    • Overseas
    • Data Source
      KAKENHI-PROJECT-23657084
  • [Patent] ベンゾチオフェン化合物、該化合物を有効成分とするオルタナティブオートファジー誘導剤及び抗癌剤、並びに抗癌活性を有する化合物をスクリーニングするための方法2013

    • Inventor(s)
      清水重臣、室橋道子、細谷孝充、 吉田優
    • Industrial Property Rights Holder
      国立大学法人東京医科歯科大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2013-02-07
    • Overseas
    • Data Source
      KAKENHI-PROJECT-22229002
  • [Patent] ベンゾチオフェン化合物、並びに該化合物を有効成分とするオルタナティブオートファジー誘導剤及び抗癌剤2012

    • Inventor(s)
      清水重臣 室橋道子 細谷孝充 吉田満
    • Industrial Property Rights Holder
      国立大学法人東京医科歯科大学
    • Industrial Property Number
      2012-026373
    • Filing Date
      2012
    • Data Source
      KAKENHI-PROJECT-23657084
  • [Patent] 抗癌活性を有する化合物をスクリーニングするための方法2012

    • Inventor(s)
      清水重臣 室橋道子
    • Industrial Property Rights Holder
      国立大学法人東京医科歯科大学
    • Industrial Property Number
      2012-026377
    • Filing Date
      2012
    • Data Source
      KAKENHI-PROJECT-23657084
  • [Patent] 抗癌活性を有する化合物をスクリーニングするための方法2012

    • Inventor(s)
      清水重臣、室橋道子
    • Industrial Property Rights Holder
      国立大学法人東京医科歯科大学
    • Industrial Property Number
      2012-026377
    • Filing Date
      2012-02-09
    • Data Source
      KAKENHI-PROJECT-23657084
  • [Patent] ベンゾチオフェン化合物、並びに該化合物を有効成分とするオルタナティブオートファジー誘導剤及び抗癌剤2012

    • Inventor(s)
      清水重臣、細谷孝充、室橋道子、吉田優
    • Industrial Property Rights Holder
      国立大学法人東京医科歯科大学出願
    • Industrial Property Number
      2012-026373
    • Filing Date
      2012-02-09
    • Data Source
      KAKENHI-PROJECT-23657084
  • [Patent] ベンゾチオフェン化合物、並びに該化合物を有効成分とするオルタナティブオートファジー誘導剤及び抗癌剤2012

    • Inventor(s)
      清水重臣, 室橋道子, 細谷孝充, 吉田満
    • Industrial Property Rights Holder
      国立大学法人東京医科歯科大学
    • Industrial Property Number
      2012-026373
    • Filing Date
      2012-02-09
    • Data Source
      KAKENHI-PROJECT-22229002
  • [Patent] 抗癌活性を有する化合物をスクリーニングするための方法2012

    • Inventor(s)
      清水重臣, 室橋道子
    • Industrial Property Rights Holder
      国立大学法人東京医科歯科大学
    • Industrial Property Number
      2012-026377
    • Filing Date
      2012-02-09
    • Data Source
      KAKENHI-PROJECT-22229002
  • [Presentation] 新規オートファジーによる インスリン分解機構2020

    • Author(s)
      清水重臣
    • Organizer
      7th Diabetes Research Meeting
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H01533
  • [Presentation] 細胞死、ミトコンドリアと臓器不全2020

    • Author(s)
      清水重臣
    • Organizer
      第47回 日本集中治療医学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H01533
  • [Presentation] 2種類のオートファジーによる ミトコンドリアqualityの調節2020

    • Author(s)
      清水重臣
    • Organizer
      AMED村山班 TR会議
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H01533
  • [Presentation] オートファジー誘導物質による薬剤誘導性腸炎緩和効果の検討2019

    • Author(s)
      安枝明日香, 荻野崇之, 清水重臣, 西村潤一, 室橋道子, 渡部嘉文, 三吉範克,高橋秀和, 原口直紹, 畑泰司, 松田宙, 水島恒和, 森正樹, 土岐祐一郎
    • Organizer
      第56回日本消化器免疫学会総会
    • Data Source
      KAKENHI-PROJECT-17K10632
  • [Presentation] Molecular mechanisms and physiological roles of Atg5-independent mitophagy2019

    • Author(s)
      Shigeomi Shimizu
    • Organizer
      ASMRM & J-mit
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-17H06414
  • [Presentation] Molecular mechanisms and physiological roles of Atg5-independent mitophagy2019

    • Author(s)
      Shigeomi Shimizu
    • Organizer
      ASMRM & J-mit
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-17H06413
  • [Presentation] Atg5非依存的オートファジーの 分子機構と生理機2019

    • Author(s)
      清水重臣
    • Organizer
      第12回オートファジー研究会
    • Data Source
      KAKENHI-PROJECT-17H01533
  • [Presentation] New insights into the mechanism of Golgi-mediated alternative autophagy using chemical biology approach2019

    • Author(s)
      Shigeomi Shimizu
    • Organizer
      International Symposium of Autophagy
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H01533
  • [Presentation] 細胞死とオートファジーのクロストーク2019

    • Author(s)
      清水重臣
    • Organizer
      日本Cell Death学会
    • Data Source
      KAKENHI-PROJECT-17H01533
  • [Presentation] Autophagy induction of epithelium alleviate colitis in DSS model mice2019

    • Author(s)
      Asuka Yasueda, Shigeomi Shimizu, Junichi Nishimura, Michiko Murohashi, Takayuki Ogino, Yoshifumi Watanabe, Koji Wakame, Kenichi Komatsu, Norikatsu Miyoshi, Hidekazu Takahashi ,Mamoru Uemura, Chu Matsuda, Tsunekazu Mizushima, Masaki Mori, Yuichiro Doki,
    • Organizer
      UEG WEEK 2019 Bercelona (Spain)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10632
  • [Presentation] Molecular mechanisms and physiological roles of alternative autophagy2019

    • Author(s)
      Shigeomi Shimizu
    • Organizer
      The 92nd Annual Meeting of the Japanese Biochemical Society
    • Data Source
      KAKENHI-PLANNED-17H06414
  • [Presentation] New insights into the mechanism of Golgi-mediated alternative autophagy using chemical biology approach2019

    • Author(s)
      Shigeomi Shimizu
    • Organizer
      International Symposium of Autophagy
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-17H06413
  • [Presentation] Molecular mechanisms and physiological roles of Atg5-independent mitophagy2019

    • Author(s)
      Shigeomi Shimizu
    • Organizer
      ASMRM & J-mit
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H01533
  • [Presentation] New insights into the mechanism of Golgi-mediated alternative autophagy using chemical biology approach2019

    • Author(s)
      Shigeomi Shimizu
    • Organizer
      International Symposium of Autophagy
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-17H06414
  • [Presentation] Molecular mechanisms and physiological roles of alternative autophagy2019

    • Author(s)
      Shigeomi Shimizu
    • Organizer
      The 92nd Annual Meeting of the Japanese Biochemical Society
    • Data Source
      KAKENHI-PROJECT-17H01533
  • [Presentation] オートファジーと疾患2018

    • Author(s)
      清水重臣
    • Organizer
      第6回AAA会
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-17H06413
  • [Presentation] オートファジーと疾患2018

    • Author(s)
      清水重臣
    • Organizer
      第6回AAA会
    • Invited
    • Data Source
      KAKENHI-PLANNED-17H06414
  • [Presentation] Development of molecularly targeted anticancer agents based on the regulation of autophagic cell death2017

    • Author(s)
      清水重臣
    • Organizer
      第76回日本癌学会
    • Data Source
      KAKENHI-PROJECT-16K15230
  • [Presentation] 新規オートファジーの分子機構とその破綻による疾患2017

    • Author(s)
      清水重臣
    • Organizer
      第22回 日本病態プロテアーゼ学会
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-17H06413
  • [Presentation] オートファジーが関わる細胞死2017

    • Author(s)
      清水重臣
    • Organizer
      日本Cell Death学会
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-17H06413
  • [Presentation] Development of molecularly targeted anticancer agents based on the regulation of autophagic cell death2017

    • Author(s)
      清水重臣
    • Organizer
      第76回日本癌学会
    • Invited
    • Data Source
      KAKENHI-PLANNED-17H06414
  • [Presentation] オートファジーが関わる細胞死2017

    • Author(s)
      清水重臣
    • Organizer
      日本Cell Death学会
    • Data Source
      KAKENHI-PROJECT-16K15230
  • [Presentation] Development of molecularly targeted anticancer agents based on the regulation of autophagic cell death2017

    • Author(s)
      清水重臣
    • Organizer
      第76回日本癌学会
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-17H06413
  • [Presentation] 新規オートファジーの分子機構とその破綻による疾患2017

    • Author(s)
      清水重臣
    • Organizer
      第22回 日本病態プロテアーゼ学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K15230
  • [Presentation] オートファジーが関わる細胞死2017

    • Author(s)
      清水重臣
    • Organizer
      日本Cell Death学会
    • Invited
    • Data Source
      KAKENHI-PLANNED-17H06414
  • [Presentation] 新規オートファジーの分子機構とその破綻による疾患2017

    • Author(s)
      清水重臣
    • Organizer
      第22回 日本病態プロテアーゼ学会
    • Invited
    • Data Source
      KAKENHI-PLANNED-17H06414
  • [Presentation] Identification of natural product against fatty liver disease based on the induction of alternative autophagy2016

    • Author(s)
      Shimizu S
    • Organizer
      ICNIM2016
    • Place of Presentation
      Hotel Royton, Sapporo
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-15H01554
  • [Presentation] Alternative Autophagy is Essential for Neuronal Cell Maintenance2016

    • Author(s)
      Shimizu S
    • Organizer
      Brain Protein Aging and Dementia Control International Workshop
    • Place of Presentation
      Kakuyu Kaikan in Nagoya University, Nagoya
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15230
  • [Presentation] Mitophagy and alternative autophagy2016

    • Author(s)
      Shimizu S
    • Organizer
      The 13th Conference of Asian Society for Mitochondrial Research and Medicine
    • Place of Presentation
      TKP Garden City Shinagawa, Shinagawa
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15230
  • [Presentation] Molecular mechanisms of Atg5-independent alternative autophagy2016

    • Author(s)
      Shimizu S
    • Organizer
      Gordon Research Conference.
    • Place of Presentation
      ロスアンジェルス(米国)
    • Year and Date
      2016-03-20
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-15H01554
  • [Presentation] Identification of natural product against fatty liver disease based on the induction of alternative autophagy2016

    • Author(s)
      Shimizu S
    • Organizer
      ICNIM2016
    • Place of Presentation
      Hotel Royton, Sapporo
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15230
  • [Presentation] Macroautophagy mediates elimination of mitochondria from embryonic reticulocytes2016

    • Author(s)
      清水重臣
    • Organizer
      第78回日本血液学会
    • Place of Presentation
      パシフィコ横浜, 横浜
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K15230
  • [Presentation] Macroautophagy mediates elimination of mitochondria from embryonic reticulocytes2016

    • Author(s)
      清水重臣
    • Organizer
      第78回日本血液学会
    • Place of Presentation
      パシフィコ横浜、横浜
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-15H01554
  • [Presentation] Alternative Autophagy is Essential for Neuronal Cell Maintenance2016

    • Author(s)
      Shimizu S
    • Organizer
      Brain Protein Aging and Dementia Control International Workshop
    • Place of Presentation
      Kakuyu Kaikan in Nagoya University, Nagoya
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-15H01554
  • [Presentation] Mitophagy and alternative autophagy2016

    • Author(s)
      Shimizu S
    • Organizer
      The 13th Conference of Asian Society for Mitochondrial Research and Medicine
    • Place of Presentation
      TKP Garden City Shinagawa, Shinagawa
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-15H01554
  • [Presentation] Biological Roles of Autophagic Cell Death2015

    • Author(s)
      Shimizu S
    • Organizer
      Japan Australia Meeting on Cell Death
    • Place of Presentation
      メルボルン(オーストラリア)
    • Year and Date
      2015-10-21
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-15H01554
  • [Presentation] Development of Small Compound against Polyglutamine Diseases based on the Regulation of Alternative Autophagy2015

    • Author(s)
      Shimizu S
    • Organizer
      Brain Protein Aging and Dementia Control 1st InternationalSymposium
    • Place of Presentation
      野依記念学術交流館(愛知県・名古屋市)
    • Year and Date
      2015-10-09
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-15H01554
  • [Presentation] オートファジー破綻に起因する発癌機構の解明とその抗癌剤開発への応用2014

    • Author(s)
      清水重臣
    • Organizer
      第13回南大阪癌フォーラム
    • Place of Presentation
      堺市
    • Year and Date
      2014-04-19
    • Invited
    • Data Source
      KAKENHI-PROJECT-25670139
  • [Presentation] オートファジー破綻に起因する発癌機構の解明とその抗癌剤開発への応用2014

    • Author(s)
      清水重臣
    • Organizer
      第13回南大阪癌フォーラム
    • Place of Presentation
      堺市
    • Year and Date
      2014-04-19
    • Invited
    • Data Source
      KAKENHI-PROJECT-22229002
  • [Presentation] 新しく発見したオートファジー機構とオルガネラ分解2014

    • Author(s)
      清水重臣
    • Organizer
      第57回日本神経化学会大会
    • Place of Presentation
      奈良市
    • Year and Date
      2014-09-29
    • Invited
    • Data Source
      KAKENHI-PROJECT-25670139
  • [Presentation] 新しく発見したオートファジー機構とオルガネラ分解2014

    • Author(s)
      清水重臣
    • Organizer
      第57回日本神経化学会大会
    • Place of Presentation
      奈良市
    • Year and Date
      2014-09-29
    • Invited
    • Data Source
      KAKENHI-PROJECT-22229002
  • [Presentation] 新しく発見したオートファジーと肝疾患2014

    • Author(s)
      清水重臣
    • Organizer
      第21回 肝細胞研究会
    • Place of Presentation
      文京区
    • Year and Date
      2014-06-28
    • Invited
    • Data Source
      KAKENHI-PROJECT-25670139
  • [Presentation] 新しく発見したオートファジーと肝疾患2014

    • Author(s)
      清水重臣
    • Organizer
      第21回 肝細胞研究会
    • Place of Presentation
      文京区
    • Year and Date
      2014-06-28
    • Invited
    • Data Source
      KAKENHI-PROJECT-22229002
  • [Presentation] オートファジーと細胞死のクロストーク2013

    • Author(s)
      清水重臣
    • Organizer
      第22回日本Cell Death学会
    • Place of Presentation
      京都
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-24121708
  • [Presentation] Biological roles of Autophagic cell death2013

    • Author(s)
      Shimizu S
    • Organizer
      第86回日本生化学会
    • Place of Presentation
      横浜
    • Invited
    • Data Source
      KAKENHI-PROJECT-22229002
  • [Presentation] Biological Roles of Autophagic Cell Death” CSH Asia conference on Mechanisms and Functions of Non-apoptotic Cell Death2013

    • Author(s)
      Shimizu S
    • Organizer
      CSH Asia conference on Mechanisms and Functions of Non-apoptotic Cell Death
    • Place of Presentation
      Suzhou, China
    • Invited
    • Data Source
      KAKENHI-PROJECT-25670139
  • [Presentation] Mitophagy is regulated by Ulk1-dependent alternative macroautophagy during erythrocyte maturation2013

    • Author(s)
      Shimizu S
    • Organizer
      International Symposium on Mitochondria
    • Place of Presentation
      Tokyo, Japan
    • Invited
    • Data Source
      KAKENHI-PROJECT-22229002
  • [Presentation] Mitophagy is regulated by Ulk1-dependent alternative macroautophagy during erythrocyte maturation2013

    • Author(s)
      Shimizu S
    • Organizer
      International Symposium on Mitochondria
    • Place of Presentation
      Tokyo, Japan
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-24121708
  • [Presentation] オートファジーと細胞死のクロストーク2013

    • Author(s)
      清水重臣
    • Organizer
      第22回日本Cell Death学会
    • Place of Presentation
      京都
    • Invited
    • Data Source
      KAKENHI-PROJECT-22229002
  • [Presentation] Biological Roles of Autophagic Cell Death2013

    • Author(s)
      Shimizu S
    • Organizer
      CSH Asia conference on Mechanisms and Functions of Non-apoptotic Cell Death
    • Place of Presentation
      Suzhou, China
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-24121708
  • [Presentation] Biological Roles of Autophagic Cell Death2013

    • Author(s)
      Shimizu S
    • Organizer
      第86回日本生化学会
    • Place of Presentation
      横浜
    • Invited
    • Data Source
      KAKENHI-PROJECT-25670139
  • [Presentation] Biological Roles of Autophagic Cell Death2013

    • Author(s)
      Shimizu S
    • Organizer
      CSH Asia conference on Mechanisms and Functions of Non-apoptotic Cell Death
    • Place of Presentation
      Suzhou, China
    • Invited
    • Data Source
      KAKENHI-PROJECT-22229002
  • [Presentation] オートファジーと細胞死のクロストーク2013

    • Author(s)
      清水重臣
    • Organizer
      第22回日本Cell Death学会
    • Place of Presentation
      京都
    • Invited
    • Data Source
      KAKENHI-PROJECT-25670139
  • [Presentation] Mitophagy is regulated by Ulk1-dependent alternative macroautophagy during erythrocyte maturation2013

    • Author(s)
      Shimizu S
    • Organizer
      International Symposium on Mitochondria
    • Place of Presentation
      Tokyo, Japan
    • Invited
    • Data Source
      KAKENHI-PROJECT-25670139
  • [Presentation] Molecular Mechanisms and Physiological Roles of Atg5/Atg7-independent Macroautophagy2012

    • Author(s)
      Shigeomi Shimizu
    • Organizer
      The 6th Symposium on Autophagy
    • Place of Presentation
      名護市
    • Year and Date
      2012-10-28
    • Data Source
      KAKENHI-PUBLICLY-24121708
  • [Presentation] 様々なストレスに対応する為に機能するオートファジー2012

    • Author(s)
      清水重臣
    • Organizer
      第16回日本統合医療学会
    • Place of Presentation
      豊中市
    • Invited
    • Data Source
      KAKENHI-PROJECT-22229002
  • [Presentation] Alternative Macroautophagy and Cancer2012

    • Author(s)
      Shigeomi Shimizu
    • Organizer
      第71回日本癌学会
    • Place of Presentation
      札幌市
    • Year and Date
      2012-09-19
    • Data Source
      KAKENHI-PUBLICLY-24121708
  • [Presentation] Alternative Macroautophagy and Cancer2012

    • Author(s)
      Shigeomi Shimizu
    • Organizer
      第71回日本癌学会
    • Place of Presentation
      札幌市
    • Data Source
      KAKENHI-PROJECT-22229002
  • [Presentation] Alternative Macroautophagy and Cancer2012

    • Author(s)
      Shigeomi Shimizu
    • Organizer
      第71回日本癌学会
    • Place of Presentation
      札幌市
    • Data Source
      KAKENHI-PROJECT-23657084
  • [Presentation] 放射線によって誘導される様々な細胞死とオートファジー2012

    • Author(s)
      清水重臣
    • Organizer
      第2回分子状水素医学シンポジウム
    • Year and Date
      2012-02-11
    • Data Source
      KAKENHI-PROJECT-23657084
  • [Presentation] 様々なストレスに対応する為に機能するオートファジー2012

    • Author(s)
      清水重臣
    • Organizer
      第16回日本統合医療学
    • Place of Presentation
      豊中市
    • Year and Date
      2012-12-08
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-24121708
  • [Presentation] 様々なストレスに対応する為に機能するオートファジー2012

    • Author(s)
      清水重臣
    • Organizer
      第16回日本統合医療学会
    • Year and Date
      2012-12-09
    • Data Source
      KAKENHI-PROJECT-23657084
  • [Presentation] Molecular Mechanisms and Physiological Roles of Atg5/Atg7-independent Macroautophagy2012

    • Author(s)
      Shigeomi Shimizu
    • Organizer
      The 6th Symposium on Autophagy
    • Place of Presentation
      名護市
    • Data Source
      KAKENHI-PROJECT-22229002
  • [Presentation] Molecular Mechanisms and Physiological Roles of Atg5/Atg7-independent Macroautophagy2012

    • Author(s)
      Shigeomi Shimizu
    • Organizer
      The 6th Symposium on Autophagy
    • Place of Presentation
      名護市
    • Data Source
      KAKENHI-PROJECT-23657084
  • [Presentation] Maintenance of tissue homeostasis by dying cells and autophagy2012

    • Author(s)
      清水重臣
    • Organizer
      第35回日本分子生物学会
    • Place of Presentation
      福岡市
    • Year and Date
      2012-12-11
    • Data Source
      KAKENHI-PUBLICLY-24121708
  • [Presentation] なぜ赤血球にはミトコンドリアがないのか?~オートファジーの働き2012

    • Author(s)
      清水重臣
    • Organizer
      第3回ミトコンドリアとDDS
    • Year and Date
      2012-07-07
    • Data Source
      KAKENHI-PROJECT-23657084
  • [Presentation] Molecular Mechanisms andPhysiological Roles of Atg5/Atg7- independent Macroautophagy2012

    • Author(s)
      Shimizu S
    • Organizer
      The 6th Symposium on Autophagy
    • Year and Date
      2012-10-30
    • Data Source
      KAKENHI-PROJECT-23657084
  • [Presentation] Alternative Macroautophagy and Cancer2012

    • Author(s)
      清水重臣
    • Organizer
      第71回日本癌学会
    • Year and Date
      2012-09-19
    • Data Source
      KAKENHI-PROJECT-23657084
  • [Presentation] Maintenance of tissue homeostasis by dying cells and autophagy2012

    • Author(s)
      清水重臣
    • Organizer
      第35回日本分子生物学会
    • Place of Presentation
      福岡市
    • Data Source
      KAKENHI-PROJECT-22229002
  • [Presentation] Maintenance of tissue homeostasis by dying cells and autophagy2012

    • Author(s)
      清水重臣
    • Organizer
      第35回日本分子生物学会
    • Year and Date
      2012-12-13
    • Data Source
      KAKENHI-PROJECT-23657084
  • [Presentation] アポトーシスと非アポトーシス細胞死2011

    • Author(s)
      清水重臣
    • Organizer
      第73回日本血液学会
    • Place of Presentation
      名古屋市(招待講演)
    • Year and Date
      2011-10-14
    • Data Source
      KAKENHI-PUBLICLY-22121505
  • [Presentation] Alternative macroautophagy2011

    • Author(s)
      Shigeomi Shimizu
    • Organizer
      Parkinson Disease and Mitophagy
    • Place of Presentation
      文京区
    • Year and Date
      2011-06-11
    • Data Source
      KAKENHI-PROJECT-22229002
  • [Presentation] 細胞死とオートファジーのクロストーク2011

    • Author(s)
      清水重臣
    • Organizer
      日本Cell Death学会
    • Year and Date
      2011-07-29
    • Data Source
      KAKENHI-PROJECT-23657084
  • [Presentation] 様々な疾患を惹起するミトコンドリア細胞死孔の解析2011

    • Author(s)
      清水重臣
    • Organizer
      第84回日本生化学会
    • Place of Presentation
      京都市
    • Year and Date
      2011-09-24
    • Data Source
      KAKENHI-PUBLICLY-22121505
  • [Presentation] オートファジーを標的とした難治疾患克服への戦略2011

    • Author(s)
      清水重臣
    • Organizer
      新適塾「難病への挑戦」(招待講演)
    • Place of Presentation
      豊中市
    • Data Source
      KAKENHI-PROJECT-23657084
  • [Presentation] オートファジーを標的とした難治疾患克服への戦略2011

    • Author(s)
      清水重臣
    • Organizer
      金沢大学がん進展制御研究所セミナー
    • Year and Date
      2011-09-27
    • Data Source
      KAKENHI-PROJECT-23657084
  • [Presentation] Alternative macroautophagy2011

    • Author(s)
      Shigeomi Shimizu
    • Organizer
      Parkinson Disease and Mitophagy
    • Place of Presentation
      文京区
    • Year and Date
      2011-06-11
    • Data Source
      KAKENHI-PUBLICLY-22121505
  • [Presentation] 様々な疾患を惹起するミトコンドリア細胞死孔の解析2011

    • Author(s)
      清水重臣
    • Organizer
      第84回日本生化学会
    • Place of Presentation
      京都市
    • Year and Date
      2011-09-24
    • Data Source
      KAKENHI-PUBLICLY-22020009
  • [Presentation] 細胞死とオートファジーのクロストーク2011

    • Author(s)
      清水重臣
    • Organizer
      日本Cell Death学会
    • Place of Presentation
      文京区
    • Year and Date
      2011-07-29
    • Data Source
      KAKENHI-PUBLICLY-22121505
  • [Presentation] 生体で見られる様々な細胞死とオートファジー2011

    • Author(s)
      清水重臣
    • Organizer
      第1回横断的腫瘍フォーラム
    • Place of Presentation
      吹田市(招待講演)
    • Year and Date
      2011-12-07
    • Data Source
      KAKENHI-PROJECT-22229002
  • [Presentation] アポトーシスと非アポトーシス細胞死2011

    • Author(s)
      清水重臣
    • Organizer
      第73回日本血液学会
    • Data Source
      KAKENHI-PROJECT-23657084
  • [Presentation] アポトーシスと非アポトーシス細胞死2011

    • Author(s)
      清水重臣
    • Organizer
      第73回日本血液学会
    • Place of Presentation
      名古屋市(招待講演)
    • Year and Date
      2011-10-14
    • Data Source
      KAKENHI-PROJECT-22229002
  • [Presentation] Various Types of Cell Death and Autophagy2011

    • Author(s)
      Shigeomi Shimizu
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      横浜市
    • Year and Date
      2011-12-15
    • Data Source
      KAKENHI-PUBLICLY-22020009
  • [Presentation] オートファジーを標的とした難治疾患克服への戦略2011

    • Author(s)
      清水重臣
    • Organizer
      新適塾「難病への挑戦」
    • Place of Presentation
      豊中市(招待講演)
    • Year and Date
      2011-09-02
    • Data Source
      KAKENHI-PUBLICLY-22121505
  • [Presentation] アポトーシスと非アポトーシス細胞死2011

    • Author(s)
      清水重臣
    • Organizer
      第73回日本血液学会
    • Place of Presentation
      名古屋市(招待講演)
    • Year and Date
      2011-10-14
    • Data Source
      KAKENHI-PUBLICLY-22020009
  • [Presentation] オートファジーを標的とした難治疾患克服への戦略2011

    • Author(s)
      清水重臣
    • Organizer
      新適塾「難病への挑戦」
    • Place of Presentation
      豊中市(招待講演)
    • Year and Date
      2011-09-02
    • Data Source
      KAKENHI-PROJECT-22229002
  • [Presentation] オートファジーと神経変性疾患2011

    • Author(s)
      清水重臣
    • Organizer
      「病態に根ざしたALSの新規治療法開発班」平成23年度ワークショップ
    • Place of Presentation
      千代田区(招待講演)
    • Year and Date
      2011-09-22
    • Data Source
      KAKENHI-PUBLICLY-22020009
  • [Presentation] Various Types of Cell Death and Autophagy2011

    • Author(s)
      Shigeomi Shimizu
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      横浜市
    • Year and Date
      2011-12-15
    • Data Source
      KAKENHI-PROJECT-22229002
  • [Presentation] 生体で見られる様々な細胞死とオートファジー2011

    • Author(s)
      清水重臣
    • Organizer
      第1回横断的腫瘍フォーラム
    • Place of Presentation
      吹田市(招待講演)
    • Year and Date
      2011-12-07
    • Data Source
      KAKENHI-PUBLICLY-22020009
  • [Presentation] Alternative macroautophagy2011

    • Author(s)
      Shigeomi Shimizu
    • Organizer
      Parkinson Disease and Mitophagy
    • Place of Presentation
      文京区
    • Year and Date
      2011-06-11
    • Data Source
      KAKENHI-PUBLICLY-22020009
  • [Presentation] オートファジーを標的とした難治疾患克服への戦略2011

    • Author(s)
      清水重臣
    • Organizer
      新適塾「難病への挑戦」第7回
    • Year and Date
      2011-09-02
    • Data Source
      KAKENHI-PROJECT-23657084
  • [Presentation] 細胞死を司るミトコンドリア孔の解析2011

    • Author(s)
      清水重臣
    • Organizer
      過渡的複合体シンポジウム
    • Year and Date
      2011-07-21
    • Data Source
      KAKENHI-PROJECT-23657084
  • [Presentation] 生体で見られる様々な細胞死とオートファジー2011

    • Author(s)
      清水重臣
    • Organizer
      第1回横断的腫瘍フォーラム
    • Year and Date
      2011-12-07
    • Data Source
      KAKENHI-PROJECT-23657084
  • [Presentation] 様々な疾患を惹起するミトコンドリア細胞死孔の解析2011

    • Author(s)
      清水重臣
    • Organizer
      第84回日本生化学会
    • Place of Presentation
      京都市
    • Year and Date
      2011-09-24
    • Data Source
      KAKENHI-PROJECT-22229002
  • [Presentation] 生体で見られる様々な細胞死とオートファジー2011

    • Author(s)
      清水重臣
    • Organizer
      第1回横断的腫瘍フォーラム
    • Place of Presentation
      吹田市(招待講演)
    • Year and Date
      2011-12-07
    • Data Source
      KAKENHI-PUBLICLY-22121505
  • [Presentation] Alternativemacroautophagy International Symposium2011

    • Author(s)
      Shimizu S.
    • Organizer
      Parkinson Disease and Mitophagy
    • Year and Date
      2011-06-11
    • Data Source
      KAKENHI-PROJECT-23657084
  • [Presentation] オートファジーと神経変性疾患2011

    • Author(s)
      清水重臣
    • Organizer
      「病態に根ざしたALSの新規治療法開発班」平成23年度ワークショップ
    • Place of Presentation
      千代田区(招待講演)
    • Year and Date
      2011-09-22
    • Data Source
      KAKENHI-PUBLICLY-22121505
  • [Presentation] 細胞死とオートファジーのクロストーク2011

    • Author(s)
      清水重臣
    • Organizer
      日本Cell Death学会
    • Place of Presentation
      文京区
    • Year and Date
      2011-07-29
    • Data Source
      KAKENHI-PROJECT-22229002
  • [Presentation] オートファジーと神経変性疾患2011

    • Author(s)
      清水重臣
    • Organizer
      「病態に根ざしたALSの新規治療法開発班」平成23年度ワークショップ(招待講演)
    • Place of Presentation
      千代田区
    • Data Source
      KAKENHI-PROJECT-23657084
  • [Presentation] 細胞死とオートファジーのクロストーク2011

    • Author(s)
      清水重臣
    • Organizer
      日本Cell Death学会
    • Place of Presentation
      文京区
    • Year and Date
      2011-07-29
    • Data Source
      KAKENHI-PUBLICLY-22020009
  • [Presentation] 様々な疾患を惹起するミトコンドリア細胞死孔の解析2011

    • Author(s)
      清水重臣
    • Organizer
      第84回日本生化学会
    • Year and Date
      2011-09-24
    • Data Source
      KAKENHI-PROJECT-23657084
  • [Presentation] アポトーシスと非アポトーシス細胞死2011

    • Author(s)
      清水重臣
    • Organizer
      第73回日本血液学会(招待講演)
    • Place of Presentation
      名古屋市
    • Data Source
      KAKENHI-PROJECT-23657084
  • [Presentation] オートファジーと神経変性疾患病態に根ざしたALSの新規治療法開発班2011

    • Author(s)
      清水重臣
    • Organizer
      平成23年度ワークショップ
    • Year and Date
      2011-09-22
    • Data Source
      KAKENHI-PROJECT-23657084
  • [Presentation] オートファジーと神経変性疾患2011

    • Author(s)
      清水重臣
    • Organizer
      「病態に根ざしたALSの新規治療法開発班」平成23年度ワークショップ
    • Place of Presentation
      千代田区(招待講演)
    • Year and Date
      2011-09-22
    • Data Source
      KAKENHI-PROJECT-22229002
  • [Presentation] Alternative macroautophagy2011

    • Author(s)
      Shigeomi Shimizu
    • Organizer
      Parkinson Disease and Mitophagy
    • Place of Presentation
      文京区
    • Data Source
      KAKENHI-PROJECT-23657084
  • [Presentation] オートファジーを標的とした難治疾患克服への戦略2011

    • Author(s)
      清水重臣
    • Organizer
      新適塾「難病への挑戦」
    • Place of Presentation
      豊中市(招待講演)
    • Year and Date
      2011-09-02
    • Data Source
      KAKENHI-PUBLICLY-22020009
  • [Presentation] Various Types of Cell Death and Autophagy2011

    • Author(s)
      Shigeomi Shimizu
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      横浜市
    • Data Source
      KAKENHI-PROJECT-23657084
  • [Presentation] Various Types of Cell Death and Autophagy2011

    • Author(s)
      Shigeomi Shimizu
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      横浜市
    • Year and Date
      2011-12-15
    • Data Source
      KAKENHI-PUBLICLY-22121505
  • [Presentation] A critical role for the autophagy gene Ulk1 in Atg5-independent alternative macroautophagy2010

    • Author(s)
      Shimizu S.
    • Organizer
      Gordon Conference
    • Place of Presentation
      イタリア
    • Year and Date
      2010-04-29
    • Data Source
      KAKENHI-PROJECT-22247016
  • [Presentation] Various Types of CellDeath and Autophagy2010

    • Author(s)
      Shimizu S
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23657084
  • [Presentation] A critical role for the autophagy gene Ulk1 in Atg5- independent alternative macroautophagy2010

    • Author(s)
      S.Shimizu
    • Organizer
      Gordon Conference
    • Place of Presentation
      Lucca, Italy
    • Year and Date
      2010-04-25
    • Data Source
      KAKENHI-PUBLICLY-22121505
  • [Presentation] Discovery of Atg5/Atg7-independent alternative macroautophagy2010

    • Author(s)
      S.Shimizu
    • Organizer
      6^<th> Institute network symposium
    • Place of Presentation
      Kanazawa
    • Year and Date
      2010-06-25
    • Data Source
      KAKENHI-PUBLICLY-22121505
  • [Presentation] A critical role for the autophagy gene Ulkl in Atg5- independent alternative macroautophagy2010

    • Author(s)
      S.Shimizu
    • Organizer
      Gordon Conference
    • Place of Presentation
      Italy
    • Year and Date
      2010-04-25
    • Data Source
      KAKENHI-PROJECT-22229002
  • [Presentation] A critical role for the autophagy gene U1k1 in Atg5- independent alternative macroautophagy2010

    • Author(s)
      S.Shimizu
    • Organizer
      Gordon Conference
    • Place of Presentation
      Italy
    • Year and Date
      2010-04-25
    • Data Source
      KAKENHI-PROJECT-21659076
  • [Presentation] Discovery of Atg5/Atg7-independent alternative macroautophagy2010

    • Author(s)
      S.Shimizu
    • Organizer
      6^<th> Institute network symposium
    • Place of Presentation
      Kanazawa
    • Year and Date
      2010-06-25
    • Data Source
      KAKENHI-PUBLICLY-22020009
  • [Presentation] Discovery of AtgS/Atg7-independent alternative macroautophagy2010

    • Author(s)
      S.Shimizu
    • Organizer
      6^<th> Institute network symposium
    • Place of Presentation
      Kanazawa
    • Year and Date
      2010-06-25
    • Data Source
      KAKENHI-PROJECT-22229002
  • [Presentation] A critical role for the autophagy gene Ulkl in Atg5- independent alternative macroautophagy2010

    • Author(s)
      S.Shimizu
    • Organizer
      Gordon Conference
    • Place of Presentation
      Lucca, Italy
    • Year and Date
      2010-04-25
    • Data Source
      KAKENHI-PUBLICLY-22020009
  • [Presentation] Multiple mechanisms of cell death and their regulation by mitochondria2010

    • Author(s)
      S.Shimizu
    • Organizer
      第74回日本循環器学会
    • Place of Presentation
      京都
    • Year and Date
      2010-03-05
    • Data Source
      KAKENHI-PROJECT-21659076
  • [Presentation] Discovery of AtgS/Atg7-independent alternative macroautophagy2010

    • Author(s)
      S.Shimizu
    • Organizer
      6^<th> Institute network symposium
    • Place of Presentation
      Kanazawa
    • Year and Date
      2010-06-25
    • Data Source
      KAKENHI-PROJECT-21659076
  • [Presentation] 1. Multiple mechanisms of cell death and their regulationby Bcl-22008

    • Author(s)
      Shigeomi Shimizu
    • Organizer
      JAACT2008
    • Place of Presentation
      Fukuoka
    • Year and Date
      2008-11-25
    • Data Source
      KAKENHI-PROJECT-19659349
  • [Presentation] MITOCHONDRIA and NON-APOPTOTIC CELL DEATH.2007

    • Author(s)
      Shimizu S
    • Organizer
      4th Annual Meeting of Asian Society for Mitochondrial Research and Medicine,
    • Place of Presentation
      Seoul
    • Data Source
      KAKENHI-PROJECT-18023024
  • [Presentation] Physiological Role of Atg5-independent macroautophagy

    • Author(s)
      Shimizu S
    • Organizer
      The 16th Northeastern Asian Symposium
    • Place of Presentation
      Busan, Korea
    • Year and Date
      2014-12-19 – 2014-12-20
    • Invited
    • Data Source
      KAKENHI-PROJECT-25670139
  • [Presentation] Development of Molecularly Targeted Anticancer Agents Based on the Regulation of Autophagic Cell Death

    • Author(s)
      Shimizu S
    • Organizer
      The Uehara Memorial Foundation Symposium 2014
    • Place of Presentation
      Tokyo, Japan
    • Year and Date
      2014-06-15 – 2014-06-17
    • Invited
    • Data Source
      KAKENHI-PROJECT-22229002
  • [Presentation] Development of Molecularly Targeted Anticancer Agents Based on the Regulation of Autophagic Cell Death

    • Author(s)
      Shimizu S
    • Organizer
      The Uehara Memorial Foundation Symposium 2014
    • Place of Presentation
      Tokyo, Japan
    • Year and Date
      2014-06-15 – 2014-06-17
    • Invited
    • Data Source
      KAKENHI-PROJECT-25670139
  • [Presentation] Physiological Role of Atg5-independent macroautophagy

    • Author(s)
      Shimizu S
    • Organizer
      The 16th Northeastern Asian Symposium
    • Place of Presentation
      Busan, Korea
    • Year and Date
      2014-12-19 – 2014-12-20
    • Invited
    • Data Source
      KAKENHI-PROJECT-22229002
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  • 78.  木下 正弘
    # of Collaborated Projects: 0 results
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  • 79.  有田 誠
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  • 80.  有田 正規
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    # of Collaborated Products: 1 results
  • 81.  どど 孝介
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  • 82.  袖岡 幹子
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  • 83.  巽 智秀
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  • 84.  竹原 徹郎
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