Tahara Hideaki 田原秀晃

… Alternative Names

TAHARA HIDEAKI 田原秀晃

TAHARA Hideaki 田原秀晃

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Researcher Number	70322071
External Links
Affiliation (Current)	2023: 地方独立行政法人大阪府立病院機構大阪国際がんセンター(研究所), その他部局等, 研究所部長
Affiliation (based on the past Project Information) *help	2018 – 2022: 東京大学, 医科学研究所, 特任教授 2017: 東京大学, 医科学研究所, 教授 2000 – 2015: 東京大学, 医科学研究所, 教授 2007: 東京大学, 癌研究所・医科学研究所, 教授
Review Section/Research Field	Principal Investigator Biological Sciences / General surgery / General surgery Except Principal Investigator General surgery / General surgery / Basic Section 50020:Tumor diagnostics and therapeutics-related / Digestive surgery / Biological Sciences / Digestive surgery / Ophthalmology … More / 医療における生命倫理 / Virology / Tumor therapeutics / Medium-sized Section 50:Oncology and related fields Less
Keywords	Principal Investigator 遺伝子治療 / 樹状細胞 / 腫瘍免疫 / サイトカイン / 免疫学 / GMP / がん治療 / tumor immunology / dendritic cells / adenoviral vector … More / 癌 / 生体機能利用 / 遺伝子 / NK細胞 / 実験外科学 / 臨床研究 / ウイルスベクター / IL-18 / Interleukin-12 / gene Therapy / Inteleukin-12 / translational research / バイオテクノロジー / 癌免疫療法 / 非特異的免疫 / 特異的免疫 / 細胞性免疫 / 自然免疫 / 獲得免疫 / 遺伝子導入 / NK-T細胞 / 細胞傷害性T細胞 / 細胞障害性T細胞 / 細胞療法 / ウィルスベクター / アデノウィルス・ベクター / レトロウィルス・ベクター / インターロイキン / in vivo electroporation / アデノウイル・スベクター / レトロウイルス・ベクター / gene therapy / cytokine / NK cells / retroviral vector / アデノウイルスベクター / 探索的医療 / IL-12 / 樹上細胞 / アデノウィルスベクター / RCA / がん免疫療法 / 腫瘍溶解性ウイルス療法 / 免疫 / トランスレーショナルリサーチ … More Except Principal Investigator 遺伝子治療 / 樹状細胞 / Flt3L / HLA / dendritic cell / ウイルスベクター / SLC / がん / トランスレーショナル・リサーチ / in vivo electroporation / CTL / IL-18 / トランスレーショナルリサーチ / 免疫学 / ペプチド / マウス / 免疫寛容 / chemokine / peptide / regulatory T cell / CD4+CD25+ / thymus / 腫瘍溶解性ウイルス療法 / ヘルペスウイルス / 抗体 / GM-CSF / 細胞療法 / ウイルス / 遺伝子 / 高分子ミセル / 抗腫瘍効果 / DC / 移植 / トランスジェニックマウス / OK-432 / electroporation / RNA / 癌 / 免疫療法 / cancer / immunotherapy / エピトープペプチド / HER2 / neu / p53 / がんワクチン / がんワクチン療法 / Epitope peptide / Cancer vaccine / VEGFR2 / PKR / ras / VAI / CCL21 / がん免疫療法 / 免疫チェックポイント / MFG-E8 / 免疫遺伝子治療 / SEREX法 / cDNA発現ファージライブラリー / コモンマーモセット / 急性リンパ性白血病 / 成人T細胞性白血病 / LAM-PCR法 / SEREX / 腎癌腫瘍抗原 / SEREX抗原 / フィラデルフィア染色体陽性急性リンパ性白血病 / マキシザイム / VSV-Gシュードタイプレンチウイルスベクター / CD19リポソーム / bcr / abl遺伝子 / SAGE法 / 顆粒球マクロファージコロニー刺激因子遺伝子 / 抗コモンマーモセットCD34単クローン抗体 / BAI-1遺伝子 / p51遺伝子 / Tob遺伝子 / IL-18遺伝子 / アデノウイルスベクター / レトロウイルスベクター / 抗腫瘍免疫誘導 / 細胞傷害性T細胞 / 非ウイルスベクター / 癌抑制遺伝子 / カチオニックリポソーム / Qplex / C型肝炎ウイルス細胞障害領域 / LPD / Fusogenic peptide / カチオニックリボソーム / cGMP / 品質管理 / マネジメント・システム / TNF一α / YB-1 / CD40L / miRNA / TNF-α / TNF-α遺伝子 / ROS / Rac-1 / 再生医療 / 細胞医療 / 科学教育 / interleukin-23 / CTLA-4 / PD-1 / TIM-3 / IL-23 / 免疫監視機構 / 遺伝子導入 / 免疫制御 / 異所性心移植モデル / HLAクラスI抗原 / Peptide / Genetic modification / Dendritic Cell / Mouse / Transplantation / Tolerance / FasL(CD95L)導入癌細胞 / 癌遺伝子療法 / アポトーシス / 好中球浸潤 / MH134肝癌 / 抗Fas抗体 / 耐性腫瘍 / Fasリガンド発現腫瘍 / 抗腫瘍作用 / 肝癌MH134 / FasL発現腫瘍 / MH134 / FasL(CD95L)-transfected tumor cell / Cancer gene therapy / Apoptosis / Anti-tumor effect / Neutrophil infiltration / MH134 hepatoma / Anti-Fas antibody / Resistant tumor / インターロイキン 12 / インターロイキン12 / gene therapy / viral vector / interleukin-12 / ケモカイン / CCR7 / 腫瘍免疫 / 臓器移植 / 骨髄移植 / ビタミンD / tolerance / 骨髄非破壊的幹細胞移植 / dendritic cells / genetherapy / in vitro electroporation / denderitic cell / 組織適合性抗原 / 調節性T細胞 / CD4陽性CD25陽性 / 胸腺 / CD4+CD25+T細胞 / 心移植 / 移植免疫 / CD4CD25 / 制御性T cell / FoxP3 / transgenic mouse / 腫瘍の多様性 / HLA欠損 / 細胞障害性T細胞 / Tumor heterogenicity / HLA Loss / immunology / gene / translational research / virus / 加齢黄斑変性 / 光線力学療法 / 脈絡膜新生血管 / 特異的免疫賦活化療法 / サルゲノムマイクロアレイ / ナノバイオ / 移植・再生医療 / マイクロアレイ / age-related macular degeneration / photodynamic therapy / polyion complex micelle / choroidal neovascularization / genome microarray chips / アデノウイルス / ベクター / 膵がん / インターフェロン / IFN / Adenovirus / Vector / Gene Therapy / Pancreatic Cancer / Interferon / FIt3L / 利益相反 / 探索型医療 / インフォームド・コンセント / Conflict of Interest / Translational Research / Informed Consent / 腫瘍溶解ウイルス療法 / 造血器腫瘍 / PD-L1 / PD-L2 / 抗がん剤 / 化学免疫併用療法 / マクロファージ Less

膜融合能増強型標的化ヘルペスウイルスのさらなる改変による抗腫瘍免疫誘導能の増強
- Principal Investigator
  
  内田宏昭
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  The University of Tokyo
化学療法により誘導される免疫認識シグナル規定機構の解明と化学免疫併用療法への応用
- Principal Investigator
  
  植松美影 (濱田美影)
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  The University of Tokyo
Treatment of metastatic tumors by systemic injection of tumor-retargeted oncolytic herpesviruses
- Principal Investigator
  
  Uchida Hiroaki
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  The University of Tokyo
Development of oncolytic herpes simplex virus vectors retargeted to hematological malignancies
- Principal Investigator
  
  Uchida Hiroaki
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  The University of Tokyo
Molecular mechanism of chemotherapy-induced immunosuppressive proteins expressions in esophageal cancer cells.
- Principal Investigator
  
  Mika Hamada-Uematsu
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  The University of Tokyo
Development of cancer immunotherapy using hyperfusogenic receptor-retargeted HSVPrincipal Investigator
- Principal Investigator
  
  TAHARA HIDEAKI
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General surgery
- Research Institution
  The University of Tokyo
Development of highly specific oncolytic herpes virus vectors by modification of two envelope glycoproteins
- Principal Investigator
  
  Uchida Hiroaki
- Project Period (FY)
  2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Virology
- Research Institution
  The University of Tokyo
T細胞不活化制御による癌に対する遺伝子細胞療法の開発
- Principal Investigator
  
  松下まりも (佐藤まりも / 佐藤まりも / 松下まりも(佐藤まりも))
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  The University of Tokyo
Augmentation of tumor specificity and killing activity of oncolytic herpes virus vectors
- Principal Investigator
  
  Uchida Hiroaki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor therapeutics
- Research Institution
  The University of Tokyo
  Tokyo University of Pharmacy and Life Science
Development of quality prediction / rationalization system in autologous cell therapy which can conquer individual difference
- Principal Investigator
  
  KATANO HISAKO
- Project Period (FY)
  2010 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  The University of Tokyo
Preclinical Development of Cellular Gene therapy using Viral VectorPrincipal Investigator
- Principal Investigator
  
  TAHARA Hideaki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General surgery
- Research Institution
  The University of Tokyo
Multidiciplinary TNF・a based gene therapy using polyplex micelle
- Principal Investigator
  
  NAKA Nokenjl
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
Development of tumor-specific immunotherapy based on the analysis of functions of dendritic cellsPrincipal Investigator
- Principal Investigator
  
  TAHARA Hideaki
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
The development of the quality evaluation system of gene-modified dendritic cells for cancer immunotherapy and gene therapy
- Principal Investigator
  
  KATANO Hisako
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  The University of Tokyo
樹状細胞機能の理解に基づく腫瘍特異的免疫誘導法の開発Principal Investigator
- Principal Investigator
  
  田原秀晃
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
New Treatment for Age-related Macular Degeneration Antiangiogenic Thereapy using Nanotechnology and Retianl Regenerative Therapy
- Principal Investigator
  
  TAMAKI Yasuhiro
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Ophthalmology
- Research Institution
  The University of Tokyo
Development of the PKR-dependent replicating adenovirus
- Principal Investigator
  
  SASAKI Katsunori
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  The University of Tokyo
Novel gene therapy by modulation of dendritic cells in vivo
- Principal Investigator
  
  TAKUYA Takayama
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Japanese Foundation For Cancer Research
Analysis of the impact of Conflict of Interest on the determination of the patients and the patients right
- Principal Investigator
  
  NAGAMURA Fumitaka
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  医療における生命倫理
- Research Institution
  The University of Tokyo
樹状細胞機能の理解に基づく腫瘍特異的免疫誘導法の開発Principal Investigator
- Principal Investigator
  
  田原秀晃
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Development of cancer immune-gene therapy using viral vector produced in Japanese academiaPrincipal Investigator
- Principal Investigator
  
  TAHARA Hideaki
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General surgery
- Research Institution
  The University of Tokyo
Systemic disposition and induction of antitumor immunity with murine gene-modified dendritic cells
- Principal Investigator
  
  KATANO Hisako
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  The University of Tokyo
The role of CD4+CD25+T cells for immunological tolerance induction in organ transplantation
- Principal Investigator
  
  BECK Yoshifumi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  The University of Tokyo
Development for new cancer vaccine against heterogenicity and HLA-loss of tumor
- Principal Investigator
  
  TSUNODA Takuya
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  The University of Tokyo
NEW DEVELOPMENT OF DC IMMUNOTHERAPY TO UNIDENTIFIED CANCER ANTIGEN
- Principal Investigator
  
  TAKAYAMA Takuya
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  The University of Tokyo
非特異的免疫機構を利用した腫瘍特異的免疫の誘導Principal Investigator
- Principal Investigator
  
  田原秀晃
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Clinical development of cancer gene therapy using viral vectorsPrincipal Investigator
- Principal Investigator
  
  TAHARA Hideaki
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General surgery
- Research Institution
  The University of Tokyo
Analysis of tolerance induction using immunosuppresslve dendritic cells in transplantation
- Principal Investigator
  
  BECK Yoshifumi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  The University of Tokyo
Cancer treatment by non-myeloablative hematopoietic stem cell transplant with Flt3L gene transfection.
- Principal Investigator
  
  ANDO Yuichi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  The University of Tokyo
Development for new cancer vaccine using various kinds of epitope peptides
- Principal Investigator
  
  TSUNODA Takuya
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  The University of Tokyo
非特異的免疫機構を利用した包括的な腫瘍特異的免疫治療の開発Principal Investigator
- Principal Investigator
  
  田原秀晃
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
臨床応用可能なウイルスベクター製造のための企画調査
- Principal Investigator
  
  ICHIKAWA Naoya
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  The University of Tokyo
Development of gene therapy using chemokine that regulates the mobilization of dendritic cells in situ
- Principal Investigator
  
  TAKAYAMA Takuya
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  The University of Tokyo
臨床用遺伝子導入ベクター開発を目的としたコモンマーモセット前臨床動物系の確立
- Principal Investigator
  
  TANI Kenzaburou
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
  The University of Tokyo
遺伝子治療用インテリジェント・リポソームシステムの開発
- Principal Investigator
  
  柳衛宏宣
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Teikyo University
  The University of Tokyo
Adjuvant immuno-gene therapy for surgical treatment using dendritic cellsPrincipal Investigator
- Principal Investigator
  
  TAHARA Hideaki
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  The University of Tokyo
Evaluation of in vivo tolerogenicity of genetically modified recipient dendritic cells (syngeneic DC) pulsed with immunogenic peptides (allopeptides) derived from donor HLA molecule in HLA class I transgenic mouse.
- Principal Investigator
  
  BECK Yoshifumi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  The University of Tokyo.
Basic study for. Cancer Gene Therapy by Antitumor Effects Using Fas-Fas Ligand-Mediated Apoptosis
- Principal Investigator
  
  TAKEDA Yasutaka
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  The University of Tokyo
Gene therapy for cancer using intratumoral injection of dendritic cells genetically modified to express interleukin 12
- Principal Investigator
  
  ICHIKAWA Naoya
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  The University of Tokyo

[Journal Article] Potent anti-tumor effects of receptor-retargeted syncytial oncolytic herpes simplex virus2021
- Author(s)
  Suzuki Takuma、Uchida Hiroaki、Shibata Tomoko、Sasaki Yasuhiko、Ikeda Hitomi、Hamada-Uematsu Mika、Hamasaki Ryota、Okuda Kosaku、Yanagi Shigeru、Tahara Hideaki
- Journal Title
  
  Molecular Therapy - Oncolytics
  
  Volume: 22 Pages: 265-276
- DOI
  10.1016/j.omto.2021.08.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07319
[Journal Article] Antibody Screening System Using a Herpes Simplex Virus (HSV)-Based Probe To Identify a Novel Target for Receptor-Retargeted Oncolytic HSVs2021
- Author(s)
  Hitomi Ikeda, Hiroaki Uchida, Yu Okubo, Tomoko Shibata, Yasuhiko Sasaki, Takuma Suzuki, Mika Hamada -Uematsu, Ryota Hamasaki, Kosaku Okuda, Miki Yamaguchi, Masaki Kojima, Masato Tanaka, Hirofumi Hamada, Hideaki Tahara
- Journal Title
  
  Journal of Virology
  
  Volume: 95
- DOI
  10.1128/jvi.01766-20
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07319, KAKENHI-PROJECT-18H02687
[Journal Article] NK cells control tumor-promoting function of neutrophils in mice.2018
- Author(s)
  Ogura K, Sato-Matsushita M, Yamamoto S, Hori T, Sasahara M, Iwakura Y, Saiki I, Tahara H, Hayakawa Y.
- Journal Title
  
  Cancer Immunology Research
  
  Volume: in press
- NAID
  120006402039
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H01578
[Journal Article] Immuno-regulatory influence of abundant MFG-E8 expression by esophageal cancer treated with chemotherapy.2018
- Author(s)
  Kanemura Takashi、Miyata Hiroshi、Makino Tomoki、Tanaka Koji、Sugimura Keijiro、Hamada-Uematsu Mika、Mizote Yu、Uchida Hiroaki、Miyazaki Yasuhiro、Takahashi Tsuyoshi、Kurokawa Yukinori、Yamasaki Makoto、Wada Hisashi、Nakajima Kiyokazu、Takiguchi Shuji、Mori Masaki、Doki Yuichiro、Tahara Hideaki
- Journal Title
  
  Cancer Science
  
  Volume: 109 Pages: 224-228
- DOI
  10.1111/cas.13785
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07319, KAKENHI-PROJECT-17H01578
[Journal Article] Chimeric Anti-Human Podoplanin Antibody NZ-12 of Lambda Light Chain Exerts Higher Antibody-Dependent Cellular Cytotoxicity and Complement-Dependent Cytotoxicity Compared with NZ-8 of Kappa Light Chain2017
- Author(s)
  Kaneko MK, Abe S, Ogasawara S, Fujii Y, Yamada S, Murata T, Uchida H, Tahara H, Nishioka Y, Kato Y.
- Journal Title
  
  Monoclon Antib Immunodiagn Immunothe
  
  Volume: 36(1) Pages: 25-29
- DOI
  10.1089/mab.2016.0047
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26440019, KAKENHI-PROJECT-17H01578, KAKENHI-PROJECT-16H05309
[Journal Article] Cytokine biomarkers to predict antitumor responses to nivolumab suggested in a phase 2 study for advanced melanoma2017
- Author(s)
  Yamazaki Naoya、Kiyohara Yoshio、Uhara Hisashi、Iizuka Hajime、Uehara Jiro、Otsuka Fujio、Fujisawa Yasuhiro、Takenouchi Tatsuya、Isei Taiki、Iwatsuki Keiji、Uchi Hiroshi、Ihn Hironobu、Minami Hironobu、Tahara Hideaki
- Journal Title
  
  Cancer Science
  
  Volume: 108 Pages: 1022-1031
- DOI
  10.1111/cas.13226
- NAID
  120006373754
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10165, KAKENHI-PROJECT-17H01578
[Journal Article] Antiglycopeptide Mouse Monoclonal Antibody LpMab-21 Exerts Antitumor Activity Against Human Podoplanin Through Antibody-Dependent Cellular Cytotoxicity and Complement-Dependent Cytotoxicity2017
- Author(s)
  Kato Y, Kunita A, Fukayama M, Abe S, Nishioka Y, Uchida H, Tahara H, Yamada S,Yanaka M, Nakamura T, Saidoh N, Yoshida K, Fujii Y, Honma R, Takagi M, Ogasawara S, Murata T, Kaneko MK.
- Journal Title
  
  Monoclon Antib Immunodiagn Immunother
  
  Volume: 36(1) Pages: 20-24
- DOI
  10.1089/mab.2016.0045
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26440019, KAKENHI-PROJECT-17H01578, KAKENHI-PROJECT-16H05309, KAKENHI-PROJECT-15K10459
[Journal Article] Development of an oncolytic HSV vector fully retargeted specifically to cellular EpCAM for virus entry and cell-to-cell spread.2016
- Author(s)
  Shibata T, Uchida H, Shiroyama T, Okubo Y, Suzuki T, Ikeda H, Yamaguchi M, Miyagawa Y, Fukuhara T, Cohen JB, Glorioso JC, Watabe T, Hamada H, Tahara H.
- Journal Title
  
  Gene Therapy
  
  Volume: 印刷中 Pages: 479-488
- DOI
  10.1038/gt.2016.17
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15144, KAKENHI-PROJECT-25290059, KAKENHI-PROJECT-15K06876, KAKENHI-PROJECT-16K08249, KAKENHI-PROJECT-16K07184
[Journal Article] 大腸癌の遺伝子治療・ウイルス療法2015
- Author(s)
  内田宏昭, 田原秀晃
- Journal Title
  
  日本臨床
  
  Volume: 1077 Pages: 569-573
- Data Source
  KAKENHI-PROJECT-25290059
[Journal Article] 大腸癌の遺伝子治療・ウイルス療法2015
- Author(s)
  内田宏昭, 田原秀晃
- Journal Title
  
  日本臨床
  
  Volume: 1077 Pages: 569-573
- Data Source
  KAKENHI-PROJECT-15K15144
[Journal Article] TLR3/TICAM-1 signaling converts tumor-supporting myeloid cells to tumoricidal Effectors2012
- Author(s)
  H.Shime
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 109 Pages: 2066-2071
- DOI
  10.1073/pnas.1113099109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009, KAKENHI-PROJECT-21200079, KAKENHI-PROJECT-21249069, KAKENHI-PROJECT-21590326, KAKENHI-PUBLICLY-22021002, KAKENHI-PLANNED-22114008, KAKENHI-PUBLICLY-22117501, KAKENHI-PROJECT-22790371, KAKENHI-PROJECT-22790450, KAKENHI-PROJECT-23390120, KAKENHI-PROJECT-23590558, KAKENHI-PROJECT-24590470, KAKENHI-PROJECT-24659214
[Journal Article] Early activation and IFN-γproduction of tumor infiltrating mature CD27high NK cells2011
- Author(s)
  Y.Hayakawa
- Journal Title
  
  Cancer Sci.
  
  Volume: 102 Pages: 1967-1971
- DOI
  10.1111/j.1349-7006.2011.02042.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009, KAKENHI-PROJECT-21249069, KAKENHI-PROJECT-22659016, KAKENHI-PUBLICLY-23112519, KAKENHI-PROJECT-23300355, KAKENHI-PROJECT-23701073
[Journal Article] Tumor-associated macrophages regulate tumorigenicity and anticancer drugresponses of cancer stem/initiating cells2011
- Author(s)
  Jinushi M, Chiba S, Yoshiyama H, Masutomi K, Kinoshita I, Dosaka-Akita H, Yagita H, Takaoka A, Tahara H.
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 108巻 Pages: 112425-12430
- DOI
  10.1073/pnas.1106645108
- NAID
  10030575946
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249069, KAKENHI-PROJECT-21689031, KAKENHI-PROJECT-22240089, KAKENHI-PUBLICLY-23130501, KAKENHI-PROJECT-23590534, KAKENHI-PROJECT-23591132
[Journal Article] MicroRNA-based gene regulation of glycoprotein B5R in oncolytic vaccinia virus reduces viral pathogenicity without impairing its antitumor2011
- Author(s)
  Hikichi M, Kidokoro M, Haraguchi T, Iba H, Shida H, Tahara H & Nakamura T.
- Journal Title
  
  Molecular Therapy
  
  Volume: 19巻 Pages: 1107-1115
- DOI
  10.1038/mt.2011.36
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249069, KAKENHI-PROJECT-22659227, KAKENHI-PROJECT-22680065, KAKENHI-PROJECT-22700873, KAKENHI-PUBLICLY-23130504
[Journal Article] Proatherogenic effect of interleukin-18 is exerted with high-fat diet, but not with normal diet in spontaneously hyperlipidemic mice2011
- Author(s)
  Imai T, Oikawa Y, Shimada A, Oguchi S, Takamiya Y, Katsuki T, Okubo Y, Osaki T, Tahara H, Matsushima Y, Miyazaki J, Itoh H
- Journal Title
  
  J Atheroscler Throimb
  
  Volume: 18 Pages: 1090-101
- NAID
  130004845359
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249069
[Journal Article] Mechanism of HSV infection through soluble adapter-mediated virus bridging to the EGF receptor2011
- Author(s)
  Nakano K, Kobayashi M, Nakamura K, Nakanishi T, Asano R, Kumagai I, Tahara H, Kuwano M, Cohene JB, Glorioso JC
- Journal Title
  
  Virology
  
  Volume: 413 Pages: 2-18
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249069
[Journal Article] Cohen IB2011
- Author(s)
  Nakano K, Kobayashi M, Nakamura K, Nakanishi T, Asa no R, Kumagai 1, Tahara H, Kuwano
- Journal Title
  
  Glorioso JC : Mechanism of HSV infection through soluble adapter-mediated virus bridging to the EGF receptor
  
  Volume: 413(1) Pages: 12-18
- Data Source
  KAKENHI-PROJECT-21390374
[Journal Article] Ex-vivo expanded DC induce donor-specific central and peripheral tolerance and prolong the acceptance of donor skin allografts.2011
- Author(s)
  Yamano T, Watanabe S, Hasegawa H, Suzuki T, Abe R, Tahara H, Nitta T, Ishimaru N, Sprent J, Kishimoto H.
- Journal Title
  
  Blood
  
  Volume: (in press)(掲載確定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249069
[Journal Article] Mechanism of HSV infection through soluble adapter-mediated virus bridging to the EGF receptor2011
- Author(s)
  Nakano K, Kobayashi M, Nakamura K, Nakanishi T, Asano R, Kumagai I, Tahara H, Kuwano M, Cohen JB, Glorioso JC
- Journal Title
  
  Virology
  
  Volume: 413 Pages: 12-18
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390374
[Journal Article] Mechanism of HSV infection through soluble adapter-mediated virus bridging to the EGF receptor2011
- Author(s)
  Nakano K, Kobayashi M, Nakamura K, Nakanishi T, Asano R, Kumagai I, Tahara H, Kuwano M, Cohene JB, Glorioso JC.
- Journal Title
  
  Virology
  
  Volume: 413巻 Pages: 12-18
- DOI
  10.1016/j.virol.2011.02.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249069, KAKENHI-PROJECT-22226013, KAKENHI-PROJECT-23686118
[Journal Article] MicroRNA regulation of vaccinia virus for enhanced oncolytic activity and reduced pathogenicity in oncolytic virotherapy2011
- Author(s)
  Hikichi M, Kidokoro M, Haraguchi T, Iba H, Shida H, Tahara H, Nakamura T.
- Journal Title
  
  Molecular Therapy
  
  Volume: (In press)(掲載確定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249069
[Journal Article] Mechanism of HSV infection through soluble adapter-mediated virus bridging to the EGF receptor.2011
- Author(s)
  Nakano K, Kobayashi M, Nakamura K, Nakanishi T, Asano R, Kumagai I, Tahara H, Kuwano M, Cohene JB, Glorioso JC.
- Journal Title
  
  Virology
  
  Volume: 413 Pages: 2-18
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249069
[Journal Article] Proatherogenic Effect of Interleukin-18 is Exerted with High-fat Diet, but not with Normal Diet in Spontaneously Hyperlipidemic Mice2011
- Author(s)
  Imai T, Oikawa Y, Shimada A, Oguchi S, Takamiya Y, Katsuki T, Okubo Y, Osaki T, Tahara H, Matsushima Y, Miyazaki J, Itoh H.
- Journal Title
  
  J Atheroscler Thromb
  
  Volume: 18巻 Issue: 12 Pages: 1090-101
- DOI
  10.5551/jat.7567
- NAID
  130004845359
- ISSN
  1340-3478, 1880-3873
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249069
[Journal Article] Ex-vivo expanded DC induce donor-specific central and peripheral tolerance and prolong the acceptance of donor skin allografts2011
- Author(s)
  Takahama Y
- Journal Title
  
  Blood
  
  Volume: 118 Pages: 2380-2381
- DOI
  10.1182/blood-2010-07-293860
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19059010, KAKENHI-PROJECT-21249069, KAKENHI-PROJECT-23249025
[Journal Article] Phase I clinical trial of the vaccination for the patients with metastatic melanoma using gp100-derived epitope peptide restricted to HLA-A*24022010
- Author(s)
  Baba T, Sato-Matsushita M, Kanamoto A, Itoh A, Oyaizu N, Inoue Y, Kawakami Y, Tahara H
- Journal Title
  
  J Translational Medicine
  
  Volume: 8 Pages: 84-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249069
[Journal Article] Phase I clinical trial of the vaccination for the patients with metastatic melanoma using gp100-derived epitope peptide restricted to HLA-A* 24022010
- Author(s)
  Baba T, Sato-Matsushita M, Kanamoto A, Itoh A, Oyaizu N, Inoue Y, Kawakami Y, Tahara H.
- Journal Title
  
  J Translational Medicine
  
  Volume: 8巻 Pages: 84-95
- DOI
  10.1186/1479-5876-8-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249069
[Journal Article] Cytokine gene-mediated immunotherapy : Current status and future perspectives.2009
- Author(s)
  Jinushi M, Tahara H
- Journal Title
  
  Cancer Science 100
  
  Pages: 1389-1396
- NAID
  10027192998
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249069
[Journal Article] Emerging concepts in biomarker discovery ; The US-Japan workshop on immunological molecular markers in oncology2009
- Author(s)
  Tahara H, et al
- Journal Title
  
  Journal of Translational Medicine
  
  Volume: 7巻 Pages: 1389-1396
- DOI
  10.1186/1479-5876-7-45
- Data Source
  KAKENHI-PROJECT-21249069
[Journal Article] Milk Fat Globule EGF-8 blockade triggers tumor destruction through coordinated cell-autonomous and immune-mediated mechanisms.2009
- Author(s)
  Jinushi M, Sato M, Kanamoto A, Itoh A, Nagai S, Koyasu S, Dranoff G, Tahara H.
- Journal Title
  
  J Exp. Med. 206
  
  Pages: 1317-1326
- Data Source
  KAKENHI-PROJECT-20015016
[Journal Article] Cytokine gene-mediated immunotherapy : Current status and future perspectives2009
- Author(s)
  Jinushi M, Tahara H
- Journal Title
  
  Cancer Science
  
  Volume: 100巻 Pages: 1389-1396
- DOI
  10.1111/j.1349-7006.2009.01202.x
- NAID
  10027192998
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249069
[Journal Article] Emerging concepts in biomarker discovery2009
- Author(s)
  Tahara H., et, al
- Journal Title
  
  J Translational Med 7
  
  Pages: 45-69
- Data Source
  KAKENHI-PROJECT-20015016
[Journal Article] Cytokine gene-mediated immunotherapy: Current status and future perspectives.2009
- Author(s)
  Jinushi M, Tahara H
- Journal Title
  
  Cancer Science 100
  
  Pages: 1389-1396
- NAID
  10027192998
- Data Source
  KAKENHI-PROJECT-20015016
[Journal Article] Emerging concepts in biomarker discovery ; The US-Japan workshop on immunological molecular markers in oncology2009
- Author(s)
  Tahara H., et al.(56 authors in total)
- Journal Title
  
  Journal of Translational Medicine 7
  
  Pages: 45-69
- Data Source
  KAKENHI-PROJECT-21249069
[Journal Article] Milk-fat globule EGF-8 triggers tumor destruction through coordinated cell-autonomous and immune-mediated mechanisms2009
- Author(s)
  Jinushi M, Sato M, Kanamoto A, Itoh A, Nagai S, Koyasu S, Dranoff G, and Tahara H.
- Journal Title
  
  J. Exp. Med.
  
  Volume: 100巻 Pages: 1317-1326
- DOI
  10.1084/jem.20082614
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249069, KAKENHI-PROJECT-21689031
[Journal Article] Emerging concepts in biomarker discovery ; The US-Japan workshop on immunological molecular markers in oncology2009
- Author(s)
  Tahara H., et al.(56 authors in total)
- Journal Title
  
  Journal of Translational Medicine 7
  
  Pages: 45-69
- Data Source
  KAKENHI-PROJECT-20015016
[Journal Article] Cytokine gene-mediated immunotherapy : Current status and future perspe dives2009
- Author(s)
  Jinushi M, Tahara H.
- Journal Title
  
  Cancer Science 100
  
  Pages: 1389-1396
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015016
[Journal Article] Milk Fat Globule EGF-8 blockade triggers tumor destruction through coordinated cell-autonomous and immune-mediated mechanisms.2009
- Author(s)
  Jinushi M, Sato M, Kanamoto A, Itoh A, Nagai S, Koyasu S, Dranoff G, Tahara H.
- Journal Title
  
  Journal of Experimental Medicine 100
  
  Pages: 1389-1396
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249069
[Journal Article] Milk Fat Globule EGF-8 blockade triggers tumor destruction through coor dinated cell-autonomous and immune-mediated mechanisms2009
- Author(s)
  Jinushi M, Sato M, Kanamoto A, Itoh A, Nagai S, Koyasu S, Dranoff G, Tahara H.
- Journal Title
  
  Journal of Experimental Medicine 100
  
  Pages: 1389-1396
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015016
[Journal Article] Identification of human leukocyte antigen-A24-restricted epitope peptides derived from gene products upregulated in lung and esophageal cancers as novel targets for immunotherapy.2008
- Author(s)
  Suda T, Tahara H, et. al.
- Journal Title
  
  Cancer Sci(掲載確実)
- NAID
  10020119420
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18612002
[Journal Article] Vaccination with epitope peptide derived from human VEGF receptor 2 prevent choroidal neovascularization in an animal model2008
- Author(s)
  Takahashi H, Tahara H, et. al.
- Journal Title
  
  Investigative Ophthalmology & Vis Science (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18612002
[Journal Article] Vaccination with epitope peptide derived from human VEGF receptor 2 prevent choroidal neovascularization in an animal model.2008
- Author(s)
  Takahashi H, Tahara H, et. al.
- Journal Title
  
  Investigative Ophthalmology & Visual Science(掲載確実)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18612002
[Journal Article] 「研究成果報告書概要(欧文)」より2008
- Author(s)
  Saito T, Takayama T, Osaki T, Nagai S, Suzuki T, Sato M, Kuwano H, Tahara H
- Journal Title
  
  Cancer Sci. 99
  
  Pages: 2028-36
- Data Source
  KAKENHI-PROJECT-17209042
[Journal Article] Identification of human leukocyte antigen-A24-restricted epitope peputides derived from gene products upregulated in lung and esophageal vancers as novel targets for immunology.2008
- Author(s)
  Suda T., Tahara H., et. al.
- Journal Title
  
  Cancer Sci 9(掲載確定)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18612002
[Journal Article] Identification of human leukocyte antigen-A24-restricted epitope peptides derived from gene products upregulated in lung and esophageal cancers as novel targets for immunotherapy.2008
- Author(s)
  Suda T, Tahara H, et. al.
- Journal Title
  
  Cancer Sci (掲載確実)
- NAID
  10020119420
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18612002
[Journal Article] Combined mobilization and stimulation of tumor-infiltrating dendritic cells and natural killer cells with Flt3 ligand and IL-18 in vivo induces systemic anti-tumor immunity2008
- Author(s)
  Saito T, Takayama T, Osaki T, Nagai S, Suzuki T, Sato M, Kuwano H, Tahara H.
- Journal Title
  
  Cancer Science 99
  
  Pages: 2028-2036
- NAID
  10024012190
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015016
[Journal Article] 「研究成果報告書概要(欧文)」より2008
- Author(s)
  Suzuki T, Ogawa S, Tanabe K, Tahara H, Abe R, Kishimoto H
- Journal Title
  
  J Immunol 180
  
  Pages: 4596-4605
- Data Source
  KAKENHI-PROJECT-17209042
[Journal Article] Suppression of choroidal neovascularization by vaccination with epitope peptide derived from human VEGF receptor 2 in an animal model.2008
- Author(s)
  Takahashi H, Ishizaki H, Tahara H, Tamaki Y, Yanagi Y.
- Journal Title
  
  Investigtive Ophthalmology & Visual Science 49
  
  Pages: 2143-2147
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390465
[Journal Article] Identification of human leukocyte antigen-A24-restricted epitope peptides derived from gene products upregulated in lung and esophageal cancers as novel targets for immunotherapy2008
- Author(s)
  Suda T, Tahara H, et. al.
- Journal Title
  
  Cancer Sci (in press)
- NAID
  10020119420
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18612002
[Journal Article] Vaccination with Epitope Peptide Derived from Human VEGF Receptor 2 Prevent Choroidal Neovascularization in an Animal Model.2008
- Author(s)
  Takahashi H, Ishizaki H, Tahara H, Tamaki Y, Yanagi Y.
- Journal Title
  
  Investigative Ophthalmology & Visual Science 49
  
  Pages: 2143-2147
- Data Source
  KAKENHI-PROJECT-20015016
[Journal Article] Suppression of choroidal neovascularization by vaccination with epitope peptide derived from hu2008
- Author(s)
  Takahashi H, IshizakiH, TaharaH, Tamak
- Journal Title
  
  Investigtive Ophthalmology & Visual Science 49
  
  Pages: 2143-2147
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390465
[Journal Article] Suppression of choroidal neovascularization by vaccination with epitope peptide derived from human VEGF receptor 2 in an animal model.2008
- Author(s)
  Takahashi H. Ishizaki H, Tahara H. Tamaki Y. Yanagi Y.
- Journal Title
  
  Investigtive Ophthalmology & Visual Science 49
  
  Pages: 2143-2147
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390465
[Journal Article] Combined mobilization and stimulation of tumor-infiltrating dendritic cells and natural killer cells with Flt3 ligand and IL-18 in vivo induces systemic anti-tumor immunity.2008
- Author(s)
  Saito T, Takayama T, Osaki T, Nagai S, Suzuki T, Sato M, Kuwano H, Tahara H.
- Journal Title
  
  Cancer Sci. 99
  
  Pages: 2028-36
- NAID
  10024012190
- Data Source
  KAKENHI-PROJECT-20015016
[Journal Article] Induction of anti-tumor immune response by homeostatic proliferation and CD28 signaling.2008
- Author(s)
  Suzuki T, Ogawa S, Tanabe K, Tahara H, Abe R, Kishimoto H.
- Journal Title
  
  J Immunol 180
  
  Pages: 4596-4605
- Data Source
  KAKENHI-PROJECT-20015016
[Journal Article] Induction of and-tumor immune response by homeostatic prolifer ation and CD28 sianalina2008
- Author(s)
  Suzuki T, Ogawa S, Tanabe K, Tahara H. Abe R.Kishimoto H
- Journal Title
  
  J Immunology 180
  
  Pages: 4596-4605
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015016
[Journal Article] Induction of anti-tumor immune response by homeostatic proliferation and CD28 signaling.2008
- Author(s)
  Suzuki T, Ogawa S, Tanabe K, Tahara H, Abe R, Kishimoto H.
- Journal Title
  
  J Immunology 180
  
  Pages: 4596-4605
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209042
[Journal Article] Identification of human leukocyte antigen-A24-restricted epitope peputides derived from gene products upregulated in lung and esophageal vancers as novel targets for immunology2008
- Author(s)
  Suda T., Tahara H., et. al.
- Journal Title
  
  Cancer Sci (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18612002
[Journal Article] Identification of human leukocyte antigen-A24-restricted epitope peputides derived from gene products upregulated in lung and esophageal vancers as novel targets for immunology.2008
- Author(s)
  Suda T., Tahara H., et. al.
- Journal Title
  
  Cancer Sci(掲載確実) 9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18612002
[Journal Article] Combined mobilization and stimulation of tumor-infiltrating dendritic cells and natural killer cells with Flt3 ligand and IL-18 in vivo induces systemic anti-tumor immunity.2008
- Author(s)
  Saito T, Takayama T, Osaki T, Nagai S, Suzuki T, Sato M, Kuwano H, Tahara H.
- Journal Title
  
  Cancer Science 99
  
  Pages: 2028-2036
- NAID
  10024012190
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209042
[Journal Article] Syastemic administration of IL23 induces potent antitumor immunity primary mediated through Th1-type response in association with the endogenously expressed IL-12.2007
- Author(s)
  Kaiga T, Tahara H, et. al.
- Journal Title
  
  J Immunol 178
  
  Pages: 751-80
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18612002
[Journal Article] Systemic Administration of IL-23 Induces Potent Anti-tumor Immunity Primarily Mediated through Th1-type Response in Association with the Endogeno usiy Expressed IL-12.2007
- Author(s)
  Kaiga T, Sato M, Kaneda H, Iwakura Y, Takayama T, Tahara H.
- Journal Title
  
  J Immunology 178
  
  Pages: 7571-80
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209042
[Journal Article] Systemic Administration of IL-23 Induces Potent Anti-tumor Immunity Primarily Mediated through Th1-type Response in Association with the Endogenously Expressed IL-122007
- Author(s)
  Kaiga T, Sato M, Kaneda H, Iwakura Y, Takayama T, Tahara H
- Journal Title
  
  J Immunol 178
  
  Pages: 7571-7580
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209042
[Journal Article] 「研究成果報告書概要(欧文)」より2007
- Author(s)
  Kaiga T, Sato M, Kaneda H, Iwakura Y, Takayama T, Tahara H
- Journal Title
  
  J Immunol 178
  
  Pages: 7571-7580
- Data Source
  KAKENHI-PROJECT-17209042
[Journal Article] Syastemic administration of IL23 induces potent antitumor immunity primary mediated through Th1-type response in association with the endogenously expressed IL-122007
- Author(s)
  Kaiga T, Tahara H, et. al.
- Journal Title
  
  J Immunol 178
  
  Pages: 751-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18612002
[Journal Article] Identification of HLA-A24-restricted epitope-peptides derived from gene products up-regulated in lung and esophageal cancers as novel targets for immunotherapy2007
- Author(s)
  Suda T, Tsunoda T, Daigo Y, Nakamura Y, Tahara H
- Journal Title
  
  Cancer Science 98
  
  Pages: 1803-1908
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209042
[Journal Article] Cancer gene therapy using in vivo electroporation of Flt3-Ligand.2005
- Author(s)
  Shimao K, Takayama T, Enomoto K, Saito T, Nagai S, Miyazaki J, Ogawa K, Tahara H.
- Journal Title
  
  Int.J Oncol. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591330
[Journal Article] Dendritic cell might be one of key factors for eliciting antitumor effect by chemo-immunotherapy in vivo.2005
- Author(s)
  Mushiake H, Tahara H.他6名
- Journal Title
  
  Cancer Immunology Immunotherapy (in press)
- Data Source
  KAKENHI-PROJECT-14030010
[Journal Article] Dendritic cell might be one of key factors for eliciting antitumor effect by chemo-immunotherapy in vivo.2005
- Author(s)
  Mushiake H, Tsunoda T, Nukatsuka M, Shimao K, Fukushima M, Tahara H.
- Journal Title
  
  Cancer Immunology Immunotherapy 54
  
  Pages: 120-128
- Data Source
  KAKENHI-PROJECT-17016025
[Journal Article] Cancer gene therapy using in vivo electroporation of Flt3-Ligand.2005
- Author(s)
  Shimao K, Takayama T, Enomoto K, Saito T, Nagai S, Miyazaki J, Ogawa K, Tahara H.
- Journal Title
  
  Int J Oncology 27
  
  Pages: 457-463
- Data Source
  KAKENHI-PROJECT-17209042
[Journal Article] Cancer gene therapy using in vivo electroporation of Flt3-Ligand.2005
- Author(s)
  Shimao K, Tahara H.他8名
- Journal Title
  
  Int J Oncology (in press)
- Data Source
  KAKENHI-PROJECT-14030010
[Journal Article] Dendritic cell might be one of key factors for eliciting antitumor effect by chemo-immunotherapy in vivo.2005
- Author(s)
  Mushiake H, Tsunoda T, Nukatsuka M, Shimao K, Fukushima M, Tahara H.
- Journal Title
  
  Cancer Immunology Immunotherapy 54
  
  Pages: 120-128
- Data Source
  KAKENHI-PROJECT-17209042
[Journal Article] Cancer gene therapy using in vivo electroporation of Flt3-Ligand.2005
- Author(s)
  Shimao K, Takayama T, Enomoto K, Saito T, Nagai S, Miyazaki J, Ogawa K, Tahara H.
- Journal Title
  
  Int J Oncology 27
  
  Pages: 457-463
- Data Source
  KAKENHI-PROJECT-17016025
[Journal Article] Adenovirus-mediated transfer of siRNA against survivin induced apoptosis and attenuated tumor cell growth in vitro and in vivo.2004
- Author(s)
  Uchida H, Tahara H, 他9名
- Journal Title
  
  Mol Ther. 10
  
  Pages: 162-171
- Data Source
  KAKENHI-PROJECT-14030010
[Journal Article] Phase I study of autologous tumor vaccines transduced with the GM-CSF gene in four patients with stage IV renal cell cancer in Japan : clinical and immunological findings2004
- Author(s)
  Tani K, Tahara H, 他35名
- Journal Title
  
  Mol Ther. 10
  
  Pages: 799-816
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207047
[Journal Article] Adenoyirus-mediated transfer of siRNA against survivin induced appptosis and attenuated tumor cell growth in vitro and in vivo.2004
- Author(s)
  Uchida H, Tahara H, et al.
- Journal Title
  
  Mol Ther. 10
  
  Pages: 162-171
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207047
[Journal Article] Adenovirus-mediated transfer of siRNA against survivin induced apoptosis and attenuated tumor cell arowth in vitro and in vivo.2004
- Author(s)
  Uchida H, Tahara H, 他9名
- Journal Title
  
  Mol Ther. 10
  
  Pages: 162-171
- Data Source
  KAKENHI-PROJECT-14207047
[Journal Article] Adenovirus-mediated transfer of siRNA against survivin induced apoptosis and attenuated tumor cell growth in vitro and in vivo.2004
- Author(s)
  Uchida H, Tahara H, 他9名
- Journal Title
  
  Mol Ther. 10
  
  Pages: 162-171
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207047
[Journal Article] Generation of Mature Dendritic Cells Fully Capable of T Helper Type 1 Polarization Using OK-432 Combined with Prostaglandin E2.2004
- Author(s)
  Sato M, Tahara H.他2名
- Journal Title
  
  Cancer Science 94
  
  Pages: 1091-1098
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207047
[Journal Article] Phase I study of autologous tumor vaccines transduced with the GM-CSF gene in four patients with stage IV renal cell cancer in Japan : clinical and immunological findings.2004
- Author(s)
  Tani K, Tahara H, et al.
- Journal Title
  
  Mol Ther. 10
  
  Pages: 799-816
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207047
[Journal Article] Ring finger protein (RNF) 43 as a New Target for Cancer Immunotherapy Clinical2004
- Author(s)
  Uchida N, Tahara H.他6名
- Journal Title
  
  Cancer Research 10
  
  Pages: 8577-8586
- Data Source
  KAKENHI-PROJECT-14030010
[Journal Article] Phase I study of autologous tumor vaccines transduced with the GM-CSF gene in four patients with stage IV renal cell cancer in Japan : clinical and immunological findings2004
- Author(s)
  Tani K, Tahara H, 他35名
- Journal Title
  
  Mol Ther. 10
  
  Pages: 799-816
- Data Source
  KAKENHI-PROJECT-14030010
[Journal Article] Phase I study of autologous tumor vaccines transduced with the GM-C SF gene in four patients with stage IV renal cell cancer in Japan : clinical and immunological finding2004
- Author(s)
  Tani K, Tahara H, 他35名
- Journal Title
  
  Mol Ther. 10
  
  Pages: 799-816
- Data Source
  KAKENHI-PROJECT-14207047
[Journal Article] Dendritic cells stimulated with a bacterial product, OK-432, efficiently induce cytotoxic T lymphocytes specific to tumor rejection peptide.2003
- Author(s)
  Nakahara S, Tahara H.他3名
- Journal Title
  
  Cancer Research 63
  
  Pages: 4112-4118
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207047
[Journal Article] Dendritic cells stimulated with a bacterial product, OK-432,efficiently induce cytotoxic T lymphocytes specific to tumor rejection peptide.2003
- Author(s)
  Nakahara S, Tahara H, et al.
- Journal Title
  
  Cancer Research 63
  
  Pages: 4112-4118
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207047
[Journal Article] Hydrodynamics-based delivery of the viral interleukin-10 genesuppressesexperimental crescentic glomerulonephritis in Wistar-Kyoto rats.2003
- Author(s)
  Higuchi N, Tahara H, et al.
- Journal Title
  
  Gene Ther. 10
  
  Pages: 1297-1310
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207047
[Journal Article] Differential effects of IL-12 on the generation of alloreactive CTL mediated by murine and human dendritic cells : a critical role for nitric oxide.2003
- Author(s)
  Nishioka Y, Tahara H, et al.
- Journal Title
  
  J Leukoc Biol 73
  
  Pages: 621-629
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207047
[Journal Article] Interleukin-17 promotes angiogenesis and tumor growth.2003
- Author(s)
  Numasaki M.Tahara H, et al.
- Journal Title
  
  Blood 101
  
  Pages: 2620-2627
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207047
[Journal Article] NK but not NKT cells play a necessary role to promote an innate antitumor response induced by IL-18.2003
- Author(s)
  Hashimoto W, Tahara H.他5名
- Journal Title
  
  Int J Cancer 103
  
  Pages: 508-513
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207047
[Journal Article] Generation of Mature Dendritic Cells Fully Capable of T Helper Type 1 Polarization Using OK-432 Combined with Prostaglandin E2.2003
- Author(s)
  Sato M, Tahara H, et al.
- Journal Title
  
  Cancer Science 94
  
  Pages: 1091-1098
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207047
[Journal Article] Generation of Mature Dendritic Cells Fully Capable of T Helper Type 1 Polarization Using OK-432 Combined with Prostaglandin E2.2003
- Author(s)
  Sato M, Takayama T, Tanaka H, Konishi J, Suzuki T, Kaiga T, Tahara H.
- Journal Title
  
  Cancer Sci 94
  
  Pages: 1091-1098
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591330
[Journal Article] Interleukin-17 promotes angiogenesis and tumor growth.2003
- Author(s)
  Numasaki M, Tahara H.他7名
- Journal Title
  
  Blood 101
  
  Pages: 2620-2627
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207047
[Journal Article] NK but not NKT cells play a necessary role to promote an innate antitumor response induced by IL-18.2003
- Author(s)
  Hashimoto W, Tahara H, et al.
- Journal Title
  
  Int J Cancer 103
  
  Pages: 508-513
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207047
[Journal Article] Differential effects of IL-12 on the generation of alloreactive CTL mediated by murine and human dendritic cells : a critical role for nitric oxide.2003
- Author(s)
  Nishioka Y, Tahara H.他5名
- Journal Title
  
  J Leukoc Biol 73
  
  Pages: 621-629
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207047
[Journal Article] Hydrodynamics-based delivery of the viral interleukin-10 gene suppresses experimental crescentic glomerulonephritis in Wistar-Kyoto rats.2003
- Author(s)
  Higuchi N, Tahara H, 他9名
- Journal Title
  
  Gene Ther 10
  
  Pages: 1297-1310
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207047
[Journal Article] Retroviral delivery of transforming growth factor-β1 to myeloid dendritic cells ; inhibition of T cell priming ability and influence on allograft survival.2002
- Author(s)
  Takayama T, Tahara H.他4名
- Journal Title
  
  Transplantation 74
  
  Pages: 112-119
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207047
[Journal Article] Therapeutic and specific antitumor immunity induced by co-administration of immature dendritic cells and adenoviral vector expressing biologically active IL-18.2002
- Author(s)
  Tanaka F, Tahara H, et al.
- Journal Title
  
  Gene Ther 9
  
  Pages: 1480-1486
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207047
[Journal Article] Construction and Analysis of New Vector Systems with Improved Interleukin-18 Secretion in Xenogeneic Human Tumor Model2002
- Author(s)
  Goto H, Tahara H, et al.
- Journal Title
  
  J Immunother 25 Suppl 1
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207047
[Journal Article] Retroviral delivery of transforming growth factor-β 1 to myeloid dendritic cells ; inhibition of T cell priming ability and influence on allograft survival.2002
- Author(s)
  Takayama T, Tahara H, et al.
- Journal Title
  
  Transplantation 74
  
  Pages: 112-119
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207047
[Journal Article] Therapeutic and specific antitumor immunity induced by co-administration of immature dendritic cells and adenoviral vector expressing biologically active IL-18.2002
- Author(s)
  Tanaka F, Tahara H.他3名
- Journal Title
  
  Gene Ther 9
  
  Pages: 1480-1486
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207047
[Journal Article] Construction and Analysis of New Vector Systems with Improved Interleukin-18 Secretion in Xenogeneic Human Tumor Model2002
- Author(s)
  Goto H, Tahara H.他8名
- Journal Title
  
  J Immunother 25 Suppl 1
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207047
[Journal Article] Milk Fat Globule EGF-8 blockade triggers tumor destruction through coordinated cell-autonomous and immune-mediated mechanisms
- Author(s)
  inushi M, Sato M, Kanamoto A, Itoh A, Nagai S, Koyasu S, Dranoff G, and Tahara H
- Journal Title
  
  J Experimental Medicine (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015016
[Journal Article] Intrathymic Inoculation of Donor HLA Class-1 derived Peptide Generates Donor-Specific CD4+CD25+ regulatory T cells.
- Author(s)
  S.Tamura, Y.Beck, Y.Ando, H.Tahara
- Journal Title
  
  Transplantation Proc (In press)
- Data Source
  KAKENHI-PROJECT-16591248
[Journal Article] Syastemic administration of IL23 induces potent antitumor immunity primary mediated through Th1-type response in association with the endogenously expressed IL-12
- Author(s)
  Kaiga T, Tahara H, et. al.
- Journal Title
  
  J Immunol
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18612002
[Patent] がん治療のための腫瘍溶解性ウイルス2019
- Inventor(s)
  内田宏昭・田原秀晃
- Industrial Property Rights Holder
  内田宏昭・田原秀晃
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Overseas
- Data Source
  KAKENHI-PROJECT-18K19468
[Patent] がん治療のための腫瘍溶解性ウイルス2019
- Inventor(s)
  内田宏昭・田原秀晃
- Industrial Property Rights Holder
  内田宏昭・田原秀晃
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Overseas
- Data Source
  KAKENHI-PROJECT-18H02687
[Patent] 脈絡膜新生血管のワクチン療法2008
- Inventor(s)
  玉置泰裕, 田原秀晃
- Industrial Property Rights Holder
  東京大学
- Filing Date
  2008-02-15
- Description
  「研究成果報告書概要(和文)」より
- Overseas
- Data Source
  KAKENHI-PROJECT-18390465
[Patent] 脈絡膜新生血管のワクチン療法2008
- Inventor(s)
  玉置泰裕田原秀晃
- Industrial Property Rights Holder
  東京大学
- Filing Date
  2008-02-15
- Data Source
  KAKENHI-PROJECT-18390465
[Patent] 脈絡膜新生血管のワクチン療法2007
- Inventor(s)
  玉置泰裕、田原秀晃
- Industrial Property Rights Holder
  国立大学法人東京大学
- Filing Date
  2007-02-16
- Data Source
  KAKENHI-PROJECT-18390465
[Presentation] 患者検体を利用したがん治療開発システムの構築2019
- Author(s)
  田原秀晃
- Organizer
  第26回HAB研究機構学術年会
- Invited
- Data Source
  KAKENHI-PROJECT-17H01578
[Presentation] 患者検体の先進的利活用による医療の開発と検証2019
- Author(s)
  田原秀晃
- Organizer
  安全性評価研究会第２２回　春のセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-17H01578
[Presentation] 免疫応答のプライミング相を制御する新規がん治療法の開発2019
- Author(s)
  田原秀晃，溝手雄，他
- Organizer
  第 119 回日本外科学会定期学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17H01578
[Presentation] Time-scale analysis of interplay between occult immunogenic tumor and immune response2015
- Author(s)
  Marija Mojic, Marimo Sato-Matsushita, Hideaki Tahara, Ikuo Saiki, Yoshihiro Hayakawa
- Organizer
  第44回日本免疫学会学術集会
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-25461974
[Presentation] 腫瘍細胞表面抗原を介して侵入する標的化単純ヘルペスウイルスベクターの開発2015
- Author(s)
  城山智貴, 内田宏昭, 大久保優, 柴田智子, 福原武志, 山口美樹, Justus B. Cohen, Joseph C. Glorioso, 渡部徹郎, 濱田洋文, 田原秀晃
- Organizer
  第7回血液疾患免疫療法研究会
- Place of Presentation
  東京大学本郷キャンパス（東京都文京区）
- Year and Date
  2015-09-26
- Data Source
  KAKENHI-PROJECT-15K15144
[Presentation] Novel function of NK cell to regulate cancer-associated inflammation2015
- Author(s)
  小倉圭介、松下(佐藤) まりも、田原秀晃、済木育夫、早川芳弘
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25461974
[Presentation] 腫瘍細胞表面抗原を介して侵入する標的化単純ヘルペスウイルスベクターの開発2015
- Author(s)
  城山智貴, 内田宏昭, 大久保優, 柴田智子, 福原武志, 山口美樹, Justus B. Cohen, Joseph C. Glorioso, 渡部徹郎, 濱田洋文, 田原秀晃
- Organizer
  第7回血液疾患免疫療法研究会
- Place of Presentation
  東京大学本郷キャンパス（東京都文京区）
- Year and Date
  2015-09-26
- Data Source
  KAKENHI-PROJECT-25290059
[Presentation] Therapeutic efficacy of modified DC2014
- Author(s)
  Marimo Sato-Matsushita and Hideaki Tahara
- Organizer
  第24回日本樹状細胞研究会総会
- Place of Presentation
  山形
- Year and Date
  2014-06-20
- Invited
- Data Source
  KAKENHI-PROJECT-25461974
[Presentation] 癌免疫療法の現状と展望2011
- Author(s)
  田原秀晃
- Organizer
  第15回日本がん分子標的治療学会学術集会
- Place of Presentation
  ホテル日航東京(招待講演)
- Year and Date
  2011-06-24
- Data Source
  KAKENHI-PROJECT-21249069
[Presentation] 癌免疫療法の現状と展望(招待講演)2011
- Author(s)
  田原秀晃
- Organizer
  第15回日本がん分子標的治療学会学術集会
- Place of Presentation
  東京都
- Year and Date
  2011-06-24
- Data Source
  KAKENHI-PROJECT-21249069
[Presentation] Cancer vaccination using tumor cells in situ as the source of tumor antigens2010
- Author(s)
  Hideaki Tahara
- Organizer
  Working Group meeting(Invited Speaker)
- Place of Presentation
  米国NCI(Bethesda, MD)
- Year and Date
  2010-04-22
- Data Source
  KAKENHI-PROJECT-21249069
[Presentation] Significant enhancement of antigen-specific antitumor effects of DNA vaccine with systemic administration of interleukin-232010
- Author(s)
  米山公康、佐藤まりも、田原秀晃
- Organizer
  日本外科学会学術総会
- Place of Presentation
  名古屋市
- Year and Date
  2010-04-09
- Data Source
  KAKENHI-PROJECT-21249069
[Presentation] 生体内がんワクチン療法の開発2010
- Author(s)
  田原秀晃
- Organizer
  日本頭頸部癌学会(特別講演)
- Place of Presentation
  東京都
- Year and Date
  2010-06-10
- Data Source
  KAKENHI-PROJECT-21249069
[Presentation] Cancer vaccination using tumor cells in situ as the source of tumor antigens2010
- Author(s)
  Hideaki Tahara
- Organizer
  日本癌学会学術総会(シンポジウム)
- Place of Presentation
  大阪
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21249069
[Presentation] Cancer vaccination using tumor cells in situ as the source of tumor antigens2010
- Author(s)
  Hideaki Tahara
- Organizer
  日本癌学会学術総会(シンポジウム)
- Place of Presentation
  大阪、大阪国際会議場リーガロイヤルホテル大阪
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21249069
[Presentation] Cancer vaccination using tumor cells in situ as the source of tumor antigens2010
- Author(s)
  田原秀晃
- Organizer
  13th Asia Pacific-International Molecular Biology Network (A-IMBN) Symposium (Invited Speaker)
- Place of Presentation
  Chinese Taipei
- Year and Date
  2010-11-14
- Data Source
  KAKENHI-PROJECT-21249069
[Presentation] Cancer vaccination using tumor cells in situ as the source of tumor antigens2010
- Author(s)
  Hideaki Tahara
- Organizer
  Vaccine Working Group meeting (Invited Speaker)
- Place of Presentation
  米国NCI (Bethesda, MD)
- Year and Date
  2010-04-22
- Data Source
  KAKENHI-PROJECT-21249069
[Presentation] 生体内がんワクチン療法の開発2010
- Author(s)
  田原秀晃
- Organizer
  日本頭頸部癌学会
- Place of Presentation
  ウインクあいち(特別講演)
- Year and Date
  2010-06-10
- Data Source
  KAKENHI-PROJECT-21249069
[Presentation] Cancer vaccination using tumor cells in situ as the source of tumor antigens2010
- Author(s)
  田原秀晃
- Organizer
  13th Asia Pacific-International Molecular Biology Network(A-IMBN) Symposium(Invited Speaker)
- Place of Presentation
  Chinese Taipei
- Year and Date
  2010-11-14
- Data Source
  KAKENHI-PROJECT-21249069
[Presentation] 生体内に存在する腫瘍細胞を利用した癌免疫療法の開発2010
- Author(s)
  田原秀晃
- Organizer
  日本がん免疫学会(シンポジウム)
- Place of Presentation
  熊本市、リバーサイドホテル熊本
- Year and Date
  2010-07-23
- Data Source
  KAKENHI-PROJECT-21249069
[Presentation] Translational research of clinical dendritic cell therapy using OK-432 and prostaglandin E2(Phase I study)2010
- Author(s)
  Sato-Matsushita M, Kanamoto A, Katano H, Itoh A, Tahara H
- Organizer
  14^<th> International Congress of Immunology
- Place of Presentation
  神戸市、神戸ポートピアホテル神戸コンベンションセンター
- Year and Date
  2010-08-27
- Data Source
  KAKENHI-PROJECT-21249069
[Presentation] 生体内に存在する腫瘍細胞を利用した2010
- Author(s)
  田原秀晃
- Organizer
  癌免疫療法の開発日本がん免疫学会(シンポジウム)
- Place of Presentation
  熊本市
- Year and Date
  2010-07-23
- Data Source
  KAKENHI-PROJECT-21249069
[Presentation] Significant enhancement of antigen-specific antitumor effects of DNA vaccine with systemic administration of interleukin-232010
- Author(s)
  米山公康、佐藤まりも、田原秀晃
- Organizer
  日本外科学会学術総会
- Place of Presentation
  名古屋市、名古屋国際会議場
- Year and Date
  2010-04-09
- Data Source
  KAKENHI-PROJECT-21249069
[Presentation] Translational research of clinical dendritic cell therapy using OK-432 and prostaglandin E2(Phase I study)2010
- Author(s)
  Sato-Matsushita M, Kanamoto A, Katano H, Itoh A, Tahara H
- Organizer
  14^th International Congress of Immunology
- Place of Presentation
  神戸市
- Year and Date
  2010-08-27
- Data Source
  KAKENHI-PROJECT-21249069
[Presentation] Cancer vaccine against malignant melanoma using monocyte-derived dendritic cells stimulated with OK-432 and PGE22009
- Author(s)
  佐藤まりも、田原秀晃, 他5名
- Organizer
  日本癌学会総会
- Place of Presentation
  横浜市
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-20015016
[Presentation] Cancer vaccine against malignant melanoma using monocyte-derived dendritic cells stimulated with OK-432 and PGE22009
- Author(s)
  佐藤まりも、田原秀晃, 他5名
- Organizer
  日本癌学会総会
- Place of Presentation
  横浜市
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-21249069
[Presentation] Cancer vaccination using tumor cells in situ as the source of tumor antigens2009
- Author(s)
  田原秀晃
- Organizer
  日本癌学会総会
- Place of Presentation
  横浜市
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-21249069
[Presentation]2009
- Author(s)
  佐藤まりも, 金本彰, 地主将久, 片野尚子, 米山公康, 伊藤精彦, 田原秀晃
- Organizer
  第13回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-19591504
[Presentation] Cancer vaccine against malignant melanoma using monocyte-derived dendritic cells stimulated with OK-432 and PGE2009
- Author(s)
  佐藤まりも, 金本彰, 片野尚子, 地主将久, 米山公康, 伊藤精彦, 田原秀晃
- Organizer
  第68回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19591504
[Presentation] Antigen-specific antitumor effects of DNA vaccine are significantly enhanced with systemic administration of interleukin(IL)-232009
- Author(s)
  米山公康、田原秀晃, 他3名
- Organizer
  日本免疫学会総会
- Place of Presentation
  大阪市
- Year and Date
  2009-12-04
- Data Source
  KAKENHI-PROJECT-21249069
[Presentation] Antigen-specific antitumor effects of DNA vaccine are significantly enhanced with systemic administration of interleukin (IL)-232009
- Author(s)
  米山公康、田原秀晃, 他3名
- Organizer
  日本免疫学会総会
- Place of Presentation
  大阪市
- Year and Date
  2009-12-04
- Data Source
  KAKENHI-PROJECT-20015016
[Presentation] Cancer vaccination using tumor cells in situ as the source of tumor antigens2009
- Author(s)
  田原秀晃
- Organizer
  日本癌学会総会
- Place of Presentation
  横浜市
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-20015016
[Presentation] Clinical dendritic cell therapy using OK-432 and prostaglandin E2 (Phase I study)2009
- Author(s)
  佐藤まりも, 金本彰, 地主将久, 片野尚子, 米山公康, 伊藤精彦, 田原秀晃
- Organizer
  第19回日本樹状細胞研究会
- Data Source
  KAKENHI-PROJECT-19591504
[Presentation] Antigen-specific antitumor effects of DNA vaccine are significantly enhanced with systemic administration of interleukin(IL)-232009
- Author(s)
  米山公康、田原秀晃, 他3名
- Organizer
  日本免疫学会総会
- Place of Presentation
  大阪市
- Year and Date
  2009-12-04
- Data Source
  KAKENHI-PROJECT-20015016
[Presentation] Cancer vaccination using tumor cells in situ as the source of tumor antigens2009
- Author(s)
  田原秀晃
- Organizer
  (シンポジウム)日本癌学会総会
- Place of Presentation
  横浜市
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-20015016
[Presentation] Potent Anti-tumor Immunity and both Th1 and Th17 promotion associated with IL-23 administration (Symposium)2008
- Author(s)
  Hideaki Tahara
- Organizer
  Annual Meeting, International Society of Biological Therapy for Cancer
- Place of Presentation
  米国 San Diego
- Year and Date
  2008-10-31
- Data Source
  KAKENHI-PROJECT-20015016
[Presentation] Potent Anti-tumor Immunity and both Th1 and Th17 promotion associated with IL-23 administration (Symposium) Annual Meeting2008
- Author(s)
  Hideaki Tahara
- Organizer
  International Society of Biological Therapy for Cancer
- Place of Presentation
  米国San Diego
- Year and Date
  2008-10-31
- Data Source
  KAKENHI-PROJECT-20015016
[Presentation] PRODUCTION OF CURRENT GMP-COMPLIANT VIRAL VECTORS FOR EARLY PHASE CLINICAL TRIALS2007
- Author(s)
  Katsunori Sasaki, Hideaki Tahara, et. al.
- Organizer
  Japanese Society of Gene Therapy
- Place of Presentation
  Nagoya
- Year and Date
  2007-06-30
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209042
[Presentation] Potent anti-tumor effects of combination therapy using Interleukin-23 and alpha-galactosylceramide2007
- Author(s)
  Kaneda H., Tahara H., et. al.
- Organizer
  Annual Meeting of American Association of Cancer Research
- Place of Presentation
  USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18612002
[Presentation] Potent anti tumor effects of combination therapy using Interleukin-23 and alpha-galactosylceramide.2007
- Author(s)
  Kaneda H., Tahara H. et. al
- Organizer
  American Association of Cancer Research
- Place of Presentation
  USA
- Data Source
  KAKENHI-PROJECT-18612002
[Presentation] ESTABLISHMENT OF THE SYSTEM TO SUPPORT EX VTVO CELL MANIPULATION APPROPRIATE FOR CLINICAL TRIALS OF GENE THERAPY2007
- Author(s)
  Hisako Katano, Hideaki Tahara, et al
- Organizer
  Japanese Society of Gene Therapy
- Place of Presentation
  Nagoya
- Year and Date
  2007-06-30
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209042
[Presentation] ESTABLISHMENT OF THE SYSTEM TO SUPPORT EX VIVO CELL MANIPULATION APPROPRIATE FOR CLINICAL TRIALS OF GENE THERAPY2007
- Author(s)
  片野尚子, 田原秀晃, 他
- Organizer
  日本遺伝子治療学会
- Place of Presentation
  名古屋
- Year and Date
  2007-06-30
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17209042
[Presentation] PRODUCTION OF CURRENT GMP-COMPLIANT VIRAL VECTORS FOR EARLY PHASE CLINICAL TRIALS2007
- Author(s)
  佐々木勝則, 田原秀晃, 他
- Organizer
  日本遺伝子治療学会
- Place of Presentation
  名古屋
- Year and Date
  2007-06-30
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17209042
[Presentation] Potent anti-tumor effects of combination therapy using Interleukin-23 and alpha-galactosylceramide.2007
- Author(s)
  Kaneda H., Tahara H., et. al.
- Organizer
  American Association of Cancer Research
- Place of Presentation
  USA
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18612002
[Presentation] Therapeutic efficacy of the treatment with monoclonal antibody and dendritic cells genetically modified to express IL-12 in vivo.
- Author(s)
  Marimo Sato-Matsushita and Hideaki Tahara
- Organizer
  第23回日本樹状細胞研究会
- Place of Presentation
  京都国際会館、京都
- Data Source
  KAKENHI-PROJECT-25461974
[Presentation] NK cell IFN-gamma as a primary effector pathway for controlling tumor growth
- Author(s)
  小倉圭介, 松下（佐藤）まりも, 田原秀晃, 済木育夫, 早川芳弘
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25461974
[Presentation] Cancer immune escalation process triggered by activation of gamma-delta T17 cells through MyD88/IL-23 cascade
- Author(s)
  Yoshitaka Kimura, Marimo Sato-Matsushita, Takayuki Yoshimoto, Hideaki Tahara, Ikuo Saiki, Tatsuro Irimura, Yoshihiro Hayakawa
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ、千葉
- Data Source
  KAKENHI-PROJECT-25461974

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Tahara Hideaki 田原 秀晃

TAHARA HIDEAKI 田原 秀晃

TAHARA Hideaki 田原 秀晃

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Development of cancer immunotherapy using hyperfusogenic receptor-retargeted HSVPrincipal Investigator

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Preclinical Development of Cellular Gene therapy using Viral VectorPrincipal Investigator

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Development of tumor-specific immunotherapy based on the analysis of functions of dendritic cellsPrincipal Investigator

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樹状細胞機能の理解に基づく腫瘍特異的免疫誘導法の開発Principal Investigator

Tahara Hideaki 田原秀晃

TAHARA HIDEAKI 田原秀晃

TAHARA Hideaki 田原秀晃