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IMAI Kiyohiro  今井 清博

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Researcher Number 50028528
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2015: 法政大学, 生命科学部, 教授
2012: 法政大学, 生命機能学部, 教授
2008 – 2012: Hosei University, 生命科学部, 教授
2011: 法政大学, 工学部, 教授
2007: Hosei University, 工学部, 教授 … More
2002 – 2004: 法政大学, 工学部, 教授
2001: 大阪大学, 医学系研究科, 助教授
1987 – 1996: Associate professor, Osaka Univ. Medical School, 医学部, 助教授
1986: 大阪大学, 医学部, 講師
1986: 阪大, 医学部, 講師 Less
Review Section/Research Field
Principal Investigator
General physiology / Evolutionary biology / Biophysics
Except Principal Investigator
Emergency medicine / General physiology / General medical chemistry / 生物物性学
Keywords
Principal Investigator
ヘモグロビン / 分子進化 / Hemoglobin / ミオグロビン / アロステリック効果 / アミノ酸置換 / 酸素親和性 / 蛋白質工学 / 人工変異体 / 部位特異的変異導入 … More / 祖先型蛋白質 / 円口類 / 人工変異蛋白質 / Artificial mutants / Site-directed mutagenesis / ヘム蛋白質 / 分子設計 / 祖先型 / 遺伝子組換え / 逆分子進化 / 進化系統樹 / 硬骨魚類 / 魚類 / 巨大分子酸素担体 / 酸素結合 / 酸素平衡曲線 / 協同効果 / アロステリック単位 / 機能改変 / 部位指定変異導入法 / 大腸菌 / タンパク質工学 / 組換えDNA / ヘモグトビン / 部位指定変異導入 / Artificial Mutants / Site-directed Mutagenesis / Protein Engineering / Amino Acid Substitution / Recombinant DNA / Allosteric Effect / 機能分化 / 機能の模擬 / ワニ・ヘモグロビン / ウシ・ヘモグロビン / 生理機能の分化 / ワニ / 炭酸水素イオン / Protein engineering / Functional differentiation / Function mimicry / Crocodile hemoglobin / Bovine hemoglobin / リガンド親和性 / 種の適応 / Oxygen affinity / Ligand affinity / Protein engneering / Species adaptation / 酸素結合蛋白質 / 人工変異 / 分子分光学 / 分子動力学 / Oxygen binding proteins / Myoglobin / Artificial mutation / Molecular spectroscopy / Molecular evolution / Molecular dynamics / ヤツメウナギ / 酸素結合特性 / 電子常磁性共鳴スペクトル / フーリエ変換赤外線吸収 / アミノ酸配列 / フーリエ変換近赤外線吸収 / 一次構造 / 酸素平衡特性 / lamprey / hemoglobin / myoglobin / oxygen binging characteristics / electron paramagnetic resonance spectrum / Fourier-transform infrared absorption / molecular evolution / amino acid sequence … More
Except Principal Investigator
ヘモグロビン / 老化 / 赤血球 / SH3 / 酸素結合機能 / ボーア効果 / Hemoglobin / 救急蘇生学 / 人工赤血球 / 微小循環 / 脳梗塞 / 創傷治癒 / 虚血・再還流 / 酸化ストレス / 酸素ラジカル / ナノバイオ / 救命 / 救急 / エネルギー代謝 / 酸素 / 外呼吸 / 内呼吸 / 薬理学 / 人工酸素運搬体 / 虚血 / 再灌流障害 / 酸素代謝障害 / 一酸化炭素中毒 / シアン中毒 / 水素 / 人工酸素運搬対 / 再還流障害 / 蛋白質分子の立体構造形成と機能発現 / モジュール構造 / 膜蛋白質 / 二次および三次構造予知 / 変異蛋白質のデザインによる機能解析 / チトクロムP-450 / ヘモグロビン変異体 / 立体構造形成要因の解析 / 寿命 / 2,3ーDPG / ATP / エネルギ-代謝 / 変形能 / レオロジ- / Erythrocytes, / Life span, / Aging, / 2.3-DPG, / ATP, / Energy metabolism, / Deformability, / Rheology / 近紫外域CD / 紫外共鳴ラマン / 変異体 / チロシン / トリプトファン / 四次構造変化 / 高次構造変化 / 芳香族アミノ酸 / CD / 共鳴ラマン / HbM / アロステリックエフェクター / 蛋白質の機能 / 円二色性(CD) / PI3K / 異常血色素 / SrcSH3 domein / 共鳴ラマン分光 / 円二色性 / hemoglobin / near-UV CD / UV resonance Raman / mutants / tyrosine / tryptophan / quaternary structure transition / アロステリック効果 / 金属ポルフィリン / 中間状態 / 遺伝子操作 / 構造 / 2状態モデル / アロステリック / 混成ヘモグロビン / ボーアグループ / ラマン分光 / 立体構造エネルギー / Allosteric / Metalloporphyrin / Conformation / Bohr Effect / Two state model / Intermediate / 両棲類 / サンショウウオ / アフリカツメガエル / 比較生理学 / 酸素親和性 / 酸素平衡曲線 / 協同効果 / Oxygen binding function / Bohr effect / Amphibia / Salamander / Xenopus laevis / Comparative physiology Less
  • Research Projects

    (16 results)
  • Research Products

    (52 results)
  • Co-Researchers

    (48 People)
  •  Innovative Approaches for Oxygen Metabolism Disorder with Artificial Oxygen Carriers and Related Compounds

    • Principal Investigator
      KAWAGUCHI Akira
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Emergency medicine
    • Research Institution
      Tokai University
  •  Clarification of hemoglobin evolution process by reverse molecular evolutionPrincipal Investigator

    • Principal Investigator
      IMAI Kiyohiro
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Evolutionary biology
    • Research Institution
      Hosei University
  •  Utility of Innovative Artificial Oxygen Carriers for Diseases Derived From Circulatory Derangements

    • Principal Investigator
      KAWAGUCHI Akira
    • Project Period (FY)
      2008 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Emergency medicine
    • Research Institution
      Tokai University
  •  Experimental verification of acquisition of hemoprotein high-order functions by reverse molecular evolutionPrincipal Investigator

    • Principal Investigator
      IMAI Kiyohiro
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Evolutionary biology
    • Research Institution
      Hosei University
  •  Relation between the structure and function of proteins studied by the changes of tyrosine and tryptophan residues.

    • Principal Investigator
      NAGAI Masako
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Hosei University
      Kanazawa University
  •  Structure, function and evolution of cyclostomata hemoglobin and myoglobinPrincipal Investigator

    • Principal Investigator
      IMAI Kiyohiro
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biophysics
    • Research Institution
      Hosei University
      Osaka University
  •  Molecular manipulation of oxygen binding proteins and new development of precise structure-function studies on themPrincipal Investigator

    • Principal Investigator
      IMAI Kiyohiro
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biophysics
    • Research Institution
      Osaka University
  •  Study of the regulation mechanism of ligand affinity of hemoglobin by protein engineeringPrincipal Investigator

    • Principal Investigator
      IMAI Kiyohiro
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General physiology
    • Research Institution
      Osaka University
  •  Study on the differentiation of physiological function of hemoglobin using artificial mutantsPrincipal Investigator

    • Principal Investigator
      IMAI Kiyohiro
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General physiology
    • Research Institution
      Osaka University
  •  Mechanism of impaired rheology of aged erythrocytes in relation to the determinants of life span

    • Principal Investigator
      SHIGA Takeshi
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      General physiology
    • Research Institution
      Osaka University
  •  Studies on the Mechanism of Physiological Function of Hemoglobin by Using Artificial MutantsPrincipal Investigator

    • Principal Investigator
      IMAI Kiyohiro
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General physiology
    • Research Institution
      Osaka University
  •  蛋白質工学によるヘモグロビン分子機能の改変Principal Investigator

    • Principal Investigator
      今井 清博
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      Osaka University
  •  巨大分子酸素担体の分子構築と機能発現の機序Principal Investigator

    • Principal Investigator
      今井 清博
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      Osaka University
  •  蛋白質分子の立体構造形成と機能発現メカニズムに関する研究

    • Principal Investigator
      旗野 昌弘
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      Tohoku University
  •  Comparative physiological studies of regulation mechanism of hemoglobin function

    • Principal Investigator
      TYUMA Itiro
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      General physiology
    • Research Institution
      Osaka University Medical School
  •  The allosteric effect in hemoglobin.

    • Principal Investigator
      MORIMOT H.
    • Project Period (FY)
      1985 – 1987
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      生物物性学
    • Research Institution
      Faculty of Engineering Science Osaka University

All 2014 2013 2012 2011 2010 2009 2008 2007

All Journal Article Presentation Book

  • [Book] Fronteras Cientificas en el Siglo XXI (Javier Navarro, Ed., Kosmotropic salts from the Hofmeister series decrease the oxygen affinity of human hemoglobin A)2007

    • Author(s)
      A. Tsuneshige, K. Imai, T. Haga
    • Publisher
      Editorial Cordillera SAC
    • Data Source
      KAKENHI-PROJECT-19570222
  • [Journal Article] Electronic control of discrimination between O2 and CO in myoglobin lacking distal histidine residue2014

    • Author(s)
      R. Nishimura, T. Shibata, I. Ishigami, T. Ogura, H. Tai, S. Nagao, T. Matsuo, S Hirota, O. Shoji, Y. Watanabe, K. Imai, S. Neya, A. Suzuki, Y. Yamamoto
    • Journal Title

      Inorganic Chemistry

      Volume: 53 Pages: 1091-1099

    • DOI

      10.1021/ic402625s

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24225004, KAKENHI-PROJECT-24249086, KAKENHI-PROJECT-24350086, KAKENHI-PROJECT-24550189, KAKENHI-PUBLICLY-25105724, KAKENHI-PUBLICLY-25109540
  • [Journal Article] Circular dichroism of hemoglobin and myoglobin2014

    • Author(s)
      Masako Nagai M., Yoshifumi Nagai Y., Kiyohiro Imai K., and Saburo Neya S.
    • Journal Title

      Chrality

      Volume: 15

    • DOI

      10.1002/chir.22273

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249086
  • [Journal Article] Relationship between the electron density of the heme Fe atom and the vibrational frequencies of the Fe-bound carbon monoxide in myoglobin2013

    • Author(s)
      R. Nishimura, T. Shibata, H. Tai, I. Ishigami, T. Ogura, S. Nagao, T. Matsuo, S. Hirota, K. Imai, S. Neya, A. Suzuki, and Y, Yamamoto
    • Journal Title

      Relationship between the Electron Density of the Heme Fe Atom and the Vibrational Frequencies of the Fe-Bound Carbon Monoxide in Myoglobin

      Volume: 52 Pages: 3349-3355

    • DOI

      10.1021/ic3028447

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J00949, KAKENHI-PROJECT-23655151, KAKENHI-PROJECT-24249086, KAKENHI-PROJECT-24350086, KAKENHI-PROJECT-24550189, KAKENHI-PUBLICLY-23105530, KAKENHI-PUBLICLY-23108703
  • [Journal Article] Relationship between oxygen affinity and autoxodation of myoglobin.2012

    • Author(s)
      Shibata, T, Matsumoto, D;, Nishimura, R, Tai, H, Matsuoka, A, Nagao, S, Matsuo, T, Hirata, S, Imai, K, Neya, S, Suzuki, A. and Yamamoto, T.
    • Journal Title

      Inorg. Chem

      Volume: 51 Pages: 11955-11960

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22570217
  • [Journal Article] Near-UVcircular dichroism and UV resonance Ramanspectra of individual tryptophan residues inhuman hemoglobin and their changes uponthe quaternary st2012

    • Author(s)
      Nagai, M, Nagatomo, S, Nagai, Y, Ohkubo,K, Imai, K, and Kitagawa, T.
    • Journal Title

      Biochemistry

      Volume: 51 Pages: 5932-5941

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22570217
  • [Journal Article] Determination of oxygen binding properties of the individual subunits of intact human adult hemoglobin2011

    • Author(s)
      A. Sato, H. Tai, S. Nagatomo, K. Imai and Y.Yamamoto
    • Journal Title

      Bull. Chem. Soc. Jpn

      Volume: 84 Pages: 1107-1111

    • NAID

      10030215259

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22570217
  • [Journal Article] Allosteric models of hemoglobin, still evolving, In Hemoglobin: Recent Developments and Topics2011

    • Author(s)
      H. Fujimoto and K. Imai
    • Journal Title

      Research Signpost, Kerala, India (M. Nagai, ed.)

      Pages: 161-177

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22570217
  • [Journal Article] Differences in coordination states of substituted tyrosine residues and quaternary structures among hemoglobin M probed by resonance Raman spectroscopy2010

    • Author(s)
      Y. Aki, M. Nagai, Y. Nagai, K. Imai, M. Aki, A. Sato, M. Kubo, S. Nagatomo and T. Kitagawa
    • Journal Title

      J. Biol. Inorg. Chem.

      Volume: Vol. 15 Pages: 147-158

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22570217
  • [Journal Article] Diffrerences in coordination states of substituted tyrosine residues and quaternary structures among hemoglobin M probed by resonacne Raman spectroscopy2010

    • Author(s)
      Y. Aki, M. Nagai, Y. Nagai, K. Imai, M. Aki, A. Sato, M. Kubo, S. Nagatomo, T. Kitagawa
    • Journal Title

      J. Biol. Inorg. Chem. 15

      Pages: 147-158

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19570222
  • [Journal Article] Effect of heme modification on oxygen affinity of myoglobin and equilibrium of the acid-alkaline transition in metmyoglobin2010

    • Author(s)
      T. Shibata, S. Nagao, M. Fukaya, H. Tai, S.Nagatomo, K. Morihashi, T. Matsuo, S. Hirota, A. Suzuki, K. Imai and Y. Yamamoto
    • Journal Title

      J. Am. Chem. Soc.

      Volume: Vol. 132 Pages: 6091-6098

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22570217
  • [Journal Article] Molecular insight into intrinsic heme distortion in ligand binding in hemoprotein2010

    • Author(s)
      S. Neya, M. Suzuki, T. Hoshino, H. Ode, K. Imai, T. Komatsu, A. Ikezaki, M. Nakamura,Y. Furutani and H. Kandon
    • Journal Title

      Biochemistry.

      Volume: Vol. 49 Pages: 5642-5650

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22570217
  • [Journal Article] Analysis of the water binding capacity of membrane by molecular dynamics simulation.2009

    • Author(s)
      Yamaguchi J, Imai Y, Mori K, Suzuyki M, Neya S, Hoshino T.
    • Journal Title

      e-J Surface Sci Nanotech 28

      Pages: 170-176

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249072
  • [Journal Article] Functional evaluation of iron oxypyriporphyrin in protein heme pocket2008

    • Author(s)
      S. Neya, M. Suzuki, H. Ode, T. Hashimoto, Y. Furutani, H. Kandori, H. Hori, K. Imai, T. Komatsu
    • Journal Title

      Inorg. Chem. 47

      Pages: 10771-10778

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19570222
  • [Journal Article] Effect of reversed heme orientation on circular dichroism and cooperative oxygen binding of human adult hemoglobin2008

    • Author(s)
      M. Nagai, Y. Nagai, Y. Aki, K. Imai, Y. Wada, S. Nagatomo, Y. Yamamoto
    • Journal Title

      Biochemistry 47

      Pages: 517-525

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19570222
  • [Journal Article] Reduction in hemoglobin-oxygen affinity results in the improvement of exercise capacity in mice with chronic heart failure2008

    • Author(s)
      T. Watanabe, T. Takeda, S. Omiya, S. Hikoso, O. Yamaguchi, Y. Nakano, Y. Higuchi, A. Nakai, Y. Abe, Y. Aki-Jin, M. Taniike, I. Mizote, Y. Matsumura, T. Shimizu, K. Nishida, K. Imai, M. Hori, T. Shirasawa, K. Otsu
    • Journal Title

      J. Amer. College Cardiol. 52

      Pages: 779-786

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19570222
  • [Journal Article] Changes of near-UV CD spectra of human hemoglobin upon the R→T quaternary structure transition2007

    • Author(s)
      Y. Aki-Jin, Y. Nagai, K. Imai, M. Nagai
    • Journal Title

      ACS Symposium Series on New Approaches in Biomedical Spectroscopy 963

      Pages: 297-311

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19570222
  • [Journal Article] 哺乳類ヘモグロビンの協同作用とボーア効果は協調して酸素の獲得と輸送を行っている-規範タンパク質における新たな視点-2007

    • Author(s)
      張岩、今井清博、小林道頼
    • Journal Title

      生物物理 47

      Pages: 167-173

    • NAID

      110006273084

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19570222
  • [Journal Article] Oxygenation properties of extracellular giant hemoglobin from Oligobrachia mashikoi2007

    • Author(s)
      Y. Aki, T. Nakagawa, M. Nagai, Y. Sasayama, Y. Fukumori, K. Imai
    • Journal Title

      Biochim. Biophys. Res. Commun 360

      Pages: 673-678

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19570222
  • [Journal Article] Heme orientational disorder in human adult hemoglobin reconstituted with a ring Fluorinated heme and its functional consequences2007

    • Author(s)
      S. Nagao, Y. Hirai, S. Kawano, K. Imai, A. Suzuki, Y. Yamamoto
    • Journal Title

      Biochem. Biophys. Res. Commun 354(3)

      Pages: 681-685

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19570222
  • [Presentation] 硬骨魚類の祖先型ヘモグロビン Node296α・Node203β 遺伝子設計・合成お よび大腸菌内発現2012

    • Author(s)
      杉山 将,松尾高稔,関 一葉,中川太郎,今井 清博
    • Organizer
      マイクロ・ナノテクノロジー研究センター開設 10 周年記 念シンポジウム
    • Place of Presentation
      法政大学,東京都
    • Year and Date
      2012-10-13
    • Data Source
      KAKENHI-PROJECT-22570217
  • [Presentation] ヒトヘモグロビンの酸素結合機能にお ける近位ヒスチジンの役割2012

    • Author(s)
      丸山夏未,安芸弥生,長井幸史,今井清博,長友重紀,小倉尚志,北川禎三,長井雅子
    • Organizer
      第85回日本生化学会大会(2P-357
    • Place of Presentation
      福岡国際会議場,マリンメッセ 福岡,福岡県
    • Data Source
      KAKENHI-PROJECT-22570217
  • [Presentation] ヘモグロビンの自動酸化速度に対する糖類の効果2012

    • Author(s)
      上原 航,今井清博
    • Organizer
      第50回日本生物物理学会年会
    • Place of Presentation
      名古屋大学,愛知県
    • Data Source
      KAKENHI-PROJECT-22570217
  • [Presentation] トリプトファンの 近紫外円二色性及び紫外共鳴ラマンに基 づ くヘモ グロビ ンの 四次構 造変化 の解 明2012

    • Author(s)
      長井雅子,長友重紀,長井幸史,大久保賢一, 今井清博,北川禎三
    • Organizer
      第39回生体分子科学討論会要旨集
    • Place of Presentation
      東北大学,宮城県
    • Data Source
      KAKENHI-PROJECT-22570217
  • [Presentation] ヒトヘモグロビンのβ145Tyr の Thr または Leu への置換が機能と構造に与える影響2012

    • Author(s)
      一居桃子,長井幸史,今井清博,長井雅子
    • Organizer
      第50回日本生物物理学会年会
    • Place of Presentation
      名古屋大学,愛知県
    • Data Source
      KAKENHI-PROJECT-22570217
  • [Presentation] ヤツメウナギ由来の祖先型ヘモグロビン遺伝子(node25)の発現系構築2012

    • Author(s)
      幕晋一,松尾高稔,中川太郎,今井清博
    • Organizer
      マイクロ・ナノテクノロジー研究センター開設10周年記念シンポジウム
    • Place of Presentation
      法政大学,東京都
    • Year and Date
      2012-10-13
    • Data Source
      KAKENHI-PROJECT-22570217
  • [Presentation] 硬骨魚類の祖先型 ヘモグロビン遺伝子の設計・合成および その大腸菌内発現2012

    • Author(s)
      杉山 将, 松尾高稔, 関 一葉, 長井幸史, 中川太郎,今井清博
    • Organizer
      第50回日本生物物 理学会年会
    • Place of Presentation
      名古屋大学愛知県
    • Data Source
      KAKENHI-PROJECT-22570217
  • [Presentation] Expression of ancestral Cyclstomes hemoglobin Node23 gene in Escherichia coli2012

    • Author(s)
      松尾高稔,喜多かつら,尾澤雄太,中川太郎,今井清博
    • Organizer
      マイクロ・ナノテクノ ロジー研究センター開設10周年記念シンポジウム
    • Place of Presentation
      法政大学東京都
    • Year and Date
      2012-10-13
    • Data Source
      KAKENHI-PROJECT-22570217
  • [Presentation] ヒトヘモグロビンのα鎖の近位ヒスチジンのグリシンへの置換が構造と酸素結合機能に与える影響2012

    • Author(s)
      安芸弥生,長井幸史,今井清博,長友重紀,小倉尚志,北川禎三,長井雅子
    • Organizer
      第50回日本生物物理学会年会
    • Place of Presentation
      名古屋大学,愛知県
    • Data Source
      KAKENHI-PROJECT-22570217
  • [Presentation] ミオグロビンの機能調節機構の解明2011

    • Author(s)
      西村龍、松本大地、西山康太郎、柴田友和、深谷昌史、太虎林、長尾聡、松尾貴史、廣田俊、鈴木秋弘、今井清博、石上泉、小倉尚志、根矢三郎、庄司長三、渡辺芳人、山本泰彦
    • Organizer
      第38回生体分子科学討論会
    • Place of Presentation
      筑波大学,茨城県
    • Year and Date
      2011-06-23
    • Data Source
      KAKENHI-PROJECT-22570217
  • [Presentation] Hemoglobin as the normative protein2009

    • Author(s)
      K. Imai
    • Organizer
      第47回日本生物物理学会年会「Symposium "Hemoglobin revisted"」
    • Place of Presentation
      徳島
    • Data Source
      KAKENHI-PROJECT-19570222
  • [Presentation] Structure and function of Root effect fish hemoglobins2009

    • Author(s)
      S. Unzai, K. Imai, T. Yokoyama, S. Park, K. Nagai, J. Tame
    • Organizer
      第47回日本生物物理学会年会「シンポジウム"ヘモグロビンはいま"」
    • Place of Presentation
      徳島
    • Data Source
      KAKENHI-PROJECT-19570222
  • [Presentation] Relationship between oxygen affinity of myoglobin and the equililbrium constant of acid- alkaline transition in metmyoglobin2009

    • Author(s)
      T. Shibata, K. Mizuseki, S. Nagao, H. Tai, S. Nagatomo, A. Suzuki, K. Imai, Y. Yamamoto
    • Organizer
      14th International Conference on Biological Inorganic Chemistry
    • Place of Presentation
      Nagoya
    • Data Source
      KAKENHI-PROJECT-19570222
  • [Presentation] Tetramer-dimer equilibrium of chemically modified hemoglobin as studied by protein concentration- dependences of the oxygen equilibrium curve2009

    • Author(s)
      T. Inao, S. Kuriyama, K. Imai
    • Organizer
      第47回日本生物物理学会年会
    • Place of Presentation
      徳島
    • Data Source
      KAKENHI-PROJECT-19570222
  • [Presentation] Hemoglobin as the normative protein2009

    • Author(s)
      K.Imai
    • Organizer
      第47回日本生物物理学会年会
    • Place of Presentation
      徳島文理大学
    • Year and Date
      2009-11-01
    • Data Source
      KAKENHI-PROJECT-19570222
  • [Presentation] ヘム側鎖の修飾がミオグロビンの酸素親和性と酸塩基平衡に与える影響2009

    • Author(s)
      柴田友和、水関和哉、長尾聡、太虎林、長友重紀、鈴木秋弘、今井清博、山本泰彦
    • Organizer
      日本化学会第89回春期年会
    • Place of Presentation
      日大工学部(船橋市)
    • Data Source
      KAKENHI-PROJECT-19570222
  • [Presentation] Coordiation states of proximal or distal tyrosine residue in hemoglobins M and their quaternary structures probed by resonance Raman spectroscopy2009

    • Author(s)
      Y. Aki, M. Nagai, K. Imai, M. Aki, T. Kitagawa
    • Organizer
      第47回日本生物物理学会年会
    • Place of Presentation
      徳島
    • Data Source
      KAKENHI-PROJECT-19570222
  • [Presentation] 規範蛋白質としてのヘモグロビン2008

    • Author(s)
      今井清博
    • Organizer
      兵庫県立大学大学院生命理学研究科グローバルCOEプログラム「ピコバイオロジー : 原子レベルの生命科学」グローバルCOE研究集会
    • Place of Presentation
      兵庫県立先端科学支援センター
    • Year and Date
      2008-11-21
    • Data Source
      KAKENHI-PROJECT-19570222
  • [Presentation] Circular Dichroism and Oxygen Binding Properties of Human Adult Hemoglobin with Reversed Heme2008

    • Author(s)
      M. Nagai, Y. Nagai, Y. Aki, K. Imai, S. Nagatomo, Y. Yamamoto
    • Organizer
      Biophysical Society 52nd Annual Meeting and 16th International Biophysics Congress (IUPAB)
    • Place of Presentation
      Long Beach, California, USA
    • Data Source
      KAKENHI-PROJECT-19570222
  • [Presentation] Temperature- dependences of oxygen binding by myoglobin from animals with different body temperatures2008

    • Author(s)
      M. Ishida, M. Hashiride, I. Yamasaki, A. Yasuda, Y. Murakami, M. Ota, Y. Isogai, K. Imai
    • Organizer
      第46回生物物理学会年会
    • Place of Presentation
      博多
    • Data Source
      KAKENHI-PROJECT-19570222
  • [Presentation] Functional properties of mersaryl-modified hemoglobin (2)2008

    • Author(s)
      S. Kuriyama, Y. Aki, K. Imai
    • Organizer
      第46回生物物理学会年会
    • Place of Presentation
      博多
    • Data Source
      KAKENHI-PROJECT-19570222
  • [Presentation] Circular dichroism of the extracellular giant hemoglobin from annelied, Oligobrachia mashikoi2008

    • Author(s)
      T. Nakagawa, Y. Fukumori, K. Imai, M. Nagai
    • Organizer
      第46回生物物理学会年会
    • Place of Presentation
      博多
    • Data Source
      KAKENHI-PROJECT-19570222
  • [Presentation] Temperature-dependence of auto- oxidation of ancestral and closely related extant myoglobins (2)2008

    • Author(s)
      M. Ishida, Y. Murakami, A. Yasuda, I. Yamasaki, M. Ota, Y. Isogai, K. Imai
    • Organizer
      第46回生物物理学会年会
    • Place of Presentation
      博多
    • Data Source
      KAKENHI-PROJECT-19570222
  • [Presentation] Environmental alteration of three tryptophan residues in human adult hemoglobin upon ligand binding2008

    • Author(s)
      M. Nagai, Y. Nagai, Y. Aki, K. Imai, S. Nagatomo, T. Kitagawa
    • Organizer
      Proceedings of the XX1st International Conference on Raman Spectroscopy
    • Place of Presentation
      London
    • Data Source
      KAKENHI-PROJECT-19570222
  • [Presentation] 逆配向ヘムをもつヘモグロビンの酸素平衡機能と円二色性2008

    • Author(s)
      長井雅子、長井幸史、今井清博、安芸弥生、長友重紀、山本泰彦
    • Organizer
      第35回生体分子科学討論会講演要旨集
    • Place of Presentation
      兵庫県立先端科学支援センター
    • Data Source
      KAKENHI-PROJECT-19570222
  • [Presentation] Environmental alteration of three tryptophan residues in human adult hemoglobin (Hb A): A near-UV circular dichroism study2008

    • Author(s)
      K. Ohkubo, Y. Aki, K. Imai, Y. Nagai, M. Nagai
    • Organizer
      第46回生物物理学会年会
    • Place of Presentation
      博多
    • Data Source
      KAKENHI-PROJECT-19570222
  • [Presentation] 規範蛋白質としてのヘモグロビン2008

    • Author(s)
      今井清博
    • Organizer
      兵庫県立大学大学院生命理学研究科グローバルCOEプログラム「ピコバイオロジー:原子レベルの生命科学」グローバルCOE研究集会:ヘモグロビン-この未知なるもの-
    • Place of Presentation
      兵庫県立先端科学技術支援センター
    • Year and Date
      2008-11-21
    • Data Source
      KAKENHI-PROJECT-19570222
  • [Presentation] 祖先型と最近接現存種ミオグロビンの自動酸化反応の温度依存性2007

    • Author(s)
      石田学、村上祐太、安田温、山崎伊織、太田元規、磯貝泰弘、今井清博
    • Organizer
      第45回日本生物物理学会年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19570222
  • [Presentation] 酸素結合特性に対するpH及び温度の効果2007

    • Author(s)
      石田学、山崎伊織、村上祐太、太田元規、磯貝泰弘、今井清博:組み換え祖先型ミオグロビン
    • Organizer
      第45回日本生物物理学会年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19570222
  • [Presentation] ヒトヘモグロビンにおける3つのトリプトファン残基の酸素結合にともなう変化:近紫外CDおよび紫外共鳴ラマン分光による研究2007

    • Author(s)
      長井雅子、長井幸史、小久保昭秀、川口裕貴、安藝弥生、今井清博、長友重紀、北川禎三
    • Organizer
      第45回日本生物物理学会年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19570222
  • [Presentation] 有髭動物マシコヒゲムシのもつ巨大ヘモグロビンの酸素運搬機能2007

    • Author(s)
      安藝弥生、中川太郎、長井雅子、笹山雄一、福森義宏、今井清博
    • Organizer
      第45回日本生物物理学会年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19570222
  • [Presentation] 化学修飾ヘモグロビンの機能特性2007

    • Author(s)
      栗山紗子、安藝弥生、今井清博
    • Organizer
      第45回日本生物物理学会年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19570222
  • 1.  NAGAI Masako (60019578)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 20 results
  • 2.  MIYAZAKI Gentaro (50166146)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  WATANABE Manabu (30182950)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  KITAGAWA Teizo (40029955)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  MORIMOTO Hideki (20029474)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  TSUNESHIGE Antonio (30409346)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 7.  KAWAGUCHI Akira (30195052)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  KANO Koji (60038031)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  NEYA Saburo (10156169)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 10.  YAMANO Mariko (80192409)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  OKU Naoto (10167322)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  SHIRAI Mikiyasu (70162758)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  INOKUCHI Sadaki (60160008)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  HAIDA Munetaka (20208408)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 15.  KURODA Yasuhiro (40398756)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  MATSUO Takatoshi (00500737)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 17.  NAKAGAWA Taro (30401889)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 18.  MURAYAMA Chieko (50307295)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  TAMAKI Tetsuro (10217177)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  ENDO Hitoshi (10550551)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  SHIGA Takeshi (10028350)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  MAEDA Nobuji (50036464)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  ISHIMORI Koichiro (20192487)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  KOSAKA Hiroaki (60158897)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  IIZUKA Tetsutaro (30029475)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  MORISHIMA Isao (50026093)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  HORI Hiroshi (20127294)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  YAZAWA Yoichi (30000871)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  OKOUCHI Shoichi (90105859)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  SAKURAI Hiroshi (00225848)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  GO N. (50011549)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  KAJITA A. (80049113)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  TYUMA Itiro (10028269)
    # of Collaborated Projects: 1 results
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  • 34.  YOKOTA Shizuo (00191502)
    # of Collaborated Projects: 1 results
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  • 35.  旗野 昌弘 (50006293)
    # of Collaborated Projects: 1 results
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  • 36.  油谷 克英 (90089889)
    # of Collaborated Projects: 1 results
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  • 37.  齋藤 信彦 (20063125)
    # of Collaborated Projects: 1 results
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  • 38.  和田 昭允 (10011462)
    # of Collaborated Projects: 1 results
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  • 39.  須貝 新太郎 (80000727)
    # of Collaborated Projects: 1 results
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  • 40.  小西 康子 (80129238)
    # of Collaborated Projects: 1 results
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  • 41.  KAWAMURA-KONISHI Y.
    # of Collaborated Projects: 1 results
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  • 42.  SHOJI Osami
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 43.  渡辺 芳人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 44.  小倉 尚志
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 45.  廣田 俊
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 46.  松尾 貴史
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 47.  山本 泰彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 48.  太 虎林
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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