SHIMIZU Shigeomi 清水重臣

Researcher Number	70271020
Other IDs	https://orcid.org/0000-0002-8437-0791
External Links
Affiliation (Current)	2019: 東京医科歯科大学, 難治疾患研究所, 教授
Affiliation (based on the past Project Information) *help	2006 – 2019: Tokyo Medical and Dental University, Medical Research Institute, Professor, 難治疾患研究所, 教授 1999 – 2005: Osaka University Graduate School of Medicine, Assistant Professor, 医学系研究科, 助教授 2002: 大阪大学, 医学研究科, 助教授 1996 – 1998: Osaka University Medical School, Assistant Professor, 医学部, 助手
Review Section/Research Field	Principal Investigator Biological Sciences / Pathological medical chemistry / Complex systems / Functional biochemistry / General medical chemistry / Digestive surgery / Cell biology / Pathological medical chemistry Except Principal Investigator General surgery / Digestive surgery … More
Keywords	Principal Investigator ミトコンドリア / アポトーシス / Bcl-2 / オートファジー / 神経変性疾患 / Bax / シグナル伝達 / 生体分子 / ストレス / 発癌 … More Except Principal Investigator アポトーシス / ミトコンドリア / bcl-2 / Bcl-2 / apoptosis / オートファジー / ICE / mitochondria / p53 / VEGF / HIF-1 / hypoxia / アデノウイルスベクター / CTLA4-Ig / Fas Ligand / CTLA4Ig / FK506 / 炎症性腸疾患 / Th1 / 無酸素障害 / necrosis / CPP-32 / 核 / プログラム細胞死 / カスペース / シトクロムc / DNA傷害 / Acinus / Becline / APG5 / ナノバブル水 / 虚血再灌流傷害 / 心筋虚血 / 心筋保護 / 凍結保存 / Bc1-2 / caspase / dominant negative / 膵・膵島移植 / HVJリポソーム / Fas ligand / インスリン依存型糖尿病(IDDM) / BBラット / NKT細胞 / インスリン依存型糖尿病 / 膵島移植 / islet / BB-rat / IDDM / NKT cells / 膵島 / CTL4Ig / Islet / adenoviral vector / IL-10ノックアウトマウス / Bcl-2トランスジェニックマウス / 腸管上皮 / IL-10^<- / ->マウス / 消化管上皮 / Inflammatory Bowel Disease / IL-10 knock out mouse / Bcl transgenic mouse / Intestinal epithelium / 動脈硬化 / 平滑筋細胞 / Bcl-2ファミリー / PTP / Apoptosis / Atherosclerosis / Smooth muscle cell Less

Atg5非依存的オートファジー誘導活性化合物のマウス腸炎モデルに対する効果の検討Ongoing
- Principal Investigator
  
  松田宙
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Osaka University
Regulation of brain aging by alternative autophagyPrincipal Investigator
- Principal Investigator
  
  清水重臣
- Project Period (FY)
  2017
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
Analysis of "Response zone" and " Communication zone" in mitochondria and Golgi apparatusPrincipal InvestigatorOngoing
- Principal Investigator
  
  清水重臣
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
Toward an integrative understanding of functional zones in organellesArea Organizer
- Area Organizer
  
  清水重臣
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
Toward an integrative understanding of functional zones in organellesPrincipal InvestigatorOngoing
- Principal Investigator
  
  清水重臣
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
Biological roles of novel proteolytic mechanism GOMEDPrincipal InvestigatorOngoing
- Principal Investigator
  
  清水重臣
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General medical chemistry
- Research Institution
  Tokyo Medical and Dental University
Development of small compounds that induce alternative autophagyPrincipal Investigator
- Principal Investigator
  
  SHIMIZU Shigeomi
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tokyo Medical and Dental University
新規オートファジーによる脳老化タンパク質調節機構の解析と創薬開発研究Principal Investigator
- Principal Investigator
  
  清水重臣
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
Development of autophagy visualization tools and analyses of physiological roles of autophagyPrincipal Investigator
- Principal Investigator
  
  SHIMIZU Shigeomi
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  Tokyo Medical and Dental University
ミトコンドリア膜上に一過性に形成される過渡的細胞死孔の捕捉Principal Investigator
- Principal Investigator
  
  清水重臣
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Tokyo Medical and Dental University
Structural analysis of mitochondrial apoptotic porePrincipal Investigator
- Principal Investigator
  
  SHIMIZU Shigeomi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Functional biochemistry
- Research Institution
  Tokyo Medical and Dental University
新しく発見したオートファジー機構を介した蛋白質品質管理システムの解析Principal Investigator
- Principal Investigator
  
  清水重臣
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
ミトコンドリア膜上に一過性に形成される過渡期細胞死孔の捕捉Principal Investigator
- Principal Investigator
  
  清水重臣
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Tokyo Medical and Dental University
Studies of alternative macroautophagy and its application for "Autophagic Diseases"Principal Investigator
- Principal Investigator
  
  SHIMIZU Shigeomi
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tokyo Medical and Dental University
新しく発見したオートファジーを基盤とした細胞内浄化システムの包括的理解Principal Investigator
- Principal Investigator
  
  清水重臣
- Project Period (FY)
  2010
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tokyo Medical and Dental University
アポトーシスを可視化するマウスの開発とその応用Principal Investigator
- Principal Investigator
  
  清水重臣
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tokyo Medical and Dental University
酸素ナノバブル水の細胞機能保護効果の解明、特に心臓保存への応用に関する研究Principal Investigator
- Principal Investigator
  
  清水重臣, 田中啓之
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Thoracic surgery
- Research Institution
  Tokyo Medical and Dental University
ミトコンドリアストレスを介した神経変性疾患の分子機構解明とその治療Principal Investigator
- Principal Investigator
  
  清水重臣
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
ミトコンドリアストレスを介した神経変性疾患の分子機構解明とその治療Principal Investigator
- Principal Investigator
  
  清水重臣
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
発癌におけるオートファジー様細胞死の役割とそれを応用した分子標的治療法の開発
- Principal Investigator
  
  長谷川順一
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Osaka University
Analysis of biological role and molecular mechanisms of autophagic cell deathPrincipal Investigator
- Principal Investigator
  
  SHIMIZU Shigeomi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tokyo Medical and Dental University
  Osaka University
ミトコンドリア膜透過性亢進機構を標的とした抗アポトーシス薬の開発Principal Investigator
- Principal Investigator
  
  清水重臣
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Regulation of Intestinal Mucosal Immunity in a Mouse Model on Inflammatory Bowel Disease
- Principal Investigator
  
  ITO Toshinori
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Osaka University
Study of the molecular mechanism and clinical implication of a novel apoptosis gene
- Principal Investigator
  
  YASUDA Osamu
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  細胞死(アポトーシス)
- Research Institution
  Osaka University
ミトコンドリア膜透過性亢進機構を標的とした抗アポトーシス薬の開発Principal Investigator
- Principal Investigator
  
  清水重臣
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
アポトーシスにおけるミトコンドリア膜透過性亢進因子の同定とその分子機構の解明Principal Investigator
- Principal Investigator
  
  清水重臣
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Development of anti-and pro-apoptotic drugs via regulation of VDAC, a mitochondrial outermembrane proteinPrincipal Investigator
- Principal Investigator
  
  SHIMIZU Shigeomi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Osaka University
アポトーシスにおけるミトコンドリア膜透過性亢進因子の同定とその分子機構の解明Principal Investigator
- Principal Investigator
  
  清水重臣
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Research for immuno-logical tolerance induction in islet xeno-transplantation -Therapeutic effect of a adenovirus or retrovirus mediated CTLA4Ig gene transfer combined with immunosuppressive regents-
- Principal Investigator
  
  NAKATA Seizou
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Osaka University
Identification of novel cytochrome c releasing factor and analysis of its molecular function on apoptosisPrincipal Investigator
- Principal Investigator
  
  SHIMIZU Shigeomi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  Osaka University
アポトーシスにおける細胞質から核への情報伝達メカニズム
- Principal Investigator
  
  辻本賀英
- Project Period (FY)
  1999 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
The induction of a donor-specific tolerance in islet xenotransplantation models by Bcl-2/Fas ligand transfection combined with immunosuppressive agents .
- Principal Investigator
  
  NAKATA Seizou
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Osaka University
Development of novel cancer gene therapy using HIF-1 gene
- Principal Investigator
  
  YUMIBA Takeyoshi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Osaka University
Study of molecular basis of apoptosis using in vitro system
- Principal Investigator
  
  TSUJIMONOTO Yoshihide
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  Molecular biology
- Research Institution
  Osaka University
Novel cancer gene therapy using apoptosis-related genePrincipal Investigator
- Principal Investigator
  
  SHIMIZU Shigeomi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Osaka University
肝虚血障害機構の遺伝学的解明と細胞死抑制遺伝子bc1−2導入による保護
- Principal Investigator
  
  上池渉
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Osaka University
STUDY OF APOPTOSIS IN VITRO CELL-FREE SYSTEM
- Principal Investigator
  
  TSUJIMOTO Yoshihide
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Osaka University Medical School

[Book] Innovative Medicine : Basic Research and Development2015
- Author(s)
  Shimizu S
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-25670139
[Book] Innovative Medicine : Basic Research and Development2015
- Author(s)
  Shimizu S
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-22229002
[Book] Innovative Medicine : Basic Research and Development2015
- Author(s)
  shimizu S
- Total Pages
  339
- Publisher
  Springer Press
- Data Source
  KAKENHI-PUBLICLY-15H01554
[Book] AUTOPHAGY: Cancer, Other Pathologies, Inflammation, Immunity, and Infection.Vol. 22014
- Author(s)
  S. Shimizu, S. Arakawa, Y. Nishida, H. Yamaguchi, T. Yoshida.
- Total Pages
  250
- Publisher
  Academic Press,
- Data Source
  KAKENHI-PROJECT-22229002
[Book] AUTOPHAGY: Cancer, Other Pathologies, Inflammation, Immunity, and Infection.Vol. 22014
- Author(s)
  S. Shimizu, S. Arakawa, Y. Nishida, H. Yamaguchi, T. Yoshida.
- Total Pages
  250
- Publisher
  Academic Press,
- Data Source
  KAKENHI-PUBLICLY-24121708
[Book] AUTOPHAGY: Cancer, Other Pathologies, Inflammation, Immunity, and Infection.Vol. 22014
- Author(s)
  Shimizu S, Arakawa S, Nishida Y, Yamaguchi H, Yoshida T
- Total Pages
  250
- Publisher
  Academic Press
- Data Source
  KAKENHI-PROJECT-25670139
[Book] アポトーシス調節系「分子標的薬」日本臨床2012
- Author(s)
  清水重臣
- Data Source
  KAKENHI-PROJECT-23657084
[Book] 細胞死解析プロトコール2011
- Author(s)
  清水重臣
- Total Pages
  223
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-22229002
[Book] 細胞死解析プロトコール2011
- Author(s)
  清水重臣
- Total Pages
  223
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-23657084
[Book] 細胞死解析プロトコール2011
- Author(s)
  清水重臣
- Total Pages
  223
- Publisher
  羊土社
- Data Source
  KAKENHI-PUBLICLY-22121505
[Book] 細胞死解析プロトコール2011
- Author(s)
  清水重臣
- Total Pages
  223
- Publisher
  羊土社
- Data Source
  KAKENHI-PUBLICLY-22020009
[Book] からだと酸素の事典2009
- Author(s)
  清水重臣
- Publisher
  朝倉書店(印刷中)
- Data Source
  KAKENHI-PROJECT-19659349
[Book] 神経変性疾患のサイエンス2007
- Author(s)
  清水重臣
- Total Pages
  247
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-18023024
[Book] 細胞死・アポトーシス集中マスター2005
- Author(s)
  清水重臣
- Total Pages
  130
- Publisher
  羊土社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390094
[Book] Mammalian autophagy can occur through an Atg5/Atg7- independent pathway. AUTOPHAGY: Cancer, Other Pathologies
- Author(s)
  S. Shimizu, S. Arakawa, Y. Nishida, H. Yamaguchi, T. Yoshida
- Publisher
  Inflammation, Immunity, and Infection(印刷中)
- Data Source
  KAKENHI-PROJECT-23657084
[Journal Article] Ligand Binding to Human Prostaglandin E Receptor EP4 at the Lipid-Bilayer Interface2019
- Author(s)
  Toyoda Y, Morimoto K, Suno R, et al.
- Journal Title
  
  Journal of Chemical Physics
  
  Volume: 15 Pages: 18-26
- DOI
  10.1038/s41589-018-0131-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05334, KAKENHI-PROJECT-18K14904, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05905, KAKENHI-PLANNED-17H06414, KAKENHI-PROJECT-17H01531, KAKENHI-PROJECT-17H03663, KAKENHI-PROJECT-17H03990
[Journal Article] Role of cyclooxygenase-2/prostaglandin E2/prostaglandin E receptor 4 signaling in cardiac reprogramming.2019
- Author(s)
  Muraoka Naoto、Nara Kaori、Tamura Fumiya、Kojima Hidenori、Yamakawa Hiroyuki、Sadahiro Taketaro、Miyamoto Kazutaka、Isomi Mari、Haginiwa Sho、Tani Hidenori、Kurotsu Shota、Osakabe Rina、Torii Satoru、Shimizu Shigeomi、Okano Hideyuki、Sugimoto Yukihiko、Fukuda Keiichi、Ieda Masaki
- Journal Title
  
  Nat Commun
  
  Volume: 10 Pages: 1-15
- DOI
  10.1038/s41467-019-08626-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06210, KAKENHI-PROJECT-18K08047, KAKENHI-PROJECT-18K08114, KAKENHI-PROJECT-17K16024, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05905, KAKENHI-PLANNED-17H06414, KAKENHI-PROJECT-17H01533, KAKENHI-PROJECT-17H03990, KAKENHI-PROJECT-17J06637, KAKENHI-PROJECT-18J21479, KAKENHI-PROJECT-15K09147, KAKENHI-PROJECT-16K19426
[Journal Article] Beclin 1 regulates recycling endosome and is required for skin development in mice.2019
- Author(s)
  Noguchi Saori、Honda Shinya、Saitoh Tatsuya、Matsumura Hiroyuki、Nishimura Emi、Akira Shizuo、Shimizu Shigeomi
- Journal Title
  
  Commun Biol.
  
  Volume: 2 Pages: 37-37
- DOI
  10.1038/s42003-018-0279-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0229, KAKENHI-PUBLICLY-17H05614, KAKENHI-ORGANIZER-17H06413, KAKENHI-PLANNED-17H06414, KAKENHI-PLANNED-17H06415, KAKENHI-PROJECT-17H01533, KAKENHI-PROJECT-17K19514, KAKENHI-PROJECT-17K15613
[Journal Article] Prediction of intracellular targets of a small compound by analyzing peptides presented on MHC class I.2019
- Author(s)
  Sugimoto Yuna、Murohashi Michiko、Arakawa Satoko、Honda Shinya、Shimizu Shigeomi
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 508 Pages: 480-486
- DOI
  10.1016/j.bbrc.2018.11.089
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06414, KAKENHI-PROJECT-17H01533, KAKENHI-PROJECT-17K15613
[Journal Article] Organelle zones in mitochondria2018
- Author(s)
  Shimizu Shigeomi
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 165 Pages: 101-107
- DOI
  10.1093/jb/mvy068
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06414, KAKENHI-PROJECT-17H01533
[Journal Article] Association between autophagy and neurodegenerative diseases2018
- Author(s)
  Fujikake N, Shin M, Shimizu S
- Journal Title
  
  Frontiers Neuroscience
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15230
[Journal Article] Association Between Autophagy and Neurodegenerative Diseases2018
- Author(s)
  Nobuhiro Fujikake, Minkyoung Shin, Shigeomi Shimizu*
- Journal Title
  
  Frontiers in Neuroscience
  
  Volume: 12 Pages: 255-255
- DOI
  10.3389/fnins.2018.00255
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15360, KAKENHI-PLANNED-17H06414, KAKENHI-PROJECT-17H01533
[Journal Article] Small fluorescent molecules for monitoring autophagic flux2018
- Author(s)
  Iwashita Hidefumi、Sakurai Hajime Tajima、Nagahora Noriyoshi、Ishiyama Munetaka、Shioji Kosei、Sasamoto Kazumi、Okuma Kentaro、Shimizu Shigeomi、Ueno Yuichiro
- Journal Title
  
  FEBS Letters
  
  Volume: 592 Pages: 559-567
- DOI
  10.1002/1873-3468.12979
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06414, KAKENHI-ORGANIZER-17H06413, KAKENHI-PROJECT-17H01533
[Journal Article] Biological Roles of Alternative Autophagy2018
- Author(s)
  Shigeomi Shimizu
- Journal Title
  
  Mol. Cells
  
  Volume: 41 Pages: 50-54
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06414, KAKENHI-ORGANIZER-17H06413
[Journal Article] Dram1 regulates DNA damage-induced alternative autophagy2018
- Author(s)
  Nagata M, Arakawa S, Yamaguchi H, Torii S, Endo H, Tsujioka M, Honda S, Nishida Y, Konishi A, Shimizu S
- Journal Title
  
  Cell stress
  
  Volume: 2 Pages: 55-65
- DOI
  10.15698/cst2018.03.127
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08649, KAKENHI-PLANNED-17H06414, KAKENHI-PLANNED-26110005, KAKENHI-PROJECT-15K08420, KAKENHI-PROJECT-16K15230, KAKENHI-PROJECT-17K15448, KAKENHI-ORGANIZER-17H06413, KAKENHI-PROJECT-17H01533
[Journal Article] Role of Atg5-dependent cell death in the embryonic development of Bax/Bak double-knockout mice2017
- Author(s)
  Arakawa S, Tsujioka M, Yoshida T, Tajima-Sakurai H, Nishida Y, Matsuoka Y, Yoshino I, Tsujimoto Y, Shimizu S.
- Journal Title
  
  Cell Death & Differentiation
  
  Volume: 9 Pages: 1598-1608
- DOI
  10.1038/cdd.2017.84
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-17H05691, KAKENHI-PLANNED-17H06414, KAKENHI-PLANNED-26110005, KAKENHI-PROJECT-15K08420, KAKENHI-ORGANIZER-17H06413, KAKENHI-PROJECT-17H01533
[Journal Article] Identification of an atypical monocyte and committed progenitor involved in fibrosis.2017
- Author(s)
  Kozaki T, Komano J, Kanbayashi D, Takahama M, Misawa T, Satoh T, Takeuchi O, Kawai T, Shimizu S, Matsuura Y, Akira S, Saitoh T
- Journal Title
  
  PNAS
  
  Volume: 114 Pages: 96-101
- DOI
  10.1073/pnas.1621508114
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01380, KAKENHI-PUBLICLY-15H01381, KAKENHI-PUBLICLY-15H01554, KAKENHI-PROJECT-16H06234, KAKENHI-PROJECT-26293107, KAKENHI-PROJECT-26713005, KAKENHI-PROJECT-26860453, KAKENHI-PROJECT-16K15230, KAKENHI-PROJECT-17K19559, KAKENHI-PUBLICLY-17H05691, KAKENHI-PROJECT-17H04066
[Journal Article] Rhodium-catalyzed odorless synthesis of diaryl sulfides from borylarenes and S-aryl thiosulfonates2017
- Author(s)
  Kanemoto Kazuya、Sugimura Yasuyuki、Shimizu Shigeomi、Yoshida Suguru、Hosoya Takamitsu
- Journal Title
  
  Chem. Commun.
  
  Volume: 53 Pages: 10640-10643
- DOI
  10.1039/c7cc05868c
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-16H01133, KAKENHI-PROJECT-15H03118, KAKENHI-PROJECT-17H01533
[Journal Article] Intrinsic Autophagy Is Required for the Maintenance of Intestinal Stem Cells and for Irradiation-Induced Intestinal Regeneration.2017
- Author(s)
  Asano J, Sato T, Ichinose S, Kajita M, Onai N, Shimizu S, Ohteki T.
- Journal Title
  
  Cell Reports
  
  Volume: 20 Pages: 1050-1060
- DOI
  10.1016/j.celrep.2017.07.019
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-17H05691, KAKENHI-PROJECT-15H04717, KAKENHI-PROJECT-16K19571, KAKENHI-PROJECT-17H01533
[Journal Article] Molecular mechanisms and physiological roles of Atg5/Atg7-independent alternative autophagy2017
- Author(s)
  Arakawa S, Honda S, Yamaguchi H, Shimizu S.
- Journal Title
  
  Proc. Jpn. Acad., Ser. B
  
  Volume: 93(6) Issue: 6 Pages: 378-385
- DOI
  10.2183/pjab.93.023
- NAID
  130005696809
- ISSN
  0386-2208, 1349-2896
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-17K15613, KAKENHI-PUBLICLY-17H05691, KAKENHI-PLANNED-26110005
[Journal Article] Hyperoxidation of ether-linked phospholipids accelerates neutrophil extracellular trap formation.2017
- Author(s)
  Yotsumoto Satoshi、Muroi Yuito、Chiba Tatsuya、Ohmura Rio、Yoneyama Maki、Magarisawa Megumi、Dodo Kosuke、Terayama Naoki、Sodeoka Mikiko、Aoyagi Ryohei、Arita Makoto、Arakawa Satoko、Shimizu Shigeomi、Tanaka Masato
- Journal Title
  
  Journal, Scientific Reports
  
  Volume: 7 Pages: 16026-16026
- DOI
  10.1038/s41598-017-15668-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05898, KAKENHI-PLANNED-26110004, KAKENHI-PLANNED-26110005, KAKENHI-PLANNED-26110006, KAKENHI-PROJECT-15H04648, KAKENHI-PROJECT-17H04068, KAKENHI-PROJECT-15K08420, KAKENHI-PROJECT-17H01533
[Journal Article] Live Cell Imaging of Mitochondrial Autophagy with a Novel Fluorescent Small Molecule2017
- Author(s)
  Iwashita Hidefumi、Torii Satoru、Nagahora Noriyoshi、Ishiyama Munetaka、Shioji Kosei、Sasamoto Kazumi、Shimizu Shigeomi、Okuma Kentaro
- Journal Title
  
  ACS Chemical Biology
  
  Volume: 12 Pages: 2546-2551
- DOI
  10.1021/acschembio.7b00647
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H01533
[Journal Article] Golgi membrane‐associated degradation pathway in yeast and mammals2016
- Author(s)
  H. Yamaguchi, S. Arakawa, T. Kanaseki, T. Miyatsuka, Y. Fujitani, H. Watada, Y. Tsujimoto, S. Shimizu
- Journal Title
  
  EMBO J
  
  Volume: 35 Pages: 1991-2007
- DOI
  10.15252/embj.201593191
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-15H01554, KAKENHI-PLANNED-26110005, KAKENHI-PROJECT-15K14519, KAKENHI-PROJECT-15K18860, KAKENHI-PROJECT-15K08420, KAKENHI-PROJECT-16K15230
[Journal Article] Identification of PPM1D as an essential Ulk1 phosphatase for genotoxic stress-induced autophagy2016
- Author(s)
  S. Torii, T. Yoshida, S. Arakawa, S. Honda, A. Nakanishi, S. Shimizu
- Journal Title
  
  EMBO R
  
  Volume: 11 Pages: 1552-1564
- DOI
  10.15252/embr.201642565
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-15H01554, KAKENHI-PLANNED-26110005, KAKENHI-PROJECT-15K08420, KAKENHI-PROJECT-16K15230
[Journal Article] Autophagy suppresses cell migration by degrading GEF-H1, a RhoA GEF.2016
- Author(s)
  T. Yoshida, M. Tsujioka, S. Honda, S. Shimizu
- Journal Title
  
  OncoTarget
  
  Volume: 7 Pages: 34420-34429
- DOI
  10.18632/oncotarget.8883
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01554, KAKENHI-PLANNED-26110006, KAKENHI-PROJECT-26293089, KAKENHI-PROJECT-15K19004, KAKENHI-PROJECT-16K15230
[Journal Article] Ulk1-mediated Atg5-independent macroautophagy mediates elimination of mitochondria from embryonic reticulocytes.2016
- Author(s)
  Watanabe Y, Honda S, Konishi A, Satoko Arakawa S, Murohashi M, Yamaguchi H, Torii S, Tanabe M, Tanaka S, Warabi E, Shimizu S.
- Journal Title
  
  Nat Commun13508
  
  Volume: 7 Pages: 1-12
- DOI
  10.1038/ncomms13508
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01484, KAKENHI-PUBLICLY-15H01554, KAKENHI-PLANNED-26110005, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-16H02670, KAKENHI-PROJECT-15H04926, KAKENHI-PROJECT-25440080, KAKENHI-PROJECT-26430051, KAKENHI-PROJECT-26460485, KAKENHI-PROJECT-15K15491, KAKENHI-PROJECT-15K19004, KAKENHI-PROJECT-15K08420, KAKENHI-PROJECT-16K15230
[Journal Article] TRF2 Interacts with Core Histones to Stabilize Chromosome Ends2016
- Author(s)
  Konishi A, Izumi T, Shimizu S
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 291(39) Pages: 20798-810
- DOI
  10.1074/jbc.m116.719021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25440080, KAKENHI-PROJECT-16K15230
[Journal Article] Optogenetic activation of axon guidance receptors controls direction of neurite outgrowth.2016
- Author(s)
  Y. Nasu, A. Benke, S. Arakawa, G. Yoshida, G. Kawamura, S. Manley, S. Shimizu, T. Ozawa
- Journal Title
  
  Sci. Rep.
  
  Volume: 6 Pages: 23976-23976
- DOI
  10.1038/srep27505
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01554, KAKENHI-PLANNED-26110005, KAKENHI-PROJECT-15J02898, KAKENHI-PROJECT-15K08420, KAKENHI-PROJECT-16K14016, KAKENHI-PROJECT-16K15230, KAKENHI-PROJECT-16K19103, KAKENHI-PROJECT-26220805
[Journal Article] Identification of a novel compound that inhibits both mitochondria-mediated necrosis and apoptosis.2015
- Author(s)
  S. Arakawa, I. Nakanomyo, Y. Kudo-Sakamoto, H. Akazawa, I. Komuro, S. Shimizu.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 467 Pages: 1006-11
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-15H01554
[Journal Article] Direct Thioamination of Arynes via Reaction with Sulfilimines and Migratory N-Arylation.2015
- Author(s)
  Suguru Yoshida, Takahisa Yano, Yoshihiro Misawa, Yasuyuki Sugimura, Kazunobu Igawa, Shigeomi Shimizu, Katsuhiko Tomooka, Takamitsu Hosoya
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 137 Pages: 14071-14074
- DOI
  10.1021/jacs.5b10557
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26350971, KAKENHI-PUBLICLY-15H01554, KAKENHI-PROJECT-15H03118
[Journal Article] A mild and facile synthesis of aryl and alkenyl sulfides via copper-catalyzed deborylthiolation of organoborons with thiosulfonates.2015
- Author(s)
  Suguru Yoshida, Yasuyuki Sugimura, Yuki Hazama, Yoshitake Nishiyama, Takahisa Yano, Shigeomi Shimizu, Takamitsu Hosoya
- Journal Title
  
  Chemical Commun
  
  Volume: 51 Pages: 16613-16
- DOI
  10.1039/c5cc07463k
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26350971, KAKENHI-PUBLICLY-15H01554, KAKENHI-PROJECT-15H03118
[Journal Article] Ulk1-mediated Atg5-independent macroautophagy mediates elimination of mitochondria from embryonic reticulocytes.2014
- Author(s)
  S. Honda, S. Arakawa, Y. Nishida, H. Yamaguchi, E. Ishii, S. Shimizu,
- Journal Title
  
  Nature Communications
  
  Volume: press
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24121708
[Journal Article] Ulk1-mediated Atg5-independent macroautophagy mediates elimination of mitochondria from embryonic reticulocytes.2014
- Author(s)
  S. Honda, S. Arakawa, Y. Nishida, H. Yamaguchi, E. Ishii, S. Shimizu,
- Journal Title
  
  Nature Communications
  
  Volume: press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22229002
[Journal Article] Ulk1-mediated Atg5-independent macroautophagy mediates elimination of mitochondria from embryonic reticulocytes2014
- Author(s)
  S. Honda, S. Arakawa, Y. Nishida, H. Yamaguchi, E. Ishii, S. Shimizu.
- Journal Title
  
  Nat Commun
  
  Volume: 5 Pages: 4004-4004
- DOI
  10.1038/ncomms5004
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-22229002, KAKENHI-PROJECT-24659178, KAKENHI-PROJECT-24689020, KAKENHI-PROJECT-25670139, KAKENHI-PROJECT-26670503
[Journal Article] Autophagic cell death and cancer.2014
- Author(s)
  S. Shimizu, T. Yoshida, M. Tsujioka, S. Arakawa.
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 15 Pages: 3145-3153
- DOI
  10.3390/ijms15023145
- NAID
  40019721683
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-22229002, KAKENHI-PUBLICLY-24121708, KAKENHI-PROJECT-24659178, KAKENHI-PROJECT-24689020, KAKENHI-PUBLICLY-25113509, KAKENHI-PROJECT-25670139
[Journal Article] Ulk1-mediated Atg5-independent macroautophagy mediates elimination of mitochondria from embryonic reticulocytes.2014
- Author(s)
  Honda S, Arakawa S, Nishida Y, Yamaguchi H, Ishii E, Shimizu S,
- Journal Title
  
  Nature Commun
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670139
[Journal Article] Alternative macroautophagy and mitophagy.2014
- Author(s)
  S. Shimizu, S. Honda, S. Arakawa, H. Yamaguchi
- Journal Title
  
  Int J Biochem Cell Biol.
  
  Volume: 50 Pages: 3145-3153
- DOI
  10.1016/j.biocel.2014.02.016
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-22229002, KAKENHI-PUBLICLY-24121708, KAKENHI-PROJECT-24659178, KAKENHI-PROJECT-24689020, KAKENHI-PUBLICLY-25113509, KAKENHI-PROJECT-25670139
[Journal Article] Inhibition of epithelial cell death by Bcl-2 improved chronic colitis in IL10 KO mice.2013
- Author(s)
  T. Mizushima, S. Arakawa, Y. Sanada, I. Yoshino, D. Miyazaki, H. Urushima, Y. Tsujimoto, T. Ito, S. Shimizu
- Journal Title
  
  Am. J. Pathol.
  
  Volume: 183 Pages: 1936-1944
- DOI
  10.1016/j.ajpath.2013.08.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22229002, KAKENHI-PUBLICLY-24121708, KAKENHI-PROJECT-24659178, KAKENHI-PROJECT-24689020, KAKENHI-PUBLICLY-25113509, KAKENHI-PUBLICLY-25131710, KAKENHI-PROJECT-25650078, KAKENHI-PROJECT-25670139
[Journal Article] オートファジー細胞死の分子機構とその生体での役割2012
- Author(s)
  清水重臣
- Journal Title
  
  「実験医学」羊土社
  
  Volume: 30 Pages: 550-5
- Data Source
  KAKENHI-PROJECT-23657084
[Journal Article] Involvement of Beclin 1 in the engulfment of apoptotic cells2012
- Author(s)
  A. Konishi, S. Arakawa, Z. Yue, S.Shimizu
- Journal Title
  
  J. Biol. Chem
  
  Volume: 287 Pages: 13919-29
- Data Source
  KAKENHI-PROJECT-23657084
[Journal Article] 生体におけるマイトファジーの役割2012
- Author(s)
  清水重臣
- Journal Title
  
  「実験医学」羊土社
  
  Volume: 30 Pages: 1390-95
- Data Source
  KAKENHI-PROJECT-23657084
[Journal Article] Shigella targets epithelial tricellular junctions to spread between cells via a noncanonicalclathrin-dependent endocytic pathway2012
- Author(s)
  M. Fukamatsu, M. Ogawa, S. Arakawa, H.Ashida, M. Suzuki, M. Furuse, K. Nakayama, S. Shimizu, M. Kin, H. Mimuro, C. Sasakawa
- Journal Title
  
  Cell Host Microbe
  
  Volume: 11 Pages: 325-336
- Data Source
  KAKENHI-PROJECT-23657084
[Journal Article] Transformation of an antimicrobial peptide into a plasma membrane- permeable,mitochondria-targeted peptide via the substitution of lysine with arginine2012
- Author(s)
  I. Nakase, S. Okumura, S. Katayama, H. Hirose, S. Pujals, H. Yamaguchi, S. Arakawa, S. Shimizu, S. Futaki
- Journal Title
  
  Chemical Communication
  
  Volume: 48 Pages: 11097-99
- Data Source
  KAKENHI-PROJECT-23657084
[Journal Article] Inhibits Vascular Endothelial Growth Factor Expression in Solid Tumor2012
- Author(s)
  Y. Yoshioka, S. Shimizu, T. Ito, M.Taniguchi, M. Nomura, T. Nishida, Y. Sawa.
- Journal Title
  
  J Surg Res
  
  Volume: 174 Pages: 291-297
- Data Source
  KAKENHI-PROJECT-23657084
[Journal Article] Hypertrophy and unconventional cell division of hepatocytes underlie liver regeneration2012
- Author(s)
  Y. Miyaoka, K. Ebato, H. Kato, S. Arakawa, S. Shimizu, A. Miyajima
- Journal Title
  
  Curr. Biol
  
  Volume: 22 Pages: 1166-75
- Data Source
  KAKENHI-PROJECT-23657084
[Journal Article] Stress-activated protein kinase MKK7 regulates axon elongation in thedeveloping cerebral cortex2011
- Author(s)
  T. Yamasaki, H. Kawasaki, S. Arakawa, K. Shimizu, S. Shimizu, O. Reiner, H. Okano, S. Nishina, N. Azuma, J.M. Penninger, T. Katada, H Nishina
- Journal Title
  
  Journal ofNeuroscience
  
  Volume: 31 Pages: 16872-16883
- Data Source
  KAKENHI-PROJECT-23657084
[Journal Article] Stress-activated protein kinase MKK7 regulates axon elongation in the developing cerebral cortex.2011
- Author(s)
  Tokiwa Yamasaki
- Journal Title
  
  Journal of Neuroscience
  
  Volume: 31 Pages: 16872-16883
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22020009, KAKENHI-PUBLICLY-22121505, KAKENHI-PROJECT-23657084
[Journal Article] Spatial coupling of mTOR and autophagy augments secretory phenotypes.2011
- Author(s)
  Masako Narita
- Journal Title
  
  Science
  
  Volume: 332 Pages: 966-970
- DOI
  10.1126/science.1205407
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22020009, KAKENHI-PUBLICLY-22121505, KAKENHI-PROJECT-22229002, KAKENHI-PROJECT-22770054, KAKENHI-PROJECT-23657084
[Journal Article] Delayed-onset caspase-dependent massive hepatocyte apoptosis upon Fas activation in Bak/Bax-deficient mice.2011
- Author(s)
  Hikita, H.
- Journal Title
  
  Hepatology
  
  Volume: VOL. 54 Pages: 240-251
- DOI
  10.1002/hep.24305
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0316, KAKENHI-PROJECT-21590841, KAKENHI-PROJECT-21659188, KAKENHI-PUBLICLY-22020009, KAKENHI-PUBLICLY-22121505, KAKENHI-PROJECT-22229002, KAKENHI-PROJECT-23657084
[Journal Article] Spatialcoupling of mTOR and autophagy augments secretory phenotypes2011
- Author(s)
  M. Narita, A.R.J. Young, S. Arakawa, S.A. Samarajiwa, T. Nakashima, S. Yoshida, S.K. Hong, L.S. Berry, S. Reichelt, M. Ferreira, S. Tavare, K. Inoki, S. Shimizu, M. Narita
- Journal Title
  
  Science
  
  Volume: 332 Pages: 966-970
- Data Source
  KAKENHI-PROJECT-23657084
[Journal Article] アポトーシスと非アポトーシス細胞死2011
- Author(s)
  清水重臣
- Journal Title
  
  「臨床血液」教育講演号
- NAID
  10029769484
- Data Source
  KAKENHI-PROJECT-23657084
[Journal Article] ミトコンドリアの変化2011
- Author(s)
  清水重臣
- Journal Title
  
  「細胞死解析プロトコール」羊土社
  
  Pages: 108-118
- Data Source
  KAKENHI-PROJECT-23657084
[Journal Article] Delayed-onset caspase-dependent massive hepatocyte apoptosis upon Fas activation in Bak/Bax-deficient mice2011
- Author(s)
  H. Hikita, T. Takehara, T. Kodama, S. Shimizu, M. Shigekawa, A. Hosui, T. Miyagi, T. Tatsumi, H. Ishida, Li W, T. Kanto, N. Hiramatsu, S. Shimizu, Y. Tsujimoto, N. Hayashi
- Journal Title
  
  Hepatology
  
  Volume: 54 Pages: 240-251
- Data Source
  KAKENHI-PROJECT-23657084
[Journal Article] Involvement of JNK in the regulation of autophagic cell death2010
- Author(s)
  S.Shimizu, et al.
- Journal Title
  
  Oncogene
  
  Volume: 29 Pages: 2070-2082
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22020009
[Journal Article] Involvement of JNK in the regulation of autophagic cell death2010
- Author(s)
  S.Shimizu, et al.
- Journal Title
  
  Oncogene
  
  Volume: 29 Pages: 2070-2082
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659076
[Journal Article] Autophagy takes an alternative pathway2010
- Author(s)
  S.Shimizu, et al.
- Journal Title
  
  Autophagy
  
  Volume: 6 Pages: 290-291
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22229002
[Journal Article] Autophagy takes an alternative pathway2010
- Author(s)
  S.Shimizu, et al.
- Journal Title
  
  Autophagy
  
  Volume: 6 Pages: 290-291
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659076
[Journal Article] Autophagy takes an alternative pathway2010
- Author(s)
  S.Shimizu, et al.
- Journal Title
  
  Autophagy
  
  Volume: 6 Pages: 290-291
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22121505
[Journal Article] Involvement of JNK in the regulation of autophagic cell death2010
- Author(s)
  S.Shimizu, et al.
- Journal Title
  
  Oncogene
  
  Volume: 29 Pages: 2070-2082
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22229002
[Journal Article] Involvement of JNK in the regulation of autophagic cell death.2010
- Author(s)
  S.Shimizu, et al
- Journal Title
  
  Oncogene (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659076
[Journal Article] Autophagy takes an alternative pathway2010
- Author(s)
  S.Shimizu, et al.
- Journal Title
  
  Autophagy
  
  Volume: 6 Pages: 290-291
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22020009
[Journal Article] Involvement of JNK in the regulation of autophagic cell death2010
- Author(s)
  S.Shimizu, et al.
- Journal Title
  
  Oncogene
  
  Volume: 29 Pages: 2070-2082
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22121505
[Journal Article] Role of the mitochondrial membrane permeability transition in cell death.2007
- Author(s)
  Tsujimoto Y & Shimizu S
- Journal Title
  
  Apoptosis 5
  
  Pages: 835-840
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18023024
[Journal Article] Furanonaphthoquinones cause apoptosis of cancer cells by inducing the production of reactive oxygen species by the mitochondrial voltage-dependent anion channel.2006
- Author(s)
  Simamura, E., Hirai, K., Shimada, H., Koyama, J., Niwa, Y., Shimizu, S.
- Journal Title
  
  Cancer Biology ＆ Therapy 5
  
  Pages: 11523-11523
- Data Source
  KAKENHI-PROJECT-18023024
[Journal Article] Mitochondrial membrane permeability transition and cell death.2006
- Author(s)
  Tsujimoto, Y., Nakagawa, T., Shimizu, S.
- Journal Title
  
  Biochim Biophys Acta. 9-10
  
  Pages: 1297-1297
- Data Source
  KAKENHI-PROJECT-17390094
[Journal Article] Antiapoptotic function of 17AA(+)WT1 (Wilms' tumor gene) isoforms on the intrinsic apoptosis pathway.2006
- Author(s)
  Ito, K., Oji, Y., Tatsumi, N., Shimizu, S., et al.
- Journal Title
  
  Oncogene 25
  
  Pages: 4217-4217
- Data Source
  KAKENHI-PROJECT-18023024
[Journal Article] Mitochondrial membrane permeability transition and cell death.2006
- Author(s)
  Tsujimoto, Y., Nakagawa, T., Shimizu, S.
- Journal Title
  
  Biochim Biophys Acta. 9-10
  
  Pages: 1297-1297
- Data Source
  KAKENHI-PROJECT-18023024
[Journal Article] Furanonaphthoquinones cause apoptosis of cancer cells by inducing the production of reactive oxygen species by the mitochondrial voltage-dependent anion channel.2006
- Author(s)
  Simamura, E., Hirai, K., Shimada, H., Koyama, J., Niwa, Y., Shimizu, S.
- Journal Title
  
  Cancer Biology ＆ Therapy 5
  
  Pages: 11523-11523
- Data Source
  KAKENHI-PROJECT-17390094
[Journal Article] Antiapoptotic function of 17AA(+)WT1 (Wilms' tumor gene) isoforms on the intrinsic apoptosis pathway.2006
- Author(s)
  Ito, K., Oji, Y., Tatsumi, N, Shimizu, S., et al.
- Journal Title
  
  Oncogene 25
  
  Pages: 4217-4217
- Data Source
  KAKENHI-PROJECT-17390094
[Journal Article] Chk2 regulates transcription-independent p53-mediated apoptosis in response to DNA damage.2005
- Author(s)
  Chen C, Shimizu S, et al.
- Journal Title
  
  Biochem Biophys Res Commun 333
  
  Pages: 427-431
- Data Source
  KAKENHI-PROJECT-17591331
[Journal Article] Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death.2005
- Author(s)
  T.Nakagawa, S.Shimizu, et al.
- Journal Title
  
  Nature 434
  
  Pages: 652-658
- Data Source
  KAKENHI-PROJECT-17390094
[Journal Article] Two distinct Fas-activated signaling pathways revealed by an antitumor drug D609.2005
- Author(s)
  Zhang L, Shimizu S, et al.
- Journal Title
  
  Oncogene. 24
  
  Pages: 2954-2962
- Data Source
  KAKENHI-PROJECT-17591331
[Journal Article] Chk2 regulates transcription-independent p53-mediated apoptosis in response to DNA damage2005
- Author(s)
  C.Chen, S.Shimizu, et al.
- Journal Title
  
  Biochem Biophys Res Commun. 333
  
  Pages: 427-431
- Data Source
  KAKENHI-PROJECT-17025025
[Journal Article] Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death.2005
- Author(s)
  Nakagawa T, Shimizu S, et al.
- Journal Title
  
  Nature. 434
  
  Pages: 652-658
- Data Source
  KAKENHI-PROJECT-17591331
[Journal Article] Chk2 regulates transcription-independent p53-mediated apoptosis in response to DNA damage2005
- Author(s)
  C.Chen, S.Shimizu, et al.
- Journal Title
  
  Biochem Biophys Res Commun. 333
  
  Pages: 427-431
- Data Source
  KAKENHI-PROJECT-17390094
[Journal Article] Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death.2005
- Author(s)
  T.Nakagawa, S.Shimizu, et al.
- Journal Title
  
  Nature 434
  
  Pages: 652-658
- Data Source
  KAKENHI-PROJECT-17025025
[Journal Article] Another way to die : autophagic programmed cell death.2005
- Author(s)
  Tsujimoto Y, Shimizu S.
- Journal Title
  
  Cell Death Differ 12
  
  Pages: 1528-1534
- Data Source
  KAKENHI-PROJECT-17591331
[Journal Article] Two distinct Fas-activated signaling pathways revealed by an anti-tumor drug D6092005
- Author(s)
  L.Zhang, S.Shimizu, Y.Tsujimoto
- Journal Title
  
  Oncogene 24
  
  Pages: 2954-2962
- Data Source
  KAKENHI-PROJECT-17025025
[Journal Article] Two distinct Fas-activated signaling pathways revealed by an anti-tumor drug D6092005
- Author(s)
  L.Zhang, S.Shimizu.Y.Tsujimoto
- Journal Title
  
  Oncogene 24
  
  Pages: 2954-2962
- Data Source
  KAKENHI-PROJECT-17390094
[Journal Article] A role of Bcl-2 family of proteins in non-apoptotic programmed cell death dependent on autophagy genes.2004
- Author(s)
  Shimizu, S., et al.
- Journal Title
  
  Nature Cell Biol. 6
  
  Pages: 1221-1228
- Data Source
  KAKENHI-PROJECT-16023240
[Journal Article] Role of the mitochondrial membrane permeability transition in cell death.
- Author(s)
  Tsujimoto, Y., Shimizu, S.
- Journal Title
  
  Apoptosis (印刷中)
- Data Source
  KAKENHI-PROJECT-18023024
[Journal Article] オートファジーの新たな展開とそれによる炎症制御
- Author(s)
  清水重臣
- Journal Title
  
  細胞工学
  
  Volume: (印刷中)
- Data Source
  KAKENHI-PROJECT-22247016
[Journal Article] 神経変性疾患とミトコンドリア傷害
- Author(s)
  清水重臣
- Journal Title
  
  神経変性疾患のサイエンス (印刷中)
- Data Source
  KAKENHI-PROJECT-17390094
[Journal Article] 神経変性疾患とミトコンドリア傷害
- Author(s)
  清水重臣
- Journal Title
  
  神経変性疾患のサイエンス (印刷中)
- Data Source
  KAKENHI-PROJECT-18023024
[Journal Article] Role of the mitochondrial membrane permeability transition in cell death.
- Author(s)
  Tsujimoto, Y., Shimizu, S.
- Journal Title
  
  Apoptosis (印刷中)
- Data Source
  KAKENHI-PROJECT-17390094
[Journal Article] Atg5非依存性オートファジーの形態学と分子生物学
- Author(s)
  清水重臣、荒川聡子、西田友哉
- Journal Title
  
  顕微鏡
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22247016
[Presentation] オートファジーと疾患2018
- Author(s)
  清水重臣
- Organizer
  第6回AAA会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06414
[Presentation] オートファジーと疾患2018
- Author(s)
  清水重臣
- Organizer
  第6回AAA会
- Invited
- Data Source
  KAKENHI-ORGANIZER-17H06413
[Presentation] 新規オートファジーの分子機構とその破綻による疾患2017
- Author(s)
  清水重臣
- Organizer
  第22回日本病態プロテアーゼ学会
- Invited
- Data Source
  KAKENHI-PROJECT-16K15230
[Presentation] Development of molecularly targeted anticancer agents based on the regulation of autophagic cell death2017
- Author(s)
  清水重臣
- Organizer
  第76回日本癌学会
- Invited
- Data Source
  KAKENHI-ORGANIZER-17H06413
[Presentation] 新規オートファジーの分子機構とその破綻による疾患2017
- Author(s)
  清水重臣
- Organizer
  第22回日本病態プロテアーゼ学会
- Invited
- Data Source
  KAKENHI-ORGANIZER-17H06413
[Presentation] 新規オートファジーの分子機構とその破綻による疾患2017
- Author(s)
  清水重臣
- Organizer
  第22回日本病態プロテアーゼ学会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06414
[Presentation] オートファジーが関わる細胞死2017
- Author(s)
  清水重臣
- Organizer
  日本Cell Death学会
- Data Source
  KAKENHI-PROJECT-16K15230
[Presentation] Development of molecularly targeted anticancer agents based on the regulation of autophagic cell death2017
- Author(s)
  清水重臣
- Organizer
  第76回日本癌学会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06414
[Presentation] オートファジーが関わる細胞死2017
- Author(s)
  清水重臣
- Organizer
  日本Cell Death学会
- Invited
- Data Source
  KAKENHI-ORGANIZER-17H06413
[Presentation] オートファジーが関わる細胞死2017
- Author(s)
  清水重臣
- Organizer
  日本Cell Death学会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06414
[Presentation] Development of molecularly targeted anticancer agents based on the regulation of autophagic cell death2017
- Author(s)
  清水重臣
- Organizer
  第76回日本癌学会
- Data Source
  KAKENHI-PROJECT-16K15230
[Presentation] Mitophagy and alternative autophagy2016
- Author(s)
  Shimizu S
- Organizer
  The 13th Conference of Asian Society for Mitochondrial Research and Medicine
- Place of Presentation
  TKP Garden City Shinagawa, Shinagawa
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01554
[Presentation] Mitophagy and alternative autophagy2016
- Author(s)
  Shimizu S
- Organizer
  The 13th Conference of Asian Society for Mitochondrial Research and Medicine
- Place of Presentation
  TKP Garden City Shinagawa, Shinagawa
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15230
[Presentation] Identification of natural product against fatty liver disease based on the induction of alternative autophagy2016
- Author(s)
  Shimizu S
- Organizer
  ICNIM2016
- Place of Presentation
  Hotel Royton, Sapporo
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15230
[Presentation] Macroautophagy mediates elimination of mitochondria from embryonic reticulocytes2016
- Author(s)
  清水重臣
- Organizer
  第78回日本血液学会
- Place of Presentation
  パシフィコ横浜, 横浜
- Invited
- Data Source
  KAKENHI-PROJECT-16K15230
[Presentation] Alternative Autophagy is Essential for Neuronal Cell Maintenance2016
- Author(s)
  Shimizu S
- Organizer
  Brain Protein Aging and Dementia Control International Workshop
- Place of Presentation
  Kakuyu Kaikan in Nagoya University, Nagoya
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15230
[Presentation] Molecular mechanisms of Atg5-independent alternative autophagy2016
- Author(s)
  Shimizu S
- Organizer
  Gordon Research Conference.
- Place of Presentation
  ロスアンジェルス（米国）
- Year and Date
  2016-03-20
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01554
[Presentation] Alternative Autophagy is Essential for Neuronal Cell Maintenance2016
- Author(s)
  Shimizu S
- Organizer
  Brain Protein Aging and Dementia Control International Workshop
- Place of Presentation
  Kakuyu Kaikan in Nagoya University, Nagoya
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01554
[Presentation] Identification of natural product against fatty liver disease based on the induction of alternative autophagy2016
- Author(s)
  Shimizu S
- Organizer
  ICNIM2016
- Place of Presentation
  Hotel Royton, Sapporo
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01554
[Presentation] Macroautophagy mediates elimination of mitochondria from embryonic reticulocytes2016
- Author(s)
  清水重臣
- Organizer
  第78回日本血液学会
- Place of Presentation
  パシフィコ横浜、横浜
- Invited
- Data Source
  KAKENHI-PUBLICLY-15H01554
[Presentation] Development of Small Compound against Polyglutamine Diseases based on the Regulation of Alternative Autophagy2015
- Author(s)
  Shimizu S
- Organizer
  Brain Protein Aging and Dementia Control　1st InternationalSymposium
- Place of Presentation
  野依記念学術交流館（愛知県・名古屋市）
- Year and Date
  2015-10-09
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01554
[Presentation] Biological Roles of Autophagic Cell Death2015
- Author(s)
  Shimizu S
- Organizer
  Japan Australia Meeting on Cell Death
- Place of Presentation
  メルボルン（オーストラリア）
- Year and Date
  2015-10-21
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01554
[Presentation] 新しく発見したオートファジー機構とオルガネラ分解2014
- Author(s)
  清水重臣
- Organizer
  第５７回日本神経化学会大会
- Place of Presentation
  奈良市
- Year and Date
  2014-09-29
- Invited
- Data Source
  KAKENHI-PROJECT-22229002
[Presentation] 新しく発見したオートファジーと肝疾患2014
- Author(s)
  清水重臣
- Organizer
  第21回　肝細胞研究会
- Place of Presentation
  文京区
- Year and Date
  2014-06-28
- Invited
- Data Source
  KAKENHI-PROJECT-25670139
[Presentation] 新しく発見したオートファジー機構とオルガネラ分解2014
- Author(s)
  清水重臣
- Organizer
  第５７回日本神経化学会大会
- Place of Presentation
  奈良市
- Year and Date
  2014-09-29
- Invited
- Data Source
  KAKENHI-PROJECT-25670139
[Presentation] オートファジー破綻に起因する発癌機構の解明とその抗癌剤開発への応用2014
- Author(s)
  清水重臣
- Organizer
  第13回南大阪癌フォーラム
- Place of Presentation
  堺市
- Year and Date
  2014-04-19
- Invited
- Data Source
  KAKENHI-PROJECT-22229002
[Presentation] オートファジー破綻に起因する発癌機構の解明とその抗癌剤開発への応用2014
- Author(s)
  清水重臣
- Organizer
  第13回南大阪癌フォーラム
- Place of Presentation
  堺市
- Year and Date
  2014-04-19
- Invited
- Data Source
  KAKENHI-PROJECT-25670139
[Presentation] 新しく発見したオートファジーと肝疾患2014
- Author(s)
  清水重臣
- Organizer
  第21回　肝細胞研究会
- Place of Presentation
  文京区
- Year and Date
  2014-06-28
- Invited
- Data Source
  KAKENHI-PROJECT-22229002
[Presentation] Mitophagy is regulated by Ulk1-dependent alternative macroautophagy during erythrocyte maturation2013
- Author(s)
  Shimizu S
- Organizer
  International Symposium on Mitochondria
- Place of Presentation
  Tokyo, Japan
- Invited
- Data Source
  KAKENHI-PROJECT-25670139
[Presentation] Mitophagy is regulated by Ulk1-dependent alternative macroautophagy during erythrocyte maturation2013
- Author(s)
  Shimizu S
- Organizer
  International Symposium on Mitochondria
- Place of Presentation
  Tokyo, Japan
- Invited
- Data Source
  KAKENHI-PUBLICLY-24121708
[Presentation] オートファジーと細胞死のクロストーク2013
- Author(s)
  清水重臣
- Organizer
  第22回日本Cell Death学会
- Place of Presentation
  京都
- Invited
- Data Source
  KAKENHI-PROJECT-25670139
[Presentation] Biological Roles of Autophagic Cell Death” CSH Asia conference on Mechanisms and Functions of Non-apoptotic Cell Death2013
- Author(s)
  Shimizu S
- Organizer
  CSH Asia conference on Mechanisms and Functions of Non-apoptotic Cell Death
- Place of Presentation
  Suzhou, China
- Invited
- Data Source
  KAKENHI-PROJECT-25670139
[Presentation] Biological roles of Autophagic cell death2013
- Author(s)
  Shimizu S
- Organizer
  第86回日本生化学会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PROJECT-22229002
[Presentation] オートファジーと細胞死のクロストーク2013
- Author(s)
  清水重臣
- Organizer
  第22回日本Cell Death学会
- Place of Presentation
  京都
- Invited
- Data Source
  KAKENHI-PROJECT-22229002
[Presentation] Mitophagy is regulated by Ulk1-dependent alternative macroautophagy during erythrocyte maturation2013
- Author(s)
  Shimizu S
- Organizer
  International Symposium on Mitochondria
- Place of Presentation
  Tokyo, Japan
- Invited
- Data Source
  KAKENHI-PROJECT-22229002
[Presentation] Biological Roles of Autophagic Cell Death2013
- Author(s)
  Shimizu S
- Organizer
  CSH Asia conference on Mechanisms and Functions of Non-apoptotic Cell Death
- Place of Presentation
  Suzhou, China
- Invited
- Data Source
  KAKENHI-PUBLICLY-24121708
[Presentation] オートファジーと細胞死のクロストーク2013
- Author(s)
  清水重臣
- Organizer
  第22回日本Cell Death学会
- Place of Presentation
  京都
- Invited
- Data Source
  KAKENHI-PUBLICLY-24121708
[Presentation] Biological Roles of Autophagic Cell Death2013
- Author(s)
  Shimizu S
- Organizer
  CSH Asia conference on Mechanisms and Functions of Non-apoptotic Cell Death
- Place of Presentation
  Suzhou, China
- Invited
- Data Source
  KAKENHI-PROJECT-22229002
[Presentation] Biological Roles of Autophagic Cell Death2013
- Author(s)
  Shimizu S
- Organizer
  第86回日本生化学会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PROJECT-25670139
[Presentation] Molecular Mechanisms and Physiological Roles of Atg5/Atg7-independent Macroautophagy2012
- Author(s)
  Shigeomi Shimizu
- Organizer
  The 6th Symposium on Autophagy
- Place of Presentation
  名護市
- Data Source
  KAKENHI-PROJECT-23657084
[Presentation] 様々なストレスに対応する為に機能するオートファジー2012
- Author(s)
  清水重臣
- Organizer
  第16回日本統合医療学会
- Place of Presentation
  豊中市
- Invited
- Data Source
  KAKENHI-PROJECT-22229002
[Presentation] Alternative Macroautophagy and Cancer2012
- Author(s)
  Shigeomi Shimizu
- Organizer
  第71回日本癌学会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-23657084
[Presentation] Maintenance of tissue homeostasis by dying cells and autophagy2012
- Author(s)
  清水重臣
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡市
- Data Source
  KAKENHI-PROJECT-22229002
[Presentation] なぜ赤血球にはミトコンドリアがないのか?～オートファジーの働き2012
- Author(s)
  清水重臣
- Organizer
  第3回ミトコンドリアとDDS
- Year and Date
  2012-07-07
- Data Source
  KAKENHI-PROJECT-23657084
[Presentation] Alternative Macroautophagy and Cancer2012
- Author(s)
  清水重臣
- Organizer
  第71回日本癌学会
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PROJECT-23657084
[Presentation] Molecular Mechanisms andPhysiological Roles of Atg5/Atg7- independent Macroautophagy2012
- Author(s)
  Shimizu S
- Organizer
  The 6th Symposium on Autophagy
- Year and Date
  2012-10-30
- Data Source
  KAKENHI-PROJECT-23657084
[Presentation] 放射線によって誘導される様々な細胞死とオートファジー2012
- Author(s)
  清水重臣
- Organizer
  第2回分子状水素医学シンポジウム
- Year and Date
  2012-02-11
- Data Source
  KAKENHI-PROJECT-23657084
[Presentation] Maintenance of tissue homeostasis by dying cells and autophagy2012
- Author(s)
  清水重臣
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡市
- Year and Date
  2012-12-11
- Data Source
  KAKENHI-PUBLICLY-24121708
[Presentation] Molecular Mechanisms and Physiological Roles of Atg5/Atg7-independent Macroautophagy2012
- Author(s)
  Shigeomi Shimizu
- Organizer
  The 6th Symposium on Autophagy
- Place of Presentation
  名護市
- Data Source
  KAKENHI-PROJECT-22229002
[Presentation] Alternative Macroautophagy and Cancer2012
- Author(s)
  Shigeomi Shimizu
- Organizer
  第71回日本癌学会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-22229002
[Presentation] Molecular Mechanisms and Physiological Roles of Atg5/Atg7-independent Macroautophagy2012
- Author(s)
  Shigeomi Shimizu
- Organizer
  The 6th Symposium on Autophagy
- Place of Presentation
  名護市
- Year and Date
  2012-10-28
- Data Source
  KAKENHI-PUBLICLY-24121708
[Presentation] 様々なストレスに対応する為に機能するオートファジー2012
- Author(s)
  清水重臣
- Organizer
  第16回日本統合医療学
- Place of Presentation
  豊中市
- Year and Date
  2012-12-08
- Invited
- Data Source
  KAKENHI-PUBLICLY-24121708
[Presentation] Maintenance of tissue homeostasis by dying cells and autophagy2012
- Author(s)
  清水重臣
- Organizer
  第35回日本分子生物学会
- Year and Date
  2012-12-13
- Data Source
  KAKENHI-PROJECT-23657084
[Presentation] Alternative Macroautophagy and Cancer2012
- Author(s)
  Shigeomi Shimizu
- Organizer
  第71回日本癌学会
- Place of Presentation
  札幌市
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PUBLICLY-24121708
[Presentation] 様々なストレスに対応する為に機能するオートファジー2012
- Author(s)
  清水重臣
- Organizer
  第16回日本統合医療学会
- Year and Date
  2012-12-09
- Data Source
  KAKENHI-PROJECT-23657084
[Presentation] アポトーシスと非アポトーシス細胞死2011
- Author(s)
  清水重臣
- Organizer
  第73回日本血液学会
- Place of Presentation
  名古屋市(招待講演)
- Year and Date
  2011-10-14
- Data Source
  KAKENHI-PUBLICLY-22020009
[Presentation] アポトーシスと非アポトーシス細胞死2011
- Author(s)
  清水重臣
- Organizer
  第73回日本血液学会
- Data Source
  KAKENHI-PROJECT-23657084
[Presentation] 様々な疾患を惹起するミトコンドリア細胞死孔の解析2011
- Author(s)
  清水重臣
- Organizer
  第84回日本生化学会
- Place of Presentation
  京都市
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PUBLICLY-22020009
[Presentation] 細胞死とオートファジーのクロストーク2011
- Author(s)
  清水重臣
- Organizer
  日本Cell Death学会
- Place of Presentation
  文京区
- Year and Date
  2011-07-29
- Data Source
  KAKENHI-PUBLICLY-22121505
[Presentation] 細胞死とオートファジーのクロストーク2011
- Author(s)
  清水重臣
- Organizer
  日本Cell Death学会
- Place of Presentation
  文京区
- Year and Date
  2011-07-29
- Data Source
  KAKENHI-PUBLICLY-22020009
[Presentation] オートファジーと神経変性疾患2011
- Author(s)
  清水重臣
- Organizer
  「病態に根ざしたALSの新規治療法開発班」平成23年度ワークショップ
- Place of Presentation
  千代田区(招待講演)
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PUBLICLY-22020009
[Presentation] オートファジーを標的とした難治疾患克服への戦略2011
- Author(s)
  清水重臣
- Organizer
  新適塾「難病への挑戦」(招待講演)
- Place of Presentation
  豊中市
- Data Source
  KAKENHI-PROJECT-23657084
[Presentation] 生体で見られる様々な細胞死とオートファジー2011
- Author(s)
  清水重臣
- Organizer
  第1回横断的腫瘍フォーラム
- Place of Presentation
  吹田市(招待講演)
- Year and Date
  2011-12-07
- Data Source
  KAKENHI-PUBLICLY-22121505
[Presentation] Alternative macroautophagy2011
- Author(s)
  Shigeomi Shimizu
- Organizer
  Parkinson Disease and Mitophagy
- Place of Presentation
  文京区
- Year and Date
  2011-06-11
- Data Source
  KAKENHI-PUBLICLY-22020009
[Presentation] Alternativemacroautophagy International Symposium2011
- Author(s)
  Shimizu S.
- Organizer
  Parkinson Disease and Mitophagy
- Year and Date
  2011-06-11
- Data Source
  KAKENHI-PROJECT-23657084
[Presentation] オートファジーと神経変性疾患2011
- Author(s)
  清水重臣
- Organizer
  「病態に根ざしたALSの新規治療法開発班」平成23年度ワークショップ(招待講演)
- Place of Presentation
  千代田区
- Data Source
  KAKENHI-PROJECT-23657084
[Presentation] 生体で見られる様々な細胞死とオートファジー2011
- Author(s)
  清水重臣
- Organizer
  第1回横断的腫瘍フォーラム
- Place of Presentation
  吹田市(招待講演)
- Year and Date
  2011-12-07
- Data Source
  KAKENHI-PUBLICLY-22020009
[Presentation] アポトーシスと非アポトーシス細胞死2011
- Author(s)
  清水重臣
- Organizer
  第73回日本血液学会
- Place of Presentation
  名古屋市(招待講演)
- Year and Date
  2011-10-14
- Data Source
  KAKENHI-PUBLICLY-22121505
[Presentation] 様々な疾患を惹起するミトコンドリア細胞死孔の解析2011
- Author(s)
  清水重臣
- Organizer
  第84回日本生化学会
- Place of Presentation
  京都市
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PUBLICLY-22121505
[Presentation] オートファジーと神経変性疾患2011
- Author(s)
  清水重臣
- Organizer
  「病態に根ざしたALSの新規治療法開発班」平成23年度ワークショップ
- Place of Presentation
  千代田区(招待講演)
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PUBLICLY-22121505
[Presentation] アポトーシスと非アポトーシス細胞死2011
- Author(s)
  清水重臣
- Organizer
  第73回日本血液学会
- Place of Presentation
  名古屋市(招待講演)
- Year and Date
  2011-10-14
- Data Source
  KAKENHI-PROJECT-22229002
[Presentation] Various Types of Cell Death and Autophagy2011
- Author(s)
  Shigeomi Shimizu
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜市
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PUBLICLY-22121505
[Presentation] 細胞死を司るミトコンドリア孔の解析2011
- Author(s)
  清水重臣
- Organizer
  過渡的複合体シンポジウム
- Year and Date
  2011-07-21
- Data Source
  KAKENHI-PROJECT-23657084
[Presentation] Alternative macroautophagy2011
- Author(s)
  Shigeomi Shimizu
- Organizer
  Parkinson Disease and Mitophagy
- Place of Presentation
  文京区
- Data Source
  KAKENHI-PROJECT-23657084
[Presentation] オートファジーと神経変性疾患病態に根ざしたALSの新規治療法開発班2011
- Author(s)
  清水重臣
- Organizer
  平成23年度ワークショップ
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-23657084
[Presentation] オートファジーを標的とした難治疾患克服への戦略2011
- Author(s)
  清水重臣
- Organizer
  新適塾「難病への挑戦」第7回
- Year and Date
  2011-09-02
- Data Source
  KAKENHI-PROJECT-23657084
[Presentation] Alternative macroautophagy2011
- Author(s)
  Shigeomi Shimizu
- Organizer
  Parkinson Disease and Mitophagy
- Place of Presentation
  文京区
- Year and Date
  2011-06-11
- Data Source
  KAKENHI-PUBLICLY-22121505
[Presentation] オートファジーを標的とした難治疾患克服への戦略2011
- Author(s)
  清水重臣
- Organizer
  新適塾「難病への挑戦」
- Place of Presentation
  豊中市(招待講演)
- Year and Date
  2011-09-02
- Data Source
  KAKENHI-PUBLICLY-22121505
[Presentation] 細胞死とオートファジーのクロストーク2011
- Author(s)
  清水重臣
- Organizer
  日本Cell Death学会
- Year and Date
  2011-07-29
- Data Source
  KAKENHI-PROJECT-23657084
[Presentation] オートファジーを標的とした難治疾患克服への戦略2011
- Author(s)
  清水重臣
- Organizer
  新適塾「難病への挑戦」
- Place of Presentation
  豊中市(招待講演)
- Year and Date
  2011-09-02
- Data Source
  KAKENHI-PROJECT-22229002
[Presentation] 細胞死とオートファジーのクロストーク2011
- Author(s)
  清水重臣
- Organizer
  日本Cell Death学会
- Place of Presentation
  文京区
- Year and Date
  2011-07-29
- Data Source
  KAKENHI-PROJECT-22229002
[Presentation] 様々な疾患を惹起するミトコンドリア細胞死孔の解析2011
- Author(s)
  清水重臣
- Organizer
  第84回日本生化学会
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-23657084
[Presentation] オートファジーと神経変性疾患2011
- Author(s)
  清水重臣
- Organizer
  「病態に根ざしたALSの新規治療法開発班」平成23年度ワークショップ
- Place of Presentation
  千代田区(招待講演)
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-22229002
[Presentation] 生体で見られる様々な細胞死とオートファジー2011
- Author(s)
  清水重臣
- Organizer
  第1回横断的腫瘍フォーラム
- Place of Presentation
  吹田市(招待講演)
- Year and Date
  2011-12-07
- Data Source
  KAKENHI-PROJECT-22229002
[Presentation] オートファジーを標的とした難治疾患克服への戦略2011
- Author(s)
  清水重臣
- Organizer
  新適塾「難病への挑戦」
- Place of Presentation
  豊中市(招待講演)
- Year and Date
  2011-09-02
- Data Source
  KAKENHI-PUBLICLY-22020009
[Presentation] 様々な疾患を惹起するミトコンドリア細胞死孔の解析2011
- Author(s)
  清水重臣
- Organizer
  第84回日本生化学会
- Place of Presentation
  京都市
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-22229002
[Presentation] Various Types of Cell Death and Autophagy2011
- Author(s)
  Shigeomi Shimizu
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜市
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-22229002
[Presentation] Alternative macroautophagy2011
- Author(s)
  Shigeomi Shimizu
- Organizer
  Parkinson Disease and Mitophagy
- Place of Presentation
  文京区
- Year and Date
  2011-06-11
- Data Source
  KAKENHI-PROJECT-22229002
[Presentation] Various Types of Cell Death and Autophagy2011
- Author(s)
  Shigeomi Shimizu
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-23657084
[Presentation] オートファジーを標的とした難治疾患克服への戦略2011
- Author(s)
  清水重臣
- Organizer
  金沢大学がん進展制御研究所セミナー
- Year and Date
  2011-09-27
- Data Source
  KAKENHI-PROJECT-23657084
[Presentation] Various Types of Cell Death and Autophagy2011
- Author(s)
  Shigeomi Shimizu
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜市
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PUBLICLY-22020009
[Presentation] アポトーシスと非アポトーシス細胞死2011
- Author(s)
  清水重臣
- Organizer
  第73回日本血液学会(招待講演)
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-23657084
[Presentation] 生体で見られる様々な細胞死とオートファジー2011
- Author(s)
  清水重臣
- Organizer
  第1回横断的腫瘍フォーラム
- Year and Date
  2011-12-07
- Data Source
  KAKENHI-PROJECT-23657084
[Presentation] A critical role for the autophagy gene Ulkl in Atg5- independent alternative macroautophagy2010
- Author(s)
  S.Shimizu
- Organizer
  Gordon Conference
- Place of Presentation
  Italy
- Year and Date
  2010-04-25
- Data Source
  KAKENHI-PROJECT-22229002
[Presentation] A critical role for the autophagy gene Ulk1 in Atg5-independent alternative macroautophagy2010
- Author(s)
  Shimizu S.
- Organizer
  Gordon Conference
- Place of Presentation
  イタリア
- Year and Date
  2010-04-29
- Data Source
  KAKENHI-PROJECT-22247016
[Presentation] Discovery of AtgS/Atg7-independent alternative macroautophagy2010
- Author(s)
  S.Shimizu
- Organizer
  6^<th> Institute network symposium
- Place of Presentation
  Kanazawa
- Year and Date
  2010-06-25
- Data Source
  KAKENHI-PROJECT-21659076
[Presentation] Discovery of Atg5/Atg7-independent alternative macroautophagy2010
- Author(s)
  S.Shimizu
- Organizer
  6^<th> Institute network symposium
- Place of Presentation
  Kanazawa
- Year and Date
  2010-06-25
- Data Source
  KAKENHI-PUBLICLY-22020009
[Presentation] Multiple mechanisms of cell death and their regulation by mitochondria2010
- Author(s)
  S.Shimizu
- Organizer
  第74回日本循環器学会
- Place of Presentation
  京都
- Year and Date
  2010-03-05
- Data Source
  KAKENHI-PROJECT-21659076
[Presentation] Various Types of CellDeath and Autophagy2010
- Author(s)
  Shimizu S
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23657084
[Presentation] A critical role for the autophagy gene Ulk1 in Atg5- independent alternative macroautophagy2010
- Author(s)
  S.Shimizu
- Organizer
  Gordon Conference
- Place of Presentation
  Lucca, Italy
- Year and Date
  2010-04-25
- Data Source
  KAKENHI-PUBLICLY-22121505
[Presentation] A critical role for the autophagy gene U1k1 in Atg5- independent alternative macroautophagy2010
- Author(s)
  S.Shimizu
- Organizer
  Gordon Conference
- Place of Presentation
  Italy
- Year and Date
  2010-04-25
- Data Source
  KAKENHI-PROJECT-21659076
[Presentation] Discovery of Atg5/Atg7-independent alternative macroautophagy2010
- Author(s)
  S.Shimizu
- Organizer
  6^<th> Institute network symposium
- Place of Presentation
  Kanazawa
- Year and Date
  2010-06-25
- Data Source
  KAKENHI-PUBLICLY-22121505
[Presentation] Discovery of AtgS/Atg7-independent alternative macroautophagy2010
- Author(s)
  S.Shimizu
- Organizer
  6^<th> Institute network symposium
- Place of Presentation
  Kanazawa
- Year and Date
  2010-06-25
- Data Source
  KAKENHI-PROJECT-22229002
[Presentation] A critical role for the autophagy gene Ulkl in Atg5- independent alternative macroautophagy2010
- Author(s)
  S.Shimizu
- Organizer
  Gordon Conference
- Place of Presentation
  Lucca, Italy
- Year and Date
  2010-04-25
- Data Source
  KAKENHI-PUBLICLY-22020009
[Presentation] 1. Multiple mechanisms of cell death and their regulationby Bcl-22008
- Author(s)
  Shigeomi Shimizu
- Organizer
  JAACT2008
- Place of Presentation
  Fukuoka
- Year and Date
  2008-11-25
- Data Source
  KAKENHI-PROJECT-19659349
[Presentation] MITOCHONDRIA and NON-APOPTOTIC CELL DEATH.2007
- Author(s)
  Shimizu S
- Organizer
  4th Annual Meeting of Asian Society for Mitochondrial Research and Medicine,
- Place of Presentation
  Seoul
- Data Source
  KAKENHI-PROJECT-18023024
[Presentation] Physiological Role of Atg5-independent macroautophagy
- Author(s)
  Shimizu S
- Organizer
  The 16th Northeastern Asian Symposium
- Place of Presentation
  Busan, Korea
- Year and Date
  2014-12-19 – 2014-12-20
- Invited
- Data Source
  KAKENHI-PROJECT-25670139
[Presentation] Physiological Role of Atg5-independent macroautophagy
- Author(s)
  Shimizu S
- Organizer
  The 16th Northeastern Asian Symposium
- Place of Presentation
  Busan, Korea
- Year and Date
  2014-12-19 – 2014-12-20
- Invited
- Data Source
  KAKENHI-PROJECT-22229002
[Presentation] Development of Molecularly Targeted Anticancer Agents Based on the Regulation of Autophagic Cell Death
- Author(s)
  Shimizu S
- Organizer
  The Uehara Memorial Foundation Symposium 2014
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2014-06-15 – 2014-06-17
- Invited
- Data Source
  KAKENHI-PROJECT-25670139
[Presentation] Development of Molecularly Targeted Anticancer Agents Based on the Regulation of Autophagic Cell Death
- Author(s)
  Shimizu S
- Organizer
  The Uehara Memorial Foundation Symposium 2014
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2014-06-15 – 2014-06-17
- Invited
- Data Source
  KAKENHI-PROJECT-22229002

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SHIMIZU Shigeomi 清水 重臣

Research Projects

Research Products

Co-Researchers

Atg5非依存的オートファジー誘導活性化合物のマウス腸炎モデルに対する効果の検討Ongoing

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

Regulation of brain aging by alternative autophagyPrincipal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Analysis of "Response zone" and " Communication zone" in mitochondria and Golgi apparatusPrincipal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Toward an integrative understanding of functional zones in organellesArea Organizer

Area Organizer

Project Period (FY)

Research Category

Toward an integrative understanding of functional zones in organellesPrincipal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Biological roles of novel proteolytic mechanism GOMEDPrincipal InvestigatorOngoing

Principal Investigator

Project Period (FY)

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Research Institution

Development of small compounds that induce alternative autophagyPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

新規オートファジーによる脳老化タンパク質調節機構の解析と創薬開発研究Principal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Development of autophagy visualization tools and analyses of physiological roles of autophagyPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

ミトコンドリア膜上に一過性に形成される過渡的細胞死孔の捕捉Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Structural analysis of mitochondrial apoptotic porePrincipal Investigator

Principal Investigator

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Research Institution

新しく発見したオートファジー機構を介した蛋白質品質管理システムの解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ミトコンドリア膜上に一過性に形成される過渡期細胞死孔の捕捉Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

SHIMIZU Shigeomi 清水重臣